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Effect Of Type Of Tree Leaves On Intake, Nutrient Utilisation And Rumen Fermentation Pattern In Goat Fed With Cenchrus Ciliaris Grass, S. Singh, S. S. Kandu, L. K. Karnani

IGC Proceedings (1977-2023)

Grasses and tree leaves/shrubs are the major feeds available from grasslands and grazing fields. There is though a dearth of information on the nutritional value of tree foliage although available information was collated by Shelton et al. (1995). This study evaluated the relative nutritive value of two foliages for goats.

Ensiling Characteristics And Nutritive Value Of Browse/Maize Forage Mixtures, F. B. Bareeba, H. Kato, Elly N. Sabiiti

IGC Proceedings (1977-2023)

The practice of growing fodder tree and shrubs is being advocated for and adopted in smallholder dairy production systems. In Uganda, Calliandra calothyrsus, Gliricidia sepium, and Leucaena leucocephala have been identified and recommended as the most suitable species (Sabiiti, 2001). However tree foliage contains toxic compounds (Lowry, 1990), which may be alleviated by ensiling. The objective of the experiment was to study the ensiling characteristics of browse/ maize forage mixtures and their nutritive value when fed to lactating dairy cows.

The Effect Of Fermentation Of Calliandra Calothyrsus, Gliricidia Sepium, Leucaena Leucocephala And Maize Forage On Rumen Degradation And Microbial Protein Synthesis, H. Kato, F. B. Bareeba, Elly N. Sabiiti, C. Ebong

IGC Proceedings (1977-2023)

Ensiling as a means of storing green fodder by acidification has a profound effect on the chemical composition of the resultant silage. Ensiling could therefore, ameliorate the effects of anti-nutritional factors associated with browses. The objective of the experiment was to determine fermentation characteristics and rumen degradation (D) of ensiled Calliandra calothyrsus (C), Gliricidia sepium (G), Leucaena leucocephala (L) and maize forage.

Persistence Of Tall Fescue And Cattle Grazing Preference As Affected By Endophyte Status, D. J. Lang, S. P. Wang, A. Tokilita, R. Given, M. Salem, R. Elmore

IGC Proceedings (1977-2023)

Endophyte-infected (E+) grasses often exhibit increased survival, growth and resistance to herbivory compared to uninfected counterparts. Latch (1997) proposed a strategy for cultivar improvement of infecting elite cultivars with strains of Neotyphodium coenophialum that are non-toxic to livestock, but still able to convey the persistence advantage shown with wild-type, toxic endophyte. The strategy of re-infecting tall fescue (Lolium arundinaceum (Schreb.) Darbysh.) cultivars with naturally occurring, non-ergot-producing endophytes appears promising for removing animal toxicity symptoms and retaining agronomic performance (Bouton et al., 2002; Hill et al., 2002). The objective of this study was to compare the effect of …

Performance Of Animals Grazing Various Tall Fescue / Endophyte Combinations, Andrew A. Hopkins

IGC Proceedings (1977-2023)

Endophyte (Neotyphodium coenophialum) infection can improve tall fescue persistence (Read & Camp, 1986), but animals grazing wild type tall fescue often suffer from reduced performance and poor health (Hoveland et al., 1983). Novel endophytes do not produce the alkaloids implicated in animal toxicity and can help maintain stand longevity while minimizing animal health problems (Bouton et al., 2002). The objectives of this research were to compare productivity and health of animals grazing various tall fescue / endophyte combinations, and the persistence of these combinations under grazing in the Southern Plains of the USA.

Recovery Of Yearling Calves From Fescue Toxicosis, G. E. Aiken, M. L. Looper, S. F. Tabler, J. R. Strickland

IGC Proceedings (1977-2023)

Tall fescue (Lolium arundinaceum (Schreb.) S.J. Darbyshire) is widely utilized for grazing in the transition zone between the temperate and subtropical regions of the eastern U.S.A. Cattle grazing tall fescue frequently exhibit fescue toxicosis, a malady caused by consumption of toxins produced by the endophyte, Neotyphodium coenophialum. Symptoms of fescue toxicosis include retention of rough hair coat, increased body temperature and laboured respiration. Heat stress may be severe at onset of high ambient temperature and humidity. Transporting cattle exhibiting toxicosis can therefore be difficult because combined stresses of the toxicosis and transporting often result in high mortality. An experiment …

Reduce Tall Fescue Toxicosis In Festuca Arundinacea Forage Systems With Legumes, J. C. Waller, A. E. Fisher, H. A. Fribourg, C. J. Richards

IGC Proceedings (1977-2023)

Tall fescue (Lolium arundinaceum = Festuca arundinacea) is an important cool-season grass because of persistence and spring and autumn productivity. Most existing tall fescue pastures in Tennessee are Kentucky-31 (KY-31) and are infested with the endophytic fungus Neotyphodium coenophialum that causes tall fescue toxicosis. Symptoms in beef cattle include reduced rates of gain, poor conception rates, decreased dry matter intake, a long rough haircoat in summer, and very low serum prolactin. Earlier studies indicated that the performance of cattle grazing endophyte-free (EF) tall fescue is superior to that of cattle grazing endophyte-infected (EI) tall fescue (Fribourg et al …

Milk Production From Cows Grazing Perennial Ryegrass Pastures Infected With Wild Or Ar1 Endophyte In New Zealand, Stephanie J. Bluett, E. R. Thom, D. A. Clark

IGC Proceedings (1977-2023)

Most perennial ryegrass (Lolium perenne) cultivars in New Zealand are available with either the natural wild endophyte (Neotyphodium lolii); the AR1 novel endophyte (no lolitrem B or ergovaline production); or endophyte-free. Although wild endophyte protects ryegrass against insect attack, improving pasture persistence, it can also cause ryegrass staggers and reduced animal performance. Endophyte AR1 does not cause ryegrass staggers but still protects against insect pests such as Argentine stem weevil (Listronotus bonariensis). A 3-year farmlet experiment was carried out to evaluate the effects of AR1 and wild endophyte-infected ryegrass on pasture performance, milk production …

The Effects Of Exposure To Endophyte-Infected Tall Fescue Seed On Faecal And Urine Concentrations Of Ergovaline And Lysergic Acid In Mature Gelding Horses, C. L. Schultz, S. L. Lodge-Ivey, A. M. Craig, James R. Strickland, L. P. Bush

IGC Proceedings (1977-2023)

Despite the good nutritive value of endophyte-infected tall fescue, consumption by livestock results in a decrease in both reproductive and growth performance due to ergot alkaloids produced by an endophytic fungus (Cross et al., 1995). Little research has investigated the metabolic fate of ergot alkaloids and/or their metabolites in grazing horses. Thus, the objectives of this experiment were: a) to determine concentrations of ergovaline (EV) and lysergic acid (LA) in the faeces and urine of geldings exposed to tall fescue seed over a time course experiment and b) to measure the effects of alkaloid-containing tall fescue on nutrient digestibility …

Ergovaline And Ergovalinine And Tall Fescue Content Of Pastures In Central Kentucky, P. W. Long, Jimmy C. Henning, L. P. Bush

IGC Proceedings (1977-2023)

Kentucky has > 2Mha of tall fescue (Festuca arundianacea Schreb.) grown mainly for livestock consumption. Many alkaloids in tall fescue are produced in a mutualistic association between tall fescue and an endophytic fungus (Neotyphodium coenophialum) (Long et al., 2002). Ingestion of tall fescue by livestock may depress reproduction and growth (Schultz & Bush, 2002). Not all Kentucky fields of tall fescue are thought to be infected with endophyte, but forage samples from all surveyed pastures had measurable ergopeptine alkaloids. Therefore, it is reasonable to assume that some of the tall fescue plants in these fields were infected. …

A Study In Cuba Of The Biology, Ecology And Agroecological Management Of Heteropsylla Cubana Crawford In Leucaena Leucocephala (Lam.) De Wit, N. Valenciaga, M. Felicia Díaz, T. E. Ruíz, M. Fernández, C. Mora

IGC Proceedings (1977-2023)

As a consequence of the increase in Leucaena leucocephala areas to counter the shortage of feed in Cuban cattle production, there is a risk of the development of Heteropsylla cubana Crawford (Hemiptera: Psyllidae) as a pest in silvopastoral systems with this legume. This psyllid is known to be the main phytophagous pest (Valenciaga, 2003), which produces damage in 95% of the apical region of branches. Since information on the identification and biology of a pest species is a necessary prerequisite for its management, a taxonomic, biological and ecological study was conducted to define Heteropsylla behaviour in Cuban conditions and elaborate …

Fodder Shrubs For Improving Incomes Of Dairy Farmers In The East African Highlands, Steven Franzel, C. Wambugu, J. Stewart, J. Cordero, B. D. Sande

IGC Proceedings (1977-2023)

Smallholder dairying is an important enterprise in the highlands of E Africa. Farm sizes average 1-2ha and zero-grazing, cut-and-carry systems predominate. Inadequate protein reduces milk production and forces many farmers to spend scarce cash on commercial dairy meal supplements. In 1991, on-farm trials on fodder shrubs were started in Embu District as a collaborative venture of the Kenya Agricultural Research Institute, the Kenya Forestry Research Institute, and the World Agroforestry Centre. Calliandra calothyrsus was released to farmers in 1995 and was followed by Leucaena trichandra, mulberry (Morus alba), and Sesbania sesban. Farmers produce seedlings of calliandra …

Stylo In India: Much More Than A Plant For The Revegetation Of Wasteland, C. R. Ramesh, S. Chakraborty, P. S. Pathak, Nagaratna Biradar, P. Bhat

IGC Proceedings (1977-2023)

Since the 1950s introductions of Stylosanthes scabra, S. hamata and S. guianensis from Australia, South America, the USA and Africa have continued in India. Although no cultivar has been released, selections of S. scabra, S guianensis and S. hamata are used in a range of environmental and commercial production systems. A large seed industry spanning >400 ha and run by >600 smallholder farmers producing 800t seeds/ year supports this usage (Rao et al., 2004). Stylo is mainly used in India for revegetation of wastelands where it reduces soil erosion and offers fodder for livestock (Pathak et al …

Leucaena In Northern Australia: A Forage Tree Legume Success Story, B. F. Mullen, H. M. Shelton, Scott A. Dalzell

IGC Proceedings (1977-2023)

Leucaena leucocephala (leucaena) is a long-lived, perennial forage tree legume of very high nutritive value for ruminant production. In northern Australia, leucaena is direct seeded into hedgerows 5-10m apart, with grass species such as buffel grass (Cenchrus ciliaris) planted in the inter-row to form a highly productive and sustainable grass-legume pasture that cattle graze directly. It generally is grown on deep, fertile soils in sub-humid environments with average rainfall of 600-800mm/year. Steer gains of 275-300kg/head per year are achieved, with short-term daily gains over the main growing season > 1kg/head. Being very deep-rooted, leucaena exploits moisture beyond the reach …

Aeschynomene And Carpon Desmodium: Legumes For Bahiagrass Pasture In Florida, Lynn E. Sollenberger, R. S. Kalmbacher

IGC Proceedings (1977-2023)

Soils and climate are very diverse across Florida, and no single legume has state-wide adaptation. However, aeschynomene (Aeschynomene americana), an annual, and carpon desmodium (Desmodium heterocarpon) cv. Florida, a perennial, are the most commonly used legumes for grazing on the central and southern peninsula, which produces 65% of Florida's beef calves. Both grow well with bahiagrass (Paspalum notatum), which is the main pasture grass, with ~1M ha state-wide. Circa 65K ha of bahiagrass contain at least limited quantities of aeschynomene and 14K ha contain carpon desmodium.

Forage Quality Of Cool Season Pasture Species Under Two Rotational Grazing Height Regimes, H. D. Karsten, M. Carlassare

IGC Proceedings (1977-2023)

To optimize animal and pasture performance in management intensive grazing systems, pasture production and quality often must be compromised. Rotationally-stocking pastures at slightly taller grazing heights can increase pasture productivity, but lower forage quality may limit animal performance. Our objective was to compare the forage quality of common cool season pasture species in the Northeastern U.S., under two rotational grazing regimes defined by slightly different grass heights.

The Role Of Footwear, Foot Orthosis And Training-Related Strategies In The Prevention Of Bone Stress Injuries: A Systematic Review And Meta-Analysis, Alexandre Lavigne, Dominic Chicoine, Jean-François Esculier, François Desmeules, Pierre Fremont, Blaise Dubois

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 721-743, 2023. Objective: To evaluate the effectiveness of footwear, foot orthoses and training-related strategies to prevent lower extremity bone stress injury (BSI). Design: Systematic review and meta-analysis. Data sources: Four bibliographic databases (from inception until November 2021): Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and CINAHL. Eligibility criteria: Randomised controlled trials (RCTs) that assessed the risk of developing a BSI when using particular footwear, foot orthoses or training-related strategies such as muscle strengthening, stretching, and mechanical loading exercises. Results: Eleven studies were included in this systematic review. When wearing foot orthoses, the risk …

The Work Of Pioneering Amish Studies Scholar Walter Kollmorgen: Annontations Of His 1940s Amish Publications, Cory Anderson

Journal of Amish and Plain Anabaptist Studies

Walter Kollmorgen’s two seminal contributions to Amish studies scholarship include the 1942 report “Culture of a Contemporary Rural Community: The Old Order Amish of Lancaster County, Pennsylvania” published by the U.S. Department of Agriculture’s Bureau of Agricultural Economics, and his 1943 article “The Agricultural Stability of the Old Order Amish and Old Order Mennonites of Lancaster County, Pennsylvania” published in the American Journal of Sociology. His 1942 report was one of six mixed-methods studies that analyzed the relative in/stability of rural American communities during the Great Depression. The six-part series concluded that the Amish of Lancaster County, PA, weathered the …

The Life Of Pioneering Amish Studies Scholar Walter Kollmorgen: Transcript Of The Reschly-Jellison Interviews, Steven Reschly, Katherine Jellison

Journal of Amish and Plain Anabaptist Studies

On March 20, 1994, we interviewed Walter Kollmorgen. Reschly also conducted a follow-up interview March 8, 1995. Herein, we provide the transcripts of these interviews, which are of particular historical value since Kollmorgen was one of Amish studies’ first researchers. Kollmorgen was a native speaker of German from having grown up in a Lutheran family in rural Nebraska. He and his younger sister, Johanna, both contracted polio at a very young age. The combination of German and physical limitations enabled both to establish rapport in a short time with the Amish community in Lancaster County for his rural community study. …

Subjectivity In The Lancaster Amish Community Study Of 1940-42: 'Economic Conquest' In Loomis’S Diary And Rosinow’S Photographs, Elizabeth Bennett

Journal of Amish and Plain Anabaptist Studies

The American Farm Community Study (1940), funded by the USDA’s Bureau of Agricultural Economics, was a social investigation that sought to determine why some rural communities thrive while others fail. To conduct the Study, the Bureau sent social scientists to six rural communities across the country to investigate and document the most and least “stable” American communities. Geographer Walter Kollmorgen, sociologist Charles Loomis, and photographer Irving Rusinow documented the Old Order Amish of Lancaster County, PA, as the “most stable” community in the Study. In Lancaster, the men found a people thriving in the midst of english neighbors still economically …

А Review Of Heterometrus In Thailand (Scorpiones: Scorpionidae), Kazusa Kawai, Thornthan Unnahachote, Yossaphon Suttisatid, Victoria Tang

Euscorpius

Five species of the genus Heterometrus Ehrenberg, 1828 are currently confirmed from Thailand and revised, with their respective distribution range in this country updated. Heterometrus laevigatus (Thorell, 1876) is considered a nomen dubium, while its two previous junior synonyms, H. cimrmani Kovařík, 2004, stat. rev. and H. minotaurus Plíšková et al., 2016, stat. rev. are revalidated and redescribed based on the examination of topotypes. Females of H. minotaurus Plíšková et. al., 2016, stat. rev. were also collected and examined, and their characters are herein described with a special attention to sexual dimorphism. Furthermore, some populations previously regarded as H. …

The Technology Of Manufacturing Fuel For Oil Lamps In The Hellenistic Period: An Applied Study Through The Findings Of The Alexandria Necropolis Project Of Shatby, Alexandria [2020–2023], Ibrahim H. M. Ibrahim, Ahmed A. A. Settawy

Journal of the General Union of Arab Archaeologists

تكنولوجيا صناعة وقود إضاءة المسارج بالعصر الهلينستي «دراسة تطبيقية من خلال مكتشفات مشروع جبانة الشاطبي بالإسكندرية

2020-2023 [Ar]

يقدم هذا البحث دراسة تطبيقية وتجريبية لما تم الكشف عنه من بقايا مادة وقود الإضاءة التى كانت تستخدم للمسارج فى الفترة الهلّينستية، وكذلك دراسة بقايا لفتيل محترق عثر عليه ضمن مشروع ترميم وتطوير وحماية جبانة الشاطبى الأثرية، والذى نفذته جمعية الآثار بالإسكندرية بتمويل من مؤسسة أ.ج. لفنتيس القبرصية فى الفترة من 2020-2023م. تضمن المشروع إعادة استكشاف الجبانة الأثرية بإزالة الرديم المتراكم بها عبر الزمن. وجادت الجبانة بالعديد من القطع الأثرية تمثلت فى مسارج وأطباق فخارية وأوانى الحضرة وبقايا عظام …

Assessing Conservation Treatments Of The Main Façades Of Medinet Habu Temple, Luxor–Egypt, Ahmed Manci

Journal of the General Union of Arab Archaeologists

تقييم علاج وصيانة الواجهات الرئيسية لمعبد مدينة هابو، الآقصر – مصر [Ar]

تُركز هذه الورقة على المخاطر البيئية التي تؤثر على النقوش الجدارية بالواجهات الرئيسية للمعبد الجنائزي لرمسيس الثالث بالضفة الغربية للأقصر مع اقتراح أفضل المواد لحفظ هذه النقوش. لتحقيق هذا الغرض، تمت دراسة مواد البناء المستخدمة في المعبد، ونواتج التلف، والعوامل البيئية المحيطة. تم تحديد خصائص المواد من خلال الفحص البصرى، والميكروسكوب المستقطب، والميكروسكوب الإلكترونى الماسح المزود بوحدة التحليل العنصرى للأشعة السينية، وحيود الأشعة السينية (XRD)، وقياس التغيرات اللونية، وقياس زاوية التلامس مع الماء الثابت، مع تحديد بعض الخصائص الفيزيائية والميكانيكية. أظهرت النتائج أن النقوش الجدارية …

Late Middle Kingdom Funerary Stela Of Intf Iqr Anxw At The British Museum (Ea563), Bassem Mohamed

Journal of the General Union of Arab Archaeologists

[Ar] لوحة جنائزية من أواخر الأسرة الثانية عشرة لأنتف إقر عنخو

تعود هذه اللوحة الجنائزية قيد الدراسة إلى إنتف إقرعنخو والذي كان حامل ختم ملك مصر السفلى، أمين الملك وخزانةDd-bAw ، وهي معروضة الآن في المتحف البريطاني، وفقًا لأحمد فخري وبورتر موس فقد كانت هناك لوحة جرانيتية أخرى تعود لنفس مالك هذه اللوحة مع اسم والدته مؤرخة بالعام الثالث عشر من حكم سنوسرت الثالث في وادي الهودي، ووفقً Ilin-Tomich. ، فإن صيغة حتب دي نسو تشير إلى أن تاريخها يعود إلى نهاية الأسرة الثانية عشرة، وبمقارنة هذه اللوحة مع لوحات أخرى من نفس الفترة من حيث أسلوب الكتابة والقاب المالك …

A Portrait Of A Ptolemaic Prince From Kom El-Louli, Ahmed Derbala, Sayed ʿAbdel Malik ʿAbd El Hamid

Journal of the General Union of Arab Archaeologists

صورة شخصية لأمير بطلمي من كوم اللولي [Ar]

صورة شخصية من المرمر لصبي صغير غير منشورة، عُثر عليها بحفائر البعثة المصرية بمنطقة كوم اللولي الأثرية بتونا الجبل، الرأس بالحجم الصغير ويوجد بها تدمير بالجزء الايمن للوجه، ويُعتقد أنها تخص أحد الأمراء في نهاية العصر البطلمي خلال القرن الأول ق.م، نظرا لأسلوب تصفيف الشعر والعصابة المربوطة أعلى الجبهة والاجزاء المتبقية من ملامح الوجه. ويحاول الباحثان تحديد الفترة الزمنية التي تنتمي إليها هذه الصورة الشخصية، وأيضا محاولة تحديد هوية صاحبها بناءً على مقارنة الملامح الشخصية والخصائص الفنية مع الأمثلة المشابهة له.

[En] The current paper proposes hypotheses the dating and identity of …

Using Lanthanide Ions As Magnetic And Sensing Probes For The Detection Of Tetracycline From Complex Samples, Yan-Cen Zhan, Chin-Poa Chiu, Yu-Chie Chen

Journal of Food and Drug Analysis

Tetracycline (TC) is a broad-spectrum antibiotic and has been added to animal feeds to grow livestock under healthy conditions, making it important to have effective methods for rapidly detecting TC in complex samples. In this study, a novel method that uses lanthanide ions (i.e. Eu³⁺ and Gd³⁺) as magnetic and sensing probes for the detection of TC from aqueous samples is explored. When dissolving Gd³⁺ in tris(hydroxymethyl)aminomethane (Tris) buffer at pH 9, magnetic Gd³⁺-Tris conjugates can be readily generated. The magnetic Gd³⁺-Tris conjugates possess trapping capacity toward TC from sample solutions via …

Urolithin A Exhibits A Neuroprotective Effect Against Alzheimer’S Disease By Inhibiting Dyrk1a Activity, Huang-Ju Tu, Chih-Jou Su, Chao-Shiang Peng, Tony Eight Lin, Wei-Chun Huang Fu, Kai-Cheng Hsu, Tsong-Long Hwang, Shiow-Lin Pan

Journal of Food and Drug Analysis

Alzheimer’s disease (AD) is a devastating neurodegenerative disease with more than 50 million people suffer from it. Unfortunately, none of the currently available drugs is able to improve cognitive impairment in AD patients. Urolithin A (UA) is a metabolite obtained from ellagic acid and ellagitannin through the intestinal flora, and it has antioxidant and anti-inflammatory properties. Previous reports found that UA had neuroprotective effects in an AD animal model, but the detailed mechanism still needs to be elucidated. In this study, we performed kinase-profiling to show that dual-specific tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is the main target of UA. Studies …

Resveratrol Stimulates Star Expression And Progesterone Production By Gper-Mediated Downregulation Of Snail Expression In Human Granulosa Cells, Tinglin Song, Jiaye Chen, Sizhu Yang, Boqun Liu, Lingling Zhang, Qian Zhang, Jung-Chien Cheng, Lanlan Fang

Journal of Food and Drug Analysis

Steroidogenic acute regulatory protein (StAR) plays a critical role in the regulation of progesterone (P4) production. Resveratrol (RSV), a natural polyphenol, has beneficial effects on reproductive function. However, its effects on StAR expression and P4 production in human granulosa cells remain undetermined. In this study, we showed the treatment of RSV upregulated StAR expression in human granulosa cells. G protein-coupled estrogen receptor (GPER) and ERK1/2 signaling were involved in RSV-stimulated StAR expression and P4 production. In addition, the expression of a transcriptional repressor, Snail, was downregulated by RSV, which contributed to the RSV-induced induction of StAR expression and P4 production.

Development Of A Lateral Flow Immunoassays-Based Method For The Screening Of Ractopamine In Foods And Evaluation Of The Optimal Strategy In Combination Of Screening And Confirmatory Tests, Yuan-Chih Chen, Jen-Yi Hsu, Chien-Sheng Chen, Yi-Ting Chen, Pao-Chi Liao

Journal of Food and Drug Analysis

Ractopamine has been authorized as a feed additive and permitted in animal husbandry. With the establishment of the regulation to limit the concentration of ractopamine, a rapid screening method for ractopamine is urgently needed. Additionally, how to combine the screening and confirmatory tests of ractopamine is also critical to maximizing the efficiency of testing. Here, we developed a lateral flow immunoassays-based method for the screening of ractopamine in foods and proposed a cost-benefit analysis approach to optimize cost allocation between screening and confirmatory tests. After verifying the analytical and clinical performance of the screening method, a mathematical model was established …

Sleep-Promoting Activity Of Amylase-Treated Ashwagandha (Withania Somnifera L. Dunal) Root Extract Via Gaba Receptors, Chun Woong Park, Ki-Bae Hong, Hyung Joo Suh, Yejin Ahn

Journal of Food and Drug Analysis

Ashwagandha (Withania somnifera L. Dunal), an Indian medicinal plant that has been used for centuries to treat insomnia, exhibits a variety of biological activities, such as improving cognitive function, immunity and anxiety. In this study, the effect of enzyme-treated Ashwagandha root extract (EA) and on sleep was evaluated using rodent models. Starch contained in the Ashwagandha root extract was removed by amylase treatment to prepare EA. To evaluate the sleep-promoting activity of EA, a pentobarbital-induced sleep test and electroencephalogram analysis were performed. In addition, the sleep-promoting mechanism of EA was elucidated by analyzing the expression of sleep-related receptors. In …