Digital Commons Network^™

Association Of Omega 3 Polyunsaturated Fatty Acids With Incident Chronic Kidney Disease: Pooled Analysis Of 19 Cohorts, Kwok Leung Ong, Matti Marklund, Liping Huang, Kerry-Anne Rye, Nicholas Hui, Xiong-Fei Pan, Casey M Rebholz, Hyunju Kim, Lyn M Steffen, Anniek C Van Westing, Johanna M Geleijnse, Ellen K Hoogeveen, Yun-Yu Chen, Kuo-Liong Chien, Amanda M Fretts, Rozenn N Lemaitre, Fumiaki Imamura, Nita G Forouhi, Nicholas J Wareham, Anna Birukov, Susanne Jäger, Olga Kuxhaus, Matthias B Schulze, Vanessa Derenji De Mello, Jaakko Tuomilehto, Matti Uusitupa, Jaana Lindström, Nathan Tintle, William S Harris, Keisuke Yamasaki, Yoichiro Hirakawa, Toshiharu Ninomiya, Toshiko Tanaka, Luigi Ferrucci, Stefania Bandinelli, Jyrki K Virtanen, Ari Voutilainen, Tharusha Jayasena, Anbupalam Thalamuthu, Anne Poljak, Sonia Bustamante, Perminder S Sachdev, Mackenzie K Senn, Stephen S Rich, Michael Y Tsai, Alexis C Wood, Markku Laakso, Maria Lankinen, Xiaowei Yang, Liang Sun, Huaixing Li, Xu Lin, Christoph Nowak, Johan Ärnlöv, Ulf Risérus, Lars Lind, Mélanie Le Goff, Cécilia Samieri, Catherine Helmer, Frank Qian, Renata Micha, Adrienne Tin, Anna Köttgen, Ian H De Boer, David S Siscovick, Dariush Mozaffarian, Jason Hy Wu

Faculty, Staff and Students Publications

OBJECTIVE: To assess the prospective associations of circulating levels of omega 3 polyunsaturated fatty acid (n-3 PUFA) biomarkers (including plant derived α linolenic acid and seafood derived eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid) with incident chronic kidney disease (CKD).

DESIGN: Pooled analysis.

DATA SOURCES: A consortium of 19 studies from 12 countries identified up to May 2020.

STUDY SELECTION: Prospective studies with measured n-3 PUFA biomarker data and incident CKD based on estimated glomerular filtration rate.

DATA EXTRACTION AND SYNTHESIS: Each participating cohort conducted de novo analysis with prespecified and consistent exposures, outcomes, covariates, and models. The results were …

Expanding Potential Dental Applications Of Glass Ionomer Cement By Incorporating With Nano-Hydroxyapatite, Kifayah K. Thbayh, Rafid M. Albadr, Kareema M. Ziadan, Béla Fiser

Karbala International Journal of Modern Science

Glass ionomer cement (GIC) is a common restorative material in dentistry, but it exhibits relatively weak mechanical properties. The present study focuses on incorporating nano-hydroxyapatite (nHAP) with different ratios (1, 3, 5, and 7wt%) in GIC to improve its properties. Mechanical properties, sorption, solubility, and diffusion coefficients after storage in distilled water for 60 days were studied. The highest sorption was measured at 7%wt (46.66 µg/mm3), and the lowest solubility was in the case of the sample containing 5% (29.166 µg/mm3). Moreover, the highest value of diffu-sion coefficient was 8.5 mm/s in the case of the sample with 7%wt nHAP. …

Illuminating Chinese Aesthetics With Kant’S Account Of Genius? Possibility And Difficulty, Kefu Zhu

Comparative Philosophy

Many scholars interpret Chinese Aesthetics with the Kantian theory of genius because they seem to form a parallel: similar innate and spontaneous mental talents that exceed normal cognition and imagination generates beautiful arts with similar extraordinary qualities. I argue that projecting Kant’s genius to illuminate the creative power analogically, i.e., the carefree-wandering mind, is infeasible. The theory of genius assumes a critical project that stipulates a valuable way to exercise the power of judgment. Genius is only a postulated idea for successfully making aesthetic judgments on artworks. In contrast, the carefree-wandering mind assumes a Daoist metaphysical-ethical theory centering on the …

How Al-Farabi’S Interpretative Method Can Engage With Aristotle’S Method In Cognition And Practical Philosophy, Meysam Shirvani

Comparative Philosophy

Following Aristotle, al-Farabi divides philosophy into theoretical and practical each of which requires some specific methodology both in interpretation and cognition. Based on this division, there may arguably be four methodologies for four parts: 1) cognition of theoretical philosophy 2) interpretation of practical philosophy 3) cognition of practical philosophy 4) interpretation of practical philosophy. This paper focuses on the last one: the methodology of interpreting practical philosophy. Al-Farabi has an undeniably significant contribution to practical philosophy as a commentator on Greek philosophy and as a founder. In this paper, I investigate how al-Farabi (870-950 AD) read classical practical philosophy to …

Full Issue: Volume 1, Issue 1, Editorial Board

Crossings: Swarthmore Undergraduate Feminist Research Journal

No abstract provided.

Sex In The Bible: A Poetic Female Retelling, Gabriella Raffetto

Crossings: Swarthmore Undergraduate Feminist Research Journal

In my poetic analysis, I tease out the differences between Biblical and modern conceptions of rape. Many of my ‘episodes’ feature rape narratives between a husband and wife or concubine/slave; in the Biblical narrative, these relations were not considered rape, because rape only constituted relationships outside of legal bounds. In this way, I attempt to diversify preexisting stories in the Biblical narrative, making monsters out of praised patriarchs; even God is not safe from becoming the villain. In this way, I paint the patriarchal system in the Bible as a gothic house disguised in tradition and spirituality that women must …

Àṣẹ After Man: The Rupture Of The Christian-Colonial Project As Decolonial Ceremony, Eden Segbefia

Crossings: Swarthmore Undergraduate Feminist Research Journal

This project is a theoretical exploration of the Yoruba concept of àṣẹ and its role in unsettling the hierarchies imposed by Christian colonialism. Sylvia Wynter's explanation of the ways in which Christian colonialism has affected the very concept of Man proves crucial here. Àṣẹ is an example of a decolonial concept because of its ability to rearrange animacy, especially as it is conceived in Western European epistemology. Wynter and other interlocutors are utilized to support this argument and imagine new possibilities in considering the relationships between Christian colonialism, alterity, plasticity, and animacy.

Masculinized Sovereignty: Understanding Violence Towards Mice And The Nonhuman, Anisha Prakash

Crossings: Swarthmore Undergraduate Feminist Research Journal

This paper attempts to analyze how the definition of the normative “human” categorizes bodies that represent alternative political order against settler colonialism, and how the subjects that go against the dominant ideal of human are prohibited from living a free life, if not altogether eliminated. While conducting research, I view the lab as a site of social advancement where the differences between humans and nonhumans create a community of shared purpose. An interrogation of the laboratory as a site of violence can help us better understand how the State’s capitalist modes of advancement and production harm those of indigenous people, …

Sitting Here With You In The Future: Reimagining The Human Through Digital Art, Jared Z. Sloan

Crossings: Swarthmore Undergraduate Feminist Research Journal

This paper presents a novel construction of the Human that arises from digital art. Taking an interdisciplinary approach incorporating perspectives from queer theory, afropessimism, science and technology studies, and more, I analyze the works of three digital artists: Lucas LaRochelle, Arafa Hamadi, and Natalie Paneng. I chart the ways in which these artists negotiate borders between the physical and digital, human and non-human, and real and fantastical to challenge hegemonic Western ideas about humanity and the individual. I claim that by restricting the information available to the user in various ways, the picture of the Human that emerges from each …

“The Work We Came Here To Do”: Crossings, An Introduction, José E. Valdivia Heredia , '23

Crossings: Swarthmore Undergraduate Feminist Research Journal

No abstract provided.

Faculty Senate Minutes 2023-01-17, The University Of Texas Rio Grande Valley. Faculty Senate.

Faculty Senate Minutes

No abstract provided.

Faculty Senate Agenda 2023-01-17, The University Of Texas Rio Grande Valley. Faculty Senate.

Faculty Senate Agendas

No abstract provided.

Ud Student-Athlete Splits Summer Between Soccer And Microbiology Research, Lucy Waskiewicz

College of Arts and Sciences Newsroom

UD women's soccer player Jessica Sheldon spent summer 2022 achieving goals in the science lab.

Romosozumab, Kristina Krupa, Mayur Parmar, Linda F. Delo

HPD Articles

No abstract provided.

Abaloparatide, Miis Akel, Mayur Parmar

HPD Articles

No abstract provided.

2023-January-17-Animation School Rankings, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (Jan. 17, 2023) — East Tennessee State University has been ranked the top animation school in Tennessee and No. 7 nationally among schools offering an animation-related B.S. degree in the 2023 Animation School Rankings.

The online resource Animation Career Review considered nearly 200 schools with animation programs across the United States in determining the 12^th annual rankings.

The ETSU Digital Media Department in the College of Business and Technology offers a Bachelor of Science in digital media with concentrations in animation, game design, visualization and visual effects. There is also a digital media minor for students …

Gravity Wave Drag Parameterizations For Earth’S Atmosphere, Christopher J. Heale, Christopher G. Kruse, Jadwiga H. Richter, M. Joan Alexander, Julio T. Bacmeister, Junhong Wei

Publications

Atmospheric gravity waves (GWs), or buoyancy waves, transport momentum and energy through Earth’s atmosphere. GWs are important at nearly all levels of the atmosphere, though, the momentum they transport is particularly important in general circulation of the middle and upper atmosphere. Primary sources of atmospheric GWs are flow over mountains, moist convection, and imbalances in jet/frontal systems. Secondary GWs can also be generated as a result of dissipation of a primary GWs. Gravity waves typically have horizontal wavelengths of 10’s to 100’s of kilometers, though, they can have scales of 1’s to 1000’s of kilometers as well. Current effective resolutions …

Professor Franklin’S Annotated Bibliography Of Young Adult Literature, 2021—22, John Franklin

Open Educational Resources - English and Modern Languages

Designed to be a useful, time-saving source of primary reading material, Professor Franklin’s Annotated Bibliography of Young Adult Literature, 2021—22 includes his notes and reading recommendations for 195 authors, editors and illustrators; 205 titles; and 67,454 pages of reading.

The Effects Of Salinity And Acetaminophen On The Aquatic Snail Physa Acuta, Michelle Sackey-Ansah, Megan Mackey, Daniel Elias, Jason Doll, Alyssa Brookhart

Journal of the South Carolina Academy of Science

Pharmaceuticals are increasingly detected in water bodies, and their presence can negatively impact aquatic organisms. This effect can be amplified when combined with increasing salinity in freshwater ecosystems. Acetaminophen is a widely used analgesic that is commonly found in river, streams, and waters where it is discharged directly. Therefore, organisms present in these locations (e.g., insects, snails, amphibians, and fish) are likely to be affected by acetaminophen. In this study, we determined the effects of elevated salinity (0.68 g/L), acetaminophen (500 µg/L) and combined elevated salinity (0.68 g/L) and acetaminophen (500 µg/L), on the growth, reproduction, and movement of the …

Antibody-Dependent Enhancement Activity Of A Plant-Made Vaccine Against West Nile Virus, Haiyan Sun, Dhiraj Acharya, Amber M. Paul, Huafang Lai, Junyun He, Fengwei Bai, Qiang Chen

Faculty Publications

West Nile virus (WNV) causes annual outbreaks globally and is the leading cause of mosquito-borne disease in Unite States. In the absence of licensed therapeutics, there is an urgent need to develop effective and safe human vaccines against WNV. One of the major safety concerns for WNV vaccine development is the risk of increasing infection by related flaviviruses in vaccinated subjects via antibody-dependent enhancement of infection (ADE). Herein, we report the development of a plant-based vaccine candidate that provides protective immunity against a lethal WNV challenge mice, while minimizes the risk of ADE for infection by Zika (ZIKV) and dengue …

Metamobility: Connecting Future Mobility With Metaverse, Haoxin Wang, Ziran Wang, Dawei Chen, Qiang Liu, Hongyu Ke, Kyungtae Han

School of Computing: Faculty Publications

A Metaverse is a perpetual, immersive, and shared digital universe that is linked to but beyond the physical reality, and this emerging technology is attracting enormous attention from different industries. In this article, we define the first holistic realization of the metaverse in the mobility domain, coined as “metamobility”. We present our vision of what metamobility will be and describe its basic architecture. We also propose two use cases, tactile live maps and meta-empowered advanced driver-assistance systems (ADAS), to demonstrate how the metamobility will benefit and reshape future mobility systems. Each use case is discussed from the perspective of the …

Property And Sovereignty In America: A History Of Title Registries & Jurisdictional Power, K-Sue Park

Georgetown Law Faculty Publications and Other Works

This Article tells an untold history of the American title registry—a colonial bureaucratic innovation that, though overlooked and understudied, constitutes one of the most fundamental elements of the U.S. property system today. Prior scholars have focused exclusively on its role in catalyzing property markets, while mostly ignoring their main sources in the colonies -- expropriated lands and enslaved people. This analysis centers the institution’s work of organizing and “proving” claims that were not only individual but collective, to affirm encroachments on tribal nations’ lands and scaffold colonies’ tenuous but growing political, jurisdictional power. In other words, American property and property …

Glua3 Subunits Are Required For Appropriate Assembly Of Ampar Glua2 And Glua4 Subunits On Cochlear Afferent Synapses And For Presynaptic Ribbon Modiolar-Pillar Morphology, Mark A Rutherford, Atri Bhattacharyya, Maolei Xiao, Hou-Ming Cai, Indra Pal, Maria Eulalia Rubio

2020-Current year OA Pubs

Cochlear sound encoding depends on α-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors (AMPARs), but reliance on specific pore-forming subunits is unknown. With 5-week-old male C57BL/6J

Prm-Reactive Antibodies Reveal A Role For Partially Mature Virions In Dengue Virus Pathogenesis, Kimberly A Dowd, Laura A Vanblargan, Rita E Chen, Bradley M Whitener, Jennifer Govero, Soila Sukupolvi-Petty, Michael S Diamond, Et Al.

2020-Current year OA Pubs

Cleavage of the flavivirus premembrane (prM) structural protein during maturation can be inefficient. The contribution of partially mature flavivirus virions that retain uncleaved prM to pathogenesis during primary infection is unknown. To investigate this question, we characterized the functional properties of newly-generated dengue virus (DENV) prM-reactive monoclonal antibodies (mAbs) in vitro and using a mouse model of DENV disease. Anti-prM mAbs neutralized DENV infection in a virion maturation state-dependent manner. Alanine scanning mutagenesis and cryoelectron microscopy of anti-prM mAbs in complex with immature DENV defined two modes of attachment to a single antigenic site. In vivo, passive transfer of intact …

Characterizing Pediatric Unilateral Brain Damage: Unilateral Spatial Neglect, Balance, And More, Emerson Hart

MUSC Theses and Dissertations

Pediatric unilateral brain damage is a costly, impactful condition. There are many subsequent impairments that children experience after pediatric unilateral brain damage, two of which are unilateral spatial neglect (USN) and balance impairments. This project aims to compile the existing literature regarding USN in children, analyze insurance billing data to characterize the population, and evaluate balance and USN in a small case-control cohort of children with and without unilateral brain damage. The literature search elucidated the scant literature available addressing USN, including a lack of quality assessments to definitively identify USN. Insurance billing analyses showed an incredibly heterogeneous group, very …

Antibody-Dependent Enhancement Activity Of A Plant-Made Vaccine Against West Nile Virus, Amber M. Paul, Haiyan Sun, Dhiraj Acharya, Huafang Lai, Junyun He, Fengwei Bai, Qiang Chen

Publications

West Nile virus (WNV) causes annual outbreaks globally and is the leading cause of mosquito-borne disease in Unite States. In the absence of licensed therapeutics, there is an urgent need to develop effective and safe human vaccines against WNV. One of the major safety concerns for WNV vaccine development is the risk of increasing infection by related flaviviruses in vaccinated subjects via antibody-dependent enhancement of infection (ADE). Herein, we report the development of a plant-based vaccine candidate that provides protective immunity against a lethal WNV challenge mice, while minimizes the risk of ADE for infection by Zika (ZIKV) and dengue …

Strategies For The Improvement Of Healthcare Through Simulation, Roger C. Lankheet

Dissertations

Medical errors continue to plague the healthcare industry. The annual rates of morbidity are approximately 2.69 million (AHRQ, 2019), while mortality rates exceed 400,000 per annum (Makary & Daniel, 2016). There may be no panacea to combat these egregious rates. However, simulation of patient care events may better prepare healthcare professionals to prevent medical errors as it has been proven to be an effective learning strategy (Kirkham, 2018), enhancing skills while gaining experiential knowledge, without risk to actual patients.

The purpose of this qualitative study was to gain a better understanding of factors that impede or foster the frequent utilization …

Harnessing The Therapeutic Vulnerability Of Mmr Heterogeneity In Colorectal Cancer, Gayathri Anandappa, Michael J Overman

Faculty, Staff and Student Publications

In a recent issue of Cancer Cell, Amodio and colleagues report an interesting method of modulating immunosurveillance in colorectal tumors with DNA mismatch repair (MMR) heterogeneity.1 By pharmacologically enriching the MMR deficient (MMRd) component using 6-thioguanine, they demonstrate improved tumor control in murine models.

Biorisk Management, Laboratory Acquired Infections And Clinical Containment, Kashif Ali, Furqan Kabir, Esmeralda Meyer

Department of Paediatrics and Child Health

No abstract provided.

Climate Change, Human Health, And Resilience In The Holocene, Gwen Robbins Schug, Jane E. Buikstra, Sharon N. Dewitte, Brenda J. Baker, Elizabeth Berger, Michele R. Buzon, Anna M. Davies-Barrett, Lynne Goldstein, Anne L. Grauer, Lesley A. Gregoricka, Siân E. Halcrow, Kelly J. Knudson, Clark Spencer Larsen, Debra L. Martin, Kenneth C. Nystrom, Megan A. Perry, Charlotte A. Roberts, Ana Luisa Santos, Christopher M. Stojanowski, Jorge A. Suby, Daniel H. Temple, Tiffany A. Tung, Melandri Vlok, Tatyana Watson-Glen, Sonia R. Zakrzewski

Anthropology: Faculty Publications and Other Works

Climate change is an indisputable threat to human health, especially for societies already confronted with rising social inequality, political and economic uncertainty, and a cascade of concurrent environmental challenges. Archaeological data about past climate and environment provide an important source of evidence about the potential challenges humans face and the long-term outcomes of alternative short-term adaptive strategies. Evidence from well-dated archaeological human skeletons and mummified remains speaks directly to patterns of human health over time through changing circumstances. Here, we describe variation in human epidemiological patterns in the context of past rapid climate change (RCC) events and other periods of …