Digital Commons Network^™

Optimizing Xylitol Production: A Molecular And Experimental Study Of Xylose Reductase In Candida Tropicalis, Zackery Neal

Masters Theses and Doctoral Dissertations

Xylitol, a naturally occurring sugar alcohol, is widely used in the food and pharmaceutical industries as both an artificial sweetener and an anticariogenic agent. Traditional xylitol production relies on harsh chemicals and energy-intensive processes, making microbial fermentation a more sustainable alternative. This study explores the ability of Candida tropicalis to convert D-xylose into xylitol through the enzyme xylose reductase, with a focus on optimizing pH conditions to enhance conversion efficiency. To achieve this, both experimental fermentation and computational molecular dynamics simulations using GROMACS and the pHbuilder tool are employed. By analyzing the enzyme’s stability and structural dynamics across different pH …

Dna Methylation Markers Of Insulin Resistance Surrogate Measures In The Atherosclerosis Risk In Communities (Aric) Study, Jeewoen Shin, Jan Bressler, Megan L Grove, Michael Brown, Elizabeth Selvin, James S Pankow, Myriam Fornage, Alanna C Morrison, Chloé Sarnowski

Faculty, Staff and Student Publications

Insulin resistance (IR) is a risk factor for cardiovascular diseases and type 2 diabetes. Associations between DNA methylation (DNAm) and IR have been less studied in African ancestry (AA) populations than those of European ancestry (EA). We aimed to identify associations between whole blood DNAm and IR in up to 1,811 AA and 964 EA participants from the Atherosclerosis Risk in Communities (ARIC) study. We quantified IR using three surrogate measures: the homeostasis model assessment of insulin resistance (HOMA-IR), the triglyceride-glucose index (TyG), and the triglyceride glucose-body mass index (TyG-BMI). We used ancestry-stratified linear regression models to conduct epigenome-wide association …

Voices Of Resistance: Multilingual Identity Formation Through Translanguaging In Dual Language Bilingual Education, Fernando W. Milmo

Theses and Dissertations

This qualitative case study explored how students navigated their evolving multicultural and multilingual identities in a setting with varying emphases on English and Spanish in the context of a fourth-grade dual language classroom where the teacher employed translanguaging pedagogy. This study is grounded in a theoretical framework that integrates decolonial, raciolinguistic, and translanguaging perspectives. The study examined students' perceptions of linguistic hierarchies and the ways they utilized their full linguistic repertoires to negotiate meaning, identity, and a sense of belonging. This study included pláticas as a culturally grounded narrative method, classroom observations, and interviews, and used a qualitative case study …

Deep Community Engagement: Faculty Responsiveness Perspectives At A Hispanic Serving Institution, Joseph Coppola

Theses and Dissertations

This qualitative, narrative inquiry investigates how experienced faculty members embody and enact responsive pedagogical practices at a community college Hispanic-Serving Institution (HSI). Despite generational poverty and low degree attainment among Latine students, institutions face mounting pressure from deficit-mindedness and political mandates that threaten educational equity and resources for HSIs. This research sought to answer: How do community college faculty teaching at a Hispanic Serving Institution exhibit attributes of responsiveness?

The theoretical framework utilized the core tenets of Paulo Freire’s critical pedagogy and integrated models from Gloria Ladson-Billings (culturally relevant pedagogy), Geneva Gay (culturally responsive teaching), Django Paris (culturally sustaining pedagogy), …

Hispanic Academic Leadership In The Health And Human Services, Gabriela Elizabeth Rangel

Theses and Dissertations

In the United States, there are 63.7 million Hispanics (U.S. Census Bureau, 2023), making them the largest racial or ethnic minority in the country. National data from 2019 indicates that only 6% of tenured faculty in the U.S. were Hispanic, highlighting a significant underrepresentation of leaders in academia (NCES, 2024). This study employed a phenomenological approach with purposeful sampling, utilizing semi-structured interviews with ten participants who had leadership experience in academia within Health and Human Services (H&HS). The interviews served to explore various aspects, such as what were their aspirations to become leaders, their perceptions of the characteristics and qualities …

Educators’ Perceptions Of Mental Health Services For Middle School Students In A South Texas District, Norma Araceli Cabrera

Theses and Dissertations

The purpose of this phenomenological qualitative study is to examine teachers' and administrators' perceptions of school-based mental health services in one school district in South Texas. Within-case sampling was utilized to select the participants. The study examines educators' perceptions of the availability and effectiveness of mental health services for middle school students. Middle school is a period of intense social development, during which students strive to navigate peer relationships. Middle school children, aged 12-14, also undergo emotional development as they manage intense emotions, develop self-awareness, and learn to cope with stressors related to school, friends, and self-identity. Studies found that …

Navigating Cultural And Professional Identities: A Study Of Hispanic Women's Experiences In Aerospace Internship Programs, Jennifer Becerra

Theses and Dissertations

This phenomenological study investigated how Hispanic women navigated cultural identity and professional development during National Aeronautics and Space Administration (NASA) internship programs, examining the role of culturally responsive mentoring in supporting retention. The research question was, How do Hispanic women in aerospace-internship programs navigate the intersection of cultural identity and professional development as they transition from academic science, technology, engineering, and mathematics (STEM) programs to aerospace careers, and what role does culturally responsive mentoring play in supporting their retention?

Using Anzaldúa’s nepantla concept, Duncan-Andrade’s critical-hope theory, and Ladson-Billings’ culturally relevant pedagogy as theoretical frameworks, in this study, I employed semistructured …

Collective Agency And Community Resilience Among Farmworkers In The Lower Rio Grande Valley, Angel Velazquez

Theses and Dissertations

This research assesses how farmworkers in the Lower Rio Grande Valley of Texas use everyday practices to build resilience and adapt to changes in their lives. I apply two interconnected theories, White’s (2017, 2019) framework of collective agency and community resilience and Castro and Sen’s (2022) framework of everyday adaptation actions, to study these practices. I conducted 19 semi-structured interviews with Latino farmworkers and professionals who work with local farmworker organizations in the Rio Grande Valley (RGV) of Texas. Interview transcripts were analyzed to determine if and how Latino farmworkers in the RGV can work towards community resilience and implement …

Decolonizing The Whitexican: Reclaiming Identity Through Nahuatl And Mesoamerican Motifs, Laia Ivanna Vite Cano

Theses and Dissertations

This thesis explores the intersection of art, linguistics, and ideography through the lens of personal and cultural heritage rooted in the Huasteca region of Central Mexico. Drawing inspiration from familial connections to the pueblos of Huazalingo and Huejutla in Hidalgo, Mexico, the research examines the cultural complexities of bicultural and binational experiences. It is grounded in the theoretical framework of Nepantla, a concept introduced by Gloria Anzaldúa to describe the unseen space of the border life as one of existing between worlds, identities, and cultures. Included and essential to this work is the Coyolxauhqui Imperative, which informs the process of …

Applicability Of Cementochronology To Estimate Season-Of-Death In Humans: Insights From Modern Documented Collections, Olga Ibarra-Sanchez

Theses and Dissertations

Dental cementum is characterized by lifelong deposition of alternating opaque annuli in fall/winter and translucent bands in spring/summer. This study aims to test the applicability of cementochronology to estimate season-of-death, by observing the properties of the last layer, with direct implications for forensic anthropology and bioarchaeology. The sample includes canine teeth from 146 adults (84 males, 62 females), age-at-death ranging from 20-97 years (mean=61.7 years, SD=18.6 years), from two contemporary skeletal collections. Of these individuals, 78 (53.4%) died in spring/summer and 68 (46.6%) died in fall/winter. Overall accuracy was low at 64.4% (94/146). Accuracy was higher for spring/summer deaths 100.0% …

College Ready Or Not? Exploring Undergraduate Perceptions Of Their High School College Preparation, Charles M. Morgan Iii

Electronic Theses and Dissertations

The purpose of this study was to examine undergraduate students’ perceptions of their high school preparation for college. Rather than relying on institutional measures like test scores or course completion, the study focused on how students themselves described their readiness and the supports they received in high school. By highlighting student voice, the research aimed to reveal strengths and gaps in current approaches to preparing students for higher education.

The study was grounded in Educational Equity Theory (Darling-Hammond, 1997), which emphasizes that fairness in education requires supports tailored to students’ individual needs. A qualitative, phenomenological design was used. Undergraduate participants …

The Butterfly Effect: Cognitive Coachingsm As A Catalyst For Educator Learning And Lasting Change, Katie B. Givens-Martin

Electronic Theses and Dissertations

This qualitative, interpretative phenomenological analysis (IPA) research study explores instructional coaches’ perceptions of the impact of Cognitive Coaching℠ on teacher instruction, efficacy, and professional learning implementation. Findings across the four research questions reveal a cohesive perception among instructional coaches that Cognitive Coaching℠ functions as a catalyst for teacher growth, agency, and efficacy.

Coaches described their roles primarily as facilitators who guide rather than direct, emphasizing trust-building, reflection, and empowerment as essential. The findings highlight that Cognitive Coaching℠ strengthens teacher self-efficacy, which aligns with the six core principles of andragogy, with coaches observing increases in confidence, risk-taking, and professional agency. The …

Echo’S Repertoire: Performing Science Fiction And Trans Care Models, Juniper Blue

Theses

Echo’s Repertoire is a mixture of a passion piece and a call for more work with performing science fiction. It focuses on interpersonal communication within trans studies and the experiences of transgender individuals and myself. Echo’s Repertoire is also an example of the Lyrical Model proposed by Awkward-Rich as a new model for trans affirming speech. The show is laid out non-linearly and follows along with Echo as he starts to build new relationships with the advice of his spaceship ai, Eep, who is a previous version of himself prior to transformation (transition).

Building Young Leaders With Purpose: Teaching Leadership And Anti-Bullying Through Student Leadership Club, Yaned Anaya-Soto, Julyana Lopez

Capstone Projects and Master's Theses

This capstone project was developed to implement a Student Leadership Club for elementary students’ in response to high levels of bullying influenced by unmet social emotional needs, family stress and increased access to technology. The project took place at Jesse G. Sanchez Elementary School within the Alisal Union School District (AUSD). A predominantly Latino, multilingual and economically vulnerable TK- 6th school in Salinas, CA. The eight week curriculum was designed to strengthen leadership skills through self and peer nominations to help promote bullying prevention among fifth and sixth graders. Weekly meetings focused on communication, empathy and upstander behaviors. Pre and …

College Readiness Support, Emely Contreras

Capstone Projects and Master's Theses

This paper examines the College Readiness Support project implemented at Learning for Life Charter School (LFLCS), an independent charter school serving at-risk youth across Monterey, San Benito, and Santa Cruz counties. LFLCS supports students who face barriers such as poverty, homelessness, foster care, and credit deficiencies, which often result in low engagement and limited postsecondary readiness. The project was developed to address these challenges by guiding juniors and seniors through the college application process and connecting them with financial aid and scholarship resources. A key component included organizing a field trip to California State University, Monterey Bay’s Educational Opportunity Program …

Streams Guidelines: Standards For Technical Reporting In Environmental And Host-Associated Microbiome Studies, Julia M. Kelliher, Chloe Mirzayi, Sarah R. Bordenstein, Aaron Oliver, Christina A. Kellogg, Eneida L. Hatcher, Maureen Berg, Petr Baldrian, Mashael Aljumaah, Cassandra Maria Luz Miller, Christopher Mungall, Vlastimil Novak, Alexis Palucki, Ethan Smith, Nazifa Tabassum, Gregory Bonito, J. Rodney Brister, Patrick S. Chain, Mingfei Chen, Samuel Degregori, Xuefeng Peng, Et. Al.

Faculty Publications

The interdisciplinary nature of microbiome research, coupled with the generation of complex multi-omics data, makes knowledge sharing challenging. The Strengthening the Organization and Reporting of Microbiome Studies (STORMS) guidelines provide a checklist for the reporting of study information, experimental design and analytical methods within a scientific manuscript on human microbiome research. Here, in this Consensus Statement, we present the standards for technical reporting in environmental and host-associated microbiome studies (STREAMS) guidelines. The guidelines expand on STORMS and include 67 items to support the reporting and review of environmental (for example, terrestrial, aquatic, atmospheric and engineered), synthetic and non-human host-associated microbiome …

Hygiene Heroes: Strengthening Oral Hygiene To Reduce Central Line-Associated Bloodstream Infections In Pediatric Hematology/Oncology Patients, Sidney Clymer-Engelhart, Kirstie Shulman

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

Background: Central line-associated bloodstream infections (CLABSIs) impact pediatric patient outcomes, increasing mortality, hospital stays, and healthcare costs. At Sutter Medical Center Sacramento (SMCS), the CLABSI prevention bundle includes proper line care, dressing assessments, and hygiene practices, including twice-daily oral care, daily linen changes, and chlorhexidine gluconate (CHG) bathing. Sutter found their CLABSI bundle compliance at approximately 76–78%, with oral hygiene identified as the most frequent gap in care.

Aim: This quality improvement project, partnered with SMCS, targeted oral care compliance to enhance overall bundle adherence, strengthen staff-leadership communication, and ultimately reduce CLABSI rates in the hematology/oncology units. In a wider …

Fall Prevention In The Lobby Of The Emergency Department At Sutter Medical Center Sacramento, Tanya Rodriguez Duarte, Vaneza Espino, Roshni Hayer, Yajari Mendoza

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

Background: In 2024, Sutter Medical Center Sacramento (SMCS) reported 17 patient falls in the Emergency Department (ED) lobby, with 94% (n = 16) occurring in the triage area. Patients awaiting placement after triage are not classified as admitted and thus are not included in CMS’s inpatient fall reporting program. However, due to the known safety risk, SMCS ED leadership began tracking lobby falls locally and partnered with University of the Pacific nursing students to address this issue.. Aim: This quality improvement project aimed to reduce the incidence of falls in the ED lobby through enhanced fall risk identification, timely reassessment, …

Extreme Bandgap Recessed-Gate Metal Oxide Semiconductor Heterostructure Field Effect Transistors With Drain Current 0.28 A Mm−1 And Threshold Voltage −1.5 V, Abdullah Al Mamun Mazumder, Abdullah Mamun, Kenneth Stephenson, Kamal Hussain, Tariq Jamil, Grigory Simin, Asif Khan

Faculty Publications

Herein, the first demonstration of hybrid high-k oxide (ZrO2-Al2O3) incorporation into extreme bandgap (EBG) Al_0.87Ga_0.13N/Al_0.64Ga_0.36N metal-oxide-semiconductor heterostructure field-effect transistors (MOSHFETs) is presented, with both planar and recessed-gate designs on the same AlN/sapphire template with a state-of-the-art low contact resistance of 1.4 Ω mm (contact resistivity, ρc ≈ 5.7 × 10−6 Ω cm2). The recessed-gate MOSHFETs achieve a threshold voltage shift of ΔVTH = 5.8 V, highlighting improved channel control. Static output measurements reveal a peak drain current (IDS) of 340 mA mm⁻¹ for the planar …

Writing The Script: Shaping Korean National Identity, Media Imperialism And The Revolution Of K-Dramas, Isai J. Martinez

Electronic Theses, Projects, and Dissertations

This thesis explores the role of South Korean television dramas (K-dramas) as cultural artifacts that the Korean creators have created and become agents, which in turn has constructed and projected globally the modern South Korean national identity. Positioned at the crossroads of cultural imperialism, nationalism, resistance and appropriation, K-dramas have become extremely critical to reshaping South Korea’s place in the global media landscape. Through the lens of the Hallyu (The Korean Wave), this study analyzes how K-drama’s navigate an ambiguous cultural space which simultaneously resists Western media dominance while appropriating global forms including platform-based distribution, tailoring original content to …

Rise Above!! Second-Wave Post Punk/ Hardcore In Orange County, 1977-1983, Jessie Zepeda

Electronic Theses, Projects, and Dissertations

Post-punk and Hardcore played a pivotal role in creating a youth identity in Orange County that created a stark contrast to the more recognized Republican image of O.C. during the late 1970s and early 1980s. While historians view this era of California for its Republican ties with former presidents such as Ronald Reagan and Richard Nixon, we overlook the much more underground, yet important, identity created by many of the adolescents and young adults during this time. Though it is essential to recognize these Republican ties as they play a key role in understanding political dynamics and cultural studies that …

The People’S Medicine: Modern Perspectives On Folk Medicine In South Central Appalachia, Stacey M. Horton

Electronic Theses and Dissertations

The study addresses the critical need to document Appalachian folk medicine conventions and cultural practices from a modern perspective. In so doing, it addresses folk medicine research gaps in understudied places in South Central Appalachia, particularly in Southwestern Virginia and Northeast Tennessee. This research utilizes participant observation and oral history interviews to research modern Appalachian folk medicine practices among a select group of practitioners. Interviews focused on individuals who center their professional careers and subsequent lifestyles around herbalism, foraging, folk medicine, ethnobotany, and botanicals. By utilizing a critical praxis framework, the study seeks to move beyond lists of symptoms and …

Bias And The Writing Process In Adaptations And Retellings Of Mythology, Haley Sanderson

Electronic Theses and Dissertations

My thesis is an examination of how adaptations and retellings of mythology are written and affected by readership and reception of mythology. I compare American Gods by Neil Gaiman and The Penelopiad by Margaret Atwood and how they are written as adaptations and retellings of mythology. As seen in both novels, the presence of the mythological source material in adaptations and retellings of mythology is equally influenced by authors’ perception and the influence of readership. Approaching the ideological positions of Atwood and Gaiman through the similarities and differences of The Penelopiad and American Gods provides a deeper insight on the …

"That Was Something I Had To Get Used To”: Communication Challenges Of African Graduate Teaching Assistants, Mohammed Hafiz Nabila

Electronic Theses and Dissertations

This qualitative study examined the communication challenges and adaptive strategies of African Graduate Teaching Assistants (AGTAs) in U.S. higher education, focusing on East Tennessee State University. The study aimed to understand how AGTAs navigate linguistic, cultural, and institutional barriers in their teaching roles. Using semi-structured interviews with seven participants, data were analyzed through thematic analysis to identify key patterns and meanings. Findings revealed challenges related to accents, cultural adjustment, and limited institutional preparation. Faculty mentorship played a vital role in shaping AGTAs’ confidence, interpretation of challenges, and professional growth. However, lack of support often led to isolation and self-doubt. The …

Perceptions Of Choral Teachers On The Characteristics Of A Secondary Choral Program, Nathan Dale Rhea

Electronic Theses and Dissertations

The purpose of this study was to examine the perceptions of choral teachers on the characteristics of a successful secondary choral program. The study focused on the main characteristics of excellence, success, and sustainability. The literature showed that there was a significant amount of research on the music curriculum, standards, and various assessment strategies but minimal research on perceptions on the characteristics of excellence, success, and sustainability of a choral music program at the secondary level.

Data collection strategies included individual interviews of eight participants who were choral music educators. The analysis of data occurred through the lens of the …

Comparative Value Of Echocardiography Vs. Right Heart Catheterization In Heart Failure With Preserved Ejection Fraction, Nathanael Tran, Mohammad Shaar, Hussein Al-Sudani, Ramy Sedhom, Hamza Akhtar, Kevin Bryan Lo, Gregg S. Pressman

Einstein Health Papers

BACKGROUND: Echocardiography and right heart catheterization (RHC) are useful in the evaluation of heart failure with preserved ejection fraction (HFpEF). We compared the two among decompensated HFpEF patients to determine their relative value in predicting all-cause mortality and a composite of cardiovascular (CV) death and heart failure (HF) readmission at 1 year.

METHODS: One hundred seventy-eight decompensated HFpEF patients who underwent both procedures and survived to hospital discharge were retrospectively identified. Hospital records and the National Death Index were queried to determine outcomes. Echocardiographic and invasive parameters were tested for significant associations with each outcome. Additionally, three predictive models were …

Navigating Challenges In Management Of Difficult-To-Treat Chronic Rhinosinusitis With Nasal Polyps In The Greater Gulf, Osama A. Marglani, Abdul Razzak Juratli, Athari Maatouq Alwael, Ghassan Hussain Alokby

Saudi Medical Journal

ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) poses significant management challenges, particularly in treatment-resistant cases, greatly affecting patients’ quality of life. This paper provides consensus-based recommendations to guide clinicians in managing difficult-to-treat CRSwNP in the Gulf Cooperation Council (GCC) region. A modified Delphi method was used to gather expert opinions from GCC specialists through surveys and discussions, achieving consensus on 14 key statements for CRSwNP management. Key criteria identified for difficult-to-treat CRSwNP included early recurrence after surgery, comorbid atopic diseases, and frequent need for oral steroids. The importance of structured histopathology reporting and understanding inflammatory characteristics to differentiate patients with …

Interventional Study Of The Iselfie Heart Health Tool For Assessment Of Vital Signs (Heart Rate, Blood Pressure, And Oxygen Saturation) In The Kingdom Of Saudi Arabia, Abdulaziz S. Alhomod, Demah Abdulaziz Almowanes, Robert Scooter Plowman, Azhar Quddus, Hassan Mohamed, Mahmut Karakaya, Ahmed Elgebaly, Jamilah Alrahimi, Raed Alkutshan, Adel Tash

Saudi Medical Journal

ABSTRACT Objectives: To validate the diagnostic performance of the iSelfie Heart Health tool compared to standard-of-care devices, focusing on accuracy, reliability, and classification capabilities. Methods: Vital sign measurements from 579 participants were analyzed using the iSelfie tool in calibrated and non-calibrated modes. Further analyses applied the Association for the Advancement of Medical Instrumentation (AAMI) standards and criteria for cuff-based blood pressure (BP) devices. Primary endpoints included mean absolute error (MAE) and cumulative error percentages for all vital parameters. Binary and multi-class classification analyses evaluated the device’s performance to categorize hypertension grades. Results: In calibrated mode, the iSelfie tool demonstrated high …

Prevalence Of Respiratory Distress Syndrome Among Late Preterm Infants Admitted To A Neonatal Intensive Care Unit In Saudi Arabia: A Retrospective Study, Abdulmohsen K. Alswayed, Kamal Ali, Amjad O. Alharbi, Ghadah K. Alnami, Haifa M. Bindokhi

Saudi Medical Journal

ABSTRACT Objectives: The objective of this research was to identify how common Respiratory distress syndrome (RDS) is and explore related factors in late preterm infants admitted to the neonatal intensive care unit (NICU) at King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia. Methods: A retrospective cross-sectional study was conducted over 1 year (2021). Infants with a gestational age of 34 to 36 weeks were selected using a consecutive, non-probability sampling method. Clinical, neonatal, and maternal factors were analyzed to assess their impact on the prevalence of RDS in this gestational age group. Results: The majority of infants in the …

Satisfaction With The Saudi Healthcare System: Findings From The 2019 Kingdom Of Saudi Arabia World Health Survey, Ali M. Alzahrani, Holly C. Felix

Saudi Medical Journal

ABSTRACT Objectives: To provide details on patient satisfaction with the Saudi healthcare system and patient characteristics associated with satisfaction levels using nationally representative survey data. Methods: A cross-sectional secondary analysis was conducted using the Kingdom of Saudi Arabia World Health Survey (KSAWHS 2019) data, which collected information on demographics, health status, chronic conditions, and access to and use of healthcare services among Saudi adults aged ≥15 years. Descriptive statistics and logistics regression analyses were performed to identify significant predictors of satisfaction with Saudi healthcare services. Results: Between April and July 2019, 8,912 individuals completed the KSAWHS 2019 individual questionnaire. Out …