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Rare Variants In Bmal1 Are Associated With A Neurodevelopmental Syndrome, Vishnu Anand Cuddapah, Dechun Chen, Bumsik Cho, Rebecca Moore, Mohnish Suri, Hana Safraou, Frederic Tran-Mau-Them, Ashley Wilson, Jacqueline Odgis, Atteeq U. Rehman, Carol J. Saunders, Shiva Ganesan, Vaidehi Jobanputra, Stephen W. Scherer, Ingo Helbig, Amita Sehgal Aug 2025

Rare Variants In Bmal1 Are Associated With A Neurodevelopmental Syndrome, Vishnu Anand Cuddapah, Dechun Chen, Bumsik Cho, Rebecca Moore, Mohnish Suri, Hana Safraou, Frederic Tran-Mau-Them, Ashley Wilson, Jacqueline Odgis, Atteeq U. Rehman, Carol J. Saunders, Shiva Ganesan, Vaidehi Jobanputra, Stephen W. Scherer, Ingo Helbig, Amita Sehgal

Manuscripts, Articles, Book Chapters and Other Papers

Through international gene-matching efforts, we identified 10 individuals with ultrarare heterozygous variants, including 5 de novo variants, in BMAL1, a core component of the molecular clock. Instead of an isolated circadian phenotype seen with disease-causing variants in other molecular clock genes, all individuals carrying BMAL1 variants surprisingly share a clinical syndrome manifest as developmental delay and autism spectrum disorder, with variably penetrant sleep disturbances, seizures, and marfanoid habitus. Variants were functionally tested in cultured cells using a Per2-promoter driven luciferase reporter and revealed both loss-of-function and gain-of-function changes in circadian rhythms. The tested BMAL1 variants disrupted PER2 mRNA …


Bacillus Isolate Compositions And Methods Of Using And Producing The Same, Billy M. Hargis, Lucas E. Graham, Kyle D. Teague, Juan D. Latorre, Samuel J. Rochell Aug 2025

Bacillus Isolate Compositions And Methods Of Using And Producing The Same, Billy M. Hargis, Lucas E. Graham, Kyle D. Teague, Juan D. Latorre, Samuel J. Rochell

Patents Granted

The present invention provides Bacillus isolates, as well as probiotic and animal feed compositions comprising said isolates, which may be included in the diet of poultry to improve growth performance with reduced energy diets. Methods of using these compositions to improve nutritional uptake or to reduce the incidence of footpad dermatitis in poultry are also provided.


Pre-Service Teachers’ Development Of Four C Skills In Early Field Experiences Through Reflective Writing, Weihsuan Lo, Deborah Romero Aug 2025

Pre-Service Teachers’ Development Of Four C Skills In Early Field Experiences Through Reflective Writing, Weihsuan Lo, Deborah Romero

Journal of Educational Research and Innovation

This longitudinal trend research study (Creswell & Guetterman, 2019) investigates how pre-service teachers (PSTs) in a K-12 licensure program that includes a Culturally and Linguistically Diverse (CLD) added endorsement develop the 4Cs (creative thinking, critical thinking, communication, and collaboration) through reflective writing during early field experiences. The study involved five PSTs who submitted three reflective journals during the 2020-2021 school year and nine PSTs who participated in an online virtual focus group. Compared to the 2019-2020 school year, where PSTs observed in-person classes, the shift to online learning in 2020-2021 resulted in maintained Analytic skills (M = 39.40) and increased …


The Shorthorn: February 16, 1968 Aug 2025

The Shorthorn: February 16, 1968

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: November 17, 1967 Aug 2025

The Shorthorn: November 17, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: October 6, 1967 Aug 2025

The Shorthorn: October 6, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: September 29, 1967 Aug 2025

The Shorthorn: September 29, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: July 7, 1967 Aug 2025

The Shorthorn: July 7, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: April 28, 1967 Aug 2025

The Shorthorn: April 28, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: April 14, 1967 Aug 2025

The Shorthorn: April 14, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: March 17, 1967 Aug 2025

The Shorthorn: March 17, 1967

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: April 15, 1966 Aug 2025

The Shorthorn: April 15, 1966

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: March 18, 1966 Aug 2025

The Shorthorn: March 18, 1966

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: February 11, 1966 Aug 2025

The Shorthorn: February 11, 1966

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: November 12, 1965 Aug 2025

The Shorthorn: November 12, 1965

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Shorthorn: May 7, 1964 Aug 2025

The Shorthorn: May 7, 1964

The Shorthorn Newspaper Collection: 1960s

No abstract provided.


The Prince & The Discourse, Niccolò Machiavelli Aug 2025

The Prince & The Discourse, Niccolò Machiavelli

Hannah Arendt Marginalia - All

New York, Modern library 1940

Call #: JC143 .M38 1940

Contains marginalia, underlining, marginal lining and endpaper notes.

PDF Information: 194 pages – 91mb


Antimémoires, André Malraux Aug 2025

Antimémoires, André Malraux

Hannah Arendt Marginalia - All

Paris, Gallimard, 1967

Call #:PQ2625.A716 A7 1967

Contains marginalia, underlining

PDF Information: 54 pages – 18.2 MB


Man’S Fate (La Condition Humaine), André Malraux Aug 2025

Man’S Fate (La Condition Humaine), André Malraux

Hannah Arendt Marginalia - All

Franklin Center, Pa. : Franklin Library, 1980

Call #: PQ2625.A716 C53 1934

Contains marginalia, underlining, and endpaper notes

PDF Information: 109 pages – 37.2 MB


Meaning In History, Karl Löwith Aug 2025

Meaning In History, Karl Löwith

Hannah Arendt Marginalia - All

Chicago: University of Chicago Press, 1949

Call #: D16.9 .L64 1949

Contains marginalia, underlining, marginal lining and endpaper notes (back of book).

PDF Information: 32 pages – 12.4mb


Lucretius On The Nature Of The Universe, Titus Lucretius Carus Aug 2025

Lucretius On The Nature Of The Universe, Titus Lucretius Carus

Hannah Arendt Marginalia - All

Harmondsworth, Middlesex ; Baltimore : Penguin Books, 1951

Call #: PA6483.E5 L4 1951

Contains underlining, marginal lining and endpaper notes

PDF Information: 31 pages – 18 MB


Notebook 1967-68, Robert Lowell Aug 2025

Notebook 1967-68, Robert Lowell

Hannah Arendt Marginalia - All

New York, Farrar, Straus and Giroux, 1969

Call #: PS3523.O89 A6 1969

Contains light underlining, endpaper notes and is inscribed by author.

PDF Information: 6 pages – 7.5 mb


From Hegel To Nietzsche: The Revolution In Nineteenth-Century Thought, Karl Löwith Aug 2025

From Hegel To Nietzsche: The Revolution In Nineteenth-Century Thought, Karl Löwith

Hannah Arendt Marginalia - All

New York, Holt, Rinehart and Winston, 1964

Call #: B803 .L623

Contains marginalia, underlining and marginal lining.

PDF Information: 82 pages – 61mb


Heidegger: Denker In Dürftiger Zeit, Karl Löwith Aug 2025

Heidegger: Denker In Dürftiger Zeit, Karl Löwith

Hannah Arendt Marginalia - All

Frankfurt am Main: Fischer, 1953

Call #: B3279.H49 L6 1953

Contains marginalia.

PDF Information: 12 pages – 9mb


Merleau-Ponty’S Critique Of Reason, Thomas Langan Aug 2025

Merleau-Ponty’S Critique Of Reason, Thomas Langan

Hannah Arendt Marginalia - All

New Haven, Yale University Press, 1966

Call #: B2430.M38 L3

Contains marginalia, underlining, marginal lining and endpaper notes.

PDF Information: 59 pages – 22mb


Two Treatises Of Civil Government, John Locke Aug 2025

Two Treatises Of Civil Government, John Locke

Hannah Arendt Marginalia - All

New York : Dutton, 1949

Call #: JC153 .L8 1949

Contains marginalia, underlining, marginal lining & endpaper notes

PDF Information: 61 pages – 4 MB


The Alienation Of Reason: A History Of Positivist Thought, Leszek Kolakowski Aug 2025

The Alienation Of Reason: A History Of Positivist Thought, Leszek Kolakowski

Hannah Arendt Marginalia - All

Garden City, N.Y., Doubleday, 1968

Call #: B831 .K613

Contains underlining and marginal lining

PDF Information: 28 pages – 2 MB


From The Closed World To The Infinite Universe, Alexander Koyré Aug 2025

From The Closed World To The Infinite Universe, Alexander Koyré

Hannah Arendt Marginalia - All

Baltimore, Johns Hopkins Press [1957]

Call #: BD511 .K67 1958

Contains marginalia and marginal lining

PDF Information: 84 pages – 26 MB


Renaissance Concepts Of Man, And Other Essays, Paul Oskar Kristeller Aug 2025

Renaissance Concepts Of Man, And Other Essays, Paul Oskar Kristeller

Hannah Arendt Marginalia - All

New York, Harper & Row, 1972

Call #: B780 .M3 K75 1972

Contains marginalia, underlining and marginal lining

PDF Information: 52 pages – 50 MB


The Presocratic Philosophers: A Critical History With A Selection Of Texts, G. S. Kirk, J. E. Raven Aug 2025

The Presocratic Philosophers: A Critical History With A Selection Of Texts, G. S. Kirk, J. E. Raven

Hannah Arendt Marginalia - All

Cambridge, University Press, 1962

Call #: B188 .K5 1962

Contains marginalia, underlining and marginal lining.

PDF Information: 127 pages – 53mb