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Diversity Of Platyhelminthes, Xenacoelomorpha, Nematoda, Acanthocephala, Brachiopoda, Kinorhyncha, Nemertea, Chaetognatha, Tardigrada, Gastrotricha, Rotifera, Phoronida, Echinodermata And Chordata (Tunicata, Cephalochordata And Hemichordata) From The Coasts Of Türkiye, Meli̇h Ertan Çinar, Derya Ürkmez, Baki̇ Yokeş Oct 2024

Diversity Of Platyhelminthes, Xenacoelomorpha, Nematoda, Acanthocephala, Brachiopoda, Kinorhyncha, Nemertea, Chaetognatha, Tardigrada, Gastrotricha, Rotifera, Phoronida, Echinodermata And Chordata (Tunicata, Cephalochordata And Hemichordata) From The Coasts Of Türkiye, Meli̇h Ertan Çinar, Derya Ürkmez, Baki̇ Yokeş

Turkish Journal of Zoology

The current biodiversity of 14 phyla, namely Platyhelminthes, Xenacoelomorpha, Nematoda, Acanthocephala, Brachiopoda,Kinorhyncha, Nemertea, Chaetognatha, Tardigrada, Gastrotricha, Rotifera, Phoronida, Echinodermata, and Chordata (invertebratesonly, including the subphyla Tunicata, Cephalochordata, and Hemichordata) from the coasts of Türkiye is revisited. It was found thata total number of 695 species occur along all the coastlines of Türkiye, with the Black Sea being represented by 297 species, the Sea ofMarmara by 305 species, the Aegean Sea by 308 species, and the Levantine Sea by 204 species. The most species-rich phyla in theseregions were Platyhelminthes (249 species), Nematoda (131), Echinodermata (98), and Chordata (85). A total of …


Diversity Of Annelida From The Coasts Of Türkiye, Meli̇h Ertan Çinar, Şermi̇n Açik, Güley Kurt, Deni̇z Erdoğan Dereli̇ Oct 2024

Diversity Of Annelida From The Coasts Of Türkiye, Meli̇h Ertan Çinar, Şermi̇n Açik, Güley Kurt, Deni̇z Erdoğan Dereli̇

Turkish Journal of Zoology

The compilation of scientific papers dealing with marine annelids (including Sipuncula) along the coasts of Türkiye (Black Sea, Sea of Marmara, Aegean Sea and Levantine Sea) together with the new records of polychaete species (22 species) presented in this study resulted in 827 species belonging to 63 families. Polychaeta were represented by 782 species, Sipuncula by 21 species, Oligochaeta by 18 species, Hirudinea by 5 species and Echiura by 1 species. Syllidae (127 species), Spionidae (57 species) and Serpulidae (56 species) were the most species-rich families and their numbers varied among the seas. Most annelid species were benthic (808 species), …


Diversity Of Mollusca Along The Coasts Of Türkiye, Bi̇lal Öztürk, Banu Bi̇tli̇s, Nesli̇han Türkçü Oct 2024

Diversity Of Mollusca Along The Coasts Of Türkiye, Bi̇lal Öztürk, Banu Bi̇tli̇s, Nesli̇han Türkçü

Turkish Journal of Zoology

The present study is based on a species list published in 2014 and a compilation of data from papers on marine molluscs along the coasts of Türkiye published from that date until the end of April 2024, along with six new records presented herein. Mollusca were represented by 1133 species classified into 7 classes, 255 families and 617 genera on the Turkish coasts. The Pyramidellidae (92 species) and Rissoidae (64 species) were species-rich mollusc families. Most of the listed molluscs were benthic, except for 26 pelagic species and 119 parasitic taxa. The Aegean Sea has the highest number of species …


Diversity Of Marine Arthropoda Along The Coasts Of Türkiye, Ahmet Kerem Bakir, Hali̇m Vedat Aker, Özge Özgen, Furkan Durucan Oct 2024

Diversity Of Marine Arthropoda Along The Coasts Of Türkiye, Ahmet Kerem Bakir, Hali̇m Vedat Aker, Özge Özgen, Furkan Durucan

Turkish Journal of Zoology

The aim of this publication is to compile an updated list of marine arthropod species reported from the coasts of Türkiye. As of the first half of 2024, a total of 1886 arthropod species have been reported in the marine and brackish water environments of Türkiye. The class Malacostraca, having the highest number of species, is followed by Copepoda, Ostracoda, Arachnida, Pycnogonida, Thecostraca, Branchiopoda, and Insecta in terms of species diversity. Additionally, 83 alien species have been identified.


Diversity Of Fishes Along The Coast Of Türkiye, Murat Bi̇lecenoğlu Oct 2024

Diversity Of Fishes Along The Coast Of Türkiye, Murat Bi̇lecenoğlu

Turkish Journal of Zoology

The Turkish marine fish diversity was revised and updated in this study based on data published in the last decade. There arecurrently 552 species in the inventory, reflecting an increase of 7.8% since the previous checklist and belonging to the classes of Teleostei(479 spp.), Elasmobranchii (68 spp.), Chondrostei (3 spp.), Petromyzonti (1 sp.), and Holocephali (1 sp.). Twelve species were excludedfrom the faunal list due to the lack of valid proof of their presence, the distribution ranges of an additional 12 species were corrected, twonew records (Istiompax indica (Cuvier, 1832) and Mola alexandrini (Ranzani, 1839)) previously unknown from Türkiye were …


Diversity Of Marine Tetrapods (Reptiles, Seabirds, And Mammals) Along The Coasts Of Türkiye, Harun Güçlüsoy, Ortaç Onmuş Oct 2024

Diversity Of Marine Tetrapods (Reptiles, Seabirds, And Mammals) Along The Coasts Of Türkiye, Harun Güçlüsoy, Ortaç Onmuş

Turkish Journal of Zoology

This paper presents the occurrence of a total of 72 marine tetrapod species, comprising 3 sea turtles, 54 seabirds, and 15 marine mammals. The distribution of each reported species along the Black Sea, Sea of Marmara, Aegean, and Levantine coasts of Türkiye is described with key references.


Presentation And Study Of The Manuscript Entitled “The Sign Of Happiness In Habitual Foods By Doctor Abu Al-Hasan Ali Ibn Hassan Al-Marakshi”, Abdelhamid Bitari, Rachid Touzani, Belkheir Hammouti, Abdelkhaleq Legssyer Oct 2024

Presentation And Study Of The Manuscript Entitled “The Sign Of Happiness In Habitual Foods By Doctor Abu Al-Hasan Ali Ibn Hassan Al-Marakshi”, Abdelhamid Bitari, Rachid Touzani, Belkheir Hammouti, Abdelkhaleq Legssyer

An-Najah University Journal for Research - B (Humanities)

Introduction: Morocco preserves manuscripts of significant scientific and cultural value, which require presentation, verification, and study. The importance of studying the book "The Sign of Happiness in Common Foods" lies in the fact that it serves as a scientific reference point for understanding the principles of nutrition and medicinal herbs during the Middle Ages, especially in the Islamic world. Objective: Manuscript books represent a cultural and scientific treasure for Moroccan and humanity civilizations. Therefore, they require uncovering, displaying, and studying. Our work in this context involves presenting and studying the manuscript book titled "The Sign of Happiness in Usual Foods …


Spartan Daily, October 2, 2024, San Jose State University, School Of Journalism And Mass Communications Oct 2024

Spartan Daily, October 2, 2024, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2024

Volume 163, Issue 17


Diversity Of Bryozoa Along The Coasts Of Türkiye, Ferah Koçak, Si̇nem Aydin Oct 2024

Diversity Of Bryozoa Along The Coasts Of Türkiye, Ferah Koçak, Si̇nem Aydin

Turkish Journal of Zoology

The current status of bryozoan species distributed along the coast of Türkiye were revised and an updated checklist including 185 species (24 cyclostomatids, 20 ctenostomatids and 141 cheilostomatids) was presented. Cheilostomes largely prevail (141 species, 87 genera and 50 families) followed by cyclostomes (24 species, 15 genera and 9 families) and ctenostomes (20 species, 9 genera and 8 families) in bryozoan fauna of Türkiye. The distribution of species and genera highlights the Aegean Sea as the most diverse, hosting 146 species. In this study, Hornera frondiculata (Lamarck, 1816), Amathia verticillata (delle Chiaje, 1822), Bugulina fulva (Ryland, 1960), Tricellaria inopinata d'Hondt …


Analyses Of Whole-Genome Sequences From 185 North American Thoroughbred Horses, Spanning 5 Generations, Ernie Bailey, Carrie J. Finno, Jonah N. Cullen, Ted Kalbfleisch, Jessica Lynn Petersen Oct 2024

Analyses Of Whole-Genome Sequences From 185 North American Thoroughbred Horses, Spanning 5 Generations, Ernie Bailey, Carrie J. Finno, Jonah N. Cullen, Ted Kalbfleisch, Jessica Lynn Petersen

Department of Animal Science: Faculty Publications

Whole genome sequences (WGS) of 185 North American Thoroughbred horses were compared to quantify the number and frequency of variants, diversity of mitotypes, and autosomal runs of homozygosity (ROH). Of the samples, 82 horses were born between 1965 and 1986 (Group 1); the remaining 103, selected to maximize pedigree diversity, were born between 2000 and 2020 (Group 2). Over 14.3 million autosomal variants were identified with 4.5–5.0 million found per horse. Mitochondrial sequences associated the North American Thoroughbreds with 9 of 17 clades previously identified among diverse breeds. Individual coefficients of inbreeding, estimated from ROH, averaged 0.266 (Group 1) and …


Coyotes Can Do ‘Puppy Dog Eyes’ Too: Comparing Interspecific Variation In Canis Facial Expression Muscles, Patrick Cunningham, Mahita Shankar, Bridgett Vonholdt, Kristin Brzeski, Sarah S. Kienle Oct 2024

Coyotes Can Do ‘Puppy Dog Eyes’ Too: Comparing Interspecific Variation In Canis Facial Expression Muscles, Patrick Cunningham, Mahita Shankar, Bridgett Vonholdt, Kristin Brzeski, Sarah S. Kienle

Michigan Tech Publications

Facial expressions are critical for non-verbal communication. The Canis genus epitomizes the interplay between behaviour and morphology in the evolution of non-verbal communication. Recent work suggests that the levator anguli oculi medialis (LAOM) muscle is unique to dogs (Canis familiaris) within the Canis genus and evolved due to domestication. The LAOM raises the inner eyebrows, resulting in the ‘puppy dog eyes’ expression. Here, we test whether the LAOM is a derived trait in dogs by (i) examining the facial expression muscles of a closely related and ancestral wild Canis species, the coyote (C. latrans) and (ii) comparing our results with …


In-Situ, High-Throughput Dna Sequencing And Methodology Refinement To Survey Biodiversity And Identify Candidate New Species To Science In A Largely Unprotected Biological Corridor In Ecuador, Christian Boudreaux Oct 2024

In-Situ, High-Throughput Dna Sequencing And Methodology Refinement To Survey Biodiversity And Identify Candidate New Species To Science In A Largely Unprotected Biological Corridor In Ecuador, Christian Boudreaux

Venture: The University of Mississippi Undergraduate Research Journal

The world is undergoing a biodiversity crisis in which hundreds of species have gone extinct within the last few centuries, rivaling previous mass extinction events that have only occurred five times in the history of the planet. Anthropogenic stressors such as the climate crisis, over exploitation of natural resources, deforestation, and pollution have created and fostered a mass extinction event that is taking place in every corner of the planet. Endemic species, those that are hyper-specialized to specific environmental conditions are most at risk of going extinct. Endemism, therefore, is used as a tool for conservation and as an indicator …


Link’S Sword Is Mightier Than The Pen: Composing And Performing In The Super Mario And Legend Of Zelda Series, William Nelson Oct 2024

Link’S Sword Is Mightier Than The Pen: Composing And Performing In The Super Mario And Legend Of Zelda Series, William Nelson

Venture: The University of Mississippi Undergraduate Research Journal

Player interaction has largely defined video games and their concomitant music. Since Pong (1972), players have exercised agency over both in-game events and, by extension, the sounds that accompany them. In this paper, I explore ways in which the “authorial agency” of the player is reflected musically in Nintendo’s Super Mario (1985–) and The Legend of Zelda (1986–) series. Through earcons and other interactive audio, players are able to influence the musical architecture of video games. I begin by considering the indeterminacy of video games as a medium and their consequently indeterminate musical elements. I then examine earcons and the …


Cover And Contents Oct 2024

Cover And Contents

Turkish Journal of Zoology

No abstract provided.


October 2, 2024 (Vol. 109, No. 6), Daily Eastern News Oct 2024

October 2, 2024 (Vol. 109, No. 6), Daily Eastern News

Daily Eastern News: 2024-2025

No abstract provided.


The Lumberjack, October 02, 2024 Oct 2024

The Lumberjack, October 02, 2024

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.


More Than Memory: Can Memory Spaces Really Prevent Mass Atrocities?, Kerry E. Whigham Oct 2024

More Than Memory: Can Memory Spaces Really Prevent Mass Atrocities?, Kerry E. Whigham

Genocide Studies and Prevention: An International Journal

As transitional justice has grown as a field and as an international mandate in post-atrocity contexts over the past several decades, the memorialization of past atrocities through the construction of physical spaces of memory has increasingly been recognized as an essential aspect of this complex process. Often, these spaces of memory are touted not only as honoring past victims, but also as important tools for preventing future violence. To date, there has yet to emerge a clear way to measure exactly how sites of memory contribute to atrocity prevention. Can a site of memory really help prevent further acts of …


Bridging The Atrocity Prevention Gap Between The International And The Local: Lessons Learned From Meso-Level Leadership In Ukraine And Syria, Kristina Hook, Jamie D. Wise Oct 2024

Bridging The Atrocity Prevention Gap Between The International And The Local: Lessons Learned From Meso-Level Leadership In Ukraine And Syria, Kristina Hook, Jamie D. Wise

Genocide Studies and Prevention: An International Journal

This paper explores meso-level approaches to atrocity prevention that incorporate a wider array of local expertise at all stages, from early warning to transitional justice. Specifically, we treat meso-level approaches as encompassing local leadership and advocacy across bottom-up processes, grassroots efforts, victim-led activism, and civil society mobilization. We draw from two contemporary cases of mass atrocities, Ukraine and Syria, which exemplify such efforts, using primary interview data with meso-level actors. First, we examine atrocity risk early warning in Ukraine, where prescient local expertise at the meso-level failed to influence international responses, asking what went wrong and what more could be …


Pig Butchering In Cybersecurity: A Modern Social Engineering Threat, Sharon L. Burton, Pamela D. Moore Oct 2024

Pig Butchering In Cybersecurity: A Modern Social Engineering Threat, Sharon L. Burton, Pamela D. Moore

Publications

Pig butchering is an escalating cybersecurity threat that exploits social engineering to build trust and execute financial fraud. The relevance of this research problem lies in the growing incidence and sophistication of these scams, which have severe financial and psychological impacts on victims. The main purpose of this research is to uncover the methods used in pig butchering scams and their impact on individuals and businesses. The research focuses on digital platforms such as social media, dating apps, and professional networking sites, chosen for their wide user bases and the ease of establishing personal connections. The study period encompasses recent …


Gastronomical Platonism, Marco Panza Oct 2024

Gastronomical Platonism, Marco Panza

MPP Published Research

The paper presents a Platonist approach to the art of cooking, based on a crucial distinction between taste and flavor. Being Platonist in cooking is surely not the same as being so in mathematics and logic. Göran is not so in these fields, but I'm confident, that as many mathematicians are spontaneously inclined to live in a Platonist heaven, the sophisticated cook and eater that Göran is will be pleased to imagine with me a Platonist realm of flavors.


The Parthenon, October 02, 2024, Evan Green, Sarah Davis, Baylee Parsons, Joseph Dicristofaro, Kaitlyn Fleming, Scott Price, Abigail Cutlip, Rafael Alfonso, Wade Sullivan Oct 2024

The Parthenon, October 02, 2024, Evan Green, Sarah Davis, Baylee Parsons, Joseph Dicristofaro, Kaitlyn Fleming, Scott Price, Abigail Cutlip, Rafael Alfonso, Wade Sullivan

The Parthenon

No abstract provided.


Dangerous Speech As An Atrocity Early Warning Indicator: Measuring Changing Conflict Dynamics, Catherine Buerger, Susan Benesch Oct 2024

Dangerous Speech As An Atrocity Early Warning Indicator: Measuring Changing Conflict Dynamics, Catherine Buerger, Susan Benesch

Genocide Studies and Prevention: An International Journal

Dangerous speech, any expression that can increase the likelihood that someone will commit or condone violence against members of another group, can be a powerful early warning signal of impending mass violence. However, one cannot make a list of words that are dangerous, since the effect of the message depends not only on its content, but also on how it is communicated: by whom, to whom, and under what circumstances. What may be benign in one context may be extremely inflammatory in another. Thus, effective monitoring requires deep knowledge of the local setting and structural factors. The spread of dangerous …


Vegetation Invasion Influences Waterbird Assemblages And Aquatic Environmental Parameters In Urban Areas Of Dar Es Salaam, Tanzania, Daudi O. Damas, Jasson R. John Oct 2024

Vegetation Invasion Influences Waterbird Assemblages And Aquatic Environmental Parameters In Urban Areas Of Dar Es Salaam, Tanzania, Daudi O. Damas, Jasson R. John

Tanzania Journal of Science

Waste Stabilisation Ponds (WSPs) serve as refuge habitats for waterbirds in response to the decline of natural wetlands especially in urban settings. Various sewage treatment stages within WSPs attract waterbirds differently based on the specific characteristics of each stage. This study examines the influence of treatment stages on both vegetated and non-vegetated WSPs over a period of one year in Dar es Salaam, Tanzania. Bird surveys were periodically conducted at each treatment stage along with different environmental variables; dissolved oxygen, electrical conductivity, water turbidity, water temperature, pH, and invertebrate biomass. In non-vegetated WSPs, waterbird densities and invertebrate biomass were significantly …


Spectrum, Issue 53, Number 4, Sacred Heart University Oct 2024

Spectrum, Issue 53, Number 4, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: SHU M.E.N. Making their Mark on Nursing - Family Weekend Festivities Planned --Concerns for Safety in Local Elementary and High Schools -- From 30 Rock to 5151 Park Avenue: Meet Prof. Joe Alicastro


Synergic Activity Of Fgfr2 And Mek Inhibitors In The Treatment Of Fgfr2-Amplified Cancers Of Unknown Primary, Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Francesco Gelsomino, Mattia Riefolo, Karim Rihawi, Elisa Porcellini, Tania Rossi, Martina Mazzeschi, Maria Naddeo, Salvatore Serravalle, Elisabetta Broseghini, Federico Agostinis, Olivier Deas, Roberta Roncarati, Giorgio Durante, Ilaria Pace, Mattia Lauriola, Ingrid Garajova, George A Calin, Massimiliano Bonafè, Antonia D'Errico, Pier Giorgio Petronini, Stefano Cairo, Andrea Ardizzoni, Gabriele Sales, Manuela Ferracin Oct 2024

Synergic Activity Of Fgfr2 And Mek Inhibitors In The Treatment Of Fgfr2-Amplified Cancers Of Unknown Primary, Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Francesco Gelsomino, Mattia Riefolo, Karim Rihawi, Elisa Porcellini, Tania Rossi, Martina Mazzeschi, Maria Naddeo, Salvatore Serravalle, Elisabetta Broseghini, Federico Agostinis, Olivier Deas, Roberta Roncarati, Giorgio Durante, Ilaria Pace, Mattia Lauriola, Ingrid Garajova, George A Calin, Massimiliano Bonafè, Antonia D'Errico, Pier Giorgio Petronini, Stefano Cairo, Andrea Ardizzoni, Gabriele Sales, Manuela Ferracin

Faculty, Staff and Student Publications

Patients with cancer of unknown primary (CUP) carry the double burden of an aggressive disease and reduced access to therapies. Experimental models are pivotal for CUP biology investigation and drug testing. We derived two CUP cell lines (CUP#55 and #96) and corresponding patient-derived xenografts (PDXs), from ascites tumor cells. CUP cell lines and PDXs underwent histological, immune-phenotypical, molecular, and genomic characterization confirming the features of the original tumor. The tissue-of-origin prediction was obtained from the tumor microRNA expression profile and confirmed by single-cell transcriptomics. Genomic testing and fluorescence in situ hybridization analysis identified FGFR2 gene amplification in both models, in …


Synergic Activity Of Fgfr2 And Mek Inhibitors In The Treatment Of Fgfr2-Amplified Cancers Of Unknown Primary, Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Francesco Gelsomino, Mattia Riefolo, Karim Rihawi, Elisa Porcellini, Tania Rossi, Martina Mazzeschi, Maria Naddeo, Salvatore Serravalle, Elisabetta Broseghini, Federico Agostinis, Olivier Deas, Roberta Roncarati, Giorgio Durante, Ilaria Pace, Mattia Lauriola, Ingrid Garajova, George A Calin, Massimiliano Bonafè, Antonia D'Errico, Pier Giorgio Petronini, Stefano Cairo, Andrea Ardizzoni, Gabriele Sales, Manuela Ferracin Oct 2024

Synergic Activity Of Fgfr2 And Mek Inhibitors In The Treatment Of Fgfr2-Amplified Cancers Of Unknown Primary, Andrea Cavazzoni, Irene Salamon, Claudia Fumarola, Giulia Gallerani, Noemi Laprovitera, Francesco Gelsomino, Mattia Riefolo, Karim Rihawi, Elisa Porcellini, Tania Rossi, Martina Mazzeschi, Maria Naddeo, Salvatore Serravalle, Elisabetta Broseghini, Federico Agostinis, Olivier Deas, Roberta Roncarati, Giorgio Durante, Ilaria Pace, Mattia Lauriola, Ingrid Garajova, George A Calin, Massimiliano Bonafè, Antonia D'Errico, Pier Giorgio Petronini, Stefano Cairo, Andrea Ardizzoni, Gabriele Sales, Manuela Ferracin

Faculty, Staff and Student Publications

Patients with cancer of unknown primary (CUP) carry the double burden of an aggressive disease and reduced access to therapies. Experimental models are pivotal for CUP biology investigation and drug testing. We derived two CUP cell lines (CUP#55 and #96) and corresponding patient-derived xenografts (PDXs), from ascites tumor cells. CUP cell lines and PDXs underwent histological, immune-phenotypical, molecular, and genomic characterization confirming the features of the original tumor. The tissue-of-origin prediction was obtained from the tumor microRNA expression profile and confirmed by single-cell transcriptomics. Genomic testing and fluorescence in situ hybridization analysis identified FGFR2 gene amplification in both models, in …


Neuron-Glial Interactions: Implications For Plasticity, Behavior, And Cognition, Mauricio Rangel-Gomez, Cristina M Alberini, Benjamin Deneen, Gabrielle T Drummond, Tiina Manninen, Mriganka Sur, Aleksandra Vicentic Oct 2024

Neuron-Glial Interactions: Implications For Plasticity, Behavior, And Cognition, Mauricio Rangel-Gomez, Cristina M Alberini, Benjamin Deneen, Gabrielle T Drummond, Tiina Manninen, Mriganka Sur, Aleksandra Vicentic

Faculty, Staff and Students Publications

The traditional view of glial cells as mere supportive tissue has shifted, due to advances in technology and theoretical conceptualization, to include a diversity of other functions, such as regulation of complex behaviors. Astrocytes, the most abundant glial cells in the central nervous system (CNS), have been shown to modulate synaptic functions through gliotransmitter-mediated neurotransmitter reuptake, influencing neuronal signaling and behavioral functions. Contemporary studies further highlight astrocytes' involvement in complex cognitive functions. For instance, inhibiting astrocytes in the hippocampus can lead to memory deficits, suggesting their integral role in memory processes. Moreover, astrocytic calcium activity and astrocyte-neuron metabolic coupling have …


Novel Ox40 And 4–1bb Derived Spacers Enhance Cd30 Car Activity And Safety In Cd30 Positive Lymphoma Models, Lindsay Kua, Chee Hoe Ng, Jin Wei Tan, Hwee Ching Tan, Cheah Chen Seh, Fiona Wong, Richard Ong, Cliona M Rooney, Joel Tan, Qingfeng Chen, Ivan D Horak, Kar Wai Tan, Lionel Low Oct 2024

Novel Ox40 And 4–1bb Derived Spacers Enhance Cd30 Car Activity And Safety In Cd30 Positive Lymphoma Models, Lindsay Kua, Chee Hoe Ng, Jin Wei Tan, Hwee Ching Tan, Cheah Chen Seh, Fiona Wong, Richard Ong, Cliona M Rooney, Joel Tan, Qingfeng Chen, Ivan D Horak, Kar Wai Tan, Lionel Low

Faculty, Staff and Students Publications

The chimeric antigen receptor (CAR) derived from the CD30 specific murine antibody, HRS-3, has produced promising clinical efficacy with a favorable safety profile in the treatment of relapsed or refractory CD30-positive lymphomas. However, persistence of the autologous CAR-T cells was brief, and many patients relapsed a year after treatment. The lack of persistence may be attributed to the use of a wild-type immunoglobulin (Ig)G1 spacer that can associate with Fc receptors. We first identified the cysteine-rich domain (CRD) 5 of CD30 as the primary binding epitope of HRS-3 and armed with this insight, attempted to improve the HRS-3 CAR functionality …


Applicative Recursion And Nominal Licensing, Yining Nie Oct 2024

Applicative Recursion And Nominal Licensing, Yining Nie

Faculty Research, Scholarly, and Creative Activity

Languages with applicative morphology vary in whether their applied arguments can stack, or “recurse.” Focusing primarily on Bantu languages, I argue that the availability of applicative recursion in a given language depends on abstract nominal licensing ⎯in particular, on whether the applicative heads responsible for introducing applied arguments are nominal licensers. Applicative recursion therefore provides a novel diagnostic for the presence of abstract nominal licensing, which is argued to be driven not by Case but by ϕ-feature checking. The proposed approach to applicative recursion provides evidence for the role of abstract licensing in Bantu languages and has implications for approaches …


Teachers’ Perceptions Of An Integrated Nutrition Education Curriculum And The Impact On Preschoolers' Food Liking, Alicia Stapp, Laurel Lambert, Georgianna Mann, Kaitlyn Sills, Kenya Wolff Oct 2024

Teachers’ Perceptions Of An Integrated Nutrition Education Curriculum And The Impact On Preschoolers' Food Liking, Alicia Stapp, Laurel Lambert, Georgianna Mann, Kaitlyn Sills, Kenya Wolff

Journal of Public Health in the Deep South

Background: Nutrition education during early childhood that includes experiential learning, modeling, and family engagement can support lifelong healthy eating habits.

Purpose: The present study examined the impact of a nutrition-integrated, 32-week supplemental curriculum entitled Growing Healthy Minds, Bodies, and Communities on children’s exposure to fruits and vegetables, ability to identify fruits and vegetables, liking of fruit and vegetables, and teachers’ perceptions of the curriculum.

Methods: A pre- and post- fruit and vegetable pictorial Likert survey was administered to 261 Pre-K4 children. To investigate teachers’ perceptions of the curriculum, a post-intervention focus group was conducted with 19 teachers.

Results: Significant differences …