Digital Commons Network^™

Estrogen Hormone Is An Essential Sex Factor Inhibiting Inflammation And Immune Response In Covid-19, Fuhai Li, Adrianus C M Boon, Andrew P Michelson, Randi E Foraker, Ming Zhan, Philip R O Payne

Open Access Publications

Although vaccines have been evaluated and approved for SARS-CoV-2 infection prevention, there remains a lack of effective treatments to reduce the mortality of COVID-19 patients already infected with SARS-CoV-2. The global data on COVID-19 showed that men have a higher mortality rate than women. We further observed that the proportion of mortality of females increases starting from around the age of 55 significantly. Thus, sex is an essential factor associated with COVID-19 mortality, and sex related genetic factors could be interesting mechanisms and targets for COVID-19 treatment. However, the associated sex factors and signaling pathways remain unclear. Here, we propose …

2022-06-07_Michiganoverview_Covidlongtermcare, Michigan Department Of Health & Human Services

Michigan COVID-19 Long Term Care Data

The COVID Long Term Care Facilities page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/data-about-places/long-term-care-data.

This report is created by the Michigan Department of Health & Human Services from data self-reported by long-term care facilities into EMResource. Data for all reporting facilities is posted weekly each Monday.

The information below represents COVID-19 data reported directly to MDHHS by licensed and operating Skilled Nursing, Home for the Aged and Adult Foster Care facilities (licensed to serve 13 or more individuals) in Michigan from January 1, 2020. All long-term care facilities additionally have an obligation to report COVID-positive residents and/or staff …

Cafo’S Are A Public Health Crisis:The Creation Of Covid-19, Helena Masiello

University of Miami Law Review

Concentrated Animal Feeding Operations (“CAFO’s”) are largely unregulated by State or Federal Laws in the United States. As a result of this lack of oversight, they are a breeding ground for deadly infectious diseases. The COVID-19 epidemic has demonstrated the threat that diseases pose to the United State like H1N1, SARS, and Ebola.
The USDA needs to regulate CAFOs under the mandate given to them by congress in the AHPA to ensure that they are not the epicenter of the next wave of deadly infectious diseases. Scientists have been warning about the disease potential of CAFOs for the last decade, …

Clinical Trial Innovations In A Post-Covid World, Francisco A. Ponce, Ludy Chen Shih, Michael Staudt

Conference Presentation Abstracts

No abstract provided.

Effect Of Awake Prone Positioning On Endotracheal Intubation In Patients With Covid-19 And Acute Respiratory Failure: A Randomized Clinical Trial, Waleed Alhazzani, Ken Kuljit S Parhar, Jason Weatherald, Zainab Al Duhailib, Mohammed Alshahrani, Abdulrahman Al-Fares, Sarah Buabbas, Sujith V Cherian, Laveena Munshi, Eddy Fan, Fahad Al-Hameed, Jamal Chalabi, Amera A Rahmatullah, Erick Duan, Jennifer L Y Tsang, Kimberley Lewis, François Lauzier, John Centofanti, Bram Rochwerg, Sarah Culgin, Katlynne Nelson, Sheryl Ann Abdukahil, Kirsten M Fiest, Henry T Stelfox, Haytham Tlayjeh, Maureen O Meade, Dan Perri, Kevin Solverson, Daniel J Niven, Rachel Lim, Morten Hylander Møller, Emilie Belley-Cote, Lehana Thabane, Hani Tamim, Deborah J Cook, Yaseen M Arabi, Covi-Prone Trial Investigators And The Saudi Critical Care Trials Group

Faculty, Staff and Student Publications

Importance: The efficacy and safety of prone positioning is unclear in nonintubated patients with acute hypoxemia and COVID-19.

Objective: To evaluate the efficacy and adverse events of prone positioning in nonintubated adult patients with acute hypoxemia and COVID-19.

Design, setting, and participants: Pragmatic, unblinded randomized clinical trial conducted at 21 hospitals in Canada, Kuwait, Saudi Arabia, and the US. Eligible adult patients with COVID-19 were not intubated and required oxygen (≥40%) or noninvasive ventilation. A total of 400 patients were enrolled between May 19, 2020, and May 18, 2021, and final follow-up was completed in July 2021.

Intervention: Patients were …

2022-06-06 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Unpacking Misinfodemic During A Global Health Crisis: A Qualitative Inquiry Of Psychosocial Characteristics In Social Media Interactions, Sofia M Olivares, Sahiti Myneni

Faculty, Staff and Student Publications

The pervasiveness of health information in social media has led to a modern misinformation crisis, also known as a misinfodemic. Misinfodemics have upended public health activities as clearly evident during the COVID-19 pandemic. The objective of this study is to characterize social media content and information sources using theory-driven health behavior and psychology constructs to better understand the motifs of misinformation and their role in the dissemination of health (mis)information in Twitter posts. We analyzed 1,400 randomly selected tweets related to COVID-19 to ascertain four important variables, what is the tweet about (content), how is it structured (linguistic features), who …

Latent Linguistic Motifs In Social Media Postings Resisting Covid-19 Misinformation, Tavleen Singh, Sofia Olivares, Sahiti Myneni

Faculty, Staff and Student Publications

Social media has become a predominant source of information for many health care consumers. However, false and misleading information is a pervasive problem in this context. Specifically, health-related misinformation has become a significant public health challenge, impeding the effectiveness of public health awareness campaigns and resulting in suboptimal responsiveness to the communication of legitimate risk-related information. Little is known about the mechanisms driving the seeding and spreading of such information. In this paper, we specifically examine COVID-19 tweets which attempt to correct misinformation. We employ a mixed-methods approach comprising qualitative coding, deep learning classification, and computerized text analysis to understand …

Faculty Members' Viewpoints Toward Challenges And Suggested Improvements Of Moodle Distance Learning Platform At Sultan Qaboos University During The Covid-19 Pandemic, Mohamed A. Shahat, Mohammed Al-Amri

International Journal for Research in Education

The study aimed at identifying faculty members' point of view on the challenges and suggested developments of the Sultan Qaboos University's distance learning experience in using the Moodle platform in the light of the emerging Coronavirus pandemic "COVID-19. The study has taken into consideration the faculty members’ variables (gender, teaching experience, and technological skills). The sample of the study consisted of 144 faculty members of SQU’s centers and colleges who participated voluntarily. A two-scale assessment instrument has been developed, including the challenges of distance learning and suggestions for the development of distance learning and instruction. A descriptive-analytical approach was used …

2022-06-03 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

Efficacy And Harms Of Tocilizumab For The Treatment Of Covid-19 Patients: A Systematic Review And Meta-Analysis, Alejandro Piscoya, Angela Parra Del Riego, Renato Cerna-Viacava, Jonathon Rocco, Yuani M. Roman, Angel A. Escobedo, Vinay Pasupuleti, C. Michael White, Adrian V. Hernandez

Internal Medicine Articles

INTRODUCTION: We systematically assessed benefits and harms of tocilizumab (TCZ), which is an antibody blocking IL-6 receptors, in hospitalized COVID-19 patients.

METHODS: Five electronic databases and two preprint webpages were searched until March 4, 2021. Randomized controlled trials (RCTs) and inverse probability treatment weighting (IPTW) cohorts assessing TCZ effects in hospitalized, COVID-19 adult patients were included. Primary outcomes were all-cause mortality, clinical worsening, clinical improvement, need for mechanical ventilation, and adverse events (AE). Inverse variance random-effects meta-analyses were performed with quality of evidence (QoE) evaluated using GRADE methodology.

RESULTS: Nine RCTs (n = 7,021) and nine IPTW cohorts (n = …

Governmental Persuasion Strategies On Social Media During Covid-19: A Comparative Study Of The Us And China, Fan Wang

Hatfield Graduate Journal of Public Affairs

This study compared persuasive strategies of the governments of the U.S. and China during a public health crisis using social media messages. Collecting data with R and Python from two national public health sectors' official accounts on Twitter (N = 1,630) and Sina Weibo (N = 3,554), the researcher investigated how the organizations' messages reflected Cialdini's seven principles of persuasion and whether other emergent messaging patterns occurred. According to the different phases that the two countries had gone through during the pandemic, the researcher also conducted a pooled times series analysis to investigate the relationship between the frequency of daily …

Culture: The Key To Shifting Your Organization During Post-Pandemic, Qiang Qiang

The Scholarship Without Borders Journal

Organizations are facing challenges and obstacles caused by COVID-19. After widespread vaccines, lifestyle became normal and entered the post-pandemic era. Organizational culture is the key that organizations shift during the post-pandemic. In this article, there are three recommendations that the organization can think of to make cultural changes effectively. First, the organization needs to assess and diagnose if it is an agile organization. Second, Lewin’s change model and the MCR framework can help the organization manage the changing process. Last, leadership is the key to ensuring the change is in the right direction. The leadership discussion focuses on evolutionary leadership …

“I Wonder If Being Broke Is Worth It For School”: An Investigation Of The Relationship Between Anxiety, Well-Being, And Coping Strategies Among Undergraduate Students During The Covid-19 Pandemic, Rebekah Woodburn

Bridges: An Undergraduate Journal of Contemporary Connections

This study investigated the relationship between stressors, coping strategies, and well-being among undergraduate students during the COVID-19 pandemic. Undergraduate students were asked to complete a series of measures designed to assess their general health levels, financial anxiety, subjective well-being, and resilience. In addition, they were asked open-ended retrospective questions regarding the coping strategies they had used over the course of the school year and the perceived effectiveness of these strategies. It was hypothesized that stress would be prevalent among many undergraduate students who face moderate to high anxiety levels. They would use inadequate coping strategies to improve their emotional well-being. …

Using Hospital Bed Capacity Prediction During Covid-19 To Determine Feature Importance, Helene Barrera, Justin Ehly, Blake Freeman, Chris Papesh, Brad Blanchard

SMU Data Science Review

The COVID-19 pandemic has exacerbated existing hospital capacity limitations in the United States, causing hospitals in certain regions to hit maximum capacity. The purpose of this study is to investigate key features of COVID-19 related admissions to help create a higher level of public understanding and help guide healthcare management professionals and governments when considering preventive measures. The introduction of preventative measures and new regulations during the pandemic have led to the generation of multiple types of models and feature selection methods in the field of Machine Learning that are increasingly complicated. This study focuses on the exploration of feature …

2022-06-02_Michiganoverview_Misc, Michigan Department Of Health & Human Services

Michigan COVID-19 MIS-C Data

The MIS-C Data page was obtained from Michigan's COVID-19 data page: https://www.michigan.gov/coronavirus/stats/mis-c-reporting.

This report is created by the Michigan Department of Health & Human Services from data self-reported by health care providers and local health departments. Data is updated on the first and third Thursdays of the month.

Multisystem Inflammatory Syndrome in Children (MIS-C) is a condition in children and adolescents under 21 years of age where multiple organ systems become inflamed or dysfunctional which occurs in association with illness. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, …

Sociability Moderates The Negative Association Between Covid-Related Disruptions And Life Satisfaction, Amna Khan, Katherine L. Fiori

Journal of Social, Behavioral, and Health Sciences

Disruptions in individuals’ lives during the COVID-19 pandemic have been associated with increased mental health problems and decreases in life satisfaction, although recent research indicates that these effects are not uniform across individuals. The purpose of the present study was to examine the role of sociability in moderating the association between COVID-related disruptions and life satisfaction in a sample of adults. Using data from an online survey given to N = 166 adults, COVID-19 disruptions related to conflicts with household members or roommates and disruptions in care during the pandemic were negatively associated with life satisfaction. Sociability was found to …

A New Architecture For Global Health Emergency Preparedness And Response—The Imperative Of Equity, Lawrence O. Gostin

Georgetown Law Faculty Publications and Other Works

Even before COVID-19 emerged in Wuhan, China, in December 2019, the prevailing global narrative was inequity—in health, income, race, and socioeconomic status. COVID-19 amplified all these inequities. Early in the pandemic, low-income countries were left without key medical resources, such as diagnostic tests, personal protective equipment, and ventilators. By 2021, inequitable vaccine distribution captured global attention and outrage. This year, high-income countries have bought the lion’s share of Paxlovid, a highly effective antiviral treatment. Vaccine inequities remain with only 16% of people in low-income countries having received at least 1 vaccine dose vs 80% of people across high-income countries. This …

Addressing Supervisee Anxiety During Covid-19: Applying Models Of Supervision, Deedre N. C. Mitchell, Denise B. Ebersole, Laura E. Martin

Journal of Counselor Preparation and Supervision

Graduate counseling supervisees are experiencing unprecedented obstacles, compounding stressors, and heightened anxiety amidst the global COVID-19 pandemic. If not addressed, excessive anxiety can impede professional growth and limit the competence of future counselors. While theoretical-based models of supervision exist, the application of such models has not been fully explored in relation to addressing supervisee anxiety. Prompt and pointed action is needed from counseling supervisors, who are professionally and ethically responsible for training future counselors and the gatekeeping process. Three supervision models, including the Integrative Developmental Model, Solution-Focused Supervision, and Cognitive-Behavioral Supervision, are utilized to address heightened anxiety among counseling supervisees. …

The Effects Of Covid-19 On Counselor-In-Training Resilience: A Case Study, Anthony L. Suarez, Alishia Elliott, Bonni A. Behrend, Chris L. Carver

Journal of Counselor Preparation and Supervision

Contemporary literature in counseling suggests that resilience is a protective factor in preventing burnout among counselors and counselors-in-training. The strategies that counseling students have historically relied on to learn resilient habits have been disrupted by the COVID-19 pandemic, but the implications for students are still unknown. This qualitative case study examined the impact of the COVID-19 pandemic on 17 counselors-in-training, their adjustments through a resilience lens, and students’ perspectives on the response of their program in support of pandemic-related challenges. Findings of the current study pinpoint specific causes of counseling students’ psychological distress, as well as the social and academic …

Engaged Trauma Training Through Role-Play Observations During Covid-19, Emily Horton, Claudia G. Interiano-Shiverdecker, Crystal L. Hughes, Mica Stumpf

Journal of Counselor Preparation and Supervision

This phenomenological investigation explored counselors'-in-training experiences while observing role-plays of trauma-specific cases. Three themes emerged: (a) learning to be a trauma counselor, (b) growth as counselors-in-training, and (c) connection and engagement through multiple delivery methods. The findings from this study showed that observing role-plays can be an efficacious teaching approach in trauma counseling courses. Findings also suggest that integrating role-plays into trauma curricula helped students understand the complexity of trauma, increase self-competency, self-efficacy, and emotional intelligence, and engage with the content in face-to-face and online formats. The authors provide a further discussion on implications for counselor education and …

The Pandemic And Privacy: The Global Culture Of Intrusion, Jon L. Mills, Lucca Viana, Danielle Black

Legislation and Policy Brief

No abstract provided.

Hired During Covid: Interviewing And Onboarding In A Pandemic, Roslyn Grandy, Lauren M. Fletcher, Faythe Thurman, Rachel Whitney

Faculty & Staff Scholarship

The pandemic forced those working in higher education to navigate a myriad of changes in all facets of day-to-day operations. From January-February 2022, we conducted a study that surveyed hiring managers for professional academic library positions to identify how the COVID-19 pandemic has affected their hiring and onboarding processes. We will present our preliminary findings from the mixed-methods survey in advance of a published article. Our study identifies changes in hiring practices and reflects the current attitudes of hiring managers in regards to future employment practices.

Because many interview processes have transitioned to an online format, some hiring managers are …

Consumer Protection Of Persons With Disabilities Amidst The Covid-19, James Keith C. Heffron

Center for Business Research and Development

The Persons with Disabilities (PWD) sector was one of the most overlooked and affected sectors during the COVID-19 pandemic. As consumers, PWDs have suffered difficult challenges in the access of essential goods and services, including healthcare, and these challenges have been unduly aggravated because of the crisis. The article exposes and examines the negative impact of the crisis on the consumer rights and behavior of PWDs with a special focus on the novel barriers brought about by the pandemic on their right to access. The current pre-pandemic legislation is not adequate to protect PWDs from these novel barriers as there …

Changes In Teachers’ Mobility And Attrition In Arkansas During The First Two Years Of The Covid-19 Pandemic, Andrew Camp, Gema Zamarro, Josh B. Mcgee

Education Reform Faculty and Graduate Students Publications

The COVID-19 pandemic has been a trying period for teachers. Teachers had to adapt to unexpected conditions, teaching in unprecedented ways. As a result, teachers' levels of stress and burnout have been high throughout the pandemic, raising concerns about a potential increase in teacher turnover and future teacher shortages. We use administrative data for the state of Arkansas to document the effects of the COVID-19 pandemic on teachers’ mobility and attrition during the years 2018-19 to 2021-2022. We find stable turnover rates during the first year of the pandemic (2020-2021) but an increase in teacher mobility and attrition in the …

2022-06-01 Michiganoverview_Covidbedppe, Michigan Department Of Health & Human Services

Michigan COVID-19 Hospital Data

Contains the tables Statewide Hospital Capacity Report for COVID-19, COVID-19 Metrics, Statewide Hospital Available PPE Tracking for COVID-19, as well as the tables PPE Days On Hand and Patient Census.

2022-06-01_Michiganoverview_Covidstats, Michigan Department Of Health & Human Services

Cumulative Michigan COVID-19 Data

The COVID Overview page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/stats.

The State of Michigan is working around the clock to test and treat COVID-19 patients. Below is the most recent data healthcare experts across the state have compiled. COVID case and testing data will be posted once a week on Wednesdays.

This report is provisional and subject to change. City of Detroit and Wayne County are reported separately. MDHHS began tracking probable cases April 5, 2020. FCI indicates federal correctional institute. MDOC indicates Michigan Department of Corrections. Diagnostic tests, including nucleic acid amplification/real-time polymerase chain reaction (NAAT/RT-PCR) …

Association Between Early Cumulative Fluid Balance And Successful Liberation From Invasive Ventilation In Covid-19 Ards Patients - Insights From The Provent-Covid Study: A National, Multicenter, Observational Cohort Analysis, Sanchit Ahuja, Harm-Jan De Grooth, Frederique Paulus, Fleur L. Van Der Ven, Ary Serpa Neto, Marcus J. Schultz, Pieter R. Tuinman

Anesthesiology Articles

BACKGROUND: Increasing evidence indicates the potential benefits of restricted fluid management in critically ill patients. Evidence lacks on the optimal fluid management strategy for invasively ventilated COVID-19 patients. We hypothesized that the cumulative fluid balance would affect the successful liberation of invasive ventilation in COVID-19 patients with acute respiratory distress syndrome (ARDS).

METHODS: We analyzed data from the multicenter observational 'PRactice of VENTilation in COVID-19 patients' study. Patients with confirmed COVID-19 and ARDS who required invasive ventilation during the first 3 months of the international outbreak (March 1, 2020, to June 2020) across 22 hospitals in the Netherlands were included. …

Analysis Of Blood Type For Sars-Cov-2 And Correlation For Disease Acquisition In Various Sociodemographic Groups Including Women Of Childbearing Age., Maria L. Vacca, Nikunj Vyas, Joshua Banks, Elaine Joyce, Cindy Hou, Benjamin E. Leiby, Stefanie Deangelo, Todd P. Levin, Autum Shingler-Nace, Marilyn Mapp, Ashlee Hiester, Jonathan H. Coughenour

Division of Infectious Diseases and Environmental Medicine Faculty Papers

BACKGROUND: Multiple studies have occurred to determine if a patient's blood type, Rhesus factor (Rh), and sociodemographic attributes contribute to contracting SARS-CoV-2. True association remains unknown.

METHODS: Inclusion criteria included in-patients who were tested for SARS-CoV-2 with blood type assessed. Study endpoints combined ABO, Rh and all-cause inpatient mortality (ACIM) with testing positivity. Pregnancy status was one of several secondary endpoints evaluated. A logistic regression analysis was used to estimate association.

RESULTS: Of the 27,662 patients who met inclusion criteria, Type A blood was associated with increased positivity [1.01 (1.0-1.21), P = .03]. Type B [1.10 (0.99-1.23), P = .08] …

2022-06-01_Michiganoverview_Covidvaccinestats, Michigan Department Of Health & Human Services

Michigan COVID-19 Vaccine Data

The COVID Vaccine Dashboard page was obtained from Michigan's main COVID-19 page: https://www.michigan.gov/coronavirus/resources/covid-19-vaccine/covid-19-dashboard.

First-dose tracker above is for entire Michigan Population. Coverage maps below are for age 5+.

Previously reported numbers of administered vaccine doses may change as new data are received. A possible lag in reporting vaccine doses will result in increases in numbers previously reported.

This report is created by the Michigan Department of Health and Human Services Division of Immunization from data reported to the Michigan Care Improvement Registry (MCIR).

The dashboard contained the tabs Primary Series Doses Administered, Primary Series Doses by Vaccine, …