Digital Commons Network^™

Nci-Designated Cancer Centers' Policies And Practices With Regard To Alcohol And Cancer: A Call To Lead, Ernest T Hawk, Stephanie L Martch, Meghan Si, Sanjay Shete

Faculty, Staff and Student Publications

Background: Alcohol, a known carcinogen since 1988, increases risk of cancers of the mouth, pharynx, larynx, esophagus, liver, breast, and colorectum. More than one half of US adults consume alcohol whereas about two thirds are unsure whether or unaware that alcohol intake is linked to cancer risk.

Methods: Our objective was to survey awareness, beliefs, intentions, policies, practices, and goals/perceived responsibilities related to establishing/promoting actions to reduce alcohol-related cancer risks from leaders of 72 NCI-Designated Cancer Centers.

Results: Sixty-one percent responded. Forty-three percent either believed in or were uncertain about alcohol's purported health benefits. Nevertheless, 86% considered it part of …

Perspectives Of Efl Teachers Toward The Influence Of Ai Writing Tools On Students' Writing Content And Organization, Nguyen Huu Hoang

Higher Learning Research Communications

Objectives: This study investigated Vietnamese English as a foreign language (EFL) teachers’ perspectives on the influence of artificial intelligence (AI) writing tools on students’ writing content and organization, examining tool selection patterns and effectiveness relationships through a mixed-methods approach.

Methods: An exploratory sequential mixed-methods design was employed, combining semi-structured interviews and classroom observations with six EFL teachers, followed by a survey of 52 teachers from various Vietnamese universities. Data analysis integrated thematic analysis of qualitative data with correlation and regression analyses of survey responses to examine relationships between usage patterns, institutional factors, and effectiveness ratings.

Results: Teachers strategically combined multiple …

Neuromodulation In Olfactory Networks: Inferring Circuit Motifs And Predicting Behavioral Outcomes From Neural Response Changes, Yelyzaveta Bessonova

McKelvey School of Engineering Graduate Student Theses & Dissertations

Many organisms rely on olfaction to navigate their environment in response to surrounding chemical cues. Within the olfactory system, first, external signals are transduced into neural activity patterns that drive a diverse array of behavioral responses. However, sensory processing alone does not fully account for this variability. Fluctuations in neuromodulator levels are equally critical in shaping how olfactory information is encoded and translated into behavior. The goal of this dissertation is to investigate how changes in the neurochemistry within the olfactory circuit influence neural signaling and, ultimately, behavioral responses. To achieve this, I investigated how three neuromodulators: serotonin, dopamine, and …

Suvorexant For Alcohol Use Disorder And Post-Traumatic Stress Disorder: Study Protocol For A Phase Ii Randomized Clinical Trial, Lara A Ray, Steven J Nieto, Karen Miotto, Larissa Mooney, Richard Lebeau, Jin H Yoon, Joy M Schmitz, Ron Acierno, Nathaniel W Bailey, Jessica Jenkins, Jessica Vincent, Tracy Nolen, Shawn Hirsch, Alexis Williams, Scott D Lane

Faculty, Staff and Student Publications

Background: Alcohol use disorder (AUD) represents a highly prevalent, costly, and often untreated condition in the United States. Post-traumatic stress disorder (PTSD) represents a common comorbidity with AUD which worsens outcomes and decreases functional outcomes. Suvorexant (SUV) shows clear promise as a novel therapeutic candidate to treat AUD and PTSD.

Methods: This study features a promising compound (i.e., suvorexant), the application of a well-established human laboratory paradigm (i.e., alcohol cue reactivity), and a novel early efficacy laboratory model (i.e., practice quit attempt) to provide a cost/time-efficient evaluation of safety and initial efficacy of suvorexant for AUD with comorbid PTSD. Additionally, …

Proceedings From The Inaugural Conference On The Science Of Cancer Health Equity For Sexual And Gender Minority (Sgm) Communities, Charles S Kamen, Milena E Insalaco, Richard Brown, Chasity Burrows Walters, Shine Chang, Viktor Clark, Jason Domogauer, Lauren V Ghazal, Kelly Haviland, Forrest Hosea, Nelson Sanchez, Matthew B Schabath, Zul Surani, Gwendolyn P Quinn

Faculty, Staff and Student Publications

Purpose: Sexual and gender minority people (SGM) experience multiple cancer-related disparities, including higher rates of cancer risk factors, lower rates of cancer screening, higher lifetime risk of cancer, and unmet needs throughout cancer survivorship. Although many national organizations, including the National Cancer Institute (NCI) and the American Cancer Society (ACS), have emphasized the need for more cancer research among SGM communities, currently no consensus exists about the highest research priorities, promising research models, or mechanisms to support collaboration between geographically dispersed scientific teams.

Methods: To address this gap, we convened a three-day conference to focus on the "Science of Cancer …

Exploring Sex Differences In Stroke Outcomes: A Comprehensive Analysis From The Span 1 Trial, Anjali Chauhan, Eunyoung Angela Lee, Rakesh B Patel, Mariia Kumskova, Enrique C Leira, Anil Chauhan, Yanrong Shi, Suyi Cao, Raymond C Koehler, Krishnan M Dhandapani, Mohammad Badruzzaman Khan, Pradip K Kamat, Ali Arbab, David C Hess, Alison L Herman, Ligia Boisserand, Lauren H Sansing, Andreia Morais, Xuyan Jin, Sanem Aykan, Takahiko Imai, Cenk Ayata, Karisma A Nagarkatti, Jessica Lamb, Márcio A Diniz, Patrick D Lyden, Jaroslaw Aronowski, Louise D Mccullough

Faculty, Staff and Student Publications

Background: Stroke is a sexually dimorphic disease, with different risk factors, incidence, outcomes, and treatment responses in men and women. While sex differences have been documented in preclinical studies, these findings often come from single-site studies with small sample sizes and require validation across diverse research settings.

Methods: We used data from the SPAN (Stroke Preclinical Assessment Network), a randomized, placebo-controlled, blinded, multilaboratory trial, to determine if sex differences in neurological outcomes are present in preclinical stroke models. We analyzed data from 665 stroke animals treated with saline, including young mice, diet-induced obese mice, aging mice, young rats, and spontaneously …

Epidemiology Of Healthcare-Associated Ventriculitis And Meningitis (Hcavm) And Community-Acquired Meningitis/Encephalitis And Evaluation Of An Off-Label Pcr Panel For Hcavm Diagnosis, Jaime Nassur, Katarina Schnell, Christine Dolon, Laura Walters, Devin Weber, Matthew Pettengill

Department of Medicine Faculty Papers

Healthcare-associated ventriculitis and meningitis (HCAVM) is associated with high morbidity and mortality, but rapid diagnostic tests intended to cover microorganisms that typically cause HCAVM are not commercially available. We sought to evaluate the etiology of HCAVM compared to community-acquired meningitis/encephalitis (CAME) at our healthcare system, and to study the utility of repurposing a multiplex molecular panel intended for positive blood cultures for HCAVM cases. Our epidemiologic review demonstrated that HCAVM cases were primarily caused by bacteria and fungi also associated with bloodstream infections, in contrast with CAME cases, which were primarily caused by herpesviruses and Cryptococcus. Eighty-two cerebrospinal fluid …

Patient-Specific Computational Flow Simulation Reveals Adverse Hemodynamic Factors Associated With Occlusion Of Directional Branches After Fenestrated-Branched Endovascular Aneurysm Repair, Kenneth Tran, Jesse Chait, Emmanuel Tenorio, Weiguang Yang, Alison Marsden, Bernardo Mendes, Jason T Lee, Gustavo S Oderich

Faculty, Staff and Students Publications

Background: Fenestrated and branched endovascular aneurysm repair can be complicated by branch vessel occlusion in the absence of structural stenosis. We hypothesized that computational flow simulation could identify adverse hemodynamic features associated with postfenestrated and branched endovascular aneurysm repair branch occlusion.

Methods: Patients undergoing 4-vessel fenestrated and branched endovascular aneurysm repair for Extent II to IV thoracoabdominal aortic aneurysms were retrospectively reviewed. Branches that occluded without identifiable kinking or stenosis on computed tomography were included, along with an equal cohort of anatomy-matched patent controls. Patient-specific pulsatile rigid-wall simulations were performed using SimVascular with individualized geometries and boundary conditions. Abnormal time-averaged …

Victims’ Rights Or The Public’S Right To Know: Rethinking The Boundaries Of The Right Of Publicity In True Crime, Millicent F. Dye

Journal of Intellectual Property Law

Advancements in technology and the development of new online platforms have paved the way for true crime to become one of the most popular genres today. While some believe true crime content is akin to news reporting, others have raised ethical concerns and believe that victims’ identities should be protected by a right of publicity.  The key is to find a balance between protecting victims and protecting free speech. This Note explores the right of publicity laws in a select few countries and addresses the shortcomings of the current approaches. This Note asserts that certain true crime content must be …

No Patent Attorney In Their Right Mind: How Jepson Claims Clarify Subject Matter Eligibility Post-Mayo, Jared M. Brown

Journal of Intellectual Property Law

Patent practitioners have gradually shelved Jepson claims for four decades. In those four decades, Supreme Court patent subject matter eligibility jurisprudence has taken a roller-coaster ride from an ancient point-of-novelty approach through the days of Diamond v. Diehr and back to a modernized arguably point-of-novelty-focused approach again in Mayo and Alice. In the absence of congressional action, the Federal Circuit has been left to deal with the aftermath. The inventive landscape—particularly with regard to biotech and software—is shifting fast, and our patent scheme is struggling to keep up.

In the case of software inventions, the Federal Circuit has largely …

Patents In Paradise: The Evolution Of Patent Law In The Cayman Islands, Andrew W. Torrance, Andrew P. Morriss, Lisa C. Friedman

Journal of Intellectual Property Law

This study examines the Cayman Islands’ unique position in the global intellectual property (IP) landscape, contrasting its success as an exporter of financial and legal services with the inherently domestic nature of patent protection. We hypothesize that due to this limitation, the Cayman Islands functions as a strategic, cost-effective jurisdiction for augmenting patent protection initially obtained elsewhere. Our research provides the first comprehensive analysis of Caymanian patents, and through a quantitative examination of patent family data—including filing trends, economic valuation, geographic distribution, and assignee profiles—we find strong empirical evidence to support this thesis.
Our findings reveal a disproportionate presence of …

Diversifying The Curriculum: A Framework For Change Through Staff-Student Collaboration, Christa De Brun, Jenny O’Connor, Chika Dike, Emily Fleming, Mariya Lyash, Graeme Murphy

Teaching and Learning Together in Higher Education

No abstract provided.

About The Author: Gerald Callahan

Creative Nonfiction Magazine

No abstract provided.

About The Author: Carol Sanford

Creative Nonfiction Magazine

No abstract provided.

About The Author: Mara Gorman

Creative Nonfiction Magazine

No abstract provided.

A Well-Worn Hanky, Simon Pang

Creative Nonfiction Magazine

No abstract provided.

Weird Science, Michael G. Stephens

Creative Nonfiction Magazine

No abstract provided.

Science And Poetry: A View From The Divide, Alison Hawthorne Deming

Creative Nonfiction Magazine

No abstract provided.

Cover To Cover: Reviews Of New Books, Karen Rosica, Lea Simonds, Kathleen Veslany, Katie M. M. Yeomans

Creative Nonfiction Magazine

No abstract provided.

History Of My Hair, Christopher Buckley

Creative Nonfiction Magazine

No abstract provided.

Cover To Cover: Reviews Of New Books, Karen Rosica, Lea Simonds, Kathleen Veslany, Katie M. M. Yeomans

Creative Nonfiction Magazine

No abstract provided.

History Of My Hair, Christopher Buckley

Creative Nonfiction Magazine

No abstract provided.

Rapid Ascent: Rocky Mountain National Park In The Great Acceleration: 1945-Present, Mark Boxwell

Rocky Mountain National Park

A Master's Thesis asserting that wat-time technologies cheap fossil fuels, and a culture of techno-optimism—epitomized by the Mission 66 development program—helped foster a “Great Acceleration” of human alterations of Earth’s natural systems.

Rocky Mountain National Park; Institute of Arctic and Alpine Research; Roaring River; La Poudre Pass; Left-hand Reservoir; Lake Isabelle; Mount. Ida Ridge Pond.

Statement For Management: Rocky Mountain National Pak, James B. Thompson

Rocky Mountain National Park

An inventory of the Rocky Mountain National Park's condition and analysis of its problems for the calendar year of 1992. The report includes photos, charts and maps.

Mills, Enos; Mirror Lake; Harbison Ditch; Grand Ditch; Eureka Ditch; Lee, Jay; Holzwarth Ranch; Housman Ranch; Selak Ditches; Pole Creek; Elk Management; Fire Management; natural Resource management Plan; Maintenance Management System; Bear Lake; Sprague Lake; Wild Basin Ranger Station; Beaver Meadows; Alpine Visitor Center; Longs Peak; Wild Basin; Mill Creek; Bear Lake road; Fall River Road; Utility Area Historic District; Holzwarth Historic District; Timber Creek Campground; Cultural Resource Management Plan; Kawuneech Valley; Lily …

Rocky Mountain National Park's Loch Vale Watershed, Jill Barron

Rocky Mountain National Park

A News Account of the National Park Service investigation whether there is an acidic deposition problem, and how acidic deposition affects high elevation ecosystems of the Southern Rocky Mountains.

Rocky Mountain National Park; Loch Vale Watershed; Acidic Deposition;

Inspiring The Future: The Next 100 Years Of Research And Learning At Rocky Mountain National Park, Ben Bobowski

Rocky Mountain National Park

A memorandum covering adaptive management on the coming future of Rocky Mountain National Park

Rocky Mountain National Park: Historical Background Data, F. Ross Holland Jr.

Rocky Mountain National Park

A study undertaken to furnish historical background information Rocky Mountain National Park for master planning.  Includes photographs and a map.

Adams, Henry; Adams, Jane; Baker, William; Bird, Isabella; Bryan, William Jennings; Byers, William; Chubbock, Clarence; Churchill, Hiram; Colfax, Schuler; Cudahy, Edward; Darrow, Clarence; Dickinson, Anna; Estes, Joel; Estes, Milton; Evans, Griffith; Fall, Albert; Farrell, Ned; Garman, Samuel; Gaskill, L. D. C.; Godsmark, Joseph; Hague, Arnold; Hayden, F. V.; Howard, J. E.; Hughes, Charles Evans; King, Clarence; Lamb, E. J.; March, M. E.; Mather, Stephen; McKelvey, Russell; Mills, Enos; Moomaw, Jack; Nichols, George; Nugent. James; Powell, John Wesley; Rigdon, John; Roosevelt, …

Rocky Mountain Annual Reports For 1915 Through 1934, C R. Trowbridge

Rocky Mountain National Park

Annual Reports for Rocky Mountain National Park beginning with the first report in 1915 and going through 1931.

Fall River Road; Grand Lake; Bear Lake Road; Sprague's Resort; Glacier Creek; Copeland Lake; Copeland Lake Road; Sand Beach Road; Mill Creek; Beaver Creek Road; Flat Top Mountain; Mills, Enos; Darnels, D. K.; Lee, N. R.; Hutchinson, J. H.; Husted, Shepherd; Hewes, Charles; Rowand, Edward; Higby, Rogers: Edmund; Clifford; Mills, Glenn; Golden, Sidney; Higby, Harry; Dunning, Harald; Johnson, Emil; Farmers Ditch; Sprague Hotel; Bradley and Patrick Helter House; Enos Mills Shelter Cabin; A. E. Brown Shelter House;   Lyman, Wilbur;

Rocky Mountain National Park: How Might Future Warming Alter Visitation, National Park Service Of The United States

Rocky Mountain National Park

An executive report for the calendar year of 2017.

Mills, Enos; Mirror Lake; Harbison Ditch; Grand Ditch; Eureka Ditch: Lee, Jay; Holzwarth Ranch; Housman Ranch; Selak Ditches; Pole Creek; Elk Management; Fire Management; natural Resource management Plan; Maintenance Management System; Bear Lake; Sprague Lake; Wild Basin Ranger Station; Beaver Meadows; Alpine Visitor Center; Longs Peak; Wild Basin; Mill Creek; Bear Lake road; Fall River Road; Utility Area Historic District; Holzwarth Historic District; Timber Creek Campground; Cultural Resource Management Plan; Kawuneech Valley; Lily Lake; Baldpate Estates; Grand Lake Cemetery; Lawn Lake Dam; Cascade Dam; national Parks Service Acts; United States Reclamation …

The Role Of Science Through A Century Of Elk Habitat Management At Rocky Mountain National Park, Therese Johnson

Rocky Mountain National Park

A report on the  role of science through a century of Elk habitat management at Rocky Mountain National Park.

Rocky Mountain National Park; Rocky Mountain National Park Elk; Elk and Vegetation Management Plan;