Digital Commons Network^™

Imaging Breast Adipose And Fibroglandular Tissue Molecular Signatures By Using Hybrid Mri-Guided Near-Infrared Spectral Tomography, Ben Brooksby, Brian W. Pogue, Shudong Jiang, Hamid Dehghani, Subhadra Srinivasan, Christine Kogel, Tor D. Tosteson, John Weaver, Steven P. Poplack, Keith D. Paulsen

Dartmouth Scholarship

Magnetic resonance (MR)-guided near-infrared spectral tomography was developed and used to image adipose and fibroglandular breast tissue of 11 normal female subjects, recruited under an institutional review board-approved protocol. Images of hemoglobin, oxygen saturation, water fraction, and subcellular scattering were reconstructed and show that fibroglandular fractions of both blood and water are higher than in adipose tissue. Variation in adipose and fibroglandular tissue composition between individuals was not significantly different across the scattered and dense breast categories. Combined MR and near-infrared tomography provides fundamental molecular information about these tissue types with resolution governed by MR T1 images.

Medial Prefrontal Dissociations During Processing Of Trait Diagnostic And Nondiagnostic Person Information, Jason P. Mitchell, Jasmin Cloutier, Mahzarin R. Banaji, C Neil Macrae

Dartmouth Scholarship

Previous research has suggested that perceivers spontaneously extract trait-specific information from the behaviour of others. However, little is known about whether perceivers spontaneously engage in the same depth of social-cognitive processing for all person information or reserve such processing specifically for information that conveys diagnostic clues about another person's dispositions. Moreover, a question remains as to whether the processing of such nondiagnostic information can be affected by perceivers’ explicit goal to consider another's dispositions or not. To examine processing of diagnostic and nondiagnostic social information as a function of perceivers’ explicit social-cognitive goals, participants underwent functional magnetic resonance imaging (fMRI) …

Where To Play?: How Student-Athletes Perceive The College Choice Process, Arrianna Smith

LSU New Orleans Theses and Dissertations

The study explored the perceptions of thirteen, female student-athletes who chose to participate in intercollegiate athletics, specifically basketball. Each of the participants was enrolled at a Division I institution in the same athletic conference. Both institutions are nationally ranked institutions in their primary (revenue generating) sport (NCAA, 2004). All of the participants were offered full athletic scholarships to other institutions, yet they made their college choice decision based on multiple factors. The data revealed that although student-athletes undergo a similar process as non-athletes, their experience in many ways was different due to the additional factors they have to consider. As …

Incidence Of Galactorrhea In Young Women Using Depot-Medroxyprogesterone Acetate, Hatim A. Omar, Rana M. Zakharia, Shibani Kanungo, Marlene B. Huff, Kimberly K. Mcclanahan

Pediatrics Faculty Publications

Galactorrhea is rarely mentioned as a possible side effect of the use of Depot-Medroxyprogesterone Acetate (DMPA). Over the last few years, we have noticed an increased number of patients complaining of galactorrhea. A review of clinical data showed that between 1999 and 2005, 360 adolescents in our clinic used DMPA for at least 6 months. After medical follow-up, 13 (3.6%) of these patients were found to have developed galactorrhea. The mean age of the patients was 19.4 years with a range from 13-24. Prolactin levels in these patients were normal, and in all subjects, the galactorrhea resolved spontaneously within the …

Level I Fieldwork Today: A Study Of Contexts And Perceptions., Caryn Johnson, Kristie P. Koenig, Catherine Verrier Piersol, Susan E. Santalucia, Wendy Wachter-Schutz

Department of Occupational Therapy Faculty Papers

The last comprehensive examination of the Level I fieldwork experience was performed 15 years ago (Shalik, 1990) and addressed the different types of settings in which fieldwork occurred; amounts and types of supervision; structure and scheduling of the Level I experiences; and the effects of supervising Level I students on productivity. Although every occupational therapy and occupational therapy assistant student encounters a number of Level I fieldwork opportunities, little is available describing the process and contexts of the Level I fieldwork experience today. This study, which examines 1,002 student reports on Level I fieldwork experiences, finds that Level I fieldwork …

Accuracy And Self Correction Of Information Received From An Internet Breast Cancer List: Content Analysis, Adol Esquivel, Funda Meric-Bernstam, Elmer V Bernstam

Faculty, Staff and Student Publications

OBJECTIVES: To determine the prevalence of false or misleading statements in messages posted by internet cancer support groups and whether these statements were identified as false or misleading and corrected by other participants in subsequent postings. DESIGN: Analysis of content of postings. SETTING: Internet cancer support group Breast Cancer Mailing List. MAIN OUTCOME MEASURES: Number of false or misleading statements posted from 1 January to 23 April 2005 and whether these were identified and corrected by participants in subsequent postings. RESULTS: 10 of 4600 postings (0.22%) were found to be false or misleading. Of these, seven were identified as false …

A Role For Cetp Taqib Polymorphism In Determining Susceptibility To Atrial Fibrillation: A Nested Case Control Study, Folkert W. Asselbergs, Jason H. Moore, Maarten P. Van Den Berg, Eric B. Rimm

Dartmouth Scholarship

Studies investigating the genetic and environmental characteristics of atrial fibrillation (AF) may provide new insights in the complex development of AF. We aimed to investigate the association between several environmental factors and loci of candidate genes, which might be related to the presence of AF. A nested case-control study within the PREVEND cohort was conducted. Standard 12 lead electrocardiograms were recorded and AF was defined according to Minnesota codes. For every case, an age and gender matched control was selected from the same population (n = 194). In addition to logistic regression analyses, the multifactor-dimensionality reduction (MDR) method and interaction …

Voices Raised, Issue 12, University Of Dayton. Women's Center

Women’s Center Newsletter

Included in this issue: Enhancing the Climate for Women; Gay? Fine by me; Wisdom from some of UD’s busiest women; Don’t forget…Mother’s Day; WGS Moves Forward; Mentoring Program: Continuing to Grow; Connecting to UD; Committee strives for feminist voices to be heard; Women’s roles may not be as expected; Fighting oppression, one pornographic image at a time; Music can be a source of empowerment or degradation or women.

Successful Treatment Of Depot Medroxyprogesterone Acetate-Related Vaginal Bleeding Improves Continuation Rates In Adolescents, Kristin M. Rager, Amy Fowler, Hatim A. Omar

Pediatrics Faculty Publications

High discontinuation rates for depot medroxyprogesterone acetate (DMPA) in adolescents may contribute to the number of unintended pregnancies. Many cite vaginal bleeding as a reason for discontinuing DMPA use. In this study, we attempted to determine if treating DMPA-associated vaginal bleeding with monophasic oral contraceptive pills (OCP) raised continuation rates. A total of 131 patients who reported vaginal bleeding while on DMPA were included in this study and 83 were treated with monophasic OCP. Of those who received OCP, 38.7% reported that vaginal bleeding stopped completely, 51.8% reported that vaginal bleeding stopped temporarily, and 6.0% reported no change. Overall, 94% …

Clinical Holistic Medicine: Holistic Sexology And Acupressure Through The Vagina (Hippocratic Pelvic Massage), Søren Ventegodt, Birgitte Clausen, Hatim A. Omar, Joav Merrick

Pediatrics Faculty Publications

Many gynecological and sexological problems (like urine incontinence, chronic pelvic pains, vulvodynia, and lack of lust, excitement, and orgasm) are resistant to standard medical treatment. In our work at the Research Clinic for Holistic Medicine in Copenhagen, we have found that vaginal acupressure, or Hippocratic pelvic massage, can help some of these problems. Technically, it is a very simple procedure as it corresponds to the explorative phase of the standard pelvic examination, supplemented with the patient's report on the feelings it provokes and the processing and integration of these feelings. Sometimes it can be very difficult to control the emotions …

Hepatic And Renal Cytochrome P450 Gene Regulation During Citrobacter Rodentium Infection In Wild-Type And Toll-Like Receptor 4 Mutant Mice, Terrilyn A Richardson, Melanie Sherman, Leposava Antonovic, Sean S Kardar, Henry W Strobel, Daniel Kalman, Edward T Morgan

Faculty, Staff and Student Publications

Citrobacter rodentium is the rodent equivalent of human enteropathogenic Escherichia coli infection. This study investigated regulation of hepatic and renal cytochrome P450 (P450) mRNAs, hepatic P450 proteins, cytokines, and acute phase proteins during C. rodentium infection. Female C3H/HeOuJ (HeOu) and C3H/HeJ (HeJ) mice [which lack functional toll-like receptor 4 (TLR4)] were infected with C. rodentium by oral gavage and sacrificed 6 days later. Hepatic CYP4A10 and 4A14 mRNAs were decreased in HeOu mice (

Voices Raised, Issue 11, University Of Dayton. Women's Center

Women’s Center Newsletter

Included in this issue: Women’s History Month; HERS develops future women leaders; Women’s Leadership Conference promises real stories from real women; New Opportunities in Women’s Studies; UD’s Woman of Influence; The Art of Irish Dance; Body Monologues calls for thoughts about your body; UD Monologues is a diverse show everyone can relate to; Keep your mind and heart open to new possibilities.

Type 3 Deiodinase Is Critical For The Maturation And Function Of The Thyroid Axis, Arturo Hernandez, M. Elena Martinez, Steven Flering, Valerie Anne Galton, Donald St. German

Dartmouth Scholarship

Developmental exposure to appropriate levels of thyroid hormones (THs) in a timely manner is critical to normal development in vertebrates. Among the factors potentially affecting perinatal exposure of tissues to THs is type 3 deiodinase (D3). This enzyme degrades THs and is highly expressed in the pregnant uterus, placenta, and fetal and neonatal tissues. To determine the physiological role of D3, we have generated a mouse D3 knockout model (D3KO) by a targeted inactivating mutation of the Dio3 gene in mouse ES cells. Early in life, D3KO mice exhibit delayed 3,5,3′-triiodothyronine (T3) clearance, a markedly elevated serum T3 level, and …

Androgen Excess Disorders In Women: The Severe Insulin-Resistant Hyperandrogenic Syndrome, Hair-An, Kristin M. Rager, Hatim A. Omar

Pediatrics Faculty Publications

HAIR-AN syndrome (hyperandrogenism, insulin resistance, acanthosis nigricans) is a subset of the polycystic ovary syndrome, where the patients demonstrate severe insulin resistance. It is theorized that both genetic and environmental factors, such as obesity, give rise to the development of HAIR-AN. Diagnosis is primarily clinical, with laboratory values lending further support. Treatment is aimed at decreasing insulin resistance, regulating ovulation, and decreasing acne, acanthosis nigricans, and hirsutism.

Changes In Immunological And Hematological Parameters Of Female Residents Exposed To Volatile Organic Compounds In The City Of Kaohsiung, Taiwan, Hueiwang Anna Jeng, I-Long Lee, Yang-Yen Gau, Ching-Tzu Yang, Chitsan Lin, Yu-Jue Hong

Community & Environmental Health Faculty Publications

The objective of this study was to assess the effects, if any, of volatile organic compounds (VOCs) in the ambient air of Kaohsiuug, Taiwan, on certain hematological and immunological parameters of 153 female study participants. The major source of VOCs was vehicle emissions. The participants were selected from three areas, each area at a different distance from a freeway. Results indicated that total concentrations of VOCs and a subgroup of 25 VOCs (VOC₂₅.) ranged from 250 to 335 ppb and 89 to 113 ppb, respectively. The distribution of VOC concentrations did not correlate with distance from the freeway. …

Loyalt's Reward - A Felony Conviction: Recent Prosecutions Of High-Status Female Offenders, Michelle S. Jacobs

Fordham Urban Law Journal

This Article analyzes white-collar female crime and compares several high profile cases to those of regular female offenders. It uses government statistical data on female crime to paint a portrait of the female offender. It then compares the prosecution of "street-level" and white-collar female offenders. The Article discusses the prosecutions of Martha Stewart, Betty, Vinson, and Lea Fastow. The Article argues that these women often share a similar trait of committing the crime out of loyalty to a man engaged in wrong-doing.

10x The Talent = 1/3 Of The Credit: How Female Musicians Are Treated Differently In Music, Meggan Jordan

Electronic Theses and Dissertations

This is an exploratory, qualitative study of female musicians and their experiences with discrimination in the music industry. Using semi-structured interviews, I analyze the experiences of nine women, ages 21 to 56, who are working as professional musicians, or who have worked professionally in the past. I ask them how they are treated differently based on their gender. Three forms of subtle discrimination are inferred from their narrative histories. First, female musicians are mistaken for non-musicians. They are encapsulated into inferior roles, like "the gimmick," "good for a girl," and "invisible accessory." Second, band mates and band managers control women's …

Evaluation Of A Cognitive-Behavioral Group Therapy Program For The Treatment Of Posttraumatic Stress Disorder In Female Juvenile Delinquents In Residential Placements, Janet Heesen Knapp

PCOM Psychology Dissertations

Female juvenile delinquents have a high incidence of posttraumatic stress disorder (PTSD). Residential treatment programs for female juvenile offenders typically lack gender-specific programming and empirically supported treatment protocols. This study attempted to examine the effectiveness of the Alternative Rehabilitation Communities, Inc., Group Therapy Program for Female Juvenile Delinquents with Posttraumatic Stress Disorder (Alternative Rehabilitation Community, 2004). This manual-based treatment program was conducted in 5 residential treatment agencies in Pennsylvania. Two comparable agencies served as comparison sites. Data was obtained from a larger study performed by the University of Pittsburgh Office of Child Development Division of Planning and Evaluation, which had …

Painful Discourses: Borders, Regions, And Representations Of Female Circumcision From Africa To America, Tameka Latrece Cage

LSU Doctoral Dissertations

This project considers issues of representation and how literature, personal testimony, popular culture, and African film script a narrative of change and/or participate in change in the female circumcision debate. Texts that currently shape the female circumcision debate are increasingly focused on viable methods of social change and couch issues of change in dynamics of discourse and representation, including Obioma Nnaemeka’s Female Circumcision and the Politics of Knowledge: African Women in Imperialist Discourses, Rogaia Mustafa Abusharaf’s Female Circumcision: Multicultural Perspectives, and Oyèrónké Oyewùmi’s African Women and Feminism: Reflecting on the Politics of Sisterhood, all of which I cite in the …

Impact Of A Stage-Matched Weight Loss Intervention On Stage Of Change Progression In Predominantly African-American Female Primary Care Patients, Jamie Sue Bodenlos

LSU Doctoral Dissertations

Obesity is associated with several chronic medical conditions. Certain individuals are at higher risk for obesity including low-income African American females. Despite the many benefits to weight loss, many individuals do not seek treatment. Individuals are likely to attend primary care appointments where obesity can be targeted. Although stage matched interventions based on the Transtheoretical Model (TM) have been used successfully to aid in health behavior change, few studies have examined the use of stage matched weight loss interventions in African American females. There is also a paucity of research examining the effects of stage matched weight loss interventions on …

Binding Femininity: An Examination Of The Effects On Tightlacing On The Female Pelvis, Katherine Marie Klingerman

LSU Master's Theses

The corset in eighteenth and nineteenth century Europe was not merely an article of clothing. The corset was a complex and often contradictory social and cultural symbol. It symbolized both the sensual female body and the chaste virgin; the female control over male desires, and the male’s control over the female body. The ubiquity of the corset in the eighteenth and nineteenth century Europe is an important commentary on historical European society. Reports of women (and men) who have died as a result of the tightness of their corsets abound in the literature. Case studies from medical professionals provide information …

Female Athletic Trainers In Professional Male Sports, Erica Chung

UNLV Retrospective Theses & Dissertations

This study measured the opinions of head and assistant athletic trainers employed by the National Football League, National Basketball Association, National Hockey League, Major League Soccer, and Major League Baseball, which also included the affiliated minor league and independent professional teams in the spring of 2006 regarding potential barriers female athletic trainers face in order to work with professional male sports teams. A survey was distributed to measure the opinions of 373 full-time athletic trainers with a return rate of 30.6%. The majority of those that took the survey agreed that female athletic trainers were competent and skilled but the …

Classification And Risk Stratification Of Invasive Breast Carcinomas Using A Real-Time Quantitative Rt-Pcr Assay., Laurent Perreard, Cheng Fan, John F Quackenbush, Michael Mullins, Nicholas P Gauthier, Edward Nelson, Mary Mone, Heidi Hansen, Saundra S Buys, Karen Rasmussen, Alejandra Ruiz Orrico, Donna Dreher, Rhonda Walters, Joel Parker, Zhiyuan Hu, Xiaping He, Juan P Palazzo, Olufunmilayo I Olopade, Aniko Szabo, Charles M Perou, Philip S Bernard

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

INTRODUCTION: Predicting the clinical course of breast cancer is often difficult because it is a diverse disease comprised of many biological subtypes. Gene expression profiling by microarray analysis has identified breast cancer signatures that are important for prognosis and treatment. In the current article, we use microarray analysis and a real-time quantitative reverse-transcription (qRT)-PCR assay to risk-stratify breast cancers based on biological 'intrinsic' subtypes and proliferation. METHODS: Gene sets were selected from microarray data to assess proliferation and to classify breast cancers into four different molecular subtypes, designated Luminal, Normal-like, HER2+/ER-, and Basal-like. One-hundred and twenty-three breast samples (117 invasive …

Adolescent Female Embodiment As A Transformational Experience In The Lives Of Women: An Empirical Existential-Phenomenological Investigation, Allyson Havill

Electronic Theses and Dissertations

Adolescence can be a time of psychological vulnerability in the life cycle of a woman as she experiences multiple developmental changes. As articulated in the literature related to adolescent female development, a changing body may be at the heart of what can make this a time of profound transition for the adolescent girl as she attempts to negotiate alterations in her identity and self-concept, and consequently her social roles.

The purpose of this investigation of adolescent female embodiment was to understand the experience of adolescent girls as it relates to their changing bodies, and to explore the question of whether …

Female Gender Themes In Women's Magazines: A Content Analysis Testing And Extending Themes Uncovered By Erving Goffman, Sarah Elizabeth Morton

UNLV Retrospective Theses & Dissertations

This study is based on the ideas and studies of Erving Goffman (1922-1982), an influential sociologist and communications scholar (Manning, 1992). Most prior scholars, such as McLaughlin (1999) and Reichert (2003), have chosen to simply repeat and reaffirm Goffman's themes, while largely ignoring that both times and society have changed. Thus, this study proposes not only to repeat Goffman's methods, but also to extend and retest his findings in the modern day. A quantitative content analysis will be employed, using the following women's magazines: Cosmopolitan, In Style, Allure, Glamour, and Marie Claire. The replication of this study is imperative in …

Context In Leadership: A Comparative Case Analysis Of Female Public And Private Sector Leaders, Angela Koclanes Hernquist

UNLV Retrospective Theses & Dissertations

Public higher education institutions today are fiercely competitive social, economic, and technologic powerhouses with complex missions, structures, and issues. They help fuel business and economic development through their direct impact on growth and spending and through the creation of new jobs and businesses, and have become critical sources of scientific talent, research data, and technological innovations for both the public and the private sector; In comparison, private sector enterprises today function in an environment where knowledge is economic capital and success is driven by highly skilled professional employees working in innovative organizational units to find, use, create, and transform knowledge …

Antisperm Immunity For Contraception, R. K. Naz

Faculty & Staff Scholarship

No abstract provided.

Analysis Of Epstein-Barr Virus Reservoirs In Paired Blood And Breast Cancer Primary Biopsy Specimens By Real Time Pcr., R Serene Perkins, Katherine Sahm, Cindy Marando, Diana Dickson-Witmer, Gregory R Pahnke, Mark Mitchell, Nicholas J Petrelli, Irving M Berkowitz, Patricia Soteropoulos, Virginie M Aris, Stephen P Dunn, Leslie J Krueger

Department of Surgery Faculty Papers

INTRODUCTION: Epstein-Barr virus (EBV) is present in over 90% of the world's population. This infection is considered benign, even though in limited cases EBV is associated with infectious and neoplastic conditions. Over the past decade, the EBV association with breast cancer has been constantly debated. Adding to this clinical and biological uncertainty, different techniques gave contradictory results for the presence of EBV in breast carcinoma specimens. In this study, minor groove binding (MGB)-TaqMan real time PCR was used to detect the presence of EBV DNA in both peripheral blood and tumor samples of selected patients. METHODS: Peripheral blood and breast …

Atypical Features In Pleomorphic Adenoma--A Clinicopathologic Study And Implications For Management., M. Ethunandan, R. Witton, G. Hoffman, A. Spedding, P. A. Brennan

Peninsula Dental School

Pleomorphic adenoma is the most common salivary gland neoplasm and infrequently undergoes malignant transformation. Carcinoma ex pleomorphic adenoma is typically an infiltrative neoplasm with features of cellular pleomorphism, high mitotic activity, peri-neural and vascular invasion. More recently, sub-groups of pleomorphic adenoma have been described exhibiting vascular invasion and features of malignancy without evidence of extra-capsular extension. There is little information in the literature regarding how these different histological variants influence clinical presentation and outcome following primary treatment. Following a review of 100 consecutive pleomorphic adenomas removed from the major salivary glands, 4 cases with atypical histological features were found. Three …

Ocular Morbidity Among Children Studying In Private Schools Of Kathmandu Valley: A Prospective Cross Sectional Study., Rk Shrestha, Mr Joshi, R Ghising, P Pradhan, S Shakya, A Rizyal

School of Health Professions

A prospective cross sectional study of students of two private schools was done and students were screened in detail. A total of 1816 students aged 5 to 16 years were evaluated, out of which 52.8% were males and 47.2 % were females. Among the total, 65.8% had no ocular abnormalities and 34.2% had some form of ocular disorders. Refractive error was the commonest problem seen accounting for 21.9% out of total, followed by infective disorders, which accounted for 7.2%, 3.5% of them were noted to have Orthoptic problem including various types of strabismus, 2.2% were color blind, 2.6% were found …