Digital Commons Network^™

The Impact Of Neighborhood Socioeconomic Factors And Insurance Status On Outcomes Following Reduction Mammoplasty, Shin Heng Teresa Chan, Kelsey Van Housen, Emily Isch, Judith Monzy, Julianne Bartz, Matthew Jenkins, David Kim, Andrew Newman, Heather Mcmahon

Phase 1

Introduction: The impact of and neighborhood socioeconomic factors on surgical outcomes in reduction mammoplasty remains unclear. This study evaluated the effect of area deprivation index (ADI) and insurance status on postoperative outcomes following reduction mammoplasty.

Methods: A retrospective review of reduction mammoplasty cases was conducted at a single institution over a 7-year period. Patients ≥18 years old who underwent reduction mammoplasty for benign macromastia were included. Zip-code linked ADI, insurance type, and postoperative complication rate were assessed.

Results: In total, 594 patients were analyzed. Mean age was 36.2 ± 13.1 years, mean body mass index (BMI) was 32.6 ± 5.2 …

Maternal Perceptions Of Group Well Child Care For Mothers With Opioid Use Disorder, Regan King, Taylor Carrubba, Erica Sood, Meghan Gannon, Vanessa Short, Neera Goyal

Phase 1

Introduction/Purpose: Routine well child care (WCC) is critical for monitoring growth, development, and family wellbeing. Children born to mothers with opioid use disorder are less likely to receive adequate WCC, contributing to preventable health disparities. A Philadelphia-based substance use treatment program provides comprehensive care for pregnant and parenting individuals with substance use disorders, including an on-site pilot group- based WCC model designed to enhance access to and quality of WCC.

Methods: As part of a larger cluster-randomized controlled trial comparing traditional WCC with the group WCC model, qualitative interviews were conducted with ten mothers who completed three or more group …

Analysis Of Predictive Variables For Atrial Fibrillation Detection In Patients With Cryptogenic Stroke, Paranshu Shah, Cindy Fang, Avinash Saraiya, Behzad Pavri

Phase 1

Introduction: Underlying atrial fibrillation (AF) is commonly screened for in patients with stroke of unknown cause, cryptogenic stroke (CS), using implantable loop recorders (ILRs). However, the risk factors correlated with AF detection after CS are poorly identified. Thus our goals were to elucidate which characteristics correlate with AF detection in patients with CS and to investigate if there is an age below which ILR implantation is clinically irrelevant.

Methods: We conducted a retrospective cohort study on patients with CS who underwent ILR implantation at TJUH from 4/2019-4/2021 (n=282). Exclusion criteria were < 6 months of follow-up data, ILR placement >1 year after CS, or pre-existing AF (n=64). Demographics …

Evaluation Of Clinical Outcomes Following Conventional And Hypofractionated Radiotherapy In Who Grade I Meningiomas: A Single Institution Retrospective Cohort Analysis, Toren Ikea-Mario, Wenyin Shi

Phase 1

Background: Meningiomas are the most common primary intracranial tumors. WHO Grade I meningiomas are considered benign and demonstrate high radiosensitivity, with excellent outcomes following conventionally fractionated radiotherapy (CFRT) or hypofractionated stereotactic radiotherapy (hSRT). Despite widespread clinical adoption of both approaches, direct comparative data assessing local control (LC) remain limited. This study aims to evaluate the relative efficacy of CFRT and hSRT to better inform optimal regimen selection for patients with Grade I meningioma.

Methods: We conducted a retrospective review of patients with Grade I meningiomas treated with RT at Thomas Jefferson University Hospital. Eligible patients received CFRT (2015 - 2025) …

Temporal Trends In Orthopaedic Residency Applicant Publications, Joseph Kelly, Jarod Olson, Jonathan Dalton, William A. Green, Mitchell K. Ng, Adam Fano, Robert J. Oris, Joydeep Baidya, Rachel Huang, Chloe Herczeg, Keyur Patel, Griffin White, Nikhil Sai, Alan S. Hilibrand, Alex R. Vaccaro, Christopher K. Kepler, Gregory D. Schroeder

Phase 1

Introduction/Purpose: Orthopaedic surgery is among the most competitive residency specialties, and applicants have historically relied on USMLE Step 1 scores as a metric of ability for applications. However, as Step 1 has transitioned to pass/fail in 2022, there has been a shift in emphasis toward other metrics such as research productivity. The purpose of this project is to evaluate the research trends among orthopaedic residency applicants over time with the hypothesis that post-pass/fail Step 1 applications would demonstrate higher research output at the time of application.

Methods: Residents from the top 30 orthopaedic residencies (PGY-5=211, PGY-3=211, PGY-1=213) were included. PubMed …

The Relationship Between Disease-Modifying Therapy And Quality Of Life For People Living With Sickle Cell Disease, Lana King, Sophie Lanzkron

Phase 1

Introduction/Purpose: Despite the availability of disease-modifying therapies (DMT), adults with sickle cell disease (SCD) experience a multitude of adverse health effects that impact quality of life (QOL), with pain being the most common complication. There are few studies that objectively assess the relationship between DMT use and QOL in adults. This study aims to understand whether the currently used tools are sensitive to the use of DMT.

Methods: Data included 141 adult patients from three institutions in a national sickle cell disease registry (GRNDaD). A validated questionnaire, specific for patients with SCD (ASCQ-Me), was used to assess QOL in 5 …

A Retrospective Analysis On Oxygen Therapy And Adverse Outcomes, Matthew Marhefka, Brian Schonewald,, Ross Summer

Phase 1

Introduction/Purpose: Oxygen therapy is widely utilized for cases of hypoxemia. However, limited data evaluate the adverse effects of oxygen therapy in large cohorts. We hypothesize oxygen therapy correlates to an increased rate of trips, falls, and fractures, potentially due to limited mobility and the oxygen tubing posing a hazard.

Methods: TriNetX, a deidentified electronic health record database, was utilized to create two cohorts. Both cohorts consisted of patients with a COPD diagnosis, validated with PFTs. One group had the criterion of “dependence on supplemental oxygen,” while the other group had it excluded. In order to have more balanced cohorts, both …

Identification Of Socioeconomic And Demographic Predictors Of Somatic Genomic Testing Rates In Prostate Cancer, Erin Welch, Kevin K. Zarrabi, Khaldoun Hamade, Christopher Mcnair

Phase 1

Introduction/Purpose: Somatic genomic testing in metastatic prostate cancer (mPC) identifies genomic variants which provide clinical insight into the disease biology. Somatic testing results determine eligibility for standard of care targeted therapies and clinical trial eligibility. While national guidelines recommend testing for all mPC patients, patients with adverse social determinants of health (SDOH), racial minority groups and patients with low socioeconomic status (SES) have historically undergone lower rates of testing compared to national standards. This study aims to identify barriers to testing in mPC patients in the Jefferson system and ultimately understand the factors that influence testing rates.

Methods: Epic’s clinical …

Reproducibility Of Spatially-Defined Structural Cluster Analysis Using Automated Superpixel Metrics On Swept-Source Optical Coherence Tomography, Sahil Shah, Fabio Lavinsky, Bo Young Kim, Darron King, Ronald Zambrano, Fernanda Mari Fujihara, Dilru Amarasekera, Lauren E. Hock, Ping Huang, Natasha Kolomeyer, Reza Razeghinejad, Jonathan Myers, Gadi Wollstein, Joel Schuman

Phase 1

INTRODUCTION: Optical Coherence Tomography (OCT) is essential to detect and monitor structural damage in glaucoma. However, current practices focus on global and sectoral values, not localized changes. The study explores a novel approach using spatially determined superpixel clusters from swept- source OCT (SS-OCT) to assess localized changes in both healthy and glaucomatous eyes. We hypothesize that this method will provide reproducible results comparable with standard OCT parameters.

METHODS: Healthy and glaucoma subjects with ≥ 2 qualified same-visit optic nerve head (ONH) and macular Triton SS-OCT scans were included. Automated segmentation generated superpixel thickness values from 3D disc and macula arrays. …

Effects Of A Student-Delivered Glycemic Load Education Program (Jeffgl) On Depression, Emily La, Cindy Cheng

Phase 1

Introduction/Purpose: Previous studies have demonstrated that diabetes is linked to mental health disorders, including depression. In our student-delivered education program, Jefferson Glycemic Load (JeffGL), we aim to investigate the effects of glycemic load patient education on depression in diabetic and prediabetic patients. We hypothesize that participants will demonstrate reduced depression scores compared to baseline, measured using the Patient Health Questionnaire-9 (PHQ-9), after participation in JeffGL.

Methods: Over four weeks with long-term follow up, thirty overweight or obese patients with prediabetes or diabetes recruited from Jefferson’s Department of Family Medicine will participate in one-on-one and group Zoom sessions weekly concerning topics …

The Second Amendment Right To Bear Arms, Or Lack Thereof: Assessing The Prohibition Of Unlawful Immigrants From Possessing Firearms, Anna Egensperger

Et Cetera

This Note looks at the hot button issue of whether unlawful immigrants should have the constitutional right to bear arms. Thus far, the Circuit Courts have come to different conclusions which require the input of the United States Supreme Court. Although intertwined with political views, this Note attempts to take a non-partisan stance which prioritizes the application of case law and a consistent reading of the Constitution. To provide the full context of this issue, this Note begins by describing the facts and holding of Columbia v. Heller which creates the first test for establishing a right protected under the …

Evaluating The Residential Lead Remediation Program In The City Of Lancaster, Kaitlin Mcgowan, Divine Oludi, Harriet Okatch

Phase 1

Introduction: Residential lead remediation is an effective primary prevention approach for addressing lead exposure. Current guidelines require residents of a home get relocated during the remediation. Relocation is often for a period of ten days; however, no study has explored the effect of relocation on families. This study aims to understand the experiences of relocated families with a goal to develop a framework for relocation informed by the experiences of previously relocated families.

Methods. Ten semi-structured interviews were conducted with individuals from the city of Lancaster whose homes had been remediated during the last two years. Participants described their …

High-Quality Mouse Reference Genomes Reveal The Structural Complexity Of The Murine Protein-Coding Landscape., Mohab Helmy, Jin U Li, Xinyu F Yan, Rachel K Meade, Elizabeth Anderson, Patrick B Chen, Anne M Czechanski, Tomás Di Domenico, Jonathan Flint, Erik Garrison, Marco T P Gontijo, Andrea Guarracino, Leanne Haggerty, Edith Heard, Kerstin Howe, Narendra Meena, Fergal J Martin, Eric A Miska, Isabell Rall, Navin B Ramakrishna, Alexandra Sapetschnig, Swati Sinha, Diandian Sun, Francesca F Tricomi, Runjia Qu, Jonathan M D Wood, Tianzhen Wu, Dian J Zhou, Laura G Reinholdt, David J Adams, Clare M Smith, Jingtao Lilue, Thomas M Keane

Faculty Research 2026

We present a collection of 17 high-quality long-read inbred mouse strain genomes with complete annotation (contig N50s of 0.8-33.9 Mbp). This collection includes 12 widely used classical laboratory strains and 5 wild-derived strains. We have resolved previously incomplete genomic regions, including the major histocompatibility complex (MHC), defensin cluster, T cell receptor, and Ly49 complexes. Hundreds of non-reference genes from previous publications not found in GRCm39, such as Defa1, Raet1a, and Klra20 (Ly49T), were localized in the new reference genomes. We conducted a genome-wide scan of variable number tandem repeats (VNTRs) within the coding regions, identifying over 400 genes with VNTR …

Authentication Of Art, Herbert I. Lazerow

Cleveland State Law Review

The authentication of items permeates our law and our markets. While it is important for many consumer goods, authentication is crucial for artworks and artifacts where the value difference between the authentic and the inauthentic is huge. The question is raised most frequently in conflicts between buyer and seller of art where it is claimed that a warranty was breached, or between the owner of artwork and an authenticator where the claim sounds in tort. It also arises in any situation where the value of the art is important, such as tax or antitrust. Authentication of artwork can be difficult …

Asian Reference Values For Handgrip Strength, Gait Speed, Five-Times-Sit-To-Stand Test, Muscle Mass And Calf Circumference, Jozo Grgic, Siew Ling Tey, Dieu Thi Huynh, Yen Ling Low, Zeljko Pedisic, Nina Schaller, Vanessa Kristina Wazny, Weilan Wang, Yasuhiko Saito, Ravindra P. Rannan-Eliya, Hala Ghattas Ph.D., Monique Chaaya, Carlos Mendes De Leon, Preeti Gupta, Ecosse L. Lamoureux, Mythily Subramaniam, Edimansyah Abdin, Rahul Malhotra, Angelique Chan, Bayasgalan Tumenbayar, Et. Al.

Faculty Publications

Background:

Handgrip strength, gait speed, Five-Times-Sit-to-Stand Test (FTSST) performance, skeletal muscle mass and calf circumference are important health outcomes, particularly useful for diagnosing sarcopenia. The aim of this study was to establish reference (normative) values for handgrip strength, gait speed, FTSST performance, skeletal muscle mass and calf circumference by pooling individual participant data from national cohorts in Asia.

Methods:

We conducted a pooled analysis of individual participant data from 20 national cohorts representing 12 Asian countries (China, India, Indonesia, Israel, Japan, Lebanon, Malaysia, Mongolia, Philippines, Republic of Korea, Singapore and Sri Lanka). We included cohorts with data on at least …

Uav-Deployable Open-Source Sensor Nodes For Spatial And Temporal In Situ Water Quality Monitoring And Mapping, Matthew Burnett, Mohamed Abdelwahab, Joud N. Satme, Austin Downey, Gabriel Barahona Smith, Antonio Fonce, Jasim Imran

Faculty Publications

Cost efficient, spatially resolved water quality monitoring is essential for managing pollution and protecting aquatic ecosystems. This study presents a low-cost (approximately USD 200), open-source, unmanned aerial vehicle (UAV)-deployable in situ sensor node for real-time assessment of surface-water conditions. The system integrates sensors for pH, turbidity, temperature, and total dissolved solids (TDSs), with onboard data logging and real-time clock (RTC) synchronization. Bench validation of the sensor package yielded mean absolute percentage errors of 1.34% for pH, 5.23% for TDS, and 0.81% for temperature, and the device operated continuously for 42 h. Field deployment demonstrated its ability to resolve spatial gradients, …

Staff Education On Preventing Benzodiazepines Related Falls In Older Adults, Dafnee Gilles

Walden Dissertations and Doctoral Studies

In geriatric psychiatric setting, falls rates are higher than general wards and could reach up to 13-25 falls per 1000 hospital days. High use of benzodiazepines in older adults is a major cause of increased falls despite recommendations to avoid its prescription to the population. This DNP staff education project focused on training nurses working in an 80 bed capacity geriatric psychiatric facility on best evidence based practice of preventing falls associated with use of BZDs. The identified practice issue was knowledge deficit on evidence based best practices to prevent falls in older adults under BZDs medications. The project aims …

A Taxonomic Overview Of The Apodemia Mormo Complex From A Genomic Perspective, Jing Zhang, Qian Cong, Jinhui Shen, Leina Song, Nick V. Grishin

The Taxonomic Report of the International Lepidoptera Survey

Genomic analysis of the Apodemia mormo group (Riodinidae Grote, 1895 (1827)) specimens across the range from southwestern Canada through much of the western USA and northwestern Mexico, complemented by phenotypic examination and photographs of live individuals to inspect eye color, partitions the complex into eight species, one of which is proposed as new: Apodemia (Apodemia) apache Grishin, sp. n. (type locality in USA: Arizona, Apache Co.), and three elevated from subspecies of A. mejicanus: Apodemia (Apodemia) maxima (Weeks, 1891), stat. rest., Apodemia (Apodemia) deserti W. Barnes & McDunnough, 1918, stat. nov., and Apodemia ( …

A Matter Of Detail: An Interview With Andrew Brandel, Sandra Laugier, And Perig Pitrou, Andrew Brandel, Sandra Laugier, Perig Pitrou, Gloria Fall, Tomas De Oliveira, Anna Wood, Maddalena Canna

Transatlantic Forum

This interview centers on A Matter of Detail, a collaborative volume that brings anthropology and philosophy into conversation through a shared concern with the concept and practice of detailing. Structured in three movements, the discussion begins with broad, conceptual questions about the aims of the book, including its refusal of a teleological and Eurocentric history of “detail” and its proposal to approach detail not as a fixed object but as a dynamic mode of attention. The editors reflect on how detailing operates across disciplines, not as the accumulation of facts, but as a way of articulating what matters and to …

February 11, 2026, Bcac

Booth Collaborative Advisory Committee Minutes

No abstract provided.

Rewriting Betrayal: The Political Memory Of Andrei Vlasov And His Russian Liberation Army, Christian N. Adams

Departmental Honors & Graduate Capstone Projects

This study examines the evolving historiography of Andrei Vlasov and the Russian Liberation Army (ROA) from the end of World War II to the post-Soviet era. Drawing on Soviet, émigré, and Western sources, it traces how interpretations of Vlasov’s defection reflected shifting moral and political frameworks in Russia’s collective memory. The analysis demonstrates that portrayals of Vlasov, from Stalinist condemnations to post-Soviet reappraisals, mirror the state’s changing relationship to patriotism, legitimacy, and dissent. By comparing Cold War scholarship with contemporary Russian debates, this paper argues that the Vlasov question endures not because of mere intrigue, but because it embodies the …

The Second Amendment, Illegal Aliens, And The Bruen Test: Defending The Constitutionality Of 18 U.S.C. § 922(G)(5), Ian Duncan

Cleveland State Law Review

This Note examines the constitutionality of 18 U.S.C. § 922(g)(5), which prohibits unlawful aliens from possessing firearms, under the Supreme Court’s text-and-history framework announced in New York State Rifle & Pistol Ass’n, Inc. v. Bruen and developed further in United States v. Rahimi. In the wake of Bruen, lower courts have fractured over how strictly to demand historical analogues and how to treat longstanding status-based restrictions in § 922, including prohibitions on possession by felons, domestic-violence offenders, and noncitizens. Against that backdrop, this Note argues that § 922(g)(5) is constitutionally sound.

Part I traces the development of Second …

Trauma-Informed Care In Graduate Nursing Education: A Scoping Review, Keziah Smallhouse, Stephen Didonato, Phd, Lpc

Phase 1

Introduction
Trauma-Informed Care (TIC) is a holistic, organizational framework that recognizes the widespread impact of trauma and emphasizes creating safe, supportive, and empowering environments. There is a lack of standardized and evidence-based approaches for delivering TIC education in graduate nursing programs. This project aims to examine current practices and enhance the delivery of TIC education for nursing students.

Methods
A scoping review was conducted to map the existing literature on trauma-informed nursing education in higher education settings. The review followed PRISMA-ScR guidelines, with study screening and management using Covidence. Eligible studies described higher education and included nursing students or faculty, …

Editorial: Unveiling The Next Generation Of Cancer Immunity & Immunotherapy, Mohanraj Sadasivam, Nethaji Muniraj, Chellappagounder Thangavel

Center for Translational Medicine Faculty Papers

[This corrects the article DOI: 10.3389/fimmu.2025.1769324.].

Impact Of Type 2 Diabetes Mellitus Without Retinopathy On Longitudinal Oct And Visual Field Changes In Primary Open-Angle Glaucoma, Amer Ahmed, Deena Shefter, Fabio Lavinsky, Ronald Zambrano, Qiang (Ed) Zhang, Dilru Amarasekera, Lauren E. Hock, Ping Huang, Natasha Kolomeyer, Reza Razeghinejad, Jonathan S. Myers, Gadi Wollstein, Joel S. Schuman

Phase 1

Introduction/Purpose: Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness, and diabetes mellitus (DM) is common in this population. However, the effect of DM without diabetic retinopathy (DR) on glaucoma progression is unclear. We evaluated whether structural and functional progression differ between POAG eyes with DM, but no DR, and age- and visual field (VF) mean deviation (MD)-matched non-diabetic POAG eyes.

Methods: We conducted a retrospective longitudinal study at three academic centers comparing POAG+DM (no DR) with POAG-only eyes. Eligibility required ≥3 qualified OCT scans and ≥3 reliable VFs over ≥1 year; eyes with DR or other major …

Age-Related Challenges Of Blood Pressure Management In Patients With Spinal Cord Injury, Brian Frost, Maclain Capron, Michael Stillman

Phase 1

Introduction/Purpose: Autonomic dysreflexia (AD), orthostatic hypotension (OH), and postprandial hypotension (PPH) are forms of dysautonomia that can affect people with spinal cord injury (SCI). Life expectancy for individuals with SCI has increased in recent decades, so it is critical to understand how triggers of these conditions change throughout the lifespan. This study will answer the question “What challenges do patients with SCI face regarding autonomic dysfunction as they age, and what are their perceptions of these challenges?”

Methods: This survey-based study aims to better understand dysautonomia in order to educate the medical community about specific challenges of growing older with …

Quantifying The Delay In Treatment For Patients With Newly Diagnosed Breast Cancer, Rosemary Kaufman, Meghan Maceyko, Kelsey Van Housen, Mariah Bloomfield, Scott Koeneman, Allison Doermann, Melissa Lazar

Phase 1

Introduction/Purpose: Current American Society of Breast Surgeons guidelines recommend screening or diagnostic MRI for newly diagnosed breast cancer in high-risk patients but provide no lower threshold for use. Several studies show limited benefit of preoperative MRI (pMRI), leading to inconsistent practices. As pMRI ordering increases at our institution, we aimed to evaluate the frequency of contralateral findings on pMRI and its impact on time to treatment in newly diagnosed breast cancer patients.

Methods: This retrospective review analyzed 1,580 patients with a BIRADS-6 diagnosis between 2020–2025 within the Jefferson system. The intervention group included patients who underwent pMRI after diagnosis and …

The Impact Of Icare Home Tonometry On Glaucoma Management: A Retrospective Observational Study, Irene P. Kim, Natasha Nayak Kolomeyer, Jonathan Myers, Reza Razeghinejad

Phase 1

Introduction/Purpose: Home intraocular pressure (IOP) monitoring helps detect elevated IOPs that may be missed during routine office visits for glaucoma. This study examined whether home IOP tonometry provides additional information that changes glaucoma management.

Methods: This study included 82 eyes from 46 patients examined by the Wills Eye Glaucoma Service that had iCare HOME tonometry done between 2020 to 2023. Patient demographic data, prior surgical interventions and medications, and management changes following home tonometry were collected. iCare HOME tonometry data and the presence of IOP spikes were also recorded. Physician interpretations of optical coherence tomography imaging and visual field testing …

Maternal Microchimerism In Cord Blood Of Neonates With Hypoxic-Ischemic Encephalopathy, Saniya Lakhiani, Elizabeth Wright-Jin

Phase 1

Hypoxic-ischemic encephalopathy (HIE) affects three million neonates every year, often leading to conditions including cerebral palsy, epilepsy, and motor or cognitive deficits. A risk factor for neonatal HIE is maternal inflammation; however, little is known about the mechanism behind this. Maternal inflammation may increase maternal microchimerism, maternal cells that enter the fetal compartment. Maternal microchimerism may change fetal inflammatory pathways, organ repair, and immune system development. We hypothesized that patients with HIE have a greater percentage of maternal cells in their cord blood or circulating postnatal blood than those without HIE. To test this hypothesis, fetal cord blood or early …

The Impact Of Follow-Up Visits For Pediatric Patients Readmitted With Asthma, Keerti Mallur, Talia Gillespie, Kanika Gupta, Adil Solaiman

Phase 1

Introduction/Purpose: Asthma is a leading cause of hospital admissions in pediatric patients. In addition, kids may end up readmitted to the hospital after being discharged. This negatively affects the quality of life and health of children in our country, while also placing stress on the healthcare system. Follow-up visits may improve asthma management, therefore reducing readmissions. We aim to elucidate a potential relationship between short-term readmissions and follow-up visits in pediatric patients readmitted with asthma.

Methods: This is a retrospective chart review of 128 patients at Nemours Children’s Hospital from Jan 2020 to Oct 2024 who were initially admitted with …