Digital Commons Network^™

High Glucose In Diabetic Hyperglycemia Perturbs Lymphocyte Serca-Regulated Ca2+ Stores With Accompanying Er Stress And Signaling Dysfunction, Md N. Uddin, James L. Graham, Peter J. Havel, Roshanak Rahimian, David W. Thomas

Pacific Faculty Work

It is well recognized that patients with type 2 diabetes mellitus (T2DM) exhibit significant impairment of immune function resulting in a higher frequency of infections. We hypothesize in this study that a likely contributor to immune dysfunction in T2DM is alteration of T lymphocyte signaling functions induced by chronic hyperglycemia. In this study we have utilized the established UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) rat model of human T2DM to investigate whether progressive hyperglycemia diminishes T cell receptor (TCR)-releasable endoplasmic reticulum (ER) Ca²⁺ stores, an essential early antigen-stimulated signal driving T cell activation. Furthermore, results from this study …

Preparation And Properties Of Rutin-Casein Complexes, Zhang Nan, Liu Lili, Yang Le, Li Sisi, Zhang Xinyuan

Food and Machinery

［Objective］ To investigate the effect of complexes produced by protein -polyphenol interaction on the bioavailability of polyphenols and proteins.［Methods］ Rutin -casein complexes are prepared using rutin and casein as raw materials.Their physicochemical and structural properties are analyzed.［Results］］ The optimal preparation conditions for the rutin -casein complexes are determined as follows:mass ratio of rutin to casein =1.89∶1.00,reaction time of 5.94 h,pH 8.5,and temperature of 50 ℃.Under such conditions,the binding degree is 40.23%.Compared with casein,the complexes exhibit a decrease in emulsifying activity index (8.47 m2/g) and emulsifying stability (9.39%).The solubility increases by 5.11%,surface hydrophobicity is significantly enhanced,and antioxidant activity markedly improves (P<0.05).Scanning electron microscopy reveals that the rutin -casein complexes display a lamellar structure with smooth surfaces,which may contribute to its functional properties.Infrared spectroscopy demonstrates peak broadening and redshifts in the amide I and II bands,and fluorescence intensity (including synchronous fluorescence ) decreases due to fluorescence quenching.It indicates that rutin alters the secondary structure and conformational arrangement of casein.［Conclusion］ Compared with the uncomplexed casein,the rutin -casein complexes are enhanced in solubility,surface hydrophobicity,and antioxidant activity.引用格式：张楠，刘丽莉，杨乐，等.芦丁—酪蛋白复合物的制备及特性研究 ［J］.食品与机械，2025，41（7）：9-17.C itation:ZHANG Nan,LIU Lili,YANG Le,et al.Preparation and properties of rutin-casein complexes [J].Food & Machinery,2025,41(7):9-17.

Effects Of Sodium Chloride Treatment On The Functional Characteristics And Structure Of Porcine Plasma Protein, Wang Deqiang, Zhao Longyuan, Tang Huaijian, Ma Yihao, Jia Feng

Food and Machinery

［Objective］ To explore the effects of sodium chloride (NaCl ) on the functional and structural properties of porcine plasma proteins (PPP),with the aim of providing a reference for the practical application of PPP.［Methods］ PPP was treated with different concentrations of NaCl (0~1.0 mol/L ),and changes in its functional and structural properties were measured using ultraviolet -visible spectrophotometry,laser particle size analysis,and Zeta potential analysis.［Results］］ NaCl promoted the solubility of PPP,reaching a peak at 0.2 mol/L.With further increases in NaCl concentration,solubility showed a downward trend.The trends in surface hydrophobicity and emulsifying properties of PPP changed at 0.8 mol/L,with maximum increases of 69.75% …

Occurrence Of Pesticides In Oregon Coastal Waters And Effects On The Intertidal Sea Anemone, Anthopleura Elegantissima, Gabriella Mae Bleil

Dissertations and Theses

Pesticides are used globally for a wide range of applications including agricultural, forestry, roadsides, freshwater systems, and personal use. While pesticides have ensured efficient crop production, they are frequently transported away from application sites and are ubiquitous in terrestrial and aquatic environments. Pesticides are often detected in watersheds and rivers globally, which can have unintentional toxic effects on non-target organisms by interfering with cellular processes, behavior, feeding, reproduction, and disrupting endocrine processes. The aggregating anemone, Anthopleura elegantissima, is an important species along the North American Pacific coast due to its symbiotic relationships that contribute to high productivity, and its …

Antibiotic Use In Rural Kenyan Livestock: Navigating Misuse, Experience Gaps And Amr Risks, Lucy Obolensky, Esbon Wambugu, Edna Kubai, Iain Doig, Miriam Beattie, Michael Dillon

Peninsula Medical School

Antimicrobial resistance (AMR) is an escalating global health threat, with the greatest risk observed in low- to middle-income countries, particularly in the global south. The World Health Organization advocates for a One Health approach to address AMR, promoting collaboration across sectors, including in agriculture. This study aims to enhance understanding of antimicrobial use and stewardship in livestock within pastoralist communities in northern Kenya, where there is limited information. The study employed a qualitative approach, using semi-structured interviews to gather data on farming practices and antibiotic use. Interviews were conducted by trained volunteers proficient in Swahili and Ma (a Maasai language), …

Mir-302a/B/D-3p Differentially Expressed During Frontonasal Development Is Sensitive To Retinoic Acid Exposure, Chihiro Iwaya, Akiko Suzuki, Goo Jun, Junichi Iwata

Faculty, Staff and Student Publications

Any failure in frontonasal development can lead to malformations at the middle facial region, such as frontonasal dysplasia, midfacial clefts, and hyper/hypotelorism. Various environmental factors influence morphogenesis through epigenetic regulations, including the action of noncoding microRNAs (miRNAs). However, it remains unclear how miRNAs are involved in the frontonasal development. In our analysis of publicly available miRNA-seq and RNA-seq datasets, we found that miR-28a-5p, miR-302a-3p, miR-302b-3p, and miR-302d-3p were differentially expressed in the frontonasal process during embryonic days 10.5 to 13.5 (E10.5–E13.5) in mice. Overexpression of these miRNAs led to a suppression of cell proliferation in cultured mouse embryonic frontonasal mesenchymal …

Hepatitis Patients Undergoing Cardiac Surgery: A Single-Center Retrospective Study, Jin-Long Ju, Yun-Tai Yao, Jun Li, Zhi Cheng, Ling-Ling Fan, Yu-Long Zhong

Faculty, Staff and Student Publications

This study aimed to investigate whether there is difference among various clinical variables, especially blood loss and total drainage volume, among patients with different types of hepatitis undergoing cardiac surgery. A retrospective study was performed on 150 hepatitis patients (127 hepatitis B and 23 hepatitis C) who underwent cardiac surgery at a single cardiovascular center in 2020. Data on their preoperative, intraoperative, and postoperative variables were collected and statistically analyzed to assess the inter-group differences in the following variables: intraoperative blood loss, postoperative drainage volume, proportion of patients treated with blood transfusion, proportion of patients treated with vasoactive drugs, and …

Investigation Of The Interaction Between Diethyl Phthalate And Ovalbumin Via Spectroscopic Techniques And Molecular Docking, Fu Chen, Huang Qun

Food and Machinery

［Objective］ To explore the interaction mechanism between diethyl phthalate (DEP ) and ovalbumin (OVA ) using multispectral analysis and molecular docking techniques.［Methods］ The Stern -Volmer equation is applied to study the fluorescence quenching mechanism of OVA by DEP,as well as to determine the binding constants and the number of binding sites between them.Thermodynamic parameters are used to identify the primary types of interaction forces.Based on Förster's non -radiative energy transfer theory,the energy transfer efficiency and binding distance between DEP and OVA are calculated.Molecular docking simulations are used to investigate the interaction forces between DEP and OVA.［Results］］ DEP can statically quench …

Lipid-Lowering Effect And Mechanism Of Walnut Oil, Xie Shanshan, Chen Wenli, Cui Shuchun

Food and Machinery

［Objective］ To study the effect of walnut oil on lipid metabolism and elucidate its mechanism of action.［Methods］ A high -fat diet is used to establish a high -fat model of SD rats,and 500,1 000,and 1 500 mg/kg undiluted walnut oil is used for gavage intervention experiments.After 8 weeks of intervention,the changes in body weight,organ indexes,serum lipid biochemical indicators,and serum antioxidant related indicators of SD rats are measured to observe the effects of walnut oil on organs,blood lipids,and antioxidant capacity.The expression of ABCA 1 mRNA,ABCG 1 mRNA,and SREBP 2-HMGCR signaling pathway and PPAR α-LXRα-CYP 7A1 signaling pathway genes in rat liver …

Progress In The Application Of Molecularly Imprinted Electrochemical Sensors In The Detection Of Veterinary Drug Residues, Han Yanrong, Chen Yanrong, Wang Chenyu, Kuang Yishan, Zhang Bo

Food and Machinery

Veterinary drugs play a crucial role in ensuring the healthy development of the livestock industry.However,improper or excessive use of veterinary drugs may pose threats to the environment and human health.To achieve effective monitoring of veterinary drug residues,various detection technologies have emerged.Among them,molecularly imprinted electrochemical sensors (MIECSs ) combines the high recognition specificity of molecularly imprinted polymers (MIPs ) with the rapid and sensitive advantages of electrochemical analysis,becoming a powerful tools in the detection of veterinary drug residues and demonstrating great application potential.However,its transition to large -scale application still faces many challenges.This article systematically reviews the progress in the application of …

Conformational Ligand-Directed Targeting Of Calcium-Dependent Receptors In Acute Trauma, Renata Pasqualini, Christopher Markosian, Daniela I Staquicini, Andrey S Dobroff, Esteban Dodero-Rojas, Paul C Whitford, E Magda Barbu, Julianna K Bronk, Marina Cardó-Vila, Dawn R Christianson, Emmanuel Dias-Neto, Wouter H P Driessen, Liliana Guzman-Rojas, Serena Marchiò, Diana N Nunes, Francislon S De Oliveira, Michael G Ozawa, Bettina Proneth, Roberto Rangel, Tracey L Smith, Glauco R Souza, Fernanda I Staquicini, Fenny H F Tang, Wallace B Baze, João C Setubal, John W Burns, Michael A Dubick, Juri G Gelovani, Andriy I Batchinsky, Jon E Mogford, Charles E Wade, John B Holcomb, Stephen K Burley, José N Onuchic, Wadih Arap

Faculty, Staff and Student Publications

Background: Trauma is a leading cause of mortality, but injury-specific molecular targets remain largely unknown. We hypothesized that distinctive yet unrecognized tissue targets accessible to circulating ligands might emerge during trauma, thereby underscoring a trauma-related proteome.

Methods: We screened a peptide library to discover targets in a porcine model of major trauma: compound femur fracture with hemorrhagic shock. Bioinformatics yielded conserved motifs, and candidate receptors were affinity purified. In silico and in vitro approaches served to investigate possible associations between candidate receptors and calcium, a major component of skeletal muscle and bone. In vivo homing and molecular imaging (PET/MRI and …

Vitamin K And Women's Health: A Review, Sharifa Alblooshi

All Works

Vitamin K is a fat-soluble vitamin essential in various physiological functions such as blood coagulation, bone metabolism, cardiovascular health, glucose regulation, immune function, neuroprotection, and vascular health. In this narrative review, studies from databases including PubMed, Google Scholar, Scopus, and the institutional database of Zayed University were selected. The role of vitamin K in women's health, with a focus on osteoporosis, postmenopausal health, cardiovascular health, diabetes, cancer, kidney health, brain health, vascular health, and pregnancy were explored. The role of vitamin K in activating vitamin K-dependent proteins is essential for many of its functions. Vitamin K-dependent proteins such as osteocalcin …

Impact Of Sanitation System Types On Residential And Environmental Presence Of Human Waste And Parasites In Alabama, Brandon Hunter, Catherine Coleman Flowers, Rojelio Mejia, Marc Arnold Deshusses

Faculty, Staff and Students Publications

Lowndes County is a predominantly Black rural county in Alabama, in the United States, which has a historical and current legacy of racial discrimination, creating inequitable infrastructure access and adverse health impacts. Over 80% rely on on-site sanitation infrastructure and most are failing. A community assessment of exposure to untreated sewage was conducted using samples from residential drinking water, surface swabs, and soil combined with environmental water and soil samples using culture-based and quantitative polymerase chain reaction (qPCR) methods. Testing varied slightly across samples, due to difficulty of access or availability. Of 43 households, 68% and 55% of houses had …

Oral Dosing Of The Nucleoside Analog Obeldesivir Is Efficacious Against Rsv Infection In African Green Monkeys, Jared Pitts, J Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicholas C Riola, Arya Vijjapurapu, Meghan S Vermillion, Stacey Eng, Christopher Richards, Dong Han, Jason K Perry, Subhra Chaudhuri, Szu-Wen Liu, Clarissa Martinez, Nadine Peinovich, Kai-Hui Sun, Arthur Cai, Ross Martin, Jasmine Moshiri, Charlotte Hedskog, Darius Babusis, Dustin S Siegel, Rao Kalla, Vasanthi Avadhanula, Pedro A Piedra, Kim Stobbelaar, Peter L Delputte, Caleb Marceau, Roberto Mateo, Evguenia Maiorova, Hongmei Mo, Raju Subramanian, Richard L Mackman, Tomas Cihlar, Simon P Fletcher, John P Bilello

Faculty, Staff and Students Publications

Respiratory syncytial virus (RSV) is a significant cause of morbidity and mortality in high-risk populations. Although prophylactic options are available, there are no effective oral therapeutics for RSV infection. Obeldesivir (ODV) is an orally bioavailable prodrug of the nucleoside analog GS-441524, which is converted intracellularly to its active nucleoside triphosphate and inhibits the RSV RNA polymerase. Here we report the potent antiviral activity of ODV against geographically and temporally diverse RSV A and B clinical isolates (EC50: 0.20–0.66 μM). Resistance selection studies with ODV and GS-441524 against RSV identify a single amino acid substitution, I777L, in the L polymerase with …

Src/Fn1 Pathway Activation Drives Tumor Cell Cluster Formation And Metastasis In Lung Cancer: A Promising Therapeutic Target, Zujun Que, Zhichao Xi, Dan Qi, Rongchen Dai, Yang Li, Mengfan Liu, Bin Luo, Jiajun Liu, Pan Yu, Yun Yang, Erxi Wu, Hongxi Xu, Jianhui Tian

Children’s Nutrition Research Center Staff Publications

Lung cancer remains the leading cause of cancer-related death globally, with metastasis driven by circulating tumor cells (CTCs)-particularly clusters-being a major treatment challenge. Despite their critical role, the biological differences between single CTCs and CTC clusters remain unclear. Here, we comprehensively compared their behavioral, transcriptomic, and proteomic profiles in lung cancer models. Compared with single cells, CTC clusters present enhanced metastatic potential, greater survival in the bloodstream and increased resistance to microenvironment. Mechanistically, the Src/FN1 pathway is centrally activated in clusters, promoting intercellular cohesion and protecting against immune clearance and stress in circulation. Pharmacological inhibition of Src with the clinical …

Combination Hyaluronic Acid And Multipotent Stromal Cells Fails To Improve Rat Knee Oa Outcomes Compared To Cells Alone, Kennedy Michele Davis, Megan Hamilton, Donald Muathe, Aldyn Wildey, Stephen Harrington, Douglas Bittel, Michael Filla, Lisa Stehno-Bittel

Faculty and Staff Publications

Introduction: Multipotent Stromal Cells (MSCs) are utilized as therapeutic agents for addressing musculoskeletal conditions, including knee osteoarthritis (OA). However, major challenges in the clinical application include maintenance of the cells in the joint capsule. Hyaluronic acid (HA) is endogenous in synovial joints and commercially available as a joint lubricant. We tested the hypothesis that delivery of MSCs in HA into an OA rat knee model could improve outcomes.

Methods: Rat bone marrow MSCs were suspended in a commercially available HA paste, and cell viability measured with live/dead stains. Biomarkers for MSC chondrogenesis and osteogenesis were monitored with PCR. MSCs with …

"Female Faithfulness Encouraged": Gendered Piety In Early American Print, Kadienne Sizemore

Ursidae: The Undergraduate Research Journal at the University of Northern Colorado

Following the American Revolution, membership in Baptist churches grew exponentially and the influence of the Baptist persuasion was significant. As one of the fastest growing Protestant denominations in early America, Baptists and their interests were often indicative of larger trends in religiosity. Conceptions of piety, including beliefs surrounding submission, faithfulness, and duty, were central to the structure of Baptist congregations and their proximate communities. This paper explores the role of gender in the discussion, presentation, and justification of Baptist notions of piety in their publications during the Early American Republic. To build on the work of historians exploring female autonomy …

Niche Conservatism And Sympatric Parallel Evolution May Help To Maintain Eight Nascent Tree Taxa Along A Sharp Elevation Gradient, Elizabeth A. Stacy, Rebecca Ostertag

Life Sciences Faculty Research

1. Patterns of niche partitioning among closely related taxa, such as those in incipient adaptive radiations, can provide clues into how niches are created, partitioned, and integrated over ecological and evolutionary time scales. Hawaiian Metrosideros is a ~3-MYO adaptive radiation of trees that dominates the Hawaiian Islands in continuous stands within islands and allows examination of niche partitioning at the early stages of adaptive radiation.
2. We monitored growth and survivorship over 2 years of seedlings derived from open-pollinated fruits of eight Metrosideros taxa distributed along the elevation gradient of Koʻolau Volcano, Oʻahu, under four combinations of light and phosphorus. We included …

The Carpet Bag Correspondence, Russell J. Desimone, Erik J. Chaput

Dorr Scholarship

In late December 1842 and early 1843 there appeared several newspaper articles in the Providence Journal under the caption of “The Carpet Bag” Correspondence. In all four letters were published in the local newspapers all claiming to be from the carpet bag. Two of the letters were written by Dutee J. Pearce of Newport to Thomas Dorr the leader of the suffrage movement in Rhode Island. The other two letters were written to Dorr by Dr. J.A. Brown and Louis Lapham. The second Pearce letter is interesting because it discusses giving the Black community a jury trial.

The Role Of Ecosystem Services In Holistic Conservation Within Protected Areas: A Case Study Of The Song Thanh National Park, Vietnam, Tuyen Nghiem, Sumeet Saksena, Hue T. Ha, Truong Dao, Toan Le, Huong D. Vu, Dien Nguyen, Truong Q. Hoc

Forest and Society

Vietnam has made a strong commitment to biodiversity conservation, as evidenced by its extensive network of protected areas. However, environmental issues persist in protected areas. Often, the resulting violence complicates the situation, making it more challenging to analyze and manage. We studied the perceptions of people in the buffer zone of the Song Thanh National Park, Quang Nam province, regarding the current status of ecosystem services (ES), the importance of ecosystem services, their changes over time, and people's participation in protecting ecosystem services. We employed a mixed-methods approach, combining qualitative and quantitative data. We conducted semi-structured interviews, focus group discussions, …

Community Perspectives On Engaging Stakeholders For Human-Sumatran Tiger Coexistence In The Bukit Barisan Selatan Landscape, Rinekso Soekmadi, Novriyanti Novriyanti, Burhanuddin Masy’Ud, Damayanti Buchori, Christine Wulandari, Ismanto Ismanto

Forest and Society

The Bukit Barisan Selatan (BBS) landscape, a vital habitat for the Sumatran tiger (Panthera tigris sumatrae), is increasingly degraded and fragmented by plantation and agricultural expansion, driving tigers into human-dominated areas and creating conflict zones beyond conservation boundaries. However, despite global frameworks like the Kunming-Montreal 2050 Biodiversity Framework and IUCN advocating coexistence by integrating ecological and socio-economic priorities, the practical implementation at the site level remains uncertain, particularly regarding local perspectives on coexistence and their alignment with competing stakeholder interests. This study analyzes the alignment of parties in the context of the potential coexistence of human-tiger conflicts in …

Cracked Doors, Open Questions: Does State V. Thompson Threaten Montana’S Privacy Tradition?, Dennis Stock

Montana Law Review

No abstract provided.

Social Forestry As Solution To Agrarian Conflicts? A Case Study Between Oil Palm Smallholders And Industrial Plantations In Jambi, Indonesia, Muhammad Reza Halomoan, Arya Hadi Dharmawan, Satyawan Sunito

Forest and Society

Extraction activities across Indonesia have caused drastic changes to forest ecologies. The Indonesian government responded to this through a policy of Industrial Plantation Forest concessions, which were given to the private sector in the hopes of overcoming damages from forest extraction activities while at the same time utilizing unproductive forest land. However, this policy does not pay attention to the existence of people who de facto control and use the land and has triggered new conflicts around agrarian claims based on different interpretations of land rights. In an effort to resolve conflicts, the government has implemented a community-based forest area …

The Patchwork Quilt Of Global Mangrove Conservation: Mapping The Landscape Of International Treaties, Pradip Kumar Sarker, Md Faisal Abedin Khan, Fredy Polo Villanueva, Lukas Giessen

Forest and Society

Mangroves at the land-sea interface offer invaluable goods and services through their unique ecosystem. Society has responded by developing governance mechanisms to manage these resources sustainably, which is crucial for societal well-being. The global environmental governance landscape is a complex network of treaty-based regimes addressing various ecological challenges. This study aims to examine the treaty-based regimes governing mangrove conservation, systematically mapping and identifying authoritative global mangrove regimes. It analyses the fragmentation scale regarding synergies, conflicts, and neutral relationships between global environmental treaties. Online scoping reviews and content analysis revealed that the Ramsar Convention serves as the legal authority of the …

Signifying The End Of Swidden? An Analysis Of Vocabulary Of The Fallow Stage Among A Kalimantan Indigenous Group, Indonesia, Syamsul Rijal, Muhammad Hasyim, Lukman Lukman, Ery Iswary

Forest and Society

This study examines how the Dayak Tunjung community in East Kalimantan, Indonesia, employs linguistic classifications to structure and transmit ecological knowledge within a traditional swidden agricultural system. It focuses on the vocabulary used to denote fallow stages and analyzes how generational shifts in language use reflect broader socio-ecological transformations. Data were collected through 16 semi-structured interviews and participant observation in Linggang Melapeh Village, stratified by age and occupation to capture intergenerational dynamics. The findings reveal that older generations retain a detailed lexicon tied to ecological succession and customary land practices, while younger members increasingly adopt shortened fallow cycles and show …

Impacts Of Urbanization On The Use Of Soil Amendments By Rice Farmers Along A Rural-Urban Continuum In Northeast Thailand, Sujitra Yodda, Suwit Laohasiriwong, Phrueksa Lawongsa, Tanabhat-Sakorn Sukitprapanon, A. Terry Rambo

Forest and Society

This study investigated the impact of urbanization on use of soil amendment by rice farmers in three villages along a rural–urban continuum in Northeast Thailand. It shows how urbanization influences their use of types and quantities of soil amendments. Data were collected by interviewing 150 farmers, focusing on types, quantities, sources, costs, and perceived effects of nine different amendments, including rice straw, chemical fertilizers, manures, and green manure. Results revealed significant declines in organic amendment use as villages become more urbanized, with rural farmers employing more diverse and greater quantities of organic amendments while periurban and urban farmers predominantly rely …

One Health Policy Communities’ Perspectives On Zoonoses Risk Factors And Management: A Multiple Qualitative Methods Approach, Lisset M. Dumet, Erin Kenzie, Julia M. Goodman, Veronika Merino Osorio, Vanessa Cruz Chavez, Ruth Atto, Percy Vilchez Barreto, Seth O’Neal

OHSU-PSU School of Public Health Faculty Publications and Presentations

Zoonoses emergence and endemicity are serious global public health problems that disproportionately affect low-resource settings. One Health (OH) serves as a framework to understand the interconnection of zoonoses risk factors and incentivizes collaboration, coordination, and communication among sectors. However, OH encounters barriers related to power imbalances, gaps in coordination, and conflicts of interest among diverse communities of practice, which are groups that share a problem and domain of interest and engage in collective learning. This research aims to elucidate the mental models of policy communities, which are representations of the environment, and how humans explain and predict their surroundings to …

Low-Magnitude High-Frequency Mechanical Vibration Enhances Osteogenesis In Human Pdl Cells Through Piezo1 Ion Channel, Mina Oh

Master's Theses (2009 -)

ABSTRACT LOW-MAGNITUDE HIGH-FREQUENCY MECHANICAL VIBRATION ENHANCES OSTEOGENESIS IN HUMAN PDL CELLS THROUGH PIEZO1 ION CHANNEL Mina Oh, D.M.D Marquette University, 2025 Introduction: Low-magnitude high-frequency (LMHF) mechanical vibration has been shown to enhance osteogenesis in various osteogenic tissues and cells, including periodontal ligament (PDL) cells, however its effectiveness remains relatively low. The Piezo1 mechanosensitive ion channel plays a critical role in mechanotransduction, however its specific involvement in the LMHF-induced osteogenesis is unknown. This study aims to elucidate the role of Piezo1 in mediating osteogenic responses in human PDL cells subjected to LMHF mechanical vibration. Materials and Methods: Human PDL cells were …

An Upper-Mesopelagic-Zone Carbon Budget For The Subarctic North Pacific, Brandon M. Stephens, Montserrat Roca-Martí, Amy E. Maas, Vinícius J. Amaral, Samantha Clevenger, Shawnee Traylor, Claudia R. Benitez-Nelson, Philip W. Boyd, Ken O. Buesseler, Craig A. Carlson, Nicolas Cassar, Margaret Estapa, Andrea J. Fassbender, Yibin Huang, Phoebe J. Lam, Oliver Marchal, Susanne Menden-Deuer, Nicola L. Paul, Alyson E. Santoro, David A. Siegel, David P. Nicolson

Faculty Publications

Mesopelagic zone (MZ) carbon budgets comparing supply with demand can be difficult to constrain due to the temporal and spatial offsets between key sources and sinks, their associated uncertainties, and potential sampling biases. To address these challenges, the EXport Processes in the Ocean from RemoTe Sensing (EXPORTS) campaign increased the number and variety of simultaneous measurements to monitor temporal variability in the MZ carbon budget using both a Lagrangian frame of reference and long-term autonomous observations. In this study, we collate a comprehensive combination of new and previously published organic carbon supply and demand measurements collected from the surface (5 …

Groo V. Montana Eleventh Judicial District Court: Montana’S Long-Arm Overreaches Into Cyberspace, Matthew Belle

Montana Law Review

No abstract provided.