Digital Commons Network^™

Unmasking Online Hostility: Analysing And Mitigating Hate Speech In Social Media, Jawaid Ahmed Siddiqui, Siti Sophiayati Yuhaniz, Zulfiqar Ali Memon

Baghdad Science Journal

The social media platforms have been generating an enormous amount of data for every second. Twitter, in practice by the individuals is producing more than six hundred tweets in each second. While freely posting opinions and expressions by users, it is very difficult to confine the hate speech shared against any individual, religion or any ethnic group. Consequently, the persons targeted by such hateful content get frustrated. In this regard the different approaches have been solving this serious problem but, sometimes unable to achieve satisfactory results. Therefore, we propose different Machine Learning models to classify given data in two categories, …

Design And Structural Basis Of Selective 1,4-Dihydropyridine Inhibitors Of The Calcium-Activated Potassium Channel KCa3.1, Seow Theng Ong, Young-Woo Nam, Joshua A. Nasburg, Alena Ramanishka, Xuan Rui Ng, Zhong Zhuang, Stephanie Shee Min Goay, Hai M. Nguyen, Latika Singh, Vikrant Singh, Alicia Rivera, M. Elaine Eyster, Yang Xu, Seth L. Alper, Heike Wulff, Miao Zhang, K. George Chandy

Pharmacy Faculty Articles and Research

The 1,4-dihydropyridines, drugs with well-established bioavailability and toxicity profiles, have proven efficacy in treating human hypertension, peripheral vascular disorders, and coronary artery disease. Every 1,4-dihydropyridine in clinical use blocks L-type voltage-gated calcium channels. We now report our development, using selective optimization of a side activity (SOSA), of a class of 1,4-dihydropyridines that selectively and potently inhibit the intermediate-conductance calcium-activated K+ channel K_Ca3.1, a validated therapeutic target for diseases affecting many organ systems. One of these 1,4-dihydropyridines, DHP-103, blocked K_Ca3.1 with an IC50 of 6 nM and exhibited exquisite selectivity over calcium channels and a panel of …

Sesame Street: From Puppets To Pixels, Blaise C. Wingold

Departmental Honors & Graduate Capstone Projects

Sesame Street has been around since 1969 and is still creating new episodes. Joan Ganz Cooney created the program in an attempt to use television to educate and entertain children simultaneously. The show set out goals to create smarter, kinder, and stronger kids. It uniquely featured a diverse cast and was targeted towards disadvantaged youth. However, the world has changed a lot since 1969. In this research, I use a qualitative content analysis to determine how exactly the show has evolved and adapted to target today’s children versus the children in 1969. Additionally, the paper hypothesizes reasons why the show …

Remaking Rulemaking: Lessons From The History Of Federal Rule Of Civil Procedure 54(B), Brad Baranowski, Emery G. Lee Iii

Cleveland State Law Review

This Article uses the lost history of Federal Rule of Civil Procedure 54(b) to provide a framework for rulemaking at the busy intersection of complex litigation and appellate finality. The drafters of the original civil rules spent more time thinking through how to efficiently combine claims and parties in civil actions—a promised benefit of the proposed law-equity merger—than about how combined claims should be dis-assembled. This failure would haunt the original Advisory Committee on Civil Rules for years. Nowhere was this more evident than in the first decades of Rule 54(b)’s existence.

Promulgated in 1938, Rule 54(b) was designed to …

Enhancing Skin Cancer Literacy Amongst Young Adults: A Digital Design, Katherine Stoll

Honors Projects

The skin plays a vital role in protection, regulation, and homeostasis of the human body. Skin cancer, despite being mostly preventable, is one of the most common cancers. Young adults, ages 18 to 25, are vulnerable targets due to risky behaviors and misinformation regarding skin cancer. This project was designed by using digital media and website design to enhance skin cancer health literacy among young adults. Using a systematic literature review and research methods, an interactive website was designed to improve skin cancer health literacy and eliminate common misconceptions. The topics addressed throughout the website were the biological factors of …

Daddy’S Little Girl: The Role Of Life History In Paternal Investment Towards Daughters, Ray Garza, Emily Woolman, Sepide Pazhouhi, Farid Pazhoohi

School of Psychology

ObjectivesThis study examines the complex dynamics of father-daughter relationships, focusing on how life history factors are associated with paternal behaviors towards daughters. Drawing on Life history Theory and the Daughter-Guarding hypothesis, the research investigates how these factors contribute to father-daughter interactions, such as attachment, protection, support, and control received from fathers.MethodsTwo surveys were conducted: one with 120 daughters aged 18–21 (Study 1) and another with 120 fathers (Study 2), both recruited through online platforms. Study 1 examined the relationship from the daughters’ perspective, while Study 2 explored it from the fathers’ perspective.ResultsFathers with higher education and stable financial backgrounds showed …

Crow's Nest, April 28, 2025, Crow's Nest Staff

Crow's Nest

No abstract provided.

Digital Discourse On Alzheimer’S Disease: A Text Analysis Of Crosscultural Sentiments In Online Communities, Maryam Imran

Harriet L Wilkes Honors College Theses 2020 - Present

Alzheimer’s disease is a neurological condition characterized by a significant decline in cognitive function. Due to its severe effects and the absence of a cure, early diagnosis and treatment are crucial for slowing its progression. My project examines how cultural perceptions of Alzheimer’s disease are reflected in digital discourse. Using Voyant, a text analysis tool, and the NRC Emotion Lexicon, I analyzed Reddit discussions from South Asian, East Asian, and North American individuals, categorizing their posts into three themes: diagnosis perceptions, treatment decisions, and family/social dynamics and classifying sentiments as negative, positive, or neutral to gain a deeper understanding of …

Chimes: April 28, 2025, Calvin University

Chimes

New native meadow breaks ground on Earth Day by Ian Tjoelker

Film students prepare for media showcase by Stella Stachowiak

Students premier original compositions at New Music at Calvin Concert by Graham Kort

Calvin responds to a national wave of visa revocations by Grace Buller

A dive into the world of the The Weather Belt by Ethan Meyers

Women's lacrosse falls to Hope in regular season finale, looks ahead to MIAA tournament by Zach Kern

Students unsure of effects of Calvin's Synod report by Clare Rybicki, McKenna Wilkinson & Sarah Sparling

Top of the Class: Beast Games meets Survivor at …

Task Demands Influence Search Strategy Selection In Otoconia-Deficient Mice, Ryan M. Yoder, Lucas C. Carstensen, Keshav Jagannathan

Psychology

Introduction: The vestibular system plays a crucial role in visual and non-visual navigation. Our recent study found that signals from the otolith organs are necessary for mice’s use of distal visual cues to guide navigation to an invisible goal. Somewhat surprisingly, however, performance was not significantly impaired on some spatial tasks (e.g., Barnes maze reference memory task), questioning the role of otolith signals in visual navigation.

Methods: We report the results of several additional tests of reference memory performance and search strategy use on two versions of the Barnes maze, in an attempt to establish further understanding of the otolithic …

The Role And Expression Of Pros-1 In The C. Elegans Gonad, Brandon W. Thomas, Mary B. Kroetz, Roberta Challener

Undergraduate Theses

The nematode, formally known as Caenorhabditis elegans, has served as an excellent model organism in understanding fundamental biological processes, including those governed by conserved genes like pros-1. pros-1 is partially responsible for the formation of tubular structures within the organism. Glial cells and excretory canals are both examples of tubular structures governed by pros-1. pros-1 orchestrates the embryonic development of these cell types by modulating cell proliferation and differentiation, thus ensuring proper morphogenesis and organogenesis. Its regulatory influence likely extends beyond embryogenesis, potentially affecting reproductive processes as well. Furthermore, the evolutionary conservation of pros-1 underscores its significance …

When Less Information Is Actually More: A Modest Proposal For Securities Reform, Daria Beshentseva

Seton Hall Law Review

No abstract provided.

Ultrasonography As A Method For Identifying Biological Sex In Captive Hellbenders (Cryptobranchus Alleganiensis), Logan N. Collom

Honors Theses

The hellbender (Cryptobranchus alleganiensis) is the United States’ largest aquatic salamander and is mainly found across the eastern U.S. There are two subspecies of hellbenders, one of which is listed as endangered by the US Fish and Wildlife Service and the other considered a species of conservation concern and a candidate for listing under the Endangered Species Act. There have been several captive breeding programs established at zoos and universities across the U.S., which require a dependable method for sexing their individuals. Ultrasound imaging has previously been used to identify the sex of other amphibian species and track …

"Nothing About Us Without Us": State-Level Disability Accommodation In The Wake Of The Ada, Megan F. Matteucci

Politics Honors Papers

The Americans with Disabilities Act (ADA) was passed in 1990 and protects people with disabilities (PWDs) from discrimination and includes provisions to make society more accommodating. The issue is that the ADA is federal legislation, but most of the implementation occurs at the state-level which means that some states are more accommodating than others. This project attempts to answer the following question: What factors contribute to the discrepancies in state-level disability policy and accommodation? It includes a quantitative study of all 50 states and investigates the impact of state income per capita, state partisanship, and business and disability interest group …

Variation In Bike Infrastructure Across American Cities, Jason D. Greenberg

Politics Honors Papers

What explains why some cities have developed extensive bike infrastructure while others have not? Bicycling is a low-cost transportation option and is becoming increasingly popular in the 21^st century. While there is extensive literature on bike infrastructure in the United States and its relationship with gentrification and advocacy, there is not significant, explicit dedication and focus toward explaining why variation exists across American cities. In my research design, I examine several factors that could point toward an explanation. The results show that policy diffusion is the most significant factor for bike infrastructure adoption, lending credence to prior literature on …

Congratulations, Library Graduates, University Of Dayton

University Libraries Blog Archive

The University Libraries held a ceremony on April 24 to celebrate student employees who will graduate in May or December 2025. Student employees are a vital part of the Libraries’ work and mission.

Edra 56: Bibliography, Tamara Karr

Bibliographies

EDRA 56: Designing Communities for Climate Action and Resilience

Determining The Bioaccumulation Of Minor Cannabinoids In Zebrafish Larvae, Kamdyn A. Holt

Honors Theses

Due to the increasing prevalence of cannabis product availability and usage in the modern United States, particularly among pregnant individuals, evaluating the bioaccumulation of minor cannabinoids to further understand the adverse effects of cannabinoids during early development is critical. This study quantitated the uptake of eight minor cannabinoids ((∆8-tetrahydrocannabinol (∆8-THC), ∆9-THC, ∆10-THC, cannabidiol (CBD), cannabigerol (CBG), cannabinol (CBN), tetrahydrocannabivarin (THCV), and hexahydrocannabinol (HHC)) in zebrafish larvae following water-borne 2 µM exposures from 6 to 96 hours post fertilization (hpf). Larvae were homogenized at 96 hpf and analyzed using a gas chromatography- mass spectrometry (GC-MS) method developed in this study. Bioconcentration …

Wound Ballistics With The Focus On Projectile Deformation, Nikita Khanov

D.U.Quark

Terminal ballistics, also called wound ballistics, is a field of ballistics that studies the projectile behaviour upon impact with a target. While the physical damage induced by the projectiles (typically bullets) and its medical treatment is well-researched, the deformation that the projectile itself undergoes is often underestimated in importance, and the research on this topic is lacking, although such changes can be a valuable source of forensic evidence. This review evaluates the deformation that occurs to non-fragmenting and various fragmenting bullets upon impact, as well as the effect that the body decomposition has on the bullets. The knowledge and understanding …

Fluorescent Labeling And Size-Dependent Uptake Of Mesoporous Silica Nanoparticles In Ovarian Cancer Tumor Spheroids, Kimberly R. Berardis

Honors Scholar Theses

Ovarian cancer is the most lethal gynecologic malignancy, with most patients presenting at an advanced stage. While surgical debulking improves survival, nonresectable tumors (<1 cm) contribute significantly to morbidity and remain difficult to treat. Nanocarrier-based drug delivery systems offer an innovative approach to targeted therapy and palliation. In vivo models have demonstrated that intraperitoneally delivered mesoporous silica nanoparticles (MSNs) preferentially accumulate in tumors with low systemic exposure, enabling targeted chemo- and radiotherapy.

MSNs are particularly suited for radiotherapeutic delivery, as their strong interactions with tumor extracellular matrices drive selective uptake. Additionally, they exhibit excellent stability under neutron flux, allowing for loading with stable isotopes and irradiation immediately prior to administration. High radionuclide retention after dilution further minimizes systemic exposure and toxicity.

A key …

Measuring Exposure Through Targeted Ads, Sarah Bazell

Honors Projects

This study investigates the effectiveness of targeted digital advertising strategies for Company X, a performance motorsports fuel brand. With the goal of optimizing engagement and improving budget allocation, four distinct ad campaigns were developed and tested on Facebook and Instagram: brand awareness, product education, dealer locator promotion, and lifestyle merchandise promotion. Each campaign was evaluated based on reach, impressions, cost per result, and conversion rates. Descriptive statistics revealed significant differences in engagement rates across campaigns, with video-based, emotionally driven ads outperforming static formats. A one-way ANOVA indicated no significant difference in reach across campaigns but confirmed significant differences in spending …

Yoder In Brooklyn? Rapidly Expanding Free Exercise Jurisprudence, New York State School Regulations, And Hasidic Yeshivas, Jonathan Acampora

Seton Hall Law Review

No abstract provided.

Humans Are Animals: A Review Of Animals Are People, Matthew R. Jamnik

The International Journal of Ecopsychology (IJE)

The Animals are People (AAP) story reflects a philosophical inquiry into the nature of sentience, what it means to cultivate community, and the ethical and moral considerations behind “sanctuary.”It gifts a heartwarming journey about growing up, rooting down, and falling in love with life. “We save the animals, then the animals save us,” and so the story goes.

Effects Of Acute Exercise On Cognition: Consideration Of Potential Moderators, Elizabeth G. Gaines, Mckenzie M. Cotten, Elizabeth Reese Carwile, Mary Griffin Jackson, Marascalco Liston, Lucy Wilson

Honors Theses

The present thesis aims to determine the effects, if any, of six potential moderators on the effects of acute moderate-intensity exercise on cognitive functioning. The modes of exercise undertaken by the participants included treadmill (Experiment 1) and stationary bike (Experiment 2) exercise. Participants in each experiment either exercised or rested for twenty minutes and then participated in either a memory recall task or cognitive functioning (“Stroop”) task. The bouts of either exercise or rest on the stationary bike were followed by a rest period during which the participant would be exposed to either standard air oxygen levels (normoxia) or hypoxic …

Silver Star: The Superheroine Love Of My Life, Primo C. Murillo Jr.

Master's Projects

Silver Star: The Superheroine Love of My Life is a new adult, queer romance novel about a pair of young women living in a modern world filled with superheroes. This manuscript covers the first five chapters of this proposed novel, which is still in development. The story follows Freddie Silang, a Filipina-American superhero fan with no superpowers, who struggles to find her place in life after college. Freddie's mundane life is forever changed, however, when she meets her favorite superhero, Ms. Metropolis, during a battle against a minor villain. After Freddie saves Ms. Metropolis in an impulsive, yet selfless act, …

The Potential Of Brain Organoids In Addressing The Heterogeneity Of Synucleinopathies, Xiao-Jun Diao, Claudio Soto, Fei Wang, Yu Wang, Yun-Cheng Wu, Abhisek Mukherjee

Faculty, Staff and Student Publications

Synucleinopathies are a group of diseases characterized by neuronal and glial accumulation of α-synuclein (aSyn) linked with different clinical presentations, including Parkinson's disease (PD), Parkinson's disease with dementia (PDD), Dementia with Lewy Bodies (DLB) and Multiple system atrophy (MSA). Interestingly, the structure of the aSyn aggregates can vary across different synucleinopathies. Currently, it is unclear how the aSyn protein can aggregate into diverse structures and affect distinct cell types and various brain regions, leading to different clinical symptoms. Recent advances in induced pluripotent stem cells (iPSCs)-based brain organoids (BOs) technology provide an unprecedented opportunity to define the etiology of synucleinopathies …

Investigative Needle Core Biopsies Support Multimodal Deep-Data Generation In Glioblastoma, Kenny K H Yu, Sreyashi Basu, Gerard Baquer, Ryuhjin Ahn, Jennifer Gantchev, Sonali Jindal, Michael S Regan, Zaki Abou-Mrad, Michael C Prabhu, Marc J Williams, Alicia D D'Souza, Seth W Malinowski, Kelsey Hopland, Yuval Elhanati, Sylwia A Stopka, Alexei Stortchevoi, Charles Couturier, Zhong He, Jingjing Sun, Yulong Chen, Alexsandra B Espejo, Kin Hoe Chow, Smitha Yerrum, Pei-Lun Kao, Brittany Parker Kerrigan, Lisa Norberg, Douglas Nielsen, Vinay K Puduvalli, Jason Huse, Rameen Beroukhim, Betty Y S Kim, Sangeeta Goswami, Adrienne Boire, Sarah Frisken, Michael J Cima, Matthias Holdhoff, Calixto-Hope G Lucas, Chetan Bettegowda, Stuart S Levine, Tejus A Bale, Cameron Brennan, David A Reardon, Frederick F Lang, E Antonio Chiocca, Keith L Ligon, Forest M White, Padmanee Sharma, Viviane Tabar, Nathalie Y R Agar

Faculty, Staff and Student Publications

Glioblastoma (GBM) is an aggressive primary brain cancer with few effective therapies. Stereotactic needle biopsies are routinely used for diagnosis; however, the feasibility and utility of investigative biopsies to monitor treatment response remains ill-defined. Here, we demonstrate the depth of data generation possible from routine stereotactic needle core biopsies and perform highly resolved multi-omics analyses, including single-cell RNA sequencing, spatial transcriptomics, metabolomics, proteomics, phosphoproteomics, T-cell clonotype analysis, and MHC Class I immunopeptidomics on standard biopsy tissue obtained intra-operatively. We also examine biopsies taken from different locations and provide a framework for measuring spatial and genomic heterogeneity. Finally, we investigate the …

Stability Analysis Of Excessive Carbon Dioxide Gas Emission Model Through Following Reforestation Policy In Low-Density Forest Biomass, Furqan Nezar, Shireen Jawad, Matthias Winter, Anwar Zeb

Baghdad Science Journal

Carbon dioxide is the main greenhouse gas contributing to global warming risk. Forest biomass is crucial for the sequestration of atmospheric carbon dioxide; however, the rate of decline in worldwide forest biomass is concerning and can be attributed to anthropogenic activities. Reforestation is essential in this situation to decrease the amount of C O₂ in the atmosphere. Efforts at reforestation can be evaluated according to the financial investment required for their execution. This work presents a nonlinear mathematical model that examines the impact of reforestation and the implementation of reforestation initiatives on regulating atmospheric CO₂ levels. The critical …

Fractal Dimension And Entropy Analysis Of Medical Images For Knn-Based Disease Classification, Krishna Mahapatra, Selvakumar R

Baghdad Science Journal

The study of medical image-based disease detection has witnessed a notable surge in interest and success with computational methods. This work proposes a novel framework to detect diseases at earlier stages from medical images, using mathematical model and Machine Learning. Introduce two new quantitative measures for COVID-19 and Tumor disease detection: image uncertainty based on Shannon entropy and image complexity based on fractal dimension. Our result demonstrated that in COVID-19 positive images exhibited skewed pixel distribution due to the hazy regions resulting in lower entropy values for diseased cases compared to healthy ones. The second quantity, fractal dimension was measured …

Facebook Comments-Based Assessment Model For Food Product Companies Using Four Machine Learning Methods With Arabic/Iraqi Lexicon, Raad Sadi Aziz, Sura Mazin Ali, Ahmed T. Sadiq

Baghdad Science Journal

People's need for food is increasing day after day due to the large population increase that has occurred in human society, which has led to a significant increase in the activity of food product manufacturing companies in the world. Hence the necessary need to evaluate the performance of food production companies. We found that the best way to evaluate the performance of these companies is through social media comments, because it is the newest and most common method among people. In this paper, 4 machine learning techniques were relied upon to evaluate participants' comments in evaluating food production companies after …