Digital Commons Network^™

Property And Sovereignty In America: A History Of Title Registries & Jurisdictional Power, K-Sue Park

Georgetown Law Faculty Publications and Other Works

This Article tells an untold history of the American title registry—a colonial bureaucratic innovation that, though overlooked and understudied, constitutes one of the most fundamental elements of the U.S. property system today. Prior scholars have focused exclusively on its role in catalyzing property markets, while mostly ignoring their main sources in the colonies -- expropriated lands and enslaved people. This analysis centers the institution’s work of organizing and “proving” claims that were not only individual but collective, to affirm encroachments on tribal nations’ lands and scaffold colonies’ tenuous but growing political, jurisdictional power. In other words, American property and property …

Glua3 Subunits Are Required For Appropriate Assembly Of Ampar Glua2 And Glua4 Subunits On Cochlear Afferent Synapses And For Presynaptic Ribbon Modiolar-Pillar Morphology, Mark A Rutherford, Atri Bhattacharyya, Maolei Xiao, Hou-Ming Cai, Indra Pal, Maria Eulalia Rubio

2020-Current year OA Pubs

Cochlear sound encoding depends on α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), but reliance on specific pore-forming subunits is unknown. With 5-week-old male C57BL/6J

Prm-Reactive Antibodies Reveal A Role For Partially Mature Virions In Dengue Virus Pathogenesis, Kimberly A Dowd, Laura A Vanblargan, Rita E Chen, Bradley M Whitener, Jennifer Govero, Soila Sukupolvi-Petty, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Cleavage of the flavivirus premembrane (prM) structural protein during maturation can be inefficient. The contribution of partially mature flavivirus virions that retain uncleaved prM to pathogenesis during primary infection is unknown. To investigate this question, we characterized the functional properties of newly-generated dengue virus (DENV) prM-reactive monoclonal antibodies (mAbs) in vitro and using a mouse model of DENV disease. Anti-prM mAbs neutralized DENV infection in a virion maturation state-dependent manner. Alanine scanning mutagenesis and cryoelectron microscopy of anti-prM mAbs in complex with immature DENV defined two modes of attachment to a single antigenic site. In vivo, passive transfer of intact …

Characterizing Pediatric Unilateral Brain Damage: Unilateral Spatial Neglect, Balance, And More, Emerson Hart

MUSC Theses and Dissertations

Pediatric unilateral brain damage is a costly, impactful condition. There are many subsequent impairments that children experience after pediatric unilateral brain damage, two of which are unilateral spatial neglect (USN) and balance impairments. This project aims to compile the existing literature regarding USN in children, analyze insurance billing data to characterize the population, and evaluate balance and USN in a small case-control cohort of children with and without unilateral brain damage. The literature search elucidated the scant literature available addressing USN, including a lack of quality assessments to definitively identify USN. Insurance billing analyses showed an incredibly heterogeneous group, very …

Antibody-Dependent Enhancement Activity Of A Plant-Made Vaccine Against West Nile Virus, Amber M. Paul, Haiyan Sun, Dhiraj Acharya, Huafang Lai, Junyun He, Fengwei Bai, Qiang Chen

Publications

West Nile virus (WNV) causes annual outbreaks globally and is the leading cause of mosquito-borne disease in Unite States. In the absence of licensed therapeutics, there is an urgent need to develop effective and safe human vaccines against WNV. One of the major safety concerns for WNV vaccine development is the risk of increasing infection by related flaviviruses in vaccinated subjects via antibody-dependent enhancement of infection (ADE). Herein, we report the development of a plant-based vaccine candidate that provides protective immunity against a lethal WNV challenge mice, while minimizes the risk of ADE for infection by Zika (ZIKV) and dengue …

Strategies For The Improvement Of Healthcare Through Simulation, Roger C. Lankheet

Dissertations

Medical errors continue to plague the healthcare industry. The annual rates of morbidity are approximately 2.69 million (AHRQ, 2019), while mortality rates exceed 400,000 per annum (Makary & Daniel, 2016). There may be no panacea to combat these egregious rates. However, simulation of patient care events may better prepare healthcare professionals to prevent medical errors as it has been proven to be an effective learning strategy (Kirkham, 2018), enhancing skills while gaining experiential knowledge, without risk to actual patients.

The purpose of this qualitative study was to gain a better understanding of factors that impede or foster the frequent utilization …

Harnessing The Therapeutic Vulnerability Of Mmr Heterogeneity In Colorectal Cancer, Gayathri Anandappa, Michael J Overman

Faculty, Staff and Student Publications

In a recent issue of Cancer Cell, Amodio and colleagues report an interesting method of modulating immunosurveillance in colorectal tumors with DNA mismatch repair (MMR) heterogeneity.1 By pharmacologically enriching the MMR deficient (MMRd) component using 6-thioguanine, they demonstrate improved tumor control in murine models.

Biorisk Management, Laboratory Acquired Infections And Clinical Containment, Kashif Ali, Furqan Kabir, Esmeralda Meyer

Department of Paediatrics and Child Health

No abstract provided.

Climate Change, Human Health, And Resilience In The Holocene, Gwen Robbins Schug, Jane E. Buikstra, Sharon N. Dewitte, Brenda J. Baker, Elizabeth Berger, Michele R. Buzon, Anna M. Davies-Barrett, Lynne Goldstein, Anne L. Grauer, Lesley A. Gregoricka, Siân E. Halcrow, Kelly J. Knudson, Clark Spencer Larsen, Debra L. Martin, Kenneth C. Nystrom, Megan A. Perry, Charlotte A. Roberts, Ana Luisa Santos, Christopher M. Stojanowski, Jorge A. Suby, Daniel H. Temple, Tiffany A. Tung, Melandri Vlok, Tatyana Watson-Glen, Sonia R. Zakrzewski

Anthropology: Faculty Publications and Other Works

Climate change is an indisputable threat to human health, especially for societies already confronted with rising social inequality, political and economic uncertainty, and a cascade of concurrent environmental challenges. Archaeological data about past climate and environment provide an important source of evidence about the potential challenges humans face and the long-term outcomes of alternative short-term adaptive strategies. Evidence from well-dated archaeological human skeletons and mummified remains speaks directly to patterns of human health over time through changing circumstances. Here, we describe variation in human epidemiological patterns in the context of past rapid climate change (RCC) events and other periods of …

Entry Receptors - The Gateway To Alphavirus Infection, Ofer Zimmerman, Autumn C. Holmes, Natasha M. Kafai, Lucas J. Adams, Michael S. Diamond

2020-Current year OA Pubs

Alphaviruses are enveloped, insect-transmitted, positive-sense RNA viruses that infect humans and other animals and cause a range of clinical manifestations, including arthritis, musculoskeletal disease, meningitis, encephalitis, and death. Over the past four years, aided by CRISPR/Cas9-based genetic screening approaches, intensive research efforts have focused on identifying entry receptors for alphaviruses to better understand the basis for cellular and species tropism. Herein, we review approaches to alphavirus receptor identification and how these were used for discovery. The identification of new receptors advances our understanding of viral pathogenesis, tropism, and evolution and is expected to contribute to the development of novel strategies …

Media And Disaster Mitigation Literacy, Yuanita Setyastuti, Lalita Hanief, Aulia Shafira Putri

Library Philosophy and Practice (e-journal)

This study aims to examine the effectiveness of disaster communication media in improving disaster mitigation literacy for the community in Pengaron District, Banjar Regency. This study is a quantitative research and uses an experimental type. Data collection techniques used pre-test and post-test questionnaires, observation and documentation. Respondents in this study were people who were affected by floods in January 2022 in Pengaron, Banjar Regency. Supporting informants are BNPB as an institution involved in flood disaster management.

The sample in this study amounted to 20 people for the experimental group and 20 people for the control group with data analysis techniques …

The Prospector, January 17, 2023, Utep Student Publications

The Prospector

Headline: Behind the Faces at the Border

The Prospector, January 17, 2023, Utep Student Publications

The Prospector

Headline: Behind the Faces at the Border

Differential Effects Of Anti-Cd20 Therapy On Cd4 And Cd8 T Cells And Implication Of Cd20-Expressing Cd8 T Cells In Ms Disease Activity, Koji Shinoda, Anne H Cross, Et Al.

2020-Current year OA Pubs

A small proportion of multiple sclerosis (MS) patients develop new disease activity soon after starting anti-CD20 therapy. This activity does not recur with further dosing, possibly reflecting deeper depletion of CD20-expressing cells with repeat infusions. We assessed cellular immune profiles and their association with transient disease activity following anti-CD20 initiation as a window into relapsing disease biology. Peripheral blood mononuclear cells from independent discovery and validation cohorts of MS patients initiating ocrelizumab were assessed for phenotypic and functional profiles using multiparametric flow cytometry. Pretreatment CD20-expressing T cells, especially CD20

Insights From Fossil-Bound Nitrogen Isotopes In Diatoms, Foraminifera, And Corals, Rebecca S. Robinson, Sandi M. Smart, Jonathan D. Cybulski, Kelton W. Mcmahon, Basia Marcks, Catherine Nowakowski

Graduate School of Oceanography Faculty Publications

Nitrogen is a major limiting element for biological productivity, and thus understanding past variations in nitrogen cycling is central to understanding past and future ocean biogeochemical cycling, global climate cycles, and biodiversity. Organic nitrogen encapsulated in fossil biominerals is generally protected from alteration, making it an important archive of the marine nitrogen cycle on seasonal to million-year timescales. The isotopic composition of fossil-bound nitrogen reflects variations in the large-scale nitrogen inventory, local sources and processing, and ecological and physiological traits of organisms. The ability to measure trace amounts of fossil-bound nitrogen has expanded with recent method developments. In this article, …

Dubbing Or Subtitling English Animated Films Into Arabic The Case Of The Adventure Animated Film "How To Train Your Dragon: The Hidden World", Maya El Abed, Mary Yazbeck

Al-Kīmiyā

This study investigates certain stylistic, linguistic, technical and cultural constraints that translators usually encounter in the subtitling and dubbing of English films into the Arabic language. It highlights the solutions that they used in tackling these constraints by comparing the subtitled and dubbed version of the third instalment of the popular English adventure animated film How to Train Your Dragon: The Hidden World. In light of the basic technical constraints and the specific stylistic, linguistic and cultural constraints rooted in translation for audiences whose mother-tongue is Arabic, it is suggested that particular elements of translation theory can be beneficial …

Transformation Numérique Et Enseignement De La Traduction : Une Rétrospective Pour Mieux Envisager L’Avenir, Lina Sader Feghali, Wadad Wazen Gergy

Al-Kīmiyā

This article outlines the stages of digital transformation undertaken at the School of Translators and Interpreters of Beirut (École de traducteurs et d’interprètes de Beyrouth) before and after the COVID-19 pandemic in order to evaluate the changes that encouraged instructors to rethink the complex links between technology and translation teaching. This complex transformation would not have occurred without actions taken at the institutional level and the sense of urgency felt by all stakeholders in response to lockdown measures. By evaluating the strategy followed to see how successful it has been in creating the conditions for the acceptability of technology and …

Introduction, La Rédaction De « Al-Kīmiyā »

Al-Kīmiyā

S’il est vrai que le numéro 21 de notre revue Al-Kīmiyā a pris davantage de temps à dévoiler ses articles au grand public, il est aussi tout à fait vrai que la naissance de ce numéro s’inscrit en quelque sorte dans un effort de survie, pour ne pas employer le mot de résilience devenu répugnant pour beaucoup de Libanais fatigués d’inventer de l’espoir dans un pays qui ne cesse de se défigurer sous leurs yeux [...]

Exploring Therapeutic Strategies For Infantile Neuronal Axonal Dystrophy (Inad/Park14), Guang Lin, Burak Tepe, Geoff Mcgrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes J H Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen

Faculty, Staff and Students Publications

Infantile neuroaxonal dystrophy (INAD) is caused by recessive variants in PLA2G6 and is a lethal pediatric neurodegenerative disorder. Loss of the Drosophila homolog of PLA2G6, leads to ceramide accumulation, lysosome expansion, and mitochondrial defects. Here, we report that retromer function, ceramide metabolism, the endolysosomal pathway, and mitochondrial morphology are affected in INAD patient-derived neurons. We show that in INAD mouse models, the same features are affected in Purkinje cells, arguing that the neuropathological mechanisms are evolutionary conserved and that these features can be used as biomarkers. We tested 20 drugs that target these pathways and found that Ambroxol, Desipramine, …

The Legislative Graveyard: A Review Of Virginia's 2022 Regular General Assembly Session, Kaylin Cecchini, Haley Edmonds

Richmond Public Interest Law Review

In 2019, Democrats won a majority in the House of Delegates and the Senate, and the Commonwealth was led by a Democratic Governor. The Democrats’ majority trifecta, which they had obtained for the first time since 1992, was once again lost on November 2, 2021, when Virginians voted to renew the Republican leadership in the Office of the Governor and in the House of Delegates. Under this once again bifurcated, yet unusually polarized, assembly, legislators on either side of the political aisle faced an uphill battle getting legislation passed, with the majority of bills ending in a stalemate. As a …

Genetic And Ecological Drivers Of Molt In A Migratory Bird, Andrea Contina, Christen M. Bossu, Daniel Allen, Michael B. Wunder, Kristen Ruegg

School of Integrative Biological & Chemical Sciences Faculty Publications

The ability of animals to sync the timing and location of molting (the replacement of hair, skin, exoskeletons or feathers) with peaks in resource availability has important implications for their ecology and evolution. In migratory birds, the timing and location of pre-migratory feather molting, a period when feathers are shed and replaced with newer, more aerodynamic feathers, can vary within and between species. While hypotheses to explain the evolution of intraspecific variation in the timing and location of molt have been proposed, little is known about the genetic basis of this trait or the specific environmental drivers that may result …

Bob Beaugrand, Oral History Interview, 2022, Matt Jones

Oral Histories

Bob Beaugrand, brother of fellow Arm of Honor, Michael Beaugrand, wa an active member of the Arm of Honor Fraternity from 1986 until 1990. Beaugrand details his upbringing in the Ypsilanti area and the origins of the moniker "YpsiTucky." Grandson of the first female foreman at the Ford Motor Company, Ramona Bullet, Bob Beaugrand found the Arm of Honor following serving in the US Armed Forces and deciding that the military was not the future he wanted. Beaugrand describes his closer friends in the fraternity, the philanthropic nature of Arm parties, rivalries with Theta Chi and other fraternities, and the …

E-Learning Participation Among Senior Secondary Students During Covid19 Pandemic Lockdown In Epe Local Government Area Of Lagos State, Adesanya Olusegun Oyeleye, Oshodi Odunola O Dr

Library Philosophy and Practice (e-journal)

The study investigated e-learning participation among senior secondary school students during COVID-19 in Epe local government area of Lagos State. This is to ascertain the level of students’ participation in using e-learning platforms in Epe local government area of Lagos State. The descriptive research design was adopted, while a multi-stage sampling procedure was used, stratified sampling technique was used to select senior secondary school in Epe local government area. While simple random sampling method was employed to select 195 students (116 males and 79 females) participant in the study. A structured questionnaire tagged “tagged Questionnaire on Senior Secondary Students …

Lecturers’ Perception And Participation On E-Learning Platform In Michael Otedola College Of Primary Education During Covid-19 Pandemic Lockdown, Adesanya Olusegun Oyeleye, Famuiwa Folasade O

Library Philosophy and Practice (e-journal)

The study investigated lecturers’ perception and participation on e-learning platform in Michael Otedola College of Primary Education in Lagos State during COVID-19 pandemic lockdown. This is to ascertain the level of lecturers’ perception and participation on the use of the college e-learning platforms. The descriptive research design was adopted, while total enumeration was used to select respondents for the study. A structured questionnaire tagged “Lecturers’ Perception and Participation in E-learning learning platform in Michael Otedola College of Primary Education during COVID-19 Pandemic Lockdown (LPPMOCPEC19PL) with the reliability coefficient of 0.87 was used for data collected. Four research questions were …

A 10-Year Collection Of Roadkilled Avifauna In A Stretch Of The Br-040 Highway In Southeastern Brazil, Cecília Bueno, Guilherme Renzo Rocha Brito, Daniel Honorato Firme, Daniel Monteiro Figueira, Mariana Silva Ferreira

Neotropical Biodiversity

No abstract provided.

Embracing Ecology And Fantasy: A Review Of The Wonders Of Creation, Carl P. Fictorie

Faculty Work Comprehensive List

"[Page] particularly promotes following the practice of 'slow' reading of nature, to stop and pay attention to the place and take in even the smallest details."

Posting about ­­­­­­­­the book The Wonders of Creation from In All Things - an online journal for critical reflection on faith, culture, art, and every ordinary-yet-graced square inch of God’s creation.

https://inallthings.org/embracing-ecology-and-fantasy-a-review-of-the-wonders-of-creation/

Planarians To Schistosomes: An Overview Of Flatworm Cell-Types And Regulators, J Lee

Faculty, Staff and Student Publications

Schistosomiasis remains a major neglected tropical disease that afflicts over 200 million people globally. Schistosomes, the aetiological agent of schistosomiasis, are parasitic flatworms that propagate between molluscan and mammalian hosts. Inside the mammalian host, schistosomes rapidly grow over 100-fold in size and develop into a sexually mature male or female that thrives in the bloodstream for several decades. Recent work has identified schistosome stem cells as the source that drives parasite transmission, reproduction and longevity. Moreover, studies have begun to uncover molecular programmes deployed by stem cells that are essential for tissue development and maintenance, parasite survival and immune evasion. …

Toward Culturally And Linguistically Responsive E-Learning In Post-Covid-19 Higher Education: Perspectives From The United Arab Emirates, Sarah Hopkyns

All Works

The COVID-19 pandemic has caused dramatic shifts in education worldwide. In the spring of 2020, universities abruptly moved to emergency remote teaching and learning (ERT&L), with online and hybrid education continuing into the post-pandemic era. In the Gulf, cultural, religious, and sociolinguistic dynamics can present additional challenges for teaching and learning online. Reluctance to use cameras due to modesty, privacy, and E-safety concerns, amongst others, affects interaction and rapport. This article presents empirical data from a qualitative phenomenological case study investigating male and female Emirati university students’ (n = 107) perspectives on access, interaction, and engagement during Zoom classes in …

‘Can You See What I See?’: An Art Project Promoting Living Well With Dementia, Jennifer K. Fortuna

The Open Journal of Occupational Therapy

Caroline Hyland, an illustrator and former occupational therapist based in Dublin, Ireland, provided the cover art for the Winter 2023 edition of The Open Journal of Occupational Therapy (OJOT). “Can You See What I See?” is an acrylic painting on black textured paper. The piece was inspired by Caroline’s grandmother Kathleen Duhig, her love of flowers, and the song “The Dutchman.” Kathleen and three of her sisters lived with dementia. This painting, and several others, are featured in a book Caroline wrote to support living well with dementia. By combining her artistic talents and training as an occupational therapist, Caroline …

Job Demands Of Occupational Therapy Clinical Placements: A Descriptive Study Using The Practicum Demands Measure©, Behdin Nowrouzi-Kia, Donna Barker, Jill Stier, Joyce Lo

The Open Journal of Occupational Therapy

The purpose of this study was to group and analyze the Practicum Demands Measure^© (PDM) data collected over 2 academic years and create a general profile of demands across practicum settings. The data will be used to guide faculty in the most suitable placement of students requiring accommodations for a disability. The study used a secondary analysis design to analyze the 538 participant PDM data collected over the 2017/2018 and 2018/2019 academic years. Most of the sampled students were in fieldwork Level I and worked in mental health settings. The students reported physical demands, such as lifting more …