Digital Commons Network^™

237 -- Tetrahydrocannabinol Produces Locomotor Hyperactivity And Disrupts Circadian Rhythmicity In Pregnant Or Nursing Long-Evans Rats., Vincent Markowski, Joey Morgan, Anna Hendricks

GREAT Day Posters

Studies have demonstrated that exposure to cannabis during development impairs cognitive processes in humans, as well as locomotor activity and learning in animals. This extends to pregnant women and those caring for newborns. The legalization of marijuana can confer an underestimation of the effects of the more potent cannabinoids such as tetrahydrocannabinol (THC). This can lead to increased in utero exposure and postnatal exposure via breastfeeding. Newborns can also be affected if maternal care is compromised during an acute high. The current study used VitalView software and cage-top infrared activity monitors to quantify the effects of a range of THC …

238 -- Using Mathematical Modeling To Create A New Pyramidal Compost Bucket Design, Elizabeth Klosko

GREAT Day Posters

SUNY Geneseo's campus has a compost collecting program where students, faculty, and staff can empty their compostable items into bins which are emptied weekly. However, the bins release a putrid scent when opened, deterring SUNY Geneseo community members from using them. A phenomena commonly known as Pyramid Power claims that the pyramid shape, when exactly scaled to the size of the Great Pyramid of Giza, has properties that, once compostable items are put under it, can limit the growth of microorganisms and therefore reduce the foul smell. Using a 3-D printing device, we will scale and print the pyramid to …

250 -- Effects Of A Ketogenic Diet On The Stereotypy And Sociability Of Model Mice, Julie Perrone, Sean Mcbride, Aadam Mirza

GREAT Day Posters

The Ketogenic (KD) diet is a high-fat, low-carb diet that has been used as an effective treatment for disorders such as epilepsy and other brain disorders characterized by repetitive behaviors. In this experiment, we explore the effects of KD on the sociability of stereotypic mice using a 3-chambered social assay. Moreover, due to the lack of literature on estrous cycles’ interactions, we also examine the relationship, if any, between these variables and the estrous cycles of our female mice. Further research will explore the mechanism to which KD affects stereotypy and sociability as well as its relationship with the estrous …

066 -- Feeding Morphology Of Deep-Sea Demersal Fishes, Ryan Bohen, Chryssanthi Tzetzis

GREAT Day Posters

Deep-sea inhabitants survive high pressure, limited food availability, lack of sunlight, and cold temperatures. These deep-sea conditions have spurred adaptations that allow organisms to fill an array of niches. For example, distinctive feeding modes and jaw morphologies enable organisms to utilize the food resources available in their environment. Here, we investigate feeding biomechanics in deep-sea fishes across three families of fishes, the rattails (Macrouridae), snailfishes (Liparidae), and cutthroat eels (Synaphobranchidae). Each of these families exist in abundance and occupy important ecological roles in their environment. We compare jaw morphologies and mechanics between families to gain insights into feeding mode, including …

061 -- Enhancing The Classroom Environment Through The Imaginarium And Terc Internship, Becky Leathersich, Valerie Groccia, Hannah Johnston, Charis Law

GREAT Day Posters

The classroom environment is a critical component to a student’s success. We want to create an environment where students feel accommodated and comfortable to learn and grow. While we continue to navigate an ever-changing world of education, it has become apparent that the way we organize our classroom to reach students needs to evolve, as well. Throughout our time as the Imaginarium and Teacher Education Resource Center (TERC) interns, we have recognized similarities when trying to connect with members of the SUNY Geneseo Ella Cline Shear School of Education. We have spent the 2021-2022 academic school year researching and developing …

135 -- Felidae Prey Preference And Skull Morphology: How Do Sabertooth Cat Skulls Compare Against Their Extant Relatives?, Brionn Currier

GREAT Day Posters

The family Felidae (i.e., cats) is composed entirely of hypercarnivores—animals who are solely adapted for consuming prey. As a result of this, the skull morphology of felids is highly conserved across species with some deviations to accommodate the difference in relative prey size selection. Generally, felids can be broken down into small prey, large prey, and mixed prey specialists. The purpose of this research was to use geometric morphometrics to quantify the differences in skull shape between felid species based on prey size specialization and to use those findings as a baseline for comparison with the extinct felid Smilodon fatalis …

139 -- Musculature Of The Bizarre Forelimb Of The Alvarezsaurid Mononykus Olecranus (Dinosauria: Theropoda) And Its Implications For Digging, Jada Smith

GREAT Day Posters

Mononykus olecranus, from the Late Cretaceous of Mongolia, was a small, nonavian theropod dinosaur belonging to the clade Alvarezsauria. Some have hypothesized that derived members of this clade may have had an insectivorous diet, and might be specialized as ant or termite eaters, due to the unusual morphology of the forelimb. The forelimbs of Mononykus are distinctly stunted in size with only one digit and claw on each hand. In order to investigate the hypothesis that these forelimbs were used in digging, we completed the first muscular reconstruction of the forelimbs of Mononykus. Previous muscular reconstructions of the early theropod …

A Review Of Avian-Inspired Morphing For Uav Flight Control, Christina Harvey, Lawren L. Gamble, Christian R. Bolander, Douglas F. Hunsaker, James J. Joo, Daniel J. Inman

Mechanical and Aerospace Engineering Faculty Publications

The impressive maneuverability demonstrated by birds has so far eluded comparably sized uncrewed aerial vehicles (UAVs). Modern studies have shown that birds’ ability to change the shape of their wings and tail in flight, known as morphing, allows birds to actively control their longitudinal and lateral flight characteristics. These advances in our understanding of avian flight paired with advances in UAV manufacturing capabilities and applications has, in part, led to a growing field of researchers studying and developing avian-inspired morphing aircraft. Because avian-inspired morphing bridges at least two distinct fields (biology and engineering), it becomes challenging to compare and contrast …

Black Carbon And Meteorological Parameters At Two Locations In Northern Mississippi, Ashton Swader

Honors Theses

Black Carbon, which is a component of fine particulate matter, is a known pollutant that has been linked to the development of several diseases including cardiovascular disease. This pollutant can be measured by taking samples of air within a certain region and analyzing them using a transmissometer. It is known that black carbon concentrations tend to be higher in urban areas when compared to rural areas within a region. Black carbon concentrations can also vary depending on certain meteorological parameters such as temperature and humidity. There were no current studies that analyze the air quality in northern Mississippi due to …

Cushion Sea Stars (Oreaster Reticulatus) Have The Ability To Respond To Disturbance, Peyton Kopel, Thomas Ellis

Celebrating Scholarship and Creativity Day (2018-)

We were interested in the distance of movement among cushion sea stars (Oreaster reticulatus) located in Graham’s Harbor, San Salvador, Bahamas. We hypothesized that there is a difference in distance moved when the starfish are under disturbed conditions as compared to undisturbed conditions. Based on our hypothesis, we predicted that the starfish move further when disturbed in comparison to when they have not been disturbed. The data was collected through six trials, over the course of three days (9-11 March, 2022). For the disturbed environment, we collected the starfish and placed them in a central location. From there, we measured …

Structural Preference Of Banded (Ophiolepis Apressa) And Reticulated (Ophionereis Reticulata) Brittle Stars, Sophie Stoffers, Jillian Neudahl

Celebrating Scholarship and Creativity Day (2018-)

Research was conducted on the habitat preference of brittle stars (Ophiodermatidae), located on the coast of the island San Salvador in the Bahamas. These marine organisms feed during the night and hide within dark areas of the ocean such as rocks and conch shells during the day. We hypothesized that brittle stars had no preference for the structure they chose to hide in during the daytime. Based on this hypothesis, we predicted that brittle stars would utilize all structural areas equally. Two species of brittle stars (Ophionereis reticulata and Ophiolepis apressa) were our study animals. Six reticulated brittle stars and …

Alpha Synuclein: A Therapeutic Target And Biomarker For Parkinson’S Disease, Max Chase

USF Tampa Graduate Theses and Dissertations

Parkinson’s Disease is the second most common neurodegenerative disease after Alzheimer’s Disease, and the most common motor disorder. In fact, nearly a third of those with AD have PD. A major hallmark of PD is the appearance of Lewy Bodies, proteinaceous cytoplasm inclusions, that build up and spread throughout the CNS in a prion like fashion. The major component of these Lewy Bodies is a protein called alpha-synuclein. Alpha-syn is a 14kDa protein made of 140 amino acids and found in the presynaptic ends of CNS neurons, acting as a chaperone and regulator. The protein is also found in the …

Retrospective Genomics Highlights Changes In Genetic Composition Of Tiger Sharks (Galeocerdo Cuvier) And Potential Loss Of A South-Eastern Australia Population, Alice Manuzzi, Belen Jiménez-Mena, Romina Henriques, Bonnie J Holmes, Julian Pepperell, Janette Edson, Mike B Bennett, Charlie Huveneers, Jennifer R Ovenden, Einar E Nielsen

Staff and Researcher Publications

Over the last century, many shark populations have declined, primarily due to overexploitation in commercial, artisanal and recreational fisheries. In addition, in some locations the use of shark control programs also has had an impact on shark numbers. Still, there is a general perception that populations of large ocean predators cover wide areas and therefore their diversity is less susceptible to local anthropogenic disturbance. Here we report on temporal genomic analyses of tiger shark (Galeocerdo cuvier) DNA samples that were collected from eastern Australia over the past century. Using Single Nucleotide Polymorphism (SNP) loci, we documented a significant change in …

A Combined Conduit-Bioactive Hydrogel Approach For Regeneration Of Transected Sciatic Nerves, Cheuk Sun Edwin Lai, Viridiana Leyva-Aranda, Victoria H Kong, Tania L Lopez-Silva, Adam C Farsheed, Carlo D Cristobal, Joseph W R Swain, Hyun Kyoung Lee, Jeffrey D Hartgerink

Duncan NRI Faculty and Staff Publications

Transected peripheral nerve injury (PNI) affects the quality of life of patients, which leads to socioeconomic burden. Despite the existence of autografts and commercially available nerve guidance conduits (NGCs), the complexity of peripheral nerve regeneration requires further research in bioengineered NGCs to improve surgical outcomes. In this work, we introduce multidomain peptide (MDP) hydrogels, as intraluminal fillers, into electrospun poly(ε-caprolactone) (PCL) conduits to bridge 10 mm rat sciatic nerve defects. The efficacy of treatment groups was evaluated by electromyography and gait analysis to determine their electrical and motor recovery. We then studied the samples' histomorphometry with immunofluorescence staining and automatic …

Kenyon Collegian - April 21, 2022

The Kenyon Collegian

No abstract provided.

Using Mitogenomes To Explore The Social And Ecological Contexts Of Crocodile Mummification In Ancient Egypt, Salima Ikram, Evon R. Hekkala, Roger Colten, Seth W. Cunningham

Faculty Journal Articles

We used isotopic and genomic data to explore the ecological and social context of cultural practices associated with the mummification of crocodiles in ancient Egypt. Ancient DNA was recovered from four mummified crocodile hatchlings held in the collections of the Peabody Museum of Natural History, Yale University. Previous genetic analyses of crocodile mummies have indicated that most mummies represent the newly resurrected taxon, Crocodylus suchus Geoffroy Saint-Hilaire, 1807. However, mitogenomic data for the Yale Peabody Museum mummies indicates that these specimens represent the first genomically authenticated representatives of the Nile crocodile (Crocodylus niloticus Laurenti, 1768) in museum collections. We explore …

Only Libertarianism Can Provide A Robust Justification For Open Borders, Christopher Freiman, Javier S. Hidalgo

Jepson School of Leadership Studies articles, book chapters and other publications

This paper argues that libertarianism—and only libertarianism—can vindicate immigration's status as a human right whose protection is morally required in nearly all circumstances. Competing political theories such as liberal egalitarianism fail to rule out significant immigration restrictions in a range of realistic conditions. We begin by outlining the core tenets of libertarianism and their implications for immigration policy. Next, we explain why arguments that appeal to alternative principles are unable to provide robust justification for open borders. We conclude by considering whether our argument vindicates libertarianism or undermines open borders.

The Gibbs House: Visual Storytelling Through Brand Identity And Placemaking, Elizabeth Tran

Honors Theses

Managed by Western Michigan University’s (WMU) Office for Sustainability, the Gibbs House has a rich history of existing as the functioning university urban farm since the late 60s. Throughout the years, the location has transformed into a learning laboratory as well as a permaculture research and demonstration site for WMU students and the Kalamazoo community. As individuals scramble to come up with solutions to combat climate change, the two-acre plot becomes a vital resource where students are able to participate in sustainable practices that are both hands-on and outdoors. It pushes forward transformative ideas like composting, food forestry, and permaculture …

Bis-Cinnamamide Derivatives As Ape/Ref-1 Inhibitors For The Treatment Of Human Melanoma, Razan Alhazmi, Shirley Tong, Shaban Darwish, Elina Khanjani, Bharti Khungar, Swati Chawla, Zhonghui Zheng, Richard Chamberlain, Keykavous Parang, Sun Yang

Pharmacy Faculty Articles and Research

Human malignant melanoma exhibits imbalances in redox status, leading to activation of many redox-sensitive signaling pathways. APE/Ref-1 is a multifunctional protein that serves as a redox chaperone that regulates many nuclear transcription factors and is an important mechanism in cancer cell survival of oxidative stress. Previous studies showed that APE/Ref-1 is a potential druggable target for melanoma therapy. In this study, we synthesized a novel APE/Ref-1 inhibitor, bis-cinnamoyl-1,12-dodecamethylenediamine (2). In a xenograft mouse model, compound 2 treatment (5 mg/kg) significantly inhibited tumor growth compared to the control group, with no significant systemic toxicity observed. We further synthesized compound …

A Nation Joins In Tears: Implications Of The Domestic Deployment Of Federal Troops In Portland, Oregon, Marissa Cohen, Jacqueline Stevens

North Carolina Civil Rights Law Review

No abstract provided.

Blue V. Durham Public School District And The Campaign For School Equalization In North Carolina, Donovan J. Stone

North Carolina Civil Rights Law Review

No abstract provided.

Abscond Runner, Jabari Belgrave, Jeremiah Coleman, Sa Liu

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

Abscond Runner is a game we've made based on the movie and book series "The Maze Runner". This is a first-person novel experience where the player must go through the maze by maneuvering through obstacles and destroying the enemies to reach the end. (Class Project)

Medical Testing On Animals, Celebrity Wright, Nyicia Morgan, Akeisha Belgrave

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

We will be investigating and researching undergraduate students’ opinions on animal use in medical testing. (Class Project)

A Study Into The Ownership And Care Of Animals Among The Hu Community, Amir Khan, Akeisha Belgrave

Harrisburg University Research Symposium: Highlighting Research, Innovation, & Creativity

My project involves understanding the animal care routines of persons in the HU Community. (Class Project)

Exploring Retinal Projection To The Medial Amygdala: Laterality, Sex, And Cell Types, Shikhar Gupta '22, Kavin Suhirtharen '22

IMSAloquium Student Investigation Showcase

In the mouse brain, there are 59 retinorecipient regions, including the medial amygdala (MeA). The MeA is a sensory integrating region where social information is processed, especially those related to sexual selection, aggression, and pup retrieval. The neurons that link visual input to the brain are known as retinal ganglion cells (RGCs). There are ~47 mouse RGC subtypes, each with their own light stimulus sensitivities and activity patterns. As the MeA is notorious as the sexually dimorphic social behavioral hub, it is worthwhile beginning to explore sex differences or laterality differences in this retinorecipient area. Using anterograde, intravitreal injections in …

Industrial Cooperation, Earl Clement Davis

Manuscripts

A lengthy analysis on how to have more productive and humane systems of production, by aligning the three necessary elements of production (capital, management, and labor) in a more "organic" way. Interesting examples include Edme-Jean Leclaire (1801-1872) and N.O. Wilson (1844-1922).

The bottom of each item page also features the primary document as an embedded pdf for browsing.

Transcription by Davis Baird. Item description based off writing and context provided by Davis Baird.

Losing God, Jordan Pugh

Calliope

No abstract provided.

Macho, David Hayhurst

Calliope

No abstract provided.

Full Issue

Calliope

No abstract provided.

Intra-Articular Buprenorphine In Horses, Gabriel Castro-Cuellar Dr

LSU Master's Theses

Opioid drugs have the potential of provide local analgesia in inflamed joints. To date, morphine is the only opioid that has been tested for intra-articular (IA) administration in horses. Having an alternative drug, other than morphine, could widen the therapeutic options, particularly in cases of drug shortages or inaccessibility to specific drugs. The work presented in this dissertation reports the cytotoxic effects of buprenorphine on cultured equine chondrocytes, and the pharmacokinetic, pharmacodynamic and analgesic effects, of IA administered buprenorphine in horses with experimentally induced synovitis.

To evaluate the potential cytotoxic effects on equine cartilage, chondrocytes were obtained from normal equine …