Digital Commons Network^™

Practical Objectivity: Keeping Natural Science Natural, Alan G. Padgett

Faculty Publications

No abstract provided.

Boesenbergia Rotunda: From Ethnomedicine To Drug Discovery, T. Eng-Chong, L. Yean-Kee, C. Chin-Fei, H. Choon-Han, W. Sher-Ming, C.T. Li-Ping, F. Gen-Teck, Norzulaani Khalid, N. Abd Rahman, S.A. Karsani, S. Othman, R. Othman, R. Yusof

Research Publications (2011 to 2015)

Boesenbergia rotunda is a herb from the Boesenbergia genera under the Zingiberaceae family. B. rotunda is widely found in Asian countries where it is commonly used as a food ingredient and in ethnomedicinal preparations. The popularity of its ethnomedicinal usage has drawn the attention of scientists worldwide to further investigate its medicinal properties. Advancement in drug design and discovery research has led to the development of synthetic drugs from B. rotunda metabolites via bioinformatics and medicinal chemistry studies. Furthermore, with the advent of genomics, transcriptomics, proteomics, and metabolomics, new insights on the biosynthetic pathways of B. rotunda metabolites can be …

Studies Directed To The Development Of Long Lived Palladium Membranes For Hydrogen Purification, William Glenn Pinson

Graduate Student Theses, Dissertations, & Professional Papers

The focus of this study was to systematically investigate the variables involved in electroless deposition of palladium and palladium alloy membranes on a known porous stainless steel substrate, and apply the results to a new and novel porous stainless steel substrate. Different oxide pore and surface treatments were studied. The effect of silica as a diffusion barrier, surface pore modifier, and palladium nucleation site was examined. Silica sol-gel coating treated stainless steel substrates were explored. Several different formulas of sol-gel coatings and their impact on palladium and palladium copper deposition were researched. The roles of sintering and annealing and their …

Structured Dna Probe Microarrays For Detection Of Acetotrophic Methanogens In Complex Solutions, Jonas Boateng

Dissertations

No abstract provided.

Age As A Factor In Inter-Tissue Spacing Of Stable Carbon Isotope Values In Juvenile Human Remains From The Dakhleh Oasis, Egypt, Annie Laurie Norris

Electronic Theses and Dissertations

Although stable isotope analysis is routinely utilized in bioarchaeology and relies on principles that are well-understood, there are still fundamental issues that have not been thoroughly investigated. This thesis examines the relationship between inter-tissue spacing of carbon stable isotope values (δ13C) and age in juvenile human remains. Analyses of tissues within the same individual reveal disparate isotopic values for a variety of physiological and biological reasons discussed herein. This project examines the distance between the δ13C values in bone collagen, skin, hair, and nail, and examines how these distances vary between different age groups, utilizing data collected from 52 well-preserved …

Designing Direct And Indirect Factor Xa Inhibitors, Rami Al-Horani

Theses and Dissertations

Anticoagulants are the basis for treatment and prevention of thrombotic diseases. The currently available medicines are associated with a wide range of adverse reactions that mandates developing new anticoagulants. Several lines of evidence support the superiority of factor Xa (FXa) as a promising target to develop novel anticoagulants. This work focuses on the design of direct and indirect FXa inhibitors using an interdisciplinary approach. As indirect FXa inhibitors, a focused library of tetrasulfated N–arylacyl tetrahydroisoquinoline (THIQ) nonsaccharide allosteric antithrombin activators was designed, synthesized, and biochemically evaluated to establish their structure–activity relationship (SAR). An N–arylacyl THIQ analog having carboxylate at position–3, …

Evaluation Of A Wide Rim Phosphorylated Calix[4]Arene's Properties As A Sensory Molecule In An Er(Iii)-Pvc Membrane Sensor, Abbas Ali Zamani, Massoumeh Parinejad, Fataneh Jamali, Mohammad Reza Yaftian, Dominique Matt

Turkish Journal of Chemistry

This study concerns the evaluation of ionophoric properties of a functionalized calix[4]arene, named 5,17-bis(diphenylphosphinoyl)- 25,26,27,28-tetrapropoxycalix[4]arene (Calix), by its application as a sensing material in an erbium(III)-PVC membrane potentiometric sensor. A membrane formed by 30% PVC, 65% dioctyl phthalate (DOP) as plasticizing solvent mediator, 2% sodium tetraphenyl borate (NaTPB) as ion excluder, and 3% of Calix as ionophore shows the best performance of the sensor. The prepared sensor presents a nearly Nernstian response (a slope of 20.0 \pm 0.5 mV/decade) over a concentration range of 1 \times 10^{-7}--1 \times 10^{-3} M of erbium ions, with a limit of detection of 3.8 …

Mole Street Journal, November 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

A Century Of Chemistry Instruction At The College In Arlington: 1895-1995 (A Memoir And Scrapbook), Thomas James Cogdell

Chemistry & Biochemistry Faculty Publications - Archive

No abstract provided.

Homoploid Hybrid Speciation In A Rare Endemic Castilleja From Idaho (Castilleja Christii, Orobanchaceae), Danielle Leigh Clay

Boise State University Theses and Dissertations

Evidence to support the origins of a putative hybrid species with certainty must be determined using several lines of evidence: the presence of genetic additivity of parental marker alleles in a putative hybrid species, along with ecological or niche separation. Novel or transgressive morphological traits obtained through chromosomal rearrangements during hybridization may facilitate niche separation of the hybrid species from progenitor habitats. These evolutionary processes together enforce reproductive isolation and promote an independent evolutionary trajectory in hybrid species. By studying these evolutionary processes in putative hybrid species, researchers may identify hybrid species with confidence.

We employed multiple lines of evidence …

Mole Street Journal, October 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Remote Explosive Scent Tracing Rest, Gichd

Global CWD Repository

Remote Explosive Scent Tracing (REST) is essentially a survey methodology based on using dogs and rats to remotely detect landmines and explosive remnants of war (ERW). Systems similar to REST have been used in technical survey and mine clearance operations for 20 years, and have been subject to a study conducted by the Geneva International Centre for Humanitarian Demining (GICHD) since 2000.

At that time, REST was considered one of the most promising avenues for speeding up demining operations and making them more cost-efficient, very much in the spirit of the land release concept. The GICHD got involved in the …

Mole Street Journal, September 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Mole Street Journal, August 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Ferritin Diversity: Mechanistic Studies, Disease Implications, And Materials Chemistry, Robert Joseph Hilton

Theses and Dissertations

The study of ferritin includes a rich history of discoveries and scientific progress. Initially, the composition of ferritin was determined. Soon, it was shown that ferritin is a spherical, hollow protein. Eventually, over several decades of research, the structure and some function of this interesting protein was elucidated. However, the ferritin field was not completely satisfied. Today, for example, researchers are interested in refining the details of ferritin function, in discovering the role of ferritin in a variety of diseases, and in using ferritin for materials chemistry applications. The work presented in this dissertation highlights the progress that we have …

Mole Street Journal, July 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Remote Explosive Scent Tracing Of Explosive Remnants Of War: A Perspective From The 2010 Morogoro Workshop, Brent (Max) Jones, Rune Fjellanger, Christophe Cox, Alan Poling

The Journal of Conventional Weapons Destruction

In March 2010, a workshop was held in Morogoro, Tanzania, to consider the past, present and future status of the Remote Explosive Scent Tracing system for explosive- remnants-of-war detection. This article summarizes the workshop’s discussions and explains lessons learned from the REST research project in Morogoro.

Mole Street Journal, June 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Polyanhydride Microparticles Enhance Dendritic Cell Antigen Presentation And Activation, Maria P. Torres, Jennifer H. Wilson-Welder, Senja K. Lopac, Yashdeep Phanse, Brenda Carillo-Conde, Amanda E. Ramer-Tait, Bryan H. Bellaire, Michael J. Wannemeuhler, Balaji Narasimhan

Department of Food Science and Technology: Faculty Publications

The present studies were designed to evaluate the adjuvant activity of polyanhydride microparticles prepared in the absence of additional stabilizers, excipients, or immune modulators. Microparticles composed of varying ratios of either 1,6-bis(p-carboxyphenoxy)hexane (CPH) and sebacic acid (SA) or 1,8-bis(p-carboxyphenoxy)-3,6-dioxaoctane (CPTEG) and CPH were added to in vitro cultures of bone marrow-derived dendritic cells (DCs). Microparticles were efficiently and rapidly phagocytosed by DCs in the absence of opsonization and without centrifugation or agitation. Within 2 h, internalized particles were rapidly localized to an acidic, phagolysosomal compartment. By 48 h, only a minor reduction in microparticle size was …

The Effectiveness Of Process Oriented Guided Inquiry Learning To Reduce Alternate Conceptions In Secondary Chemistry, Michelle Jones Barthlow

Doctoral Dissertations and Projects

A nonequivalent, control group, pretest-posttest design was used to investigate student achievement in secondary chemistry. This study investigated the effect of process oriented guided inquiry learning (POGIL) in high school chemistry to reduce alternate conceptions related to the particulate nature of matter versus traditional lecture pedagogy. Data were collected from chemistry students in four large high schools and analyzed using ANCOVA. The results show that POGIL pedagogy, as opposed to traditional lecture pedagogy, resulted in fewer alternate conceptions related to the particulate nature of matter. Male and female students in the POGIL group posted better posttest scores than their traditional …

Effect Of Freshman Chemistry On Student Performance In Sophomore Engineering Courses, Michael A. Collura, Shannon Ciston, Nancy Ortins Savage

Chemistry and Chemical Engineering Faculty Publications

The role of first year chemistry courses in engineering programs varies somewhat across programs and disciplines. Clearly most engineering majors will encounter chemistry topics of a general nature in some of their upper-level course work. The purpose of requiring chemistry in the first year, however, goes well beyond learning chemical concepts. As a quantitative science, chemistry requires the use of math, principally algebra, on a regular basis in solving various problems. Students should gain an appreciation of the importance of units in solving problems should come to understand the difference between implicit and explicit properties and should develop other quantitative …

Mole Street Journal, May 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Otterbein Towers Summer 2011, Otterbein Towers

Towers Magazine

How a Re-Imagined Curriculum is shaping Otterbein’s Future. Features: How a Re-Imagined Curriculum is shaping Otterbein’s Future; Historical Highlights of Curriculum; Encore Careers; From Nurse to Pastry Chef & Entrepreneur; La Dolce Vita; 2011 Alumni Weekend, etc.

Mole Street Journal, April 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Student Researchers Share Project Results At April 8 Poster Show, Winthrop University

Winthrop News 2011

• Twenty-three students presented their research at the April 8 poster show in Sims Science Building.
• Topics ranged from High Mobility Group A1 Proteins, fungal spores, design/synthesis of Sphingosine Kinase Inhibitors and more.

Mole Street Journal, March 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Unh Scientists Helping Noaa Probe Winter Air Chemistry Mystery, David Sims

Media Relations

No abstract provided.

Mole Street Journal, February 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

Mole Street Journal, January 2011, University Of Arkansas, Fayetteville. Dept. Of Chemistry And Biochemistry

Mole Street Journal

No abstract provided.

The Hemocompatibility Of A Nitric Oxide Generating Polymer That Catalyzes S-Nitrosothiol Decomposition In An Extracorporeal Circulation Model, Terry C. Major, David O. Brant, Charles P. Burney, Kagya Amoako, Gail M. Annich, Mark E. Meyerhoff, Hitesh Handa, Robert E. Bartlett

Mechanical and Industrial Engineering Faculty Publications

Nitric oxide (NO) generating (NOGen) materials have been shown previously to create localized increases in NO concentration by the catalytic decomposition of blood S-nitrosothiols (RSNO) via copper (Cu)-containing polymer coatings and may improve extracorporeal circulation (ECC) hemocompatibility. In this work, a NOGen polymeric coating composed of a Cuo-nanoparticle (80 nm)-containing hydrophilic polyurethane (SP-60D-60) combined with the intravenous infusion of an RSNO, S- nitroso-N-acetylpenicillamine (SNAP), is evaluated in a 4 h rabbit thrombogenicity model and the anti-thrombotic mechanism is investigated. Polymer films containing 10 wt.% Cuo-nanoparticles coated on the inner walls of ECC circuits are employed concomitantly with systemic SNAP administration …