Digital Commons Network^™

Neurophysiology And Endocrine Responses To Hunger And Satiety Mechanisms: The Brain-Gut Crosstalk, Nour Shakir Rezaieg, Muthanna M. Awad

Karbala International Journal of Modern Science

Background: Obesity is a main public health problem which substantially increases the risk of many diseases. The complex neural circuitry controls energy homeostasis and food consumption by the incorporation of hormonal and neural signals. Circulating hormones, in specific the gut hormones, have been found to be very important in appetite regulation. These hormones transfer energy situation signs to the brain throughout three principle paths: the circulation system, activation of the vagus nerve, and direct modification of main brain regions such as the hypothalamus and brainstem. The control of food eating is not exclusively dependent on the homeostatic processes, rather it …

A Novel Chaotic Dna-Based Image Cryptosystem Leveraging Euclidean Division, Dynamic Josephus Traversal, And Reservoir Computing, Ahmed Kareem Shibeeb, Salah Albermany, Sadiq A. Mehdi

Karbala International Journal of Modern Science

This study presents a new chaotic DNA-based image cryptosystem that combines Euclidean division, dynamic Josephus traversal (DJT), and reservoir computing to address the weaknesses of current methods. Old chaotic DNA cryptosystems usually have problems such as using the same keys for different messages, simple DNA processes, and being vulnerable to attacks where the attacker can choose the input or try many options. The cryptosystem in this study uses a 7D hyperchaotic system that starts with keys created from SHA-512 hashes to produce changing keystreams based on the plaintext, making it very strong against such attacks. The proposed cryptosystem uses a …

The Cortical Motor Map For The Extensor Digitorum Communis Muscle Fails To Increase In Treatment-Related Clinically Significant Upper Limb Post-Stroke Recovery, Tomoko Kitago, Joshua Silverstein, Michael B. Gerber, Charlene Thomas, Linda M. Gerber, Gary W. Thickbroom, Dylan J. Edwards

Moss-Magee Rehabilitation Papers

Objectives: Cortical reorganization has been proposed as a mechanism for motor recovery of the upper limb. The objective of this study was to determine if intervention-related clinical improvement in post-stroke hemiparesis is associated with enlarged motor cortex representation. Methods: Data were analyzed from a single site subset of the NICHE trial. Clinical assessments of upper limb movement (Fugl-Meyer Upper Extremity Motor Assessment, FM-UE, Action Research Arm Test, ARAT, and Wolf Motor Function Test, WMFT) and transcranial magnetic stimulation (TMS) motor mapping of the extensor digitorum communis (EDC) muscle were performed in 23 participants (3–12 months post-stroke, 10 female, 40–88 yrs) …

Edward Condon, Edward S. Condon Jr.

We Are NIH Oral History Project

No abstract provided.

Understanding Humorous Contradictions In Comics: A Multi-Agent Debate Approach, Suparna Das

Master’s Dissertations

Recent advancements in large language models (LLMs) have demonstrated impressive reasoning capabilities, yet their ability to understand and generate nuanced humor—particularly in contexts involving juxtaposition and contradictory narratives—remains a significant challenge. This thesis explores the application of advanced reasoning techniques, specifically multi-agent debate, to enhance LLMs’ performance in understanding and interpreting humor derived from juxtaposed comic panels. . Leveraging the YesBut benchmark—a dataset designed to evaluate AI models on tasks ranging from literal description generation to deep narrative reasoning, we explore how multi-agent debate can address key limitations in current models, such as visual misinterpretation, reasoning gaps, and hallucination. By …

Location Selection Of Migrating Beetles Under Neutrosophic Model With Sensitivity And Comparative Analysis, Rabih Sbera, Ahmed A El-Douh, Darin Shafek, Tareef S. Alkellezli

Neutrosophic Systems with Applications

Location Selection of Migrating Beetles has different criteria to select the best location. So, multi-criteria decision making (MCDM) is used to deal with different and numerous criteria in this study. This study proposes an MCDM methodology to rank the locations and select the best criterion. The average method is used to compute the criteria weights. The locations are ranked using the root assessment method (RAM). This study uses eight criteria and 20 locations. We use the single valued neutrosophic numbers (SVNNs) to overcome uncertainty and vague information. The RAM methodology is used under the SVNNs. The results show that Availability …

Risk Management Of The Open Data Services Industry In Digital Transformation Under Neutrosophic Sets, Fadhl Ehsan Hadi, Mohammed Musa Mohammed, Noorhan Waleed Abdullah, Baraa Hasan Hadi

Neutrosophic Systems with Applications

The open data services industry is very important for artificial intelligence and digital transformations. The open data services industry has different risks and challenges, so this study proposed a multi-criteria decision making (MCDM) approach for risk management in open data services industry. This study uses the average method to compute the criteria weights and the WASPAS method to rank the alternatives. The triangular neutrosophic set (TNS) is used in this study to overcome uncertainty and vague information. It has three membership functions such as truth, indeterminacy, and falsity. This study uses nine criteria and 18 risks to be evaluated. The …

Type-2 Neutrosophic Numbers For Artificial Intelligence Software Choice For Cybersecurity Testing, O.M. Akash, We’Am Adel Talafha, Mamdouh Gomaa

Neutrosophic Systems with Applications

The choice of artificial intelligence (AI) software for cybersecurity testing is a multi-criteria decision-making approach (MCDM) due to it including different criteria. Evaluation decision making problems include uncertainty and vague information. So, the neutrosophic set is used in this study to overcome this uncertainty and vague information. It has three functions such as truth, indeterminacy, and falsity functions. Type-2 neutrosophic numbers is a type of neutrosophic set that includes nine membership functions. This study uses the average method of computing the criteria weights. The CoCoSo method is used to rank alternatives. Six experts and decision makers created the decision makers …

Neutrosophic Numbers For Selection Best Strategy For Dual Supply Chains With Green And Non-Green Products, Nada A. Nabeeh, Waleed Abd Elkhalik, Gawaher Soliman Hussein

Neutrosophic Systems with Applications

Dual supply chains with green and non-green products are an important aspect of supply chain management, which enable companies to balance traditional operations with ethical and eco-friendly practices to reduce carbon emissions. This study proposed a novel approach that combines the Probabilistic Simplified Neutrosophic Set (PSNS) with the Ranking of Alternatives Method (RAM) for the selection of best strategy selection for dual supply chains with green and non-green products. The novel approach uses PSNS as a representation of uncertainty, by incorporating probabilistic degrees of truth, indeterminacy, and falsity, which occurred in real life situations. Furthermore, RAM illustrates efficient ranking and …

Book Review: Building A God, Carl Lee Tolbert

The Journal of Values-Based Leadership

No abstract provided.

Raised Colorblind, Still Colorblind, Ritch Eich

The Journal of Values-Based Leadership

No abstract provided.

Water From Stone: Extracting Leadership Wisdom From Moses' Mistake In Striking The Rock, Hershey H. Friedman, Joshua Krausz

The Journal of Values-Based Leadership

This paper explores the leadership lessons embedded in the story of Moses striking the rock rather than speaking to it. While seemingly a simple act of disobedience, it highlights the crucial need for leaders to adapt their approach based on the situation. Just as Moses faced a new generation with different needs, leaders today must understand the complex interplay of social and psychological factors within their teams. Proactive problem-solving, rather than reactive responses, is critical. Furthermore, fostering a collaborative environment where individuals work towards a shared purpose, independent of a single leader, is essential to avoid dependency and encourage healthy …

Emerging Paths Of Presencing Leadership: A Nature-Inspired Framework For Cultivating Presencing As A Way Of Being, Olen Gunnlaugson

The Journal of Values-Based Leadership

This article reimagines leadership as an ecologically attuned practice of presencing, grounded in ethical responsiveness to nature’s underlying generative intelligence. It invites leaders to cultivate a nature-informed sensibility and imaginal attunement to emergence. Rooted in three naturesourced, orienting principles — the Rhizomic, Telluric, and Heliotropic — this framework integrates Dynamic Presencing’s (DP) foundational gestures of letting go, letting be, and letting come. These principles guide leaders through three interwoven narrative phases of leadership apprenticeship: Coming Home, Being Home, and Venturing Forth from Within. The Rhizomic principle invites a grounded, non-linear mode of leadership rooted in humility and openness, supporting leaders …

Taking Kinship Into The Classroom By Indigenous Knowing: We Are All Related Somehow, Charlton Long

Journal of Indigenous Research

This article explores the integration of Indigenous knowledge into the classroom. It has been claimed that studies which do not promote revitalization of Indigenous communities should not be conducted. However, this article's intent is to support Indigenous communities and our way of knowing. The purpose of this paper is to stimulate thinking within Indigenous educational communities about the possibilities of incorporating kinship within students’ and teachers’ interactions for successful educational purposes. An alternative approach to how teachers and students interact in the classroom. This topic will also demonstrate the importance of Indigenous epistemologies with a theory that permits Indigenous scholars …

Censorship In The Media

Communication Research Trends

The principle of freedom of expression in the press, book publishing and broadcasting has been one of the hard-won battles in human history. Without this freedom, a democratic society,, could not exist. Yet every community and nation has to make painful decisions about what will, or will not be communicated. Libel and privacy are obvious examples. Otherwise our societies would virtually disintegrate. Does freedom of speech have limits? If so, how do we decide on these limits?

New forms of censorship are always creeping in. Currently it is insinuated that consumer protection groups such as Action for Children's Television in …

The Language Of Film And Television

Communication Research Trends

An increasing number of people receive most of their news, entertainment and even religious inspiration through the visual media of film, television or illustrated magazines. We all "watch" television.James Monaco notes that some cats watch television attentively! But how well do we grasp the specific language of the visual media?

In countries such as the U.S., there is evidence that the post-1950 generation that has grown up with television has a pattern of thinking more attuned to the visual than to print media. Yet, some cross-cultural studies suggest that many American children, for all of the long hours of TV …

New Tax Exemption Program For Doing Business In Puerto Rico, Angel L. Castro

Tax Adviser

No abstract provided.

Earthjustice: The Role Of The African Regional Human Rights System In Containing Climate Change, Bright Nkrumah, Ebenezer Durojaye, Maria Usang Assim

Journal of African Policy Studies

At the turn of the millennium, the landscape of Africa has been punctuated by intense weather conditions. With a disproportionate percentage of the continent’s population bearing the brunt of climate-induced heatwaves, deluges, and drought, it is expected that this phenomenon will spur regional climate litigation. The essay argues that although there is an evolution of climate cases submitted at the national level, this development has not evolved to the African regional human rights system. The lack of cases at the regional level beckons one to explore why (potential)victims are unable or unwilling to explore these mechanisms given their role in …

The Spectrum Of Childhood-Onset Lower Motor Neuron Disease Of Spinal Muscular Atrophy Phenotype Associated With Survival Motor Neuron-2 Gene Deletion, Somenath Ganguly, Durga Prasad Chakraborty, Satyabrata Roychoudhury, Madhumita Nandi, Suman Das

Journal of Pediatric Neurology

Pediatric lower motor neuron disease is clinically and genetically heterogeneous. We characterized disease progression among children with the spinal muscular atrophy (SMA) phenotype having 2:0 (group A) and 2:1 (group B) of the survival motor neuron 1/2 (SMN1:SMN2) genotype over 1 year. We included children aged 0 to 12 with the SMA phenotype between January 2018 and December 2021. Their demographic, clinical (Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders [CHOP-INTEND] scores), electrophysiological, radiological, and genetic data were collected from past medical records. The sequential CHOP-INTEND scores and the compound muscle action potential (CMAP) amplitudes were compared using an …

Aldh7a1 Gene And Its Related Pyridoxine-Dependent Epilepsy, Flavia M.C. La Mendola, Tiziana Timpanaro, Daniela Caruso, Maria Teresa Garozzo, Santiago Presti, Catia Romano, Elena R. Praticò, Antonio Zanghì, Raffaele Falsaperla

Journal of Pediatric Neurology

Despite being classically reported as caused by mutations in solute carriers genes (SLC2A1), it has been recently shown that also mutations in ALDH7A1 can cause pyridoxine-dependent epilepsy (PDE). ALDH7A1 is a gene encoding for the antiquitin, an enzyme that catalyzes the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-α-aminoadipic semialdehyde/L-Δ1-piperideine 6-carboxylate. It is a highly treatable disorder, but nevertheless it is still not certain when to consider this diagnosis and how to test for it. It is possible to identify a classical form and an atypical one of PDE associated with more than 70 mutations of ALDH7A1 gene. The typical form is …

The Effectiveness Of Botulinum Toxin Injections To The Extremities In The Pediatric Population With Severe Cerebral Palsy: A Systematic Review, Debra A. Sala, Eduardo Del Rosario

Journal of Pediatric Neurology

The purpose of this review was to examine the effectiveness of botulinum toxin injections to the upper and lower extremities reported in studies of pediatric participants with severe cerebral palsy on improving ease of care, pain and motor function. PubMed, CINAHL, and Web of Science were searched using combinations of cerebral palsy and various types and abbreviations of botulinum toxin. Additionally, reference lists and citations of reviewed studies were searched. The results of 25 studies were reviewed: three randomized controlled trials (RCT), and 22 non-randomized studies of interventions involving only a botulinum toxin-treated group. Seven studies focused solely on the …

Beyond The Lawn: Bylaws For Biodiversity - Evidence-Based Recommendations For Future Practice And Policy Development, Nina-Marie Lister, Sabrina Careri

Cities and the Environment (CATE)

Across Canada and globally, there is growing momentum to mitigate the impacts of climate change and habitat loss on biodiversity. These challenges transcend the jurisdiction of any single government or agency. In response, people across urban areas are increasingly taking action, particularly through landscaping strategies that foster and support biodiversity at home in their gardens. In North American cities, private lands make up a significant and often majority of the urban matrix. As such, private lands offer opportunities to address anthropogenic socio-environmental impacts in cities in ways that complement municipal initiatives on public lands. Specifically, rewilding initiatives on private lands, …

The Criminal Record As A Death Sentence: Unmasking The Ignored Realities Of Formerly Incarcerated University Graduates On Professional Licencing Challenges, Mbongiseni Mdakane, Bongani Innocent Nkambule, Sindile Amina Ngubane

Journal of Prison Education Research

Recently it is increasingly common practice for universities and professional registration councils to probe into applicants’ criminal records as a precondition for admission. Using social constructionism, this qualitative study explored the experiences of six formerly incarcerated individuals previously sentenced to life imprisonment, who hold professional university degrees in Law, Education, Psychology and Social Work and investigated whether having a criminal record had any bearing when applying for professional registration. The results indicate that due to the perceived stigma of, and discrimination against a criminal record, there exist varying degrees of criminal record disclosure ranging from partial, to full and non-disclosure. …

The Rise Of Foss In India: Empirical Evidence And Insights From Cross-Sectoral Case Studies, Arul George Scaria, Suryaprakash Mishra, Shubham Shinde, Rashi Singhal

Research Reports

The report analyses the adoption of FOSS in India, primarily through case studies across four sectors (healthcare, education, finance, and software and IT services) and different types of organisations (start-ups, non-profits, medium, large, and public sector organisations). The study highlights both the benefits and challenges experienced by organisations using FOSS. The study illustrates that while organisations benefit from increased innovations, cost/ time savings, flexibility, and enhanced security, they also face challenges such as lack of enough skilled personnel and limited community support. Organisations are also seen taking a cautious approach to licensing, favouring permissive licenses over restrictive ones. Based on …

Cilia In The Brain Display Region-Dependent Oscillations Of Length And Orientation, Roudabeh Vakil Monfared, Sherif Abdelkarim, Pieter Derdeyn, Kiki Chen, Hanting Wu, Kenneth Leong, Tiffany Chang, Justine Lee, Sara Versales, Surya M. Nauli, Kevin Beier, Pierre Baldi, Amal Alachkar

Pharmacy Faculty Articles and Research

In this study, we conducted high-throughput spatiotemporal analysis of primary cilia length and orientation across 22 mouse brain regions. We developed automated image analysis algorithms, which enabled us to examine over 10 million individual cilia, generating the largest spatiotemporal atlas of cilia. We found that cilia length and orientation display substantial variations across different brain regions and exhibit fluctuations over a 24-h period, with region-specific peaks during light-dark phases. Our analysis revealed unique orientation patterns of cilia, suggesting that cilia orientation within the brain is not random but follows specific patterns. Using BioCycle, we identified rhythmic fluctuations in cilia length …

The Rise Of Foss In India: Empirical Evidence And Insights From Cross-Sectoral Case Studies, Arul George Scaria, Suryaprakash Mishra, Shubham Shinde, Rashi Singhal

Research Reports

The report analyses the adoption of FOSS in India, primarily through case studies across four sectors (healthcare, education, finance, and software and IT services) and different types of organisations (start-ups, non-profits, medium, large, and public sector organisations). The study highlights both the benefits and challenges experienced by organisations using FOSS. The study illustrates that while organisations benefit from increased innovations, cost/ time savings, flexibility, and enhanced security, they also face challenges such as lack of enough skilled personnel and limited community support. Organisations are also seen taking a cautious approach to licensing, favouring permissive licenses over restrictive ones. Based on …

The Rise Of Foss In India: Empirical Evidence And Insights From Cross-Sectoral Case Studies, Arul George Scaria, Suryaprakash Mishra, Shubham Shinde, Rashi Singhal

Research Reports

The report analyses the adoption of FOSS in India, primarily through case studies across four sectors (healthcare, education, finance, and software and IT services) and different types of organisations (start-ups, non-profits, medium, large, and public sector organisations). The study highlights both the benefits and challenges experienced by organisations using FOSS. The study illustrates that while organisations benefit from increased innovations, cost/ time savings, flexibility, and enhanced security, they also face challenges such as lack of enough skilled personnel and limited community support. Organisations are also seen taking a cautious approach to licensing, favouring permissive licenses over restrictive ones. Based on …

Host Plant Resistance To Stink Bugs In Commercial Soybean Varieties, Cristofer Martinez

LSU Master's Theses

Soybean, Glycine max (L.) Merr. (Fabales: Fabaceae), is a major crop in Louisiana, where stink bugs (Hemiptera: Pentatomidae) are economically important pests that reduce seed quality and yield. Among them, the redbanded stink bug, Piezodorus guildinii (Westwood), is considered the most damaging species in the southern U.S. soybean system. Recently, Euschistus quadrator (Rolston), historically a minor pest, has increased in abundance and now dominates the brown stink bug complex in Louisiana soybean fields. While P. guildinii has been widely studied, little is known about E. quadrator.

Given the increasing pest complexity, sustainable management strategies are needed to target …

Investigation Of Subcellular Damage And Long-Term Non-Cancerous Cardiovascular Effects Following Whole-Body Photon Irradiation, Nousha Afshari

LSU Doctoral Dissertations

Current radiobiological models focus primarily on nuclear DNA damage and fail to fully explain radiation-induced noncancerous health effects. This dissertation investigates whether non-nuclear subcellular structures contribute to radiation-induced biological damage through experimental biomarker analysis and computational microdosimetry. The central hypothesis posits that whole-body photon irradiation results in subcellular non-nuclear damage, specifically increased circulating mitochondrial DNA concentrations, that correlates with radiation dose and long-term noncancerous effects such as cardiovascular disease.

Specific Aim 1 measured mitochondrial and nuclear DNA concentrations in banked blood samples from 72 Chinese rhesus macaques that previously received whole-body photon irradiation ($0-10$ Gy) from Cobalt-60 or LINAC sources. …

Establishment Of A Reverse Genetics System For Studying Human Immune Functions In Mice, Priya Pal, Shuai Gao, Hongbo Gao, Xiwen Qin, Marina Cella, Qiankun Wang, Liang Shan

2020-Current year OA Pubs

Reverse genetics approaches in mice are widely used to understand gene functions and their aberrations in diseases. However, limitations exist in translating findings from animal models to human physiology. Humanized mice provide a powerful bridge to understanding human physiology and mechanisms of disease pathogenesis while maintaining the feasibility of working with small animals. Methods for generating humanized mouse models that allow scientists to probe contributions of particular genes have been rudimentary. Here, we established an efficient method for generating genetically modified human cord blood-derived CD34