Digital Commons Network^™

Future Prospects Of Pediatric Lung Transplantation, Ernestina Melicoff, David Moreno Mcneill, Christian Benden

Faculty, Staff and Students Publications

This special issue of the Journal of Heart Transplantation Open is dedicated to Pediatric Thoracic Transplantation. The authors will discuss subjects related to pediatric lung transplantation such as access to donor organs, allograft dysfunction and role of functional status in outcomes.

Rates Of, Reasons For, And Reactions To Discontinuation Of Glp-1 Receptor Agonists: A Narrative Review, Henry D Heisey, L Parker Gregg, Christopher D Verrico, Dennis T Villareal, Terri L Fletcher

Faculty, Staff and Students Publications

GLP-1RAs are increasingly used for their glucose-lowering and weight-management effects, but many patients discontinue them. In this narrative review we aim to review real-world, quantitative and qualitative GLP-1RA discontinuation, adherence, and persistence evidence as it aligns with an established conceptual framework for understanding medication adherence in noncommunicable chronic disease. Many inconsistencies exist in how discontinuation, adherence, and persistence are studied in this literature. Few qualitative studies have focused on discontinuation of GLP-1RAs. Quantitative approaches often focus on medication-related factors and more superficial aspects of socioeconomic and condition-related factors. Very few studies encompass all 5 dimensions of the medication adherence conceptual …

De Novo Complex Genomic Rearrangement Spanning 2q31.1 In A Proband With Congenital Malformations: Genotype-Phenotype Correlation And Development Of A Cgr Detection Pipeline, Katherine Helle, Jesse D Bengtsson, Mira Gandhi, Christopher M Grochowski, Ming Yin Lun, Neha Sudhir, Shalini N Jhangiani, Fritz J Sedlazeck, Seema R Lalani, Neil A Hanchard, Claudia M B Carvalho

Faculty, Staff and Students Publications

The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in-house CGR detection pipeline pairing genome sequencing (GS) structural variant calls with read-depth data revealed a de novo complex genomic rearrangement (CGR) spanning 2.7 Mb across 2q31 characterized by a series of duplications and triplications including the HOXD gene cluster. The genomic structure was assembled by applying combined methodologies including short-read and long-read GS, and optical genome mapping (OGM). This in-house …

Proteomic Signatures Of 3-Year Progression From Impaired Fasting Glucose To Diabetes: The Atherosclerosis Risk In Communities (Aric) Study, Mary R Rooney, Justin B Echouffo Tcheugui, Jingsha Chen, Keenan A Walker, Christie M Ballantyne, Eric Boerwinkle, Tanika N Kelly, Chiadi E Ndumele, James S Pankow, Morgan E Grams, Wendy S Post, Peter J Ganz, Alexis C Wood, Jerome I Rotter, Elizabeth Selvin, Josef Coresh

Faculty, Staff and Students Publications

Objective: To identify proteomic signatures underlying 3-year progression from impaired fasting glucose (IFG) to diabetes.

Research design and methods: We examined IFG progression in the Atherosclerosis Risk in Communities (ARIC) study from visit 2 (1990-1992) to visit 3 (1993-1995). We tested associations of 4,955 plasma proteins (SomaScan version 4.0) with ∼3-year progression from IFG (FG 100-125 mg/dL without diabetes) to diabetes (diagnosis, medication, or FG ≥126 mg/dL) using logistic regression models adjusted for demographics, cardiometabolic risk factors, and baseline glucose with Bonferroni correction (P < 10-5). We explored biological pathways enriched among the top proteins and calculated improvements in prediction (ΔAUC and net reclassification using 3-year risk thresholds of 6% and 15% in 80% training and 20% internal validation subsamples). We validated results in the Multi-Ethnic Study of Atherosclerosis (MESA) cohort.

Results: There were 3,786 ARIC participants with IFG (mean [SD] age 57 [6] years, 52% female, …

Ephemeral To Empowered? International Comparison Of Women’S Participation In Web Series Production, 2012–2019, Nicola Evans, Marion Mccutcheon, Emilia King, Joel Bassaget, Steinar Ellingsen

Research outputs 2022 to 2026

Women are significantly underrepresented in above-the-line roles in film and television, but anecdotal evidence suggests they are gravitating to web series. To explore this, the authors built the largest known international archive of web series released during 2012–2019 and analysed women’s participation. In the top five web series producing countries in the West, women achieved or approached parity with men in producing, directing and writing, but not cinematography. Do achievements in low-budget, transitory media count for anything? Drawing on ephemeral media scholarship, we discuss the potential of such forms to disturb entrenched patterns of gender discrimination in screen industries worldwide.

Safety And Effectiveness Of Behavioural Activation For Chronic Pain: A Protocol For A Systematic Review And Meta-Analysis Of Randomised Controlled Trials, Fangyuan Zheng, Laura Hynes, Richard J. Gray, Irene Ngune, Jacqueline Sin, Martin Jones

Research outputs 2022 to 2026

Background/Objectives: Chronic pain is a prevalent and complex condition associated with substantial physical, psychological, and social burden. Behavioural activation (BA), a structured psychological intervention originally developed for depression, may be relevant to chronic pain through its focus on reducing behavioural avoidance and increasing engagement in meaningful activities. Although BA has been applied in studies involving people with chronic pain, the safety and effectiveness of BA in this population have not been comprehensively synthesised. This systematic review and meta-analysis will examine the safety and effectiveness of BA for people with chronic pain.

Empirical Rhetorical Modeling: New Analytical Tools To Evaluate The Intensity Of Rhetoric, August Immel

English Theses & Dissertations

Since 2020, the United States has experienced a surge of incendiary rhetoric in contemporary political discourse, which exacerbates societal polarization and incites violence as evidenced by heightened politically motivated attacks. Numerous actors characterize the impetus of such violence as “extreme rhetoric.” No standard definition exists for such a term, and this gap necessitates the central research question of this dissertation, which interrogates how rhetoric can be systematically evaluated for “extremeness.” I propose that the issue of extreme rhetoric can be fruitfully examined from within the context of rhetorical theory, but instead of attempting to create a new definition of “extreme …

Enhancing Stem Education With Modeling, Simulation, And Ai Technologies: From Virtual Laboratories To Intelligent Teaching Assistants, Yiyang Li

Electrical & Computer Engineering Theses & Dissertations

Rapid advancements in modeling and simulation (M&S) and artificial intelligence (AI) present new opportunities to enhance various aspects of STEM education, from virtual laboratories that simulate physical lab environments in software to intelligent teaching assistants that provide on-demand, curriculum-aligned instructional support. Virtual laboratories offer a potential solution to the access and scalability challenges of laboratory courses by allowing students to conduct experiments without physical equipment or geographical constraints. AI-powered teaching assistants, particularly those grounded in course-specific materials, can help mitigate the instructional support gap that arises when students work independently in digital learning environments. This dissertation presents three-phase research into …

Examples And Evaluation Of Sustainability Research With Tribes, Aaron M. Canter, Sharon Hausam

Faculty Publications

This is a working paper produced as part of National Science Foundation project #2115169, “Transforming Rural-Urban Systems: Trajectories for Sustainability in the Intermountain West,” known as the “Intermountain West Transformation Network” (TN), led by the University of New Mexico with institutional partners at three additional universities in New Mexico, two in Arizona, and one each in Utah, Colorado, and Washington. The TN’s Indigenous and Tribal engagement was supported through a contract with Dr. Sharon Hausam, additional work by Aaron M. Canter, coordination with Dr. Lani Tsinnajinnie, and an Advisory Committee on Indigenous Information Needs primarily comprised of Indigenous representatives in …

The Fall Of King Arthur Of Britain In Giovanni Boccaccio’S On The Downfall Of The Famous, Christopher Berard, Morris Tichenor

Humanities Program Faculty Publications

Giovanni Boccaccio (1313–75), born in Certaldo, Tuscany, is one of the tre corone (Three Crowns) of Italian Literature. He shares this distinction with Dante Alighieri (1265–1321), about whose life and literary works he wrote treatises and delivered lectures, and Francesco Petrarch (1304–74), with whom he formed a lasting friendship (beginning in 1350). All three wrote widely acclaimed literature in the Florentine-Tuscan dialect of Italian, enabling it to become the basis for standard Italian. In addition to elevating the Italian vernacular as a literary language, they prioritized Classical Studies and were forerunners of the Italian humanist movement (c.1400–1600). Today, Boccaccio is …

Gamifying The Classroom: An Interactive Literature Curriculum, Ella Mikulecky

Undergraduate Honors Theses

This thesis highlights an interactive literature curriculum that I have created to help youth engage more deeply with classical literary works. It takes inspiration from many existing collegiate-level curricula that fuse historical simulations with literary studies and adapts those teaching methods for high-school-age students. It also utilizes a variety of different teaching philosophies, game mechanics, and literary practices to create an ideal course for fostering engagement. This thesis provides a small sample of the curriculum along with a teacher’s handbook and reports the results of a pilot program conducted in the summer of 2025.

Mamma Mia: A Study Of Catholicism, Secularization, And Their Influences On Modern Italian, Lara Zanotti

Undergraduate Honors Theses

This study explores the relationship between religion and language by examining how Catholicism and secularization have shaped modern Italian. While the historical influence of the Catholic Church on Italian is well established, less attention has been given to how recent secularizing trends have transformed the language at lexical, discursive, and sociolinguistic levels. Addressing this gap, the study asks: how have Italy’s deep-rooted Catholic traditions and its more recent shift toward secularization influenced the meanings, frequency, and use of religiously rooted expressions in modern Italian?

Using a mixed-methods approach, this project combines corpus-based linguistic analysis with qualitative analysis. Diachronic data from …

Ai-Ready Libraries Require Ai-Ready Librarians: Building Organisational Capability For Digital Transformation, Salihin Mohammed Ali

Research Collection Library

Academic libraries worldwide are rapidly experimenting with artificial intelligence (AI) to enhance research, learning, discovery, operations, and user engagement. However, many institutions continue to approach AI adoption primarily through isolated pilots, individual experimentation, or technology-centric initiatives. While these efforts generate innovation, they often struggle to scale sustainably without corresponding organisational capability development. This presentation argues that AI-ready libraries require AI-ready librarians and proposes an organisational capability approach for sustainable AI transformation in academic libraries. Drawing from the development of a library-wide AI strategy plans at Singapore Management University, the presentation explores how AI capability-building can be operationalised across diverse functional …

Business Responsibility And Sustainability In India : A Comprehensive Analysis Of Brsr Disclosures Of India’S Top 1,000 Listed Companies For Fy 2024–25, Rajeev Ranjan Tripathi, Aditya Gupta, Mohan Krishna, Sonika Gandhi

Monograph and Other Reports

The intersection of capital markets, corporate governance, and sustainable development has, over three decades, given rise to a transformative shift in management practice: the systematic disclosure and evaluation of Environmental, Social, and Governance (ESG) performance. Once confined to niche ethical investment circles, ESG reporting has evolved into a mainstream imperative, shaping investment decisions, regulatory frameworks, and stakeholder expectations across both developed and emerging economies. Today, ESG performance is no longer an addendum to financial reporting but a substantive dimension of enterprise value and long-term organisational legitimacy. India’s ESG reporting journey reflects a trajectory of incremental but decisive policy evolution. The …

"Dark And Loathsome": The Construction And Persistence Of Racial Theology In The Church Of Jesus Christ Of Latter-Day Saints, Margaret Phillips

Electronic Theses, Projects, and Dissertations

The Church of Jesus Christ of Latter-day Saints banned Black men from holding the priesthood until 1978, a policy many mistake for the whole of the faith's engagement with race. This thesis argues that the priesthood ban was only a symptom of a far deeper theology of race, one built into Mormonism's broader theology from its founding. Two intertwined beliefs anchor this theology: the default whiteness of the human body and soul, and twin curse narratives that mark Black and Indigenous peoples alike as bearers of a divine curse— dark skin read as the visible penalty for their ancestors' sin. …

Understanding College Student Expectancies Of Simultaneous Engagement In Multiple Risk Behaviors: A Measurement Development And Model Testing Study, Shelby Whalen

Electronic Theses and Dissertations

Risky behaviors, actions that may cause physical, psychological, social, or economic harm to oneself or others, are prevalent among college students. While significant research has focused on single high-risk behaviors of alcohol use, drug use, gambling, and gaming separately, students frequently engage in multiple high-risk behaviors simultaneously, such as drinking alcohol while gambling. Research shows that students have distinct and specific expectancies about what happens when they engage in a risk behavior, however, minimal research has examined students’ perceptions or reasons for simultaneous poly-risk behavior engagement. This multi-phase project characterized students’ outcome expectancies for simultaneous poly-risk behavior combinations, developed and …

Disruption, Recovery, And Divergence: How Prepandemic Achievement Levels Shaped Learning Loss, Recovery, And Spending Efficiency In Tennessee Public High Schools, Wilson Boyd

Electronic Theses and Dissertations

The COVID-19 pandemic caused significant and uneven learning loss in Tennessee public high schools. The statewide ACT composite average fell from 20.2 in 2019 to 19.1 in 2021. By 2024-2025, it recovered only to 19.3. During the same period, Tennessee received approximately $3.86 billion in additional federal funds and $1.15 billion in new state funding. This ex post facto quantitative study examined whether prepandemic achievement levels predicted learning loss severity and recovery patterns of a census of 322 Tennessee public high schools from 2018-2019 through 2024-2025.

The study used two theoretical frameworks. Baumol's cost disease theory predicted that structural productivity …

Kindergarten Aimsweb Ela Composite As A Predictor Of Third-Grade Reading Proficiency In A Rural, High-Poverty School District, Christi J. Gentry

Electronic Theses and Dissertations

Reading proficiency by the end of third grade is a critical milestone as students transition from learning to read to using reading as a tool for learning. In Tennessee, this proficiency is especially significant because promotion and retention decisions are linked to student performance on the Tennessee Comprehensive Assessment Program (TCAP) ELA assessment. This quantitative, longitudinal study examined the extent to which kindergarten readiness, operationalized as kindergarten AIMSweb ELA Composite scores, predicts third-grade reading proficiency status in one rural, high-poverty school district. Using archival student-level data, this study analyzed kindergarten AIMSweb ELA Composite scores and third-grade TCAP ELA proficiency. Logistic …

Teacher Autonomy In Accountability-Driven Contexts: A Phenomenological Study Of Middle School Mathematics Teachers In East Tennessee, Hollyann Perdue

Electronic Theses and Dissertations

The purpose of this qualitative phenomenological study was to explore East Tennessee middle school mathematics teachers’ experiences of professional autonomy and how those experiences relate to institutional decision making within the accountability-driven educational environment. This study utilized the Self-Determination Theory (Ryan & Deci, 2017) as a framework to examine how teachers perceived their ability to make instructional decisions while navigating district expectations, pacing requirements, mandated curriculum, and state testing pressures. Data were collected through one-on-one semi-structured Zoom interviews with 12 East Tennessee middle school mathematics teachers representing varying levels of teaching experience, effectiveness ratings, and instructional settings, including both general …

Weathering More Than Storms: Understanding The Mental Health Disparities Of Black Farmers In The Appalachian Region, Aliyah Smith

Electronic Theses and Dissertations

Black farmers in Appalachia represent a vital and historically marginalized population within one of America’s most economically distressed regions. Black farmers have endured generations of systemic racism, resulting in land loss, economic hardship, and mental stressors. This study examines the intersection of race, agriculture, and behavioral health to illustrate how structural barriers and cultural stigmas shape the mental well-being of Black farmers across Appalachia.

Findings from the analysis will guide the development of a conceptual model based on constructs from the Social-Ecological Model (SEM), Intersectionality Theory, and Critical Race Theory (CRT). This study will use Key Informant Interviews (KIIs) conducted …

Staff Education On The Implementation Of An Evidence-Based, Suicide-Risk-Assessment Education Program For Psychiatric Staff, Yemurai Emily Dzikiti

Walden Dissertations and Doctoral Studies

Suicide is a major public health concern, and consistent suicide risk assessment is essential for patient safety in psychiatric settings. This Doctor of Nursing Practice staff education project addressed a knowledge gap in evidence-based suicide risk assessment among psychiatric clinicians in an outpatient mental health setting. The practice-focused question examined whether an evidence-based suicide risk assessment education program would improve clinicians' knowledge from pre- to post-education. The educational intervention consisted of a 60-minute in-person training session on evidence-based suicide risk assessment using the Columbia-Suicide Severity Rating Scale (C-SSRS) and the Suicide Assessment Five-Step Evaluation and Triage (SAFE-T) framework. Ten psychiatric …

2026-2027 Lindenwood University Graduate Course Catalog, Lindenwood University

Course Catalogs

Lindenwood University Graduate Course Catalog

2026-2027 Lindenwood University Undergraduate Course Catalog, Lindenwood University

Course Catalogs

Lindenwood University Undergraduate Course Catalog

2026-08-01 Caudill Connection, Morehead State University. Caudill College Of Arts, Humanities And Social Sciences.

Caudill Connection

Caudill Connection newsletter for August of 2026.

Hyperadhesive Von Willebrand Factor Contributes To Pathogenesis Of Preeclampsia, Yajuan Wang, Chenyu Wang, Katie L Houck, Xiaoli Gao, Yuanyuan Chen, Xin Xu, Xue Zhao, Miguel A Cruz, Shu Zhang, Chester Q Li, Fengxia Xue, Min Li, Swati Shree, Jing-Fei Dong, Cha Han

Children’s Nutrition Research Center Staff Publications

Background: Preeclampsia is the most common complication of pregnancy, significantly affecting maternal and fetal health, and is characterized by placental and systemic endotheliopathy. Patients with preeclampsia have elevated levels of VWF (von Willebrand Factor), which is associated with poor clinical outcomes. However, whether VWF serves as a marker for endotheliopathy or contributes to the pathogenesis of preeclampsia remains poorly understood.

Methods: We investigated the role of hyperadhesive VWF in the development of preeclampsia by studying patients, evaluating mouse models, and performing in vitro experiments.

Results: We show that patients develop VWF- and fibrin-rich thrombosis in the placenta and have significantly …

Concerns With The Statistical Analysis In “Effect Of Combined Glp-1 Analogue And Bupropion/Naltrexone On Weight Loss: A Retrospective Cohort Study”, Thirupathi Reddy Mokalla, Henry T Robertson, Sherri Pals, David B Allison

Children’s Nutrition Research Center Staff Publications

No abstract provided.

All-Cause And Cause-Specific Mortality In Gambling Disorder: Evidence From A Nation-Wide Matched And Sibling Cohort Study In Taiwan, Yang-Chieh Brian Chen, Chih-Wei Hsu, Liang-Jen Wang, Mu-Hong Chen, Yao-Hsu Yang, Chih-Sung Liang, Edward Chia-Cheng Lai

Children’s Nutrition Research Center Staff Publications

Background and aims: Gambling disorder (GD) has been linked to suicidal ideation and suicide deaths; however, evidence on all-cause and cause-specific mortality-particularly in Asian populations-remains limited. Using a retrospective cohort study based on nationwide matched and sibling cohort, we investigated all-cause and cause-specific mortality risk in patients with GD.

Design, setting and participants: A retrospective cohort study was conducted using 2000-2022 data from Taiwan's National Health Insurance Research Database. A cohort of 961 individuals diagnosed with GD was identified. An age- and sex-matched control cohort (n = 3,844) and an unaffected sibling cohort (n = 675) were constructed. Cumulative survival …

Use Of A Task Analysis Application With Video-Prompting To Increase Social Skills For Individuals With Moderate To Severe Intellectual Disabilities, Zachary Hurley

All Dissertations

Individuals with intellectual and developmental disabilities present deficits in both intellectual functioning and adaptive behavior, which can limit an individual’s ability to function independently. Given the different levels of intellectual functioning and adaptive skills, individuals with moderate intellectual disabilities require a level of support in daily situations and environments. However, individuals with severe to profound intellectual disabilities require the most extensive amount of support in daily skills. Research demonstrates that the use of video-based instruction is an effective tool in increasing social skills among individuals with intellectual disabilities. Additionally, conclusions derived from the current review of literature identified gaps in …

An Investigation Of The Use Of Self-Regulated Strategy Development With A Mnemonic On The Fraction Computation Performance Of Students At-Risk For Emotional/Behavioral Disorders, Melissa D. Hullett

All Dissertations

Interventions that help students organize their thinking can reduce cognitive load and support academic, behavioral, and social success. Self-Regulated Strategy Development (SRSD) is an evidence-based instructional framework that combines strategy instruction with self-regulation to promote student independence and improve student confidence. A mnemonic has been shown to help scaffold support across all content areas to the level of mastery required by Stage 4 of the SRSD framework ("Memorize It"). In mathematics, where executive functioning demands are high, interventions to scaffold content must provide the metacognitive support needed for a diverse student population. This study used a multiple-baseline design to examine …

Speakin’ Southern: A Phenomenological Exploration Of The Lived Experiences Of College Students With A Southern Dialect, Michael J. Farmer

All Dissertations

Southern dialects are often stereotyped, and southern speakers are often negatively perceived.  The prejudice they may face is perpetuated by Standard Language Ideology (SLI) in which linguistic discrimination is intentionally or unintentionally perpetuated through power structures. While scholarship exists regarding southern dialectal speakers facing SLI in settings such as K-12 classrooms, the workforce, and dialectally unique communities, research into southern dialectal college students navigating the power structure of higher education is sparse. What research does exist in this space often utilizes a mixture of quantitative and qualitative methods to track linguistic variables in light of these experiences. This dissertation, however, …