Digital Commons Network^™

A Cytomics-On-A-Chip Platform And Diagnostic Model Stratifies Risk For Oral Lichenoid Conditions, Michael P Mcrae, Kritika Srinivasan Rajsri, A Ross Kerr, Nadarajah Vigneswaran, Spencer W Redding, Malvin Janal, Stella K Kang, Leena Palomo, Nicolaos J Christodoulides, Meena Singh, Jeffery Johnston, John T Mcdevitt

Faculty, Staff and Student Publications

Objective: A small fraction of oral lichenoid conditions (OLC) have potential for malignant transformation. Distinguishing OLCs from other oral potentially malignant disorders (OPMDs) can help prevent unnecessary concern or testing, but accurate identification by nonexpert clinicians is challenging due to overlapping clinical features. In this study, the authors developed a 'cytomics-on-a-chip' tool and integrated predictive model for aiding the identification of OLCs.

Study design: All study subjects underwent both scalpel biopsy for histopathology and brush cytology. A predictive model and OLC Index comprising clinical, demographic, and cytologic features was generated to discriminate between subjects with lichenoid (OLC+) (N = 94) …

Sex Differences In Spontaneous Respiratory Recovery In Chronic Hemisection, Taylor C. Holmes, Nicole M. Popp, Carley F. Hintz, Isabell Dobrzycki, Carolyn J. Schmitz, Kaylyn A. Schwichtenberg, Elisa J. Gonzalez-Rothi, Christopher W. Sundberg, Kristi A. Streeter

Physical Therapy Faculty Research and Publications

Respiratory deficits after C2 hemisection (C2Hx) have been well documented through single-sex investigations. Although ovarian sex hormones enable enhanced respiratory recovery observed in females 2 wk post-C2Hx, it remains unknown if sex impacts spontaneous respiratory recovery at chronic time points. We conducted a longitudinal study to provide a comprehensive sex-based characterization of respiratory neuromuscular recovery for 8 wk after C2Hx. We recorded ventilation and chronic diaphragm electromyography (EMG) output in awake, behaving animals, phrenic motor output in anesthetized animals, and performed diaphragm muscle histology in chronically injured male and female rodents. Our results show that females expressed a greater recovery …

Assessing The Knowledge And Awareness Of Us Oncologists Regarding The Specialty Of Oral Medicine, Alessandro Villa

All Publications

Objectives: This cross-sectional study aimed to assess the awareness among United States (US) oncologists about oral medicine (OM) as a specialty of dentistry, and their collaboration with OM providers.

Methods: An online survey was conducted, inviting 1350 US oncologists, with data collected on demographics, practice background, comfort level with diagnosing and treating oral conditions, referral practices for oral conditions, and more.

Results: Of the invited 1350 oncologists, 192 responded (14% response rate). Among respondents, 46% were familiar with the OM specialty. Of these, 73% had previously sought consultation from OM specialists. The primary reasons for referral included dental clearance before …

Asynchronous Movement Patterns Between Breeding And Stopover Locations In A Long-Distance Migratory Songbird, Theodore J. Zenzal Jr., Andrea Contina, Hannah B. Vander Zanden, Leanne K. Kuwahara, Daniel C. Allen, Kristen M. Covino

School of Integrative Biological & Chemical Sciences Faculty Publications

The species-specific migratory patterns and strategies of many songbirds remain unknown or understudied, as research in animal ecology is biased toward the breeding period, with the fewest studies on the migratory period across taxa. Identifying large-scale spatiotemporal migratory patterns is challenging, as individuals within a species may vary in their migratory behavior and strategies. The Yellow Warbler (Setophaga petechia) is a Nearctic-Neotropical migrant that is relatively well studied during the breeding season, but its species-wide migratory patterns remain understudied. Our aim in studying Yellow Warbler movement ecology was to characterize temporal migration patterns during fall migration. We sought …

Parental View On Hpv Vaccination, Rebecca Elaine Rhodes

Electronic Theses and Dissertations

The human papillomavirus (HPV) is a sexually transmitted infection widely seen in the United States. Millions of Americans are affected by it each year, especially those in their late teens and early 20s. Although most infections will resolve on their own, 1 in 10 will lead to health problems such as cancer. The HPV vaccine can prevent over 90% of associated precancers and cancers. However, uptake of the HPV vaccine and its completion among adolescents are significantly lower than other recommended adolescent immunizations, falling short of the Healthy People 2030 goal of 80% coverage. Understanding parental attitudes, beliefs, and perceptions …

Improvement Of Triboelectric Nanogenerator By As-Prepared Lithium Niobate For Energy Harvesting And Sensing Applications, Jahid Inam Chowdhury

Theses and Dissertations

One readily available green energy source that is used to address the small-scale energy requirement is mechanical energy. To harvest mechanical energy, supply energy for upcoming electronic devices, and enable flexible health monitoring, triboelectric nanogenerators composed of perovskite and lightweight polymers have garnered significant interest. A material named lithium niobate (LiNbO3) was produced in two different phases and used to make a flexible triboelectric nanogenerator (TENG). Furthermore, lightweight polydimethylsiloxane (PDMS), Polyvinyl Alcohol (PVA), and LiNbO3 nanoparticles were used to produce a small triboelectric nanogenerator that successfully converts mechanical energy into electricity. LiNbO3 nanoparticles were first created and loaded into polydimethylsiloxane …

Mitigating The Greenhouse Gas Footprint Of Hydropower Via Floating Solar Photovoltaic Integration: A Modeling And Predictive Analysis Study, Areefin Ul Hassan Chowdhury

Theses and Dissertations

Hydropower is typically considered a low-carbon energy source; however, some hydropower facilities exhibit high greenhouse gas (GHG) intensities due to emissions from their reservoirs. This study evaluates the potential for offsetting GHG intensities by integrating floating solar photovoltaics (FPV) with reservoir-based hydropower. Our assessment indicates that technically feasible FPV–hydropower integrations could enable over 50% of the world’s GHG-intensive hydropower plants to achieve low-GHG energy benchmarks, with significant implications for both hydropower management and climate change mitigation. To support this analysis, we conducted clustering analysis to investigate the potential for reservoir segmentation. Following this, we applied various regression methods to predict …

Calibration And Use Of The Transparency Tube As An Estimate Of Turbidity: An Analysis Of Factors Controlling Light Attenuation In Estuarine Waters, Makenna Leigh Thompson

Theses and Dissertations

The transparency tube is low-cost, portable, and easy to use to measure the transparency or clarity of the water. Filling the tube with water creates a small-scale water column where water will be slowly drained out of the bottom until the Secchi disk at the bottom of the tube is visible from the top opening, and the depth of the remaining water in the tube is recorded in centimeters. Unlike traditional Secchi disk measurements, the advantage of this instrument is that sampling depth in highly turbid waters is possible with a centimeter scale resolution. Transparency tube measurement, through careful calibrations, …

Associations Between Neurological Correlates Of Reading And Learning Disability Profiles Among Children, Jessica Luedke

Theses and Dissertations

Early reading skills are vital for child development. Children with specific reading learning disabilities (SLD-R) display persistent difficulties acquiring reading skills. They are at an increased risk for adverse life outcomes, including mental health concerns, low educational attainment, and low academic motivation. Progress in neurobiological research provides opportunities to enhance the assessment and identification of learning disabilities by revealing distinct neurological patterns of learning. However, the integration of this progress with school psychology research is rare. The purpose of the current study was to evaluate brain network connectivity as a biomarker of reading using resting-state quantitative electroencephalography (QEEG) coherence. Fronto-central …

Antioxidant And Anti-Inflammatory Potential Of Engineered Ceria Nanoparticles In The Management Of Alzheimer's Disease, Shanshan Shi

Theses and Dissertations

Alzheimer's disease (AD) is a devastating neurodegenerative disorder that affects millions worldwide. Unfortunately, there are currently no effective therapies available to prevent or cure the disease. While current therapies aim to change AD progression, there is a growing need for novel therapeutic strategies that can effectively penetrate the blood-brain barrier (BBB) to target the underlying pathology of the disease. The BBB is a highly selective semipermeable barrier that separates circulating blood from the brain. It plays a crucial role in amyloid-β (Aβ) homeostasis and clearance dynamics, as Aβ accumulation is a key factor in the pathogenesis of AD. Aβ aggregation …

Preregistration And Registration As A New Method For Transparency Of External Validation In Artificial Intelligence And Machine Learning Applications To Address Overfitting, Underspecification, And Shortcut Learning, Marilyn Elaine Gartley

Theses and Dissertations

Statistics has been defined as the study of how information should be employed to reflect on and give guidance for action in a practical situation involving uncertainty. The essence of uncertainty is that there is more than one possible outcome, and the actual outcome is unknown in advance; it is indeterminate. The goal of statistical methods is inference: namely, statistical inference—reaching conclusions about populations or deriving scientific insights from data which are collected from a representative sample of that population through providing a mathematical understanding of inference, quantifying the degree of support that data offer for assertions of knowledge, as …

Initial Evaluation Of A Peer Supervision Program For Health Service Psychology Doctoral Students, William Bradley

Theses and Dissertations

Clinical supervision has long been utilized as the primary method of clinical training and evaluation for health service psychology doctoral students. Despite the central role that supervision has played and continues to play in the training of psychologists, little scholarly attention has been given to identifying effective methods for fostering competency in providing supervision. The lack of research in this area is concerning, given the accumulating evidence that negative supervision experiences, such as ineffective or inadequate supervision, are reported by a substantial proportion of trainees (21-92% across studies). Moreover, these experiences are associated with important proximal and distal training outcomes, …

Nonverbal Iq Test Performance In Preschool-Age Children With Varying Language, Sandra Danelle Irvin

Theses and Dissertations

Purpose – This study aims to investigate the impact of two types of factors on IQ test performance in children with variation in language ability. The two types of factors studied here are: a) test characteristics (i.e., complexity of test directions) and test-taker characteristics (i.e., language ability). Method – Four participants, ages 4-7, completed norm referenced assessments for language and intelligence. Results – Descriptive results suggest no discernable trends between performance on language assessments and nonverbal IQ measures. The results demonstrated a discernable negative trend between performance on nonverbal IQ measures and linguistic complexity of instructions. Implications – While the …

Hardening Interpretable Deep Learning Systems: Investigating Adversarial Threats And Defenses, Eldor Abdukhamidov, Mohammed Abuhamad, Simon S. Woo, Eric Chan-Tin, Tamer Abuhmed

Computer Science: Faculty Publications and Other Works

Deep learning methods have gained increasing attention in various applications due to their outstanding performance. For exploring how this high performance relates to the proper use of data artifacts and the accurate problem formulation of a given task, interpretation models have become a crucial component in developing deep learning-based systems. Interpretation models enable the understanding of the inner workings of deep learning models and offer a sense of security in detecting the misuse of artifacts in the input data. Similar to prediction models, interpretation models are also susceptible to adversarial inputs. This work introduces two attacks, AdvEdge and AdvEdge + …

A Study Of Electron- And Photon-Induced Dissociative Electron Attachment To Molecules And Within Anion-Molecule Clusters, Mahmudul Hasan

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Dissociative electron attachment (DEA) is a resonant process in which a molecule captures a low-energy electron, forming a transient negative ion (TNI). Subsequently, this unstable TNI fragments into a stable anion and one or more neutral fragments. DEA is crucial in various phenomena, ranging from atmospheric and radiation chemistry to processes occurring in plasmas, and is particularly significant in the context of radiation-induced damage to biological molecules. This study uses different experimental methods to better understand the fragmentation in molecular anions forming through dissociative photoexcitation and electron attachment. We have developed an experimental apparatus for dissociative photoexcitation studies. This apparatus …

Perceived Context Typicality And Beliefs In The Generalizability Of Management Research Findings, Przemyslaw Hensel, Adam Tatarynowicz

Research Collection Lee Kong Chian School Of Business

Despite growing calls for a greater internationalization of management research, the discipline still struggles with the challenge of integrating diverse national contexts. While recent decades have seen a change toward a more equitable treatment of all national contexts, the belief that research conducted outside the United States is less generalizable remains strong. In this research note, we explore the general perceptions of what is considered a “typical” study context by associating them with authors' variable tendencies to report threats to external validity. Using a sample of 400 papers from seven top-tier management journals, we find that research based on non-US …

Cds Channels Of Influence On Discretionary Accruals, Hao Cheng, Kian Guan Lim

Research Collection Lee Kong Chian School Of Business

Existing studies indicated that firm debt holders can use the credit default swap (CDS) market to hedge their credit risk, and thus they would reduce their monitoring of the firms, leading to largely distressed firms shirking and increasing positive abnormal earnings accruals. Besides providing insurance, however, the CDS spreads also perform price discovery of credit risk information sought by trade creditors and potential lenders who are not protected. High absolute abnormal discretionary accruals or bad earnings quality, especially negative abnormal accruals, would lead adverse CDS price signals that are very costly to the firm. This compels the firm under nondistressed …

Business Model Choice For Heavy Equipment Manufacturer, Philippe Blaettchen, Niyazi Taneri, Sameer Hasija

Research Collection Lee Kong Chian School Of Business

Technological advances enable new business models for heavy equipment manufacturers wherein customers access equipment without ownership. We seek to understand the profitability and environmental performance of different emerging business models in light of salient economic and operational factors. We develop a game-theoretic model to identify the optimal choice between a traditional ownership-based business model and two access-based models: servicization and peer-to-peer sharing. After-sales services, equipment characteristics, usage environments, and fuel prices affect this choice. We also provide a novel framework to analyze business models’ environmental impact, which incorporates trade-offs between economic value and environmental costs and shows that all models …

Parallel Degradome-Seq And Dms-Mapseq Substantially Revise The Mirna Biogenesis Atlas In Arabidopsis, Xingxing Yan, Changhao Li, Kaiye Liu, Tianru Zhang, Qian Xu, Xindi Li, Jiaying Zhu, Ziying Wang, Anikah Yusuf, Shuqing Cao, Xu Peng, James J Cai, Xiuren Zhang

Faculty, Staff and Student Publications

MicroRNAs (miRNAs) are produced from highly structured primary transcripts (pri-miRNAs) and regulate numerous biological processes in eukaryotes. Due to the extreme heterogeneity of these structures, the initial processing sites of plant pri-miRNAs and the structural rules that determine their processing have been predicted for many miRNAs but remain elusive for others. Here we used semi-active DCL1 mutants and advanced degradome-sequencing strategies to accurately identify the initial processing sites for 147 of 326 previously annotated Arabidopsis miRNAs and to illustrate their associated pri-miRNA cleavage patterns. Elucidating the in vivo RNA secondary structures of 73 pri-miRNAs revealed that about 95% of them …

A Comparative Study And Machine Learning Enabled Efficient Classification For Multispectral Data In Agriculture, Priyanka Gupta, Shruti Kanga, Varun Narayan Mishra

Baghdad Science Journal

Reliable and accurate crop maps are required for food security from regional to global scale. The increased availability of satellite imagery leads to a “Big Data” problem while producing crop maps. Now, cloud-based platforms have gained a lot of attention for crop classification over large regions. The main goal of the research is to analyze crop classification using various machine learning (ML) such as Support Vector Machine (SVM), Gradient Tree Boosting (GTB), Random Forest (RF), Decision Tree (DT) as well as Classification and Regression Trees (CART) on Google Earth Engine platform. The aim is to explore the Google Earth Engine’s …

Check Out The Library, 2024 Summer Issue, Cal Poly Humboldt Library

Library Publications

Issue 18

Light Em' Up, Lorna Renee Young

Theses and Dissertations

In this thesis I will document and explore my process from researching the show to putting it on stage. Theatre is different from concert lighting which I have experience in but lighting in a theatre capacity is still new and through every show I was able to learn something new. Through this program I have learned how to successfully take a script from the paperwork to the stage.

Three Essays On Environmental, Social, And Governance (Esg), Zhengwei Fu

Theses and Dissertations

This abstract synthesizes findings from three studies examining the impact of environmental, social, and governance (ESG). In essay one, using environmental regulatory enforcement data from EPA, I find that facility-level political connections are positively related to the likelihood of experiencing environmental regulatory enforcement. The effect is mainly driven by political connections related to Democratic senators. Consequently, politically connected facilities reduce their air pollution. The effect of political connection is diminished when the authority of senators over environmental regulatory enforcement becomes weaker after the 2017 presidential election. Heterogeneity analyses reveal that the impact of political connection is stronger in states with …

The Philosophy Of Incarceration And Punishment And Its Evolvement. Is It Enough?, Katherine Sebok

Capstone Projects – Politics and Government

This research project explores the evolution of incarceration philosophies and their disconnect from outdated prison infrastructure in the United States, with a focus on Illinois. From ancient civilizations’ reliance on retributive justice to the modern era’s emphasis on rehabilitation, punishment practices have evolved, yet many facilities remain stuck in the past. The “tough-on-crime” era deepened the divide, leading to overcrowding and neglect. While recent reforms prioritize rehabilitation, progress is hindered by outdated facilities. Illinois’ plans to demolish and rebuild Logan and Stateville Correctional Centers offer renewed hope, but the lengthy process requires significant investment and commitment from all involved parties.

Author Correction: Mediators Of Necroptosis: From Cell Death To Metabolic Regulation, Xiaoqin Wu, Laura E Nagy, Jérémie Gautheron

Faculty, Staff and Student Publications

No abstract provided.

The Role Of Occipital Condyle And Atlas Anomalies On Occipital Cervical Fusion Outcomes In Chiari Malformation Type I With Syringomyelia: A Study From The Park-Reeves Syringomyelia Research Consortium, Alexander T Yahanda, Joyce Koueik, Laurie L Ackerman, P David Adelson, Gregory W Albert, Philipp R Aldana, Tord D Alden, Richard C E Anderson, David F Bauer, Tammy Bethel-Anderson, Karin Bierbrauer, Douglas L Brockmeyer, Joshua J Chern, Daniel E Couture, David J Daniels, Brian J Dlouhy, Susan R Durham, Richard G Ellenbogen, Ramin Eskandari, Herbert E Fuchs, Gerald A Grant, Patrick C Graupman, Stephanie Greene, Jeffrey P Greenfield, Naina L Gross, Daniel J Guillaume, Todd C Hankinson, Gregory G Heuer, Mark Iantosca, Bermans J Iskandar, Eric M Jackson, George I Jallo, James M Johnston, Bruce A Kaufman, Robert F Keating, Nickalus R Khan, Mark D Krieger, Jeffrey R Leonard, Cormac O Maher, Francesco T Mangano, Jonathan Martin, J Gordon Mccomb, Sean D Mcevoy, Thanda Meehan, Arnold H Menezes, Michael S Muhlbauer, Brent R O'Neill, Greg Olavarria, John Ragheb, Nathan R Selden, Manish N Shah, Chevis N Shannon, Joshua S Shimony, Matthew D Smyth, Scellig S D Stone, Jennifer M Strahle, Mandeep S Tamber, James C Torner, Gerald F Tuite, Elizabeth C Tyler-Kabara, Scott D Wait, John C Wellons, William E Whitehead, Tae Sung Park, David D Limbrick, Raheel Ahmed

Faculty, Staff and Student Publications

Objective: Congenital anomalies of the atlanto-occipital articulation may be present in patients with Chiari malformation type I (CM-I). However, it is unclear how these anomalies affect the biomechanical stability of the craniovertebral junction (CVJ) and whether they are associated with an increased incidence of occipitocervical fusion (OCF) following posterior fossa decompression (PFD). The objective of this study was to determine the prevalence of condylar hypoplasia and atlas anomalies in children with CM-I and syringomyelia. The authors also investigated the predictive contribution of these anomalies to the occurrence of OCF following PFD (PFD+OCF).

Methods: The authors analyzed the prevalence of condylar …

Reproducibility Of Quantitative Myocardial Perfusion And Coronary Flow Capacity By Positron Emission Tomography: 3d Digital Silicon Photomultiplier Solid State Vs Legacy 2d Analogue Systems For Clinical Practice And Trials, Amanda Roby, Lindsey Harmon, Kelly Sander, Linh Bui, Danai Kitkungvan, Monica Patel, Jagat Narula, Nils P Johnson, K Lance Gould

Faculty, Staff and Student Publications

Aims: Quantitative rest-stress myocardial perfusion in millilitres per minute per gram among multiple 2D and 3D positron emission tomography-computed tomography (PET-CT) scanners is essential for personalized cardiac management and clinical trials. Accordingly, this study reports the accuracy and precision of quantitative rest-stress millilitres per minute per gram and coronary flow capacity among 2D and two different digital 3D silicon photomultiplier (SiPM) PET-CT scanners for quantifying the severity of coronary pathophysiology for clinical trials or guiding interventions vs. medical treatment.

Methods and results: One hundred seventy-one participants underwent 748 paired serial rest or stress PET perfusion imaging in the same person …

Use Of Ipsc-Derived Smooth Muscle Cells To Model Physiology And Pathology, Callie S Kwartler, Jose Emiliano Esparza Pinelo

Faculty, Staff and Student Publications

The implementation of human induced pluripotent stem cell (hiPSC) models has introduced an additional tool for identifying molecular mechanisms of disease that complement animal models. Patient-derived or CRISPR/Cas9-edited induced pluripotent stem cells differentiated into smooth muscle cells (SMCs) have been leveraged to discover novel mechanisms, screen potential therapeutic strategies, and model in vivo development. The field has evolved over almost 15 years of research using hiPSC-SMCs and has made significant strides toward overcoming initial challenges such as the lineage specificity of SMC phenotypes. However, challenges both specific (eg, the lack of specific markers to thoroughly validate hiPSC-SMCs) and general (eg, …

Endovascular Versus Medical Therapy In Posterior Cerebral Artery Stroke: Role Of Baseline Nihss Score And Occlusion Site, Davide Strambo, Patrik Michel, Thanh N Nguyen, Mohamad Abdalkader, Muhammad M Qureshi, Daniel Strbian, Christian Herweh, Markus A Möhlenbruch, Silja Räty, Marta Olivé-Gadea, Marc Ribo, Marios Psychogios, Urs Fischer, Anh Nguyen, Joji B Kuramatsu, David Haupenthal, Martin Köhrmann, Cornelius Deuschl, Jordi Kühne Escolà, Jelle Demeestere, Robin Lemmens, Lieselotte Vandewalle, Shadi Yaghi, Liqi Shu, Volker Puetz, Daniel P O Kaiser, Johannes Kaesmacher, Adnan Mujanovic, Dominique Cornelius Marterstock, Tobias Engelhorn, Manuel Requena, Hormuzdiyar H Dasenbrock, Piers Klein, Diogo C Haussen, Mahmoud H Mohammaden, Hend Abdelhamid, Lorena Souza Viana, Bruno Cunha, Isabel Fragata, Michele Romoli, Francesco Diana, Wei Hu, Chao Zhang, Pekka Virtanen, Riikka Lauha, Jessica Jesser, Judith Clark, Stavros Matsoukas, Johanna T Fifi, Sunil A Sheth, Sergio Salazar-Marioni, João Pedro Marto, João Nuno Ramos, Milena Miszczuk, Christoph Riegler, Sven Poli, Khouloud Poli, Ashutosh P Jadhav, Shashvat M Desai, Volker Maus, Maximilian Kaeder, Adnan H Siddiqui, Andre Monteiro, Hesham E Masoud, Neil Suryadareva, Maxim Mokin, Shail Thanki, Kemal Alpay, Pauli Ylikotila, James E Siegler, Italo Linfante, Guilherme Dabus, Negar Asdaghi, Vasu Saini, Christian H Nolte, Eberhard Siebert, Bettina L Serrallach, Charlotte S Weyland, Uta Hanning, Lukas Meyer, Anne Berberich, Peter A Ringleb, Raul G Nogueira, Simon Nagel

Faculty, Staff and Student Publications

Background: Acute ischemic stroke with isolated posterior cerebral artery occlusion (iPCAO) lacks management evidence from randomized trials. We aimed to evaluate whether the association between endovascular treatment (EVT) and outcomes in iPCAO acute ischemic stroke is modified by initial stroke severity (baseline National Institutes of Health Stroke Scale [NIHSS]) and arterial occlusion site.

Methods: Based on the multicenter, retrospective, case-control study of consecutive iPCAO acute ischemic stroke patients (PLATO study [Posterior Cerebral Artery Occlusion Stroke]), we assessed the heterogeneity of EVT outcomes compared with medical management (MM) for iPCAO, according to baseline NIHSS score (≤6 versus >6) and occlusion site …

The Beneficial Role Of Sunitinib In Tumor Immune Surveillance By Regulating Tumor Pd-L1, Vivian L Rose, Anaga Ajoy, Craig A Johnston, Gloria R Gogola, Pranav J Parikh

Faculty, Staff and Student Publications

Importance: There is a need for a pediatric hand function test that can be used to objectively assess movement quality. We have developed a toy-based test, the Bead Maze Hand Function (BMHF) test, to quantify how well a child performs an activity. This is achieved by assessing the control of forces applied while drawing a bead over wires of different complexity.

Objective: To study the psychometric properties of the BMHF test and understand the influence of age and task complexity on test measures.

Design: A cross-sectional, observational study performed in a single visit.

Setting: Clinical research laboratory.

Participants: Twenty-three participants …