Faculty Spotlight: Bonnie Brown, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Neuroinflammation And Gut Barrier Function Post Traumatic Brain Injury, Anne Sullivan

Master's Theses

Traumatic Brain Injury (TBI) is a major cause of morbidity and mortality that afflicts millions of people in the United States annually. TBI mice had significantly increased expression of the pro-inflammatory cytokines and decreased expression of tight junction proteins CLDN5, CLDN12, and OCLD in brain lesion tissue. TBI mice exhibited a significant accumulation of FITC in the middle and distal part of the small intestine compared to sham mice. TBI mice exhibited an increase in pathogenic bacteria Enterobacteriaceae and a decrease in beneficial bacteria lactobacillus. TBI mice exhibited a trend toward an increase in permeability compared to no treatment. These …

Identification And Characterization Of Cannabichromene's Major Metabolite Following Incubation With Human Liver Microsomes, Alexandra M Ward, Touraj Shokati, Jost Klawitter, Jelena Klawitter, Vu Nguyen, Laura Kozell, Atheir I Abbas, David Jones, Uwe Christians

Faculty, Staff and Student Publications

Cannabichromene (CBC) is a minor cannabinoid within the array of over 120 cannabinoids identified in the Cannabis sativa plant. While CBC does not comprise a significant portion of whole plant material, it is available to the public in a purified and highly concentrated form. As minor cannabinoids become more popular due to their potential therapeutic properties, it becomes crucial to elucidate their metabolism in humans. Therefore, the goal of this was study to identify the major CBC phase I-oxidized metabolite generated in vitro following incubation with human liver microsomes. The novel metabolite structure was identified as 2′-hydroxycannabicitran using gas chromatography–mass …

Fleeing Towards Healing: How Cam Can Heal Refugee Communities, Sarah B. Shaalan

Master's Theses

Alternative methods of healing can be found across the globe and are used by all kinds of people including refugees. This thesis will explore the potential benefits of Complementary and Alternative Medicine otherwise known as “CAM” as a supplementary strategy for helping refugees to deal with stress, Post Traumatic Stress Disorder (PTSD) and other harmful effects sustained on their journey and lives as displaced peoples. I will do so by first situating my project in the literature on Eurocentrism in healing practices and the emergence of CAM as an alternative. Then, using extensive primary and secondary sources, supplemented by an …

Serum Lipoproteins Are Associated With Coronary Atherosclerosis In Asymptomatic U.S. Adults Without Traditional Risk Factors, Ricardo Cury, Theodore Feldman, Jonathan Fialkow, Khurram Nasir

All Publications

Background: The relationship between atherogenic lipoproteins and subclinical coronary atherosclerosis has not been thoroughly evaluated in low-risk adults.

Objectives: The purpose of this study was to assess the association of low-density lipoprotein cholesterol (LDL-C), non-high-density lipoprotein cholesterol (HDL-C), and apolipoprotein B (apoB) with coronary atherosclerosis in adults without traditional risk factors.

Methods: We assessed atherosclerosis on coronary computed tomography angiography among asymptomatic adults in the Miami Heart Study not taking lipid-lowering therapy and without hypertension, diabetes, or active tobacco use. Prevalence of atherosclerosis was evaluated based on serum LDL-C, non-HDL-C, and apoB, and multivariable logistic regression with forward selection was …

Biological Lags And Market Dynamics In Vertically Coordinated Food Supply Chains: Hpai Impacts On U.S. Egg Prices, James L. Mitchell, Jada M. Thompson, Trey Malone

Department of Agricultural Economics Faculty Publications

It is well known that livestock production involves long biological lags. Failure to account for these biological lags can result in the misspecification of supply chain relationships and adjustments to market shocks, which can have significant implications for policy decisions. An example is the 2022 Highly Pathogenic Avian Influenza (HPAI) event that caused high mortality rates in domestic poultry supply chains and reduced egg production. We use the 2022–2023 HPAI event to highlight the implications of misspecification of disease dynamics in agri-food systems. Specifically, we examine the impact of HPAI on U.S. egg prices in 2022–2023. To do this, we …

Chagas Disease In Immunocompromised Patients, Eva H Clark, Louisa A Messenger, Jeffrey D Whitman, Caryn Bern

Faculty, Staff and Students Publications

As Chagas disease remains prevalent in the Americas, it is important that healthcare professionals and researchers are aware of the screening, diagnosis, monitoring, and treatment recommendations for the populations of patients they care for and study. Management of Trypanosoma cruzi infection in immunocompromised hosts is challenging, particularly because, regardless of antitrypanosomal treatment status, immunocompromised patients with Chagas disease are at risk for T. cruzi reactivation, which can be lethal. Evidence-based practices to prevent and manage T. cruzi reactivation vary depending on the type of immunocompromise. Here, we review available data describing Chagas disease epidemiology, testing, and management practices for various …

Comorbid Neurotrauma Increases Neurodegenerative-Relevant Cognitive, Motor, And Autonomic Dysfunction In Patients With Rapid Eye Movement Sleep Behavior Disorder: A Substudy Of The North American Prodromal Synucleinopathy Consortium, Jonathan E Elliott, Jennifer Mcleland, Yo-El S Ju, Et Al.

2020-Current year OA Pubs

STUDY OBJECTIVES: Rapid eye movement sleep behavior disorder (RBD) is strongly associated with phenoconversion to an overt synucleinopathy, e.g. Parkinson's disease (PD), Lewy body dementia, and related disorders. Comorbid traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD)-henceforth "neurotrauma" (NT)-increase the odds of RBD by ~2.5-fold and are associated with an increased rate of service-connected PD in Veterans. Thus, RBD and NT are both independently associated with PD; however, it is unclear how NT influences neurological function in patients with RBD.

METHODS: Participants ≥18 years with overnight polysomnogram-confirmed RBD were enrolled between 8/2018 to 4/2021 through the North American Prodromal …

Sars-Cov-2 Neurotropism: Understanding Effects At The Blood-Brain Barrier And Hematogenous Neuroinvasiveness, Taylor E. Martinez

USF Tampa Graduate Theses and Dissertations

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for COVID-19, has provisional counts of over 110 million documented cases and 1.218 million deaths (as of February 2024) in the United States since January 2020. SARS-CoV-2 is an airborne respiratory virus that primarily infects the lungs via the ACE2 receptor but has well-documented secondary target organs including the kidneys, the gastrointestinal tract, the heart, and the skin. SARS-CoV-2 also infects the brain, but the hematogenous route of viral entry to brain is still not fully characterized. Understanding how SARS-CoV-2 traverses the blood-brain barrier (BBB) as well as how it …

Applying Decolonizing Theories And Methodologies In Archaeology To Two Collaborative Cultural Resource Management Projects, Cydney K. Lanthier

Dissertations and Theses

Decolonizing theories and methods were employed during two separate graduate research projects. The methods of the initial project were informed by political ecology, the landscape-level historical ecology theory, Tribal sovereignty, traditional ecological knowledge (TEK), Indigenous archaeology, and community based participatory research (CBPR). The initial project was based entirely on CBPR and purposed to gain National Register of Historic Places (NRHP) nomination as a Traditional Cultural Property (TCP) over a portion of the traditional landscape. This project was cancelled before completion. However, several methods involved in CBPR were employed before then. The second project took on more of the historical ecology …

Classroom Environment Analysis Via Internet Of Things, Kai-Yuan Tan, Kok-Why Ng, Kanesaraj Ramasamy

Journal of Informatics and Web Engineering

In this era of rapid technological advancement, the potential of the digital age has opened up numerous possibilities for our society. However, despite these advancements, traditional classrooms still lack the necessary technology to create an optimal learning environment for students. Consequently, students may struggle to effectively acquire knowledge within classrooms. This paper aims to conduct a classroom environment analysis using Internet of Things technology to gather data and uncover valuable insights. The proposed solution involves an embedded system for controlling and monitoring the classroom environment, as well as exporting historical data for further research. By ensuring accurate data collection, this …

Chronos Volume 8 Issue 1 - Full Issue

Chronos

No abstract provided.

Modernity And Brutality In Stalin's Russia And Hitler's Germany, Sara Klein

Chronos

No abstract provided.

Around The Center, 1992 June, Advocate Health - Midwest

Historical Documents - Combined

Illinois Masonic Medical Center, Chicago, IL: Issue of "Around the Center", an employee newsletter. This issue has staffing and departmental updates, patient letters, and photographs from the annual dinner dance and talent show.

نسبة توافر مهارات التفكير البصري في أنشطة دروس المهارات اللغوية وأنماطها في كتب "أُحبُّ لغتي" لصفوف الحلقة الأولى (4-1) من التعليم الأساسي بسلطنة عُمان, Aziz Salim Albusaidy, Fatima Muhammad Al-Kaf

Journal of the Association of Arab Universities for Research in Higher Education مجلة اتحاد الجامعات العربية للبحوث في التعليم العالي

هدف المقال إلى تحديد نسبة توافر مهارات التفكير البصري في أنشطة دروس المهارات اللغوية وأنماطها في كتب "أُحِبُّ لُغَتِي" لصفوف الحلقة الأولى (4-1) من التعليم الأساسي بسلطنة عُمان. استخدم الباحثان بطاقة تحليل محتوى مكونة من (22) مهارة، وقد تكون مجتمع الدراسة من أنشطة دروس مهارات اللغة العربية في كتب" أُحِبُّ لُغَتِي" لصفوف الحلقة الأولى (4-1) من التعليم الأساسي بسلطنة عُمان والبالغ عددها (527) نشاطا. وتوصلت الدراسة إلى النتائج الآتية: مهارة التعرّف على الشكل ووصفه أكثر مهارات التفكير البصري توافرا في أنشطة دروس المهارات اللغوية وأنماطها في كتب "أُحِبُّ لُغَتِي" لصفوف الحلقة الأولى (4-1) من التعليم الأساسي بسلطنة عُمان؛ حيث بلغت …

Flm177.1 Storytelling For Screens Example 1, Sae University College

Exemplars

A visual representation of the characters, story world, genre, and tone that the writer envisions for their narrative.

Hearing Before The United States Senate Committee On The Judiciary Subcommittee On Federal Courts, Oversight, Agency Actions, And Federal Rights, O. Carter Snead

Congressional Testimony

O. Carter Snead, the Charles E. Rice Professor of Law and director of the de Nicola Center for Ethics and Culture at the University of Notre Dame, offered expert testimony on Wednesday (June 12) before the U.S. Senate Committee on the Judiciary on “Crossing the Line: Abortion Bans and Interstate Travel for Care After Dobbs.”

Originally posted by the United States Senate Committee on the Judiciary.

Social Stigma Of Obesity In Neil Labute’S Fat Pig, : Rafal Thair Abdul Qadir, . Marwa Ghazi Mohammed

Uruk Journal of Human Sciences

Beauty standards are often influenced by social values ​​and cultural norms. What is considered to be beautiful has evolved over time and varies across cultures. These standards play a significant role in individuals' perceptions and behaviors about beauty. In addition, society places strong pressure on women to follow unrealistic beauty ideals. In today’s society, being slim is the ideal that women should follow. On the other hand, obese women are subjected to frequent judgments based on their weight and appearance. The constant exposure to social judgments and negative comments about their bodies can lead them to have body dissatisfaction, low …

Embracing The Oregon Way, Tony Salvador Ph.D.

Hatfield Graduate Journal of Public Affairs

No abstract provided.

Tactical Compromises: Authoritarian Survival Mechanisms Of Sudan’S Inqaz Regime (1989-2019), Dalia Abdelnabi

Theses and Dissertations

How did the Inqaz regime survive a civil war, economic crises, mass upheavals, and political stagnation for thirty years? This question guides the study’s analysis of the survival of one of the MENA’s most resilient authoritarian regimes. Authoritarian durability is an adaptive risk-taking process of implementing politically costly plans to survive in power. This research investigates authoritarian survival through power-sharing reforms and coup-proofing tactics. The study highlights the role of the autocratic ruling coalition in maintaining regime durability and argues that intra-elite dynamics are key to understanding an autocrat’s exit without a clear successor. To this end, I investigate the …

Which Tools Can Aid The Management Of Intangible Cultural Heritage In Community Based Heritage Organizations In Cairo? A Case Study Of Shubra’S Archive, Mienke Zwemstra

Theses and Dissertations

This thesis provides a comprehensive overview of cultural heritage management in Cairo, focusing particularly on intangible heritage and the potential benefits of digital tools in this field. It highlights the marginalization of community-based organizations in the broader narrative of heritage management in Cairo, along with the limited alignment and collaboration between local, national and international heritage institutions. Drawing from ethnographic research conducted at the Shubra’s Archive (SARD), this study identifies the challenges faced by such organizations, including the reliance on volunteers and international funding for mission implementation. It emphasizes the importance of strategic planning and collaboration with municipal and national …

The Inflammatory Exposome Of Major Depressive Disorder In An Egyptian Sample, Reem Deif

Theses and Dissertations

Major depressive disorder (MDD) has been recognized as a global public health concern affect-ing the lives of 264 million people with increasing prevalence worldwide. Inspired by the expo-somic research, this study aims to investigate the dynamic and complex interplay between dif-ferent demographic, lifestyle, environmental factors and bimolecular factors that are potentially involved in the pathology of MDD in a sample of Egyptian adults living in Cairo. This is in an attempt to acknowledge the biological underpinnings of MDD without underestimating the role of environmental influences. The context of Egypt provides richness to the current study given the national transition from …

How Do They See Us?: Unhcr's Representations Of Syrian Refugees In “Every Second Counts” Campaign, Marah Khalid

Theses and Dissertations

Representation is not just an opinion; it is the recreation of realities, facts, and stories that encourage receivers, who are readers and viewers, to build perceptions of a certain topic, objects, events, and human beings. Studying the representation of refugees in the media, UN agencies, and International organizations' press releases, videos, and images has been the main focus for many scholars for decades. However, little is known about refugees' perspectives on visuals produced by UN agencies. This research tries to add to the few studies concerning the captured human object, refugees, perspective using Hall’s encoding/decoding model (Hall, 1997) to analyze …

Feasibility Of Oil Palm Agroforestry System: Evaluating The Application Of Oil Palm Ash For Enhancing Cherry Tomato (Solanum Lycopersicum. Var. Nancy Rz) Production Using Brackish Water., Ime Joseph Bassey

Theses and Dissertations

Monoculture systems of oil palm production are ravaging the world’s tropical forests, causing deforestation and biodiversity loss, which contribute to climate change at an uncontrollable pace. Oil palm agroforestry systems (AFSs), one of the strategies of regenerative agriculture, have proven to reverse the unfavorable effects of the oil palm monoculture systems. A sustainable means of soil fertilization and irrigation must be explored to improve the feasibility of oil palm AFSs. This study evaluates the impact of the application of oil palm ash and brackish irrigation on cherry tomato production. The experiment was conducted in a hydroponic system using a 2*4 …

Impact Of Nano And Micro Analysis Studies On The Sustainability Of Products And Components, Ahmed A. Nour

Theses and Dissertations

Abstract

The emergence of Nano and Micro analysis has marked the beginning of a new era of substantial advancements across research disciplines and various industries. Utilizing Nano and Micro analysis methods and techniques holds a profound promise for advancements of materials, Healthcare and Medicine, Agricultural applications, Food science, Construction and Civil Engineering, Environmental Sustainability, Energy, and Transport & Automobile. Further, Nano and Micro analysis techniques and methods have made a substantial contribution to the 17 SDGs (Sustainable Development Goals). This work outlines a research endeavor that aims to investigate the impact of Nano and Micro analysis on the sustainability of …

Wayward Utopias: Time In Wilde And Goethe, Kafi Moghrabi Mr

Theses and Dissertations

In this thesis, I study the dialectical relation between the Utopian imagination and a reality perceived in every way as antagonistic to hope. In the first chapter, I present Ernst Bloch’s Utopian vision, as presented in The Principle of Hope, which offers an exposition of the author’s Romantic Marxism. The second chapter engages Oscar Wilde’s only novel, The Picture of Dorian Gray, demonstrating how a life devoted to self-gratification only results in the constant deferral of Utopian longing, and how, undone, Dorian’s demise opens up Utopian possibilities as anticipated by Bloch. Johann Wolfgang von Goethe’s version of the …

Winter Gps Tagging Reveals Home Ranges During The Breeding Season For A Borealnesting Migrant Songbird, The Goldencrowned Sparrow, Autumn R. Iverson, Diana L. Humple, Renée L. Cromier, Thomas P. Hahn, Theadora A. Block, Daizaburo Shizuka, Bruce E. Lyon, Alexis S. Chaine, Emily J. Hudson, Elisha M. Hull

School of Biological Sciences: Faculty Publications

Determining space use for species is fundamental to understanding their ecology, and tracking animals can reveal insights into their spatial ecology on home ranges and territories. Recent technological advances have led to GPS-tracking devices light enough for birds as small as ~30 g, creating novel opportunities to remotely monitor fine-scale movements and space use for these smaller species. We tested whether miniaturized GPS tags can allow us to understand space use of migratory birds away from their capture sites and sought to understand both pre-breeding space use as well as territory and habitat use on the breeding grounds. We used …

Associations Between Circadian Alignment And Cognitive Functioning In A Nationally Representative Sample Of Older Adults, Sophie Leahy, Qian Xiao, Chris Ho Ching Yeung, Mariana G Figueiro

Faculty, Staff and Student Publications

Proper alignment of activity-rest and light-dark patterns allows for healthy bodily functions to occur at optimal times of the day. Disruptions to this alignment may cause poor sleep as well as physical, mental, and cognitive problems. The purpose of this cross-sectional study was to determine if poorer circadian alignment was associated with decreased cognitive functioning among older (> 60 years) participants in the National Health and Nutrition Examination Survey. We utilized actigraphy-based rest-activity and dark-light measurements to calculate phasor magnitude (strength of circadian alignment coupling) and phasor angle (phase difference between activity-rest and light-dark cycles). Multiple linear regression models were …

Zinc Oxide Nanostructures Synthesized By Hot Water Treatment For The Photocatalytic Degradation Of Organic Pollutants In Water, Ranjitha Kumarapuram Hariharalakshmanan

Theses and Dissertations

Photocatalysis using nanostructured semiconductors for the degradation of organic pollutants has received significant attention as an advanced water treatment method. A photocatalyst absorbs light with energy greater than or equal to its band gap and generates electron-hole pairs. These electrons and holes take part in redox reactions in water to generate reactive oxygen species, such as hydroxyl radicals and superoxide anions, which can break down organic contaminants. However, this method has some challenges, such as electron-hole recombination, which reduces the efficiency, high cost of nanostructure synthesis, and reduced durability of nanostructured photocatalysts in suspension form. The immobilization of photocatalyst nanostructures …

Rest-Dependent Downregulation Of Von Hippel-Lindau Tumor Suppressor Promotes Autophagy In Shh-Medulloblastoma, Ashutosh Singh, Donghang Cheng, Jyothishmathi Swaminathan, Yanwen Yang, Yan Zheng, Nancy Gordon, Vidya Gopalakrishnan

Faculty, Staff and Student Publications

The RE1 silencing transcription factor (REST) is a driver of sonic hedgehog (SHH) medulloblastoma genesis. Our previous studies showed that REST enhances cell proliferation, metastasis and vascular growth and blocks neuronal differentiation to drive progression of SHH medulloblastoma tumors. Here, we demonstrate that REST promotes autophagy, a pathway that is found to be significantly enriched in human medulloblastoma tumors relative to normal cerebella. In SHH medulloblastoma tumor xenografts, REST elevation is strongly correlated with increased expression of the hypoxia-inducible factor 1-alpha (HIF1α)-a positive regulator of autophagy, and with reduced expression of the von Hippel-Lindau (VHL) tumor suppressor protein - a …