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The Dilemma Of Disposition Assessment: An Exploration Of Teacher Candidate Perception, Joyce Shanks, Pamela Wash, Judy Beck Mar 2026

The Dilemma Of Disposition Assessment: An Exploration Of Teacher Candidate Perception, Joyce Shanks, Pamela Wash, Judy Beck

Teacher Education Journal of South Carolina

This paper presents research on how one teacher education program is assessing dispositions. Data instruments include teacher candidate self assessment, cooperating teacher assessment, and teacher candidate questionnaires. Results indicate that teacher candidates assess themselves lower than their cooperating teachers though they think the field experiences help develop their dispositions.


Full Issue: Volume 1, 2008, Christopher Burkett Mar 2026

Full Issue: Volume 1, 2008, Christopher Burkett

Teacher Education Journal of South Carolina

This file contains the full issue of TEJSC, including front matter, table of contents, editorial notes, and articles.


Using A Patient Reference Guide To Improve Oas Cahps Scores In Endoscopy, Marijoyce Dimatulac Mar 2026

Using A Patient Reference Guide To Improve Oas Cahps Scores In Endoscopy, Marijoyce Dimatulac

Providence Nursing Research Conference 2023 – Present

No abstract provided.


The Nexus Between Perceived And Scientific Weather Patterns And Its Effects On Cereal Crop Production In Manyoni District, Tanzania, Fadhili Lufunyo Ngajilo, Helena Elias Myeya, Evarist Fundisha Swai Mar 2026

The Nexus Between Perceived And Scientific Weather Patterns And Its Effects On Cereal Crop Production In Manyoni District, Tanzania, Fadhili Lufunyo Ngajilo, Helena Elias Myeya, Evarist Fundisha Swai

Journal of Humanities and Social Sciences

This study examines the nexus between perceived and scientific weather patterns, and its effects on cereal crop production in Manyoni District; and involved 157 participants. Both quantitative and qualitative data were collected through a mixed methods research approach. The data were collected through a household survey, FGDs, in-depth interviews and documentary review methods for triangulation and complementarity purposes. The quantitative data were analysed through descriptive and inferential statistics with IBM SPSS (version 27) and Microsoft Excel Office (version 2007). The results indicate that smallholder farmers perceived that rainfall had been fluctuating with increasing trends, while temperature and wind had been …


Analysis Of Traditional Wisdom For Ecological Sustainability In Tanzania: A Case Study Of Metaphorical Source Domains In Pangwa Ritual Texts, Winne Stephen Mtega, Angelus Mnenuka Mar 2026

Analysis Of Traditional Wisdom For Ecological Sustainability In Tanzania: A Case Study Of Metaphorical Source Domains In Pangwa Ritual Texts, Winne Stephen Mtega, Angelus Mnenuka

Journal of Humanities and Social Sciences

Campaigns for ecological sustainability have gained a great currency in the contemporary academic discourse. Nonetheless, from time immemorial, Africans have pushed the ecological sustainability agenda through cultural taboos and regulated resource harvesting. Many African societies have embedded ecological consciousness in daily life expressions, and have intricately expressed it through literary and ritual texts. This study focuses on ecological awareness in the ritual texts of the Pangwa community. It analyses how environmental domains—such as land, seeds, and fruits—serve as the basis for metaphors in the Pangwa community to prove the use of wisdom to promote and sustain ecological practices (ecocriticism). The …


Ecomusicological Representation Of Climate Change And Environmental Sustainability In Selected Bongo Fleva Lyrics In Tanzania, Auson N. Wincheslaus Mar 2026

Ecomusicological Representation Of Climate Change And Environmental Sustainability In Selected Bongo Fleva Lyrics In Tanzania, Auson N. Wincheslaus

Journal of Humanities and Social Sciences

This article critically explores how Bongo Fleva’s lyrics engage with environmental themes; and the interrelationship between nature and culture in the context of the Anthropocene. The data were purposively sampled from YouTube via content analysis, from which 50 Bongo Fleva songs were listened to, and only 10 environmentally-themed songs were analysed. Then, the selected songs were subjected to transcription (from oral to written form), translation (from Kiswahili into English), and close reading and textual analysis. The close reading of the selected songs focused on the employed aesthetic and rhetorical strategies, such as anthropomorphism, symbolism, antithesis, apocalyptic tones, solastalgia, rhetorical questions, …


Climate Change Vulnerability And Adaptation Pathways: Stakeholders’ Synergies In Building Climate Resilience In The Semi-Arid Area Of Central Tanzania, Helena Elias Myeya Mar 2026

Climate Change Vulnerability And Adaptation Pathways: Stakeholders’ Synergies In Building Climate Resilience In The Semi-Arid Area Of Central Tanzania, Helena Elias Myeya

Journal of Humanities and Social Sciences

This article examines the perceived effect of climate change on cereal crop production and the responses of various stakeholders aimed at enhancing the resilience of smallholder farmers in semi-arid areas of central Tanzania. A total of 366 household heads, 28 participants in focus group discussions (FGDs), and 8 key informants from Bahi and Kongwa districts in Dodoma, Tanzania, were involved in this study. Both quantitative and qualitative data were gathered through a structured interview schedule, FGDs, in-depth interviews, and documentary reviews. Descriptive statistics and content analysis were used to analyse quantitative and qualitative data, respectively. The findings indicate that smallholder …


Cesarean Births Among Non-Us Born Hispanic Women: A Qualitative Study, Christopher Arzadon, Cecilia Bustamante-Pixa, Wally Mijangos, Linda Presson Mar 2026

Cesarean Births Among Non-Us Born Hispanic Women: A Qualitative Study, Christopher Arzadon, Cecilia Bustamante-Pixa, Wally Mijangos, Linda Presson

Providence Nursing Research Conference 2023 – Present

No abstract provided.


Lost In Translation? Bilingual Readability In Healthcare Forms, Darin Challacombe, Elizabeth Mcelhiney Mar 2026

Lost In Translation? Bilingual Readability In Healthcare Forms, Darin Challacombe, Elizabeth Mcelhiney

SACAD: Scholarly Activities

Health information achieves impact only when it is accessible and understandable to patients and their caregivers. Challacombe and McElhiney (2025), in Advances in Health Information Science and Practice, reported results from three studies analyzing the readability of patient-facing forms from the 150 highest-ranked hospitals in the United States. Their findings revealed the average readability of these forms exceeded the recommended 8th-grade reading level, indicating patients may not have fully understood their privacy rights or the specific documents requested.

This follow-up study extends the previous research by evaluating Spanish-language versions of these forms. Preliminary results suggest many translated documents are written …


Doc 2026-08 Proposal To Rename The Department Of Religious Studies To The Department Of Theology And Religious Studies, University Of Dayton. Department Of Religious Studies Mar 2026

Doc 2026-08 Proposal To Rename The Department Of Religious Studies To The Department Of Theology And Religious Studies, University Of Dayton. Department Of Religious Studies

Senate Documents

This proposal outlines the initiative to rename the University of Dayton’s Department of Religious Studies to the Department of Theology and Religious Studies to better reflect the modern academic and public distinction between the two fields. While "religious studies" is now widely understood as a secular, third-person analysis of religion, "theology" refers to the insider study of a faith tradition, which directly aligns with the department's faculty expertise and its explicitly theological MA and PhD programs. Because prospective students and local faith communities increasingly associate the term "religious studies" with purely secular education, the department has faced enrollment losses from …


Introduction, Sean Ferrier-Watson, George Neal Mar 2026

Introduction, Sean Ferrier-Watson, George Neal

Forces

No abstract provided.


Teacher Retention Across Contexts: Examining Teacher Workforce Stability And Its Impact On Student Outcomes In Traditional Public And Charter Schools In New Jersey, Telia Bennett Mar 2026

Teacher Retention Across Contexts: Examining Teacher Workforce Stability And Its Impact On Student Outcomes In Traditional Public And Charter Schools In New Jersey, Telia Bennett

Seton Hall University Dissertations and Theses (ETDs)

Teacher retention remains a critical factor in understanding disparities in student outcomes across school systems. This study examines the relationship between four-year teacher retention and student outcomes in New Jersey, with particular attention to differences between traditional public schools and charter schools. The study includes approximately 4,003 district-level observations across 670 school systems and includes six years of data (2018–2019 through 2023–2024) from the New Jersey School Performance Reports,

Findings indicate that higher rates of four-year teacher retention are generally associated with improved ELA proficiency and lower rates of chronic absenteeism, although the strength and statistical significance of these relationships …


Ionic Liquid Pilocarpine Serves As Therapeutic Cosolvent And Permeation Enhancer For Glaucoma Medication, Ashish Trital, Lei Xu, Burhan Ates, Tzu Chen Wang, Vimalin Mani, Hu Yang Mar 2026

Ionic Liquid Pilocarpine Serves As Therapeutic Cosolvent And Permeation Enhancer For Glaucoma Medication, Ashish Trital, Lei Xu, Burhan Ates, Tzu Chen Wang, Vimalin Mani, Hu Yang

Chemical and Biochemical Engineering Faculty Research & Creative Works

The efficacy of hydrophobic ocular drugs is significantly hindered by their low bioavailability, for which poor water solubility is a major contributing factor. In this work, we synthesized pilocarpine-derived ionic liquid [Pilo-OEG] Cl (PO) and evaluated its cosolvent properties for the codelivery of the hydrophobic antiglaucoma drug brimonidine (BM) for glaucoma therapy. Pilocarpine was quaternized with 2-[2-(2-chloroethoxy) ethoxy] ethanol in a one-pot reaction to yield PO, and its structure was confirmed using 1H NMR and FT-IR spectroscopy methods and further characterized for its rheological property and thermal stability. The HET-CAM assay and cell viability study showed that PO was …


The Sortee Guidelines For Data And Code Quality Control In Ecology And Evolutionary Biology, Joel L. Pick, Bethany J. Allen, Benedicte Bachelot, Kevin R. Bairos-Novak, Jack A. Brand, Barbara Class, Tad Dallas, Pietro B. D'Amelio, Erola Fenollosa, Esteban Fernández-Juricic, Dylan G. Gomes, Matthew J. Grainger, Thomas Guillemaud, John Christian, Ruby Krasnow, Malgorzata Lagisz, Sebastian Lequime, Daniel S. Maynard, Shinichi Nakagawa, Rose E. O'Dea, Et. Al. Mar 2026

The Sortee Guidelines For Data And Code Quality Control In Ecology And Evolutionary Biology, Joel L. Pick, Bethany J. Allen, Benedicte Bachelot, Kevin R. Bairos-Novak, Jack A. Brand, Barbara Class, Tad Dallas, Pietro B. D'Amelio, Erola Fenollosa, Esteban Fernández-Juricic, Dylan G. Gomes, Matthew J. Grainger, Thomas Guillemaud, John Christian, Ruby Krasnow, Malgorzata Lagisz, Sebastian Lequime, Daniel S. Maynard, Shinichi Nakagawa, Rose E. O'Dea, Et. Al.

Faculty Publications

Open data and code are crucial to increasing transparency and reproducibility, and in building trust in scientific research. However, despite an increasing number of journals in ecology and evolutionary biology mandating for data and code to be archived alongside published articles, the amount and quality of archived data and code, and subsequent reproducibility of results, has remained worryingly low. As a result, a handful of journals have recruited dedicated data editors, whose role is to help authors increase the overall quality of archived data and code. There is, however, a general lack of consensus around what a data editor should …


Persistent Microglial Activation Following Neonatal Cmv Infection Mediates Neurodegeneration, Jessica L. Mccord, Debotri Chatterjee, John Y.S. Han, Drew Scoles, Richard J. Smeyne, Nancy J. Philp, Christopher M. Snyder Mar 2026

Persistent Microglial Activation Following Neonatal Cmv Infection Mediates Neurodegeneration, Jessica L. Mccord, Debotri Chatterjee, John Y.S. Han, Drew Scoles, Richard J. Smeyne, Nancy J. Philp, Christopher M. Snyder

Department of Microbiology and Immunology Faculty Papers

Human cytomegalovirus (HCMV) causes the most common congenital viral infection in the United States, with well-known acute and late-onset neurological pathologies. Moreover, HCMV, like multiple herpesviruses, has been associated with neuroinflammation and neurodegeneration. Using a well-established neonatal murine (M)CMV infection model, we found that early-life infection drove adult-onset neuron loss and neuropathology in the retina and brain, without evident viral reactivation. Pathology was associated with the persistence of highly activated and inflammatory damage-associated microglia. Transient depletion of these microglia before the development of pathology resulted in repopulation of the tissue by microglia with a more reparative profile, which was then …


Sentisec: Combining Keyword Heuristics And Sentiment Modeling For Ai-Powered Threat Detection, Ridho Surya Kusuma, Erum Ashraf, Selvakumar Manickam, Shankar Karuppayah Mar 2026

Sentisec: Combining Keyword Heuristics And Sentiment Modeling For Ai-Powered Threat Detection, Ridho Surya Kusuma, Erum Ashraf, Selvakumar Manickam, Shankar Karuppayah

Turkish Journal of Electrical Engineering and Computer Sciences

This work presents SENTISEC, a hybrid LLM-based threat detection framework designed to classify security logs by integrating keyword heuristics, domain-adapted sentiment scoring, and Retrieval-Augmented Generation (RAG). The system achieves an overall accuracy of 93.67%, with 91.46% macro recall, 89.07% macro F1, and 95.15% threat recall, while maintaining a low false-positive rate of 1.68%. Its methodology incorporates strict keyword and IOC matching, a domain-tuned DistilBERT sentiment module, hybrid BM25–MiniLM retrieval enhanced with BGE reranking, adaptive quantile-based threshold calibration, and SHAP-based explainability. Comparative evaluations against keyword-only, sentiment-only, classical machine-learning models, and DistilBERT-only baselines show that SENTISEC consistently improves both true-positive and true-negative …


Unraveling Metabolic Determinants Of Isoniazid Susceptibility In Mycobacterium Tuberculosis, Erin Rilu Wang Mar 2026

Unraveling Metabolic Determinants Of Isoniazid Susceptibility In Mycobacterium Tuberculosis, Erin Rilu Wang

Arts & Sciences Graduate Student Theses and Dissertations

Mycobacterium tuberculosis (Mtb) causes the disease tuberculosis (TB) and is one of the leading causes of death worldwide by an infectious agent. Furthermore, the emergence and evolution of drug resistance has significantly hindered global health efforts to combat this deadly epidemic. Thus, there is a critical need for development of new antibiotics with unique mechanisms of action and design of novel strategies for optimizing the efficacy of existing therapeutic regimens. It is estimated that 10.7% of new infected and 27.2% of previously treated TB cases are resistant to the frontline antibiotic isoniazid (INH), a central component of TB chemotherapeutic regimens. …


Cost-Effectiveness Of Blood-Based Fibrosis Screening In High-Risk Metabolic Liver Diseases With Emerging Therapies, Wanyi Chen, Stephanie T. Chang, Ramsey C. Cheung, Donald B. Chalfin, Kinpritma Sangha, Szu-Yu Zoe Kao, Artem T. Boltyenkov Mar 2026

Cost-Effectiveness Of Blood-Based Fibrosis Screening In High-Risk Metabolic Liver Diseases With Emerging Therapies, Wanyi Chen, Stephanie T. Chang, Ramsey C. Cheung, Donald B. Chalfin, Kinpritma Sangha, Szu-Yu Zoe Kao, Artem T. Boltyenkov

College of Population Health Faculty Papers

BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) remains a global public health threat. With emerging effective pharmacologic therapies, early identification of significant fibrosis in primary care is critical. We evaluated the cost-effectiveness of blood-based noninvasive tests incorporating real-world diagnostic performance in the contemporary MASLD treatment era.

METHODS: We developed a decision-analytic model for MASLD natural history and treatment to compare 6 noninvasive test strategies using Fibrosis-4 (FIB-4) and/or enhanced liver fibrosis (ELF) tests at varying cutoffs. Patients identified with significant fibrosis were referred for hepatology staging (biopsy and/or imaging-based), and eligible individuals were considered for Resmetirom ($47,400/y; mean …


Structural Insights Into Host-Pathogen Interactions Of Coronaviruses And Alphaviruses, Lucas Adams Mar 2026

Structural Insights Into Host-Pathogen Interactions Of Coronaviruses And Alphaviruses, Lucas Adams

Arts & Sciences Graduate Student Theses and Dissertations

The co-evolution of virus and host may partly be understood in terms of “cross-recognition”; that is, as a virus evolves to recognize and infiltrate a suitable cellular environment, the host reciprocally has evolved to recognize and thwart such an invasion. While this interplay is complex, audacious structural biologists may reduce it to discrete physical interactions between the virus and specific host factors, such as cognate receptors (i.e., viral recognition of host) or antibodies (i.e., host recognition of virus). These interactions underlie basic features of viral infection, including cellular tropism and antiviral immunity, as well as critical phenomena of viral evolution, …


Investigating Teachers’ Resistance To Instructional Coach Support In A Southern, Rural U.S. School District, Tukiiya Stephens Mar 2026

Investigating Teachers’ Resistance To Instructional Coach Support In A Southern, Rural U.S. School District, Tukiiya Stephens

Walden Dissertations and Doctoral Studies

Instructional coaching is a strategy designed to support systematic changes in instructional practices and improve student achievement. In the study site district, teachers were required to use instructional coaching as a mandated form of pedagogical support for enhancing teaching practices and improving student achievement. However, prior to this study, 48% of teachers did not seek support from the instructional coaches (ICs) hired to provide this job-embedded professional development. Guided by Ajzen’s theory of planned behavior, the purpose of this basic qualitative study was to investigate teachers’ perspectives regarding the lack of engagement with ICs and to identify ways to increase …


English Professor Explores Race, Culture And Value In Annual Lecture, Marvis Herring Mar 2026

English Professor Explores Race, Culture And Value In Annual Lecture, Marvis Herring

University of Mississippi News

OXFORD, Miss. – Online streaming services and digital platforms are generating record profits for the corporations that run them, but they have dramatically devalued artists' labor even as prices soar, a University of Mississippi professor contends.


Gastrointestinal Symptoms After Sport-Related Concussion In Irish Athletes, Emma Finnegan, Ed Daly, Katherine Hunzinger, Lisa Ryan Mar 2026

Gastrointestinal Symptoms After Sport-Related Concussion In Irish Athletes, Emma Finnegan, Ed Daly, Katherine Hunzinger, Lisa Ryan

Department of Exercise Science Faculty Papers

Background/Objectives: Sport-related concussion (SRC) elicits multi-systemic symptoms, including nausea, fatigue, and cognitive changes. Gastrointestinal (GI) symptoms are not well captured in current concussion assessments and may be under-recognised in clinical follow-up. GI disturbances may influence intake tolerance and day-to-day fuelling during post-SRC recovery. This study investigated the prevalence and severity of self-reported GI symptoms in Irish athletes after their most recent SRC, examined sex-based patterns, and evaluated the rationale for integrating GI symptom checks into standard concussion tools (e.g., SCAT6) and post-injury monitoring. Methods: An online survey was completed by recreational, competitive, and elite athletes who retrospectively self-reported concussion history, …


The Mediterranean Diet As A Protective Factor Against Tobacco-Induced Lung Cancer: Insights From The Italian Population, Morgan V. Roundy Mar 2026

The Mediterranean Diet As A Protective Factor Against Tobacco-Induced Lung Cancer: Insights From The Italian Population, Morgan V. Roundy

Undergraduate Honors Theses

Lung cancer is the second most commonly diagnosed cancer among men and the third among women in Italy, representing a major public health concern. This ecological, cross-sectional study examined and analyzed regional patterns of smoking prevalence, Mediterranean diet adherence, and age-adjusted lung cancer incidence across Italy, stratified by sex, using publicly available regional and macro-regional data and accounting for age structure and air quality. Smoking prevalence and lung cancer incidence were higher among males than females nationwide, although regional lung cancer patterns did not consistently mirror smoking prevalence, particularly among females. High adherence to the Mediterranean diet was low across …


Breaking Into Hiv-1'S Epigenetic Vault: Cure Strategies To Eliminate The Viral Reservoir, Joanna Jones, Chelsea Gunderson, Brian Wigdahl, Michael Nonnemacher Mar 2026

Breaking Into Hiv-1'S Epigenetic Vault: Cure Strategies To Eliminate The Viral Reservoir, Joanna Jones, Chelsea Gunderson, Brian Wigdahl, Michael Nonnemacher

Kimmel Cancer Center Faculty Papers

Human immunodeficiency virus type 1 (HIV-1) is a retrovirus that integrates into the host cell's DNA as a provirus. Transcription from the provirus is regulated in large part by cellular proteins and epigenetic factors. These may be repressive or permissive to productive infection. The host factors that regulate this balance are therefore attractive targets for HIV-1 therapeutics. Indeed, proviral chromatin is the focus of two of the current HIV-1 cure strategies. "Shock and Kill" uses latency reversal agents to open the provirus's chromatin, promoting high levels of gene expression that induce the killing of infected cells. "Block and Lock" uses …


Spatiotemporal Patterns Of Occupancy By Pygmy Rabbits (Sylvilagus Idahoensis), Kevin A. Royal, Brock R. Mcmillan, Kimberly A. Hersey, Steven L. Petersen, Randy T. Larsen Mar 2026

Spatiotemporal Patterns Of Occupancy By Pygmy Rabbits (Sylvilagus Idahoensis), Kevin A. Royal, Brock R. Mcmillan, Kimberly A. Hersey, Steven L. Petersen, Randy T. Larsen

Student Works

The pygmy rabbit (Sylvilagus idahoensis) is a species of conservation concern that has declined due to fragmentation and loss of essential habitat, primarily sagebrush-steppe. Pygmy rabbits are currently under review for listing under the U.S. Endangered Species Act (ESA) and consequently require a clearer understanding of current distribution and patterns of occurrence in big sagebrush (Artemisia tridentata) habitats. From 2024 to 2025, we surveyed for pygmy rabbits using remote cameras at several historically occupied sites in Utah, USA, to understand patterns of activity and occupancy. We also compared current estimates of occupancy to historical data collected approximately 20 years ago. …


2026-03-13 Minutes Of The Executive Committee Of The Academic Senate Senate, University Of Dayton. Academic Senate. Executive Committee Mar 2026

2026-03-13 Minutes Of The Executive Committee Of The Academic Senate Senate, University Of Dayton. Academic Senate. Executive Committee

ECAS Minutes

Approved minutes of a meeting of the Executive Committee of the Academic Senate of the University of Dayton.


Multiliteracies In The 21st-Century Classroom: Lessons From The Global South, Juan Carlos Montoya Mar 2026

Multiliteracies In The 21st-Century Classroom: Lessons From The Global South, Juan Carlos Montoya

Purdue Writing Lab/Purdue OWL Graduate Student Presentations

This presentation explores what lessons faculty engagement with critical multiliteracies, digital media, and AI leave writing centers. It highlights opportunities for writing tutors education and professional development based on faculty experience and suggestions fostering multiliteracies among students.


“You Are My Tutor, Not My Peer”: Hierarchy In Cross-Cultural Consulting In Writing Centers, Yinan Ding Mar 2026

“You Are My Tutor, Not My Peer”: Hierarchy In Cross-Cultural Consulting In Writing Centers, Yinan Ding

Purdue Writing Lab/Purdue OWL Graduate Student Presentations

Six cases of tutoring Chinese-speaking students and one case with English-speaking American student are presented to demonstrate students’ perceived hierarchy in tutoring sessions, as well as their different preferences and comfort levels with a hierarchical or peer-tutorial dynamic. Some students often addressed the tutor with the formal “you” in Mandarin Chinese, preferred to call tutors “teachers,” and expressed admiration for tutors' educational background, while English-speaking students occasionally signal hierarchical expectations, suggesting this phenomenon may transcend a single cultural group. To build writing centers as supportive, interconnected ecosystems of learning, it is important to conduct further research on students’ perceptions and …


Minding The Gap: Exploring The Hidden Curriculum Of Your Writing Center, Erin Del Busto Mar 2026

Minding The Gap: Exploring The Hidden Curriculum Of Your Writing Center, Erin Del Busto

Purdue Writing Lab/Purdue OWL Graduate Student Presentations

In this interactive workshop, tutors and writing center directors will be invited to reimagine how they scaffold individual sessions. By engaging in hands-on activities, group discussions, and take-home materials, attendees will walk away from this workshop with greater clarity about how to utilize the “hidden curriculum” present in all sessions: how it shapes the tutor’s understanding of their role, the writer, and what it means for a session to be successful.


Heterocyclic‐Fused Squaramides: Anionophores With Antimicrobial Activity, Luke Edward Brennan, Chris Samuel Hawes, Kevin Kavanagh, Robert Brian Peter Elmes Mar 2026

Heterocyclic‐Fused Squaramides: Anionophores With Antimicrobial Activity, Luke Edward Brennan, Chris Samuel Hawes, Kevin Kavanagh, Robert Brian Peter Elmes

Research Outputs: 2025-Present

Antimicrobial resistance is regarded as one of the foremost public health risks of the 21st century, highlighting the need for new antimicrobial agents and chemical tools to interrogate their biological activity. Artificial transmembrane anion transporters have emerged as promising supramolecular scaffolds in this context, having demonstrated membrane activity in mammalian systems and showing growing potential in antimicrobial research. Here, we report a series of heterocycle‐fused squaramide anionophores capable of binding and transporting chloride. Several members of this series display measurable antimicrobial activity, alongside evidence of intracellular chloride modulation in bacterial cells. Taken together, these findings indicate that membrane localisation and …