Digital Commons Network^™

Ethno-Conservation Of New Guinea Singing Dog Among Tribes In Pegunungan Tengah, Papua, Indonesia, Arni Syawal, Satyawan Pudyatmoko, Lies Rahayu Wijayanti Faida, Elieser Viktor Sirami, Esti Gesang Setyadi, Pratita Puradyatmika, Rendy Enggar Suwandi, Muhammad Ali Imron

Forest and Society

Interactions between humans and carnivores have been range from positive to negative, occasionally leading to human-wildlife conflict in many parts of the world. While dogs have roles to support humans, wild dogs such as wolf, dingoes, and singing dogs have both potential positive and negative roles for humans. We gathered knowledge among tribes in Pegunungan Tengah of Papua, Indonesia on their interactions with the New Guinea Singing Dog (NGSD) using an ethno-conservation approach. We conducted in-depth interviews using both emit and etic approaches with informants from the Amungme, Damal, Moni and Dani (Lani) tribes, who live in the habitat of …

Impact And Mitigation Measures Of Covid-19 Towards Food Security Through Participation In Forest Management By Community In Sook, Keningau District, Sabah, Vilaretti Atin, Walter Lintangah

Forest and Society

The COVID-19 pandemic has significantly impacted food security for the people due to the imposition of stringent measures to halt the spread of COVID-19 transmission. This study aimed to measure the community's perception of the level of COVID-19 impacts on their food security and to identify the community's participation in forest management around the Forest Management Unit (FMU) in Sook, Keningau District of Sabah, to improve their livelihood. A mixed-method approach was conducted where a total of 122 respondents were sampled using a questionnaire survey, focus group discussion with communities, and expert interviews to gather more valuable data. The result …

Docosahexaenoic Acid Stability In Ready-To-Use Therapeutic Food, Genevieve James, Kevin Stephenson, Meghan Callaghan-Gillespie, Mohamed Tabita Kamara, Hui Gyu Park, J Thomas Brenna, Mark J Manary

2020-Current year OA Pubs

Ready-to-use therapeutic food (RUTF) is used to treat young children diagnosed with severe acute malnutrition. RUTF with low and balanced linoleic and alpha-linolenic acid, plus omega-3 docosahexaenoic acid (DHA), supports long-term cognitive recovery. DHA is prone to degradation due to peroxidation, possibly exacerbated by the iron inherently in RUTF. Our goals were to prepare benchtop and manufacturing scale of RUTF formulations that include DHA and measure its retention. Twenty-seven RUTF formulas with base ingredients, including oats, high oleic or commodity peanuts, and encapsulated or oil-based DHA at various levels were prepared at benchtop scale, followed by seven months of climate-controlled …

A Cdh3-Β-Catenin-Laminin Signaling Axis In A Subset Of Breast Tumor Leader Cells Control Leader Cell Polarization And Directional Collective Migration, Priscilla Y Hwang, Jairaj Mathur, Yanyang Cao, Jose Almeida, Jiayu Ye, Vasilios Morikis, Daphne Cornish, Maria Clarke, Sheila A Stewart, Amit Pathak, Gregory D Longmore

2020-Current year OA Pubs

Carcinoma dissemination can occur when heterogeneous tumor and tumor-stromal cell clusters migrate together via collective migration. Cells at the front lead and direct collective migration, yet how these leader cells form and direct migration are not fully appreciated. From live videos of primary mouse and human breast tumor organoids in a 3D microfluidic system mimicking native breast tumor microenvironment, we developed 3D computational models, which hypothesize that leader cells need to generate high protrusive forces and overcome extracellular matrix (ECM) resistance at the leading edge. From single-cell sequencing analyses, we find that leader cells are heterogeneous and identify and isolate …

A Molecular Switch Between Mammalian Mll Complexes Dictates Response To Menin-Mll Inhibition, Yadira M Soto-Feliciano, Francisco J Sánchez-Rivera, Florian Perner, Douglas W Barrows, Edward R Kastenhuber, Yu-Jui Ho, Thomas Carroll, Yijun Xiong, Disha Anand, Alexey A Soshnev, Leah Gates, Mary Clare Beytagh, David Cheon, Shengqing Gu, X Shirley Liu, Andrei V Krivtsov, Maximiliano Meneses, Elisa De Stanchina, Richard M Stone, Scott A Armstrong, Scott W Lowe, C David Allis

Faculty, Staff and Student Publications

Menin interacts with oncogenic MLL1-fusion proteins, and small molecules that disrupt these associations are in clinical trials for leukemia treatment. By integrating chromatin-focused and genome-wide CRISPR screens with genetic, pharmacologic, and biochemical approaches, we discovered a conserved molecular switch between the MLL1-Menin and MLL3/4-UTX chromatin-modifying complexes that dictates response to Menin-MLL inhibitors. MLL1-Menin safeguards leukemia survival by impeding the binding of the MLL3/4-UTX complex at a subset of target gene promoters. Disrupting the Menin-MLL1 interaction triggers UTX-dependent transcriptional activation of a tumor-suppressive program that dictates therapeutic responses in murine and human leukemia. Therapeutic reactivation of this program using CDK4/6 inhibitors …

Identification Of Collaborative Cross Mouse Strains Permissive To Salmonella Enterica Serovar Typhi Infection, Kishore Alugupalli, Sudeep Kothari, Matthew P Cravens, Justin A Walker, Darren T Dougharty, Gregory S. Dickinson, Louis A Gatto, Andreas J Bäumler, Tamding Wangdi, Darla R Miller, Fernando Pardo-Manuel De Villena, Linda D Siracusa

Department of Microbiology and Immunology Faculty Papers

Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice. The Collaborative Cross (CC) is a large panel of recombinant inbred strains which has a wider range of genetic diversity than laboratory inbred mouse strains. We found that the CC003/Unc and CC053/Unc strains are permissive to intraperitoneal but not oral route of S. Typhi infection and show histopathological changes characteristic of human typhoid. These CC strains are immunocompetent, …

Using Innovative Copper‑Loaded Activated Alumina (Cu/Aa) As The Catalyst For Catalytic Wet Peroxidation (Cwpo) Of Catechol, Vijayalakshmi Gosu, Archana Dhakar, Tian C. Zhang, Rao Y. Surampalli, Verraboina Ubbaramaiah

Department of Civil and Environmental Engineering: Faculty Publications

In this study, copper-loaded activated alumina (Cu/AA) was synthesized and used for the CWPO of catechol (a representative refractory organic pollutant). Various characterization techniques were deployed to characterize the catalysts, e.g., activated alumina (AA), as well as pristine and spent 1% Cu/AA. The innovative 1% Cu/AA catalyst exhibited good thermal stability up to 1173 K with a marginal weight loss of 13%. The Cu species were well dispersed on the activated alumina framework with no significant cluster formation. Typically, the average copper particle size of 5 nm was dispersed on the AA framework. Catechol removal was observed to be 92% …

New Types Of Topologies And Neutrosophic Topologies, Florentin Smarandache

Neutrosophic Systems with Applications

In this paper, we recall the six new types of topologies that we introduced in the last years (2019-2022), such as: Refined Neutrosophic Topology, Refined Neutrosophic Crisp Topology, NeutroTopology, AntiTopology, SuperHyperTopology, and Neutrosophic SuperHyperTopology.

Editorial: What Does Not Kill You Makes You Stronger: Interactions Between Environmental Stresses And Microbial Virulence, Liang Wang, Ling-Jun Zhan, Michael J. Wise

Research outputs 2022 to 2026

The intriguing sit-and-wait hypothesis predicts that “virulence should be positively correlated with durability in the external environment because high durability reduces the dependence of transmission on host mobility” (Walther and Ewald, 2004) (Figure 1). Since the hypothesis was first proposed in the late 20th century (Ewald, 1983), both theoretical and computational studies have been reporting the relationships between environmental durability and microbial virulence (Sundberg et al., 2014; Wang et al., 2017, 2018, 2019a,b, 2020; Rafaluk-Mohr, 2019; Li et al., 2021) [...].

Book Review: In The Shadow Of The Palms: More-Than-Human Becomings In West Papua. Sophie Chao. Duke University Press, 2022, Carter Beale

Forest and Society

In the Shadow of the Palms offers a haunting and novel perspective on themes of dispossession and alienation wrought by the expansion of oil palm agribusiness in Indonesia. Drawing on fieldwork with a Marind community in the Upper Bian in West Papua, the text endeavors to describe such dispossessory dynamics from an embodied Marind ontology. Meticulous descriptions of interactions with various animal and plant species evidence a profound intersubjectivity of human and environment in the Marind world. Moreover, these encounters with multi-species entanglements often reveal how the Marind accommodate and assimilate the spiritual and material incursions inflicted by expanding oil …

Will Indigenous Ecological Knowledge Vanish? Assessing Persistence Of The Celako Kemali In Farming Practices Among The Serawainese In Bengkulu, Indonesia, Panji Suminar

Forest and Society

Indonesia is home to many indigenous peoples who can preserve the environment through their traditions amid the increasing of external values ​​and lifestyles’ penetration. The following presents the indigenous ecological knowledge of the Serawai people in the form of the celako kemali. Based on insights from the Indigenous research methods, this study aims first to assess the persistence of the celako kemali as a method for farming practices. Second, to identify transmission patterns of the celako kemali among generations in the Serawai community. This study found that there were 19 types of celako kemali. The current analysis demonstrates …

Living Through Crises Due To Successive Commodity Booms And Busts: Investigating The Changing Peasants' Farming Style In Rural Indonesia, Muchlas Dharmawan Tualle, A. Mujetahid, Muhammad Dassir, Nurhady Sirimorok, A. Khalid Muhammad, Andi Vika Faradiba Muin, Aryo Dwi Prasetyo

Forest and Society

This study aims to explain how a peasant community makes decisions in response to recurring crises in order to maintain their farms, and the extent to which vulnerability contexts and (external) institutions influence peasants’ decision-making regarding their livelihoods. In doing so, we present a case study of the Village of Ranga, in the South Sulawesi Province, Indonesia, where data collected through semi-structured interviews, observation, and Focus Group Discussion (FGD). Data regarding farmers' livelihood strategies in responding to the crises, in the form of commodity booms and busts, is analyzed by employing a sustainable rural livelihoods framework, while a Chayanovian “balance” …

Full Issue: Winter 2014

DePaul Magazine

DePaul professors produce a documentary TV series highlighting impoverished communities globally and those who have come to their aid. Also, learn how DePaul's Steans Center implements service learning that broadens academics and supports the university's Vincentian mission, discover out-of-the-box teaching methods employed by innovative faculty, and meet an alumnus who's one of the music industry's most prominent sound engineers.

Full Issue: Summer 2015

DePaul Magazine

No abstract provided.

Not A Waste: Wastewater Surveillance To Enhance Public Health, Anna Gitter, Jeremiah Oghuan, Anuja Rajendra Godbole, Carlos A. Chavarria, Carlos Monserrat, Tao Hu, Yun Wang, Anthony W. Maresso, Blake M. Hanson, Kristina D. Mena, Fuqing Wu

Pharmacy Faculty Articles and Research

Domestic wastewater, when collected and evaluated appropriately, can provide valuable health-related information for a community. As a relatively unbiased and non-invasive approach, wastewater surveillance may complement current practices towards mitigating risks and protecting population health. Spurred by the COVID-19 pandemic, wastewater programs are now widely implemented to monitor viral infection trends in sewersheds and inform public health decision-making. This review summarizes recent developments in wastewater-based epidemiology for detecting and monitoring communicable infectious diseases, dissemination of antimicrobial resistance, and illicit drug consumption. Wastewater surveillance, a quickly advancing Frontier in environmental science, is becoming a new tool to enhance public health, improve …

The Axillary View Typically Does Not Contribute To Decision Making In Care For Proximal Humeral Fractures, Alfadl A Abdulfattah, Hanan A Jawkhab, Altaf A Alhazmi, Nada A Alfaifi, Maryam A Sultan, Rajaa A Alnami, Nada Y Kenani, Shorooq A Hamzi, Shahd M Abu Sharha, Ibrahim M Dighriri

Faculty, Staff and Student Publications

Background: Helicobacter pylori (H. pylori) is a severe infection responsible for upper gastrointestinal symptoms (UGISs). Several causes of H. pylori infection include food ingestion and person-to-person transmission. Many lifestyle variables can affect the occurrence of UGISs such as coffee consumption and smoking.

Objective: To assess the association between smoking and coffee consumption and the occurrence of UGISs in patients with active H. pylori infection in Jazan city in Saudi Arabia.

Methodology: A descriptive cross-sectional research design was used to conduct the study between July 2022 and August 2022 in Jazan, southern Saudi Arabia. Male and female Saudis or …

Fungal Assisted Valorisation Of Polymeric Lignin: Mechanism, Enzymes And Perspectives, Kavya Dashora, Meghana Gattupalli, Gyan Datta Tripathi, Zoya Javed, Shweta Singh, Maria Tuohy, Prakash Kumar Sarangi, Deepti Diwan, Harikesh B. Singh, Vijai Kumar Gupta

2020-Current year OA Pubs

No abstract provided.

Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Z Ma, J Liu, B Li

School of Biomedical Sciences

Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cross-reactive universal vaccine antigen targets, capable of providing cross-protection against S. suis infection. Subunit vaccines based on the conserved proteins shared between different S. suis serotypes are potential candidates for such a universally protective vaccine. In the present study, phosphate ABC transporter ATP-binding protein PstB (PstB), an immunogenic protein of the S. suis bacterium, was expressed and purified, and then subjected to …

Evaluation Of Serum Concentration Of Acute-Phase Proteins (Haptoglobin And Serum Amyloid A) In The Affected Arabian Foals With Rhodococcosis, Ali Hassanpour, Sina Moghaddam

Faculty, Staff and Students Publications

BACKGROUND: Early detection of Rhodococcus equi pneumonia in foals is essential for horse health and for veterinarians.

OBJECTIVES: This study aimed to demonstrate the usefulness of assessing the serum concentration of acute-phase proteins (APPs) in the early diagnosis of pneumonia.

METHODS: The study evaluated APPs in 19 Arabian foals with R. equi pneumonia and compared them with 18 normal Arabian foals in equestrian clubs in Tabriz, Iran. Affected foals were identified through history, clinical findings and bacterial culture of tracheal washing. Biochemical methods and polymerase chain reaction tests were performed by examining the 16S rRNA and vapA genes to confirm …

Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, B Li

School of Biomedical Sciences

Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cross-reactive universal vaccine antigen targets, capable of providing cross-protection against S. suis infection. Subunit vaccines based on the conserved proteins shared between different S. suis serotypes are potential candidates for such a universally protective vaccine. In the present study, phosphate ABC transporter ATP-binding protein PstB (PstB), an immunogenic protein of the S. suis bacterium, was expressed and purified, and then subjected to …

Investigation Of The Effect Of Senescence On Daily Activity Patterns In Male Octopus Insularis, Mariam Steinblatt

Theses and Dissertations

Senescent male octopuses often show comparatively increased activity. We observed daily activity for an adult male Octopus insularis. The subject's diurnal behavior was marked movement or stationary to observe differences. Movement increased over 26 days, but the difference was non-significant. The observation period was likely short, and the subject already senescent.

The Impact Of Covid-19 On Pediatric Cardiac Arrest Outcomes: A Systematic Review And Meta-Analysis, Alla Navolokina, Jacek Smereka, Bernd W Böttiger, Michal Pruc, Raúl Juárez-Vela, Mansur Rahnama-Hezavah, Zubaid Rafique, Frank W Peacock, Kamil Safiejko, Lukasz Szarpak

Faculty, Staff and Students Publications

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic, required the donning of personal protective equipment during clinical contact, and continues to be a significant worldwide public health concern. Pediatric cardiac arrest is a rare but critical condition with a high mortality rate, the outcomes of which may be negatively affected by donning personal protective equipment. The aim of this study is to perform a systematic review and meta-analysis of the impact of the COVID-19 pandemic on pediatric cardiac arrest outcomes. We conducted a systematic review with meta-analysis in the following databases: PubMed, EMBASE, Scopus, Web of Science, …

Chronic And Postprandial Metabolic Responses To A Ketogenic Diet Compared To High-Carbohydrate And Habitual Diets In Trained Competitive Cyclists And Triathletes: A Randomized Crossover Trial, Austin J. Graybeal, Andreas Kreutzer, Kamiah Moss, Petra Rack, Garrett Augsburger, Robyn Braun-Trocchio, Jada L. Willis, Meena Shah

Faculty Publications

Extreme carbohydrate deficits during a ketogenic diet (KD) may result in metabolic adaptations reflective of low energy availability; however, the manifestation of these adaptations outside of exercise have yet to be elucidated in cyclists and triathletes. The purpose of this study is to investigate the chronic and postprandial metabolic responses to a KD compared to a high-carbohydrate diet (HCD) and habitual diet (HD) in trained competitive cyclists and triathletes. For this randomized crossover trial, six trained competitive cyclist and triathletes (F: 4, M: 2) followed an ad libitum KD and HCD for 14 d each after their HD. Fasting energy …

Discovery And Characterization Of A New Class Of O-Linking Oligosaccharyltransferases From The Moraxellaceae Family, Cory J Knoot, Paeton L Wantuch, Lloyd S Robinson, David A Rosen, Nichollas E Scott, Christian M Harding

2020-Current year OA Pubs

Bacterial protein glycosylation is commonly mediated by oligosaccharyltransferases (OTases) that transfer oligosaccharides en bloc from preassembled lipid-linked precursors to acceptor proteins. Natively, O-linking OTases usually transfer a single repeat unit of the O-antigen or capsular polysaccharide to the side chains of serine or threonine on acceptor proteins. Three major families of bacterial O-linking OTases have been described: PglL, PglS, and TfpO. TfpO is limited to transferring short oligosaccharides both in its native context and when heterologously expressed in glycoengineered Escherichia coli. On the other hand, PglL and PglS can transfer long-chain polysaccharides when expressed in glycoengineered E. coli. Herein, we …

The 2022 Monkeypox Epidemic And What Has Led To The Current State Of The Disease In The Us: A Systematic Review, Samriddh Chaudhari, Leah Treffeisen, Jaswinder Virk, Taral Parikh, Naveen Prasad Gopalakrishnan Ravikumar, Ashish M. Goti, Lokesh Goyal, Kanica Yashi

Student Publications

Monkeypox virus (MPOX) is a zoonotic disease in humans. It is similar genetically to its virus family member, smallpox. This virus has been studied since the 1970s. The virus remains endemic to the Congo and West African regions, but non-endemic spreads have been cited. The most recent non-endemic outbreak in the spring of 2022 amidst the current COVID-19 pandemic is of interest due to its impact on global medical, economic, and societal climates. This literature review aims to highlight the virology, clinical signs and symptoms, diagnosis, prevention, and treatment of MPOX and discuss the social implications of the recent 2022 …

Concentrations And Estimation Of The Annual Effective Doses Of Natural Radioactivity Uptake Through Ingestion Of Virgin And Extra Virgin Olive Oil, Eman Ahmed Albdady, Mahmoud El Ghazaly, Saad Abd El Aaal, Mostafa Abdelrahman, Nasef Mansour, Mona Elsayed Frarrag

International Journal of Thin Film Science and Technology

This study assesses the natural radioactive concentrations in virgin olive oil in Egypt. The presence and concentrations of naturally occurring radioactive materials (NORM) in 26 olive oil samples collected from different locations in Saini were conducted using two techniques: gamma spectroscopy using a high purity germanium detector (HPGe) and inductively coupled plasma-mass spectroscopy (ICP-MS). Because of their very low concentrations, the radioactivity of NORM was below the detection limits of the HPGe detector for the time of measurement, On the other hand ICP-MS results showed the concentrations of natural radioactive elements such as uranium and thorium in some examined samples. …

Markets, Businesses, And Consumption In Refugees Settlements: A Review And Future Research Trajectory, Stefanie Beninger

Markets, Globalization & Development Review

The global refugee crisis is increasing, and many refugees will end up living in refugee settlements, also known as refugee camps. These settlements have dynamic economic activities, and such activities deserve attention. This paper draws upon academic and practitioner work to describe pertinent aspects of consumption, businesses, and markets in these settlements, including in relation to multiple stakeholders. These stakeholders can include, for example, governments, aid agencies, private sector, and local community groups. Based on these insights, the paper identifies key theoretical areas in need of attention related to these economic activities in refugee settlements, including market change, resilience, and …

Full Issue: Fall 2017

DePaul Magazine

In this issue of DePaul Magazine meet alumni employed by the Chicago Cubs and the White Sox, alumni firemen who share what it’s like to battle a blaze, learn about DePaul’s study abroad program, and discover the compelling World War I story of a DePaul legacy family.

Rethinking Food Regime As Gender Regime: Agrarian Change And The Politics Of Social Reproduction, Diana Mincyte

Publications and Research

This paper presents a synthetic reading of the food regime and gender regime concepts to consider current trends in deagrarianization. Its underlying goal is to articulate a research agenda for studying the food regime through the lens of gender and labor relations. Combining insights from feminist scholarship and early debates on family farming in agrarian studies, it underscores the role of social reproduction in shaping agro-food systems. Focusing on relations in production it reconsiders family, kinship and strong ties as a form of social organization in capitalist production, emphasizes the significance of ideology on the household level, and underscores the …

Echinococcus Multilocularis Calreticulin Interferes With C1q-Mediated Complement Activation, Siqi Xian, Lujuan Chen, Yan Yan, Jianfang Chen, Guixia Yu, Yuxiao Shao, Bin Zhan, Yanhai Wang, Limei Zhao

Faculty, Staff and Students Publications

As a zoonotic disease caused by Echinococcus multilocularis larvae, alveolar echinococcosis (AE) is one of the most severe forms of parasitic infection. Over a long evolutional process E. multilocularis has developed complex strategies to escape host immune attack and survive within a host. However, the mechanisms underlying immune evasion remain unclear. Here we investigated the binding activity of E. multilocularis calreticulin (EmCRT), a highly conserved Ca2+-binding protein, to human complement C1q and its ability to inhibit classical complement activation. ELISA, Far Western blotting and immunoprecipitation results demonstrated that both recombinant and natural EmCRTs bound to human C1q, …