Digital Commons Network^™

Genome-Wide Association Study For Ashy Stem Blight Resistance In Usda Common Bean Germplasm, Ainong Shi, Deigo M. Viteri, Angela M. Linares-Ramirez, Haizheng Xiong, Senyu Chen

Horticulture Faculty Publications and Presentations

Ashy stem blight (ASB), caused by the fungus Macrophomina phaseolina (Tassi) Goidanich, poses a significant threat to common bean (Phaseolus vulgaris L.) cultivation worldwide. Due to the limited effectiveness of fungicides against ASB, the development of genetically resistant cultivars offers an eco-friendly and sustainable management strategy. This study aimed to accelerate genetic improvement in common bean by integrating molecular breeding tools with conventional breeding approaches to enhance ASB resistance. A total of 335 common bean germplasm accessions from the United States Department of Agriculture (USDA) Germplasm Resources Information Network (GRIN) collection were evaluated for their response to the PRI21 M. …

A Review Of Mirvetuximab Soravtansine-Gynx In Folate Receptor Alpha-Expressing Platinum-Resistant Ovarian Cancer, Judith A Smith, Patrick Medina, Mary Miao, Kathleen N Moore

Faculty, Staff and Student Publications

Purpose: To evaluate the pharmacology, efficacy, safety, and dosing and administration considerations (including adjusted ideal body weight [AIBW] dosing) for mirvetuximab soravtansine-gynx, a first-in-class folate receptor alpha (FRα)-directed antibody-drug conjugate for platinum-resistant ovarian cancer (PROC).

Summary: A literature search was conducted in PubMed using the terms "ovarian cancer" and "mirvetuximab soravtansine" of articles published from inception to April 16, 2024. Relevant publications, abstracts, and clinical trials were reviewed. Mirvetuximab soravtansine-gynx is dosed at 6 mg/kg AIBW every 3 weeks and comprises an FRα-binding antibody, a hydrophilic disulfide linker, and a maytansinoid DM4 payload. Mirvetuximab soravtansine-gynx binds to FRα, which induces …

In Vivo Crispr Activation Screen Identifies Acyl-Coa-Binding Protein As A Driver Of Bone Metastasis, Hongqi Teng, Qinglei Hang, Caishang Zheng, Yuelong Yan, Shaomin Liu, Yang Zhao, Yalan Deng, Litong Nie, Weiche Wu, Marisela Sheldon, Zachary Yu, Wei Shi, Jianxuan Gao, Chenling Meng, Consuelo Martinez, Jie Zhang, Fan Yao, Yutong Sun, Di Zhao, Boyi Gan, Tong Meng, Li Ma

Faculty, Staff and Student Publications

One of the most common sites of cancer metastasis is to the bone. Bone metastasis is associated with substantial morbidity and mortality, and current therapeutic interventions remain largely palliative. Metastasizing tumor cells need to reprogram their metabolic states to adapt to the nutrient environment of distant organs; however, the role and translational relevance of lipid metabolism in bone metastasis remain unclear. Here, we used an in vivo CRISPR activation screening system coupled with positive selection to identify acyl-coenzyme A (CoA) binding protein (ACBP) as a bone metastasis driver. In nonmetastatic and weakly metastatic cancer cells, overexpression of wild-type ACBP, but …

Investigating The Impact Of A Social Media Literacy Intervention On Appearance Satisfaction, Life Satisfaction, And Affect, Jennifer Lai

Student Theses and Dissertations

Social media (SM) platforms are popular mediums for entertainment and connection among young adults, and the companies behind these platforms have intentionally designed and implemented features to enhance user engagement. Research has identified a negative relationship between SM use and mental health outcomes but few studies have tested SM literacy interventions to reduce the impact of SM use on these outcomes. To extend the literature on SM literacy interventions, this study sought to investigate the impact of a digitally-delivered SM literacy intervention on appearance satisfaction, life satisfaction, and affect. Participants were 125 students (M_Age = 20.50; SD = 2.79; …

Rhythm Rescue: Gamification To Reinforce Electrocardiogram Strip Knowledge, Katie Roman Msn, Ccrn, Tammy Lis Msn, Rn-Bc, Ccrn, Npd-Bc

Nursing

Electrocardiogram (ECG) strip interpretation and subsequent intervention is a crucial concept for nurses as it plays a vital role in providing safe and effective patient care. Modern learners seek the opportunity for on demand and interactive educational opportunities. Literature demonstrates that integrating gamification in education increases learner knowledge, interest, and engagement. Current technology leveraged to develop an interactive, self-paced case study game to promote rhythm identification and intervention. Pictures of supplies used in practice and a video of mock defibrillation were utilized to reinforce understanding. Scenarios unfolded as the learner progressed. Incorrect answers directed nurses back to the question to …

Participant 012: Reiki Master With Three Months Of Experience (Asian American & White; Female; New York, Usa)

0885: Reiki and Well-Being Interviews

This is an interview about Reiki and its connection with overall well-being with a Reiki Master holding three months of experience (Asian American & White; Female; New York, USA). She was interviewed on May 21, 2025. The participant agreed to the terms outlined in the verbal informed consent form before this interview. Some of the broad conversations during this interview include the full circle moments of finding aspects of spirituality as a young adult, but revising it when you're older; her first experience with a Reiki session being during her Reiki I attunement; Reiki's place in helping participant find self-love …

Correction: Targeting Of Epigenetic Co-Dependencies Enhances Anti-Aml Efficacy Of Menin Inhibitor In Aml With Mll1-R Or Mutant Npm1, Warren Fiskus, Christopher P Mill, Christine Birdwell, John A Davis, Kaberi Das, Steffen Boettcher, Tapan M Kadia, Courtney D Dinardo, Koichi Takahashi, Sanam Loghavi, Michael J Soth, Tim Heffernan, Gerard M Mcgeehan, Xinjia Ruan, Xiaoping Su, Christopher R Vakoc, Naval Daver, Kapil N Bhalla

Faculty, Staff and Student Publications

No abstract provided.

Sharc: Simulator For Hardware Architecture And Real-Time Control, Paul K. Wintz, Yasin Sonmez, Paul Griffioen, Mingsheng Xu, Surim Oh, Heiner Litz, Ricardo G. Sanfelice, Murat Arcak

Faculty Work Comprehensive List

Tight coupling between computation, communication, and control pervades the design and application of cyber-physical systems (CPSs). Due to the complexity of these systems, advanced design procedures that account for these tight interconnections are paramount to ensure the safe and reliable operation of control algorithms under computational constraints. This paper presents the Simulator for Hardware Architecture and Real-time Control (Sharc) to assist in the co-design of control algorithms and the computational hardware on which they are run. Sharc simulates the execution of a user-specified control algorithm on a given processor microarchitecture configuration, evaluating how computational constraints affect the dynamical properties of …

Turning Analysis Into Action: Opportunities And Challenges In Implementing Wastewater Science For Public Health Decision-Making, Anna Gitter, Valeria Ruvalcaba, Katelyn Clark, Theresa Tran Carapucci, Fuqing Wu, Blake M Hanson, Jennifer Deegan, John Balliew, Eric Boerwinkle, Anthony W Maresso, Kristina D Mena

Faculty, Staff and Students Publications

In the 5 years since the emergence of the COVID-19 pandemic, the field of wastewater-based epidemiology (WBE) has dramatically expanded with programs implemented across the globe to monitor for SARS-CoV-2 and other viruses of public health concern. However, the best way to use wastewater surveillance data and inform local communities of the utility of wastewater science remains limited and sporadically discussed. Specifically, there is vague guidance regarding interpreting varying levels of viral loads in wastewater for public health significance. While collaborative efforts are key to implementing these community-specific wastewater surveillance programs, effectively using the data for public health decision-making still …

Tax Trends, Nicholas J. Fiore

Tax Adviser

No abstract provided.

Tax Clinic, Michael S. Wolff

Tax Adviser

No abstract provided.

Taxation Of Computer Technology, Robert L. Black, Craig E. Reese

Tax Adviser

No abstract provided.

Tax Trends, Nicholas J. Fiore

Tax Adviser

No abstract provided.

Life Insurance Company Taxation: Prospects For Change, Gary M. Winkle

Tax Adviser

No abstract provided.

Tax Clinic, William T. Diss

Tax Adviser

No abstract provided.

Decision Approach To Acrs, Earl F. Davis, Caroline D. Strobel

Tax Adviser

No abstract provided.

[2025 Honorable Mention] Pedagogies In The Flesh And Recovery Of Historical Memory From The Perspective Of A Salvadoreña, Janelle I. Martinez

Ethnic Studies Research Paper Award

My submission is a praxis paper. First, I explore the concepts and theories I would like to put into praxis, which are pedagogies in the flesh and recovery of historical memory. I then explain how and why I put them into praxis.

Do We Really Need A Femininemenon?: The Gendered Context Of Congress And Women’S Representation, Hannah Scholen

Honors Program: Senior Projects (Public)

Does the changing gendered context of Congress affect women’s representation? The literature shows that women are more likely than men to prioritize and introduce issues that have a distinct impact on women, such as education and health, and that women’s power as a minority group changes when their numbers grow. With the growing number of women in Congress, it’s crucial to understand how that increase affects Congresswomen. I use the Center for Effective Lawmaking’s Legislative Effective Score methodology, focusing on the education and health Issue Area LES’, and run interaction regressions to study the relationship between gender and legislative effectiveness, …

Are All Criminals The Same? The ‘Ndrangheta & The Penitentiary Law System, Andrea Miceli

Ohio Northern University International Law Journal

No abstract provided.

Striking A Balance: Teachers’ Strikes In Guyana And The United States, Camilla Leonard, Claire O'Brien

Ohio Northern University International Law Journal

No abstract provided.

Why Legalism Failed, Aaron J. Walayat Esq.

Ohio Northern University International Law Journal

No abstract provided.

Best Practice For Managing Ai & Academic Integrity In Writing Assignments, Jordan Canzonetta

May Institute

No abstract provided.

Investigating The Role Of Lysophosphatidic Acid Receptor 3 In Ocular Surface Ion Transport And Fluid Secretion, Ethan Lindgren

Natural Sciences and Mathematics | Biological Sciences Master's Theses

Dry eye disease (DED) is a multifactorial disease that drives tear film instability and hyperosmolarity, directly damaging the ocular surface epithelium. Lysophosphatidic acid receptor (LPAR) is a G-protein coupled receptor (GPCR) responsible for Ca²⁺ and cAMP mobilization via PLC and adenylyl cyclase activation, respectively. LPAR signaling is involved in cell proliferation and wound healing in human corneal epithelial cells (HCECs) as well as in neuropathic pain. This study aims to investigate expression and functional roles of LPAR3 in ocular surface. Ocular surface potential difference (OSPD) and tear fluid volume measurements were performed in mice with topically applied LPAR modulators. …

The National Labor Relations Act Patch Notes: Recent Changes To The Federal Employment Law Landscape, Its Impact On Esport Players, And What These Changes Indicate About The Future, Emet Mah

The Journal of Business, Entrepreneurship & the Law

This Note explores this possibility of esports players unionizing, and exercising their rights under the National Labor Relations Act. Part II provides background on the esport industry as a business and its evolution over time. Part III outlines some of the major issues affecting the esport industry, particularly focusing on the lack of player representation. Part IV examines the industry’s current use of player associations and will explore their shortcomings, prompting the need for formal unionization. Part V will cover the benefits of unionization and how esport players might come under the coverage of the NLRA.

Shackles Or Safeguards?: Tailoring Ndas And Noncompetes To Protect Interests Without Imposing Uniform Restraints, Nadia Brenden

The Journal of Business, Entrepreneurship & the Law

To better understand the implications of the FTC’s sweeping proposal and the need for a state-by-state approach, the following sections dive into the legal, historical, and comparative foundations of restrictive covenants, trace their evolution across jurisdictions, and explain why states—not federal agencies—are best positioned to strike the right balance. Part II provides an overview of legal doctrines governing the transmission of proprietary information, a history of the early applications of employment contracts, and a comparative analysis of international noncompete standards. Part III describes how different jurisdictions apply trade secret, contract, and employment law to protect business interests through enforceable agreements. …

Tax Trends, Nicholas J. Fiore

Tax Adviser

No abstract provided.

Tax Clinic, Henry J. Ferrero Jr.

Tax Adviser

No abstract provided.

The Tax Adviser, Volume 15, Number 11, November 1984, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Tax Trends, Nicholas J. Fiore

Tax Adviser

No abstract provided.

Washington Report: Aicpa Testifies On Generation-Skipping Transfer Tax Proposals, Kenneth F. Thomas, William R. Stromsem

Tax Adviser

No abstract provided.