Digital Commons Network^™

Inhibition Of The Ufd-1-Npl-4 Complex Triggers An Aberrant Immune Response In Caenorhabditis Elegans, Rajneesh Rao, Alejandro Aballay, Jogender Singh

Faculty, Staff and Student Publications

The UFD-1 (ubiquitin fusion degradation 1)-NPL-4 (nuclear protein localization homolog 4) heterodimer is involved in extracting ubiquitinated proteins from several plasma membrane locations, including the endoplasmic reticulum. This heterodimer complex helps in the degradation of ubiquitinated proteins via the proteasome with the help of the AAA+ATPase CDC-48. While the ubiquitin-proteasome system is known to have important roles in maintaining innate immune responses, the role of the UFD-1-NPL-4 complex in regulating immunity remains elusive. In this study, we investigate the role of the UFD-1-NPL-4 complex in maintaining

Prabowo Subiyanto’S Legal Political Direction: Critical Discourse Analysis On Law Enforcement In The First Debate Of The 2024 Presidential Election, Khoiron Khoiron, Ahmad Syaifudin

Jurnal Wacana Politik

This article examines how presidential candidates have produced legal discourses that are used as political instruments in winning the political contestation of the Indonesian national presidential election in 2024. Through political discourse, Prabowo Subiyanto aimed to influence the public for his victory. As a result, he emerged victorious, proving that political discourse in public debates can successfully deconstruct, influence, and steer the way of thinking and can lead voters’ preferences. The main argument in this article is that discourse as a political instrument is not empty, but behind the discourse is a form of political truth operation produced for certain …

Longitudinal Associations Of Epigenetic Aging With Cognitive Aging In Hispanic/Latino Adults From The Hispanic Community Health Study/Study Of Latinos, Myriam Fornage, Wassim Tarraf, Rui Xia, Adriana Ordonez, Tamar Sofer, Freddie Márquez, Bharat Thyagarajan, Gregory A Talavera, Linda C Gallo, Charles Decarli, Hector M González

The Brown Foundation: Institute of Molecular Medicine

Due to the paucity of longitudinal DNA methylation data (DNAm), especially among Hispanic/Latino adults, the association between changes in epigenetic clocks over time and cognitive aging phenotypes has not been investigated. This longitudinal study included 2671 Hispanic/Latino adults (57 years; 66% women) with blood DNAm data and neurocognitive function assessed at two visits ~7 years apart. We evaluated the associations of 5 epigenetic clocks and their between-visit change with multiple measures of cognitive aging that included a global and domain-specific cognitive function score at each visit, between-visit change in global and domain-specific cognitive function score, and MCI diagnosis at visit …

Development Of A Patient-Centered Outcome Tool For Blepharospasm: A Stepwise Modified Delphi Study, Brian D Berman, Fares Qeadan, Amanda D Henderson, Andrew R Harrison, Giovanni Defazio, Mark Hallett, Gamze Kilic-Berkmen, Laura Wright, Samantha Pentecost, Paul Reyes, Anna Tingin, Joseph Jankovic, Jane Boyd, Charlene Hudgins, Janet Hieshetter, Joel S Perlmutter, Hyder A Jinnah, Sarah Pirio Richardson

Faculty, Staff and Students Publications

Blepharospasm (BSP) is characterized by excessive orbicularis oculi muscle activity leading to abnormal blinking and involuntary eyelid closure. Botulinum neurotoxin (BoNT) injections are the main treatment for BSP, but they only partially and transiently relieve symptoms, leading to a waxing and waning therapeutic response. A patient-centered outcome (PCO) tool that measures BSP symptoms in a simple and efficient way could inform the development of better treatments. Using a stepwise modified Delphi approach, potential PCO items were first identified using the Dystonia Coalition Database with data from over 200 individuals with BSP who had provided responses to existing clinical assessment scales. …

Characterizing Secondary Flow Structures Over Scaled Solar Arrays And Investigating Impact Of System Yaw Angle, Katie Nicole Taylor

Dissertations and Theses

This study investigates Prandtl's secondary flows of the second kind within the turbulent boundary layer over a newly defined type of surface roughness, e-type, which is characterized by roughness elements that are elevated from the wall. This e- type roughness is modeled after photovoltaic (PV) solar panels and its study driven by establishing a more robust understanding into how flow moves through solar arrays as the demand for renewable energy continues to grow.

Wind tunnel experiments using particle image velocimetry (PIV) were conducted over a scaled array of panels and explored how shifting the yaw angle of the …

Developing Workflows For Passive Acoustic Detection Of Bedload Transport, Quinn Morgan

Dissertations and Theses

Bedload transport is defined as the amount of sediment, including gravel and rocks, traveling down stream. Monitoring bedload transport is important for river safety, hydrological studies and conservation efforts. Existing methods of directly measuring bedload transport (or bedload flux) involve lowering a collection device into a river and measuring the sediment collected; which can be expensive and time consuming. Hydroacoustic sensors, such as hydrophones, have had success tracking bedload flux remotely. This works by measuring the relatively high frequency of sediment impacts to map onto total bedload transported. No perfected method for detection of sediment generated noise (SGN) currently exists. …

Barriers Beyond Bars: Examining Experiences Of Students With Criminal Records, Anakin Rivera Ramirez

Dissertations and Theses

As educational opportunities, particularly prison education programs, continue to expand for incarcerated individuals, this study, which included two participants, one formerly incarcerated and one who pleaded guilty to avoid incarceration, suggests that those who plead guilty to avoid prison may enter college without the structured reintegration resources available to their incarcerated peers. While substantial research has explored the school-to-prison pipeline phenomenon in K-12 settings, fewer studies have examined its impact on students with criminal records navigating higher education. Grounded in Critical Race Theory (CRT) in education, this study seeks to understand the experiences of carceral system-impacted students of color in …

Transbaffle, Endocardial Systemic Right Ventricle Cardiac Resynchronization Therapy In D-Transposition Of The Great Arteries, Nathan R Smith, Dhaval R Parekh, Enrique Garcia-Sayan, Kishan Dwarakanath, Wilson W Lam

Faculty, Staff and Students Publications

Background: Systemic right ventricular (SRV) cardiomyopathy commonly complicates d-transposition of the great arteries with previous atrial switch repair. Cardiac resynchronization therapy (CRT) is an effective therapy but may be difficult to achieve conventionally via coronary sinus (CS) lead implantation.

Case summary: A 58-year-old man with a history of d-transposition of the great arteries and prior Mustard procedure presented with progressive dyspnea and QRS duration >200 milliseconds. No suitable CS branch was identified; therefore, we delivered CRT with endocardial SRV lead implantation via a VersaCross radiofrequency wire system. The patient experienced a QRS morphology similar to native conduction and an improvement …

High Beta Power In The Ventrolateral Prefrontal Cortex Indexes Human Approach Behavior: A Case Study, Nicole R Provenza, Sameer V Rajesh, Gabriel Reyes, Kalman A Katlowitz, Lokesha S Pugalenthi, Raphael A Bechtold, Nabeel Diab, Sandesh Reddy, Anthony K Allam, Ajay D Gandhi, Katherine E Kabotyanski, Kasra A Mansourian, Jonathan H Bentley, Jordan R Altman, Saurabh Hinduja, Nisha Giridharan, Garrett P Banks, Mohammed Hasen, Ben Shofty, Sarah R Heilbronner, Jeffrey F Cohn, David A Borton, Eric A Storch, Jeffrey A Herron, Benjamin Y Hayden, Mary L Phillips, Wayne K Goodman, Sameer A Sheth

Faculty, Staff and Students Publications

Deep brain stimulation (DBS) of the ventral capsule and ventral striatum (VC/VS) is an effective therapy for treatment-resistant obsessive–compulsive disorder (trOCD). DBS initiation often produces acute improvements in mood and energy. These acute behavioral changes, which we refer to as “approach behaviors,” include increased social engagement and talkativeness. We investigated the relationship between stimulation amplitude, spectral power in the ventrolateral prefrontal cortex (vlPFC), and speech rate in one male patient with trOCD implanted with bilateral VC/VS DBS leads and subdural electrodes adjacent to the orbitofrontal cortex and vlPFC. Several times over the first 24 weeks of therapy, we conducted experiments …

Harnessing Ai And Iot For Advancing Sustainable Development Methods, Najm A. Aleessawi, Soud Elmaskali

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

The integration of Artificial Intelligence (AI) and the Internet of Things (IoT) offer transformative potential for advancing sustainable development, aligning with the United Nations’ 2030 Agenda for Sustainable Development. This study conducts a systematic literature review (SLR) of 72 peer-reviewed studies (2019–2025) to explore innovative models, methods, and applications of AI-IoT in promoting sustainability. Grounded in systems theory, socio-technical systems, and sustainability science, the findings highlight prevalent models, such as smart cities and precision agriculture, as well as advanced methods like machine learning and edge AI, with applications across energy, agriculture, healthcare, transportation, and water management. Key outcomes include 15–25% …

Sustainable Assessment: A Proposed Model-Based Frame Of Reference To Actualize Sustainable Assessment Via Feedback And Technology Enhancement, Abd-Al-Hameed Mustafa Mahmoud Jabsheh, Jaafar Wasfi Abu Saa Jwa

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

This article aimed to carefully examine the available relevant literature, through a survey, to explore the theoretical basis of sustainable assessment, as a newly emerging concept dictated by the rapid trends and developments of the twenty-first century. The article also aims to propose a model-based framework for achieving sustainable assessment practices within traditional assessment practices. To achieve this dual objective, the researcher followed an analytical and developmental approach, based on most of the limited relevant literature available, to define the theoretical boundaries of sustainable assessment as a concept and as a process. Furthermore, this analytical and developmental approach was formulated …

فعالية برنامج رياضي لتنمية المهارات الاجتماعية لدى الصم, Nashwan Abdullah Nashwan, Hani Sulaiman Alkhaledi, Ayat J. Nashwan

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدفت الدراسة إلى الكشف عن فعالية برنامج رياضي لتنمية المهارات الاجتماعية لدى الصم، وقد تألف مجتمع الدراسة من (60) أصماً في محافظة الزرقاء، وتكونت عينة الدراسة من (20) أصماً من طلبة الصف التاسع الأساسي ضمن الفئة العمرية 14 عاماً، وتم اختيار عينة الدراسة بطريقة عشوائية تم تقسيمها الى مجموعة تجريبية تتكون من عشرة أصماء، وأخرى ضابطة تتكون من عشرة أصماء، واستخدم الباحثون المنهج شبه التجريبي، وتم تصميم مقياس المهارات الاجتماعية لدى الصم، وحصل المقياس على درجات جيدة من الصدق والثبات، وأظهرت النتائج بعد تطبيق البرنامج فعالية البرنامج لتنمية المهارات الاجتماعية لدى الصم، وتم تقديم عدد من المقترحات لمساعدة هذه الفئة …

مدى تقبل مديري المدارس ومعلمي التعليم المهني (Betc) وأولياء الأمور للتعليم الدامج في المدارس الحكومية الأردنية في ظل التحول الرقمي, Ibrahim Ahmad Mlhem, Roa’A Bas’Sam Al-Khatib, Rawan Salameh Al-Iroud

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدفت الدراسة إلى الكشف عن مدى تقبل مديري المدارس ومعلمي التعليم المهني وأولياء الأمور للتعليم الدامج في المدارس الحكومية الأردنية في ظل التحول الرقمي. اعتمدت الدراسة المنهج الوصفي التحليلي، وتكوَّنت عينة الدراسة من (185) فرداً، تم اختيارهم بالطريقة العشوائية، وتم تطوير الاستبانة؛ إذ تكونت من (35) فقرة موزَّعة على (3) محاور، وهي الفوائد التي تعود على مديري ومعلمي مدارس التعليم المهني، وأولياء أمور الطلبة من ذوي الإعاقة، وتمَّ توزيع الاستبانة إلكترونياً على عينة الدراسة. أظهرت النتائج مدى تقبُّل مديري المدارس ومعلمي التعليم المهني وأولياء الأمور للتعليم الدامج في المدارس الحكومية الأردنية في ظل التحول الرقمي، فقد جاءت مرتفعة، ودلَّت على …

درجة استخدام معلمي اللغة الإنجليزية مهارات التدريس داخل غرف مصادر التعلم لدى الطلبة ذوي صعوبات التعلم, Batool Abdel Kareem Ahmad Jaradat

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدفت هذه الدراسة إلى التعرف على درجة استخدام معلمي اللغة الإنجليزية مهارات التدريس داخل غرف مصادر التعلم لدى طلبة ذوي صعوبات التعلم حيث بلغت عينة الدراسة (49) معلماً ومعلمة من معلمي اللغة الإنجليزية للطلبة ذوي صعوبات التعلم، تم اختيارهم بالطريقة العشوائية في مدارس محافظة إربد، ولتحقيق أهداف الدراسة، تم استخدم المنهج الوصفي المسحي، ولغايات تحقيق أهداف الدراسة تم تطوير أداة لقياس مهارات التدريس داخل غرف مصادر التعلم، وأظهرت النتائج أن المتوسطات الحسابية لاستجابات عينة الدراسة على مقياس درجة استخدام معلمي اللغة الإنجليزية مهارات التدريس داخل غرف مصادر التعلملدى طلبة ذوي صعوبات التعلم في محافظة إربد جاءت متوسطة، كما أظهرت النتائج …

Psychometric Properties Of Epds And Phq-9 Tools For Partners Of Pregnant Women In Karachi, Pakistan, Salima Sulaiman, Ilona S. Yim, Aliyah Dosani

International Nursing Research Congress (INRC)

Background: The Edinburgh Postnatal Depression Scale (EPDS) and Patient Health Questionnaire-9 (PHQ-9) are widely used to measure perinatal depression, which can negatively affect children's emotional, behavioral, and developmental well-being (Niel & Payne, 2020; Ashraf et al., 2023). Male partners in low- and middle-income countries (LMIC) are at higher risk for perinatal depression but remain significantly underrepresented in research (Rao et al., 2020). No studies have explored the factor structure of the EPDS and PHQ-9 for male partners in LMIC. This study aims to evaluate the psychometric properties of the EPDS and PHQ-9 for male partners during the antenatal period in …

A Feminist Analysis Of Kenyan Women’S Use Of Hiv Pre-Exposure Prophylaxis During Pregnancy, Marin Strong, Tessa Concepcion, Felix Abuna, Eunita Akim, Helen Aketch, Lauren Gomez, Bih Moki Suh, Emma Mukenyi, Nancy Ngumbau, Jerusha Nyabiage Mogaka, Sarah Obatsa, Ben Ochieng Odhiambo, Caroline Omom, Salphine Watoyi, Kenneth Ngure, Kristin M. Beima-Sofie, Grace C. John-Stewart, John Kinuthia, Jillian Pintye

International Nursing Research Congress (INRC)

Background: HIV incidence remains high among pregnant and postpartum women in Kenya despite access to HIV pre-exposure prophylaxis (PrEP).1–4 Male partners influence women’s individual PrEP decisions,5–7 yet few studies evaluate community-level gender and power dynamics. Aligned with calls for feminist global health research,8,9 we explored gender-based determinants and structural challenges of pregnant women’s PrEP use through a feminist lens.

Methods: We conducted focus group discussions (FGDs) in English, Dholuo, and Swahili with healthcare workers (HCW) and community advisory board (CAB) members of a randomized trial (NCT04472884) that enrolled pregnant women initiating PrEP at antenatal clinics in western Kenya.10 FGD …

Mental Health Awareness For Carers And Parents Of Young People With Migrant Backgrounds In Australia, Bindu Anna Joseph, Robeena Emmanuel

International Nursing Research Congress (INRC)

Australia is a multicultural nation with 30% of people born overseas (Australian Bureau of Statistics, 2023). Mental illness is highly prevalent among migrants with delayed help-seeking (World Health Organisation, 2021). Addressing the unique mental health care needs of these communities is paramount for improving inclusive and timely mental health care. ). Indian – born population is the second largest migrant community in Australia (Department of Health and Aged Care). Addressing the unique mental health care needs of these communities is paramount for improving inclusive and timely mental health care. The current phase of this research focused on Indian migrants.

This …

Substance Use In Nursing: Barriers And Facilitators In Returning To Work Under Monitoring, Jordan Ferris, Marian Wilson, Janessa M. Graves, Victoria Sattler

International Nursing Research Congress (INRC)

Background: The US is currently experiencing a substance use epidemic, with overdose deaths rising significantly. Substance use disorders (SUD) affect 17.3% of individuals aged 12 or older, including nurses (RNs) who face unique occupational stressors. RNs with SUD pose risks to both personal & patient safety. Regulatory bodies often impose monitoring & disciplinary actions on RNs with SUD, creating challenges for their return-to-work (RTW). Little is known about what supports & hinders successful return-to-work for RNs after substance use discipline

Methods: This study used Group Concept Mapping (GCM) to identify & prioritize facilitators and barriers in the RTW process for …

Navigating Interpersonal Connections: Relationships Of Pregnant Women Following Hiv Diagnosis, Andile Glodin Mokoena-De Beer, Sister Vanessa Mahlangu, Eugene Musiiwa Makhavhu

International Nursing Research Congress (INRC)

HIV remains a complex and public health concern in South Africa. The country’s population by mid-year 2024 was 63,02 million with 8,0 million estimated to be living with HIV. The prevalence rate of HIV in the country is approximately 12,7% with 4 900 00 women living with HIV by 2023, of these women 257 171 were pregnant women receiving antiretroviral therapy (ARVs) to prevent mother to child transmission^1,2. Pregnancy is a complex phenomenon linked to heighted anxiety about the birth processes and safety of the unborn baby. An HIV diagnosis at this time could worsen the mental wellbeing …

Losing All Faith In Women’S Healthcare: Women’S Experience With Pelvic Congestion Syndrome Pain, Sarah E. Patel, Sarah Mary George, Mercedez Dowah Boateng, Mei R. Fu

International Nursing Research Congress (INRC)

Purpose: Pelvic congestion syndrome (PCS) is an underdiagnosed cause of chronic pelvic pain, which accounts for nearly 30% of gynecological visits. Chronic pelvic pain due to PCS is often exacerbated from long periods of standing or walking, sexual intercourse, and menstruation. Research on PCS mainly uses quantitative approaches that focused on evaluating the effects of pharmacological or medical procedures for PCS and associated pain and symptoms. There is limited evidence that provides deep understanding of the experiences of chronic pelvic pain from the women’s perspectives. Using a qualitative, descriptive phenomenological design, the purpose of this study was to describe …

Using The Introduce-Present-Reinforce-Debrief Model In International Nursing Leadership Education, Lu-Yen Anny Chen, Michelle King-Okoye, Cheng-Pei Lin

International Nursing Research Congress (INRC)

Introduction: Taiwanese Students have found it challenging to engage in English-Medium Instruction (EMI) course, due to English not being their native language, particularly in leadership courses. Many students experience difficulties in comprehending the course content thoroughly before participating in discussions, which affects their ability to express themselves clearly. To address this, the I(ntroduce)-P(resent)-R(einforce)-D(ebrief) teaching model, as proposed by Lai (2023), was implemented in an international leadership course. This four-stage cyclic model incorporates multimodal inputs and interactive activities to enhance students' understanding and application of nursing leadership.

Methods: This study employed semi-structured face-to-face interviews to explore students' experiences pre- and post-the …

Psychometric Properties Of The Chinese Version Of The Clinical Nurses Grit Scale In Employed Nurses, Chiu-Yueh Yueh Yang, Muhsi Young

International Nursing Research Congress (INRC)

Background: Grit, recognized as a positive psychological trait, significantly influences the intention of employed nurses to remain in their workplace. The Clinical Nurses Grit Scale (CN-GRIT), initially developed by Korean scholars, has been employed to assess grit in clinical nursing environments. However, a Chinese version of the Grit Scale specifically designed for evaluating the grit of nurses does not currently exist.

Purposes: This study aimed to: (1) translate the original English version of the CN-GRIT into a traditional Chinese version (TC-CN-GRIT), (2) confirm its factor structure, and (3) analyze its psychometric properties among newly employed nurses.

Methods: A psychometric study …

Matrescence, Erin Kunz

The Cicadian

Kunz reflects on her transformation into motherhood, describing the physical, emotional, and psychological shifts that accompany the process known as matrescence. Through vivid memories of childhood and early parenting, she explores the complexities of maternal love, especially for women who did not receive unconditional love themselves. Her rocking chair becomes a symbol of nurturing and endurance, where she gave everything to her children while grappling with her own identity. Erin also highlights the supportive role of her partner, challenging traditional gender norms and celebrating shared caregiving. As her children grow, she mourns the environmental changes that have altered the …

Fine-Tuning A Domain-Specific Language Model For Truss Structural Analysis, Rajon Dey, Weidong Wu, Yu Liang, Joseph Owino, Ignatius Fomunung, Mbakisya A. Onyango

UTC Spring Research and Arts Conference

This research investigates the feasibility of fine-tuning a domain-specific language model (LLM) to enhance the accuracy and accessibility of truss structural analysis. General-purpose AI models, such as ChatGPT, often struggle with engineering-specific problems due to insufficient domain knowledge. To address this, we propose fine-tuning a small LLM tailored for structural engineering tasks, with truss analysis using the stiffness method as a case study. The project leverages a curated dataset of textual and diagrammatic inputs from engineering textbooks, manuals, and solved examples. Image-to-text tools will translate structural diagrams into machine-readable formats, reducing data preparation costs while maintaining numerical precision. Fine-tuning involves …

The Prospector, September 9, 2025, Utep Student Publications

The Prospector

No abstract provided.

Beneficial Effects Of Performlytetm, A Prodosomed Phytonutrient-Enriched Electrolyte Formulation, In Enhancing Neuro-Muscular Synergy, Immune Competence, Cellular Aerobic Glycolysis And Sports Performance, Bernard William Downs, Samudra P. Banik, Bruce S. Morrison, Tandra Chakraborty, Manashi Bagchi, Sanjoy Chakraborty, Steve Kushner, Debasis Bagchi

Publications and Research

An optimised sports nutrition formulation achieving the correct blend of electrolytes with antioxidants and vitamins is integral towards meeting the demanding performance in professional sports arena. In this work, we describe a pilot study carried out to understand the effect of a novel phytonutrient- and electrolyte-fortified sports nutrition composition, PerformLyte^TM, developed in our laboratories, in boosting the performance of trained male cyclists. PerformLyte^TM is a unique fortified formulation comprising of polyphenolic antioxidants, flavonoids, and anthocyanins, as well as carotenoids, sulforaphanes, exotic spices, sea water-derived electrolytes, and vitamin C, encapsulated in proprietary patent-pending Prodosome absorption technology, enabling sustained …

Staff Education On Mindfulness-Based Therapy To Address Compassion Fatigue, Samson Ajibola Omowumi

Walden Dissertations and Doctoral Studies

The nature of nursing practice—persistent exposure to patient suffering—often results in compassion fatigue for staff. Compassion/emotional fatigue can affect nurses’ mental well-being, which can manifest in burnout, decreased empathy, and emotional numbness. These outcomes can eventually reduce job satisfaction for nurses and nursing assistants, increase errors during patient care, and lead to poorer patient outcomes. Prioritizing caregivers' mental health may improve the quality of nursing care. Mindfulness-based therapy (MBT) is an approach that may ensure the mental health and emotional stability of those who care for patients while also being a comparatively easy, accessible, and affordable tool. The goal of …

Intelligence Architectures And Machine Learning Applications In Contemporary Spine Care, Rahul Kumar, Conor Dougherty, Kyle Sporn, Akshay Khanna, Puja Ravi, Pranay Prabhakar, Nasif Zaman

SKMC Student Presentations and Publications

The rapid evolution of artificial intelligence (AI) and machine learning (ML) technologies has initiated a paradigm shift in contemporary spine care. This narrative review synthesizes advances across imaging-based diagnostics, surgical planning, genomic risk stratification, and post-operative outcome prediction. We critically assess high-performing AI tools, such as convolutional neural networks for vertebral fracture detection, robotic guidance platforms like Mazor X and ExcelsiusGPS, and deep learning-based morphometric analysis systems. In parallel, we examine the emergence of ambient clinical intelligence and precision pharmacogenomics as enablers of personalized spine care. Notably, genome-wide association studies (GWAS) and polygenic risk scores are enabling a shift from …

Return To Sport And Performance Outcomes After Hand Fractures In Professional Baseball Players, Ryan W. Paul, Sean M. Wilson, Gaston Davis, Amit Syal, Steven B. Cohen

Rothman Institute Papers

BACKGROUND: About 7% of injuries in the Major League Baseball (MLB) involve the hand. Fractures of the hand are not uncommon in professional baseball players while fielding or from being hit by a pitch while batting; however, the outcomes of professional baseball players treated both operatively and nonoperatively are unclear.

PURPOSE/HYPOTHESIS: The purpose of this study was to report the return-to-sport (RTS) rate, RTS time, and performance outcomes in professional baseball position players who sustained a hand fracture. The secondary purpose was to compare outcomes between positions and between operatively versus nonoperatively treated players. It was hypothesized that there would …

The Effects Of Tfeα And Promoter Sequence On Early Events In Archaeal Transcription Initiation, Madolyn Toli

Dissertations and Theses

Expression of genes is dependent on promoter sequences in DNA, which direct transcription by RNA polymerase. Transcription factors interact with promoters and RNAP and are often conserved and are essential for proper gene expression. In this thesis, a functional region of archaeal TFEα, homologous to eukaryotic TFIIEα, has been identified, and specific amino acids in these regions have been determined to have significant importance in TFEα's ability to promote transcription in early initiation. All three Domains of life encode a 16S rRNA promoter, which is responsible for production of the 16S portion of ribosome. Transcription with this promoter is not …