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Pepperdine Journal Of Communication Research 2024, Morgan Purdy

Pepperdine Journal of Communication Research

No abstract provided.

Factors Predicting The Intention To Engage In Self-Protective Behavior Against Monkeypox Infection Among Thai People, Awirut Singkun, Wichan Phibarn, Wichaporn Intharachuti, Arunothai Derramon, Thitika Kimise

Journal of Health Research

Background: An emerging monkeypox outbreak in many countries caused the WHO to declare the disease an international public health problem. This study aimed to explore knowledge of monkeypox and its transmission, intention to engage in self-protection, and factors predicting the intention to engage in self-protective behavior among Thai people.

Methods: A cross-sectional design was conducted between September and October 2022 with a self-administered questionnaire through an online survey. A total of 581 respondents were included in the data analysis. Descriptive statistics, and a binary logistic regression were used.

Results: Most respondents had good knowledge of monkeypox and its transmission …

Full Issue, Meadowlark

Meadowlark

No abstract provided.

Epck Transfer Between Math And Science, Elise Marie Joyner

Theses and Dissertations

Generalist elementary school teachers have little time to develop enacted pedagogical content knowledge (ePCK) in all content areas. Therefore, the transfer of ePCK from one content area to another, such as between math and science, can help generalist teachers build their knowledge needed for teaching regardless of their content area strengths. This self-study examines the ePCK components and their elements present in both math and science instruction. I am a fifth-grade teacher in Utah County who has been teaching for 4 years. Math is taught daily, and science is taught approximately three times a week. The self-study includes six video …

Kratom Safety And Toxicology In The Public Health Context: Research Needs To Better Inform Regulation, Jack E. Henningfield, Oliver Grundmann, Marilyn A. Huestis, Kirsten E. Smith

Institute of Emerging Health Professions Faculty Papers

Although kratom use has been part of life for centuries in Southeast Asia, the availability and use of kratom in the United States (US) increased substantially since the early 2000s when there was little information on kratom pharmacology, use patterns, and effects, all critical to guiding regulation and policy. Here we provide a synthesis of research with several hundred English-language papers published in the past 5 years drawing from basic research, epidemiological and surveillance data, and recent clinical research. This review of available literature aims to provide an integrated update regarding our current understanding of kratom's benefits, risks, pharmacology, and …

Revolutionize Your Child's Future With The Ultimate Smart Education System, Sam Smith

Student Works

In the journey of life, education is the compass that guides our children toward a brighter future. Yet, in today's fast-paced digital world, the traditional compass is evolving into a sophisticated GPS. Enter the Smart Education System—a revolutionary beacon that harnesses the power of technology to illuminate personalized, engaging, and effective learning pathways. This guide delves into how the ultimate Smart Education System can transform your child's future, paving the way to endless possibilities.

Race, Religion, And Reconciliation: Building A Mosaic Of Latine Faith From The Margins, Sabrina A. Ochoa

University of Miami Race & Social Justice Law Review

No abstract provided.

Are Healthy Foods “White People Food”: A Legal Analysis Of Disparities In Healthy Food Accessibility And Affordability At Grocery Stores And Restaurants In Low-Income Neighborhoods, Sara St. Juste

University of Miami Race & Social Justice Law Review

No abstract provided.

Democracy, Chevron Deference, And Major Questions Anti-Deference, Richard W. Murphy

Georgia Law Review

In 1984, the Supreme Court in its Chevron opinion invoked democratic values to help justify holding that courts should defer to an agency’s reasonable construction of a statute that it administers. In 2022, in West Virginia v. EPA, the Court invoked democratic values to help justify the major questions doctrine (MQD), which requires clear congressional authorization for agency claims of major regulatory power. Democracy, it seems, requires deference and anti-deference for agency statutory interpretations.

Or maybe not. This Article submits that the democracy talk of Chevron and West Virginia is implausible, misleading, and may have caused the law to evolve …

Can The Automated State Be Trusted? The Role Of Rule Of Law Safeguards For Governing Automated Decision-Making And Artificial Intelligence, Joanna Mazur, Maciej Bernatt

Georgia Law Review

The goal of this Article is to take a broader perspective on the lessons which can be learned from the implementation of automated decision-making in the public sector—specifically in regard to how procedural rule of law mechanisms can make such projects trustworthy. The underlying idea behind this Article is to posit the debate about the ADM within the context of rule of law as a key notion in liberal democracies. At the same time, we rely on a law and political economy framework. We look through the lens of power relations and assess to what extent selected procedural solutions governing …

El Zacahuil: Lo Que Encubre Y Lo Que Se Quiere Ver, Ana Bella Pérez Castro

Maya America: Journal of Essays, Commentary, and Analysis

Resumen: En este texto presento la importancia que cobra un gran tamal, conocido como zacahuil, bolin, tapataxtle, tlapepecholi o patlache en diversos rituales que se realizan en la Huasteca. Parto de mostrar al lector la ubicación de esta extensa región conocida como la Huasteca y la manera en que en ella encontramos la presencia de los teenek, grupo étnico de filiación maya, que ahí se asentaron interactuando con los nahuas y otomíes principalmente. La importancia que cobra también en Yucatán el mukbil pollo o pibil pollo me llevaría a suponer que fueron los teenek los que llevaron, en su equipaje …

Los Tamales De La Gente Del Pantano. Patrimonio Gastronómico De Los Yokot’Anob De Tabasco, México, Mauricio Hernández Sánchez

Maya America: Journal of Essays, Commentary, and Analysis

Resumen: Los tamales forman parte de la cotidianidad de los yokot’anob, un pueblo de filiación mayense que habita las planicies inundables de Tabasco, en el sureste mexicano. Constituyen las principales ofrendas de las festividades religiosas y de los rituales asociados a la muerte y a diversas entidades sagradas del monte, el agua y las cosechas. Además, están presentes en reuniones familiares, festivales escolares y, en general, en todo convivio que incluya alimentos. Sin embargo, poca de esta gastronomía local se conoce. El presente ensayo describe parte de la diversidad de tamales yokot’anob, entre los que se listan los de “presa”, …

She’S Got Her Ticket: The Lived Experience Of Reimagined Identity Among University-Educated Caribbean Black Gay Women, Sa-Rawla Stoute

Theses and Dissertations

The voice of Black gay women in the Anglophone Caribbean is often missing from the literature. This phenomenological study focuses on the lived experience of reimagined identity among university-educated Black gay women in the Anglophone Caribbean. This study also examines their meaning-making and agentive practices as they navigate cultural artifacts and negotiate their identity. Using van Manen’s data collection methods and analysis, this study highlights essential themes around a reimagined identity: reimagining requires permission, and reimagining one’s identity transforms frames of reference. Findings also highlight how participants use space and control their environment as resistance strategies and how they made …

Influence Of Steroidal Implants And Zinc Sulfate Supplementation On Growth Performance, Trace Mineral Status, Circulating Metabolites, And Transcriptional Changes In Skeletal Muscle Of Feedlot Steers, Dathan T. Smerchek, Emma L. Rients, Amy M. Mclaughlin, Kara J. Thornton, Stephanie L. Hansen

Animal, Dairy, and Veterinary Science Faculty Publications

Angus-cross steers (n = 144; 362 kg ± 20.4) were used to determine the effect of Zn and steroidal implants on performance, trace mineral status, circulating metabolites, and transcriptional changes occurring in skeletal muscle. Steers (n = 6 per pen) were stratified by body weight (BW) in a 3 x 2 factorial. GrowSafe bunks recorded individual feed intake (steer as experimental unit; n = 24 per treatment). Dietary treatments (ZINC; eight pens per treatment) included supplemental Zn as ZnSO₄ at 1) 0 (analyzed 54 mg Zn/kg DM; Zn0); 2) 30 mg/kg DM ( …

An Assessment Of Equity, Compounding Disasters, And Climate Change In Hazard Mitigation Planning For The Portland Metro Region, Chris Lower

Geography Masters Research Papers

Hazard mitigation plans (HMPs) are strategic documents or policies developed by governments, communities, and organizations to identify risks and reduce the impacts of natural and human- made hazards. These plans aim to minimize loss of life, property damage, and disruption from floods, wildfires, snowstorms, heatwaves, and other disasters. While useful, these plans infrequently and unevenly address the lived experiences of marginalized populations who bear the disproportionate impacts of recurrent disasters. Technocratic planning goals exacerbate these impacts by failing to center inclusive and equity-focused approaches, thus eroding the resilience capacities of many vulnerable groups including the poor and communities of color. …

Riluzole For Degenerative Cervical Myelopathy: A Secondary Analysis Of The Csm-Protect Trial, Michael G. Fehlings, Karlo M. Pedro, Mohammed Ali Alvi, Jetan H. Badhiwala, Henry Ahn, H. Francis Farhadi, Christopher I. Shaffrey, Ahmad Nassr, Praveen Mummaneni, Paul M. Arnold, W. Bradley Jacobs, K. Daniel Riew, Michael Kelly, Darrel S. Brodke, Alex Vaccaro, Alan Hilibrand, Jason Wilson, James Harrop, S. Tim Yoon, Kee D. Kim, Daryl R. Fourney, Carlo Santaguida, Eric M. Massicotte, Peng Huang

Department of Orthopaedic Surgery Faculty Papers

IMPORTANCE: The modified Japanese Orthopaedic Association (mJOA) scale is the most common scale used to represent outcomes of degenerative cervical myelopathy (DCM); however, it lacks consideration for neck pain scores and neglects the multidimensional aspect of recovery after surgery.

OBJECTIVE: To use a global statistical approach that incorporates assessments of multiple outcomes to reassess the efficacy of riluzole in patients undergoing spinal surgery for DCM.

DESIGN, SETTING, AND PARTICIPANTS: This was a secondary analysis of prespecified secondary end points within the Efficacy of Riluzole in Surgical Treatment for Cervical Spondylotic Myelopathy (CSM-PROTECT) trial, a multicenter, double-blind, phase 3 randomized clinical …

Noninvasive Technique For Measuring Cardiac Output, Grace E. Kolar, Rachel Simonton, Eli Strohecker

Williams Honors College, Honors Research Projects

NA

Single-Molecule Orientation Imaging Reveals The Nano-Architecture Of Amyloid Fibrils Undergoing Growth And Decay, Brian Sun, Tianben Ding, Weiyan Zhou, Tara S. Porter, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Amyloid-beta (Aβ42) aggregates are characteristic Alzheimer’s disease signatures, but probing how their nanoscale architectures influence their growth and decay remains challenging using current technologies. Here, we apply time-lapse single-molecule orientation-localization microscopy (SMOLM) to measure the orientations and rotational “wobble” of Nile blue (NB) molecules transiently binding to Aβ42 fibrils. We correlate fibril architectures measured by SMOLM with their growth and decay over the course of 5 to 20 min visualized by single-molecule localization microscopy (SMLM). We discover that stable Aβ42 fibrils tend to be well-ordered and signified by well-aligned NB orientations and small wobble. SMOLM also shows that increasing order …

Tree Rings Reveal The Transient Risk Of Extinction Hidden Inside Climate Envelope Forecasts, Margaret E. K. Evans, Sharmila M. N. Dey, Kelly A. Heilman, John R. Tipton, R. Justin Derose, Stefan Klesse, Emily L. Schultz, John D. Shaw

Wildland Resources Faculty Publications

Given the importance of climate in shaping species' geographic distributions, climate change poses an existential threat to biodiversity. Climate envelope modeling, the predominant approach used to quantify this threat, presumes that individuals in populations respond to climate variability and change according to species-level responses inferred from spatial occurrence data—such that individuals at the cool edge of a species' distribution should benefit from warming (the "leading edge"), whereas individuals at the warm edge should suffer (the "trailing edge"). Using 1,558 tree-ring time series of an aridland pine (Pinus edulis) collected at 977 locations across the species' distribution, we found …

Star Power: An Analysis Of Digital Astrology Content As An Instrument Of Political Tractability, Aliza Phillips

Comparative Literature M.A. Essays

In an essay from 1953 titled, The Stars Down to Earth, Theodor Adorno performed an exacting analysis of the weekly horoscopes published in The Los Angeles Times to illuminate the latent authoritarianism embedded in the rhetoric of astrology. One of Adorno’s primary arguments is that an insidious form of political tractability is forged through the simultaneous determinism and individualism of astrology. Seventy years after The Stars Down to Earth, the genre of short-form astrology videos has skyrocketed in popularity across social media platforms. This essay offers a series of close readings of digital astrology videos to theorize both …

Targeting Cancers With Ohsv-Based Oncolytic Viral Immunotherapy, Rakin Tammam Nasar, Ifeanyi Kingsley Uche, Konstantin G. Kousoulas

School of Medicine Faculty Publications

The recent success of cancer immunotherapies, such as immune checkpoint inhibitor (ICIs), monoclonal antibodies (mAbs), cancer vaccines, and adoptive cellular therapies (ACTs), has revolutionized traditional cancer treatment. However, these immunotherapeutic modalities have variable efficacies, and many of them exhibit adverse effects. Oncolytic viral Immunotherapy (OViT), whereby viruses are used to directly or indirectly induce anti-cancer immune responses, is emerging as a novel immunotherapy for treating patients with different types of cancer. The herpes simplex virus type-1 (HSV-1) possesses many characteristics that inform its use as an effective OViT agents and remains a leading candidate. Its recent clinical success resulted in …

Un Recorrido Iconoglífico Por Las Antiguas Representaciones Del Tamal En La Mesoamérica Maya De Tierras Bajas, Daniel Martínez González

Maya America: Journal of Essays, Commentary, and Analysis

Resumen: En el presente texto se ofrece un recorrido histórico milenario por las representaciones, tanto visuales o iconográficas, como epigráficas o escriturarias, de uno de los alimentos -al parecer- más antiguos, preciados y generalizados entre los pueblos mayas desde épocas tempranas. Como tal, la hoja de ruta de este recorrido en torno a las representaciones del tamal en el mundo maya -de sobre todo Tierras Bajas- inicia por las célebres pinturas murales del sitio de San Bartolo (ca. s. i a.e.c) y la subestructura I-4 de Chiik Nahb de Calakmul (ca. 650-700 e.c.); prosigue con algunos otros indicadores arqueológicos y …

Klrg1 Cell Depletion As A Novel Therapeutic Strategy In Patients With Mature T-Cell Lymphoma Subtypes, Bimarzhan Assatova, Robert Willim, Christopher Trevisani, Garrett Haskett, Khyati Maulik Kariya, Kusha Chopra, Sung Rye Park, Michael Yevgeniy Tolstorukov, Sean M Mccabe, Jessica Duffy, Abner Louissaint, Jani Huuhtanen, Dipabarna Bhattacharya, Satu Mustjoki, Min Jung Koh, Foster Powers, Elizabeth A Morgan, Lei Yang, Brandy Pinckney, Matthew J Cotton, Andrew Crabbe, Jessica Beth Ziemba, Ian Brain, Tayla B Heavican-Foral, Javeed Iqbal, Ronald Nemec, Anna Baird Rider, Josie Germain Ford, Min Ji Koh, Nora Scanlan, David J Feith, Thomas P Loughran, Won Seog Kim, Jaehyuk Choi, Juliette Roels, Lena Boehme, Tom Putteman, Tom Taghon, Jeffrey A Barnes, P Connor Johnson, Eric D Jacobsen, Steven A Greenberg, David M Weinstock, Salvia Jain

Faculty, Staff and Student Publications

Purpose: Develop a novel therapeutic strategy for patients with subtypes of mature T-cell and NK-cell neoplasms.

Experimental design: Primary specimens, cell lines, patient-derived xenograft models, commercially available, and proprietary anti-KLRG1 antibodies were used for screening, target, and functional validation.

Results: Here we demonstrate that surface KLRG1 is highly expressed on tumor cells in subsets of patients with extranodal NK/T-cell lymphoma (ENKTCL), T-prolymphocytic leukemia (T-PLL), and gamma/delta T-cell lymphoma (G/D TCL). The majority of the CD8+/CD57+ or CD3-/CD56+ leukemic cells derived from patients with T- and NK-large granular lymphocytic leukemia (T-LGLL and NK-LGLL), respectively, expressed surface KLRG1. The humanized afucosylated anti-KLRG1 …

A Randomized Double Blind Placebo Controlled Trial To Assess The Safety And Efficacy Of A Patented Fenugreek (Trigonella Foenum-Graecum) Seed Extract In Type 2 Diabetics, Rajinder Singh Gupta, Amarjit Singh Grover, Pawan Kumar, Apurva Goel, Samudra P. Banik, Sanjoy Chakraborty, Mehul Rungta, Manashi Bagchi, Partha Pal, Debasis Bagchi

Publications and Research

Background: Fenugreek plant (Trigonella foenum-graecum) constitutes a traditionally acclaimed herbal remedy for many human ailments including diabetes, obesity, neurodegenerative diseases, and reproductive disorders. It is also used as an effective anti-oxidative, anti-inflammatory, antibacterial, and anti-fungal agent. The seed of the plant is especially enriched in several bioactive molecules including polyphenols, saponins, alkaloids, and flavonoids and has demonstrated potential to act as an antidiabetic phytotherapeutic. A novel patented formulation (Fenfuro^®) was developed in our laboratory from the fenugreek seeds which contained >45% furostanolic saponins (HPLC).

Objective: A placebo-controlled clinical compliance study was designed to assess …

Irx4204 Induces Senescence And Cell Death In Her2-Positive Breast Cancer And Synergizes With Anti-Her2 Therapy, Cassandra L Moyer, Amanda Lanier, Jing Qian, Darian Coleman, Jamal Hill, Vidyasagar Vuligonda, Martin E Sanders, Abhijit Mazumdar, Powel H Brown

Faculty, Staff and Student Publications

PURPOSE: Rexinoids, agonists of nuclear retinoid X receptor (RXR), have been used for the treatment of cancers and are well tolerated in both animals and humans. However, the usefulness of rexinoids in treatment of breast cancer remains unknown. This study examines the efficacy of IRX4204, a highly specific rexinoid, in breast cancer cell lines and preclinical models to identify a biomarker for response and potential mechanism of action.

EXPERIMENTAL DESIGN: IRX4204 effects on breast cancer cell growth and viability were determined using cell lines, syngeneic mouse models, and primary patient-derived xenograft (PDX) tumors. In vitro assays of cell cycle, apoptosis, …

Early Threads Of Connection. Probing Infants' Understanding Of Caregiving Relationships, Christina Steele, Megan Richardson, Denis Tatone, Ashley Thomas

School of Psychology

Despite the centrality of caregiving relationships in the lives of infants, little is known about whether and how infants represent these relationships characterized by strong attachment and asymmetry in obligation and skills. The current studies (N=95) investigate whether 8-to-10-month-old infants attend to two cues‚Äîaffiliative touch and physical size‚Äîto predict who will respond to distress. In Study 1 (n=49), infants expected larger characters to respond to the emotional needs of smaller characters, only when they saw affiliative touch (proportion looking time at large character: BF10=6.72). In Study 2 (n=46), they did not expect smaller characters to respond to larger characters (proportion …

Infants Expect An Agent To Choose A Goal That Can Be Reached At A Lower Cost, Laura Schingloff-Nemecz, Denis Tatone, Barbara Pomiechowska, Gergely Csibra

School of Psychology

According to prominent accounts of early actionunderstanding, infants’ interpretation of others’ actions isundergirded by an assumption of utility maximization.However, it is unclear whether this assumption applies only toselection among actions or also to selection among goals. Here,using an eye-tracking paradigm, we investigated whether 14-to 16-month-old infants would predict an agent to choose alower-cost option when faced with two identical outcomes thatcould be reached at different costs. Infants directed more looksto the lower-cost option, and this effect was not merely due tovisual saliency. These findings corroborate the proposal thatinfants rely on utility maximization when reasoning about anagent’s likely goal and provide …

Ford Madox Ford’S Unusual War: Ongoing Worry And Modernity, Nur Karatas

English: Faculty Publications and Other Works

In Parade’s End, Ford Madox Ford approaches the experience of trauma in an unusual way—it is no longer just past experiences, but the expectancy of dismal events that become as traumatic. Ford chooses worry for such rendering. In order to make the correlation between suffering and sensibility, he places worry in the lives of his characters, which reflects on Ford’s own life. This discussion will introduce the idea that worry is going to be a major component of Ford’s psychologising of war. I explore this worry-driven sensibility and the ways it is reflected, especially in the characters’ obsession with the …

Telomere Dysfunction Alters Intestinal Stem Cell Dynamics To Promote Cancer, Kyle A Labella, Wen-Hao Hsu, Jiexi Li, Yutao Qi, Yonghong Liu, Jingjing Liu, Chia-Chin Wu, Yang Liu, Zingzhi Song, Yiyun Lin, Jonathan M Blecher, Shan Jiang, Xiaoying Shang, Jincheng Han, Denise J Spring, Jianhua Zhang, Yan Xia, Ronald A Depinho

Faculty, Staff and Student Publications

Telomere dynamics are linked to aging hallmarks, and age-associated telomere loss fuels the development of epithelial cancers. In Apc-mutant mice, the onset of DNA damage associated with telomere dysfunction has been shown to accelerate adenoma initiation via unknown mechanisms. Here, we observed that Apc-mutant mice engineered to experience telomere dysfunction show accelerated adenoma formation resulting from augmented cell competition and clonal expansion. Mechanistically, telomere dysfunction induces the repression of EZH2, resulting in the derepression of Wnt antagonists, which causes the differentiation of adjacent stem cells and a relative growth advantage to Apc-deficient telomere dysfunctional cells. Correspondingly, in this mouse model, …

Responsible Artificial Intelligence For Climate Action: A Theoretical Framework For Sustainable Development, Byeong-Gwon Kang, Yunyoung Nam

Sustainable Machine Intelligence Journal

Climate change poses an urgent and significant challenge, with far-reaching impacts already affecting our planet, and projections indicating worsening conditions in the future. The concept of sustainable development aims to meet present needs while safeguarding the ability of future generations to meet their own requirements. However, climate change's effects on sustainable development are of paramount concern, as they amplify issues like poverty, food insecurity, and environmental degradation, affecting economic growth, social progress, and environmental protection. Taking immediate action to mitigate climate change and implement sustainable practices is crucial to ensuring a habitable planet for future generations. In this context, Responsible …