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Decriminalizing Academia: Black First-Generation Community College Students In Unsatisfactory Academic Standing, Gerome Maurice Bell, Jr. Jul 2024

Decriminalizing Academia: Black First-Generation Community College Students In Unsatisfactory Academic Standing, Gerome Maurice Bell, Jr.

Educational Leadership & Workforce Development Theses & Dissertations

Community colleges serve as critical access points to higher education for Black students. However, current outcomes suggest that Black students are not being properly served in America’s community colleges. Although well-meaning institutional leaders often create policies and programs aimed at improving success rates for students from marginalized backgrounds, too often, the voices of those directly impacted by the policy are not considered. Consequently, little is known about the lived experiences of Black first-generation community college students, especially those in unsatisfactory academic standing. The purpose of this transcendental phenomenological study was to explore the lived experiences of Black first-generation students on …


Development Of A Conceptual Framework For Complex System Governance (Csg) Performance Measurement, James Hartwell Rutherford Jul 2024

Development Of A Conceptual Framework For Complex System Governance (Csg) Performance Measurement, James Hartwell Rutherford

Engineering Management & Systems Engineering Theses & Dissertations

Within the Complex System Governance (CSG) paradigm, system performance is regulated by nine metasystem governance functions, which provide control, communication, coordination, and integration. However, CSG has lacked a fully developed model or language to richly articulate system performance at a conceptual level. The purpose of this research was to develop a systems theory-based conceptual framework to measure the performance of CSG metasystem governance using an inductive research design.

Although ‘good performance’ may seem like an obvious idea, the current literature on performance measurement across many disciplines and contexts contains vastly inconsistent uses of the word ‘performance.’ Both researchers and practitioners …


Study Of Atypical Alarmone Synthesis In Clostridioides Difficile, Declan Nathaniel Butler Jul 2024

Study Of Atypical Alarmone Synthesis In Clostridioides Difficile, Declan Nathaniel Butler

Chemistry & Biochemistry Theses & Dissertations

Clostridioides difficile is a Gram-positive anaerobic bacterium that causes infections in humans that costs healthcare systems billions per year. C. difficile infection has high rates of recurrence due to multiple antibiotic resistance. When bacteria are in stressful environments, they produce hyperphosphorylated guanosine ribonucleotide signaling molecules called alarmones. The accumulation of alarmones activates the stringent response (SR), in which bacterial cells induce transcription of stress survival genes to delay growth and replication. The C. difficile SR is regulated by enzymatic activity of a bifunctional synthetase/hydrolase, RelA/SpoT homolog (RSH), and a monofunctional small alarmone synthetase (RelQ). Additionally, the SR is potentially regulated …


Sharps Injuries Among Healthcare Workers In Liberia And Ghana: A Cross-Sectional Survey, Laura Jean Ridge, John Arko-Mensah, Josh Lambert, Lydia Aziato, G. Clinton Zeantoe, Henry Ofori Duah, Marjorie Mccullagh Jul 2024

Sharps Injuries Among Healthcare Workers In Liberia And Ghana: A Cross-Sectional Survey, Laura Jean Ridge, John Arko-Mensah, Josh Lambert, Lydia Aziato, G. Clinton Zeantoe, Henry Ofori Duah, Marjorie Mccullagh

College of Nursing Faculty Research and Publications

There are little data on sharps injuries among healthcare workers in West Africa despite the region’s high rate of hepatitis B and human immunodeficiency virus. The purpose of this study is to investigate healthcare workers’ history of sharps injuries in Liberia and Ghana. An electronic cross-sectional survey was conducted among healthcare workers in Liberia and Ghana from February to June 2022. A link to the survey was texted to participants through professional association membership lists, including nursing, midwifery, and physician assistant organizations in both Liberia and Ghana and a physician organization in Ghana only. Five hundred and nine participants reported …


Attribute-Based Fine-Grained Access Control Using Verifiable Credentials, Srinivasa Dumpa Jul 2024

Attribute-Based Fine-Grained Access Control Using Verifiable Credentials, Srinivasa Dumpa

Student Theses

In the era of digital transformation, ensuring secure and privacy-preserving access control mechanisms is of paramount importance. Traditional identity-based access control systems often fall short in providing granular control and user autonomy over digital identities. This thesis presents a novel approach to access control by leveraging the power of verifiable credentials and attribute-based access control. The proposed system introduces a decentralized and user-centric framework that enables fine-grained access control based on specific attributes encapsulated within verifiable credentials. These tamper-evident digital credentials, stored in a user's digital wallet, contain a rich set of attributes that can be selectively disclosed to grant …


Tracing The Development Of Trust In Automation/Autonomy In A Multitasking Environment, Tetsuya Sato Jul 2024

Tracing The Development Of Trust In Automation/Autonomy In A Multitasking Environment, Tetsuya Sato

Psychology Theses & Dissertations

Future Advanced Air Mobility (AAM) operations will likely involve autonomous systems that exceed the capabilities of a typical automation. However, human operators could use such systems counterproductively by either misusing unreliable systems or disusing reliable systems. One determinant for inappropriate use of autonomous systems is trust. Human factors theorists proposed numerous ways to characterize trust such as the tripartite model of trust that describes the bases of trust in automation (i.e., performance, process, and purpose; Lee & See, 2004). Previous works have indicated that participants rated lower performance- and process-based trust toward the automation when the tracking task required more …


Young Driver Training And Socioeconomic Status: A Human-In-The-Loop Driving Simulator Evaluation, Jeffrey Edward Glassman Jul 2024

Young Driver Training And Socioeconomic Status: A Human-In-The-Loop Driving Simulator Evaluation, Jeffrey Edward Glassman

Psychology Theses & Dissertations

Previous research consistently shows that young drivers are poor at anticipating latent hazards on the roadway compared to more experienced drivers. The Road Awareness and Perception Training (RAPT) program is a driver training program that aims to accelerate young drivers’ learning of hazard anticipation (HA) skills. More recent research has started showing evidence that RAPT may be even more effective at reducing accidents for young drivers with a lower socioeconomic status (SES), though the direct impact of RAPT on HA skills in the driver population is yet unclear. The current experiment thus directly evaluated the effectiveness of RAPT on the …


Parallel-In-Time Implicit Schemes For Nonlinear Pdes, Subhash Paudel Jul 2024

Parallel-In-Time Implicit Schemes For Nonlinear Pdes, Subhash Paudel

Mathematics & Statistics Theses & Dissertations

An accurate prediction of unsteady physical phenomena arising in various applications (e.g., rotorcraft and turbomachinery flows, fluid-structure interaction, maneuvering flight conditions, etc.) requires a very large number of time steps, thus considerably increasing the total computational time, because conventional time integrators are inherently sequential. Parallel-in-time methods offer a promising direction for drastically reducing the computational time and achieving such scalability that is required for solving these unsteady problems on modern supercomputers with hundreds of thousands of computing cores. The parallel performance of existing parallel-in-time algorithms for nonlinear equations especially of the hyperbolic or mixed type is far from being satisfactory. …


Work-Life Balance Fantasy Logics Of Mothers Working In Community Colleges: A Glitch Methodology Using Intimate Inquiry And Aesthetic Mediation, Emily Hanson Moore Jul 2024

Work-Life Balance Fantasy Logics Of Mothers Working In Community Colleges: A Glitch Methodology Using Intimate Inquiry And Aesthetic Mediation, Emily Hanson Moore

Educational Leadership & Workforce Development Theses & Dissertations

This post-qualitative study explores work-life balance as a sustaining fantasy produced by neoliberal, patriarchal, productivity-driven systems and how this fantasy manifests affectively for mothers who work in community colleges. The study began by contextualizing the work-life balance fantasy within higher education as a gendered workscape. Using intimate inquiry (Laura, 2013) and aesthetic meditation as the primary approaches, the researcher engaged in conversations with participants about their experiences mothering and working in community colleges. The primary data sources were these conversations, participant artifacts, researcher self-reflection and artifacts, and a range of contemporary cultural texts including podcasts, poetry, television, social media posts …


Privacy-Preserving Deep Learning Framework For Iot Malware Detection, Sabbir Ahmed Khan Jul 2024

Privacy-Preserving Deep Learning Framework For Iot Malware Detection, Sabbir Ahmed Khan

Computer Science Theses & Dissertations

Cyberattacks on IoT devices are accelerating at an unprecedented rate, largely driven by IoT malware activities. The IoT malware attacks typically comprise three stages: intrusion, infection, and monetization. Existing IoT malware detection methods fail to identify malicious activities at the intrusion and infection stages and thus cannot stop potential attacks timely. In our research, we have leveraged power side-channel information as input to our deep learning model to identify malware at early stages of intrusion on IoT devices. But, deploying a resource-intensive deep learning model on highly resource-constrained IoT devices is a significant challenge. Consequently, utilizing a Machine Learning as …


A Strategic Communication Plan For The Clemente Center At Florida Tech, Cristiano Bozzolan Jul 2024

A Strategic Communication Plan For The Clemente Center At Florida Tech, Cristiano Bozzolan

Theses and Dissertations

This design project develops a strategic communication plan for the Clemente Center at the Florida Institute of Technology, aimed at enhancing campus engagement. The methodology includes interviews, focus groups, a SWOT analysis, and secondary data analysis, providing insights into the communication dynamics at the center.

Key findings reveal a reliance on outdated communication methods and insufficient use of digital platforms. The proposed communication plan introduces optimized digital signage, targeted email campaigns, community engagement initiatives, and enhanced staff training. These strategies are designed to be cost-effective and actionable, addressing the center's current limitations and leveraging opportunities for improved community interaction.

This …


Evaluating The Influence Of Evtol Pilot Interface Visual Density And Information Density On Pilot Situation Awareness, Workload, And Search Performance, Bhoomin Bhupendrabhai Chauhan Jul 2024

Evaluating The Influence Of Evtol Pilot Interface Visual Density And Information Density On Pilot Situation Awareness, Workload, And Search Performance, Bhoomin Bhupendrabhai Chauhan

Theses and Dissertations

The purpose of the current study was to investigate the influence of levels of visual density (VD) and information density (ID) of an electrical vertical take-off and landing (eVTOL) aircraft pilot interface on pilot situation awareness (SA), workload, and search performance. An eVTOL aircraft is a novel aircraft design that is able to perform vertical take-off and landing similar to a rotorcraft and transition to a forward flight, similar to a fixed-wing aircraft. These aircraft are envisioned to operate in urban environments at lower altitudes, necessitating efficient, clear, and concise pilot interfaces to ensure safety and operational effectiveness. The study …


Integration Analysis Of Nssm, Winlogon, And P2p Networks: Security Impact And Mitigation Strategies, Maisa Emneina Jul 2024

Integration Analysis Of Nssm, Winlogon, And P2p Networks: Security Impact And Mitigation Strategies, Maisa Emneina

Theses and Dissertations

In today's digital world, where everything is interconnected, new security threats are constantly emerging. This thesis explores the security risks that come from the combination of three specific technologies: Non-Sucking Service Manager (NSSM), Winlogon Helper DLLs, and Peer-to-Peer (P2P) networks. NSSM is a powerful tool for managing services, but it can also be used by attackers to find and exploit system weaknesses. Winlogon Helper DLLs are essential for the Windows logon process, making them a critical target for attacks. When you add P2P networks into the mix, which many applications use to share data, the potential for security issues increases …


Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler Jul 2024

Prolonged Quadriceps Latency During Gait Early After Anterior Cruciate Ligament Injury Predicts Radiographic Knee Osteoarthritis 6-Years After Anterior Cruciate Ligament Reconstruction, Naoaki Ito, Jacob J. Capin, Elanna Arhos, Elizabeth Wellsandt, Ryan T. Pohlig, Thomas S. Buchanan, Lynn Snyder-Mackler

Physical Therapy Faculty Research and Publications

The purpose was to explore quadriceps electromechanical function (quadriceps latency) during gait after anterior cruciate ligament injury as a predictor for radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction. Change in latency after preoperative physical therapy was also examined.

Methods

Quadriceps latency (time between peak knee moment and quadriceps electromyography) was calculated before preoperative physical therapy (2.4 [0.5–7.5] months after anterior cruciate ligament injury) and after preoperative physical therapy in 24 athletes. Participants were dichotomized into osteoarthritis (Kellgren and Lawrence grade ≥ 2) and non-osteoarthritis groups at 6-years. Forward selection logistic repression was performed using z-score normalized quadriceps latency …


Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand Jul 2024

Reduced Oxygen Desaturation In The Vastus Lateralis Of Chronic Stroke Survivors During Graded Muscle Contractions, Allison S. Hyngstrom, Jennifer N. Nguyen, Spencer A. Murphy, Stephanie C. Raab, Brian D. Schmit, David D. Gutterman, Matthew J. Durand

Physical Therapy Faculty Research and Publications

Background

Few studies have examined changes in skeletal muscle physiology post-stroke. This study examined changes in tissue oxygen saturation (StO2) of the vastus lateralis (VL) muscle of stroke survivors and age-matched control participants during maximal and submaximal isometric contractions of the knee extensor muscles.

Objectives

We hypothesized that tissue oxygen desaturation (ΔStO2) during knee extensor muscle contractions would be less in the VL in the paretic vs. the non-paretic and control legs.

Methods

Ten chronic stroke survivors (>6 months post-stroke) with lower extremity muscle weakness and 10 age-matched controls completed this prospective cohort study. Maximum …


Use Of Ultrasound For Identification Of Musculoskeletal Injury In Active Populations, Kathleen Karen Hogan Jul 2024

Use Of Ultrasound For Identification Of Musculoskeletal Injury In Active Populations, Kathleen Karen Hogan

Rehabilitation Sciences Theses & Dissertations

Lower extremity tendinopathies and fasciopathy conditions are prevalent amongst sedentary individuals,1,2 athletes,3,4 elite runners,5,6and military personnel7 and can lead to chronic disability and reduction in quality of life. 8,9 Both tendinopathy and fasciopathy are thought to be mechanical in nature and caused by acute or chronic overloading leading to a disruption in the uniformity of the soft tissue structure. Ultrasound imaging has gained popularity in the last decade among many sports medicine clinicians to gain information regarding tissue structure for musculoskeletal injury (MKSI) management. Ultrasound imaging allows for the evaluation of in-vivo structures and at …


An Exploratory Study On E-Learning Software Utilization Among Professional Instructional Designers In Virginia, Mark Richard Parsons Jul 2024

An Exploratory Study On E-Learning Software Utilization Among Professional Instructional Designers In Virginia, Mark Richard Parsons

STEMPS Theses & Dissertations

This master's thesis aims to explore the diverse landscape of e-learning software employed by professional instructional designers in Virginia to develop educational content. The study investigated the learning management systems and rapid authoring software, their utilization, the challenges and benefits associated with their usage, and future trends. By gaining insights into the preferences and practices of instructional designers, this research contributes to a deeper understanding of the dynamic field of e-learning software in the context of Virginia's educational landscape.


A Guide To Understanding Big Data For The Nurse Scientist: A Discursive Paper, Henry Ofori Duah, Samantha J. Boch, Sara Arter, Nichole Nidey, Joshua Lambert Jul 2024

A Guide To Understanding Big Data For The Nurse Scientist: A Discursive Paper, Henry Ofori Duah, Samantha J. Boch, Sara Arter, Nichole Nidey, Joshua Lambert

College of Nursing Faculty Research and Publications

Big data refers to extremely large data generated at high volume, velocity, variety, and veracity. The nurse scientist is uniquely positioned to leverage big data to suggest novel hypotheses on patient care and the healthcare system. The purpose of this paper is to provide an introductory guide to understanding the use and capability of big data for nurse scientists. Herein, we discuss the practical, ethical, social, and educational implications of using big data in nursing research. Some practical challenges with the use of big data include data accessibility, data quality, missing data, variable data standards, fragmentation of health data, and …


Inpatient Staff Perspective On Verbal De-Escalation Within A High Acuity Population, Giovanna Dezutti Jul 2024

Inpatient Staff Perspective On Verbal De-Escalation Within A High Acuity Population, Giovanna Dezutti

Dissertations

This study explored inpatient staff’s perspective of verbal de-escalation within a high acuity population as well as the factors that make either a positive or negative impact on the effectiveness of verbal de-escalation as used in high acuity impatient settings. This phenomenological study used semi-structured interviews of 5 participants working in this setting. Participants were recruited through snowball sampling, and interviews were conducted via zoom. This study found that participants unanimously agreed that the training they received regarding verbal de-escalation was not sufficient and that employment of certain personality traits and behaviors were more effective than using only the methods …


A Qualitative Study Exploring The Management & Implications Of Power Differentials Experienced By Pre-Licensed Supervisees In Clinical Supervision Settings, Joyti Jariwala Jul 2024

A Qualitative Study Exploring The Management & Implications Of Power Differentials Experienced By Pre-Licensed Supervisees In Clinical Supervision Settings, Joyti Jariwala

Dissertations

The focus in this qualitative study was to explore how power differentials in supervision create positive and negative experiences between licensed psychologists and pre-licensed doctoral students. The study results provide insight into how supervisees navigate these dynamics during supervision, which typically involves experiential learning environments in which trainees discuss progress, receive feedback, and enhance their skills. The theoretical framework grounding the study was social learning theory, which is based on the idea that individuals learn from modeling, observation, and imitation in a social context (Bandura, 1986). Reflexive thematic analysis was used to recognize similarities in findings gathered via two sets …


A Review Of Secondary Technology Education Teacher Needs In Virginia, M. Kathleen Ferguson Jul 2024

A Review Of Secondary Technology Education Teacher Needs In Virginia, M. Kathleen Ferguson

Educational Leadership & Workforce Development Theses & Dissertations

Technology education teachers can have varied pre-service training experiences, thus their needs for classroom support may vary greatly. Perkins V requires evidence-based research to justify the use of funding for professional development. This researcher sought to support Virginia’s secondary technology education teachers, professional organizations, and the Virginia Department of Education’s Technology Education Specialist by providing research to determine professional development needs. This three-phase qualitative study used a survey, documents review, and focus groups to triangulate data to provide information about the research questions. The research questions focused on teachers’ educational background, technology program goals, and issues specific to secondary technology …


Bracketed Assessments In Behavioral Gerontology: Evaluating Preference With Present And Absent Stimuli, Flavia Eduarda Del Castillo Troche Jul 2024

Bracketed Assessments In Behavioral Gerontology: Evaluating Preference With Present And Absent Stimuli, Flavia Eduarda Del Castillo Troche

Theses and Dissertations

The present study evaluated the use of bracketed assessments to assess the activity preference of three individuals with dementia. The study proposed an alternative method to traditional stimulus preference assessments, to bridge the gap in behavior analytical literature within behavioral gerontology. Thus, bracketed assessments were conducted using two presentation methods, verbal plus visual presentation and verbal-only presentation. Results suggested that while participants showed consistency within low preferred activity selection in the bracketed assessment, variability was observed among participants’ preferences for high and moderate preferred activities. Both presentation methods yield similar selection results for one participant, however, the other two participants …


Cultural Selection Of Ethical Self-Control Toward Sustainability, Michael Jonathan Passage Jul 2024

Cultural Selection Of Ethical Self-Control Toward Sustainability, Michael Jonathan Passage

Theses and Dissertations

This study consisted of three experiments to improve our understanding of the conditions that foster cooperation related to sustainability. In Experiment 1, participants completed a demographic questionnaire and an environmental and social discounting task. Results (a) support the utility of the environmental discounting task; (b) suggest responding to the discounting task is dissimilar; and (c) show that responding to hypothetical consequences on the social discounting task correlates to actual responding. Experiment 2 evaluated whether interlocking behavioral contingencies (by microculture members) associated with sustainable and non-sustainable aggregate products (Condition A & B) could be selected by cultural consequences (i.e., 20¢ toward …


Causes And Consequences Of Mitotic Chromosome Missegregation In Human Pluripotent Stem Cells, Chenhui Deng Jul 2024

Causes And Consequences Of Mitotic Chromosome Missegregation In Human Pluripotent Stem Cells, Chenhui Deng

Dartmouth College Ph.D Dissertations

Mitosis is a fundamental process that ensures the equal distribution of replicated chromosomes, which carry an organism's genetic material, into two daughter cells. The fidelity of mitosis is paramount, as errors in chromosome segregation result in aberrant chromosome numbers, including gains or losses, a state termed aneuploidy. Aneuploidy impacts a broad range of human conditions, including being one of the major hurdles in early human development where it is the primary cause of miscarriages and birth defects. Strikingly, more than 70% of human preimplantation embryos are aneuploid with mitotic chromosome segregation errors being the most common source of aneuploidy. However, …


Dna-Delivered Monoclonal Antibodies Targeting The P53 R175h Mutant Epitope Inhibit Tumor Development In Mice, Dafei Chai, Xu Wang, Praveen Neeli, Shan Zhou, Xingfang Yu, Kanaga Sabapathy, Yong Li Jul 2024

Dna-Delivered Monoclonal Antibodies Targeting The P53 R175h Mutant Epitope Inhibit Tumor Development In Mice, Dafei Chai, Xu Wang, Praveen Neeli, Shan Zhou, Xingfang Yu, Kanaga Sabapathy, Yong Li

Faculty, Staff and Students Publications

The tumor suppressor p53 is the most common mutated gene in cancer, with the R175H as the most frequent p53 missense mutant. However, there are currently no approved targeted therapies or immunotherapies against mutant p53. Here, we characterized and investigated a monoclonal antibody (mAb) that recognizes the mutant p53-R175H for its affinity, specificity, and activity against tumor cells in vitro. We then delivered DNA plasmids expressing the anti-R175H mAb or a bispecific antibody (BsAb) into mice to evaluate their therapeutic effects. Our results showed that the anti-R175H mAb specifically bound to the p53-R175H antigen with a high affinity and …


Triticale As A Source Of Resistance To Wheat Streak Mosaic Virus And Triticum Mosaic Virus, Marcos Winicius Goncalves De Souza Jul 2024

Triticale As A Source Of Resistance To Wheat Streak Mosaic Virus And Triticum Mosaic Virus, Marcos Winicius Goncalves De Souza

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Wheat streak mosaic virus (WSMV) and Triticum mosaic virus (TriMV) present a great threat to wheat production in the Great Plains area of the United States due to the loss of photosynthetic area causing reductions in crop yields. Effective control of these viruses is limited to a few available strategies including controlling volunteer wheat and using currently identified resistant genes to both the vector and viruses. While effective, these genes show temperature sensitivity and yield drag, and evidence that the vectors and viruses can overcome them has been found. Thus, new methods of genetic resistance are urgently needed. Field observations …


Preferential Crystallization Of (±)-Pinenyllithium·Tmeda, Alexander N. Erickson, Curtis Haltiwanger, Masoumeh Rahim, Charles M. Garner Jul 2024

Preferential Crystallization Of (±)-Pinenyllithium·Tmeda, Alexander N. Erickson, Curtis Haltiwanger, Masoumeh Rahim, Charles M. Garner

Chemistry Faculty Research and Publications

(±)-Pinenyllithium·TMEDA or (tetra­methyl­ethylenedi­amine-κ2N,N′)(η3-6,6-di­methyl-2-methylenebi­cyclo­[3.1.1]hept­yl)lithium, [Li(C10H15)(C6H16N2)], is readily pre­pared from β-pinene, butyl­lithium and TMEDA, and the racemic material pre­fer­entially crystallizes even from 96:4 (92% ee) mixtures of (−)- and (+)-β-pinene, respectively. The structure is monomeric, with the geminal-dimethyl bridge of the bicyclic structure shielding one face of the allyl system, restricting the lithium to the opposite face and preventing the Li–all­yl–Li aggregation observed with some other allyl­lithium systems. The symmetry of the allyl system, bond lengths, bond angles and out-of-plane deviations …


Utilization Of Probiotics To Compete With Clostridioides Difficile For Nutrient-Niches In A Variety Of In Vitro Contexts, April Elizabeth Johnson Jul 2024

Utilization Of Probiotics To Compete With Clostridioides Difficile For Nutrient-Niches In A Variety Of In Vitro Contexts, April Elizabeth Johnson

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Clostridium difficile is a major threat to public health and primarily affects at risk groups such as elderly, immunocompromised individuals, and individuals on antibiotics. Many decades of research have been conducted to figure out ways to exclude or reduce C. difficile colonization and toxin production. Two major proposed mechanisms for colonization resistance are production of secondary bile salts and competition for nutrients.

In Chapter 2, we found that antibiotic treatment disrupted bile salt metabolism increasing the levels of the primary bile salt cholate and decreasing the levels of deoxycholate, a secondary bile salt. However, bile salts were not required …


Growth And Simulation Of Dielectric-Metal Nanoheterostructured Thin Films By Ballistic Deposition, Shawn Wimer Jul 2024

Growth And Simulation Of Dielectric-Metal Nanoheterostructured Thin Films By Ballistic Deposition, Shawn Wimer

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This thesis is divided into two related topics: the structural and chemical characterization of dielectric-metal nanoheterostructured thin films grown by glancing angle deposition (GLAD) and the results of the simulated growth of films and structures by GLAD with discrete-space and continuous-space Monte Carlo ballistic simulation.

Individual structures comprising films grown by GLAD were investigated by S/TEM and SEM imaging, electron diffraction, and chemical characterization and mapping by EDX. Different intermolecular interactions within and between different materials, including Si, Ag, Au, and ZrO2, are linked to differences in the shapes of individual materials in heterostructures, the shape of heterostructures …


Pdrs4all Viii. Mid-Infrared Emission Line Inventory Of The Orion Bar, Dries Van De Putte, Raphael Meshaka, Boris Trahin, Emilie Habart, Els Peeters, Olivier Berné, Felipe Alarcón, Amélie Canin, Ryan Chown, Ilane Schroetter, Ameek Sidhu, Christiaan Boersma, Emeric Bron, Emmanuel Dartois, Javier R. Goicoechea, Karl D. Gordon, Takashi Onaka, Michael Kaufman, For Full Author List, See Comments Below Jul 2024

Pdrs4all Viii. Mid-Infrared Emission Line Inventory Of The Orion Bar, Dries Van De Putte, Raphael Meshaka, Boris Trahin, Emilie Habart, Els Peeters, Olivier Berné, Felipe Alarcón, Amélie Canin, Ryan Chown, Ilane Schroetter, Ameek Sidhu, Christiaan Boersma, Emeric Bron, Emmanuel Dartois, Javier R. Goicoechea, Karl D. Gordon, Takashi Onaka, Michael Kaufman, For Full Author List, See Comments Below

Faculty Research, Scholarly, and Creative Activity

Context. Mid-infrared emission features are important probes of the properties of ionized gas and hot or warm molecular gas, which are difficult to probe at other wavelengths. The Orion Bar photodissociation region (PDR) is a bright, nearby, and frequently studied target containing large amounts of gas under these conditions. Under the “PDRs4All” Early Release Science Program for JWST, a part of the Orion Bar was observed with MIRI integral field unit (IFU) spectroscopy, and these high-sensitivity IR spectroscopic images of very high angular resolution (0.2′′) provide a rich observational inventory of the mid-infrared (MIR) emission lines, while resolving the H …