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Microglia In Post-Mortem Hippocampal Brain Tissue Of Male And Female Neonates After Hie, Kassandra M. Pulido, Angela N. Viaene, Amelia J. Eisch, Danielle G. Barber

Research Colloquium

Background: Hypoxic-ischemic encephalopathy (HIE) is the second-leading cause of neonatal morbidity and mortality worldwide. There are sex differences in the pathophysiology of HIE, particularly in microglia, which are critical in the immune response. Prior work highlights microglial aggregation in the hippocampus of human infants as a marker for HIE, but it is unknown whether this differs by sex.

Aim: We compare the microglial response in post-mortem hippocampal tissue from male and female neonates diagnosed with HIE vs. Controls who expired from other causes.

Methods: Using a retrospective cohort design, we reviewed medical records of neonates with hippocampal tissue in the …

Unique Considerations In The Management Of Healthcare Among Fertile Women A Case Report On Chronic Myeloid Leukemia And Pregnancy, Hermione Yamyo Monie, Taha Al Hassan, Salomon Pardo Roca, Uchechi Ehiemua, Ramiro Leal

Research Colloquium

Background: With the overturning of Roe v. Wade, the management of women who are family planning has become more complex, highlighting the necessity for comprehensive and informed healthcare. This case report underscores the importance of holistic, interdisciplinary care for women with chronic conditions like Chronic Myeloid Leukemia (CML) who are planning for pregnancy. The novelty lies in the interplay between oncological treatment and reproductive health under current legal constraints.

Case Presentation: We present the case of a 32-year-old woman, G2P0010, with a history of CML and a previous spontaneous abortion. Initially believed to be in remission, she was started …

New Insights Into The Mechanisms Of Skeletal Muscle Atrophy In Copd, Justin D. Mills, Hiram L. Garcia, Alex Zuo

Research Colloquium

Background: In 2020, it was estimated that there were over 480 million cases of chronic obstructive pulmonary disease (COPD) worldwide. Up to 40% of COPD patients suffer from certain degrees of muscle atrophy. The severity of this muscle atrophy is normally correlated with an increased mortality rate among these patients. The goal of this study is to underline the causes of muscle atrophy/dysfunction in the COPD population and to investigate treatment options.

Methods: We conducted an extensive literature review using the PubMed database, mainly focusing on publications from 2013 to 2024. Our objective was to identify the biological mechanisms underlying …

Ormeloxifene Suppresses Emt In Hepatocellular Carcinoma By Targeting Β-Catenin Signaling Pathway, Shabnam Malik, Mohammed Sikander, Daniel Zubieta, Anyssa Rodriguez, Murali Yallapu, Meena Jaggi, Subhash C. Chauhan

Research Colloquium

Background: Hepatocellular carcinoma (HCC) is one of the deadliest cancers, with a five-year survival rate. While Sorafenib (SRB) is the standard therapy, it is only effective in prolonging survival for some patients, emphasizing the urgent need for alternative treatment options. Resistance to apoptosis is a defining characteristic of cancer cells and a crucial factor in cancer recurrence and relapse. Although, anticancer potential of the FDA-approved compound Ormeloxifene (ORM), which has well-defined pharmacokinetic and pharmacodynamic properties, has been explored in a variety of cancers, its efficacy in HCC has remained unknown. Therefore, the purpose of this study was to investigate the …

Enhanced Bmp Signaling Via Alk2 In Osteoclasts Decreases Bone Density In Mice, Yolanda V. Gutierrez, Hiroyuki Yamaguchi, Yuji Mishina, Yoshihiro Komatsu

Research Colloquium

Bone remodeling is a complex biological process that has been extensively studied. Bone Morphogenetic Proteins (BMPs) are recognized as one of the critical growth factors that coordinate bone remodeling. Previous studies have demonstrated that BMP signaling in osteoclasts has a positive effect on osteoclast function. However, little is known about how each BMP type I receptors control osteoclastogenesis. To investigate this question, we utilized the Cre-LoxP system to specifically activate BMP signaling through ALK2 in mice. We utilized Cathepsin K (Ctsk)-Cre driver to activate BMP signaling in osteoclasts in mice. Compared with aged- and gender-matched controls, gain-of-function of BMP mutant …

Rape Culture And Female Resistance In Late Medieval Literature, With An Edition Of Middle English And Middle Scots Pastourelles, Grace Delmolino

Medieval Feminist Forum: A Journal of Gender and Sexuality

No abstract provided.

Beyond The Horizons Of Desire: Salme's Subjectivity In "Salman Und Morolf", Aysha M. Strachan

Medieval Feminist Forum: A Journal of Gender and Sexuality

Salme in the Middle High German epic poem Salman und Morolf (twelfth–fifteenth century) is conventionally read as a wild, dangerous, animalistic object waiting to be tamed by the men who fight for her hand. An in-depth analysis of her character is long overdue, and this article argues that Salme is a pertinent example of how female figures resist being “tamed” altogether. She is the movable object of multiple bridal quests for which she is ambiguously responsible. The unreachable, exoticized, and foreignized object of men’s desire, Salme embodies the drive of the western man to possess a fantasy of the Orient, …

Fictional Literary Biography, Sarah E. Novacich

Medieval Feminist Forum: A Journal of Gender and Sexuality

This essay examines how Lauren Groff’s novel, Matrix, creates a fictional life story for Marie de France as it minimizes the importance of the poetic corpus associated with that name. It reads this exchange of poetry for biography against a backdrop of medieval thinking about gender, language, and corporeality.

Effects Of Applied Nitrogen And Rest Period On Forage Production And Silage Quality, L Juan Carlos Dumont, A Francisco Lanuza

IGC Proceedings (1977-2023)

An experiment to analyse the effect of nitrogen (N) fertiliser and rest period initiation for silage making on permanent pasture was carried out. N fertiliser increased forage production, crude protein, neutral detergent fibre and ammonia-N. Shortening the intervals, by delaying the initiation of resting period, increased forage quality with only marginal decreases in dry matter (DM) production. Resting periods from the second week of September and cutting at the end of October or first week of November was appropriate in the Osorno area of Chile. The use of 60 kg N/ha is recommended. Two-cutting system must be considered in order …

The Burden Of Diabetes Mellitus In The Medically Underserved Rio Grande Valley, John M. Gaddis, Elias Arellano, Kassandra Pulido, Tyler Torres, Dominic Chau-Zanetti, Natasha Quailes, Andres Suarez Parraga

Research Colloquium

Introduction

Diabetes mellitus (DM) encompasses metabolic disorders characterized by elevated blood sugar. This study aimed to evaluate the prevalence and associated metrics of DM in the Rio Grande Valley (RGV), a low-income and medically underserved region in the United States, and compare these metrics to the national averages from 2012 to 2022.

Methods

A retrospective cross-sectional analysis was conducted using publicly accessible data from the Centers for Medicare and Medicaid Services (CMS). Metrics analyzed included DM prevalence, average principal cost, rates of emergency department visits, hospitalizations, screenings, and prevalence of obesity. Data from the RGV counties were compared to national …

Change In Botanical Composition, Dry Matter Yield And Forage Quality Of Grassland After Five Seasons Of Extensification, W Kuhbauch, J Schellberg

IGC Proceedings (1977-2023)

Extensification of grassland management in Germany has 2 major objectives (I) to reduce the surplus of crop and animal products, and (2) to diminish unwanted side effects against the environment from intensive production systems. Some of the programmes on offer require a reduced number of cuttings and grazings per season, including a very late first cut of the sward and a reduction of nitrogen fertiliser. In a 5-yenr experiment at the grassland research station Rengen, Eifel-mountain-range, Germany, extensification of this type on productive grassland sites created an unbalanced botanical composition and, with nitrogen applied, a major portion of quackgrass in …

Efficiency Of Different Implements For Pasture Interseeding, J A. Josifovich

IGC Proceedings (1977-2023)

Pasture renovation with grasses and legumes appears to be a good practice to increase primary and secondary production. Trials were planted in 6 locations in Buenos Aires province, Argentina, 2 in Pergamino and 4 200 and 300 km south east of Pergamino, to evaluate 3 different implement combinations: a) rigid chisel coulter, b) spring tooth heavy duty coulter, with teeth 30 cm apart followed by spring tooth cultivators, and c) spring tooth heavy duty coulter 30 cm used twice in the same direction. The species sown were: fescue (Festuca arundinacea Schreb.), brome (Bromus uniolides H.B.K.), chicory (Cichoriu, intybus …

Role Of Mixed Animal Type Grazing In Range Preservation And Increasing Animal Product Output, T Nolan, J Connolly, C Sall

IGC Proceedings (1977-2023)

fhe work was part of a research programme to a) evaluate the role of mixed animal type grazing in increasing production, b) explain any; benefits obtained and c) develop improved whole grazing ecosystems in temperate and semi-arid areas. Its specific ai was to improve domestic food production from range grazing livestock and to preserve or improve native range resources. This paper discusses some recent results from the Senegalese Sahel related to· animal preferential and differential selection, animal performance and the role of mixed grazing in improving the relationships between them to secure the objectives stated. The use of these results …

Effect Of Grass-White Clover Mixtures On Steer Performance And Sward Characteristics In Atlantic Canada, H T. Kunelius, P Narasimhalu

IGC Proceedings (1977-2023)

Pasture production in winter cold regions such as Atlantic Canada is limited by the availability of winter hardy and productive grass and legume species, Perennial ryegrass (Lolium perenne L.), meadow fescue (Festuca prarensis Huds.) and timothy (Phleum pratense L.) grown in binary mixtures with white clover (Trifolium repens L.), and naturalised pasture consisting of Poa spp., Agrostis spp. and white clover, were compared under grazing, Steers were used to graze the swards from 16-26 cm down to 8 or 11 cm post-grazing surface heights, Dry matter intake was higher for natural pasture than for sown pastures, …

Range Management: Optimizing Forage Production And Qualityy, J E. Danckwerts, N M. Tainton

IGC Proceedings (1977-2023)

Range management involves optimising forage production and quality, both in the short term and in the long term. In the short term, temporal climatic variability, stocking rate, grazing system, fire, animal type. and spatial variability, inter alia, strongly, influence forage production and quality. On the other hand, long-term optimisation requires prevention of range deterioration. The nature of this process seems to be profoundly different between humid and arid rangelands, at least in tropical and subtropical zones. In the former, changes are relatively predictable, overgrazing resulting in gradual deterioration. In the latter, change is event driven, providing the grazier with …

Livestock Production Systems In The Cameroon Sahelo-Sudanian Region, E Tedonkeng Pamo, R D. Pieper

IGC Proceedings (1977-2023)

The Sahelo-Sudanian region of Cameroon extends from 7° to 13° N. The region receives 400-1000 mm rainfall and is covered by a complex mosaic of. vegelation and plant communities. Animal production has always been a cornerstone of the economy of this region. The range use system of the region is extensive. The major problem faced by pastoralists has been a compression of their range not only by the northward-moving cultivation, but also by the southward moving desertification. Various grazing melhods have been suggested but none have yet been implemented, and nomadism and transhumance remain the major production systems. Analysis of …

Reduction Of Nutrient Losses For Dairy Farms, With Emphasis On Nitrogen, W Luten, D J. Den Boer

IGC Proceedings (1977-2023)

Recently the Dutch government presented several policy papers in which standards are given for maximum allowed emissions to air, groundwater and surface water. Depending on the farm situation an optimum combination of measures in relation to housing, slurry storage, slurry and fertiliser application, and composition of the ration can be taken. In general a better use of nutrients from animal manure by applying slurry with low emission techniques in the growing season and a reduction of the stocking rate by a higher milk production per cow are the most effective and cheapest measures to reach these targets. There is a …

Necrotic Lung Tumor Mimicking Primary Pulmonary Abscess On Computed Tomographic Imaging Study In A Dyspneic Dog, Mihyun Choi, Namsoon Lee

The Thai Journal of Veterinary Medicine

A 14-year-old spayed female Shih-Tzu dog was evaluated for a 1-month history of progressive coughing. Results of the complete blood count and serum biochemistry panel indicated inflammation. Thoracic radiography showed pleural effusion, and cytology revealed septic pyothorax. After antibiotics medication, the patient improved clinical signs but relapsed pleural effusion with a suspicious lung lesion. Computed tomography (CT) of the thorax showed a cavitary lesion with ring-enhanced irregular walls and poorly defined margins in the left cranial lung lobe. The main differential diagnosis considered was lung abscess, but the histopathological diagnosis was necrotic lung adenocarcinoma. This case suggests that both a …

Molecular Detection Of Mycoplasma Spp. And Its Associated Risk Factors In Domestic Cats In The City Of Ibagué, Tolima, Karen D. Osorio Muñoz Dr., Iang S. Rondon Barragan Prof.

The Thai Journal of Veterinary Medicine

Feline hemoplasmosis is a disease with worldwide distribution, mainly in tropical countries, where its transmission is favored by the presence of vectors such as fleas and ticks. In Colombia, the diagnosis of the disease in small animals has been limited to the identification of the pathogen in blood smears, which have low sensitivity and specificity, demanding methods of higher diagnostic value, such as those based on molecular techniques. The objective of the present study was to investigate the prevalence of Mycoplasma spp. in felines from the city of Ibagué using the PCR and the associated risk factors. Briefly, blood samples …

Global Prevalence And Zoonotic Potential Of Cryptosporidiosis In Camels (Camelus Dromedarius): Systematic Meta-Analysis, Mohamed Marzok, Hussein Babiker, Mohamed Tharwat, Sabry El-Khodery

The Thai Journal of Veterinary Medicine

In this study, meta-analysis on prevalence and zoonotic significance of cryptosporidium infection in camels was performed. This study was completed following the instructions of PRISMA. Data were extracted afterward a complete search, and eligible articles were identified. The data were analyzed using a specific software program for meta-analysis, and the results included effect size, confidence intervals (CI), heterogeneity, and publication bias. A total of 4075 camels from 18 accepted studies were investigated for cryptosporidium infection. Of all, 287 camels were found positive for cryptosporidium infection, with a prevalence of 7.04%. The prevalence of cryptosporidiosis in camels varied significantly among …

Risk Factors Of Bovine Clinical Mastitis And Antimicrobial Resistance Of Mastitis-Causing Escherichia Coli In Shandong, China, Liu Peng, Dongfang Hu, Jinjiao Zuo, Caihong Wu, Hui Lu, Zilong Cheng, Mengda Liu

The Thai Journal of Veterinary Medicine

The culling of dairy cattle is closely related to the economic benefits of the farm. Many reasons can lead to the culling of cows. Among these, mastitis is the main reason for the serious economic loss of the dairy industry, and also the harm to global public health. However, little is known about cow culling situations, antimicrobial resistance, and virulence factors of mastitis-causing Escherichia coli in Shandong, China. A cross-sectional study was conducted in 16 randomly selected dairy herds to identify the reasons for cow culling, to assess the risk factors, and to isolate the major etiological agent of clinical …

Leo-Trap: Application Of The Lethal Ovitrap For Controlling Vectors Of Dengue Fever In Chiang Mai Province, Thailand, Suttida Suwannayod, Usavadee Thavara, Navy Srivarom, Payu Bhakdeenuan, Apiwat Tawatsin, Padet Siriyasatien

The Thai Journal of Veterinary Medicine

Mosquito-borne diseases transmitted by Aedes mosquitoes in Thailand, including dengue hemorrhagic fever, chikungunya, and Zika viruses, are major health concerns. To address this, the LeO-Trap is an ovitrap with the potential for controlling disease vectors. This research aimed to assess the effectiveness of the LeO-Trap in a high-risk urban area in Chiang Mai province, Thailand. The study area chosen, due to the number of dengue cases, encompassed two villages in Mae Rim district, each with over 100 homes. From May to July 2021, four LeO-Traps were deployed in every home - two indoors and two outdoors. Ovitrap Index (OI) and …

Bovine Respiratory Syncytial Virus: First Identification In Eastern Algeria Based On Direct Immunofluorescence And Elisa Tests, Imene Abdelmalek, Bakir Mamache, Amine Boudaoud, Yacine Khanfri

The Thai Journal of Veterinary Medicine

Bovine respiratory syncytial virus (BRSV) is the main agent of the bovine respiratory disease complex (BRD). Its circulation among the Algerian bovine population has been strongly suspected but never confirmed. This study investigated the prevalence of BRSV in cattle in eastern Algeria. From 2022 to 2023, a total of 225 serum and 102 lung tissue samples were collected from farms and slaughtered cattle of different ages. Samples were tested for BRSV antibodies by Enzyme-Linked Immunosorbent Assay (ELISA) and BRSV antigens by Direct Immunofluorescence Test (DFAT). Histopathological examination was also performed on lung tissue sections. BRSV-specific antibodies were detected in 91.11% …

Casein Gene Polymorphism Of Goat In Thailand, Naparat Naowanat, Duangsmorn Suwattana, Boonnarong Suphap

The Thai Journal of Veterinary Medicine

The genetic polymorphism of the casein genes and the evaluation of haplotype variability in Saanen and Thai Native breeds in Thailand were investigated. The 23 Saanen and 42 Thai Native goats were genotyped at CSN1S1, CSN2, CSN1S2, and CSN3 loci using sequencing techniques. Three variants of A, C, and E on the CSN1S1 gene locus were demonstrated. The genotypic frequencies of CSN1S1 AA, AC, and AE are shared by over 80% of the population. The CSN2 A and F alleles were observed. The CSN2 genotypes of AA, AF, and FF were indicated with the majority of AF frequency. The 2 …

Index To Volume 37

Marvels & Tales

Index

Reviews

Marvels & Tales

Book reviews

Introduction To The Special Issue: Literary Fairy Tales And The Embodied Mind, Francesca Arnavas, Marzia Beltrami

Marvels & Tales

Introduction to the Special Issue

Pms 6 (End Matter), Poemmemoirstory Staff

PoemMemoirStory (literary magazine)

pp. 145-151

The White Space Between The Blue Lines, Cathy Warner

PoemMemoirStory (literary magazine)

pp. 101-103

The Accident, Marianne Taylor

PoemMemoirStory (literary magazine)

p. 17