Digital Commons Network^™

Chinese Global Orders: Socialism, Tradition, And Nation In China-Russia Relations, William A. Callahan

Research Collection School of Social Sciences

While many use rational IR theory to explain Chinese foreign policy behavior, this paper follows global IR to employ interpretivist theory to examine how Chinese elites understand their country’s role in the world. In particular, it explores the Chinese global order ideas of socialism, tradition, and nation through a comparative analysis of how they work in China–Russia relations, especially after China’s 20th Communist Party Congress in 2022. The first section presents a critical analysis of the realist understanding of the China–Russia–U.S. strategic triangle. It argues that the socialist concept of “united front work” better explains Chinese (and Russian) policy in …

Reduced Heart Failure-Related Healthcare Costs With Furoscix Versus In-Hospital Intravenous Diuresis In Heart Failure Patients: The Freedom-Hf Study, Daniel Bensimhon, William S. Weintraub, William Frank Peacock, Tamas Alexy, Dalton Mclean, Donald C. Haas, Kathleen L. Deering, Stefanie J. Millar, Matthew M. Goodwin, John F. Mohr

Abington Jefferson Health Papers

Aim: Compare heart failure (HF) costs of Furoscix use at home compared with inpatient intravenous (IV) diuresis.

Patients & methods: Prospective, case control study of chronic HF patients presenting to emergency department (ED) with worsening congestion discharged to receive Furoscix 80 mg/10 ml 5-h subcutaneous infusion for ≤7 days. 30-day HF-related costs in Furoscix group derived from commercial claims database compared with matched historical patients hospitalized for <72 h.

Results: Of 24 Furoscix patients, 1 (4.2%) was hospitalized in 30-day period. 66 control patients identified and were well-matched for age, sex, ejection fraction (EF), renal function and other comorbidities. Furoscix patients had …

Protecting Natural Stewardship: Public Trusts, Wildlife Trusts, And The Effect Of Trophic Cascades, Nicholas Massey

Duke Journal of Constitutional Law & Public Policy

No abstract provided.

On Three Arguments Against Metaphysical Libertarianism, Ken Levy

Journal Articles

No abstract provided.

Chemistry And Biochemistry Affiliated Publications: Snapshot Of The Research Publications 2019-2022, Jeremy Smith, Lutishoor Salisbury

University Libraries Faculty Publications and Presentations

This report highlights the chemistry and biochemistry faculty publications for the period 2019-2022.

It include tables identifying the types of publications, the JCR ranking of the journals in which they published and a listing of their publications, etc.

The Influence Of Microorganisms On Human Health, Tiffany Bui

University Honors Theses

The purpose of this thesis is to explore the interplay between the environment, lifestyle, and composition of human microbiomes across different communities, with a specific focus on immune and digestive health. This literature review investigates three distinct types of communities: isolated/traditional, transitional, and urban/industrialized communities, each characterized by unique environments, societal structures, and interactions. These factors contribute to the distinct microbial populations and compositions within each community. It is impossible to avoid contact with microorganisms as they are present in every aspect of our lives, from the air we breathe, the water we drink, the soil we walk on, the …

(R2050) Dual Quaternion Matrices And Matlab Applications, Kemal Gökhan Nalbant, Salim Yüce

Applications and Applied Mathematics: An International Journal (AAM)

There are many studies in the literature on real quaternions and real quaternion matrices. There are few studies in the literature on dual quaternions. Definitions of the matrices of dual quaternions used in this study will be given. The originality of our research, the set of dual quaternion matrix we studied, will be defined for the first time in this study, and its properties will be given. Moreover, this study is critical because it is an applied study related to dual quaternion matrices. It will be easier to solve examples with large matrix sizes with MATLAB. People who use different …

Tree-Based Unidirectional Neural Networks For Low-Power Computer Vision, Abhinav Goel, Caleb Tung, Nick Eliopoulos, Amy Wang, Jamie C. Davis, George K. Thiruvathukal, Yung-Hisang Lu

Computer Science: Faculty Publications and Other Works

This article describes the novel Tree-based Unidirectional Neural Network (TRUNK) architecture. This architecture improves computer vision efficiency by using a hierarchy of multiple shallow Convolutional Neural Networks (CNNs), instead of a single very deep CNN. We demonstrate this architecture’s versatility in performing different computer vision tasks efficiently on embedded devices. Across various computer vision tasks, the TRUNK architecture consumes 65% less energy and requires 50% less memory than representative low-power CNN architectures, e.g., MobileNet v2, when deployed on the NVIDIA Jetson Nano.

A Diachronic, Scale-Flexible, Relational, Perspectival Operation: In Defense Of (Always-Reforming) Medium Specificity, Jordan Sjol

Film and Media Arts Faculty Publications

At least since Friedrich Kittler declared fiber-optic cable the “end of media,” there has been an idea in cinema and media studies that as all media become digital, the concept of medium specificity makes less and less sense. Meanwhile, many wonder if our field is coherent, as media scholars turn their attention to such objects as dust, cities, and whales. I argue that digital convergence makes medium specificity more rather than less vital, though in a reformed formulation. While our far-flung objects cannot cohere our discipline, a use of medium specificity as a diachronic, scale-flexible, relational, perspectival operation can.

Adverse Childhood Experiences(Aces) And Nonverbal Reasoning Skills, Monika Malinowska

Dissertations

Severe stress and interpersonal traumatic experience in childhood have a cascade effect on an individual's physical and mental health. There is evidence that people with complex adverse childhood experiences have diminished cognitive abilities. However, there are few studies on the effects of Adverse Childhood Experiences (ACE) on non-verbal reasoning skills. This study aimed to assess the relationships between ACEs, non-verbal reasoning skills, and academic achievement.

Parenting And Students' Gpa In The Latino Population: An Exploratory Study, Carolina Arboleda

Dissertations

The present study experimentally investigated Latino high school students’ grade point averages (GPA) and the parenting styles used by their parents based on Baumrind’s (1968, 1971, 1989, 1991) theory of parenting behaviors. Participants (N=52) were asked to take a survey of 62 questions total addressing three parenting dimensions as measured by the Escala Parental Breve to categorize their parents’ behaviors into parenting styles. Participants also responded to demographic questions such as English proficiency, household income, parents’ education level, and other relevant factors impacting parenting and GPA. Results from the study were limited as there was a limited number of participants; …

A Highly Selective Humanized Ddr1 Mab Reverses Immune Exclusion By Disrupting Collagen Fiber Alignment In Breast Cancer, Junquan Liu, Huai-Chin Chiang, Wei Xiong, Victor Laurent, Samuel C Griffiths, Jasmin Dülfer, Hui Deng, Xiujie Sun, Y Whitney Yin, Wenliang Li, Laurent P Audoly, Zhiqiang An, Thomas Schürpf, Rong Li, Ningyan Zhang

Faculty, Staff and Student Publications

BACKGROUND: Immune exclusion (IE) where tumors deter the infiltration of immune cells into the tumor microenvironment has emerged as a key mechanism underlying immunotherapy resistance. We recently reported a novel role of discoidin domain-containing receptor 1 (DDR1) in promoting IE in breast cancer and validated its critical role in IE using neutralizing rabbit monoclonal antibodies (mAbs) in multiple mouse tumor models.

METHODS: To develop a DDR1-targeting mAb as a potential cancer therapeutic, we humanized mAb9 with a complementarity-determining region grafting strategy. The humanized antibody named PRTH-101 is currently being tested in a Phase 1 clinical trial. We determined the binding …

Maternal Embryonic Leucine Zipper Kinase Is Associated With Metastasis In Triple-Negative Breast Cancer, Xuemei Xie, Gaurav B Chauhan, Ramakrishna Edupuganti, Takahiro Kogawa, Jihyun Park, Moises Tacam, Alex W Tan, Mohd Mughees, Fnu Vidhu, Diane D Liu, Juliana M Taliaferro, Mary Kathryn Pitner, Luke S Browning, Ju-Hyeon Lee, Yu Shen, Jian Wang, Naoto T Ueno, Savitri Krishnamurthy, Gabriel N Hortobagyi, Debu Tripathy, Steven J Van Laere, Geoffrey Bartholomeusz, Kevin N Dalby, Chandra Bartholomeusz

Faculty, Staff and Student Publications

UNLABELLED: Triple-negative breast cancer (TNBC) has high relapse and metastasis rates and a high proportion of cancer stem-like cells (CSC), which possess self-renewal and tumor initiation capacity. MELK (maternal embryonic leucine zipper kinase), a protein kinase of the Snf1/AMPK kinase family, is known to promote CSC maintenance and malignant transformation. However, the role of MELK in TNBC metastasis is unknown; we sought to address this in the current study. We found that

SIGNIFICANCE: These findings indicate that MELK is a driver of aggressiveness and metastasis in TNBC.

Enhancement Of Immunotherapies In Head And Neck Cancers Using Biomaterial-Based Treatment Strategies, Gemalene M Sunga, Jeffrey Hartgerink, Andrew G Sikora, Simon Young

Faculty, Staff and Student Publications

Head and neck squamous cell carcinoma (HNSCC) is a challenging disease to treat because of typically late-stage diagnoses and tumor formation in difficult-to-treat areas, sensitive to aggressive or invasive treatments. To date, HNSCC treatments have been limited to surgery, radiotherapy, and chemotherapy, which may have significant morbidity and often lead to long-lasting side effects. The development of immunotherapies has revolutionized cancer treatment by providing a promising alternative to standard-of-care therapies. However, single-agent immunotherapy has been only modestly effective in the treatment of various cancers, including HNSCC, with most patients receiving no overall benefit or increased survival. In addition, single-agent immunotherapy's …

Facial Analytics Based On A Coordinate Extrapolation System (Zface) For Morphometric Phenotyping Of Developing Zebrafish, Lorena Maili, Oscar E Ruiz, Philip H Kahan, Frankie Chiu, Stephen T Larson, S Shahrukh Hashmi, Jacqueline T Hecht, George T Eisenhoffer

Faculty, Staff and Student Publications

Facial development requires a complex and coordinated series of cellular events that, when perturbed, can lead to structural birth defects. A quantitative approach to quickly assess morphological changes could address how genetic or environmental inputs lead to differences in facial shape and promote malformations. Here, we report on a method to rapidly analyze craniofacial development in zebrafish embryos using facial analytics based on a coordinate extrapolation system, termed zFACE. Confocal images capture facial structures and morphometric data are quantified based on anatomical landmarks present during development. The quantitative morphometric data can detect phenotypic variation and inform on changes in facial …

Neuroaffective Reactivity Profiles Are Associated With Vulnerability To E-Cigarette Use, Francesco Versace, George Kypriotakis, Dustin Pluta

Faculty, Staff and Student Publications

BACKGROUND: We tested whether neuroaffective responses to motivationally salient stimuli are associated with vulnerability to cue-induced e-cigarette use in e-cigarette naïve adults who smoke daily. We hypothesized that individuals with stronger neuroaffective responses to nicotine-related cues than to pleasant stimuli (the C>P reactivity profile) would be more vulnerable to cue-induced nicotine self-administration than individuals with stronger neuroaffective responses to pleasant stimuli than to nicotine-related cues (the P>C reactivity profile).

METHODS: We used event-related potentials (ERPs, a direct measure of cortical activity) to measure neuroaffective reactivity to pleasant, unpleasant, neutral, and nicotine-related cues indicating the opportunity to use an …

Trpv4 Expression In The Renal Tubule Is Necessary For Maintaining Whole Body K+ Homeostasis, Anna Stavniichuk, Kyrylo Pyrshev, Oleg Zaika, Viktor N Tomilin, Mariya Kordysh, Monika Lakk, David Križaj, Oleh Pochynyuk

Faculty, Staff and Student Publications

The Ca2+-permeable transient receptor potential vanilloid type 4 (TRPV4) channel serves as the sensor of tubular flow, thus being well suited to govern mechanosensitive K+ transport in the distal renal tubule. Here, we directly tested whether the TRPV4 function is significant in affecting K+ balance. We used balance metabolic cage experiments and systemic measurements with different K+ feeding regimens [high (5% K+), regular (0.9% K+), and low (<0.01% K+)] in newly created transgenic mice with selective TRPV4 deletion in the renal tubule (TRPV4fl/fl-Pax8Cre) and their littermate controls (TRPV4fl/fl). Deletion was verified by the absence of TRPV4 protein expression and lack of TRPV4-dependent Ca2+ influx. There were no differences in plasma electrolytes, urinary volume, and K+ levels at baseline. In contrast, plasma K+ levels were significantly elevated in TRPV4fl/fl-Pax8Cre mice on high K+ intake. K+-loaded knockout mice exhibited lower urinary K+ levels than TRPV4fl/fl mice, which was accompanied by higher aldosterone levels by day 7. Moreover, TRPV4fl/fl-Pax8Cre mice had more efficient renal K+ conservation and higher plasma K+ levels in the state of dietary K+ deficiency. H+-K+-ATPase levels were significantly increased in TRPV4fl/fl-Pax8Cre mice …

Smooth Muscle-Alpha Actin R149c Pathogenic Variant Downregulates Integrin Recruitment At Cell-Matrix Adhesions And Decreases Cellular Contractility, Krishna R Ojha, Hyoseon Kim, Samuel Padgham, Laura Hopkins, Robert J Zamen, Abhijnan Chattopadhyay, Gang Han, Dianna M Milewicz, Michael P Massett, Andreea Trache

Faculty, Staff and Student Publications

Thoracic aortic aneurysm is found in patients with ACTA2 pathogenic variants. ACTA2 missense variants are associated with impaired aortic smooth muscle cell (SMC) contraction. This study tested the hypothesis that the Acta2R149C/+ variant alters actin isoform expression and decreases integrin recruitment, thus, reducing aortic contractility. Stress relaxation measurements in thoracic aortic rings showed two functional regimes with a reduction of stress relaxation in the aorta from Acta2R149C/+ mice at low tension, but not at high tension values. Contractile responses to phenylephrine and potassium chloride were 50% lower in Acta2R149C/+ mice than in wild-type (WT) mice. Additionally, SMC were immunofluorescently labeled …

Ocular Toxicity Profile Of Targeted Cancer Therapy (Tct) At A Us Tertiary Cancer Center, Moe Ameri, Nagham Al Zubidi, Azadeh Razmandi, Andrew Whyte, Aung Naing, Nimisha A Patel, Dan S Gombos

Faculty, Staff and Student Publications

PURPOSE: Targeted cancer therapy (TCT) is a significant advancement in oncology with promising survival improvement in patients with cancer and remarkable effects on various cancers. There is evidence suggesting a connection between specific TCT classes and the occurrence of immune-related adverse events (irAEs). Our study aims to investigate the potential ocular toxicities of different classes of TCT, provide a better understanding of these toxicities, and aid in the future development of screening and management recommendations for ocular irAEs.

DESIGN: Retrospective observational case series.

PARTICIPANTS: Only ocular immune-related AEs were included in the study; patients on TCT who received a new …

Metamaterial-Based Soft Actuators, Savannah June Cheney, Nathan Kessenich, Marco Leen, Merek Mcgill

Mechanical Engineering

For this project the team was tasked with designing a soft actuator that incorporated aspects of mechanical metamaterials. The team’s goal was to demonstrate the feasibility of structural metamaterials in the field of soft robotics and demonstrate a novel response with a final assembly. Also included in the team's discussion are the manufacturing steps, protype tests & results, and suggested future next steps. Following the previous report (critical design review) the team chose to follow the path of designing a continuum robot with metamaterials incorporated into the design. A continuum robot consists of a soft cylindrical body with rigid evenly …

Zero-Waste Ocean Floor Hydrophone Mooring, Chloe Schofield, German Jack Ellsworth, Jathun Somasundaram, Evan Brown

Mechanical Engineering

Maddie Schroth-Glanz, from the Statistics Department of Cal Poly, requires a system that assists in the deployment and retrieval of a marine hydrophone used to record ocean mammal vocalization patterns, specifically in large whales. This report discusses the final design, including changes to the design after the Critical Design Review, and the tests that were done to ensure the final design achieves the specifications of the project. We will discuss everything from material purchases to manufacturing and assembly for all subsystems of the project, and then discuss how our testing justified the design choices we made. Finally, the report will …

Therapeutic Mechanical Horse Project, Broghan Martin, Carson Roff, Zach Barnisham, Lydia Barnes

Mechanical Engineering

This project team created a simple mechanical model of a horse that disabled children could ride on to feel more comfortable partaking in equine therapy. This project was sponsored by Jack’s Helping Hand as part of their equine therapy program. The team went through the entire design process of researching, ideating, prototyping, and testing to create the final product. Finite element analysis of the structural members of the horse was performed. The forces used in that model were later validated through testing of the strength of those same members after manufacturing. In the end, a self-actuating single degree of freedom …

Disc Golf Throwing Robot, Nevada S. Schultz, Sydney M. Lewis, Erick Edmundo Daza, Rachel Alysse Greenberg, Peter M. Kean

Mechanical Engineering

Disc golf companies need better methods to test disc flight. The scope of this project is to create a disc throwing robot that can throw a disc golf driver 450-500 feet, with control over the speed, spin, and release angle. Research shows that multiple disc-throwing products exist; however, none meet the full requirements of this project. The Cal Poly senior project design team created a proof-of-concept machine. This prototype started as a two-wheel mechanism. Eventually, a third wheel was added, allowing for complete control over disc spin. The three-wheel prototype reached 62 mph when perfectly calibrated. The prototype is accurate, …

Reformed Worship (Rw) 148 - Justice (June 2023), Reformed Worship Editors

Reformed Worship Magazine

Editorial: It Starts with the Land by Joyce Borger....2

Worship Series: The Art of Neighboring by Laura de Jong....3

Creation Care, Coal, and the Greatest Commandment by Kyle Meyaard-Schaap....11

A Prayer for the Flourishing of Bees by Joyce Borger....14

The Season of Creation by Rachel Mash and Suzana Moreira....15

Singing Creation by Debra and Ron Rienstra....20

Being a Good Guest by Adrian Jacobs....26

The Land We Stand On by Sam Cooper, Janina Krabbe, Silas Krabbe, and Jacqui Mignault....33

God Is a Homemaker by Jessica Maddox....40

For Pastors: To Preach Justice by …

Home Based Business Ordinance For The City Of Reno, Maxwell Hp Johnson

City and Regional Planning

Home based businesses allow for some commercial and business activities to occur within private residences by residents without the need of commercially zoned properties or structures. Home based businesses provide affordable accommodation for less impactful small businesses, but can additionally impact neighbors and communities with negative externalities when not properly regulated. The City of Reno, Nevada currently faces rising land prices and limited availability of commercial properties. Such conditions increase the adoption of home based businesses, and combined with the lack of regulation can create nuisances within communities.

The ordinance proposal analyzes relevant legal cases, case study ordinances, and the …

The Guardian The Month Of June 2023, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the Month of June 2023. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.

Ipulse: June 2023, Lynn University

Student Newspapers

Issue:

• June 2023 [Summer Week #1]: A Campus Transformation for the Ages - All of Them; The Story Behind the Flags; In the Center of Campus: A Wellness Center Coming Soon; An Unforgettable Summer; Shining Knights of Boca; Lynn is a Hotbed for Sports Media; Summer Comes, Students Go; Lynn to the Max

Fraught Aging And Frayed Social Networks, Laura Zimmer-Tamakoshi

Pacific Studies

This article looks at the challenges of aging in Gende society and why the Papua New Guinea government should consider a safety net for more vulnerable populations. It begins with an overview of how the Gende used their exchange system over many generations to deal with periods of extreme uncertainty and inequality. Investing in a moral economy that encouraged gender equality and expansive kin relations and obligations, the Gende weathered tribal warfare that drove them off their traditional lands long ago. Moving into sparsely populated mountains in what is now Madang Province, Gende became middlemen in trade routes connecting the …

Analysis Of Research Papers On The Use Of English Movies In Chinese Senior High School English Teaching In The Past Three Years, Peiyuan Lin, Hong Mei

Journal of Educational Technology Development and Exchange (JETDE)

Much attention has been paid to using English movies in senior high school English teaching in China since the release of 2017 edition of Senior High School English Curriculum Standards that lists English Movie Appreciation as an optional compulsory course. Senior high school teachers have conducted substantial research over the past three years regarding the practical application of English movies in their teaching, yet there has been a lack of thorough and systematic of analysis of the large number of relevant papers published, which, more or less, limits the understanding and further advancements of this study area. This paper attempts, …

A Randomized Clinical Trial Of Behavioral Activation And Exposure-Based Therapy For Adults With Generalized Anxiety Disorder., Hannah Berg, Elisabeth Akeman, Timothy J. Mcdermott, Kelly T. Cosgrove, Namik Kirlic, Ashley Clausen, Mallory Cannon, Hung-Wen Yeh, Evan White, Wesley K. Thompson, Emily M. Choquette, Cassandra A. Sturycz-Taylor, Gabe Cochran, Sam Ramirez, Christopher R. Martell, Kate B. Wolitzky-Taylor, Michelle G. Craske, James L. Abelson, Martin P. Paulus, Robin L. Aupperle

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVE: Exposure-based therapy (EXP) and behavioral activation (BA) are empirically-supported behavioral intervention techniques that target avoidance and approach behavior to alleviate symptoms. Although EXP is an established treatment for generalized anxiety disorder (GAD), the effectiveness of BA for GAD has not been directly tested or compared with that of EXP. This study examined the efficacy of EXP and BA for adults with GAD.

METHOD: In a randomized clinical trial (clinicaltrials.gov: NCT02807480) with partial blinding in Tulsa, OK, 102 adults with GAD were allocated to manualized, 10-session EXP or BA between April 2016-April 2021. Primary analyses were intention-to-treat and included the …