Digital Commons Network^™

Addressing Statistical Challenges In The Analysis Of Proteomics Data With Extremely Small Sample Size: A Simulation Study, Kyung Hyun Lee, Shervin Assassi, Chandra Mohan, Claudia Pedroza

Faculty, Staff and Student Publications

Background: One of the most promising approaches for early and more precise disease prediction and diagnosis is through the inclusion of proteomics data augmented with clinical data. Clinical proteomics data is often characterized by its high dimensionality and extremely limited sample size, posing a significant challenge when employing machine learning techniques for extracting only the most relevant information. Although there is a wide array of statistical techniques and numerous analysis pipelines employed in proteomics data analysis, it is unclear which of these methods produce the most efficient, reproducible, and clinically meaningful results.

Results: In this study, we compared 9 unique …

Exploring The Role Of Tissue-Resident T Cells In Neurotropic Viral Infections And Opioid-Induced Immune Disorders During Exposure And Withdrawal, Shenjian Ai

Arts & Sciences Graduate Student Theses and Dissertations

Tissue-resident T cells play a crucial role in the immune response to neurotropic viral infections and opioid-induced immune disorders. Understanding the roles of tissue-resident T cells in these contexts is essential for developing therapeutic strategies to mitigate their detrimental effects while enhancing their protective functions. The chemokine receptor CXCR6 and its ligand CXCL16 are critical in maintaining the population of tissue-resident T cells in the CNS. CXCR6 is expressed on CD8 T cells that persist in the CNS after recovery from West Nile virus infection. Research has shown that CXCL16, produced by microglia and other myeloid cells, binds to CXCR6 …

African American Male Overidentification In Special Education Services: Teacher Perspectives On The Referral Process, Amanda Gray

Student Theses and Dissertations

This qualitative narrative study explored the perceptions of public-school general education teachers on the training they received for referring students to special education. Two key aspects of this were investigated: (1) navigating the special education referral process, and (2) using individualized interventions that are effective with African American male students. The problem addressed in this study is the overidentification of African American male students in special education. This causes concern in the educational community, as students misidentified often suffer unintended consequences such as segregated learning environments, low expectations, and fewer post-secondary opportunities. Using social inequality theory as a theoretical framework, …

Antibiogram Pattern Of Enterococcus Species Among Urinary Tract-Infected Patients Visiting Tertiary Care Hospital In Karnataka, India, Sujatha Bhat, Dushan Uvindu Gunawardana, Delisha Kaur Boparai, Tharinya Kasundie Bamunusinghe

Open Access archive

Background: During the past several decades, enterococci are emerging as an important cause of healthcare-associated infections. They have developed resistance to various antimicrobials previously used for the treatment of urinary tract infections (UTIs). This study was aimed to determine the prevalence of Enterococcus species among urinary tract-infected patients in a tertiary care hospital, in Karnataka, India. Material and Methods: We have analyzed 4341 culture-positive urine samples received by microbiology laboratory during the year 2021. The bacterial identification was done by matrix-assisted laser desorption ionization-time of flight mass spectrometry. The antibiotic sensitivity was tested by automated VITEK-2® COMPACT (bioMérieux) system. Results: …

Exploring Community Adaptation To Public Safety Power Shutoff Events: Findings From Two Case Studies Of Unincorporated Mountain Communities In Southern California, Ramiro M. Brown

Master's Theses

As aging electrical infrastructure in the US continues to succumb to unyielding weather patterns brought on by climate change, there is an urgency among Investor-Owned Utilities (IOUs) to reduce the likelihood of their equipment sparking a wildfire. Public Safety Power Shutoffs (PSPS) – the intentional de-energization of the electrical grid on high fire weather danger days – have become a staple in IOU Wildfire Mitigation Plans (WMPs) since 2018 as one way to avoid wildfire ignitions via electrical infrastructure. One criticism of PSPS events is that they create their own hazard by cutting off power to thousands – sometimes millions-of …

Enhancing Cross-Cultural Communication In Low-Resource Language Conversational Agents, Hardi V. Trivedi

Master's Theses

Recent advancements in natural language processing (NLP) and large language models (LLMs) have facilitated the development of systems capable of generating human-like responses across a wide range of tasks. However, the majority of research has focused predominantly on English, overlooking the vast linguistic diversity globally. For true global inclusivity, extending research to other languages is crucial, particularly as it can significantly benefit various sectors such as business, healthcare, government, and education. A major challenge in this expansion is the scarcity of digital data available and the limited number of pre-trained models for low-resource languages. Our research specifically addresses these challenges …

The Impacts Of Recreational Infrastructure On Mammal Use Of Riparian Zones In Northern California Regional Parks, Emily A. Matthews

Master's Theses

Public lands have been important for the protection of riparian habitats; however, many public lands are also used for recreation, which can reduce mammal habitat use. Understanding how mammals are affected by recreation in riparian areas can help guide management decisions. The goal of this research is to understand the effect of recreation on mammal use of riparian habitats in two popular East Bay Regional Parks, Charles Lee Tilden and Wildcat Canyon, and to map the extent of that impact. Cameras were deployed in the riparian areas of a high, moderate, and low development site (Alvarado, Tilden, and Wildcat Canyon) …

Creatine And Depression In Rodents: A Meta-Analysis, Ruchika S. Tirupachur

Master's Theses

Traditional treatments for major depression are based on the monoamine deficiency hypothesis, and they fail to achieve remission in a substantial portion of patients. Newer evidence suggests the pathophysiology of depression is a more complex story, highlighting a need for research in alternative therapies. Mounting evidence shows a linkage between depression and the supplement creatine monohydrate (CRMH). Research in rodent models suggests that CRMH may both alleviate depressive symptoms and enhance the efficacy of standard antidepressants like SSRIs. The following study describes findings from a combined fixed- and random-effects meta-analysis based on four empirical studies investigating the effect of CRMH …

Coding Connections: Exploring Relationships Between Computer Science Learning And Mathematics Achievement In Secondary Education, Bradley Hayes

USF Tampa Graduate Theses and Dissertations

This dissertation in practice explores the intersection of computer science education, specifically computational thinking and programming, with mathematics achievement among 15-year-old students in selected English-speaking countries. The research addresses a gap in understanding whether skills developed through computer science can positively influence mathematics performance by assessing the extent to which learning in computer science transfers to mathematics.

To achieve this, a quantitative methodology was employed, incorporating pilot study data from a single school and large-scale survey data from the Programme for International Student Assessment (PISA) 2022. The analysis assessed the correlation between regular participation in programming activities and mathematics attainment, …

The Cowl - V. 88 N. 7 - November 14, 2024

The Cowl

The Cowl - student newspaper of Providence College. Vol. 88 No. 7 - November 14, 2024. 16 pages.

Single-Nuclei Transcriptomics Reveals Tbx5-Dependent Targets In A Patient With Holt-Oram Syndrome, Jeffrey D Steimle, Yi Zhao, Fansen Meng, Mikaela E Taylor, Diwakar Turaga, Iki Adachi, Xiao Li, James F Martin

Faculty, Staff and Students Publications

No abstract provided.

The Psychology Of Persuasive Precedent, Jeffrey J. Rachlinski, Andrew J. Wistrich

Law and Contemporary Problems

No abstract provided.

Spectator 2024-11-14, Editors Of The Spectator

The Spectator

No abstract provided.

Systematic Review Of Immune Checkpoint Inhibitor-Related Gastrointestinal, Hepatobiliary, And Pancreatic Adverse Events, Malek Shatila, Hao Chi Zhang, Anusha Shirwaikar Thomas, Antonio Pizuorno Machado, Sidra Naz, Nitish Mittal, Christine Catinis, Krishnavathana Varatharajalu, Carolina Colli Cruz, Eric Lu, Deanna Wu, Julie R Brahmer, Franck Carbonnel, Stephen B Hanauer, Bret Lashner, Bryan Schneider, John A Thompson, Michel Obeid, David P Farris, Yinghong Wang

Faculty, Staff and Student Publications

Gastrointestinal immune-related adverse events (GI irAEs) are common manifestations of immune checkpoint inhibitor (ICI) toxicity. We present a comprehensive systematic review of the incidence, management, and clinical course of irAEs across the entire GI system, including the luminal GI tract, liver, and pancreas. MEDLINE, Embase, Web of Science Core Collection, and Cochrane Library were used to conduct this review. All studies pertaining to GI irAEs were included. Both abstracts and full manuscripts were eligible if they included human subjects and were written in the English language. Articles not available in English, animal studies, or research not specific to GI toxicity …

Sustainable Futures In A Changing Climate, Dale Mineshima-Lowe, Aideen Foley

GHEA21 Open Educational Resources

Sustainable Futures in a Changing Climate is an openly available syllabus and reading list made for educators to adapt and adopt for their own classroom needs.

How Secondary Disciplinary Teachers Integrate Literacy Strategies To Improve Outcomes On State Assessments, Miracle T. Brewington

Walden Dissertations and Doctoral Studies

According to recent research, secondary disciplinary teachers’(DTs) role in increasing disciplinary literacy skills is vital. The problem in this urban school district in the Southern United States was that middle school DTs acknowledge they struggle to integrate literacy strategies in their specific disciplines to improve reading outcomes on state assessments. Guided by Shanahan and Shanahan’s disciplinary framework and Knowles’s theory of andragogy, the purpose of this study was to investigate DTs’ perceptions on integrating literacy strategies to improve reading outcomes on state assessments. A basic qualitative design was used with 10 purposefully selected secondary DTs using one-to-one, semistructured interviews. Data …

Racial And Ethnic Disparities In Perceived Health Status Among Patients With Cardiovascular Disease, Marjan Zakeri, Lincy S Lal, Susan M Abughosh, Shubhada Sansgiry, E James Essien, Sujit S Sansgiry

Faculty, Staff and Students Publications

Introduction: Understanding health outcomes among people with cardiovascular disease (CVD) is crucial for improving treatment strategies and patient quality of life. This study investigated racial and ethnic disparities in perceived health status among non-Hispanic Black, Hispanic, and non-Hispanic White adults with CVD.

Methods: The study had a retrospective cross-sectional design and used data from the Medical Expenditure Panel Survey spanning 8 calendar years (2014-2021). The study population consisted of adults diagnosed with various CVDs. We used ordinal logistic regression models adjusted for demographic and socioeconomic characteristics, CVD severity, comorbidities, and health care expenditures to assess racial and ethnic differences in …

Information About A Racial Demographic Shift May Influence Tolerance For Outgroup Contact, Yvonne N. Phan

Master's Theses

When exposed to information about a demographic shift towards a non-White majority in America, White individuals tend to prefer interactions and settings within their own ethnic group over minority ethnic groups. This behavior may suggest that future inter-racial dynamics in the U.S. could be characterized by resistance from White individuals. To understand how other racial groups respond to information about a racial demographic shift, I collected data on three measures of outgroup tolerance from a multiracial sample of students from San Jose State University’s participant database after exposing them to information about a racial demographic shift driven by a Hispanic …

The Moderating Role Of Meaningful Work On The Relationship Between Loss Of Self-Identity And Psychological Well-Being In Retired Collegiate Athletes, Sarah M. Kurd

Master's Theses

Collegiate athletes are a focal point for many universities. These student-athletes work most of their lives to make it to the university level. Many collegiate athletes aspire to make it to the professional level after they graduate from college, but only a rare handful make it to the top. The rest of the athlete population retires and is placed into a world of “normalcy,” but the transition out of athletics can be very challenging, impacting a person’s psychological well-being. Most of these athletes will have to work a professional job after leaving sports. The present study aimed to examine the …

November 14, 2024, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.

Multi-Dimensional Visualization Strategies Using Web Scraping Tools: A Word Formation Synthesis Case Study For Russian Verbs Of Sound, John Simmons

Graduate Student Research & Creative Works

No abstract provided.

Internet Of Medical Things: Integrating Machine Learning And Wearables For Healthcare, Jingwen Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

The Internet of Medical Things (IoMT), which integrates Internet of Things technologies into healthcare, has become a powerful tool for enhancing health monitoring and predicting clinical outcomes. By leveraging wearable devices, IoMT facilitates continuous, cost-effective, and convenient tracking of patients' health conditions over time. This dissertation applies data-driven methods to address critical clinical challenges involving wearable devices. Specifically, it focuses on three significant clinical problems: (1) indoor contact tracing for healthcare workers using Bluetooth Low Energy (BLE) beacons, (2) predicting surgical outcomes using wearable data, and (3) developing robust models for surgical outcome prediction that account for patient variability using …

Internet Of Medical Things: Integrating Machine Learning And Wearables For Healthcare, Jingwen Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

The Internet of Medical Things (IoMT), which integrates Internet of Things technologies into healthcare, has become a powerful tool for enhancing health monitoring and predicting clinical outcomes. By leveraging wearable devices, IoMT facilitates continuous, cost-effective, and convenient tracking of patients' health conditions over time. This dissertation applies data-driven methods to address critical clinical challenges involving wearable devices. Specifically, it focuses on three significant clinical problems: (1) indoor contact tracing for healthcare workers using Bluetooth Low Energy (BLE) beacons, (2) predicting surgical outcomes using wearable data, and (3) developing robust models for surgical outcome prediction that account for patient variability using …

University Of Northern Iowa Graduate Council Minutes, November 14, 2024, University Of Northern Iowa. Graduate Council.

Documents - Graduate Council

Meeting minutes from the Graduate Council of the University of Northern Iowa.

Montana Kaimin, November 14, 2024, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Longitudinal Pedestrian Safety Trends By Vehicle Type And Model: A 2015-2022 Study Of Texas, Olivia Tafoya

Civil Engineering ETDs

We observed pickup trucks, SUVs, and passenger cars and their two most popular vehicle models across Texas from 2015 through 2022. For each vehicle type and model, we obtained all reported pedestrian crashes, counts of registered vehicles, and vehicle design characteristics. Results suggest that older vehicles are more likely to seriously injure or kill a pedestrian than newer ones. They also indicate that SUVs were more deadly, after controlling for exposure using the number of registered vehicles, than other vehicle types. Of the models studied, the full-size SUVs proved to be particularly dangerous for pedestrians, being 2.08 times more likely …

Kenyon Collegian - November 14, 2024

The Kenyon Collegian

No abstract provided.

Faint Glimmers: Redrawing The Housewife In Yamada Murasaki's Talk To My Back, Ceres Lovelace

Dissertations and Theses

Yamada Murasaki's seminal manga collection Talk to My Back, originally titled Shinkirari, tells a story of a woman's gradual journey toward agency within the constraints of a nuclear patriarchal family. Set within the everyday suburban life of Chiharu in 1980s Japan, Yamada uses subtle visual cues and restrained narrative techniques to illustrate her protagonist's struggles and quiet breakthroughs as she questions her identity and renegotiates her role as a housewife and mother.

By exploring the often-overlooked inner world of a housewife, Yamada scrutinizes traditional gender roles and reveals the burden and psychological toll of the emotional labor imposed on …

The Evaluation Of Health Recommender Systems: A Scoping Review, Rohit Shankar

Peninsula Medical School

Background: People often look online for information about health concerns, but the vast amount of available and unregulated content can cause misinformation and potential harm. Health recommender systems (HRSs) can address this issue by recommending personalised health information. Previous research has evaluated individual systems, but there is a lack of reviews synthesising their evaluation findings. Such a synthesis is needed to ensure that future recommender designs have a positive impact on target health or behavioural outcomes. Objective: This review aimed to provide a summary of the evidence obtained from previous studies evaluating HRSs and highlight methodological considerations and gaps in …

Evaluasi Efektivitas Pelaksanaan Program Bilingual Mata Pelajaran Matematika, Rafinda Putri Mentari, Amat Jaedun, Rina Safitri

PYTHAGORAS : Jurnal Matematika dan Pendidikan Matematika

The purpose of this research is to find out the process aspects, product aspects, and results of the implementation after evaluating the bilingual program in mathematics at SMP Muhammadiyah 3 Yogyakarta. The research was conducted using the Mix Methods approach, beginning with the use of qualitative methods followed by quantitative. The CIPP evaluation model is used in this study with a focus on two components, namely the process component and the product component. This evaluation research uses qualitative research data obtained through interview notes, observations, and document studies. Sources of data were obtained from teachers and students of bilingual class …