Digital Commons Network^™

Edra 56: Bibliography, Tamara Karr

Bibliographies

EDRA 56: Designing Communities for Climate Action and Resilience

Determining The Bioaccumulation Of Minor Cannabinoids In Zebrafish Larvae, Kamdyn A. Holt

Honors Theses

Due to the increasing prevalence of cannabis product availability and usage in the modern United States, particularly among pregnant individuals, evaluating the bioaccumulation of minor cannabinoids to further understand the adverse effects of cannabinoids during early development is critical. This study quantitated the uptake of eight minor cannabinoids ((∆8-tetrahydrocannabinol (∆8-THC), ∆9-THC, ∆10-THC, cannabidiol (CBD), cannabigerol (CBG), cannabinol (CBN), tetrahydrocannabivarin (THCV), and hexahydrocannabinol (HHC)) in zebrafish larvae following water-borne 2 µM exposures from 6 to 96 hours post fertilization (hpf). Larvae were homogenized at 96 hpf and analyzed using a gas chromatography- mass spectrometry (GC-MS) method developed in this study. Bioconcentration …

Wound Ballistics With The Focus On Projectile Deformation, Nikita Khanov

D.U.Quark

Terminal ballistics, also called wound ballistics, is a field of ballistics that studies the projectile behaviour upon impact with a target. While the physical damage induced by the projectiles (typically bullets) and its medical treatment is well-researched, the deformation that the projectile itself undergoes is often underestimated in importance, and the research on this topic is lacking, although such changes can be a valuable source of forensic evidence. This review evaluates the deformation that occurs to non-fragmenting and various fragmenting bullets upon impact, as well as the effect that the body decomposition has on the bullets. The knowledge and understanding …

Fluorescent Labeling And Size-Dependent Uptake Of Mesoporous Silica Nanoparticles In Ovarian Cancer Tumor Spheroids, Kimberly R. Berardis

Honors Scholar Theses

Ovarian cancer is the most lethal gynecologic malignancy, with most patients presenting at an advanced stage. While surgical debulking improves survival, nonresectable tumors (<1 cm) contribute significantly to morbidity and remain difficult to treat. Nanocarrier-based drug delivery systems offer an innovative approach to targeted therapy and palliation. In vivo models have demonstrated that intraperitoneally delivered mesoporous silica nanoparticles (MSNs) preferentially accumulate in tumors with low systemic exposure, enabling targeted chemo- and radiotherapy.

MSNs are particularly suited for radiotherapeutic delivery, as their strong interactions with tumor extracellular matrices drive selective uptake. Additionally, they exhibit excellent stability under neutron flux, allowing for loading with stable isotopes and irradiation immediately prior to administration. High radionuclide retention after dilution further minimizes systemic exposure and toxicity.

A key …

Measuring Exposure Through Targeted Ads, Sarah Bazell

Honors Projects

This study investigates the effectiveness of targeted digital advertising strategies for Company X, a performance motorsports fuel brand. With the goal of optimizing engagement and improving budget allocation, four distinct ad campaigns were developed and tested on Facebook and Instagram: brand awareness, product education, dealer locator promotion, and lifestyle merchandise promotion. Each campaign was evaluated based on reach, impressions, cost per result, and conversion rates. Descriptive statistics revealed significant differences in engagement rates across campaigns, with video-based, emotionally driven ads outperforming static formats. A one-way ANOVA indicated no significant difference in reach across campaigns but confirmed significant differences in spending …

Mine Closure Planning Must Face The Challenge Of Delivering Nature Positive Outcomes, Luis E. Sanchez, Angus Morrison-Saunders

Research outputs 2022 to 2026

The need to address and reverse global biodiversity decline is imperative across all of society including the practices of mine closure planning. Nature Positive is the latest global biodiversity-focused initiative which calls for at least 30% of biodiversity to be enhanced through effective restoration relative to the 2020 baseline. This paper conceptualizes and explains what is necessary in mine closure planning and implementation to meaningfully contribute to this and other nature-positive goals, with some illustrative examples. Issues considered include application of the mitigation hierarchy, rehabilitation in mining and the time lag challenge for restoring biodiversity, biodiversity offsetting, conserving nature while …

Yoder In Brooklyn? Rapidly Expanding Free Exercise Jurisprudence, New York State School Regulations, And Hasidic Yeshivas, Jonathan Acampora

Seton Hall Law Review

No abstract provided.

Humans Are Animals: A Review Of Animals Are People, Matthew R. Jamnik

The International Journal of Ecopsychology (IJE)

The Animals are People (AAP) story reflects a philosophical inquiry into the nature of sentience, what it means to cultivate community, and the ethical and moral considerations behind “sanctuary.”It gifts a heartwarming journey about growing up, rooting down, and falling in love with life. “We save the animals, then the animals save us,” and so the story goes.

Effects Of Acute Exercise On Cognition: Consideration Of Potential Moderators, Elizabeth G. Gaines, Mckenzie M. Cotten, Elizabeth Reese Carwile, Mary Griffin Jackson, Marascalco Liston, Lucy Wilson

Honors Theses

The present thesis aims to determine the effects, if any, of six potential moderators on the effects of acute moderate-intensity exercise on cognitive functioning. The modes of exercise undertaken by the participants included treadmill (Experiment 1) and stationary bike (Experiment 2) exercise. Participants in each experiment either exercised or rested for twenty minutes and then participated in either a memory recall task or cognitive functioning (“Stroop”) task. The bouts of either exercise or rest on the stationary bike were followed by a rest period during which the participant would be exposed to either standard air oxygen levels (normoxia) or hypoxic …

Silver Star: The Superheroine Love Of My Life, Primo C. Murillo Jr.

Master's Projects

Silver Star: The Superheroine Love of My Life is a new adult, queer romance novel about a pair of young women living in a modern world filled with superheroes. This manuscript covers the first five chapters of this proposed novel, which is still in development. The story follows Freddie Silang, a Filipina-American superhero fan with no superpowers, who struggles to find her place in life after college. Freddie's mundane life is forever changed, however, when she meets her favorite superhero, Ms. Metropolis, during a battle against a minor villain. After Freddie saves Ms. Metropolis in an impulsive, yet selfless act, …

The Potential Of Brain Organoids In Addressing The Heterogeneity Of Synucleinopathies, Xiao-Jun Diao, Claudio Soto, Fei Wang, Yu Wang, Yun-Cheng Wu, Abhisek Mukherjee

Faculty, Staff and Student Publications

Synucleinopathies are a group of diseases characterized by neuronal and glial accumulation of α-synuclein (aSyn) linked with different clinical presentations, including Parkinson's disease (PD), Parkinson's disease with dementia (PDD), Dementia with Lewy Bodies (DLB) and Multiple system atrophy (MSA). Interestingly, the structure of the aSyn aggregates can vary across different synucleinopathies. Currently, it is unclear how the aSyn protein can aggregate into diverse structures and affect distinct cell types and various brain regions, leading to different clinical symptoms. Recent advances in induced pluripotent stem cells (iPSCs)-based brain organoids (BOs) technology provide an unprecedented opportunity to define the etiology of synucleinopathies …

Investigative Needle Core Biopsies Support Multimodal Deep-Data Generation In Glioblastoma, Kenny K H Yu, Sreyashi Basu, Gerard Baquer, Ryuhjin Ahn, Jennifer Gantchev, Sonali Jindal, Michael S Regan, Zaki Abou-Mrad, Michael C Prabhu, Marc J Williams, Alicia D D'Souza, Seth W Malinowski, Kelsey Hopland, Yuval Elhanati, Sylwia A Stopka, Alexei Stortchevoi, Charles Couturier, Zhong He, Jingjing Sun, Yulong Chen, Alexsandra B Espejo, Kin Hoe Chow, Smitha Yerrum, Pei-Lun Kao, Brittany Parker Kerrigan, Lisa Norberg, Douglas Nielsen, Vinay K Puduvalli, Jason Huse, Rameen Beroukhim, Betty Y S Kim, Sangeeta Goswami, Adrienne Boire, Sarah Frisken, Michael J Cima, Matthias Holdhoff, Calixto-Hope G Lucas, Chetan Bettegowda, Stuart S Levine, Tejus A Bale, Cameron Brennan, David A Reardon, Frederick F Lang, E Antonio Chiocca, Keith L Ligon, Forest M White, Padmanee Sharma, Viviane Tabar, Nathalie Y R Agar

Faculty, Staff and Student Publications

Glioblastoma (GBM) is an aggressive primary brain cancer with few effective therapies. Stereotactic needle biopsies are routinely used for diagnosis; however, the feasibility and utility of investigative biopsies to monitor treatment response remains ill-defined. Here, we demonstrate the depth of data generation possible from routine stereotactic needle core biopsies and perform highly resolved multi-omics analyses, including single-cell RNA sequencing, spatial transcriptomics, metabolomics, proteomics, phosphoproteomics, T-cell clonotype analysis, and MHC Class I immunopeptidomics on standard biopsy tissue obtained intra-operatively. We also examine biopsies taken from different locations and provide a framework for measuring spatial and genomic heterogeneity. Finally, we investigate the …

Stability Analysis Of Excessive Carbon Dioxide Gas Emission Model Through Following Reforestation Policy In Low-Density Forest Biomass, Furqan Nezar, Shireen Jawad, Matthias Winter, Anwar Zeb

Baghdad Science Journal

Carbon dioxide is the main greenhouse gas contributing to global warming risk. Forest biomass is crucial for the sequestration of atmospheric carbon dioxide; however, the rate of decline in worldwide forest biomass is concerning and can be attributed to anthropogenic activities. Reforestation is essential in this situation to decrease the amount of C O₂ in the atmosphere. Efforts at reforestation can be evaluated according to the financial investment required for their execution. This work presents a nonlinear mathematical model that examines the impact of reforestation and the implementation of reforestation initiatives on regulating atmospheric CO₂ levels. The critical …

Fractal Dimension And Entropy Analysis Of Medical Images For Knn-Based Disease Classification, Krishna Mahapatra, Selvakumar R

Baghdad Science Journal

The study of medical image-based disease detection has witnessed a notable surge in interest and success with computational methods. This work proposes a novel framework to detect diseases at earlier stages from medical images, using mathematical model and Machine Learning. Introduce two new quantitative measures for COVID-19 and Tumor disease detection: image uncertainty based on Shannon entropy and image complexity based on fractal dimension. Our result demonstrated that in COVID-19 positive images exhibited skewed pixel distribution due to the hazy regions resulting in lower entropy values for diseased cases compared to healthy ones. The second quantity, fractal dimension was measured …

Facebook Comments-Based Assessment Model For Food Product Companies Using Four Machine Learning Methods With Arabic/Iraqi Lexicon, Raad Sadi Aziz, Sura Mazin Ali, Ahmed T. Sadiq

Baghdad Science Journal

People's need for food is increasing day after day due to the large population increase that has occurred in human society, which has led to a significant increase in the activity of food product manufacturing companies in the world. Hence the necessary need to evaluate the performance of food production companies. We found that the best way to evaluate the performance of these companies is through social media comments, because it is the newest and most common method among people. In this paper, 4 machine learning techniques were relied upon to evaluate participants' comments in evaluating food production companies after …

Ai-Assisted Model-Guided Image Reconstruction Methods For Photoacoustic And Ultrasound Computed Tomography, Luke Joseph Lozenski

McKelvey School of Engineering Graduate Student Theses & Dissertations

Photoacoustic computed tomography (PACT) and ultrasound computed tomography (USCT) are two emerging medical modalities that hold great promise for both pre-clinical and clinical imaging applications, including cancer diagnosis and management. PACT is a hybrid imaging modality that combines benefits from both optical and acoustic imaging to provide high contrast images of biological absorbers. USCT is an ultrasound imaging modality that provides high-resolution quantitative images of acoustic properties utilizing accurate physics models. Both PACT and USCT can be applied for monitoring or diagnosis of cancer and are non-invasive and radiation free. However, both imaging modalities are in the early stages of …

Quantifying Treatment Response To A Macrophage-Targeted Therapy In Combination With Immune Checkpoint Inhibitors After Exposure To Conventional Chemotherapy, Shelby N. Bess, Gaven K. Smart, Timothy J. Muldoon

Biomedical Engineering Faculty Publications and Presentations

Background: Conventional chemotherapeutic agents, such as 5-fluorouracil (5-FU), can exert anti-tumor effects through immunogenic cell death (ICD) induction. Researchers have found hallmarks that quantify ICD (such as the translocation of HMGB1 and calreticulin). Although chemotherapeutic agents can induce ICD, they increase the expression of immune checkpoints, limiting their effectiveness. Studies have emphasized the importance of investigating the heterogeneous responses of cells co-localized in a solid tumor (macrophages, tumor cells, etc.) to ICD induction. However, these studies were performed in vivo, which limits the collection of information on cell-cell interactions due to model complexity.

Methods: In this study, we used a …

Scarabs From A Middle Bronze Age Ii Tomb (Tomb 1) At Sasa, Daphna Ben-Tor

'Atiqot

No abstract provided.

Middle Bronze Age Ii Burials At Sasa, Upper Galilee (Tomb 1 And Graves 37, 39), Patricia Smith

'Atiqot

No abstract provided.

Middle Bronze Age Ii Tombs At Kibbutz Sasa, Upper Galilee (Tomb 1 And Graves 37, 39), Sarah Ben-Arieh

'Atiqot

No abstract provided.

Vessel-Covered Mamluk-Period Tombs On The Israeli Coastal Plain, In Light Of The Excavation On Danny Mass Street, Ramla, Yossi Elisha, Amir Gorzalczany, Hagit Torgë

'Atiqot

No abstract provided.

An Engraved Mercury Gemstone From The Roman–Byzantine-Period Necropolis South Of Tel Ashqelon, Noé D. Michael

'Atiqot

No abstract provided.

A Roman–Byzantine-Period Necropolis South Of Tel Ashqelon, Noé D. Michael, Sa‘Ar Ganor

'Atiqot

No abstract provided.

A Settlement And Two Mausolea From The Roman Period At Khirbat Umm Edh-Dhiyab, Ramat Bet Shemesh, Pablo Betzer, Igal Radashkovsky, Roy Albag

'Atiqot

No abstract provided.

Burial Caves From The Roman And Byzantine Periods And An Agricultural Settlement At Ḥorbat Mitla, Mount Carmel, Jacob Sharvit, Dror Planer, Ofra Barkai

'Atiqot

No abstract provided.

Making The Invisible Visible: Burial Customs In Late Roman–Byzantine-Period Western Galilee, Based On Organic Remains Adhering To Metal Objects, Ádám Bollók, Ayelet Dayan, Naama Sukenik

'Atiqot

No abstract provided.

Pig Sacrifice And Feasting In Roman Funerary Practices: A Case Study Of The Roman Legionary Cemetery At Legio, Lee Perry-Gal, Greg Leyfirer, Matthew J. Adams, Yotam Tepper

'Atiqot

No abstract provided.

Unique Lion-Headed Handles From A Roman-Period Cist Tomb South Of Khirbat Ibreika, Elie Haddad, Elisheva Zwiebel

'Atiqot

No abstract provided.

The Cave Of Salome: A Second Temple Period Royal Burial Estate In The Judean Shephelah, Nir-Shimshon Paran, Vladik Lifshits

'Atiqot

No abstract provided.

Death And Burial In The Polytheistic Communities Of The Hellenistic Southern Levant, Philip Ebeling, Achim Lichtenberger, Oren Tal

'Atiqot

No abstract provided.