Digital Commons Network^™

The Effect Of Intermittent Fasting, Caloric Restriction And Exercise On Aging And Longevity: Systematic Review, Romi Hardin

Honors Undergraduate Theses

The purpose of this study was to gain a better understanding of the effects of caloric restriction, intermittent fasting, and exercise on human longevity and aging, and explore their practical applications and inclusions into a healthy lifestyle. By reviewing the existing research and studies, this literature review focuses on identifying and explaining the biological mechanism behind these practices and exploring whether combining practices can be advantageous in extending not only lifespan but health span. The results generally indicate that following either caloric restriction or intermittent fasting and participating in regular exercise have immense results on promoting healthy aging in an …

The Phenomenology Of Place: Rediscovering The Sacred, Renee C. Jones

Honors Undergraduate Theses

The rising prevalence of loneliness and depression, particularly among young adults, has prompted research into the social and environmental factors that influence mental well-being. This thesis examines the relationships between loneliness, symptoms of depression, and dimensions of place attachment—specifically, place identity, place dependence, social bonding, and nature bonding—among UCF students, with subgroup analyses by gender and ethnicity. Additionally, it seeks to incorporate Native American perspectives to explore culturally specific connections to place and community. Due to recruitment challenges, the final sample primarily consists of 201 University of Central Florida students with limited Native American representation.

Quantitative analysis revealed strong positive …

The Role Of Multiteam Systems In Prescribed Fire Operational Incidents, Kevin Llanos

Honors Undergraduate Theses

The purpose of this thesis is to study how multiteam systems (MTS) are implicated in prescribed fire operations and enhance an interdisciplinary understanding of occupational demands in the industry to mitigate worsening environmental challenges. We study publicly accessible sources through a mixed-methods approach applying I/O psychology and discuss relevant literature. Land management plan documentation is reviewed to explore the structural and functional components of prescribed fire teams. We apply theory-driven coding to analyze prescribed fire incident documentation as we study MTS system processes and develop thematic findings. Lastly, industry job listing content and occupational demands are reviewed. Through this archival …

Assessment Of Forensic And Clinical Criteria Of Orbital Blowout Fractures For Use In Bioarchaeological Analysis, Dylan E. Ornot

Honors Undergraduate Theses

Orbital blowout fractures are a particular facial fracture occurring within the inner eye orbits of the face caused by blunt force trauma to the eyeball or the lower orbital rim. This fracture is common in modern clinical contexts due to physical assaults, but examining this fracture in skeletal material can also provide insights into the patterns of interpersonal violence within the fields of bioarchaeology and forensic anthropology. Issues with analyzing this fracture in skeletal material arise due to the clinical assessment practices of blowout fractures, where medical practitioners are highly focused on the soft tissue presentations of the fracture in …

Dysbiosis In Parkinson's Disease: A Meta-Analysis Of Gut Microbiota And Its Role In Gastrointestinal Dysfunction And Disease Progression, Ayan M. Siddiqui Mr.

Honors Undergraduate Theses

Parkinson's Disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor symptoms, including gastrointestinal (GI) dysfunction. Symptoms such as constipation, bloating, and nausea often show early signs before the onset of motor symptoms. Recent research has suggested an essential role of the human gut microbiome and gut dysbiosis, an imbalance in gut microbiota composition, in the pathogenesis of PD. This thesis aims to assess the potential relationship between gut dysbiosis and PD by conducting a meta-analysis, focusing on differences in gut microbiota between PD patients and healthy controls and evaluating their implications for GI dysfunction and PD progression. The …

Examination Of The Morphological Changes And Genotoxic Effects Of Sodium Benzoate On Neuro-2a Cells In Vitro, Emily S. Larson

Honors Undergraduate Theses

Sodium benzoate is a food preservative present in sodas, fruit juices, and other acidic foods and beverages [1]. Its acceptable daily intake is 0-20 mg/kg body weight [2], and it is generally recognized as safe [1, 3]. However, sodium benzoate has been linked to hyperactivity in children [4, 5] and adults [6] and to deficits and behavioral changes in rodents [7-10], indicating potential negative impacts on the nervous system. Sodium benzoate has also induced genotoxic effects in human lymphocytes [11, 12] and Chinese hamster fibroblast cells [13] in vitro and in rat liver tissue in vivo [14]. The effect of …

The Comparative Efficacy Of Ketamine And Esketamine In Treating Anhedonia And Suicidal Ideation: A Meta-Analysis, Yanyi Wu

Honors Undergraduate Theses

This meta-analysis examines the efficacy and effectiveness of racemic ketamine (RS-ketamine) and esketamine in reducing depressive symptoms such as suicidal ideation and anhedonia in patients suffering from treatment-resistant depression and bipolar disorder. This review comprehensively looks at six studies: three clinical studies focusing on suicidal ideation and three looking at anhedonia. Across the studies, RS-ketamine and esketamine were associated with a higher resolution of suicidal ideation, risk, and anhedonia. Significant improvements were noted in the suicidal desire and ideation subscale of the Beck Scale for Suicidal Ideation. The pooled effect size for suicidal ideation (d = 0.533) and pooled …

Synthesizing And Using Iron Oxide Nanoparticles As Nanocomposite In Cotton Fabrics Nanofinishing, Hoda Sharouf, Ziad Saffour

Baghdad Science Journal

Metal oxide nanoparticles, including iron oxide, are highly considered as one of the most important species of nanomaterials in a varied range of applications due to their optical, magnetic, and electrical properties. Iron oxides are common compounds, extensive in nature, and easily synthesized in the laboratory. In this paper, iron oxide nanoparticles were prepared by co-precipitation of (Fe+2) and (Fe+3) ions, using iron (II and III) sulfate as precursor material and NH4OH solution as solvent at 90°C. After the synthesis of iron oxide particles, it was characterized using X-ray diffraction (XRD), infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). These …

A Theoretical Investigation Of Chemical Bonding Of A Heterometallic Trinuclear Cluster Containing Iridium And Ruthenium: [(Cp*Ir) (Cpru)2 (Μ3-H) (Μ-H)3] By Qtaim Approach, Ahlam Hussein Hassan, Muhsen Abood Muhsen Al-Ibadi

Baghdad Science Journal

Numerous integral and local electron density’s topological parameters of significant metal-metal and metal-ligand bonding interactions in a trinuclear tetrahydrido cluster [(Cp* Ir) (Cp Ru)2 (μ3-H) (μ-H)3]1 (Cp = η5 -C5Me5), (Cp* = η5 -C5Me4Et) were calculated and interpreted by using the quantum theory of atoms in molecules (QTAIM). The properties of bond critical points such as the delocalization indices δ (A, B), the electron density ρ(r), the local kinetic energy density G(r), the Laplacian of the electron density ∇2ρ(r), the local energy density H(r), the local potential energy density V(r) and ellipticity ε(r) are compared with data from earlier organometallic …

Genetic Diversity Of Trypanosomes Infesting Cattle From Savannah District In North Of Côte D’Ivoire Using Conserved Genomic Signatures: Rrna, Its1 And Ggapdh, Jean-Yves Ekra, Eliakunda Michael Mafie, Edouard K. N’Goran, Dramane Kaba, Biégo Guillaume Gragnon, Jagan Srinivasan

All Rsif Scholars' Publications

The potential danger to livestock from African animal trypanosomiasis is well known. However, the trypanosome species circulating in cattle and their genetics are poorly understood. After different alignments according to three regions (ITS1, gGAPDH and rRNA gene) of the trypanosome genome, phylogenetic analyses were used to show the genetic diversity of the different species that were circulating in the cattle in three regions (Bagoue, Poro and Tchologo) of Côte d’Ivoire. These analyses were performed by alignment of ITS1; by alignment of partial 18S, ITS1, 5.8S, ITS2 and partial 28S rRNA genes; and by alignment of gGAPDH gene with sequences of …

Empowering Communities Through Education Creating The School Of Green, Kyle Martin

Senior Honors Theses and Projects

The School of Green initiative aims to foster environmental stewardship through community-driven STEM education programs. This paper evaluates the initiative’s impact, critiques its planning, and strategizes for future success. It discusses the evolution of the School of Green Series, its community impact, and future directions. The paper also provides a contextual framework reflective analysis and outlines personal motivations and aspirations. Through meticulous documentation and archival research methods, this project aims to detail the significance of the School of Green Series in promoting environmental education and inclusivity. The comprehensive event report will not only analyze successes and areas for improvement but …

Character Rigging Explorations: Basic Skeleton To Full Simulated Muscle, Lindsay Diana Timbs

Senior Honors Theses and Projects

This thesis project focuses on furthering my knowledge in creating rigs for an organic 3D model with realistic skin deformations. Rigs are the controls used to animate a model. A 3D model's skin deformation is how it squashes and stretches when moved. The project focuses on learning to use simulated muscles, which add the ability to imbue subtle secondary motion to the skin and deliver more realistic deformation as well as the creation of a smooth bind, a standard primary rigging technique. The aim is to compare and contrast their quality based on perceived realism. Subjectively, the muscle simulation was …

The Integration Of Multiple Cardiovascular And Pulmonary Models Into A Single Unified Cardiopulmonary Model, Julian Iii Thrash

Electrical and Computer Engineering

There has been an increasing effort to employ cardiovascular (CV) and pulmonary models to assist in the study of disease, answer research questions, and study the effects of a medical treatment or device. To properly study the intricate dynamics of the CV and pulmonary systems, a comprehensive model is required to achieve a holistic understanding of its mechanics and view the emergent properties of the complex and dynamic cardiopulmonary system. This study builds on the work of Mauro Ursino et al., by taking their multiple CV and pulmonary models and integrating them together within the scalable environment of MATLAB and …

Using Wing Flap Sounds To Distinguish Individual Birds, Thinh Phan

Electrical and Computer Engineering

Ornithologist often need to recognize individual birds, but traditional invasive methods, such as capturing, marking, releasing, and recapturing of birds, have limitations. To overcome this, researchers use non-invasive alternatives, such as bird vocalizations. In our study, we used wing flap sounds of three male Zebra Finch birds for individual recognition. We achieved identification accuracies ranging from 55% to 100% by using a combination of Principal Component Analysis-K-Nearest Neighbor (PCA-KNN) and Cross-Correlation method on training data and testing data. PCA-KNN allows for dimensionality reduction and pattern recognition, while the Cross-Correlation method bases data analysis on shifting data elements. Our approach can …

Effect Of Skin Tone On The Accuracy Of The Estimation Of Arterial Oxygen Saturation By Pulse Oximetry: A Systematic Review, Daniel Martin, Chris Johns, Lexy Sorrell, Eugene Healy, Mandeep Phull, Segun Olusanya, Mark Peters, Jeremy Fabes

Peninsula Medical School

Background: Pulse oximetry-derived oxygen saturation (SpO₂) is an estimate of true arterial oxygen saturation (SaO₂). The aim of this review was to evaluate available evidence determining the effect of skin tone on the ability of pulse oximeters to accurately estimate SaO₂. Methods: Published literature was screened to identify clinical and non-clinical studies enrolling adults and children when SpO₂ was compared with a paired co-oximetry SaO₂ value. We searched literature databases from their inception to March 20, 2023. Risk of bias (RoB) was assessed using the QUADAS-2 tool. Certainty of assessment was evaluated …

Enhancing Mechanical Properties And Water Interactions Of Arabinoxylan Films From Corn Bran Through Enzymatic-Chemical Modification, Abdulrahman Alahmed

Cereal Science

Due to the need to replace non-biodegradable plastics, arabinoxylan (AX) films were evaluated for potential use in food packaging. The mechanical properties, hydrophobicity, and biodegradability of AX films were evaluated after extracting AX from corn bran byproducts of dry-milling (DCB), wet-milling (WCB), and dried distiller’s grains with solubles (DDGS) using acid-alkali procedure. Packaging materials were created using the three AX extracts combined with laccase and sorbitol as the basis for each film. The three AX films were then modified by immersing their surfaces in a lipase-acetate solution. Thickness of modified DCB AX and modified DDGS AX films was significantly increased …

Carotenoids And The Associations With Gut Microbiota Bacterial Populations In Chronic Kidney Disease Hemodialysis Patients, Andrea Kendall

Theses and Dissertations

Background: With increased prevalence and mortality of chronic kidney disease (CKD), treatment by renal replacement therapy using hemodialysis (HD) has increased in parallel. Emerging evidence suggests that gut microbiota play an important role in the progression of CKD; influential dietary factors have not been studied exhaustively to date.

Objective: To explore the relationships between dietary carotenoid intake, the abundance of specific gut microbiota, and symptom-related outcomes in patients with CKD on HD.

Methods: This cross-sectional study investigated the gut microbiota characteristics relative to carotenoid intake in CKD subjects on HD in central Illinois (n = 20). The Block Dialysis …

A Bioarchaeological Overview Of The Late Woodland Period Gooden Mound Group, Fulton County, Illinois, Aaron M. Durchholz

Theses and Dissertations

Extensive research in paleopathology has documented adverse effects accompanying a shift in subsistence strategy from largely nomadic, hunting and gathering lifestyles to those of more sedentary, agrarian systems. Comparative assessment of the human skeletal remains of early foragers and later farmers recovered from archaeological sites around the world have consistently demonstrated a decrease in average age at death in the latter.

Across the pre-Columbian North American Midwest, the transitional period between the Late Woodland and Mississippian periods, sometimes referred to as the terminal or Mississippian Acculturated Late Woodland, portended establishment of semi-permanent to permanent hamlets, increasingly reliant upon the adoption …

Decoding Tofu Quality: An Integrative Investigation Of Soybean Seed Characteristics And Innovative Evaluation Approaches, Amanda Malik

Cereal Science

This research unravels the intricate relationship between soybean seed characteristics, geographical origin, and the resultant quality parameters of tofu. The study analyzed 178 soybean varieties from diverse regions, categorizing them into distinct clusters based on protein, moisture, and other attributes. Significant variations emerged, with soybeans from the United States exhibiting higher protein, while Chinese sources displayed higher moisture content. Subsequently, the research delved into diverse tofu quality parameters using multivariate analysis. Distinct clusters were identified based on attributes including yield, texture, moisture content, and brix levels. These parameters exhibited complex interrelationships, providing insights into factors defining tofu sensory qualities. Furthermore, …

Ketogenic Diet In Treating Sepsis-Related Acquired Weakness: Is It Friend Or Foe?, Yanmei Miao, Leiyu Xie, Shaolin Chen, Xiaoming Zhang, Wenjie Liu, Peng Xie

Faculty, Staff and Students Publications

Background: Sepsis is the body's extreme response to an infection leading to organ dysfunction. Sepsis-related acquired weakness (SAW), a critical illness closely related to metabolic disorders, is characterized by generalized sepsis-induced skeletal muscle weakness, mainly manifesting as symmetrical atrophy of respiratory and limb muscles. Muscle accounts for 40% of the body's total mass and is one of the major sites of glucose and energy absorption. Diet affects skeletal muscle metabolism, which further impacts physiology and signaling pathways. The ketogenic diet (KD) is a high-fat, low-carbohydrate diet that has shown benefits in patients with a variety of neuromuscular disorders. Patients with …

Liver Directed Adeno-Associated Viral Vectors To Treat Metabolic Disease, Marcel A Chuecos, William R Lagor

Faculty, Staff and Students Publications

The liver is the metabolic center of the body and an ideal target for gene therapy of inherited metabolic disorders (IMDs). Adeno-associated viral (AAV) vectors can deliver transgenes to the liver with high efficiency and specificity and a favorable safety profile. Recombinant AAV vectors contain only the transgene cassette, and their payload is converted to non-integrating circular double-stranded DNA episomes, which can provide stable expression from months to years. Insights from cellular studies and preclinical animal models have provided valuable information about AAV capsid serotypes with a high liver tropism. These vectors have been applied successfully in the clinic, particularly …

The Impact Of Obesity-Associated Glycine Deficiency On The Elimination Of Endogenous And Exogenous Metabolites Via The Glycine Conjugation Pathway, Hong Chang Tan, Jean W Hsu, E Shyong Tai, Shaji Chacko, Jean-Paul Kovalik, Farook Jahoor

Faculty, Staff and Students Publications

BACKGROUND: Glycine is an integral component of the human detoxification system as it reacts with potentially toxic exogenous and endogenously produced compounds and metabolites via the glycine conjugation pathway for urinary excretion. Because individuals with obesity have reduced glycine availability, this detoxification pathway may be compromised. However, it should be restored after bariatric surgery because of increased glycine production.

OBJECTIVE: To examine the impact of obesity-associated glycine deficiency on the glycine conjugation pathway. We hypothesize that the synthesis rates of acylglycines from endogenous and exogenous sources are significantly reduced in individuals with obesity but increase after bariatric surgery.

METHODS: We …

Choice Of Adjuvant And Antigen Composition Alters The Immunogenic Profile Of A Sars-Cov-2 Subunit Vaccine, William R Lykins, Jeroen Pollet, Jessica A White, Brian Keegan, Leroy Versteeg, Ulrich Strych, Wen-Hsiang Chen, Raodoh Mohamath, Gabi Ramer-Denisoff, Sierra Reed, Samuel Beaver, Alana Gerhardt, Emily A Voigt, Mark A Tomai, Robert Sitrin, Robert K M Choy, Frederick J Cassels, Peter J Hotez, Maria Elena Bottazzi, Christopher B Fox

Faculty, Staff and Students Publications

Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations. Optimizing the immune response's quality, amplitude, and durability to these vaccines depends on the appropriate adjuvant choice and dose in combination with the selected antigen.

Methods: Here, we employed a preclinical mouse model to study the adaptive humoral and cellular immune responses to a SARS-CoV-2 receptor binding domain (RBD) antigen formulated with one of four different immune agonists [GLA, 3M-052, CpG-1826 (CpG), and dmLT], in combination with one of two different immune-stimulating formulations, a stabilized squalene emulsion (SE) or aluminum hydroxide …

Heat-Treated Soybean Meal In Beef Cattle Diets, Grady Gullickson

Animal Sciences

Two experiments were conducted to evaluate replacing dried distillers grains with solubles (DDGS) with heat-treated soybean (TSBM) at increasing rates in forage-based diets on steer growth performance, nutrient flow, and digestibility. Experiment 1: 70 angus-based steers were utilized in a generalized randomized block design for an 85-d growing study at the NDSU Beef Cattle Research Complex. Experiment 2: five fistulated Jersey steers fitted with ruminal, duodenal, and ileal cannulas were utilized in a 4 × 5 row column design for 56 d to measure nutrient flow and digestibility. Diets were formulated to replace DDGS, included in the diet at 16% …

The Impact Of Media On Price Paid For Thoroughbred Horses At Auction, Steven Anderson

Animal Sciences

It has been said a picture is worth a thousand words, but the economic value of that picture for livestock sales transactions has not been quantified. The objective of this study aimed to evaluate the effect of the presence of media (photos and/or video) on sale prices of Thoroughbreds. Online auction sale data from two U.S. Thoroughbred auction sites were used to compare 18,221 horses that sold and 4,215 horses that failed to meet the minimum desired bid. Sellers that provided media of their horses at auction received approximately $25,000 more for weanlings, $74,000 more for yearlings, and $89,500 more …

One-Carbon Metabolites, Fetal Growth, Maternal Oxidative Stress, And Fetal Programming During Early Gestation, Layla King

Animal Sciences

In ruminant production systems, maternal nutrient intake and supplementation practices vary widely throughout the industry. Adequate maternal nutrient supply is critical for fetal development and subsequent offspring performance and health. Therefore, determining strategic supplementation of specific nutrients during critical developmental windows is crucial to fetal growth during early gestation will positively impact beef cattle production systems. In this dissertation, two experiments using beef heifers were conducted to test the hypothesis that differing maternal rate of gain (achieved through differing intake) during the first 63 d of pregnancy would compromise indices of maternal and fetal development; and that strategic nutrient supplementation …

Gendered Violence And Sexualized Representations In Video Games: (Lack Of) Effect On Gender-Related Attitudes, Liam Cross, Linda K. Kaye, Juris Savostijanovs, Neil Mclatchie, Matthew Johnston, Liam Whiteman, Robyn Mooney, Gray Atherton

School of Psychology

This research explored how gender portrayals in video games affect gender-related attitudes. Two hundred participants from the United Kingdom and Malaysia participated across three experiments, where the appearance and behaviour of video game characters were manipulated with regard to target (enemy) gender (Study 1), sexually explicit attire (Study 2) and level of character agency (Study 3). We found minimal evidence that exposure to gender-stereotyped content resulted in differential gender-related attitudes (implicit associations, hostile and benevolent sexism, or rape myth acceptance). However, Study 1 findings showed that individuals who played a first-person shooter with male enemies showed lower endorsement of some …

Reward Count(S): Negative Recency In Probabilistic Experience-Based Learning, Andy Wills, René Schlegelmilch, Bettina Von Helversen

School of Psychology

Learning how to make decisions from experience is often studied using probabilistic outcome prediction or choice tasks, asin conditioning, reward learning, or risky gambles (e.g., response A provides reward in 75% of the cases, response B in25% over repeated trials with feedback). One debated phenomenon in such tasks is that of negative recency, describingthat learners expect the rare event after observing a streak ofcommon events (e.g., Gamblers fallacy). Here, we show thatthis behavior, despite instructing participants to use a visualstimulus, also occurs in probabilistic single-cue conditioningtraining, where participants predicted whether digging at a specific location on a plane (visual cue) …

“We’Ve All Come Together”: A Board Game Intervention For Children And Adults With Autism And Other Developmental Disabilities, Gray Atherton, Emily Dawson, Liam Cross

School of Psychology

The authors discuss how board games offer individuals with autism (whooften struggle with social settings and require structured outlets for building relationships) an affordable, naturalistic, collaborative environmentthat is stimulating, engaging, and educational. Board games, they assert,provide opportunities to practice social skills, including cooperation andsocial deduction, essential skills for both neurotypical and atypical people.The authors include recommendations for introducing board games intospecial educational settings. K

Everyday Places To Get Away – Lessons Learned From Covid-19 Lockdowns, B. Gatersleben, Emma V. White, K.J. Wyles, S.E. Golding, G. Murrell, C. Scarles, T. Xu, B.F.T. Brockett, C. Willis

School of Psychology

Being able to get away from everyday stressors and demands, even if close to home and just for a few minutes, is important for wellbeing. During the Covid-19 lockdown periods, people's ability to get away changed significantly. An increase in visits to nearby natural places is well documented. Little is known about other types of places people visited to get away. An online UK survey was conducted in 2020 (N = 850) investigating what places people visited to get away during the pandemic, what they did in those places, how place and activity choices were related to each other and …