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2025 - 2026 Faculty Senate Annual Report, University Of South Carolina

Faculty Senate

The primary file includes the 2025 - 2026 Admissions Committee Report. Additional annual reports are attached.

Copyright Eligibility For Ai Works Under United States Law, Roger V. Skalbeck

Law Faculty Publications

This article examines copyright eligibility for works that incorporate generative AI elements under United States law, explaining that such works may be protected only to the extent they contain human-authored expression.  This expression can appear as creative selection, arrangement, editing, or other expressive contributions, while unedited or autonomously generated AI output is not copyrightable. The article highlights how the U.S. Copyright Office’s registration and review system, through disclosure requirements, refusals, and public registration records, creates meaningful evidence about boundaries of copyright protection for AI-assisted works. The article contrasts this U.S. registration framework with other legal systems, including European jurisdictions such …

Dismantling The Whiteness Of Legal Education, Doron Samuel-Siegel

Law Faculty Publications

Whiteness is not merely a racial description. Whiteness operates as allegiance to structural racism. The quiet engine of racial hierarchy, whiteness pervades and shapes traditional legal education, rendering legal pedagogy a structurally racist enterprise. Legal education not only reproduces the racism embedded in the law and legal profession, but also obscures the ways legal doctrine, professional norms, and pedagogical practices normalize, protect, and make invisible the advantages that accrue to whiteness itself. In doing so, itproduces lawyers ill-equipped to dismantle structural injustice.

This Article breaks new ground in the scholarship on legal pedagogy by defining whiteness as it operates within …

Two Cheers For Cox V. Sony, James Gibson

Law Faculty Publications

There’s a lot to dislike about the Supreme Court’s opinion in Cox Communications, Inc. v. Sony Music Entertainment. It mischaracterizes, oversimplifies, and ignores precedent. It fails to engage with important arguments. It mangles the meaning of “intent.” And it introduces uncertainty into the workings of secondary liability across other intellectual property regimes.

For these reasons, the decision doesn’t deserve three cheers. But it deserves two. Because in two important ways, the Supreme Court has succeeded. First, the opinion fixes some misguided appellate court holdings by articulating a relatively workable standard for future copyright cases involving secondary liability. Second, despite …

Leadership Through Belonging: Community Engagement As The Hidden Engine Of Purpose-Driven Leadership, Lina Safa

GSEP Research Symposium

Leadership scholarship increasingly recognizes that effective leadership extends beyond individual competence to include relational, cultural, and community-based dimensions. Yet, the role of belonging as a foundational mechanism shaping leadership identity and community engagement remains underexplored. Drawing on qualitative data from a study of Lebanese women leaders in higher education, this work examines how experiences of belonging, within families, institutions, and professional communities, serve as a developmental engine for purpose-driven leadership and sustained community engagement.

Wellness4kids: An Integrated Mental Health Education And Movement-Based Model For Building Resilience In Youth, Ashinee Reynolds, Chelsi Ferguson

GSEP Research Symposium

Children today are experiencing rising rates of anxiety, peer conflict, and emotional distress, yet many lack access to preventative mental health services. Wellness4Kids (formerly Move & Shine) is an integrated program model that pairs mental health education and social-emotional learning with movement based, experiential activities to build coping skills and resilience in youth before crises emerge. This program model is guided by three research questions concerning emotional awareness and long-term coping skill development. The program has been implemented across diverse community and school settings in California, Missouri, and Belize, reaching more than 3,458 students to date. The evaluation combined program …

The Obverse-Turing Test: Rethinking Authorship, Trust, And Time In An Accelerated Age, Michael J. Miller, Chatgpt (Ai~Nesbo+)

Psychology

In this paper, we propose a new test for scientific accountability in the era of artificial intelligence: the Obverse Turing Test for Authorship. While the traditional Turing test focuses on a machine's ability to mimic human intelligence, our test addresses the question: when should a scientific contribution involving artificial intelligence be attributed joint authorship? We argue that more and more authors are using AI in the idea generation and elaboration stages of their work, but rarely acknowledge this use explicitly. To examine this gap, we analyze examples of human–AI interactions across fields and propose a new approach to authorship based …

Multimodal Characterization Of Intracranial Biomechanics In A 3d Biofidelic Head Surrogate, Ahmed A. Alshareef, J. Sebastian Giudice, Daniel F. Shedd, Yuan-Chiao Lu, Curtis L. Johnson, Dzung L. Pham, Matthew B. Panzer

Faculty Publications

Rapid head motion causes the brain to deform, which may lead to acute and chronic consequences to normal brain health and function. Since the risk and severity of brain injury correlates with brain strain, computational and physical models of the brain response to impact are commonly used to assess risk and evaluate safety devices in silico. Most physical head surrogates that are used for equipment evaluation, however, are simplified and lack internal measures of brain deformation, relying instead on the interpretation of the resulting head kinematics to predict injury. Developing a more biofidelic physical brain surrogate to improve brain …

Addressing The Void Of Ai Policies In Education For Students With Specific Learning Disabilities, Mikyung Shin, Fatmana Deniz, Latesha Watson, Cynthia Dieterich, Kathy B. Ewoldt, Friggita Johnson, Jennifer E. Kong, Sun Hee Lee, April Whitehurst

Faculty Publications - College of Education

The purpose of this study was to identify the current state of artificial intelligence (AI) policies in U.S. education and propose actionable recommendations through large language model–based topic modeling and Delphi surveys. Out of 12 policy documents released between 2015 and 2025, only two documents (National Center for Learning Disabilities, 2024; W.A. v. Clarksville/Montgomery County School System, 2024) specifically addressed learning disabilities. Policy documents addressing topics such as AI-driven risk assessment, data protection, legal risk management, and ethical guidelines covering other disabilities and general AI in education policy were provided as baselines that could be discussed and validated through …

Preservice Teachers’ Perceptions Of Ai- And Human-Generated Feedback On Lesson Plans, Gui Ying Annie Yang-Heim, Xi Lin

Faculty Publications - College of Education

This study examines the role of AI peer reviewers in evaluating preservice teachers’ guided reading lesson plans at a U.S. university. A quasi-experimental design compared two groups: one receiving traditional human peer reviews and another using ChatGPT as a peer reviewer. Data sources included peer review reports and student survey responses. Grounded in the Zone of Proximal Development and effective feedback literature, the study investigates how AI feedback influences critical thinking and engagement during lesson planning. It also explores preservice teachers’ attitudes toward AI versus human feedback. The findings demonstrate both the advantages and disadvantages of AI-generated feedback which provides …

Exploring Asian International Teaching Assistants’ Experiences In The U.S. Tesol Teacher Education: A Raciolinguistic Perspective, Yangyang Zhu, Woongsik Choi, Tirtha Karki

Faculty Publications - College of Education

Asian international teaching assistants (ITAs) in U.S. teacher education experience a range of challenges preparing predominantly white preservice teachers (PSTs). Few studies have examined the teaching experiences of Asian ITAs who also serve as teacher educators in a predominantly white institution (PWI). In this study, we, three Asian ITAs as well as TESOL teacher educators, used collaborative autoethnography to explore our experiences of preparing PSTs to teach multilingual learners at a large public U.S. midwestern PWI. Using raciolinguistic ideologies as the theoretical framework, we analyzed data from our teaching journals, curricular materials, and discussions. We found ourselves feeling frustrated with …

Supporting Teachers’ Learning About Technology Accessibility: A Content Analysis Of Asynchronous Professional Development, Mutiara Syifa, Natalie L. Shaheen

Faculty Publications - College of Education

Accessibility is imperative to providing disabled students a free and appropriate technology-mediated public K-12 education. But according to the literature, teachers often lack the requisite knowledge to ensure the technologies they use are accessible. So, we conducted a study to understand what, if any, asynchronous professional development about technology accessibility was available to teachers and other K-12 professionals. The findings indicate that of the free technology accessibility professional development materials in the sample (a) fewer than 20% are designed for teachers, (b) most provide limited information, and (c) fewer than 9% specifically address science, technology, engineering, and mathematics (STEM) subjects. …

Taking Scale Seriously In Technology Law, Mark P. Mckenna, Woodrow Hartzog

Faculty Scholarship

Issues of scale—the relationship between the amount of an activity and its associated costs and benefits—permeate discussions around law and technologies. Indeed, it’s not much of an exaggeration to say that scale is the reason for most technology regulation.

But it’s not always clear how lawmakers and judges conceptualize “scale” when approaching questions around automated technologies. Scale is often used intuitively, just to mean “more.” But scale is not always just about more—scale can introduce new harms and benefits along different dimensions, not simply costs or efficiencies of greater magnitude.

In this Article, we argue for a more sustained interrogation …

Corporate Law's Duty Of Data Loyalty, Andy Serwin, Neil Richards, Woodrow Hartzog, Ryan Durrie

Faculty Scholarship

Privacy law used to be a relatively tidy field, involving a few interesting but discrete topics like press disclosures of private facts, wiretapping, and the processing of personal data by internet companies. But as the digital revolution continues to disrupt area after area of human activity and software “is eating the world,” the core concerns of privacy law such as “when is it appropriate to process personal data?” have similarly entered field after field. Today, most fields of law, including discrimination law, antitrust, and international law, have found it necessary to reckon with the questions of informational harm and power …

Regulating Crisis Pregnancy Centers After Nifla And Dobbs: Controversies Over When Government Is Imposing An Orthodoxy About Abortion, Linda C. Mcclain

Faculty Scholarship

How does this broader sense of Barnette’s proscription of government from imposing “what shall be orthodox” implicate governmental restrictions on reproductive autonomy? Battles over reproductive freedom centrally implicate objections that government is unconstitutionally imposing a gender orthodoxy. Arguments for a right of personal autonomy embodying an antitotalitarian principle of liberty are arguments for a right to resist governmental imposition of an orthodoxy— for example, an idea about the natural or traditional role of women as mothers together with a view about how best to respect the sanctity of life. Rights to reproductive autonomy, grounded in personal autonomy and equality, …

Resolving Heterogeneity In Lymph Node Stromal Cells Using High-Dimensional Analysis Of Non-Optimized Flow Cytometry Data, Mikala E Heon, Eduardo Rosa-Molinar

2020-Current year OA Pubs

Lymph Node Stromal Cells (LNSCs) are a diverse population of cells responsible for maintaining the lymph node environment and regulating the immune response. Given these roles, they have the potential to help replicate lymph node functions

Rapid Urbanization Reduces Genetic Diversity And Increases Genetic Differentiation Of A Lynx Spider Oxyopes Sertatus In Central Taiwan, Ying-Yuan Lo, Chi Wei, Wan-Jyun Chen, Chung-Ping Lin

Biological Sciences Faculty Publications

Urbanization is a dominant force driving destructive and irreversible changes of natural habitats in modern times. While the effects of urbanization on community composition and phenotypic responses are well-documented, its influence on genetic diversity and population structure remains understudied, particularly for invertebrates in subtropical regions. This study tested the hypothesis that urbanization reduces genetic diversity and increases population differentiation in the lynx spider Oxyopes sertatus, a common foliage-dwelling spider in Taiwan. We sampled 245 individuals from 17 sites distributed along an urban-rural gradient and quantified urbanization intensity using land-use composition at both landscape (4 km²) and local (0.25 km²) …

Overcoming Adaptive Resistance In Non-Small Cell Lung Cancer: Integrating Targeted Therapies, Immunotherapy Synergy, And Nanocarrier Delivery., Luke Ding, Anna Staskiewicz, Jesse Kao, Xinyu Wang

PCOM Scholarly Works

Lung cancer is the leading cause of cancer death, characterized by high mortality rates, tumor adaptation and heterogeneity, and immune evasion mechanisms. Despite recent advancements in chemotherapy, radiation, and surgery, survival rates for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC) remain low, signifying the need for new strategies and innovative treatments. This review explores the combinatorial potential of immunotherapy with direct targeting of tumor growth to address the multifaceted challenges of NSCLC. Key approaches include small-molecule inhibitors, programmed death-ligand 1 (PD-L1) inhibition, angiogenesis inhibition, and nanotechnology-based drug delivery systems. Nanocarrier systems enable coordinated drug release and …

Preclinical Ischemic Stroke Multicenter Trials (Prism) Collective Statement: Opportunities, Challenges, And Recommendations For A New Era, Cenk Ayata, Philip M Bath, Anna M Planas, Stuart M Allan, Johannes Boltze, Claire L Gibson, Marcio A Diniz, Stefano Fumagalli, Fahmeed Hyder, Raymond C Koehler, Arthur Liesz, Sarah K Mccann, Tim Magnus, Louise D Mccullough, Emily S Sena, Simone Beretta, Jaroslaw Aronowski, Francesca Bosetti, Clinton B Wright, Patrick D Lyden, Lauren H Sansing

Faculty, Staff and Student Publications

Preclinical stroke research faces a critical translational gap, with animal studies failing to reliably predict clinical efficacy. To address this, the field is moving toward rigorous, multicenter preclinical randomized controlled trials (mpRCTs) that mimic phase 3 clinical trials in several key components. This collective statement, derived from experts involved in mpRCTs, outlines considerations for designing and executing such trials. mpRCTs offer advantages such as increased sample sizes, robust statistical design, incorporation of heterogeneity, and standardized protocols, but they face challenges in finding the right balance between standardization and heterogeneity, appropriate stroke model selection, and outcome measures, as well as the …

Engineering Mutation Clones In Mammalian Cells With Crispr/Cas9, Zijun Huo, Jian Tu, Rachel Shoemaker, Dung-Fang Lee, Ruiying Zhao

Faculty, Staff and Student Publications

CRISPR, Clustered Regularly Interspaced Short Palindromic Repeat, as a powerful genome engineering system, has been widely accepted and employed in gene editing of a vast range of cell types. Compared to zinc finger nucleases (ZFNs) or transcription activator-like effector nucleases (TALENs), CRISPR shows a less complicated process and higher efficiency. With the development of different CRISPR systems, it can be used not only to knock out a gene but also to make precise modifications, activate or repress target genes with epigenetic modifications, and even for genome wide screening. Here we will describe the procedure of generating a stable cell line …

Uncertainty-Guided Test-Time Optimization For Personalizing Segmentation Models In Longitudinal Medical Imaging, Jaehee Chun, Austin Castelo, Mckell Woodland, Caleb O'Connor, Mais Al Taie, Aashish Gupta, Shanli Ding, Jeddy Bennett, Anirban Maitra, Matthew A Firpo, Kimberly Kirkwood, Eugene J Koay, Kristy K Brock

Faculty, Staff and Student Publications

Background: Accurate and consistent image segmentation across longitudinal scans is essential in many clinical applications, including surveillance, treatment monitoring, and adaptive interventions. While personalized model adaptation using patient-specific prior scans has shown promise, current approaches typically rely on fixed training durations and lack mechanisms to determine optimal stopping points on a per-patient basis, particularly in the absence of validation labels.

Purpose: We propose an uncertainty-guided test-time optimization (TTO) framework that dynamically adjusts the personalization duration for each patient using a validation-free stopping criterion based on predictive uncertainty.

Methods: Our framework personalizes a generalized segmentation model using patient-specific prior imaging and …

Digital Communication Strategies For Culinary Medicine In Cancer Prevention And Survivorship: Information-Seeking Habits And Content Preferences Of Online Cooking Media Among Adults Participating In Four Cancer Prevention And Control Cohort Studies, Margaret Raber, Sara Fares, Maria Vazquez, Larkin Strong, Carrie Daniel-Macdougall, Karen Basen-Engquist

Faculty, Staff and Student Publications

Introduction

Poor diet and excess weight have been linked to increased risk for at least 13 types of cancer. Culinary medicine utilizes experiential cooking skill development to improve individuals’ capacity for healthy eating. Digital communication strategies offer pathways for scalable culinary medicine interventions, but little research has explored how online cooking tools could be leveraged for cancer prevention messaging. We conducted a cross-sectional survey study exploring online cooking information-seeking habits and content preferences among participants in four cancer prevention and control cohorts to inform future digital culinary medicine interventions.

Methods

A cross-sectional survey study was conducted with a convenience sample …

Nsd2 Inhibitors Rewire Chromatin To Treat Lung And Pancreatic Cancers, Jinho Jeong, Simone Hausmann, Hanyang Dong, Kacper Szczepski, Natasha M Flores, Liyang Shi, Joanna Lempiäinen, Moritz Jakab, Liyong Zeng, Tourkian Chasan, Eric Bareke, Rui Dong, Emma Carlson, Reinnier Padilla, Dylan Husmann, Julia Thompson, Gerry A Shipman, Emily Zahn, Courtney A Barnes, Laiba F Khan, Liz Marie Albertorio-Sáez, Eva Brill, Vishnu Udayakumar Sunita Kumary, Matthew R Marunde, Danielle N Maryanski, Cheryl C Szany, Bryan J Venters, Carolina Lin Windham, Michal Eligiusz Nowakowski, Iwona Czaban, Mariusz Jaremko, Michael-Christopher Keogh, Kang Le, Michael J Soth, Benjamin A Garcia, Łukasz Jaremko, Jacek Majewski, Pawel K Mazur, Or Gozani

Faculty, Staff and Student Publications

NSD2 catalyses the epigenetic modification H3K36me2 (refs. 1,2) and is a candidate convergent downstream effector of oncogenic signalling in diverse malignancies3–5. However, it remains unclear whether the enzymatic activity of NSD2 is therapeutically targetable. Here we characterize a series of clinical-grade small-molecule catalytic NSD2 inhibitors (NSD2i) and show that the pharmacological targeting of NSD2 constitutes an epigenetic dependency with broad therapeutic efficacy in KRAS-driven preclinical cancer models. NSD2i inhibits NSD2 with single-digit nanomolar half-maximal inhibitory concentration potency and high selectivity over related methyltransferases. Structural analyses reveal that the specificity of NSD2i for NSD2 …

Applications And Challenges Of Utilizing Digital Pathology And Ai-Enabled Workflows In Clinical Trials, Manu Sebastian, Harsh Batra, Monika Lamba Saini, Staci Kearney, Lorcan Sherry, Michael Cohen, Joe Lennerz, Anil V Parwani

Faculty, Staff and Student Publications

This is a comprehensive review on current utilization and challenges of digital pathology adoption in clinical trials and aims to provide a broad view on its impact on pathology review processes in clinical trials. It provides an overview of current pathology review practices in clinical trials and unique advantages digital pathology adoption can offer. The key areas including existing workflows, use case scenarios in different disease areas in clinical trials, including but not limited to patient identification and pre-screening, and regulatory aspects have been described with relevance. In addition, the review delves into the integration of genomics, AI, image analysis, …

Enhancing Inter-Institutional Ai Research Collaboration Across Multidisciplinary Teams To Increase The National Ai Workforce In Healthcare, Zulfiia Ditto, Paul Warhurst, Jay Johnson, Jamboor K Vishwanatha

Faculty, Staff and Student Publications

Inter-institutional team collaboration is critical for impactful multidisciplinary AI research in healthcare. The goal of our project (AIM-AHEAD Connect) is to increase multidisciplinary collaborations by connecting AI/ML experts and healthcare researchers, trainees and professionals to enhance research and improve health for all Americans. As of February 2026, AIM-AHEAD Connect has over 10,100 AI/ML and healthcare experts from across 2,400 institutions, has made more than 7,800 connections and facilitated 194 collaborative online groups. We conducted a unique study to understand collaboration, and analyzed profile, connection, and platform engagement metrics to determine if AI experts and healthcare researchers with more inter-institutional connections …

Ideational Behavior And Occupational Identity Achievement: A Study Of Emerging Adult College Students Preceding Entry Into The Fouth Industrial Revolution Workforce, Carrington M. Faulk, Michael F. Kosloski, Philip Reed

Marketing Faculty Publications

As emerging adults transition into the Fourth Industrial Revolution (4IR) workforce, it is essential to understand the factors that predict successful occupational identity achievement, as automation will impact human occupational identity crises. This descriptive cross-sectional study employed a correlational design to determine the degree to which ideational behavior predicts occupational identity achievement prior to entry into the 4IR workforce. Using a sample of 166 emerging adult college students from a Mid-Atlantic, diverse, four-year university, data were collected using Runco's Ideational Behavior Scale (RIBS) and Melgosa's Occupational Identity Achievement subscale (OIA). Results showed that ideational behavior significantly predicted occupational identity achievement …

Artificial Intelligence And Consumer Well-Being: A Cross Domain Systemic Review, Setar Lytle, Mahesh Gopinath

Marketing Faculty Publications

Artificial intelligence (AI) is increasingly embedded in everyday consumption, yet evidence on its longer-term implications for consumer eudaimonic well-being remains dispersed across disciplines and application contexts. This review integrates that literature to clarify the domains, theoretical explanations, and conditions through which AI shapes consumer well-being. Following PRISMA and SPAR-4-SLR procedures, we reviewed research published from January 2010 to January 2026. From 6058 records, 480 studies across psychology, business, and human-technology interaction met the inclusion criteria. The evidence is organised through psychological, social, and technological perspectives and identifies six interconnected domains: mental health, cognitive development, physical health, personal growth, autonomy and …

Single-Cell Lineage Trajectory Defines Cyclin-Dependent Kinase Inhibitor-Sensitive Cells-Of-Origin In Esophageal Squamous Cell Carcinoma, Kyung-Pil Ko, Jie Zhang, Sohee Jun, Jae-Il Park

Faculty, Staff and Student Publications

Background and aims: Understanding the cells of origin is essential for overcoming therapy resistance and improving early intervention strategies in esophageal squamous cell carcinoma (ESCC). Despite recent advances in genomic profiling, the precise cellular hierarchies and molecular programs driving ESCC initiation remain poorly defined.

Methods: We utilized machine learning-based single-cell trajectory analysis on 4-nitroquinoline 1-oxide-induced murine models and genetically engineered organoids to identify cellular lineages during tumorigenesis. Combined with gene regulatory network analysis, we identified transcriptional drivers of tumor initiation and employed transcriptome-based drug repurposing to predict compounds targeting these initiating populations.

Results: Our analyses revealed multiple distinct epithelial clusters …

Prickle4 Drives Microenvironmental Remodeling And Resistance To Parp Inhibition In Idh-Mutant Glioma, Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yinghong Xiong, Kexin Ling, Ying Liu, Jason T Huse, Bo Chen, Timothy A Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang

Faculty, Staff and Student Publications

Mutations in isocitrate dehydrogenase (IDH) genes sensitize gliomas to PARP inhibition (PARPi) by inducing epigenetic reprogramming of DNA damage repair circuits. However, tumors treated with PARPi eventually relapse despite initial responsiveness. In this study, it is demonstrated that the anti-angiogenic agent lenvatinib synergizes effectively with PARPi, resulting in substantial tumor regression and significantly extended survival. Genomic analysis of tumors reveals that PARPi induces widespread transcriptomic changes that are predominantly pro-inflammatory, thereby promoting tumor angiogenesis. Prickle4, a planar cell polarity protein, is identified as a critical mediator of PARPi-induced neovascularization. Targeting Prickle4 effectively overcomes PARPi resistance in these tumors. Collectively, these …

Host Modulation Therapy In Periodontitis: From Established Therapies To Emerging Technologies, Aonjittra Phanrungsuwan, Jiaqi Huang, Neeraja Dharmaraj, Alejandra Cobos Perez, Omid Veiseh, Chun-Teh Lee

Faculty, Staff and Student Publications

Periodontitis is a biofilm-induced chronic inflammatory disease, characterized by gingival inflammation and alveolar bone loss. According to a national survey, approximately half of the U.S. adults are affected by periodontal disease. To effectively prevent and treat periodontitis, it is essential to address its underlying causes. The primary etiological factors include polymicrobial synergy and dysbiosis of the oral microbiota, and a dysregulated immune response. The standard therapeutic approach, mechanical removal of biofilm through debridement, sometimes demonstrates limited efficacy, particularly in cases of severe periodontitis, which may require adjunctive or additional therapy. Emerging evidence indicates that periodontal tissue destruction is initiated by …