Digital Commons Network^™

Design And Construction Of A Biogas Burner, David O. Obada

Palestine Technical University Research Journal

This paper details the design and fabrication of a burner system, operating on biogas, for use in remote or rural regions of developing countries such as Nigeria. A desirable use for such a system in these areas is domestic cooking, and the burner has been designed with this need in mind, focusing on characteristics such as simplicity, cost effectiveness, efficiency and safety. Mild steel, brass and galvanized pipe sourced locally were selected for the construction. An empirical version of Bernoulli’s theorem was used to derive the flow rate of gas. The different components of the burner design were shown. Also …

Economic Performance Of Organic Vs Conventional Vegetables Production In Gaza Strip, Ahmad Shaban

Palestine Technical University Research Journal

Organic farming has achieved significant growth in developing countries. However, it is still in some areas such as Gaza strip at embryonic stage. Introduction and promotion of organic farming would need more information about economic feasibility of shifting from the existing conventional farms to organic farming system. This is the main aim of this study. Data was collected from 100 randomly selected farmers in southern area of Gaza strip using standard questionnaire. Additional focus group discussions were conducted for further qualitative analyses. Data was also collected from the organic farm of Safe Agriculture Association where vegetables are organically produced and …

Rapd For Assessment Of Thymes Genetic Diversity In Palestine, Raed Alkowni

Palestine Technical University Research Journal

Several thymes species were grown in Palestine and have socio-economical values. Traditionally, morphological features are used for their taxonomy and discrimination. However, these methods fail to provide an accurate for discrimination and authentication, suggesting the use of other method inevitable. In this study, RAPD method was used for genotypes identification and characterization of five most socio-economical Palestinian thymes: Thymus syriacus, Thymus fruticosus, Thymus incanus, Thymus majorana, and Thymus capitatus. Eight out of ten decamer primers were tested for their ability to generate polymorphism from selected thyme species using RAPD-PCR, and the obtained data were analyzed. …

Investigation Of The Presence Of Halogenated Bi-Products Formation In The Drinking Water Network In Tulkarm District / Palestine, Saed Khayat, Basel Natsheh, Tahseen Sayara, Nawaf Abukhalaf, Yamen Hamdan

Palestine Technical University Research Journal

The problem of pollutants in drinking water networks is neglected in many places all over the developing countries. This problem is normally caused by either direct pollution source such as organic carbon, or from the maceration pollutants of network materials. The heavy metals in the network facilities and the DOC from the wastewater leakage on the formation of toxic by-product in the water network and the rate of halogenated hydrocarbons formation in the drinking water network was studied. Results showed that water has the same constituents of pollutants similar to that before its being stored for relatively long periods. The …

Joseph C. Malone Papers, 1925-1999, Joseph C. Malone

Center for Restoration Studies Archives, Manuscripts and Personal Papers Finding Aids

No abstract provided.

Spartan Daily, March 15, 2022, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2022

Volume 158, Issue 20

The Effect Of Task And Environment Constraints On Aquatic Locomotor Behavior: Qualitative Data Analysis, Ernani Xavier Filho, Edison J. Manoel

International Journal of Aquatic Research and Education

Many constraints (environmental, organismic, and task) act on all patterns of motor coordination, although their effects on swimming is less well understood. To this end, we carried out the current study with fifty-six participants, ages ranging from six to twelve years. The experimental tasks were created from the original task in which changes in task speed and environmental context were manipulated. Four aspects in the results were notable: a) a main trend was one of performance with the same developmental status among the tasks; b) when behaviour changed, this occurred due to environmental constraints, leading to more rudimentary patterns of …

Functional Replacement Of Myostatin With Gdf-11 In The Germline Of Mice., Se-Jin Lee, Adam Lehar, Renata Rydzik, Daniel W Youngstrom, Shalender Bhasin, Yewei Liu, Emily L Germain-Lee

Faculty Research 2022

BACKGROUND: Myostatin (MSTN) is a transforming growth factor-ß superfamily member that acts as a major regulator of skeletal muscle mass. GDF-11, which is highly related to MSTN, plays multiple roles during embryonic development, including regulating development of the axial skeleton, kidneys, nervous system, and pancreas. As MSTN and GDF-11 share a high degree of amino acid sequence identity, behave virtually identically in cell culture assays, and utilize similar regulatory and signaling components, a critical question is whether their distinct biological functions result from inherent differences in their abilities to interact with specific regulatory and signaling components or whether their distinct …

Divergent Metabolic Effects Of Metformin Merge To Enhance Eicosapentaenoic Acid Metabolism And Inhibit Ovarian Cancer In Vivo, Mary P. Udumula, Laila M. Poisson, Indrani Datta, Nivedita Tiwari, Seongho Kim, Jasdeep Chinna-Shankar, Ghassan Allo, Sharif Sakr, Miriana Hijaz, Adnan R. Munkarah, Shailendra Giri, Ramandeep Rattan

Obstetrics, Gynecology and Women's Health Services Articles

Metformin is being actively repurposed for the treatment of gynecologic malignancies including ovarian cancer. We investigated if metformin induces analogous metabolic changes across ovarian cancer cells. Functional metabolic analysis showed metformin caused an immediate and sustained decrease in oxygen consumption while increasing glycolysis across A2780, C200, and SKOV3ip cell lines. Untargeted metabolomics showed metformin to have differential effects on glycolysis and TCA cycle metabolites, while consistent increased fatty acid oxidation intermediates were observed across the three cell lines. Metabolite set enrichment analysis showed alpha-linolenic/linoleic acid metabolism as being most upregulated. Downstream mediators of the alpha-linolenic/linoleic acid metabolism, eicosapentaenoic acid (EPA) …

Connectivity And Directionality In Estuarine Channel Networks, Matthew Hiatt, Elisabeth A. Addink, Maarten G. Kleinhans

Faculty Publications

No abstract provided.

Robustly Collaborative Projects Funded Through Annual Amc21 Multi-Pi Awards; Lee, Pollock, And Korf Advance Cutting-Edge Research, Mary Ashley Canevaro

Browse All News

No abstract provided.

Programs Committee Approved Programs 3/15/22, Angela Brock

Programs Committee (PC)

No abstract provided.

Mutant Lrrk2 In Lymphocytes Regulates Neurodegeneration Via Il-6 In An Inflammatory Model Of Parkinson's Disease, Elena Kozina, Matthew D. Byrne, Richard Jay Smeyne

Department of Neuroscience Faculty Papers

Mutations in a number of genes contribute to development of Parkinson's disease (PD), including several within the LRRK2 gene. However, little is known about the signals that underlie LRRK2-mediated neuronal loss. One clue resides in the finding that the neurodegenerative cascades emanate from signals arising from the peripheral immune system. Here, using two chimeric mouse models, we demonstrate that: 1) the replacement of mutant LRRK2 with wt form of the protein in T- and B-lymphocytes diminishes LPS-mediated inflammation and rescues the SNpc DA neuron loss in the mutant LRRK2 brain; 2) the presence of G2019S or R1441G LRRK2 mutation in …

Machines, Intimacy Topics For Two Hybrid Oxford Science Cafes, Edwin B. Smith

University of Mississippi News

Computer science, neuroscience professors to present during in-person and virtual events

Improving Capture Methods For Neonate Ungulates, Matthew T. Turnley

Theses and Dissertations

The capture of neonate ungulates has played an integral role in studies of habitat selection, phenology, survival, and other topics of ecological interest. However, neonates can be difficult for researchers to locate and capture. Neonate ungulates are born in habitats with reduced visibility, frequently spend time in a concealed, prone position, and may display cryptic coloration. In an attempt to improve researchers' likelihood of locating and capturing neonate ungulates, multiple capture methods have been developed. Much remains unknown about biases associated with capture methods and how to further improve capture methods once biases are understood. Our objectives were to determine …

Moderate-Intensity Risk Reduction Counseling And Acquisition Of Sexually Transmitted Infection, Cindy M. Farina

Dissertations

Sexually transmitted infections (STIs) are a public health problem in the United States, with adolescents and young adults to age 25 bearing a disproportionate burden of infection. Risk reduction counseling (RRC) as a strategy to decrease STI incidence has been a focus of scholars. Research examining RRC efficacy has suggested that RRC is effective for 6 to 12 months after treatment. However, study samples have varied by age, ethnicity, race, gender, and geographic location. Whether RRC is effective for more than 1 year is unknown. The purpose of this post hoc chi-square study was to examine the efficacy of moderate-intensity …

Landscape Of Molecular Crosstalk Perturbation Between Lung Cancer And Covid-19, Aditi Kuchi, Jiande Wu, Jyotsna Fuloria, Chindo Hicks

School of Medicine Faculty Publications

Background: Lung cancer patients have the worst outcomes when affected by coronavirus disease 2019 (COVID-19). The molecular mechanisms underlying the association between lung cancer and COVID-19 remain unknown. The objective of this investigation was to determine whether there is crosstalk in molecular perturbation between COVID-19 and lung cancer, and to identify a molecular signature, molecular networks and signaling pathways shared by the two diseases. Methods: We analyzed publicly available gene expression data from 52 severely affected COVID-19 human lung samples, 594 lung tumor samples and 54 normal disease-free lung samples. We performed network and pathways analysis to identify molecular networks …

Programs Committee Agenda 3/15/22, Angela Brock

Programs Committee (PC)

No abstract provided.

California Constitutional Law: Privacy, David A. Carrillo, Stephen M. Duvernay, Rodolfo E. Rivera Aquino, Brandon V. Stracener

San Diego Law Review

California voters passed Proposition 11 (the Privacy Initiative) in 1972, amending the state constitution to include a fundamental right to privacy. The ballot arguments for Proposition 11 expressed the voters’ intent to set a high bar for invaders to justify privacy invasions: requiring a compelling public need. For the first twenty years of the new constitutional privacy right’s existence, courts required invaders of individual privacy to meet the compelling public need standard to justify such invasions.

Yet the courts reversed course in 1994, abandoned the compelling public need standard, and have since applied a standard that perverts the electorate’s intent: …

Drosophila Functional Screening Of De Novo Variants In Autism Uncovers Damaging Variants And Facilitates Discovery Of Rare Neurodevelopmental Diseases, Paul C Marcogliese, Samantha L Deal, Jonathan Andrews, J Michael Harnish, V Hemanjani Bhavana, Hillary K Graves, Sharayu Jangam, Xi Luo, Ning Liu, Danqing Bei, Yu-Hsin Chao, Brooke Hull, Pei-Tseng Lee, Hongling Pan, Pradnya Bhadane, Mei-Chu Huang, Colleen M Longley, Hsiao-Tuan Chao, Hyung-Lok Chung, Nele A Haelterman, Oguz Kanca, Sathiya N Manivannan, Linda Z Rossetti, Ryan J German, Amanda Gerard, Eva Maria Christina Schwaibold, Sarah Fehr, Renzo Guerrini, Annalisa Vetro, Eleina England, Chaya N Murali, Tahsin Stefan Barakat, Marieke F Van Dooren, Martina Wilke, Marjon Van Slegtenhorst, Gaetan Lesca, Isabelle Sabatier, Nicolas Chatron, Catherine A Brownstein, Jill A Madden, Pankaj B Agrawal, Boris Keren, Thomas Courtin, Laurence Perrin, Melanie Brugger, Timo Roser, Steffen Leiz, Frederic Tran Mau-Them, Julian Delanne, Elena Sukarova-Angelovska, Slavica Trajkova, Erik Rosenhahn, Vincent Strehlow, Konrad Platzer, Roberto Keller, Lisa Pavinato, Alfredo Brusco, Jill A Rosenfeld, Ronit Marom, Michael F Wangler, Shinya Yamamoto

Duncan NRI Faculty and Staff Publications

Individuals with autism spectrum disorder (ASD) exhibit an increased burden of de novo mutations (DNMs) in a broadening range of genes. While these studies have implicated hundreds of genes in ASD pathogenesis, which DNMs cause functional consequences in vivo remains unclear. We functionally test the effects of ASD missense DNMs using Drosophila through "humanization" rescue and overexpression-based strategies. We examine 79 ASD variants in 74 genes identified in the Simons Simplex Collection and find 38% of them to cause functional alterations. Moreover, we identify GLRA2 as the cause of a spectrum of neurodevelopmental phenotypes beyond ASD in 13 previously undiagnosed …

“Goodbye, My Friencels”: An Analysis Of Incel Suicide Posts, Sarah E. Daly, Albina Laskovsov

Qualitative Criminology (QC)

While an increasing number of researchers, non-profit organizations, and law enforcement agencies have expressed growing concern about the relationship between involuntary celibates (i.e., incels) and violence, no research to date has examined the potential for suicide and self-harm among men who call themselves incels. This study examines suicide posts shared to incel sub-Reddits that were collected by u/IncelGraveyard (N=80). The posts reveal that the notes discuss six subordinate themes, including the method of their planned attempt, the ways they used the internet, the online incel community, failed alternatives and coping, the effects of their suicide on others, and the afterlife. …

The Life History Of Drosophila Sperm Involves Molecular Continuity Between Male And Female Reproductive Tracts, Erin L. Mccullough, Emma Whittington, Akanksha Singh, Scott Pitnick, Mariana F. Wolfner, Steve Dorus

Biology

Interactions between sperm and the female reproductive tract (FRT) are critical to reproductive success and yet are poorly understood. Because sperm complete their functional maturation within the FRT, the life history of sperm is likely to include a molecular “hand-off” from males to females. Although such intersexual molecular continuity is likely to be widespread among all internally fertilizing species, the identity and extent of female contributions are largely unknown. We combined semiquantitative proteomics with sex-specific isotopic labeling to catalog the posttesticular life history of the sperm proteome and determine the extent of molecular continuity between male and FRTs. We show …

Suppression Of Pi3k Signaling Is Linked To Autophagy Activation And The Spatiotemporal Induction Of The Lens Organelle Free Zone, Rifah Gheyas, Ramon Ortega-Alvarez, Daniel Chauss, Marc Kantorow, A. Menko

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

The terminal steps of lens cell differentiation require elimination of all organelles to create a central Organelle Free Zone (OFZ) that is required for lens function of focusing images on the retina. Previous studies show that the spatiotemporal elimination of these organelles during development is autophagy-dependent. We now show that the inhibition of PI3K signaling in lens organ culture results in the premature induction of autophagy within 24 h, including a significant increase in LAMP1+ lysosomes, and the removal of lens organelles from the center of the lens. Specific inhibition of just the PI3K/Akt signaling axis was directly linked to …

Repurposing Lansoprazole And Posaconazole To Treat Leishmaniasis: Integration Of In Vitro Testing, Pharmacological Corroboration, And Mechanisms Of Action, Yash Gupta, Steven Goicoechea, Jesus G. Romero, Raman Mathur, Thomas R. Caulfield, Daniel P. Becker, Ravi Durvasula, Prakasha Kempaiah

Chemistry: Faculty Publications and Other Works

Leishmaniasis remains a serious public health problem in many tropical regions of the world. Among neglected tropical diseases, the mortality rate of leishmaniasis is second only to malaria. All currently approved therapeutics have toxic side effects and face rapidly increasing resistance. To identify existing drugs with antileishmanial activity and predict the mechanism of action, we designed a drug-discovery pipeline utilizing both in-silico and in-vitro methods. First, we screened compounds from the Selleckchem Bio-Active Compound Library containing ~1622 FDA-approved drugs and narrowed these down to 96 candidates based on data mining for possible anti-parasitic properties. Next, we completed preliminary in-vitro testing …

Ucc Minutes 3/15/22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Anatomic Considerations Of Perinasal Musculature For Improved Dental Show During Smile In Facial Synkinesis, Laura T. Hetzler, Marcus Hershey, Todd Lambert, Jason Mussell, Lee Mcdaniel, Sara Macdowell

School of Medicine Faculty Publications

Introduction: There is an anatomic explanation for upper lip and midfacial tethering resulting in lack of motion in facial synkinesis. Objective: To measure the effect of perinasal chemodenervation on dental show in the synkinetic population and clarify the anatomic relationship of perinasal musculature. Methods: Literature search was performed on anatomy of the perinasal modiolus, and anatomic evaluation was performed through human anatomic specimen dissection. Photographic outcomes were observed in synkinetic patients receiving chemodenervation to smile antagonists with and without perinasal muscle injections and assessed through naive observer survey. Retrospective outcomes for all patients receiving perinasal chemodenervation was collected utilizing Facial …

Modeling Cyanobacteria Vertical Migration, Corina Christina Mae Overman, Scott A. Wells

Civil and Environmental Engineering Faculty Publications and Presentations

Cyanobacteria often cause harmful algal blooms and release toxic substances that can harm humans and animals. Accurately modeling these phytoplankton is a step towards predicting, preventing, and controlling such blooms. Certain cyanobacteria species are known to migrate vertically in the water column on a daily cycle. Capturing this behavior is one aspect of modeling their dynamics. Previous studies on modeling cyanobacterial vertical migration are reviewed and summarized. Several models of cyanobacteria vertical movement are tested using data from field studies. These models are applied using both continuum and particle-tracking frameworks. Models range in complexity from simple functions of time to …

Miami University, Oxford, Ohio, With Miami Men, Circa 1920

Documents

46-page prospectus titled "With Miami Men" published by Miami University in Oxford, Ohio, circa 1920.

Goodwyn Institute, Memphis, Announcement, 1931

Documents

Announcement for the 25th season of the Goodwyn Institute, Memphis, Tennessee, with the program of lectures for 1931-1932.

The Hybridization Of Home: Establishing Place Between The Garrison And The Wilderness In Mary Rowlandson's (1682) Captivity Narrative, Brooke M. Weltch

USF Tampa Graduate Theses and Dissertations

Scholarship surrounding captivity narratives long agrees that the psychological and philosophical beliefs of their authors lend insight into the contemporaneous hegemonic power structures through literary forms. Looking beyond these forms to the places they describe, however, illustrates the extent to which cultural perceptions infiltrate even the mere relationships that individuals have with their environment as well as the material structures surrounding them. I focus the role of place in Mary Rowlandson’s narrative, The Soveraignty and Goodness of God (1682). I argue that Rowlandson forms an attachment with the wigwam on account of her traumatic experiences while in captivity. Her displacement …