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Unity And Kindness Day: A Transformative Event To Promote Equity, Diversity, And Inclusion, Adisa Cartwright, Michelle Santizo, Dahlia Maldonado, Kelli Obazee Aug 2025

Unity And Kindness Day: A Transformative Event To Promote Equity, Diversity, And Inclusion, Adisa Cartwright, Michelle Santizo, Dahlia Maldonado, Kelli Obazee

Creating Healthy Work Environments (CHWE)

Introduction: Following social unrest in 2020, nurses at a large health system advocated for structures that celebrate diversity, promote equity, and enhance inclusion. This led to the creation of the Unity in Diversity Nursing Professional Governance Council (UID). After a systemwide assessment of nurse wellbeing, a need to improve the practice environment was identified. This led UID to create the Unity in Kindness Day (UKD) event. Since 2022, UID has hosted UKD; a multi-campus and online event aimed at fostering a healthier work environment through promoting equity, diversity, and inclusion (EDI). UKD, hosted by nurses, invites all staff members to …

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Host, Microbiome, And Parasite: How Apicomplexan Microorganisms Interact With Gut Microbiota, Senia Bu, Andrew T. Ozga Aug 2025

Host, Microbiome, And Parasite: How Apicomplexan Microorganisms Interact With Gut Microbiota, Senia Bu, Andrew T. Ozga

Mako: NSU Undergraduate Student Journal

The gut microbiome, a complex ecosystem of microorganisms residing in the human gastrointestinal tract, plays a crucial role in maintaining overall health. It functions in immune system regulation, digestion, and protection against pathogens. Apicomplexan parasites, such as Toxoplasma gondii, Plasmodium spp., and Cryptosporidium spp., are major pathogens that can significantly disrupt the gut microbiota, leading to alterations in microbial composition and function. This review explores the bidirectional interactions between Apicomplexan parasites and the gut microbiome, focusing on how these parasites influence microbial diversity, immune responses, and host metabolism. It examines the mechanisms by which infection-induced inflammation, altered …

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The Residual Impact Of Slavery On How Enslaved Black Females Defined And Made Meaning Of Sexual Violence: A Content Analysis, Suzanne R. Bates Aug 2025

The Residual Impact Of Slavery On How Enslaved Black Females Defined And Made Meaning Of Sexual Violence: A Content Analysis, Suzanne R. Bates

Dissertations

Thompson-Miller & Picca (2016) and Feimster (2023) argued that enslaved African American women, and even free African Americans after the Civil War were victims of non-consensual sexual activity and rape. The NISVS report revealed that before the age of 18 years old, 35.5% of African American women experienced contact sexual violence, 29.5% experienced non-contact unwanted sexual encounters, and 20.7% experienced rape (Basile et al., 2022). Researchers of slave scholarship have made the case for the importance of including discourse on slavery and enslaved Black females’ experiences when discussing present day sexual violence among Black women in the US today (Balfour, …

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The American Politics Of Firearms - The Case Between Illinois And Missouri, Michael J. Thompson Aug 2025

The American Politics Of Firearms - The Case Between Illinois And Missouri, Michael J. Thompson

Dissertations

The issue of gun control is a hot topic in the field of American politics. It is a huge issue in the field of political science and in American public policy. In 2023, there were 18,874 firearm deaths in the United States, excluding suicides. The highest was in 2021 with the firearm related deaths at 21,068. One side argues that firearms can cause serious harm and death while the other side argues they can also reduce the rates of gun violence. There are different opinions on how to resolve the issue of mass shootings across the country. According to prior …

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Vanuatu And The International Court Of Justice: A Food Studies Approach To Climate Governance And Power, Amy Katherine Bentley Aug 2025

Vanuatu And The International Court Of Justice: A Food Studies Approach To Climate Governance And Power, Amy Katherine Bentley

Theses - ALL

Vanuatu is a leader among small island developing states (SIDS) working to influence global climate change governance, using international diplomacy as its best defense against the climate crisis. In 2023, Vanuatu spearheaded a successful campaign for the United Nations General Assembly to request an advisory opinion (AO) from the International Court of Justice (ICJ) clarifying nations’ legal obligations related to climate change. This study uses a food studies approach to explore Vanuatu’s success in its climate governance campaign, focusing on the relationships between food sovereignty, climate justice, and power. To investigate this subject, I used an interdisciplinary literature review and …

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A Morpho-Kinematic Model Of Molecular Line Emission In Planetary Nebulae, Diana E. Ryder Aug 2025

A Morpho-Kinematic Model Of Molecular Line Emission In Planetary Nebulae, Diana E. Ryder

Theses

Planetary nebulae (PNe), the late-stage remnants of low- to intermediate-mass stars, offer valuable insights into the final phases of stellar evolution and the enrichment of the interstellar medium via intermediate-mass star ejecta. Molecular emission from these objects serves as a powerful diagnostic for probing physical conditions, chemical composition, and kinematics of these ejecta. In this thesis, we describe the flexible, modular modeling framework we are developing to analyze high spatial and spectral resolution molecular emission-line data for planetary nebulae, as obtained by modern mm-wave interferometers such as the Submillimeter Array (SMA) and the Atacama Large Millimeter/submillimeter Array (ALMA). The Python- …

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Monitoring The Developmental Stages Of Calendula Officinalis L. Nutrients Efficacy Under Hot Weather Mitigation Through Nutrients In Haripur, Pakistan, Waseem Ahmed, Rafia Azmat, Shah Masaud Khan, Abdul Qayyum, Waseem Hassan, Adnan Noor Shah, Muhammad Hadi Abbas, Fatima M. Abbas, Tahani A.Y. Asseri, Ahmet Hakan Ürüşan Aug 2025

Monitoring The Developmental Stages Of Calendula Officinalis L. Nutrients Efficacy Under Hot Weather Mitigation Through Nutrients In Haripur, Pakistan, Waseem Ahmed, Rafia Azmat, Shah Masaud Khan, Abdul Qayyum, Waseem Hassan, Adnan Noor Shah, Muhammad Hadi Abbas, Fatima M. Abbas, Tahani A.Y. Asseri, Ahmet Hakan Ürüşan

Turkish Journal of Agriculture and Forestry

This study examines the effect of different doses of N and P fertilizer on Calendula officinalis L. (marigold) during the hot weather in summer (May–July) in Pakistan. The aim was to determine whether fertilization can help minimize the impacts of climate change. During the summer peak seasons (May, June, and July), the trial was conducted in potted plants with different N and P application levels to monitor the quality and quantity of C. officinalis. The results showed that the interactive effects (N × P) gave higher values for plant height, number of leaves, fresh weight, leaf length, and number of …

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Exploring The Genetic Diversity And Population Structure Of Serbian And Selected European Bread Wheat Cultivars Through Ipbs-Retrotransposon Markers, Rada Šućur, Amjad Ali, Parnaz Mortazavi, Muhammad Tanveer Altaf, Muhammed Tatar, Muhammad Azhar Nadeem, Bojan Jocković, Velimir Mladenov, Sotirios Fragkostefanakis, Yong Suk Chung, Faheem Shehzad Baloch Aug 2025

Exploring The Genetic Diversity And Population Structure Of Serbian And Selected European Bread Wheat Cultivars Through Ipbs-Retrotransposon Markers, Rada Šućur, Amjad Ali, Parnaz Mortazavi, Muhammad Tanveer Altaf, Muhammed Tatar, Muhammad Azhar Nadeem, Bojan Jocković, Velimir Mladenov, Sotirios Fragkostefanakis, Yong Suk Chung, Faheem Shehzad Baloch

Turkish Journal of Agriculture and Forestry

Bread wheat is a globally vital crop, sustaining millions and contributing to food security. The present study investigated the molecular characterization of 60 bread wheat accessions, using 12 interprimer binding site (iPBS) retrotransposon markers, which yielded a total of 260 distinct bands. Out of the 260 bands, 42 were monomorphic while the remaining 218 (83.84%) were polymorphic, with polymorphism information content values ranging from 0.38 to 0.45. Genetic diversity indices, including Shannon’s information index (I = 0.01–0.53), effective number of alleles (Ne = 1.00–1.63), gene diversity (He = 0.0037–0.36), and marker index (MI = 0.31– 0.51), revealed moderate variability across …

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The Status Of Agritourism In Bosnia And Herzegovina, Nerma Čolaković-Prguda, Jasna Hasanbegović, Irma Đidelija Čolaković, Lejla Škaljić, Nuray Demi̇r Aug 2025

The Status Of Agritourism In Bosnia And Herzegovina, Nerma Čolaković-Prguda, Jasna Hasanbegović, Irma Đidelija Čolaković, Lejla Škaljić, Nuray Demi̇r

Turkish Journal of Agriculture and Forestry

Agritourism in Bosnia and Herzegovina has a lot of potential benefit for economic growth and sustainable development in rural regions, as it incorporates local culture and natural beauty into the tourism offerings of the region. Tourism creates opportunities to diversify the economy, retain traditions, improve local income, and protect natural resources. This study covered Međugorje, Ilijaš, Rostovo, Vlašić, Bosanska Krupa, Neum, Olovo, Gornji Vakuf, Sarajevo, and Donji Vakuf. Agritourism can provide authentic experiences like learning about traditional agriculture, fruit harvesting, tasting local products, and environmental preservation in destinations like Međugorje and Neum. Ilijaš and Gornji Vakuf have potential in organic …

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Newhouse Impact Magazine 2025, Newhouse School Aug 2025

Newhouse Impact Magazine 2025, Newhouse School

Newhouse Impact Magazine

Showcasing the research and creative work of faculty, staff and students at the Newhouse School

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Cannabis Chemist, Mushroom Explorer And Mentor Leaves Ole Miss Smiling, Marisa C. Atkinson Aug 2025

Cannabis Chemist, Mushroom Explorer And Mentor Leaves Ole Miss Smiling, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – After more than 30 years of teaching and research at the University of Mississippi, and more than five decades overall, pharmacy professor Samir Ross is hanging up his lab coat and retiring.

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Perceptions Of Pain And Benzodiazepine Use Interrelations: A Qualitative Study, Emma Carnes Lape Aug 2025

Perceptions Of Pain And Benzodiazepine Use Interrelations: A Qualitative Study, Emma Carnes Lape

Dissertations - ALL

Growing concern and research attention have focused on potential harms associated with widespread use of benzodiazepine (BZD) medications. Individuals with chronic pain bear a disproportionate burden, characterized by higher rates of BZD prescriptions, longer-term use, and increased dependence compared to the general population. Although theory and emerging evidence suggest that pain may play a role in the maintenance of BZD use, there is no extant data describing how individuals perceive interrelations between their pain and BZD use. The aims of the present study were to conduct a thematic analysis of interview data regarding perceptions of interrelationships between pain and BZD …

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Characterization Of The Molecular Mechanisms Of Noise Stress On Developmental Plasticity In Gryllus Bimaculatus & Co-Teaching And Peer-Led Team Learning In Undergraduate Introductory Biology Courses Toward Expanding Participation In Stem For All, Takunda Maisva Aug 2025

Characterization Of The Molecular Mechanisms Of Noise Stress On Developmental Plasticity In Gryllus Bimaculatus & Co-Teaching And Peer-Led Team Learning In Undergraduate Introductory Biology Courses Toward Expanding Participation In Stem For All, Takunda Maisva

Dissertations - ALL

As part of my training as a Discipline Based Education Researcher (DBER), I gained human subjects educational research experience as well as traditional biology research experience in the laboratory setting. This dissertation explores both my biology education research and traditional developmental biological research. The first and second projects focus on biology education research, examining how Peer-Led Team Learning (PLTL) and modifying introductory biology course instructional design can influence student outcomes in undergraduate Biology education. The third project examines how anthropogenic noise affects the developmental biology of the two-spotted field cricket Gryllus bimaculatus using a genetic approach. Peer-Led Team Learning (PLTL) …

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Distributed Sovereignty: Law, Community, And Authority In The Political Theories Of Al-Māwardī, Al-Juwaynī, And Al-Fārābī, Ahmet Çelik Aug 2025

Distributed Sovereignty: Law, Community, And Authority In The Political Theories Of Al-Māwardī, Al-Juwaynī, And Al-Fārābī, Ahmet Çelik

Dissertations - ALL

ABSTRACT This dissertation examines the concept of sovereignty in classical Islamic political thought through a comparative analysis of three major thinkers—al-Māwardī (d. 450/1058), al-Juwaynī (d. 478/1085), and al-Fārābī (d. 339/950)—each representing a distinct epistemic tradition: jurisprudence (fiqh), speculative theology (kalām), and philosophy (falsafa). Employing a conceptual and textual methodology, the study reconstructs a theory of distributed sovereignty in Islamic thought, in which political authority is not centralized in a singular sovereign but dispersed across three interrelated domains: legitimate authority, lawgiving, and governance. Drawing on primary texts—including al-Aḥkām al-Sulṭāniyya, Tashīl al-Naẓar, Ghiyāth al-Umam, al-Madīna al-Fāḍila, al-Siyāsa al-Madanīyya, Kitāb al-Milla, and Iḥṣāʾ …

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Wbd-Yolo-Am: Yolov8 With Attention Module And Iot-Based Wild Boar Detection And Deterrence System For Safeguarding Small Millets, Aditya Joshi, Neha Pandey, Manoj Diwakar, Prabhishek Singh, Achyut Shankar, Fayez Alqahtani Aug 2025

Wbd-Yolo-Am: Yolov8 With Attention Module And Iot-Based Wild Boar Detection And Deterrence System For Safeguarding Small Millets, Aditya Joshi, Neha Pandey, Manoj Diwakar, Prabhishek Singh, Achyut Shankar, Fayez Alqahtani

Turkish Journal of Agriculture and Forestry

Small millets are traditional and climate-resilient food crops that can grow in adverse weather conditions. Animal intrusion, specifically from wild boars, is a main threat to the production of small millets, which reduces interest in the cultivation of small millets and affects farmers’ incomes. To address the problem of wild boar attack on agriculture land, an improved YOLOv8 is proposed, with an attention module based on WBD-YOLO-AM and that works from the collection of data, its preprocessing, attention mechanism to improve the feature maps, training then building the model, after that the models hyperparameter are tuned to boost the performance …

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Characteristics And Effectiveness Of Premarital Thalassaemia Educational Interventions Worldwide: A Scoping Review, Maisarah N. Anwar, Nik Nairan Abdullah, Dalila Roslan, Aimi N.M. Ruzlin Aug 2025

Characteristics And Effectiveness Of Premarital Thalassaemia Educational Interventions Worldwide: A Scoping Review, Maisarah N. Anwar, Nik Nairan Abdullah, Dalila Roslan, Aimi N.M. Ruzlin

Sultan Qaboos University Medical Journal

Thalassaemia, a hereditary blood disorder, remains under-recognised due to limited awareness, particularly among young people. This scoping review aimed to evaluate the characteristics and effectiveness of premarital thalassaemia educational interventions globally. Following PRISMA-ScR guidelines, six databases were searched for English-language studies targeting adolescents and young adults. Eight studies met the inclusion criteria, and data were extracted using a standardised form adapted from the Joanna Briggs Institute, focusing on intervention characteristics, outcomes and key findings. Most studies involved school students and young adults from culturally diverse, resource-limited settings. The interventions—traditional, technology-based or culturally adapted—consistently improved knowledge (P < 0.001). However, behavioural outcomes, such as increased uptake of screening, were inconsistent. While educational strategies enhanced knowledge effectively, socio-cultural barriers limited the translation into behavioural changes. These findings support the need for future interventions to integrate behavioural change theories, leverage digital tools and address cultural sensitivities to improve their overall impact.

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California Utility-Scale Solar Energy Land Use Impacts On Species And Ecosystems, Ingrid Salazar Aug 2025

California Utility-Scale Solar Energy Land Use Impacts On Species And Ecosystems, Ingrid Salazar

Master's Theses

Utility-scale solar energy (USSE), defined as projects of at least 1 megawatt, is rapidly expanding in California, which generated 37.5% of its electricity from renewables in 2023, with 24% coming from solar. While USSE supports decarbonization, it can also cause environmental harm, including biodiversity loss, habitat fragmentation, and land conversion. This study uses ArcGIS Pro 3.4.0 and public environmental data to analyze the spatial distribution of USSE projects, land use changes from 2013 to 2023, and occurrences of at-risk species across California’s bioregions. USSE development is heavily concentrated in the Mojave Desert, San Joaquin Valley, and Colorado Desert, which are …

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Engineering Protein Linkers For Optimized Telsam-Darpin Fusion And Crystallization With Electric Field-Based Polymer Orientation, Maria Jose Pedroza Romo Aug 2025

Engineering Protein Linkers For Optimized Telsam-Darpin Fusion And Crystallization With Electric Field-Based Polymer Orientation, Maria Jose Pedroza Romo

Theses and Dissertations

Fusing a variant of the sterile alpha motif domain of the human translocation ETS leukemia protein (TELSAM) to a protein of interest significantly enhances crystallization and diffraction quality. TELSAM is a pH-dependent, polymer-forming crystallization chaperone that, when covalently fused to a protein, forms a well-ordered crystal lattice. However, the success of this method depends on two factors: 1) the design of the linker connecting TELSAM to the target protein, which influences both crystal packing and target orientation, and 2) the prevention of TELSAM polymer flipping, a phenomenon that disrupts lattice periodicity and impairs structure determination. To address the first challenge, …

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Prediction Of Drug-Induced Cardiotoxicity Using Machine Learning Analysis Of Hipsc-Cm Contractile Profiles, Anthony Allan Watt Aug 2025

Prediction Of Drug-Induced Cardiotoxicity Using Machine Learning Analysis Of Hipsc-Cm Contractile Profiles, Anthony Allan Watt

Theses - ALL

Drug-induced cardiotoxicity remains a critical concern in pharmaceutical development as failed drug candidates result in lost time and resources that could be better spent on viable candidates. We believe that a robust in vitro model that accurately captures human cardiac physiology is an applicable model for examining drug candidates. In addition to those models, there is a need for quick and effective predictive models to analyze data obtained from the model to classify drugs based on their potential for cardiotoxicity. In this study, we conduct a functional analysis of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) and pass the data collected …

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Fertile, Social, Dangerous, Sacred, Gift, And System: Religion, Salt City Harvest Farm, And The Future Of Human Shit, Sarah Elizabeth Nahar Aug 2025

Fertile, Social, Dangerous, Sacred, Gift, And System: Religion, Salt City Harvest Farm, And The Future Of Human Shit, Sarah Elizabeth Nahar

Dissertations - ALL

Shit, the taboo term for the human excreta that exits the anus, can be understood as sacred. Shitting, the vulgar verb to describe the act of discarding solid excreta, can likewise be understood as religious ritual activity. This counters the Dominant Social Paradigm (DSP) in the United States (US) of the placement of shit as profane, and shitting as unceremonial. An aim of this dissertation is to reclaim the word shit from the realm of what the DSP has rendered invisible and unspeakable, and spark rigorous academic discussion about it in the context of Religion and Environmental Studies. The DSP …

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Oxidation Resistance And Osmotic Energy Harvesting Applications Of Reduced Graphene Oxide Forward Osmosis Membranes, Michael Appiah-Kubi Aug 2025

Oxidation Resistance And Osmotic Energy Harvesting Applications Of Reduced Graphene Oxide Forward Osmosis Membranes, Michael Appiah-Kubi

Theses and Dissertations

Reduced graphene oxide (RGO) forward osmosis (FO) membranes have emerged as promising candidates for efficient wastewater management and osmotic energy harvesting, due to their enhanced chemical stability and superior FO performance for low-energy waste brine treatments, such as volume reduction of oxidative chromium brine for cost-effective disposal. This dissertation first examines the oxidation resistance of RGO forward osmosis membranes against chromate Cr (VI). Our findings reveal that both the water flux and the reverse salt flux of RGO membranes are suppressed, accompanying an enhanced reverse flux selectivity after exposure to an acidic medium of Cr (VI) (pH 2.0-7.0). Meanwhile, the …

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Assessment Of Bat Species (Mammalia: Chiroptera) In Canubas Cave, Kibawe, Bukidnon, Philippines, Jurriel Mari D. Alce, Jasmine Rouida M. Abenes, Leo Gabriel Cervantes, Matthew Eli K. Llacer, Von Zhyrus P. Oche, Ian Jay P. Saldo, Jhovel Roy D. Calo Aug 2025

Assessment Of Bat Species (Mammalia: Chiroptera) In Canubas Cave, Kibawe, Bukidnon, Philippines, Jurriel Mari D. Alce, Jasmine Rouida M. Abenes, Leo Gabriel Cervantes, Matthew Eli K. Llacer, Von Zhyrus P. Oche, Ian Jay P. Saldo, Jhovel Roy D. Calo

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Bats, flying mammals, are essential to ecosystems, playing vital roles in pollination, seed dispersal, and insect control. Despite their ecological importance, no prior bat research exists for Canubas Cave, Kibawe, Bukidnon. This study aimed to assess the bat species at the site, documenting their morphometric data, diversity and richness indices, and conservation statuses. A purposive sampling design was implemented by setting up mist nets inside and outside the cave. A total of 13 individuals were identified, comprising three species from two families: Rousettus amplexicaudatus and Eonycteris spelaea (family Pteropodidae, fruit bats), and Miniopterus schreibersii (family Miniopteridae, bent-winged bats). Based on …

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Milkfish (Chanos Chanos) Bones As A Biosorbent For Mercury (Ii) Contamination In Water, Seth Uriel K. Neri, Ethan Kyle Mangao, Christian Kevin F. Redoblado, Anthony Cesar Y. Ponce, Roby Boy P. Riego, Jupiter O. Yap Aug 2025

Milkfish (Chanos Chanos) Bones As A Biosorbent For Mercury (Ii) Contamination In Water, Seth Uriel K. Neri, Ethan Kyle Mangao, Christian Kevin F. Redoblado, Anthony Cesar Y. Ponce, Roby Boy P. Riego, Jupiter O. Yap

Sinaya: A Philippine Journal for Senior High School Teachers and Students

Heavy metals, such as mercury contamination in water sources are a major environmental and public health issue in many countries. Traditional methods for removing heavy metals from water are effective but often costly and unsustainable and may produce secondary waste. Recent trends favor more sustainable alternatives, such as biosorbents in treating water with heavy metals. Milkfish (Chanos chanos), a common fish in the Philippines, contains hydroxyapatite in the bones that can bind with heavy metals through physical and chemical adsorption mechanisms. This study aims to evaluate the mercury (II) reduction capacity of biosorbent derived from milkfish bones in water, specifically …

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Muscarinic Acetylcholine Receptor 1: Implications For Precision Medicine And Rett Syndrome Therapeutics, Mackenzie Smith Aug 2025

Muscarinic Acetylcholine Receptor 1: Implications For Precision Medicine And Rett Syndrome Therapeutics, Mackenzie Smith

Dissertations

Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by mutations in the gene coding for methyl-CpG binding protein 2 (MeCP2). Currently, there is no cure for RTT and few effective treatment options to address the social, cognitive, motor, and respiratory symptoms that patients face. With the goal of identifying novel targets, our lab performed RNA-sequencing experiments in human autopsy samples and found decreased levels of the M1 muscarinic acetylcholine receptor. We have established that potentiation of this receptor in a Mecp2+/- mouse model of RTT rescues social, cognitive, and respiratory phenotypes, providing support for using drugs that act on …

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Biophysical Effects Of Altered Myosin Binding Protein Stoichiometry In Atrial Myofilaments, Kelly N. Araujo Aug 2025

Biophysical Effects Of Altered Myosin Binding Protein Stoichiometry In Atrial Myofilaments, Kelly N. Araujo

Dissertations

Cardiomyopathies, such as hypertrophic and dilated subtypes, are leading causes of heart failure and are often driven by genetic mutations that disrupt the structure and function of the cardiac sarcomere. While much of the research has focused on ventricular involvement, the role of atrial sarcomere dysfunction remains unexplored. The regulation of contractile function by sarcomeric proteins in the atria remains poorly understood, especially the impact of protein stoichiometry among myosin binding proteins. Cardiac myosin binding protein-C (cMyBP-C) and its atrial paralog, myosin binding protein H-like (MyBP-HL), have been shown to have a stoichiometric relationship within the atrial sarcomere. These two …

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Holographic Scaling And Cosmological Correlators, He Li Aug 2025

Holographic Scaling And Cosmological Correlators, He Li

Dissertations - ALL

It is well-established that the two-point correlator of a scalar field in AdS follows either of two scaling laws, ∆± =d/2 ± ν, where ν =Sqrt((d/2)^2+ m^2) is a function of the scalar bulk mass. The transition between these two scalings occurs in the renormalization group evolution from the UV to the IR of a dual 4D conformal theory deformed by a relevant double-trace deformation. In this thesis, we identify a new holographic scaling law, ∆UV = ν, in the context of the AdS/CFT correspondence where there exists a UV cutoff brane. Specifically, when ν > 1, the ∆− scaling that …

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A Multimodal Approach To Assess A Liposomal Carrier’S Biodistribution, Stability, And Clearance, Cayla A Wood, Claire E Jones, Ananthakrishnan Soundaram Jeevarathinam, Riley Watson, Sangheon Han, Jennifer Meyer, Konstantin V Sokolov, Richard R Bouchard Aug 2025

A Multimodal Approach To Assess A Liposomal Carrier’S Biodistribution, Stability, And Clearance, Cayla A Wood, Claire E Jones, Ananthakrishnan Soundaram Jeevarathinam, Riley Watson, Sangheon Han, Jennifer Meyer, Konstantin V Sokolov, Richard R Bouchard

Faculty, Staff and Student Publications

Liposomal carriers, used for site-specific drug delivery, are being investigated for diagnostic approaches by replacing the therapeutic with an imaging contrast agent, exploring potential for selective treatment planning. There remains a critical need to improve in vivo assessment of biodistribution, stability, and clearance kinetics of liposomal carriers. This pilot study presents a multimodal approach in which liposome-encapsulated J-aggregated indocyanine green (ICG) dye (Lipo-JICG) is imaged with high spatial resolution using both in vivo photoacoustic (PA) imaging, to assess the absorbance characteristics of JICG and monomeric ICG, and ex vivo cryofluorescence tomography (CFT), to measure ICG fluorescence. An in vitro assay …

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Prolonging Lung Cancer Response To Egfr Inhibition By Targeting The Selective Advantage Of Resistant Cells, Lisa Brunet, David Alexandre, Jiyoung Lee, Maria Del Mar Blanquer-Rosselló, David Bracquemond, Alexis Guernet, Houssein Chhouri, Mathilde Goupil, Zoulika Kherrouche, Arnaud Arabo, Maicol Mancini, Dorthe Cartier, Shen Yao, David Godefroy, Julie Dehedin, Jian-Rong Li, Céline Duparc, Philippe Jamme, Audrey Vinchent, Caroline Bérard, David Tulasne, Sabrina Arena, Alberto Bardelli, Chao Cheng, Byoung Chul Cho, Olivier Wurtz, Cédric Coulouarn, Antonio Maraver, Stuart A Aaronson, Alexis B Cortot, Youssef Anouar, Luca Grumolato Aug 2025

Prolonging Lung Cancer Response To Egfr Inhibition By Targeting The Selective Advantage Of Resistant Cells, Lisa Brunet, David Alexandre, Jiyoung Lee, Maria Del Mar Blanquer-Rosselló, David Bracquemond, Alexis Guernet, Houssein Chhouri, Mathilde Goupil, Zoulika Kherrouche, Arnaud Arabo, Maicol Mancini, Dorthe Cartier, Shen Yao, David Godefroy, Julie Dehedin, Jian-Rong Li, Céline Duparc, Philippe Jamme, Audrey Vinchent, Caroline Bérard, David Tulasne, Sabrina Arena, Alberto Bardelli, Chao Cheng, Byoung Chul Cho, Olivier Wurtz, Cédric Coulouarn, Antonio Maraver, Stuart A Aaronson, Alexis B Cortot, Youssef Anouar, Luca Grumolato

Faculty, Staff and Students Publications

Non-small cell lung cancers (NSCLCs) treated with tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) almost invariably relapse in the long term, due to the emergence of subpopulations of resistant cells. Through a DNA barcoding approach, we show that the clinically approved drug sorafenib specifically abolishes the selective advantage of EGFR-TKI-resistant cells, while preserving the response of EGFR-TKI-sensitive cells. Sorafenib is active against multiple mechanisms of resistance/tolerance to EGFR-TKIs and its effects depend on early inhibition of MAPK-interacting kinase (MKNK) activity and signal transducer and activator of transcription 3 (STAT3) phosphorylation, and later down-regulation of MCL1 and …

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La Maternidad Desmitificada En El Matrimonio De Los Peces Rojos De Guadalupe Nettel Y Casas Vacías De Brenda Navarro, Luis Alberto De Loera Aug 2025

La Maternidad Desmitificada En El Matrimonio De Los Peces Rojos De Guadalupe Nettel Y Casas Vacías De Brenda Navarro, Luis Alberto De Loera

Cuaderna Vía

No abstract provided.

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Parole, Parole, Parole, Margarita V. Salazar Canseco, Noé Pozos Aug 2025

Parole, Parole, Parole, Margarita V. Salazar Canseco, Noé Pozos

Cuaderna Vía

No abstract provided.

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