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Articles 1201 - 1230 of 5684
Full-Text Articles in Entire DC Network
The Lived Experiences Of School Counselors Related To Natural Disaster Trauma, Jennifer Baxley Bellinger
The Lived Experiences Of School Counselors Related To Natural Disaster Trauma, Jennifer Baxley Bellinger
Doctoral Dissertations and Projects
The purpose of this hermeneutic phenomenological study was to understand and describe the lived experiences of school counselors in South Carolina regarding natural disaster trauma and their perceptions regarding their ability to work effectively with students during and after disasters. The experiences of school counselors regarding their perceptions of effectiveness when working with students both during and after natural disasters prior to this study were unknown. The American School Counselor Association (ASCA) Model provided the framework for this study as it outlines the necessary preparation for and execution of a school counselor’s work with students, while Herman’s trauma theory and …
Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information: Does Political Affiliation Impact Levels Of Situational Empathy?, Keira N. Mills, Kaylee Ries, Beth Durkin, Abby Braden, Wesley Barnhart
Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information: Does Political Affiliation Impact Levels Of Situational Empathy?, Keira N. Mills, Kaylee Ries, Beth Durkin, Abby Braden, Wesley Barnhart
Honors Projects
Psychophysical numbing, compassion fading, and the singularity effect are strongly affecting the world amidst the COVID-19 pandemic. Empathy-motivated prosocial behavior is not consistent with the drastic number of lives lost due to COVID-19. The current study evaluated participants for situational empathy levels post-exposure to either COVID-19 death statistics or a personal reflection on loss due to COVID-19. Alongside empathy, political affiliation and COVID-19 personal loss were measured as potential moderators on the relationship between medium of exposure to mortality information and empathy levels in the sample.
Comparing Levels Of Situational Empathy Based On Medium Of Exposure To Covid-19 Mortality Information And Vaccination Status, Kaylee Ries
Honors Projects
Psychophysical numbing, compassion fading, and the singularity effect are strongly affecting the world amidst the COVID-19 pandemic. Empathy motivated prosocial behavior is not consistent with the drastic number of lives lost due to COVID-19. The current study evaluated participants for situational empathy levels post exposure to either COVID-19 death statistics or a personal reflection on loss due to COVID-19. Alongside empathy, vaccination status was measured as a potential moderator on the relationship between medium of exposure to mortality information and empathy levels in the sample. 68 students were considered for this study. There was not a significant relationship between situational …
Comparing The Experience Of Pre-Service Teachers In The First And Final Semesters In Online Learning Using A Focus Group Study, Suyatno Suyatno, Sibawaihi Sibawaihi, Wantini Wantini, Dzihan Khilmi Ayu Firdausi, Lilis Patimah
Comparing The Experience Of Pre-Service Teachers In The First And Final Semesters In Online Learning Using A Focus Group Study, Suyatno Suyatno, Sibawaihi Sibawaihi, Wantini Wantini, Dzihan Khilmi Ayu Firdausi, Lilis Patimah
The Qualitative Report
Since the outbreak of COVID-19, online learning has become the innovation and an alternative virtual education adopted by universities, due to campus closures. The sudden adoption of the innovation without prior preparation and training causes the ineffective implementation of online learning in most institutions. Based on this description, insufficient information is available regarding the experiences of the student population, which are the most affected by online learning in higher education. Therefore, this study aims to explore the experiences of pre-service teachers regarding their numerous abilities to provide a good online learning program. Using a qualitative focus group study design, data …
A Pharmacoepidemiological Study Of Myocarditis And Pericarditis Following The First Dose Of Mrna Covid-19 Vaccine In Europe, Joana Tome, Logan Cowan, Isaac Fung
A Pharmacoepidemiological Study Of Myocarditis And Pericarditis Following The First Dose Of Mrna Covid-19 Vaccine In Europe, Joana Tome, Logan Cowan, Isaac Fung
Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications
This study assessed the myocarditis and pericarditis reporting rate of the first dose of mRNA COVID-19 vaccines in Europe. Myocarditis and pericarditis data pertinent to mRNA COVID19 vaccines (1 January 2021–11 February 2022) from EudraVigilance database were combined with European Centre for Disease Prevention and Control (ECDC)’s vaccination tracker data. The reporting rate was expressed as events (occurring within 28 days of the first dose) per 1 million individuals vaccinated. An observed-to-expected (OE) analysis quantified excess risk for myocarditis or pericarditis following the first mRNA COVID-19 vaccination. The reporting rate of myocarditis per 1 million individuals vaccinated was 17.27 (95% …
Virtual Visits In Routine Prenatal Care, Katrina K. Wu
Virtual Visits In Routine Prenatal Care, Katrina K. Wu
MUSC Theses and Dissertations
Problem
One million pregnant persons in the United States do not receive early prenatal care or the recommended number of prenatal visits each year, and this gap in care access disproportionately affects people of color, those with lower incomes, and those living in rural communities. Telemedicine was widely utilized in prenatal care during the COVID-19 pandemic, and optimizing prenatal telemedicine has the potential to improve prenatal care access beyond the pandemic.
Purpose
This dissertation focused on examining the integration of virtual visits in routine prenatal care during the COVID-19 pandemic. The purpose of this dissertation was to:
Aim 1. Explore …
The Effects Of The Covid-19 Pandemic And Online Learning On Teacher Morale And What That Means For Students: A Systematic Review Of The Literature, Madison Thomas
Honors Theses
Teacher shortages have occurred in the United States over the past ten years and continue to rise (Darling-Hammond & Podolsky, 2019). Teacher shortages have continued to rise at an increased rate since the onset of the COVID-19 pandemic. Since 2020, multiple studies have addressed teacher morale and retention in the wake of a global pandemic (Matthews et al., 2022; Bill et al., 2022). Through a systematic review of the literature from the last three years, this review explored the factors most affecting teacher morale and retention in Michigan following the pandemic. The keywords used within the literature review were: teacher …
The Role Of School-Home Communication In Supporting The Development Of Children’S And Adolescents’ Digital Skills, And The Changes Brought By Covid-19, Mai Beilmann, Signe Opermann, Veronika Kalmus, Joyce Vissenberg, Margus Pedaste
The Role Of School-Home Communication In Supporting The Development Of Children’S And Adolescents’ Digital Skills, And The Changes Brought By Covid-19, Mai Beilmann, Signe Opermann, Veronika Kalmus, Joyce Vissenberg, Margus Pedaste
Journal of Media Literacy Education
School-home communication is a growing research field in social sciences, particularly in education sciences and communication studies. While previous studies have paid much attention to the importance of school-home interaction in supporting primary academic socialisation and progress of elementary school pupils, the role of teacher-parent communication and collaboration in influencing the development of children’s and adolescents’ digital skills remains an under-researched area. This paper employed thematic analysis of in-depth interviews with education experts in six European countries, providing an insight into their opinions and views on the problems in communication between homes and schools. The analysis identified main problems in …
Rural Entrepreneurs Under Fire: Pandemic Reveals Need For Collaboration And Support, Jacob A. Dolence, James C. Haug
Rural Entrepreneurs Under Fire: Pandemic Reveals Need For Collaboration And Support, Jacob A. Dolence, James C. Haug
Journal of Business & Entrepreneurship
This article summarizes a research study done from April 2020 until April 2021 to examine the challenges, response, and tactics, of entrepreneurs in rural southern Virginia. In particular, the research goes into depth of how the COVID-19 pandemic effected operations, how entrepreneurs responded, and what measures they took to stay viable. Finally, the article proposes a framework for rapid response in the case of future pandemics, natural disasters, or economic events that cause similar disruptions.
2023-04-18_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services
2023-04-18_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services
Michigan COVID-19 Syndromic Surveillance System Data
The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "Coronavirus Symptoms": https://www.michigan.gov/coronavirus/stats/coronavirus-symptoms. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated twice a week on Mondays and Thursdays.
Syndromic Surveillance System data is obtained from approximately 216 facilities participating in syndromic surveillance (139 Emergency Departments (ED), 77 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, …
The Reality Of Teaching English Virtually: Esl Teachers' Perspectives And Experiences During The Covid-19 National Pandemic, Natalia Guerrero
The Reality Of Teaching English Virtually: Esl Teachers' Perspectives And Experiences During The Covid-19 National Pandemic, Natalia Guerrero
LSU Doctoral Dissertations
This study examined the dilemma ESL teachers experienced as the educational system shifted from the usual modus operandi of in-person lessons to the uncharted virtual learning environment (VLE). ESL teachers, in one of the largest urban districts in Louisiana, accumulated additional roles and responsibilities that were unique to the teachers of the English learner (EL) population enrolled at their schools.
Data collected to answer the research questions were the product of single and focus group’s interviews with five ESL elementary and middle school teachers in Freedom District. State and district emergency response to COVID-19 guidelines, along with instructional artifacts, were …
Covid-19: Visualized Qualitative Aviation Research Themes, Chien-Tsung Lu, Huabo Sun
Covid-19: Visualized Qualitative Aviation Research Themes, Chien-Tsung Lu, Huabo Sun
Journal of Aviation Technology and Engineering
The purpose of this study is to review pandemic-related publications that help the aviation industry cope with pandemic outbreaks like that of COVID-19. Published documents were searched and downloaded from academic libraries including Web of Science for a qualitative analysis. After the triangulation of publications for decisionmakers, and researchers, all important research clusters were visually generated based on the VOSviewer process. Some research clusters were further discussed for a thorough understanding of existing research perspectives. The result discovered that wearing a face mask and vaccination have been the two most effective means to counteract pandemic outbreaks. Additional findings were extracted …
Covid-19'S Effects On Students' Educational Growth, Anna Chavez Maples
Covid-19'S Effects On Students' Educational Growth, Anna Chavez Maples
Departmental Honors & Graduate Capstone Projects
The Coronavirus Disease 2019 (COVID-19) pandemic has affected the education system drastically and created many challenges for families as well as schools. When schools moved to online and virtual learning, many students began to fall behind in their education and the Every Student Succeeds Act (ESSA) became harder for schools to meet. The following research explored the effects the pandemic caused in schools and how far behind students are today with their education and socialization. The results of this research will share ways to help today’s students catch up in their education so that they can reach their full potential.
Increasing Covid-19 Vaccination Coverage For Newcomer Communities: The Importance Of Disaggregation By Language, Abigail Steiner, Kristine Knuti Rodrigues, Nadège Mudenge, Janine Young, Rasulo Rasulo, Colleen Payton, Malini Desilva, Jeremy Michel, Mary Fabio, Katherine Yun
Increasing Covid-19 Vaccination Coverage For Newcomer Communities: The Importance Of Disaggregation By Language, Abigail Steiner, Kristine Knuti Rodrigues, Nadège Mudenge, Janine Young, Rasulo Rasulo, Colleen Payton, Malini Desilva, Jeremy Michel, Mary Fabio, Katherine Yun
College of Population Health Faculty Papers
The COVID-19 pandemic has disproportionately affected refugee, immigrant, and migrant populations. Vaccines are essential for decreasing transmission and severity of COVID-19 infection. Understanding differences in vaccination coverage based on preferred language is crucial for focusing efforts to decrease COVID-19-related disparities. Four sites in the Minnesota Center of Excellence in Newcomer Health collaboratively evaluated completion of primary COVID-19 vaccination series on or before December 31, 2021, for patients who were 12 years or older on June 30, 2021, by preferred language. The non-English/non-Spanish speaking population included 46,714 patients who spoke 174 languages; COVID-19 vaccination coverage by language ranged from 26.2% to …
The Unreasonableness Of Reasonable: Rethinking The Reasonable Investor Standard, Alexandra Li
The Unreasonableness Of Reasonable: Rethinking The Reasonable Investor Standard, Alexandra Li
Northwestern University Law Review
This Note explores the “reasonable investor” standard in light of recent developments in pandemic-era securities litigation. Scholars have long criticized the reasonable investor standard for determining materiality. Given the dramatic backdrop of the COVID-19 pandemic, the limitations of the standard are becoming ever more evident. This Note provides a brief history of the development of the current standard and highlights some of its problems through two recent COVID-19 securities fraud cases. This Note argues that the reasonable investor standard is no longer sufficient to protect investors. Through examining tort law and First Amendment jurisprudence, this Note differentiates between the “reasonable” …
Liberating Legal Aid: Reducing Covid-19'S Justice Gap And Promoting Health By Removing The Legal Services Corporation's Class Action And Advocacy Restrictions, Molly C. Schmidt
Liberating Legal Aid: Reducing Covid-19'S Justice Gap And Promoting Health By Removing The Legal Services Corporation's Class Action And Advocacy Restrictions, Molly C. Schmidt
Cleveland State Law Review
The Legal Services Corporation (LSC) is the single-largest funder of civil legal services, or legal aid, in the United States. The COVID-19 pandemic underscored a longstanding and growing problem faced by ow-income Americans served by LSC-funded legal aid organizations: the growing "justice gap." The justice gap represents the unmet civil legal needs of low-income Americans. The justice gap perpetuates poverty, conceals health-harming legal problems, and furthers racial disparities. Despite the LSC’s essential role in reducing the justice gap and promoting “equal access to justice,” Congress consistently underfunded the LSC before and during COVID-19. Congress has also prohibited the LSC-funded legal …
Higher Education Students’ Perceptions Of Online Learning During The Covid-19 Pandemic, Abby O’Bryant
Higher Education Students’ Perceptions Of Online Learning During The Covid-19 Pandemic, Abby O’Bryant
Butler Journal of Undergraduate Research
This article focuses on the impacts of online learning during the COVID-19 pandemic on students at the University of Hawai‘i at Hilo. Using survey data (n = 64) and semistructured interviews with currently enrolled students (n = 17), key impacts of online learning on the student body were analyzed. The respondents reported disengagement in lectures, negative impacts on their mental and physical health, negative thoughts about dropping out and transferring, apprehension about the quality of course content, and dissatisfaction with tuition. The paper utilizes qualitative data analysis to report the findings.
Chronic Disease Self-Management Of Post-Acute Sequelae Of Covid-19 Among Older Adults: A Mixed-Methods Analysis., Kamilah Thomas-Purcell, Rosemary Davenport, Victoria Ayala, Donrie Purcell, Raymond L. Ownby
Chronic Disease Self-Management Of Post-Acute Sequelae Of Covid-19 Among Older Adults: A Mixed-Methods Analysis., Kamilah Thomas-Purcell, Rosemary Davenport, Victoria Ayala, Donrie Purcell, Raymond L. Ownby
HPD Articles
INTRODUCTION: Approximately 20-30% of individuals who contract acute coronavirus disease (COVID-19) infection develop longer term complications of their initial infection, referred to as Post-Acute Sequelae of SARS-CoV-2 infection (PASC). PASC is characterized by chronic, varying symptomatology.
METHODS: Using a mixed methods study design, we aimed to gain insight into individuals' experience with PASC, including cognitive issues, fatigue, and sleep disturbances. We explored whether our previously developed application (app), aimed at improving self-management skills among individuals with chronic diseases, is relevant for individuals with PASC and gained information to adapt the app for individuals with PASC. The study included 19 individuals, …
Covid-19 Related Biliary Injury: A Review Of Recent Literature, Sujani Yadlapati, Simone A. Jarrett, Daniel Baik, Adib Chaaya
Covid-19 Related Biliary Injury: A Review Of Recent Literature, Sujani Yadlapati, Simone A. Jarrett, Daniel Baik, Adib Chaaya
COVID-19 Papers, Posters, and Presentations
Since its emergence in 2019, it has become apparent that coronavirus 2019 (COVID-19) infection can result in multi systemic involvement. In addition to pulmonary symptoms, hepatobiliary involvement has been widely reported. Extent of hepatic involvement ranges from minor elevation in liver function tests (LFTs) to significant hepatocellular or cholestatic injury. In majority of cases, resolution of hepatic injury or improvement in LFTs is noted as patients recover from COVID-19 infection. However, severe biliary tract injury progressing to liver failure has been reported in patients requiring prolonged intensive care unit stay or mechanical ventilation. Due to the timing of its presentation, …
A Phenomenological Study Of The Lived Experiences Of New Mexico Charter Leaders Through The Covid-19 Pandemic, Nadine T. Torres
A Phenomenological Study Of The Lived Experiences Of New Mexico Charter Leaders Through The Covid-19 Pandemic, Nadine T. Torres
Teacher Education, Educational Leadership & Policy ETDs
The pandemic caused by the COVID-19 virus has impacted the educational landscape in unbelievable ways. The changes to the learning environment in schools required leaders to obtain and exercise different competencies. New Mexico charter leaders are leading in the new normal of public education. With the additional roles, requirements, and expectations brought on by the pandemic, leaders cannot return to their prior leadership practices. The purpose of this qualitative hermeneutic phenomenological study was to understand and give voice to the lived experiences of NM charter leaders working through the COVID-19 pandemic. The narrative of the participants highlighted four major themes: …
Explicit Social And Emotional Learning In Elementary Education In The Post-Covid-19 Era, Mitch Mox
Explicit Social And Emotional Learning In Elementary Education In The Post-Covid-19 Era, Mitch Mox
Masters Projects
The COVID-19 pandemic has exacerbated already dire situations in schools regarding students' social and emotional well-being. A growing body of research within the last five years supports the implementation of social emotional learning (SEL) in schools to better the academic and emotional growth of students, especially in the wake of a global pandemic that disrupted their social lives. Research not only suggests that students need increased exposure to explicit SEL curricula, but that states need to do more to educate districts and teachers on the importance of SEL. Additionally, studies suggest that districts need to develop ways of assessing and …
Transition To Distance Learning: Student Experience And Communication During The Covid-19 Pandemic In The United Arab Emirates, Soumaya Abdellatif, Aizhan Shomotova, Safouane Trabelsi, Salwa Husain, Najeh Alsalhi, Mohamed Eltahir
Transition To Distance Learning: Student Experience And Communication During The Covid-19 Pandemic In The United Arab Emirates, Soumaya Abdellatif, Aizhan Shomotova, Safouane Trabelsi, Salwa Husain, Najeh Alsalhi, Mohamed Eltahir
All Works
The COVID-19 pandemic in 2020 prompted higher education institutions in the United Arab Emirates (UAE) to switch to online learning for the safety of their citizens. The main purpose of this study is to determine the relationship between four indicators of digital learning experience and the intensity of student socio-pedagogical communication after the transition to distance learning. The data were collected from Ajman University, a private university in the UAE, during the spring of 2020. The sample consisted of 381 students who were surveyed using an online survey tool or email. First, this study found that the majority of students …
Teacher Turnover During The Covid-19 Pandemic, Andrew Camp, Gema Zamarro, Josh B. Mcgee
Teacher Turnover During The Covid-19 Pandemic, Andrew Camp, Gema Zamarro, Josh B. Mcgee
Education Reform Faculty and Graduate Students Publications
Teachers' levels of stress and burnout have been high throughout the COVID-19 pandemic, raising concerns about a potential increase in teacher turnover and future teacher shortages. We examine how the COVID-19 pandemic affected teacher turnover in Arkansas from 2018-19 to 2022-23 using administrative data. We find no major changes in turnover entering the first two pandemic years, but a large increase of 5.3 percentage points (26%) entering the third year, with variation by teacher and student characteristics. We also find that increases in teacher turnover are related to instructional mode and that this turnover may partially be explained by the …
Internet Usage During And Post Covid-19 Pandemic: A Study On The Students Of Information Science And Library Management In The University Of Rajshahi, Bangladesh., Zihadur Rahman, Md. Armanul Haque, Dil Afroz Bente Aziz
Internet Usage During And Post Covid-19 Pandemic: A Study On The Students Of Information Science And Library Management In The University Of Rajshahi, Bangladesh., Zihadur Rahman, Md. Armanul Haque, Dil Afroz Bente Aziz
Library Philosophy and Practice (e-journal)
Abstract
Purpose
The COVID-19 epidemic significantly impacted daily life and led to the adoption of significant steps to stop the virus's spread. Educational institutions and social gatherings were placed on prolonged lockdown, with people continuing to maintain physical distance. As a result, students of all classes are highly engaged in using the internet. In this article, the usage of the internet of the student's Information Science and Library Management, University of Rajshahi are studied. The aim of the present study was to examine the usage of the internet during the post-pandemic. Furthermore, this research aims to investigate the internet usage …
Metabolic Dysregulation Impairs Lymphocyte Function During Severe Sars-Cov-2 Infection, Sanjeev Gurshaney, Anamaria Morales-Alvarez, Kevin Ezhakunnel, Andrew Manalo, Thien-Huong Huynh, Jun-Ichi Abe, Nhat-Tu Le, Daniela Weiskopf, Alessandro Sette, Daniel S Lupu, Stephen J Gardell, Hung Nguyen
Metabolic Dysregulation Impairs Lymphocyte Function During Severe Sars-Cov-2 Infection, Sanjeev Gurshaney, Anamaria Morales-Alvarez, Kevin Ezhakunnel, Andrew Manalo, Thien-Huong Huynh, Jun-Ichi Abe, Nhat-Tu Le, Daniela Weiskopf, Alessandro Sette, Daniel S Lupu, Stephen J Gardell, Hung Nguyen
Faculty, Staff and Student Publications
Cellular metabolic dysregulation is a consequence of SARS-CoV-2 infection that is a key determinant of disease severity. However, how metabolic perturbations influence immunological function during COVID-19 remains unclear. Here, using a combination of high-dimensional flow cytometry, cutting-edge single-cell metabolomics, and re-analysis of single-cell transcriptomic data, we demonstrate a global hypoxia-linked metabolic switch from fatty acid oxidation and mitochondrial respiration towards anaerobic, glucose-dependent metabolism in CD8+Tc, NKT, and epithelial cells. Consequently, we found that a strong dysregulation in immunometabolism was tied to increased cellular exhaustion, attenuated effector function, and impaired memory differentiation. Pharmacological inhibition of mitophagy with mdivi-1 reduced excess glucose …
A Phenomenological Study Of Parents Accessing And Receiving Professional Care For Their Child With Autism Spectrum Disorder (Asd) During The Covid-19 Outbreak In Washington State, Patrick Michael Barry
A Phenomenological Study Of Parents Accessing And Receiving Professional Care For Their Child With Autism Spectrum Disorder (Asd) During The Covid-19 Outbreak In Washington State, Patrick Michael Barry
Doctoral Dissertations and Projects
COVID-19 changes and restrictions have necessitated a change in the way schools, mental health providers, medical providers, and other educational and therapy services provide for children with autism. This study explores, in-depth, the experience of parents of children with ASD as they have navigated the COVID-19 required changes to professional treatment and services for children with ASD and their families. Research suggests that raising a child with an autism spectrum disorder (ASD) can be an overwhelming experience for parents and families, and greater family burden is positively associated with the number of unmet professional help service needs. As services were …
K-12 Florida Christian Schools In Crisis: A Correlational Study Of Educational Leadership During The Covid-19 Pandemic, Cesar O. Irizarry
K-12 Florida Christian Schools In Crisis: A Correlational Study Of Educational Leadership During The Covid-19 Pandemic, Cesar O. Irizarry
Doctoral Dissertations and Projects
K-12 Florida Christian schools were disrupted due to the advent of a global crisis brought about by the COVID-19 pandemic. Flexibility was needed by educational leadership during this time of crisis. For that reason, this study will aim to understand the leadership principles necessary to provide leaders with the flexibility to adapt to extreme circumstances. The literature addresses the leader’s importance of being flexible during a crisis (Ruffner & Huizing, 2016). However, the literature continues to examine the effects of the pandemic on education but has not identified those contingencies that are necessary for leaders in the Christian educational system …
Understanding An Urban Black Worldview: A Phenomenological Examination Of 2020, Gershwin Francis Grant
Understanding An Urban Black Worldview: A Phenomenological Examination Of 2020, Gershwin Francis Grant
Doctoral Dissertations and Projects
This action research project was designed to surface and codify a worldview that emerged among black people as a result of the traumatic phenomena of 2020. The program sought to help white pastors in New York’s Lower Hudson Valley recognize this new worldview, understand its implications, and desire to intentionally develop their level of Cultural Competence to more effectively counsel and disciple black congregants holding this worldview. The detrimental effects of the phenomena of 2020 exacerbated existing trauma caused by social and institutional racism and resulted in an altered worldview among urban blacks affecting relationships in communities and within church …
Factor Xa Cleaves Sars-Cov-2 Spike Protein To Block Viral Entry And Infection, Wenjuan Dong, Sean P J Whelan, Et Al.
Factor Xa Cleaves Sars-Cov-2 Spike Protein To Block Viral Entry And Infection, Wenjuan Dong, Sean P J Whelan, Et Al.
2020-Current year OA Pubs
Serine proteases (SP), including furin, trypsin, and TMPRSS2 cleave the SARS-CoV-2 spike (S) protein, enabling the virus to enter cells. Here, we show that factor (F) Xa, an SP involved in blood coagulation, is upregulated in COVID-19 patients. In contrast to other SPs, FXa exerts antiviral activity. Mechanistically, FXa cleaves S protein, preventing its binding to ACE2, and thus blocking viral entry and infection. However, FXa is less effective against variants carrying the D614G mutation common in all pandemic variants. The anticoagulant rivaroxaban, a direct FXa inhibitor, inhibits FXa-mediated S protein cleavage and facilitates viral entry, whereas the indirect FXa …
Now What?, David L. Hart Jr, Rebecca J. Armstrong
Now What?, David L. Hart Jr, Rebecca J. Armstrong
FDLA Journal
NOW WHAT?
David Hart, Ph.D. and Rebecca Armstrong, Ph.D.
Making the decision to pursue an advanced degree is certainly commendable. To add to one’s knowledge base is ambitious and the results of such a commitment are monumental. However, it goes without saying that in that scheme, life’s challenges are ever-present, and along with other given responsibilities, the concept of time becomes a faded memory. If that is not enough, COVID-19 presented all degree-seekers with issues that seemed insurmountable. Many decided that virtual learning programs would provide an environment that allowed for success in the academic arena despite the forces that …