Digital Commons Network^™

Protective Multi-Stressor Interactions In The Anthropocene: Key Considerations For Investigating Cross-Tolerance In A Conservation Context, Essie M Rodgers, Simone Baldanzi, Michael Collins, W Wesley Dowd, Lauric Feugere, Giovanna Mottola, Fanny Vermandele, Daniel F Gomez Isaza

School of Biological and Marine Sciences

In the Anthropocene, species are increasingly faced with multiple stressors that are more severe and less predictable than before. While multiple stressors often interact to affect organisms negatively, sometimes these interactions can be beneficial, enhancing resilience through cross-protection. Cross-protection interactions occur when exposure to one stressor, such as elevated temperature, enhances an organism’s tolerance to a different stressor, like hypoxia, through shared protective mechanisms or signaling pathways. Understanding the potential for cross-protection to combat rapid and diverse environmental change is crucial for conservation, as it potentially alters the predicted consequences of such change. Here, we outline 10 key considerations for …

Optimal Treatment Duration In Metastatic Renal Cell Carcinoma Patients Responding To Immune Checkpoint Inhibitors: Should We Treat Beyond Two Years?, Alexander Decruyenaere, Gennigens Christine, Rottey Sylvie, Laenen Annouschka, Emmanuel Seront, Els Everaert, Philip R Debruyne, Heidi Van Den Bulck, Julie Bastin, Verbiest Annelies, Christof Vulsteke, Peter Schatteman, Daisy Luyten, Sandrine Aspeslagh, Nieves Martinez-Chanza, Marlies De Bock, Thomas Meyskens, Jolanda Verheezen, Barbara Brouwers, Benoit Beuselinck

School of Nursing and Midwifery

BACKGROUND AND PURPOSE: Optimal treatment duration is unknown in metastatic renal cell carcinoma (mRCC) responding to immune checkpoint inhibitors (ICPIs). Prolonged treatment can lead to late toxicity, burden for day clinics and financial impact.

PATIENTS AND METHODS: This multicenter retrospective study included mRCC patients responding to ipilimumab/nivolumab in first-line or nivolumab in later lines, who were treated for at least 21 months and did not stop for toxicity. Progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS) were modeled non- and semi-parametrically. The effect of elective ICPI discontinuation (i.e. treatment interruption at the clinician's discretion) between 21 and 25 …

Lanskap Linguistik Di Taman Literasi Martha Christina Tiahahu, Jakarta Selatan, Suryani Indrastuti, Sri Munawarah

Multikultura

Taman Literasi Martha Christina Tiahahu (TLMCT) is a tourist attraction located in South Jakarta that has been established since 1948. As a tourist attraction, TLMCT has signages and facility markers to facilitate visitors to find and utilize the facilities at the park. Those signs use code preference, inscription, and emplacement to maximize the information delivery. The formulation of the problem in this research is how the code preference, inscription, and emplacement of linguistic landscape (LL) at TLMCT. This research aims to explain the code preference, inscription, and emplacement of LL at TLMCT. Quantitative and qualitative methods were used in this …

A Novel, Metal-Based Approach To Identify Residences With Lead Service Lines, Danielle Land, Grant D. Brown, David M. Cwiertny, Marc A. Edwards, Mona Hanna, Drew E. Latta, Michelle M. Scherer

Michigan Tech Publications

There is an urgent need for rapid, cost-effective approaches to identify residences with lead service lines (LSLs). We evaluated whether analyzing water for corrosion-related metals could accurately identify residences with LSLs without relying on potentially inaccurate property records. We applied principal component analysis logistic regression (PCA-LR) and classification tree models using 28 analytes per bottle (including Pb, Cu, Zn, Fe, Al, and others) measured in 216 water samples collected in Flint, Michigan, in August 2015. The PCA-LR model achieved 87% accuracy (AUROC = 0.93) with 81% sensitivity and 90% specificity, while the classification tree model achieved 80% accuracy (AUROC = …

Gene Regulatory Network Prediction Using Machine Learning, Deep Learning, And Hybrid Approaches, Sai Teja Mummadi, Md Khairul Islam, Victor Busov, Hairong Wei

Michigan Tech Publications

Construction of gene regulatory networks (GRNs) is essential for elucidating the regulatory mechanisms underlying metabolic pathways, biological processes, and complex traits. In this study, we developed and evaluated machine learning, deep learning, and hybrid approaches for constructing GRNs by integrating prior knowledge and large-scale transcriptomic data from Arabidopsis thaliana, poplar, and maize. Among these, hybrid models that combined convolutional neural networks and machine learning consistently outperformed traditional machine learning and statistical methods, achieving over 95% accuracy on the holdout test datasets. These models not only identified a greater number of known transcription factors regulating the lignin biosynthesis pathway but also …

Revisiting The Post-Tsunami Aceh School: A Community-Based Evaluation Framework For Improving Build Back Better Projects, Muhammad Naufal Fadhil, Aji Sofiana Putri, Muhammad Fadli Muslimin

ASEAN Journal of Community Engagement

This study proposes a community-based evaluation framework to assess and improve the existing conditions of post-tsunami schools based on the occupants’ evaluations. Rapid, donor-driven reconstruction often defaults to ‘fit-for-all’ solutions that bypass community needs, resulting in facilities that are misaligned with local contexts. This project focused on Lampageu State Elementary School in Banda Aceh, Indonesia, which was reconstructed in 2009 by a German NGO after the 2004 tsunami. The project began by observing the school’s physical condition through the community engagement team, followed by a review and exploration of the school’s design needs with the school community. The community-based evaluation …

Saving Halloren: Driving International Business Success Through Proper Practices And Strategy, Paul J. Collins

Undergraduate Honors Theses

In an increasingly globalized world, navigating cultural differences is crucial to success in international business. This paper examines the application of cultural international business principles through a case study of Halloren Chocolate, Germany’s oldest chocolate factory. Using Erin Meyer’s Eight-Scale Tool for Mapping Cultural Differences, the study addresses the challenges that Darren Elhert, a Canadian businessman, faced while course-correcting the factory.

The paper analyzes how Halloren’s traditional, Eastern German culture hindered its ability to compete in the modern global marketplace. The case study focused on Elhert’s efforts to revive a stagnant company culture while preserving its national heritage. Through primary …

Russia And The War In Ukraine: Three Critical Myths, Nicholas Kiersey

Political Science Faculty Publications

Though often framed as a conflict between an autocratic regime and a liberal democracy, the Russo-Ukrainian War also represents a direct challenge to the post-1989 global order and its cosmopolitan norms. Paradoxically, many Critical International Relations (IR) theorists—once skeptical of Western militarism—now align with liberal interventionist responses to the war. Drawing on Cunliffe’s concept of the “utopianism of unipolarity,” this article argues that Critical IR has embraced a reductive “good war” narrative that casts Ukraine as a virtuous subaltern state resisting Russian imperialism, while dismissing left critiques as denials of Ukrainian “agency.” In doing so, Critical IR reproduces cultural myths …

Adaptive Crop Switching For Irrigated Agriculture In Response To Climate Change In The Western U.S., Shahryar Fazli, Wenzhao Li, Surendra Maharjan, Rejoice Thomas, Aqil Tariq, Hesham El-Askary

Mathematics, Physics, and Computer Science Faculty Articles and Research

Adaptive irrigation strategies are crucial for balancing water use, economic viability, and food security in the arid Western United States. However, as a key indicator vital in regulating agricultural productivity and crop irrigation, water use efficiency (WUEc) is becoming increasingly complex to estimate due to climate change. This study explores the critical role of key meteorological drivers, such as maximum temperature (tmax) and vapor pressure deficit (vpd), and their impacts on crop-specific WUEc. Future impacts are also assessed through integrating machine learning models with climate projections from the CMIP6 framework under SSP2–4.5 and SSP5–8.5 scenarios to forecast WUEc trends from …

Dynamic Analysis And Fatigue Life Evaluation Of Single Herringbone Planetary Gear System With Crack Fault, Dongping Sheng, Jie Yang, Chun Su

Journal of Mechanical Engineering Science and Technology (JMEST)

The herringbone planetary gear transmission is widely used due to its exquisite compact structure, excellent load-bearing capacity, and stable transmission characteristics. However, root crack is one of the most common failure modes of gears. A cracked herringbone planetary gear system is taken as research object. The sun gear with crack fault is studied from the aspect of modal and transient dynamic analysis, and the related results are compared with the healthy gear. Based on the transient dynamic analysis of the herringbone teeth with cracks, a fatigue life evaluation is conducted. Firstly, the results show that no significant difference between the …

Impact Of Print Speed And Nozzle Temperature On Tensile Strength Of 3d Printed Abs For Permanent Magnet Turbine Systems, Wirawan Wirawan, Hilmi Iman Firmansyah, Satworo Adiwidodo, Mohammad Sukri Mustapa

Journal of Mechanical Engineering Science and Technology (JMEST)

Operational parameters must be integrated into turbine systems' main components, which are determined by turbine systems' functional requirements. The need for producing component designs more effectively raises the possibility of using additive manufacturing. The study focuses on the optimization of the mechanical properties of the principal components of magnetic turbines manufactured with 3D printers using Acrylonitrile Butadiene Styrene (ABS), by changing the temperature and speed of the nozzle. The approach consisted of modeling a standard test piece in CAD software and producing ABS-based test pieces using a 3D printer with print speeds of 50, 70, 90, and 110 mm/s and …

Finite Element Analysis Of The Construction Strength Of Semi-Submarine Glass-Bottom Catamaran, Berliana Ayarent Puteri, Aldias Bahatmaka, Widya Aryadi, Musdika Bagas Satria Putrananda, Christian Imanuel Hutagalung

Journal of Mechanical Engineering Science and Technology (JMEST)

Indonesia's extraordinary marine tourism potential requires innovation in how to enjoy it. This study discusses the innovative design of a semi-submarine glass-bottom ship for the development of marine tourism in Indonesia, which allows tourists to enjoy the beauty of the underwater world safely and comfortably. This catamaran is designed with two hulls that provide high stability and optimal deck area for tourism needs. The study focuses on analyzing the ship's frame structure using the finite element analysis method, especially on using sandwich panels that combine wood and carbon fiber materials to achieve the optimal combination of structural strength, weight, and …

Associations Between School-Based Arrests And High School Graduation Status Of African American Female Students In Florida, Rannisha Missick

Walden Dissertations and Doctoral Studies

Zero tolerance school discipline policies, originally intended to address serious threats such as weapon and drug possession, have increasingly been applied to minor behavioral infractions, disproportionately affecting African American students, particularly females. These exclusionary practices, including school-based arrests, have been linked to adverse educational outcomes. The purpose of this quantitative correlational study was to examine associations between school-based arrests due to zero tolerance policy violations and high school graduation status of African American female students in Florida. The study was guided by the intersectionality theory, which posits individuals who belong to multiple marginalized groups experience compounded forms of discrimination. Archival …

Toxicological And Environmental Assessment Of Trace And Heavy Metals In Harnoi Coal Deposits, Abbottabad, Khyber Pakhtunkhwa, Pakistan, Muhammad Sajid, Shaukat Khan, Muhammad Kashif, Khan Amir Khan, Muhammad Junaid

Jurnal Pendidikan Geografi: Kajian, Teori, dan Praktek dalam Bidang Pendidikan dan Ilmu Geografi

Mining and burning of coal release various toxic substances that can contaminate both surface and groundwater, thereby posing significant risks to human health, especially for households located near mines, coal deposits, or coal-fired power stations. This research examines the environmental effects of coal mining in the Harnoi Region of Abbottabad, Khyber Pakhtunkhwa, Pakistan. Four mining sites were randomly selected within the study area, and eight coal samples were collected and analyzed using atomic absorption spectrophotometry to determine the concentrations of trace and heavy metals. The findings indicate that Harnoi coal contains elevated concentrations of arsenic, zinc, lead, cadmium, nickel, cobalt, …

Staff Education On Culturally Tailored Hispanic Diabetes Management In A Primary Care Community Clinic, Robyn Elizabeth Reeves

Walden Dissertations and Doctoral Studies

The Hispanic population is the fastest-growing ethnic minority in the United States, and they have a 66% chance of developing Type 2 diabetes mellitus (T2DM). Less than half of Hispanic patients with diabetes achieve optimal glycemic control due to cultural barriers and dietary issues. At the project site, a primary care practice in the southeastern United States regarding cultural competency training in diabetes management for Hispanics was identified. The practice-focused question was: Does providing education to primary care staff improve their knowledge of diabetes management among Hispanic patients with diabetes, as evidenced by pre- and post-surveys? In the project, I …

Equal Access To Justice: A Case Study Of Eviction Victims Without Legal Aid And Post Criminality In Houston, Texas., Okanlawon Jamiu Akinwonmi

Walden Dissertations and Doctoral Studies

The unending increase in eviction rates and existing housing problems in the United States of America is not an exaggeration. Heterogeneity of requirements or eviction laws is a pervasive phenomenon across the states nationwide. These fundamental issues require immediate attention and must be addressed. The purpose of this study is to explore the dynamic gap in our criminal justice system, the lack of legal aid, and potential criminality resulting from eviction and housing problems. Moreover, the psychological, physical, and emotional effects of these problems on the victims in relation to the roles of social workers, community advocates, and housing policy …

A Qualitative Case Study Exploring The Decision-Making Criteria Of Policymakers In The State Of Michigan To Reinstate A Universal Helmet Law, Eberley Nicole Adams

Walden Dissertations and Doctoral Studies

Policymakers are elected to create, amend, or repeal legislation that impacts public welfare; however, little is known about the specific criteria used when making public health and safety decisions, particularly regarding motorcycle helmet laws. In 2012, Michigan repealed its universal helmet law (UHL) after 35 years, replacing it with a partial helmet law specifying requirements for helmetless riding. Despite an increase in unhelmeted fatalities, the UHL has not been reinstated, raising questions about the legislative decision-making process. Prior research has found that factors such as budgeting, statistical data, interest groups, education, income, political stability, and public opinion may guide these …

Breaking The Cycle Of Burnout In Financial Aid, Ashlee Thayer

Masters Projects

The purpose of this project is to explore the causes and effects of burnout in financial aid staff and what potential strategies could be implemented to support staff experiencing burnout. Lack of work-life balance and increased work-related stress are a few causes of burnout seen throughout the literature. The intention of this project is to create a workshop that provides managers and directors with the necessary tools to identify the sign of burnout in their employees and provide the necessary support to mitigate the effects of burnout. Addressing and preventing burnout in financial aid staff will increase staff retention and …

2020-10-06 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-01-26 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-04-27 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-05-11 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Dissecting Macrophage Metabolism In Metabolic Liver Disease, Mandy Mei-Ying Chan

Arts & Sciences Graduate Student Theses and Dissertations

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common cause of chronic liver disease around the globe; however, the mechanisms that lead to the progression of metabolic liver disease are poorly understood. Liver-resident macrophages, known as Kupffer cells (KCs), are the largest population of macrophage in the human body, playing a critical role in immune sensing and tissue homeostasis. In the context of MASLD, KCs undergo cell death through an unclear mechanism, and monocytes enter the liver where they differentiate into macrophages. Next-generation sequencing and spatial-omics studies have revealed significant, heterogeneity in the recruited macrophage populations in both human …

Predicted Inelastic Response Of Conventional And Ductile Steel Concentrically Braced Frame Buildings Under Wind Loads, Conrad Hamblin Belshe

Theses and Dissertations

The inelastic response of three-story steel concentrically braced frame buildings under wind loads was simulated to determine the applicability of ductile braced frame design to wind load applications. This study examined three types of steel concentrically braced frames: a conventional braced frame, a ductile braced frame, and a ductile braced frame with a reduced beam requirement. Braced frames were designed for four design wind speeds (220 mph, 156 mph, 127 mph, and 110 mph), for a total of nine unique braced frame designs. Nonlinear static pushover analysis was used to determine system overstrength and ductility under wind loads. Eigenvalue vibration …

2021-03-09 Leadership Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

2021-04-06 Executive Council Minutes, Susie Salazar

Executive Council Minutes

No abstract provided.

Data-Driven Approach To Dynamic Resting State Functional Connectivity In Post-Traumatic Stress Disorder: An Enigma-Pgc Ptsd Study, Jacklynn M. Fitzgerald

Psychology Faculty Research and Publications

Using functional magnetic resonance imaging (fMRI), symptoms of posttraumatic stress disorder (PTSD) have been associated with aberrations in brain networks in the absence of a given cognitive demand or task, called resting-state networks. Prior work has focused on disruption in the static functional connectivity (FC) among specific regions constrained by a priori hypotheses. However, dynamic FC, an approach that examines brain network characteristics over time, may provide a more sensitive measure to understand the network properties underlying dysfunction in PTSD. Further, using a data-driven analytic approach may reveal the contribution of other larger network disturbances beyond those revealed by hypothesis-driven …

A Comprehensive Review On Machine Learning-Based Job Recommendation Systems, Shaymaa Al-Juboori, Su-Cheng Haw, Rui Ern Yap

School of Engineering, Computing and Mathematics

A dynamic, constantly shifting labor market creates enormous job postings, overwhelming candidates and making it difficult for businesses to find quality candidates. It is also hard for job seekers to find suitable jobs. Addressing these issues, machine learning-driven job recommender systems have recently become an essential tool using predictivemodels to improve the match between jobs and candidates. A hybrid design that combine scollaborative filtering with content-based filtering andadds contextual information like geographic location,industry trends, and user behavioural data can enhance the accuracy and relevance of recommendations. This paper reviews and critically analyzes contemporary jobre commender system techniques. The focus is …

Collection Of Instructional Slides From Molten Salt Electrochemistry Symposium (Moses), Devin Rappleye, Carlos Mejia

Faculty Publications

During the Molten Salt Electrochemistry Symposium (MoSES) on July 30-31, 2025, interactive instruction was given to the attendees including live demonstrations. These slides contain the introductory instructions given for each learning module at MoSES 2025. Please visit https://pyro.byu.edu/moses for more information.

A Survey Of Image Forensics: Exploring Forgery Detection In Image Colorization, Saurabh Agarwal, Deepak Sharma, Nancy Girdhar, Cheonshik Kim, Ki-Hyun Jung

School of Engineering, Computing and Mathematics

In today’s digital era, the rapid evolution of image editing technologies has brought about a significant simplification of image manipulation. Unfortunately, this progress has also given rise to the misuse of manipulated images across various domains. One of the pressing challenges stemming from this advancement is the increasing difficulty in discerning between unaltered and manipulated images. This paper offers a comprehensive survey of existing methodologies for detecting image tampering, shedding light on the diverse approaches employed in the field of contemporary image forensics. The methods used to identify image forgery can be broadly classified into two primary categories: classical machine …