Digital Commons Network^™

Antidepressant-Like Effects Of Extinction Learning As An Animal Model Of Behavioral Therapy, Jing Liu, Sarah E Bulin, David A Morilak

Faculty, Staff and Student Publications

Exposure-based behavioral therapy, the most effective treatment for posttraumatic stress disorder (PTSD), also reduces depressive symptoms. However, neurobiological mechanisms underlying the beneficial effects of exposure-based behavioral therapy on depression remain unknown. Our lab has established fear extinction as a rat model of exposure therapy to investigate the mechanisms underlying its therapeutic behavioral effects in chronically stressed rats. In this study, we demonstrated that extinction learning reduced immobility in the forced-swim test and reversed chronic stress-induced reduction in sucrose preference. Chemogenetic inactivation of pyramidal neurons in the ventral medial prefrontal cortex (vmPFC) prevented these antidepressant-like effects of extinction. Extinction learning enhanced …

Creating Space For New Ideas And Advancing Gender Equity In Physical Activity And Health Research: Reflections On The Nature Portfolio Physical Activity Series, Andrea Ramírez Varela, Deborah Salvo, Pedro C Hallal, Erica Hinckson

Faculty, Staff and Student Publications

No abstract provided.

Computational Modeling Meets 3d Bioprinting: Emerging Synergies In Cardiovascular Disease Modeling, Tanmay Mukherjee, Mehdi Salar Amoli, Sarah Rezapourdamanab, Lama Rita El Shammas, Martin L Tomov, Emilio A Mendiola, Vahid Serpooshan, Reza Avazmohammadi

Faculty, Staff and Student Publications

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide, underscoring the need for improved strategies in diagnosis, treatment, and disease modeling. Traditional in vitro models often fall short in replicating human CV physiology, prompting efforts to advance cardiac tissue engineering and computational modeling. Among these, three-dimensional (3D) bioprinting has emerged as a transformative tool, enabling the creation of biomimetic CV constructs that more faithfully replicate native tissue structure and function. However, challenges persist in achieving appropriate mechanical properties and long-term performance of engineered CV constructs. Computational modeling offers powerful solutions to assist with these challenges, providing predictive insights into …

Are Drains After Trauma Splenectomy Associated With Organ Space Surgical Site Infections?, Stephanie Martinez Ugarte, Mokunfayo O Fajemisin, Seokhun Kim, William D Rieger, Renee W Green, Gabrielle E Hatton, Lillian S Kao

Faculty, Staff and Student Publications

Introduction: Left upper quadrant (LUQ) drain use after trauma splenectomy varies, with minimal existing data to guide practice. We aimed to investigate the association of LUQ drains with organ space surgical site infection (OS-SSI) after splenectomy. We hypothesized that LUQ drains after trauma splenectomy are associated with increased odds of OS-SSI.

Patients and methods: A retrospective study of adult blunt trauma patients who underwent splenectomy from 7/2018 to 6/2024 was performed. We excluded patients who survived < 5 days after operation, and those with an intraoperatively identified pancreatic injury. Demographics, surgical details, and drain information were abstracted from the medical record. Inverse probability of treatment weighting (IPTW) was used to balance variables between patients who did and did not receive an LUQ drain after splenectomy. Multivariable logistic regression with IPTW was performed to estimate the association of LUQ drains with OS-SSI.

Results: Of 179 patients, 68% (n = 121) were male, the median age was 38 years (interquartile range 28, 55), and 27% (n = …

An Assessment Of Green Plasma: The In Vitro Hemostatic Superiority Of A Currently Discarded Blood Product, Samantha C Redden, David J Sun, Yao-Wei W Wang, Elizabeth Hartwell, Jessica C Cardenas, Scott D Olson, Bryan A Cotton

Faculty, Staff and Student Publications

Introduction: Recent studies have linked trauma patient outcomes to the plasma donor's sex, with premenopausal females associated with improved survival and lower organ failure. Currently, green-colored plasma (due to oral contraceptive use) is removed from the donor pool. We set out to evaluate the hemostatic potential of green plasma.

Study design & methods: We obtained 90 units of plasma from our regional blood center: 30 units of visible green plasma and 60 units of standard-color plasma divided between male and female donors. We collected clinical data such as age, sex, ethnicity, and number of pregnancies. We then assessed the hemostatic …

Ecological Insights And Management Implications Of The Global Migratory Connectivity Of Green Turtles, Jaime Restrepo, Dina Nisthar, Harris Wei-Khang Heng, Lily K. Bentley, Corrie Curtice, Sarah Deland, Ei Fujioka, Patrick N. Halpin, Sarah K. Poulin, Roldán A. Valverde

School of Earth, Environmental, & Marine Sciences Faculty Publications

Aim

Green turtles are a widely distributed and highly migratory species; despite extensive data on their movement, there is no species-specific global synthesis on the subject. Based on three decades of published literature and building on previous global analyses, we developed a global network model of migratory connectivity for green turtles to better understand their spatial biology.

Location

Global.

Time Period

1990–2022.

Major Taxa Studied

Green Sea Turtle (Chelonia mydas).

Methods

We conducted a structured literature review extracting georeferenced information on the movement of green turtles from 1990 to 2022, aggregating this information into a single connectivity model, …

A Systematic Review And Meta-Analysis On The Levels Of Supportive Care Needs In Adults With Cancer, Caroline B. Silveira, Rech, Maria Petropoulou, Pietro S. Rössler, Francine F. De Souza, Helena B. Böhmer, Amanda L. Giacomet, Richard Alejandro B. De Barros, Lucélia De C. De Barros, Vagner R.Z.B. Pereira, Nanci Da S.T. Junqueira, Pedro Lopez

Research outputs 2022 to 2026

Objective: To estimate the levels of supportive care needs among adults with cancer using the Supportive Care Needs Survey–Short Form 34 (SCNS-SF34) and to examine demographic, clinical, and treatment-related determinants. Methods: A systematic review and meta-analysis was conducted (CRD42024604977). Studies reporting SCNS-SF34 scores in adults with cancer were included. Searches were performed across six different databases (November 2024; updated August 2025). Random-effects meta-analyses were undertaken to estimate the pooled mean scores across the five SCNS-SF34 domains and total score. Subgroup and meta-regression analyses explored potential determinants. Results: Ninety-five studies (n = 32,493) were analysed. The unmet needs observed tended to …

Expanding Links Between Work Values And Occupations: Development Of The Occupational Values Inventory (Ovi), Nicholas F. Heimpel, Kevin Hoff, Zihan Liu, Federick L. Oswald, James Rounds

Research Collection Lee Kong Chian School Of Business

This research developed the Occupational Values Inventory (OVI), a 30-item measure that expands the content coverage of work values by linking into a broad range of O*NET occupational descriptors, including Work Activities and Work Contexts, along with salary data from the Bureau of Labor Statistics. The OVI assesses 11 work values—Interpersonal, Outdoor, Physical, Leadership, Salary, Prestige, Variety, Interest, Work Hours, Knowledge Utilization, and Autonomy—providing an updated and refined coverage of work values relevant to people and occupations in the modern labor market. Study 1 (N = 768) developed and refined the OVI’s scales using conceptual and psychometric criteria, also reporting …

International Business And Sustainability: Towards An Interdisciplinary Research Agenda, Jonathan Doh, Ans Kolk, Heli Wang

Research Collection Lee Kong Chian School Of Business

The relationship between international business (IB) and sustainability is a complex and multifaceted one. Multinational enterprises (MNEs) both affect and are affected by the social, economic, and ecological (green environment) context in which they are embedded.1 As such, the study of how IB activity influences sustainability and the way that sustainability, in turn, impacts IB, involves incorporating a wide range of drivers, actors, processes, and outcomes. At the same time, sustainability challenges, such as climate change, biodiversity loss, pollution, resource scarcity, economic and social inequality and others, are increasingly systemic, multilevel, and intertwined with geo economic, biophysical and governance dynamics …

Research: What Message Are Your Headphones Sending Your Coworkers?, Oguz Gencay, Michael Schaerer, Trevor A. Foulk

Research Collection Lee Kong Chian School Of Business

Walk into almost any modern office, and you will see it: earbuds in, playlists on, and heads down. For many employees, music is an essential tool for focusing, mood regulation, and stamina. For most managers, it is a non-issue as long as performance stays strong. If it helps people concentrate, let them listen to music. At worst, it is a harmless preference, such as drinking coffee or using a standing desk.

Kroc Ipj Border Fellows Report 2024 — English, Rebeca Cázares Adame

Kroc IPJ Research and Resources

The Kroc Border Fellows Program brings together change agents from academia, civil society, the public sector, and the private sector to build a more inclusive and peaceful Mexico-U.S. border region through action-oriented research and meaningful community partnerships.

The non-residential fellowship spans 10 months and provides financial and technical support for Fellow-designed and -implemented projects. This model reflects a core belief that those closest to border communities' challenges are best positioned to develop effective solutions — and that lasting change must be built on existing community assets and strengths.

Throughout the fellowship, cohort members meet regularly to foster collaboration, mutual learning, …

Juanita Stout Ray: Life On The Frontier, A 20th Century Latter-Day Saint Woman's Life, Karen Glenn, John Murphy, Elspeth Rayback-Maxwell, Hallie Davidson

Faculty Publications

This exhibit explores the life of Juanita Stout Ray (1891-1954), a Latter-day Saint woman whose journals, letters, photographs, and family records provide a rare and intimate view of women's experiences in the early twentieth-century American West. Born in southern Utah and raised in a polygamous family, Ray spent part of her childhood in the Mormon colonies of northern Mexico before her family fled during the Mexican Revolution. Her life was shaped by many of the defining events of her era, including revolution, pandemic, economic hardship, world war, migration, and profound personal loss.

The exhibit traces Ray's experiences as a teacher, …

Advancing Statistical Literacy In Eye Care: A Series For Enhanced Clinical Decision-Making: Part 3: Design And Analysis Of Clinical Research In Eye And Vision Studies, Daniela Oehring

School of Health Professions

Purpose. To provide comprehensive guidance on designing and analysing clinical research studies in ophthalmology and optometry, encompassing observational studies, non-randomised controlled trials, randomised controlled trials, and advanced trial methodologies including platform trials, adaptive designs, and decentralised trials. This article addresses the unique methodological challenges in eye and vision research while integrating contemporary frameworks such as the estimands approach for defining treatment effects and the ethical imperative of systematic reviews before initiating new trials.Material and Methods. A comprehensive literature review was conducted using PubMed, Scopus, Web of Science, and Cochrane databases, focusing on study designs applicable to eye care research with …

Rationalizable Incentives: Interim Rationalizable Implementation Of Correspondences, Takashi Kunimoto, Rene Saran, Roberto Serrano

Research Collection School Of Economics

Are there ways to enforce incentives free of equilibrium considerations? When the normative goals for a set of agents can be summarized in a set-valued rule and agents take actions that are rationalizable, a new theory of incentives emerges in which standard Bayesian incentive compatibility (BIC) is relaxed significantly. The paper studies the interim rationalizable implementation of social choice sets with a Cartesian product structure, a leading example thereof being ex-post efficiency. Setwise incentive compatibility (setwise IC), much weaker than BIC, is shown to be necessary for implementation. Setwise IC enforces incentives flexibly within the entire correspondence, instead of the …

Using Satellite-Observed Geospatial Inundation Data To Identify The Impacts Of Floods On Firm-Level Performance: The Case Of China During 2000–2009, Pao-Li Chang, Fan Zheng

Research Collection School Of Economics

This paper compiles high-resolution geospatial inundation areas of China for the period 2000–2009 based on satellite imagery repositories filtered by the Global Flood Database (GFD). In parallel, we geocode a comprehensive firm-level dataset of China and combine these two sets of geospatial data to identify the set of inundated firms in each year of flood events, as well as the distances of all non-inundated firms from the inundated areas. Given the high-resolution inundation data, we adopt a generalized dynamic-panel specification to estimate dynamic and spatial spillover effects of floods on firm-level production activities (including outputs, capital and labor inputs, and …

Improving Estimation Efficiency Via Regression-Adjustment In Covariate-Adaptive Randomizations With Imperfect Compliance, Liang Jiang, Oliver B. Linton, Haihan Tang, Yichong Zhang

Research Collection School Of Economics

We study how to improve efficiency via regression adjustments with additional covariates under covariate-adaptive randomizations (CARs) when subject compliance is imperfect. We first establish the semiparametric efficiency bound for the local average treatment effect (LATE) under CARs. Second, we develop a general regression-adjusted LATE estimator which allows for parametric, nonparametric, and regularized adjustments. Even when the adjustments are misspecified, our proposed estimator is still consistent and asymptotically normal, and their inference method still achieves the exact asymptotic size under the null. When the adjustments are correctly specified, our estimator achieves the semiparametric efficiency bound. Third, we derive the optimal linear …

Investigating Speech-Language Pathologists’ Perceptions On Bilingual/Multilingual Aac Intervention And Quality Of Care, Lillian D. Griffith

Communication Disorders and Occupational Therapy Undergraduate Honors Theses

This study examined U.S.-based speech-language pathologists' (SLPs) perceptions of bilingual/multilingual AAC service provision and the barriers SLPs encounter to determine if SLP beliefs align with practices. An anonymous survey was distributed to 307 ASHA-certified SLPs, resulting in 21 completed responses. The survey consisted of questions that gathered information on participant demographics, caseload, perceptions/beliefs, and practices, with optional open-ended questions for additional context. SLPs in the participant sample strongly believed that AAC intervention should occur in all the languages spoken by the client. Despite this belief, they struggled to implement it due to barriers. Key barriers identified included SLP language limitations, …

Aspirin And Preterm Birth Among Pregnant People With Increased Heat Exposure: Secondary Analysis Of A Randomized Clinical Trial, Gabriella Meltzer, Luke Duttweiler, Sarah Saleem, Kartik Shankar, Manolo Mazariegos, Antoinette Tshefu, Jackie Patterson, Elwyn Chomba, Waldemar Carlo, Shivaprasad Goudar, Richard Derman, Archana Patel, Patricia Hibberd, Edward Liechty, Fabian Essamai, Edwin Asturias, Denise Babineau, Janet Moore, Cascade Tuholske, Andrew Zimmer, Brent Coull, Elizabeth Mcclure, Robert Goldenberg, Nancy Krebs, Matthew Hoffman, Blair Wylie

Global Health Articles

IMPORTANCE: Scalable interventions are urgently needed to mitigate the adverse effects of heat on pregnancy and newborn health.

OBJECTIVE: To evaluate whether low-dose aspirin modifies the association between heat exposure and preterm birth.

DESIGN, SETTING, AND PARTICIPANTS: This secondary analysis of the Global Network for Women's and Children's Health Research Aspirin Supplementation for Pregnancy Indicated Risk Reduction in Nulliparas (ASPIRIN) randomized, double-blinded, placebo-controlled clinical trial was conducted from March 2016 to June 2018. Statistical analyses were performed from June 2024 to June 2025. The study settings included the Democratic Republic of Congo, Zambia, Kenya, Guatemala, Pakistan, and Belagavi and Nagpur, …

2-D Materials: The Synthesis Of Solid-State Fuel From Metastable Diboride, Alma Kolakji

Chemistry

2-D materials are widely recognized for their anisotropic mechanical and electrical properties, surpassing their bulk counterparts. These superior characteristics of 2-D materials arise from their high surface-to-volume ratio and strong in-plane bonds. Current routes to exfoliate bulk material into 2-D nanosheets rely on weak interlayer Van der Waals forces and traditional top-down techniques. These methods are dominated by physical “force,” such as liquid-phase and mechanical exfoliation. The downside is that they apply only to weakly bonded VdW materials, limiting the variety of possible 2-D materials. To expand the variety, researchers have studied the synthesis of borophene (boron sheets). Borophene is …

Sectoral Differences In The Role Of Aggregate Corporate Earnings In Predicting Gdp, Aleeza Reich

Business/Business Administration

This paper provides empirical evidence on aggregate corporate earnings growth as a predictor of gross domestic product (GDP) growth at the sectoral level in the US. We explore how sectoral earnings predict sectoral GDP with and without controls to examine more accurate methods of GDP forecasting. Utilizing panel data for fifteen sectors from 2005 to 2024, we examine this predictive relation on a quarterly basis. Our results show that sectoral earnings can predict sector GDP in seven of the fifteen sectors either contemporaneously or with a lag. These results can aid policymakers as well as investors in making more accurate, …

Leading Ai Adoption In Organizations: Introducing A Behavioral Human-Centered Approach, Shane Schweitzer, Devesh Narayan, Jack Mcguire, David De Cremer

Research Collection Lee Kong Chian School Of Business

Initiatives to implement AI technologies in organizations fail at an alarming rate. We argue that leading the adoption of AI is not a simple engineering exercise but rather represents a behavioral exercise where change management principles—the process by which organizations plan, implement, and embed changes in practices—are employed. However, many AI initiatives in business focus predominantly on the AI systems themselves, assuming humans will fall in line. To solve this, we integrate ideas from change management with scholarship on human-centered artificial intelligence to offer a behavioral approach that accounts for the impact of AI adoption on humans at all stages …

The Downside Of Generosity: How Rare Giving Fosters Stronger Social Connection, Minkwang Jang, Shereen J Chaudhry, Ayelet Fishbach

Research Collection Lee Kong Chian School Of Business

Giving serves not only to benefit others and society but also to foster social connections between givers and recipients. However, more giving is not necessarily merrier. This research finds that social connection depends not only on the act of giving but also on how many others receive the gesture from the same giver. Rare givers—those who give to fewer recipients—are perceived as more socially connected to each recipient than broad givers—those who give to many (the rare giving effect). This effect emerges across diverse contexts, including interpersonal gift exchanges in both new and existing relationships and corporate donations. As a …

Public Pool Usage As Adaptation Against Urban Heat, Stefan Borsky, Eric Fesselmeyer

Research Collection College of Integrative Studies

This paper examines the relationship between urban heat and outdoor public pool usage. Using attendance data from all 53 outdoor public pools in New York City, we analyze nonlinear effects of heat on pool usage across socioeconomic contexts. Pool attendance rises sharply with heat, especially in low-income neighborhoods where alternative coping options are likely limited. We also find that public pools reduce heat-related emergency medical service calls. Our findings highlight the need for equitable investment in blue infrastructure to enhance urban climate resilience and demonstrate how this type of adaptive infrastructure can play a critical role in managing urban heat.

A Qualitative Study Of Journalism Course Syllabi In Relation To The First Amendment, Elizabeth L. Bunnell

Journalism Undergraduate Honors Theses

The goal of this research is to gain more insight into collegiate journalism course syllabi and the First Amendment. The First Amendment is a foundational aspect for a career in journalism, and one way to learn how college journalism students are interacting with the First Amendment is to conduct a qualitative analysis of the syllabi. A syllabus is the contract between professor and student for the course; therefore, it should contain the most important information relating to the course. 47 syllabi were collected from the School of Journalism and Strategic Media from the Spring 2025 semester. After reading through each …

Evaluation Of The Weed Control Efficacy And Potential Economic Returns Of An Autonomous Weeder In Vegetable Production Systems, Claire Plassmeyer

Graduate Theses and Dissertations

Vegetable production requires intensive weed management. Conventional producers rely on herbicide applications to manage weeds effectively at low costs; however, growers are under pressure to minimize chemical use due to environmental concerns and increased incidences of herbicide resistance. Non-conventional systems, including organic and sustainably focused small-scale production, rely primarily on cultural practices and physical weed control methods, which are labor-intensive and costly due to limited labor availability and rising wages. These concerns have prompted the development of autonomous weeding devices, such as unmanned ground vehicles (UGVs) equipped with navigation sensors and implements to provide repeated, high-precision weed control. Compact devices …

Attachment And Betrayal: Post-Infidelity Attachment Issues With A Focus On Gender, Taylor Forsythe

Electronic Theses and Dissertations

Infidelity represents a significant relational trauma that may disturb attachment processes such as trust, emotional intimacy, and closeness. There is a gap in the literature on how different infidelity exposures may relate to these attachment responses; more so, there is a dearth of information on the gender differences for attachment issues following any kind of infidelity. The purpose of this study aimed to examine differences in avoidant and anxious attachment across infidelity groups (no infidelity, non-sexual infidelity, sexual infidelity), and a further comparison of gender differences in those groups. Participants (N = 151) completed online surveys in a larger study …

Reading The Wisdom Of Psalm 37 Through The Lens Of Metaphor And Lament, Hannah N. Johanson

Electronic Theses and Dissertations

This thesis proposes that reading Ps 37 through the lens of both metaphor and lament can reshape the way the reader understands the reality of evil, fostering hope and agency. While Ps 37 is often classified as a wisdom psalm, this thesis diverges from the interpretation that this psalm is a list of proverbs. Instead, this thesis attempts to show that Ps 37 forms a metaphorical landscape where evil withers, vanishes, and is cut off while goodness thrives and is secured forever. This thesis also places this psalm in dialogue with two poems that engage Ps 37 from a post-Shoah …

Tribological Evaluation Of A Graphite Coating Using A Custom Miniature Conveyor, Shae Threlfall

Mechanical Engineering Undergraduate Honors Theses

Reducing friction in conveyor systems has significant economic and environmental implications, as a substantial portion of energy losses originates at the belt-bed interface. This thesis outlines the design, construction, and validation of a miniature conveyor tribological test system. Unlike conventional tribometers, which impose concentrated point contacts, the miniature conveyor replicates the distributed load consistent with industrial conveyor systems. It can measure real-time mechanical responses of steel samples coated in a low friction coating.

The mini conveyor was validated by evaluating three materials: uncoated mild steel, PDA/graphite coated steel, and Polytetrafluoroethylene (PTFE). Electrical power, temperature, sound, and acceleration were recorded. Electrical …

The Impact Of Traditional Machismo On Mental Health Outcomes: Depression And Suicide Risk Among Latino Immigrant And Non-Immigrant Men, Yesenia A, Romero

Electronic Theses and Dissertations

Traditional masculine norms have long been recognized as influential factors in men’s psychological well-being. Within Latino cultures, the construct of machismo represents a culturally specific form of masculinity characterized by ideals of masculinity and characterized by ideals of strength, dominance, and emotional restraint. While these norms may promote resilience and family responsibilities, rigid adherence to traditional machismo has also been associated with emotional suppression, reduced help-seeking behaviors, and increased psychological distress. The present study conducted a meta-analysis to examine the relationship between traditional machismo and mental health outcomes among Latino men, with particular attention to depressive symptoms as well as …

Cultivating Diversity: Investigating Hispanic College Students’ Attitudes Toward Teaching Amid The U.S. Teacher Shortage Crisis, Daniela Andrea Hernandez

Electronic Theses and Dissertations

The underrepresentation of Hispanic teachers in U.S. public education remains a significant concern as Hispanic students comprise a growing proportion of the K–12 population. Despite this demographic shift, the educator’s workforce has not reflected the cultural and linguistic backgrounds of the students it serves. The purpose of this qualitative descriptive study was to explore first- and second-year Hispanic college students’ perceptions of teaching as a profession and to examine how their educational and personal experiences influenced their career interests. The study was informed by social cognitive career theory and culturally relevant teaching theory to better understand how self-efficacy, outcome expectations, …