Digital Commons Network^™

Programs Committee Agenda 3/15/22, Angela Brock

Programs Committee (PC)

No abstract provided.

California Constitutional Law: Privacy, David A. Carrillo, Stephen M. Duvernay, Rodolfo E. Rivera Aquino, Brandon V. Stracener

San Diego Law Review

California voters passed Proposition 11 (the Privacy Initiative) in 1972, amending the state constitution to include a fundamental right to privacy. The ballot arguments for Proposition 11 expressed the voters’ intent to set a high bar for invaders to justify privacy invasions: requiring a compelling public need. For the first twenty years of the new constitutional privacy right’s existence, courts required invaders of individual privacy to meet the compelling public need standard to justify such invasions.

Yet the courts reversed course in 1994, abandoned the compelling public need standard, and have since applied a standard that perverts the electorate’s intent: …

Drosophila Functional Screening Of De Novo Variants In Autism Uncovers Damaging Variants And Facilitates Discovery Of Rare Neurodevelopmental Diseases, Paul C Marcogliese, Samantha L Deal, Jonathan Andrews, J Michael Harnish, V Hemanjani Bhavana, Hillary K Graves, Sharayu Jangam, Xi Luo, Ning Liu, Danqing Bei, Yu-Hsin Chao, Brooke Hull, Pei-Tseng Lee, Hongling Pan, Pradnya Bhadane, Mei-Chu Huang, Colleen M Longley, Hsiao-Tuan Chao, Hyung-Lok Chung, Nele A Haelterman, Oguz Kanca, Sathiya N Manivannan, Linda Z Rossetti, Ryan J German, Amanda Gerard, Eva Maria Christina Schwaibold, Sarah Fehr, Renzo Guerrini, Annalisa Vetro, Eleina England, Chaya N Murali, Tahsin Stefan Barakat, Marieke F Van Dooren, Martina Wilke, Marjon Van Slegtenhorst, Gaetan Lesca, Isabelle Sabatier, Nicolas Chatron, Catherine A Brownstein, Jill A Madden, Pankaj B Agrawal, Boris Keren, Thomas Courtin, Laurence Perrin, Melanie Brugger, Timo Roser, Steffen Leiz, Frederic Tran Mau-Them, Julian Delanne, Elena Sukarova-Angelovska, Slavica Trajkova, Erik Rosenhahn, Vincent Strehlow, Konrad Platzer, Roberto Keller, Lisa Pavinato, Alfredo Brusco, Jill A Rosenfeld, Ronit Marom, Michael F Wangler, Shinya Yamamoto

Duncan NRI Faculty and Staff Publications

Individuals with autism spectrum disorder (ASD) exhibit an increased burden of de novo mutations (DNMs) in a broadening range of genes. While these studies have implicated hundreds of genes in ASD pathogenesis, which DNMs cause functional consequences in vivo remains unclear. We functionally test the effects of ASD missense DNMs using Drosophila through "humanization" rescue and overexpression-based strategies. We examine 79 ASD variants in 74 genes identified in the Simons Simplex Collection and find 38% of them to cause functional alterations. Moreover, we identify GLRA2 as the cause of a spectrum of neurodevelopmental phenotypes beyond ASD in 13 previously undiagnosed …

“Goodbye, My Friencels”: An Analysis Of Incel Suicide Posts, Sarah E. Daly, Albina Laskovsov

Qualitative Criminology (QC)

While an increasing number of researchers, non-profit organizations, and law enforcement agencies have expressed growing concern about the relationship between involuntary celibates (i.e., incels) and violence, no research to date has examined the potential for suicide and self-harm among men who call themselves incels. This study examines suicide posts shared to incel sub-Reddits that were collected by u/IncelGraveyard (N=80). The posts reveal that the notes discuss six subordinate themes, including the method of their planned attempt, the ways they used the internet, the online incel community, failed alternatives and coping, the effects of their suicide on others, and the afterlife. …

The Life History Of Drosophila Sperm Involves Molecular Continuity Between Male And Female Reproductive Tracts, Erin L. Mccullough, Emma Whittington, Akanksha Singh, Scott Pitnick, Mariana F. Wolfner, Steve Dorus

Biology

Interactions between sperm and the female reproductive tract (FRT) are critical to reproductive success and yet are poorly understood. Because sperm complete their functional maturation within the FRT, the life history of sperm is likely to include a molecular “hand-off” from males to females. Although such intersexual molecular continuity is likely to be widespread among all internally fertilizing species, the identity and extent of female contributions are largely unknown. We combined semiquantitative proteomics with sex-specific isotopic labeling to catalog the posttesticular life history of the sperm proteome and determine the extent of molecular continuity between male and FRTs. We show …

Suppression Of Pi3k Signaling Is Linked To Autophagy Activation And The Spatiotemporal Induction Of The Lens Organelle Free Zone, Rifah Gheyas, Ramon Ortega-Alvarez, Daniel Chauss, Marc Kantorow, A. Menko

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The terminal steps of lens cell differentiation require elimination of all organelles to create a central Organelle Free Zone (OFZ) that is required for lens function of focusing images on the retina. Previous studies show that the spatiotemporal elimination of these organelles during development is autophagy-dependent. We now show that the inhibition of PI3K signaling in lens organ culture results in the premature induction of autophagy within 24 h, including a significant increase in LAMP1+ lysosomes, and the removal of lens organelles from the center of the lens. Specific inhibition of just the PI3K/Akt signaling axis was directly linked to …

Repurposing Lansoprazole And Posaconazole To Treat Leishmaniasis: Integration Of In Vitro Testing, Pharmacological Corroboration, And Mechanisms Of Action, Yash Gupta, Steven Goicoechea, Jesus G. Romero, Raman Mathur, Thomas R. Caulfield, Daniel P. Becker, Ravi Durvasula, Prakasha Kempaiah

Chemistry: Faculty Publications and Other Works

Leishmaniasis remains a serious public health problem in many tropical regions of the world. Among neglected tropical diseases, the mortality rate of leishmaniasis is second only to malaria. All currently approved therapeutics have toxic side effects and face rapidly increasing resistance. To identify existing drugs with antileishmanial activity and predict the mechanism of action, we designed a drug-discovery pipeline utilizing both in-silico and in-vitro methods. First, we screened compounds from the Selleckchem Bio-Active Compound Library containing ~1622 FDA-approved drugs and narrowed these down to 96 candidates based on data mining for possible anti-parasitic properties. Next, we completed preliminary in-vitro testing …

Ucc Minutes 3/15/22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Anatomic Considerations Of Perinasal Musculature For Improved Dental Show During Smile In Facial Synkinesis, Laura T. Hetzler, Marcus Hershey, Todd Lambert, Jason Mussell, Lee Mcdaniel, Sara Macdowell

School of Medicine Faculty Publications

Introduction: There is an anatomic explanation for upper lip and midfacial tethering resulting in lack of motion in facial synkinesis. Objective: To measure the effect of perinasal chemodenervation on dental show in the synkinetic population and clarify the anatomic relationship of perinasal musculature. Methods: Literature search was performed on anatomy of the perinasal modiolus, and anatomic evaluation was performed through human anatomic specimen dissection. Photographic outcomes were observed in synkinetic patients receiving chemodenervation to smile antagonists with and without perinasal muscle injections and assessed through naive observer survey. Retrospective outcomes for all patients receiving perinasal chemodenervation was collected utilizing Facial …

Modeling Cyanobacteria Vertical Migration, Corina Christina Mae Overman, Scott A. Wells

Civil and Environmental Engineering Faculty Publications and Presentations

Cyanobacteria often cause harmful algal blooms and release toxic substances that can harm humans and animals. Accurately modeling these phytoplankton is a step towards predicting, preventing, and controlling such blooms. Certain cyanobacteria species are known to migrate vertically in the water column on a daily cycle. Capturing this behavior is one aspect of modeling their dynamics. Previous studies on modeling cyanobacterial vertical migration are reviewed and summarized. Several models of cyanobacteria vertical movement are tested using data from field studies. These models are applied using both continuum and particle-tracking frameworks. Models range in complexity from simple functions of time to …

Miami University, Oxford, Ohio, With Miami Men, Circa 1920

Documents

46-page prospectus titled "With Miami Men" published by Miami University in Oxford, Ohio, circa 1920.

Goodwyn Institute, Memphis, Announcement, 1931

Documents

Announcement for the 25th season of the Goodwyn Institute, Memphis, Tennessee, with the program of lectures for 1931-1932.

The Hybridization Of Home: Establishing Place Between The Garrison And The Wilderness In Mary Rowlandson's (1682) Captivity Narrative, Brooke M. Weltch

USF Tampa Graduate Theses and Dissertations

Scholarship surrounding captivity narratives long agrees that the psychological and philosophical beliefs of their authors lend insight into the contemporaneous hegemonic power structures through literary forms. Looking beyond these forms to the places they describe, however, illustrates the extent to which cultural perceptions infiltrate even the mere relationships that individuals have with their environment as well as the material structures surrounding them. I focus the role of place in Mary Rowlandson’s narrative, The Soveraignty and Goodness of God (1682). I argue that Rowlandson forms an attachment with the wigwam on account of her traumatic experiences while in captivity. Her displacement …

Sars-Cov-2 Reinfection Prevents Acute Respiratory Disease In Syrian Hamsters But Not Replication In The Upper Respiratory Tract, Frederick Hansen, Kimberly Meade-White, Chad Clancy, R Rosenke, Atsushi Okumura, David W. Hawman, F Feldmann, Benjamin Kaza, Michael A. Jarvis, K Rosenke, H Feldmann

School of Biomedical Sciences

No abstract provided.

Maternal Low Protein Diet And Fetal Programming Of Lean Type 2 Diabetes, Vidyadharan Alukkal Vipin, Chellakkan Selvanesan Blesson, Chandra Yallampalli

Faculty, Staff and Students Publications

Maternal nutrition is found to be the key factor that determines fetal health in utero and metabolic health during adulthood. Metabolic diseases have been primarily attributed to impaired maternal nutrition during pregnancy, and impaired nutrition has been an immense issue across the globe. In recent years, type 2 diabetes (T2D) has reached epidemic proportion and is a severe public health problem in many countries. Although plenty of research has already been conducted to tackle T2D which is associated with obesity, little is known regarding the etiology and pathophysiology of lean T2D, a variant of T2D. Recent studies have focused on …

L-Plastin Enhances Nlrp3 Inflammasome Assembly And Bleomycin-Induced Lung Fibrosis, Hemant Joshi, Alison Almgren-Bell, Edgar P Anaya, Elizabeth M Todd, Steven J Van Dyken, Anushree Seth, Katherine M Mcintire, Srikanth Singamaneni, Fayyaz Sutterwala, Sharon C Morley

2020-Current year OA Pubs

Macrophage adhesion and stretching have been shown to induce interleukin (IL)-1β production, but the mechanism of this mechanotransduction remains unclear. Here we specify the molecular link between mechanical tension on tissue-resident macrophages and activation of the NLRP3 inflammasome, which governs IL-1β production. NLRP3 activation enhances antimicrobial defense, but excessive NLRP3 activity causes inflammatory tissue damage in conditions such as pulmonary fibrosis and acute respiratory distress syndrome. We find that the actin-bundling protein L-plastin (LPL) significantly enhances NLRP3 assembly. Specifically, LPL enables apoptosis-associated speck-like protein containing a caspase activation and recruitment domain (ASC) oligomerization during NLRP3 assembly by stabilizing ASC interactions …

Plasticity In Female Incubation Behaviour Mitigates Effects Of Experimentally Increased Nestbox Temperature On House Wren Nestling Growth And Survival, Paige Anne Farchmin

Theses and Dissertations

In recent years, temperatures have increased globally, and by different amounts locally. As local climates change and temperatures increase, nestlings from a variety of bird species are exposed to the threat of increased oxidative stress, producing adverse effects on growth and survival of offspring. One defence against oxidative stress is to increase the dietary intake of antioxidants. I tested the hypothesis that experimental heating of house wren nests during the incubation period leads to increased oxidative stress in offspring. I predicted that experimental heating of nests would lead to decreased growth and survival of young, but that these negative effects …

Spatiotemporal Patterns Of San Joaquin Kit Foxes And An Urban Canid Guild, Nicole A. Deatherage, Brian L. Cypher, Tory L. Westall, Erica C. Kelly

Western North American Naturalist

The federally endangered and California State–threatened San Joaquin kit fox (Vulpes macrotis mutica) forms an ecological guild with coyotes (Canis latrans), red foxes (V. vulpes), gray foxes (Urocyon cinereoargenteus), and domestic dogs (C. familiaris) in the city of Bakersfield, California, USA. Where these species are sympatric in natural environments, interference competition occurs, resulting in spatiotemporal avoidance or changes in behavior to avoid conflict. We analyzed camera survey data from 2015 to 2019 from 111 1-km2 grid cells throughout Bakersfield to investigate spatial associations between San Joaquin kit foxes and canid …

Presence Of Neotropical Otter (Lontra Longicaudis) At High Elevation Between Watersheds, Juan Pablo Esparza-Carlos, Pablo César Hernández-Romero, Jaime Antonio Escoto Moreno

Western North American Naturalist

The neotropical otter (Lontra longicaudis) is associated with freshwater systems and is generally found at elevations lower than 1500 m asl. Its diet is based on fish and crustaceans. We present 3 photorecords of the neotropical otter at the divide between 2 hydrological basins in the Sierra de Manantlán Biosphere Reserve, Jalisco, México. The photos were taken at an altitude near 2000 m asl, and one of them was >600 m from a water source. The area does not present optimal conditions for the presence of otter since water flows are low, fish are absent, and crustaceans are …

Enhancing The Higher Education Quality With Mooc Penetration: Role Of Policy, Library And Curriculum, Flora Charles Lazarus, Rajneesh Suryasen

Library Philosophy and Practice (e-journal)

The governments of emerging economies have realized the potential of MOOCs for enhancing the quality of higher education, but still, the MOOC penetration is very low in countries like India. This study explores the issues relating to MOOC integration and attempts to identify the key drivers for the adoption of MOOC based curriculum. 'Integration into Curriculum', 'MOOC Services of Academic Library', and 'MHRD Policy and Support' are identified as the key drivers for increasing the MOOC Penetration. The higher the level of MOOC penetration the greater would be the improvement in the quality of higher education. The practical implications for …

Untitled

Exile

No abstract provided.

Determinants Of Food Selection By Bivalve Larvae, Maria Rosa, Diane K. Padilla

Biology Faculty Publications

Selection of food particles for consumption by larvae impacts nutritional gain needed for growth, development, and metamorphosis. Past work has suggested that molluscan larvae are capable of collecting food within a narrow size range. Recent studies have found evidence of size-independent food selection in molluscan larvae, but relatively little is known about the characteristics of particles that larvae preferentially capture. Therefore, we conducted experiments with the larvae of two mussels, Mytilus trossulus and Mytilus edulis, to determine whether they are selective feeders, and if so, whether we could determine the characteristics of particles selected as food. We fed larvae microalgae …

Cseas Weekly Bulletin (March 14, 2022), Center For Southeast Asian Studies

CSEAS Bulletin

No abstract provided.

Adam Smith And Economic Development In Theory And Practice: A Rejection Of The Stadial Model?, Maria Pia Paganelli

Economics Faculty Research

Adam Smith allegedly offers a model of economic development in both his Lectures on Jurisprudence and the Wealth of Nations - the so-called four stages of development model. The model presents a linear unfolding view of economic development from primitive to advanced stages. But Smith's own historical examples systematically contradict this model. I thus question whether Adam Smith actually endorses and uses the four stages model of development to illustrate development and suggest that if he does, he does it to discredit it instead. For Smith, history teaches that development is more accidental than fitting deterministic models.

Faculty Senate Executive Committee Agenda, March 14, 2022, Utah State University

Faculty Senate & Faculty Senate Executive Committee

Agenda

• Call to Order- Boyd Edwards, Approval of Minutes February 14, 2022
• University Business- Noelle Cockett, President | Frank Galey, Provost
• Information- Paul Barr, Education Policies Committee March 3, 2022
• Reports

Honorary Degrees and Awards Annual Report- Noelle Cockett

Professional Responsibilities and Procedures Annual Report- Scott Hunsaker

• Old Business
• New Business-

Faculty Senate Calendar 2022-2023- Boyd Edwards

DivestUSU- Doug Ramsey | Cristina Chirvasa

The Magic Of Being Among Gorillas In Rwanda, Eric Bernthal

Tales of WellBeing

WBI Board member, Rick Bernthal, describes his visit to Rwanda and the Virunga Mountains to see Mountain Gorillas.

The Rise And Fall Of A Real Klutz, Jerry Zezima

Erma Bombeck Writers' Workshop Blog

Being a grandfather has put a bounce in my step, frequently followed by a stubbed toe, but I really got a jump on fun when my granddaughters invited me to join them on their new trampoline.

The Utah Statesman, March 14, 2022, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Role Of Chemical Cues In Host Susceptibility To Fish-Parasitic Gnathiid Isopods., Clayton M. Vondriska

Student Theses and Dissertations

Parasitism is one of the most common lifestyle strategies. Ectoparasites must navigate complex environments to find their host and many rely heavily on chemical cues to do so. Gnathiid isopods are common parasites that use chemical cues to find their marine fish hosts. While gnathiids are considered host-generalists, hosts vary in their susceptibility to infestation. However, the mechanisms that mediate differential susceptibility are unknown. Here I used field and laboratory experiments to investigate if the chemo-attractiveness of hosts explains differences in susceptibility of Caribbean reef fishes to infestation by a common Caribbean gnathiid isopod, Gnathia marleyi. While G. marleyi can …

Executive "Expertise"?: Reviewing And Reconsidering Statutory Requirements In Executive Branch Positions, Russell Spivak

Denver Law Review

The nomination of John Ratcliffe to be the Director of National Intelligence resurfaced debates over Congress’s authority to restrict the President’s ability to nominate certain individuals outside of its “advise and consent” role, given that the Director is statutorily required to have “extensive national security expertise.” While the subject of statutory requirements on executive appointments has been reviewed a handful of times, those discussions focused on whether such restrictions are constitutional. This Article, on the other hand, begins where prior discussions have left off: what positions are subject to statutory requirements? In answering this question, this Article identifies the different …