Digital Commons Network^™

Effect Of Voltage-Dependent Potassium Channel Antagonism On Vasodilation In Skeletal Muscle Of Humans, Ysabella I. Ruiz-Pick, Rauchelle E. Richey, Brenda L. Gilliland, Tyson C. Garfield, Asim Kichloo, Albert H. Olivencia-Yurvati, Gregory M. Dick, Steven A. Romero

International Journal of Exercise Science: Conference Proceedings

Vascular smooth muscle cells in resistance arterioles express a diverse array of ion channels that control microvascular function. Specifically, voltage-dependent potassium (K_V) channels induce vasodilation via smooth muscle hyperpolarization, positioning these channels as important regulators of vascular tone, and thus blood flow. PURPOSE: Despite substantial research exploring the influence of K_V channels in the regulation of blood flow in various animal models, many aspects of their regulation remain incompletely understood in humans. Specifically, this relationship has never been explored in human skeletal muscle in vivo, the major site of total peripheral resistance. Therefore, we tested …

“Phytochemical Analysis, In Vitro Anti-Oxidant, Anti-Diabetic And Anti-Inflammatory Activity Of Red Kidney Bean (Phaseolus Vulgaris L.) ”, Nancy Mani, D Annette Beatrice, R Durga Priyadarshini

International Journal of Health and Allied Sciences

Aims: The aim of the study is to assess the phytochemicals, bioactive compounds and determine the in vitro anti-oxidant, anti-diabetic and anti-inflammatory potential of red kidney bean.

Methods and Material: Raw and cooked red kidney bean (Phaseolus vulgaris. L) were assessed for phytochemical content, anti-oxidant, anti-diabetic and anti-inflammatory activity and GC-MS analysis was done to identify the bioactive compounds.

Statistical analysis used: Descriptive statistics, independent ‘t’ test and one-way ANOVA was computed to determine the differences in the phytochemical compounds and in vitro activities of raw and cooked red kidney beans.

Results: Qualitative analysis of raw and …

The Current Situation , Challenges And Responses To Hidden Hunger Among Chinese Residents, Liu Rui, Huang Jiazhang, Miao Yiyuan, Sun Junmao, Sheng Jiping, Wang Zhihong, Yin Shutao, Yu Huanling, Nie Ying

Food and Machinery

The problem of hidden hunger is a common challenge facing the world.In recent years,China has actively responded to the problem of hidden hunger,and the problem of hidden hunger has been significantly improved.The article summarizes the concept and connotation of hidden hunger,the current situation of hidden hunger in various countries around the world,the important measures and achievements of China in dealing with hidden hunger,and the challenges still facing,and puts forward suggestions on countermeasures in the future,aiming at better promoting the realization of nutrition and health for all people and common prosperity.

Detection Of Allergen Mango Components By Using Droplet Digital Pcr Technology, Li Enjing, Wang Dan, Li Long, Li Hejing, Yang Honglian

Food and Machinery

［［Objective ］］ A droplet digital PCR method for detect allergen mango components was established in this study.[Methods ] Firstly,the chloroplast trnH-psbA gene was selected as the target gene for detect allergen mango components.Secondly,specific primers and probe were designed.Finally,the reaction conditions of droplet digital PCR was optimized to verify the sensitivity and stability of the method.[Results ] This method had been applied to detect allergen mango components in 10 batches of food samples.The results of establishment of droplet digital PCR method was showed good specificity and not cross -react with 10 kinds of other fruits except mango.Under the optimal ddPCR reaction …

Online Simultaneous Determination Of Lactoferrin And Immunoglobulin G In Dairy Products By Two-Dimensional Liquid Chromatography, Chen Qin, Zhou Langjun, Chen Zijing, Liu Mengni, Lin Senyu

Food and Machinery

［［Objective ］］ A method of two -dimensional liquid chromatograohy was established to simultaneously determine the content of lactoferrin and immunoglobulin G in dairy products.[Methods ] The pretreated samples were directly injected into the constructed system.Target protein and other effects were separated on a Pharmacia HI -Trap Protein G as the first -dimensional column using a mobile phase consisting of sodium phosphate buffer and glycocoll buffer by gradient elution lactoferrin and immunoglobulin G were separated on a BioCore SEC -300 (4.6 mm ×250 mm,5 μm) as the second -dimensional column using a mobile phase consisting of water and sodium phosphate buffer …

The Effect Of Ultrafine Tianma Powder On The Behavior Of Motion Sickness Model Mice, Zhu Hongri, Li Jianxiang, Wang Zhaojun, Chen Yonghong

Food and Machinery

［［Objective ］］ To solve the problem of adverse side effects of anti -vertigo drugs and to develop functional foods with the same source of medicine and food as anti -motion sickness.［［Methods ］］ After 7 days of adaptive feeding,50 mice were divided into normal group,model group,positive drug group,Gastrodia H group and Gastrodia L group,and the mouse motion sickness model was constructed by rotational stimulation method,and the ultrafine powder of Gastrodia (gastrodin content 1.05%) was administered by gavage,and the treatment effect of Gastrodia on motion sickness model mice was evaluated by behavioral indicators such as motion sickness reaction index,balance beam test and …

Determination Of Chlorothalonil And Its Metabolite 4-Hydroxychlorothalonil Residues In Animal-Derived Food By Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry, Liu Xiaofang, Li Zheng, He Hao, Jiang Junjie, Chen Yuanyuan

Food and Machinery

［［Objective ］］ To establish a method for simultaneous determination of chlorothalonil and its metabolite 4-hydroxychlorothalonil residues in animal -derived food by ultra -high performance liquid chromatography -tandem mass spectrometry.［［Methods ］］ The samples were extracted by oscillating with acetonitrile solution of 1% acetic acid,defatted with n -hexane,purified by matrix dispersible solid phase extractant (PSA,anhydrous magnesium sulfate ),separated by Waters BEH C18 column under a gradient elution program using 0.1% formic acid aqueous solution and acetonitrile as the mobile phases.The anion multiple reaction monitoring model (MRM ) of atmospheric pressure chemical ionization source (APCI ) was used for the determination,and the matrix …

Effect Of Chicory Polysaccharide On The Texture And Storage Quality Of Round Scad Fish Ball, Xue Shan, Lin Jingjuan

Food and Machinery

［［Objective ］］ The processing technology of round scad (Decapterus maruadsi) fish balls with chicory polysaccharide was optimized and its storage characteristics were analyzed.[Methods ] The effects of chicory polysaccharide (CP) supplemental level,corn starch supplemental level,salt supplemental level,water supplemental level,complex phosphate supplemental level and gel temperature on the texture and comprehensive score of scad fish balls were investigated.The processing technology of chicory polysaccharide scad fish balls was optimized based on the comprehensive score.The processing technology of chicory polysaccharide scad fish balls was optimized based on the comprehensive score.The microstructure of the fish balls was observed by optical microscope and scanning electron …

Research Progress Of Near Infrared Spectroscopy In Condiments Detection, Yu Xinlei, Zhang Jiahui, Liu Taiang, Yin Mingyu, Wang Xichang

Food and Machinery

The traditional detection methods for condiments have the disadvantages of time -consuming,high cost and destructive detection,while the near infrared spectroscopy （NIRS ）is a fast,accurate,nondestructive and convenient method,which has been used in condiment industry.With the development of chemometrics,electronic information technology and instrumentation hardware,the near infrared spectroscopy is increasingly improved.This review expounds the classification and common detection methods of condiments,and summarizes the principle,characteristics and rapid detection model of NIRS.The principle,characteristics and rapid detection model of NIRS are outlined.The research progress of near infrared spectroscopy in condiment in recent years is reviewed,including ingredient detection,adulteration identification,brand traceability and quality detection.In addition,the development trend of …

Research Progress On Digestion , Absorption And Health Efficacy Of Astaxanthin Ester, Du Yufeng, Che Hongxia, Li Xiaoran, Zhou Miaomiao, Hou Peng

Food and Machinery

Astaxanthin is primarily found in both free and esterified forms in nature,With astaxanthin esters presenting various structural variations.These forms differ significantly in their digestive,absorption,and health -related functions compared to free astaxanthin.This review provides a comprehensive overview of the latest research regarding the sources,digestion and absorption characteristics,and health benefits of astaxanthin esters,based on an analysis of domestic and international studies.It examines how the presence of fatty acids affects the digestion and absorption of astaxanthin ester and discusses their functional activity and potential mechanisms.Additionally,the review highlights existing challenges in the development and utilization of astaxanthin esters.

Research Progress Of Plant Extracts In Preservation Of Meat Products, Li Hongyan, Xu Minglei, Zhai Saiya

Food and Machinery

Plant extracts contain natural active ingredients,offering benefits such as health,ecofriendliness,and sustainability.Traditional chemical preservatives,however,can contribute to environmental pollution and pose health risks,limiting their suitability for long -term use.This underscores the need for natural,eco-friendly preservative solutions..Plant polyphenols and essential oil are the primary plant -derived compounds currently applied in the meat industry,valued for their antioxidant and antibacterial properties.These compounds show promise as natural preservatives,potentially replacing chemical options while preserving the sensory quality and extending the shelf life of meat products.In addition to ensuring food safety and supporting essential processing qualities,plant extracts help preserve the sensory attributes of meat products,thereby extending shelf life.This …

Determination Of Tetraniliprole Residues In Animal Derived Foods By Multi-Plug Filtration Cleanup Combined With Hplc-Ms/Ms, Yuan Liejiang, Wang Xiu, Li Zheng, Zhu Li, Deng Hang

Food and Machinery

［［Objective ］］ This study aimed to develop a rapid and efficient method for quantifying tetraniliprole residues in animal -derived foods by combining multi -plug filtration cleanup (m-PFC ) with high -performance liquid chromatography -mass spectrometry (HPLC -MS).［［Methods ］］ Samples were extracted with acetonitrile,followed by salting out using sodium chloride and anhydrous magnesium sulfate.The extracts were purified via m -PFC and analyzed using HPLC -MS with external standard calibration.［［Results］］ The method demonstrated a strong linear correlation between tetraniliprole concentration and response values over a range of 0.001 to 0.150 mg/L,with a coefficient of determination (R2) exceeding 0.999.The limit of quantification (LOQ …

Research Progress On Different Pickling Techniques And Their Equipment Applications, Dong Junyi, Yao Huanli, Chen Shuai, Lu Jing, Xu Zeyu

Food and Machinery

The traditional pickling method for meat has a slow pickling speed and uneven pickling solution,which can easily lead to unstable taste and color of the meat.With the deepening of research in recent years,the improvement mechanism of new technologies such as ultra -high voltage and pulsed electric field on the quality of meat pickling has gradually been elucidated and applied in meat pickling.The article reviews the research progress of different pickling techniques and their equipment applications,including ultrasonic pickling technology,vacuum rolling pickling technology,variable pressure rolling pickling technology,ultra -high pressure pickling technology,and pulse electric field technology.The advantages and disadvantages of these techniques and …

Effects Of The Conditions Of Frozen Storage And Freeze-Thaw Treatment On The Formation Of Α-Dicarbonyl Compounds In Unwashed Silver Carp Surimi, Su Jie, Li Jiayi, Liu Yongle, Zhou Jinsong, Huang Yiqun, Li Xianghong, Wang Faxiang

Food and Machinery

［Objective］ To regulate the formation of α-dicarbonyl compounds (α-DCs ) in unwashed silver carp surimi.［Methods］ The levels of 3-deoxyglucosaldosterone (3-DG),glyoxal (GO),pyroacetal (MGO ) and 2,3-butanedione (2,3-BD) were analyzed in surimi during frozen storage and freeze -thaw cycles at -18 ℃ and -60 ℃.The effects of freezing temperature,freezing method,and the addition of an antifreeze agent (enzymatic hydrolysis product of silver carp ) on the formation of these α-DCs were evaluated.［Results］］ After 60 days of storage at -60 ℃,the levels of 3-DG,MGO and 2,3-BD increased by 209%,122% and 139%,respectively,but were significantly lower compared to storage at -18 ℃.GO levels initially increased,peaking on …

Nondestructive Detection Of Chilled Mutton Ph Value Using Hyperspectral Imaging Technique, Li Mengyuan, Zhang Wenguang, Jiang Xinhua, Xu Ziyang, Shi Caixia

Food and Machinery

［Objective］ To detect the pH value of chilled mutton quickly and non -destructively.［Methods］ Visible/near -infrared hyperspectral (400~1 000 nm) imaging technology was used to collect scattering images on the surface of chilled mutton,and the reflectance spectral curve of the region of interest of the sample was extracted to obtain the original spectral data.Four single methods of savitzky -golay (SG),multiplicative scatter correction (MSC ),standard normal variant transformation (SNV ) and first -order derivative (FD) and three combination methods of MSC -SG,SNV -SG and FD -SG were used to preprocess the original spectral data.Linear regression model:partial least squares regression (PLSR ) and …

The Improving Effects Of Probiotic Fermented Tomato Juice Combined With High-Intensity Interval Training On Diabetic Cardiomyopathy In Mice, Li Yahui

Food and Machinery

［Objective］ Seeking a comprehensive therapeutic approach to address multiple pathological processes in Diabetic Cardiomyopathy (DCM ).［Methods］ Randomly divided all mice into control group,DCM group,DCM +PFTJ group,DCM +HIIT group,and DCM +PFTJ +HIIT group.Used intraperitoneal injection of streptozotocin combined with high -fat diet to treat mice,and treated them according to the experimental plan for 16 weeks.Recorded the heart weight to body weight ratio (HW/BW ),detected cardiac function using small animal ultrasound imaging system,and assessed the pathological damage of the heart by detecting the levels of lactate dehydrogenase (LDH ),creatine kinase (CK),troponin I,IL-6,IL-1β,and TNF -α in the serum,combined with hematoxylin and eosin staining.At …

Study On The Detection Of Tetracycline By Electrochemical Sensors Modified With Nanomaterials, Wang Chenyu, Li Xiaoran, Quan Ke, Liu Miao, Wang Jianhui, Chen Qijie, Zhang Bo

Food and Machinery

Tetracycline (TC) is a typical broad -spectrum antibiotic with extensive applications in fields such as food and medicine.However,its improper use can pose a threat to human health and environmental safety.Therefore,detecting the residue of tetracycline is very important.In recent years,electrochemical sensors modified with nanomaterials have been successfully applied for the detection of tetracycline residues in food and environmental samples due to their high sensitivity and fast response.This review compares the electrochemical sensors modified with different nanomaterials for tetracycline detection,aiming to provide a reference for trace analysis of tetracycline and the development of more efficient detection technology.At the same time,this review also …

Enzymatic Hydrolysates Of Mulberry Leaf Flavonoids Alleviate Depression Induced By Reserpine In Zebrafish, Zheng Xuan, Lu Yunke, Zhou Chunling, Zhang Ju, Wang Mingxue, Cui Shizhan, Jia Dongsheng

Food and Machinery

［Objective］ This study aims to investigate the anti -depression effects of enzymatic hydrolysates of mulberry leaf flavonoids (EMLF ).［Methods］ EMLF was prepared and its components were analyzed by UPLC -MS.A zebrafish model of depression was induced by 40 mg/L reserpine.Six groups were designed,including the control,model,fluoxetine,L-EMLF (20 μg/mL ),M-EMLF (40 μg/mL ),and H-EMLF (80 μg/mL ) groups.Behavioral tests,including the new tank test and the light -dark box test,were conducted.The structural changes in the brain tissue of zebrafish in each group were observed by HE staining.The mRNA levels of interleukin -1β (IL-1β),tumor necrosis factor -α (TNF-α),tryptophan hydroxylase -2 (TPH- 2),and 5-hydroxytryptamine 2A …

Study On The Physicochemical Properties And Antioxidant Capacity Of Fish Maw Digestive Juices From Pangasianodon Hypophthalmus, Feng Rui, Huang Darong, Zhong Biluan, Zhang Yu, Liang Jiehua, Tang Xiaoshu, Chen Xuemei, Tian Jianxin

Food and Machinery

［Objective］ This study aimed to investigate the impact of digestion time on the digestibility,physicochemical properties,and antioxidant activity of Pangasianodon hypophthalmus fish maw.［Methods］ In vitro digestion was performed with simulated gastric fluid and simulated small intestine fluid.The relative molecular weight,Zeta potential and amino acid composition of the digestive fluid were determined by gel permeation chromatography (GPC ),amino acid analyzer and Zeta potentiometer,and the antioxidant capacity of the digestive fluid was evaluated.［Results］］ After the combined treatment of 1.5 h gastric fluid digestion and 4 h small intestinal fluid digestion,the digestibility,i.e.the total ratio of oligopeptide and polypeptide content,the total amino acid and the …

Optimization Of Processing Technology Of Dali Ginseng And Analysis On Its Anti-Oxidation Activity, Li Genyue, Wang Yudan, Yang Kaili, Han Lusheng, Wang Enpeng

Food and Machinery

［Objective］ This study aimed to determine the optimal processing conditions for Dali ginseng (DG) and evaluate its antioxidant activity.［Methods］ Total ginsenosides content in DG was measured under different liquid -material ratios,temperatures,and extraction time.The response surface method was employed to optimize the processing conditions.UPLC -QQQ -MS was used to analyze the ginsenoside content,and the antioxidant activity of DG extracts with different polarities was evaluated using various antioxidant indexes.［Results］］ The optimal processing conditions of DG were processing at 95 ℃ with liquid -solid ratio 22∶1 (mL/g ) for 30 mins.Under the control of these conditions,the maximum content of total ginsenosides at 3.75% …

Impact Of Voluntary Exercise On Systemic Inflammation In A 2? Hit Model Of Heart Failure With Preserved Ejection Fraction, Heather Quiriarte, Eunhan Cho, Youyoung Kim, Jake E. Doiron, Gregory Davis, James Stampley, Robert C. Noland, Zhen Li, Sanjiv J. Shah, Brian A. Irving, Guillaume Spielmann, David J. Lefer, Timothy D. Allerton

Faculty Publications

No abstract provided.

Minutes, Curriculum Committee Meeting, Tuesday, February 18, 2025, Curriculum Committee

Curriculum Committee Minutes

No abstract provided.

Crème De La Conference: 8th World Congress Of Pediatric Cardiology And Cardiac Surgery-Wcpccs 2023, Carissa M. Baker-Smith, Liesl Zühlke, Jennifer Co-Vu, Shubhika Srivastava, Renelle George, Shelby Kutty, Ali N. Zaidi, David J. Goldberg, Erica D. Sood, Kathryn M. Dodds, David S. Cooper, Mitchel I. Cohen, Gil Wernovsky, Jeffrey P. Jacobs

Department of Medicine Faculty Papers

No abstract provided.

Automated And Assisted Identification Of Stroke Using Feature-Based Brain Imaging, Karl A. Kasischke, William Scott Burgin

USF Patents

Provided herein are systems and methods for automated identification of volumes of interest in volumetric brain images using artificial intelligence (AI) enhanced imaging to diagnose and treat acute stroke. The methods can include receiving image data of a brain having header data and voxel values that represent an interruption in blood supply of the brain when imaged, extracting the header data from the image data, populating an array of cells with the voxel values, applying a segmenting analysis to the array to generate a segmented array, applying a morphological neighborhood analysis to the segmented array to generate a features relationship …

Biguanides Antithetically Regulate Tumor Properties By The Dose-Dependent Mitochondrial Reprogramming-Driven C-Src Pathway, Jun Hyoung Park, Kwang Hwa Jung, Dongya Jia, Sukjin Yang, Kuldeep S Attri, Songyeon Ahn, Divya Murthy, Tagari Samanta, Debasmita Dutta, Meron Ghidey, Somik Chatterjee, Seung Yeop Han, Diego A Pedroza, Abha Tiwari, Joyce V Lee, Caitlin Davis, Shuting Li, Vasanta Putluri, Chad J Creighton, Nagireddy Putluri, Lacey E Dobrolecki, Michael T Lewis, Jeffrey M Rosen, José N Onuchic, Andrei Goga, Benny Abraham Kaipparettu

Faculty, Staff and Students Publications

The biguanide metformin attenuates mitochondrial oxidation and is proposed as an anti-cancer therapy. However, recent clinical studies suggest increased proliferation and fatty acid β-oxidation (FAO) in a subgroup of patients with breast cancer (BC) after metformin therapy. Considering that FAO can activate Src kinase in aggressive triple-negative BC (TNBC), we postulate that low-dose biguanide-driven AMPK-ACC-FAO signaling may activate the Src pathway in TNBC. The low bioavailability of metformin in TNBC xenografts mimics metformin's in vitro low-dose effect. Pharmacological or genetic inhibition of FAO significantly enhances the anti-tumor properties of biguanides. Lower doses of biguanides induce and higher doses suppress Src …

Paradigm Shift In Obesity Treatment: An Extensive Review Of Current Pipeline Agents, Ecesu Çeti̇n, Brian Pedersen, Mehmet Furkan Burak

Turkish Journal of Medical Sciences

Obesity is a multifaceted disease that poses a significant public health challenge. Recent discoveries in understanding the biological pathways that regulate satiety and metabolism have led to a shift in the treatment paradigm for obesity. Thus, the gap between pharmacological and surgical interventions has diminished. The latest approved anti-obesity medications are achieving weight loss comparable to surgery. These GLP-1 analog-based therapies not only cause substantial weight loss but also improve obesity-associated comorbidities. However, there are still unmet needs in obesity care, and treatment options with alternative pathways are necessary. Whether achieved through lifestyle changes or medication, weight loss often leads …

Synthetic Osteobiologics In Spine Surgery: A Review, Aydin Si̇nan Apaydin, Eli Johnson, Prince Antwi, Brett Rocos, Michael M. Haglund, Christopher Shaffrey, Peter Passias, Muhammad Adb-El-Barr, Khoi Than

Turkish Journal of Medical Sciences

Background/aimOsteobiologics are increasingly used in orthopedics and spine surgery to facilitate bone healing and prevent non-union. Synthetic osteobiologics are artificial materials crafted in laboratories that aim to replicate the natural composition and functionality of bone. Notable examples, such as calcium phosphate and calcium sulfate, are engineered to mirror the mineral aspect of bone. They mimic human bone functionality, exhibiting osteoconductive, osteoinductive, and osteogenic properties. These characteristics promote cell attachment, migration, recruitment, and differentiation. Consequently, synthetic osteobiologics (osteoconductive grafts) have been introduced in bone fracture repair. The main strength of synthetic osteobiologics in spine surgery lies in improving fusion rates and …

Empagliflozin Effects On Cyclophosphamide-Induced Neurotoxicity In Rats Without Diabetes, Şeri̇fe Ezgi̇ Doğan, Şeri̇fe Mehli̇ka Kuşkonmaz, Pinar Celepli̇, Mehmet Şenes, Sema Hücümenoğlu, Cavi̇t Çulha

Turkish Journal of Medical Sciences

Background/aim: The objective of this study is to evaluate the effect of empagliflozin on cyclophosphamide-induced neurotoxicity in rats.Materials and methods: A total of 32 male Wistar rats were separated into 4 groups as 8 rats each: control group, cyclophosphamide group, empagliflozin group and the cyclophosphamide plus empagliflozin group. At the end of the experiment rats' brains were removed for biochemical analysis of oxidative stress parameters (malondialdehyde, total sulfhydryl, total oxidant status and total antioxidant capacity) and histopathological analysis.Results: Total sulfhydryl levels were increased in group empagliflozin and group empagliflozin and cyclophosphamide compared to the cyclophosphamide group but did not improve …

Relationship Between The Density Of Degenerated Neurons In The Carotid Body And Changes In Blood Ph, Hakan Kina, Aydin Si̇nan Apaydin

Turkish Journal of Medical Sciences

Background/aimCarotid artery is the majority artery for brain feeding. Carotid Bodies (CBs) are located in carotid bifurcation and regulate body fluid pH. We aimed to evaluate the changes in CB-related pH levels as a consequence of degeneration induced by the ligation of both Common Carotid Arteries (BCCAL).Materials and methodsWe included 23 adult male New Zealand rabbits. A control group (n= 5); a sham group (0.5 mL saline injected n=5) and the main study group (subjected to the BCCAL procedure, n = 13). We monitored and recorded pH levels, and cardiac rhythms before, during, and after the experiments at two-day intervals. …

The Abdominal Compliance Index And Postoperative Pain After Laparoscopic Gynecologic Surgery: A Preliminary Observational Cohort Study, Ebru Akgün Şarer, Mustafa Tahtaci, Umut Cahi̇t Ersoy, Mehtap Honca

Turkish Journal of Medical Sciences

Background/aimLaparoscopic surgery in gynecology has advantages of reduced scarring, less postoperative pain, faster recovery and lower risk of complications. Despite these adavantages, shoulder pain still remains a major concern affecting upto 90% of patients undergoing gynecologic laparoscopic surgery. The use of Abdominal compliance index (ACI) may offer the benefits of gaining work space for safer surgery and may prevent the drawbacks of applying higher insuflation pressures.We investigated the relation of shoulder pain and abdominal pain and analgesic use with the recently advised ACI which is a surrogate index of abdominal expansion in patients undergoing gynecologic laparoscopic surgery.Materials and methodsThirty one …