Drug Therapy Of Anxiety Disorders And Depression: Considerations For Dental Treatment, David Tindle Dds, Ms

The Journal of the Michigan Dental Association

This clinical article examines the dental implications for patients taking psychiatric medications. It reviews major drug classes, including SSRIs, SNRIs, and benzodiazepines, focusing on oral side effects like xerostomia and bruxism. The author details critical drug interactions with local anesthetic vasoconstrictors and macrolide antibiotics. Crucially, the source explores research suggesting that SSRIs may significantly increase the risk of dental implant failure by interfering with bone metabolism and osseointegration.

2026 May, Morehead State University. Office Of Communications & Marketing.

Morehead State Press Release Archive, 1961 to the Present

Press releases for May of 2026.

Resilience, Stress, And Emotion Regulation In College Students: A Moderated Mediation Model Of Tiktok Engagement, Samuel Bibat, Jon Thang, Hui Zhang, Hannah Carrie, Jessica Golden

Journal of Social, Behavioral, and Health Sciences

This study examined associations between stress, resilience, emotion regulation (ER), and TikTok use. Data were collected from 101 undergraduate students (M_age = 20.04, SD_age = 4.02) at a Midwestern private university. Participants completed self-report measures of TikTok use and intensity (i.e., emotional attachment), resilience, perceived stress, and intrapersonal and interpersonal ER. Mediation and moderated mediation analyses were conducted using PROCESS macro models. Stress mediated the relationship between resilience and TikTok use but not intensity. Interpersonal ER moderated the resilience–stress link, with higher interpersonal ER amplifying the negative association between resilience and stress, which in turn was linked …

Analysis Of Volumetric Reconstruction Methods In Archaeology, Cade O'Fallon

All-Inclusive List of Electronic Theses and Dissertations

The use of Structure from Motion (SfM) photogrammetry in archaeological projects is entering a period of transition; a method of producing 3D data that is traditionally embraced as tool for documentation is being explored for its analytic potential. One such way SfM photogrammetry can be used analytically is through the calculation of volumes using photogrammetric data. The tools exist for archaeologists to be able to create and quantify volumetric models; however, the discourse on these methods is still so new there is no consensus on the best method for conducting volumetric work. Different methods of creating and isolating volumetric space …

Microplastic Composition And Exposure Pathways In Freshwater Systems: A Multi-Matrix Comparison Between Streams And Retention Ponds In Hamilton County, In, Mya Whaley

All-Inclusive List of Electronic Theses and Dissertations

Since the early 1900s, the use of plastics has increased exponentially. The breakdown of plastic materials has exposed all ecosystems to microplastics (small particles of plastic < 5 mm), which are now ubiquitous in natural settings. Microplastics have a relatively large surface area, and many chemicals adsorb to these small particles, impacting their fate and transport of pollution. While microplastics have been found in virtually every setting on Earth, research is necessary to understand their impact on freshwater ecosystems and biogeochemical cycles. The focus of this research was to investigate microplastic compositions in crayfish, sediments, and water samples collected in streams and retention ponds. We analyzed trends in microplastic counts across different land-cover classes, waterbody types, and species, and compared concentrations among matrices to improve our understanding of microplastic exposure pathways in freshwater ecosystems. As a secondary objective, lead and arsenic concentrations were analyzed from sediment samples to investigate metal burdens and compare them to microplastic concentrations. Our findings revealed that, in general, urban streams had the highest microplastic concentrations within land cover categories, and retention ponds had higher microplastic counts than streams. Crayfish, such as F. rusticus had higher microplastic concentrations than F. virilis and F. propinquus, although these results may be influenced by study design. The most common microplastic type was fibers, and most common color was transparent. There was no significant correlation between microplastic and metal concentrations in sediments. We found crayfish to be adequate bioindicators of microplastic pollution, because they were less impacted by environmental variability than sediment and water samples. This research presents the first evidence of microplastics in our study species, F. propinquus, F. rusticus, and F. virlis. This work presents new evidence of microplastic accumulation in crayfish, sediments, and water from freshwater systems in the Midwestern United States. Microplastics were found in every sample type—crayfish, water, and sediment—across urban, rural, and forested landscapes, highlighting their pervasive distribution. The findings provide foundational data for assessing emerging ecological and human-health risks and emphasize the importance of sustained monitoring and research on MP contamination in freshwater environments.

Personality Characteristics Of Emergency Nurses And Their Subjective Fit In The Emergency Department, Jose Michael Maria

Theses & Dissertations

Nursing workforce challenges in the United States persist despite widespread recruitment and retention efforts, and the COVID-19 pandemic has further exacerbated shortages, turnover, and workforce instability. Despite interventions such as residency programs, financial incentives, and organizational initiatives, long-term retention remains inconsistent, particularly in high-demand settings like emergency departments. Ongoing issues such as overcrowding, rising patient acuity, and workforce attrition contribute to burnout, compassion fatigue, and compromised patient outcomes, perpetuating a cycle of staffing strain. Grounded in Person–Environment Fit theory, this research proposes that aligning emergency nurses’ personality traits with the specialty practice environment, the emergency department, may offer a more …

Caring For Transgender People In Healthcare: A Qualitative Descriptive Study With Nurses Working In An Acute Healthcare Setting, Gabriela Roxana Matson

Theses & Dissertations

Transgender individuals frequently encounter numerous obstacles when accessing healthcare services, including stigma, discrimination, and inadequate understanding from healthcare providers. Structural, interpersonal, and anticipation barriers significantly hinder transgender patients' access to care. Structural barriers include a lack of healthcare providers knowledgeable in transgender health and financial constraints. Interpersonal barriers involve discrimination, such as refusal to use correct pronouns or provide gender-affirming care. Anticipation barriers stem from fear of mistreatment, causing many to avoid seeking medical care altogether. Nurses play a vital role in upholding inclusive and affirming healthcare This qualitative descriptive study explored the subjective experiences of registered nurses who provided …

Research "Junkification" Is Caused By Researchers, Not Journals, Simon Sebastian Groome, Jose C. Yong, Norman P. Li

Research Collection School of Social Sciences

Concerns about declining research quality have increasingly been framed as “junkification,” whereby academic output expands in volume while declining in epistemic value. A recent paper by Rhodes and Linnenluecke (2025) attributes this trend to changes in publishing, arguing that research quality erodes as journals and publishers become increasingly oriented toward output quantity and metrics, driven by monetization. In 2009, Nobel Laureate James Watson remarked that scientific publishing in the mid-twentieth century was both easier and of a higher standard than today (Web of Stories, 2017). If publishing is much easier of late, as Rhodes and Linnenelucke (R&L) argued, then how …

Adolescent Social Media Use And Associations With Parental Screen Time Practices, Joseph A. Simon, Josiah Leong

Biological Sciences Undergraduate Honors Theses

The rise of electronic use among younger generations has raised concerns surrounding  the developmental and behavioral effects of increasing usage. While past research has found some associations between screen time and mental health, there is less knowledge about how parenting practices influence these developmental and behavioral patterns of social media use. Our study examined longitudinal trajectories of social media use from ages 9 to 13 among 9,211 subjects at baseline, year 1, year 2 and later a complete 3-year parent questionnaire on screen time reward, limiting, and monitoring to then examine whether parenting behaviors were associated with previous social media …

Growth Hormone Pathway As A Prognostic And Therapeutic Biomarker In Patients With Unresectable Hepatocellular Carcinoma Treated With Radiation Therapy, Joe R Eid, Safa Kaseb, Lianchun Xiao, Ryan Sun, Mahesh Kumar Kannan, Manal Hassan, Asif Rashid, Hop S Tran Cao, Hesham M Amin, Eugene J Koay

Faculty, Staff and Student Publications

Purpose: Radiation therapy (RT) has emerged as an effective local therapy option for patients with unresectable hepatocellular carcinoma (HCC) and is associated with improved overall survival (OS). However, some patients still have poor outcomes after RT, and biomarkers are needed to stratify prognostic groups. High circulating growth hormone (GH) levels promote HCC proliferation and survival and are associated with aggressive disease. In this study, we evaluated whether pretreatment GH levels are associated with OS and progression-free survival (PFS) in patients who underwent RT for unresectable HCC.

Methods and materials: Patients undergoing RT for HCC during 2017-2023 were identified from a …

Examining Pathogenic Vibrio Abundance And Environmental Controls Across Macroalgae, Sediment, And Oysters, Alexandra H. Geisser, Abigail K. Scro, Roxanna Smolowitz, Robinson W. Fulweiler

Arts & Sciences Faculty Publications

Climate change is accelerating the geographic spread and abundance of pathogenic Vibrio species in coastal waters, posing growing threats to ecosystems and human health. We investigated the abundance and pathogenic gene presence of V. vulnificus and V. parahaemolyticus across three common estuarine substrates (macroalgae, sediment, and oysters) in a temperate estuary. Macroalgae consistently harbored the highest Vibrio counts in conjunction with elevated pathogenic gene frequencies, while oysters contained the lowest. Environmental conditions related to Vibrio abundance were substrate and Vibrio species specific. Temperature and salinity were most closely related to pathogenic Vibrio abundance in oysters. In contrast, pathogenic Vibrio abundance …

Biohybrid Robotic Jellyfish For Swimming-Enhanced Vertical Ocean Profiling, Kelsi M. Rutledge, Sean Colin, John H. Costello, Noa Yoder, Simon R. Anuszczyk, Kelly R. Sutherland, Brad L. Gemmell, John O. Dabiri

Arts & Sciences Faculty Publications

Ocean monitoring is essential for understanding climate change and marine ecosystem dynamics, yet achieving comprehensive global coverage remains a challenge in oceanography. Current technologies face limitations in cost, power, hardware, and depth capacity that restrict widespread monitoring capabilities. Here we show that biohybrid robotic jellyfish (Aurelia aurita) can serve as autonomous vertical ocean profilers by integrating microcontrollers with positively buoyant sensor payloads, achieving controlled vertical-profiling capabilities. Laboratory experiments demonstrated repeatable up–down trajectories, quantified force balance limits, and identified predictable, size-dependent descent swimming speeds. Field deployments in Massachusetts coastal waters and the open ocean off the Florida Keys demonstrated field operation …

Enhancing Traffic Safety Through Ai-Driven, Privacy-Preserving, And Secure Impaired Driving Detection Systems, Razan Alsulieman

Dissertations

Drunk driving remains a major threat to road safety worldwide, contributing significantly to traffic injuries and fatalities each year. Traditional detection approaches are largely reactive and vehicle-centric, relying on in-vehicle sensors, breathalyzers, or post-incident enforcement. These methods often depend on driver cooperation, intrusive hardware installations, or limited monitoring environments, restricting their scalability and effectiveness in large transportation systems. At the same time, modern cities increasingly deploy roadside cameras, surveillance networks, and drone- based monitoring systems, creating new opportunities for proactive intoxication detection at the infrastructure level. However, leveraging such external monitoring introduces challenges related to secure data collection, reliable AI-based …

Full Issue

The Bridge

No abstract provided.

Unravelling Taxonomic Complexity In Elusive Cetaceans: Mitogenome Insights Into Evolutionary History And Cryptic Diversity Of Bryde's Whales, Dominique Paynee, Paulette Bloomer, Gwenith Penry, Simon Elwen, Ada Natoli, Vaisakh Dhanalakshmy, Thyago Cardoso, Els Vermeulen

All Works

Cetaceans, despite their ability to cross wide distances, enabling mostly high levels of gene flow, can develop unique genetic lineages driven by variations in life-history traits, diverse migratory routes and local adaptation, complicating taxonomy and delineation of conservation units. Comprehensive genetic data are essential to overcome the challenges of obtaining suitable sample sizes from wild cetaceans while untangling cryptic species diversity. The Bryde's whale (Balaenoptera edeni) has a complicated discovery and taxonomic history that hinders accurate conservation assessments. In southern Africa, two populations are recognised: the inshore (SAi) and the offshore southeast Atlantic population (SEA). This study examines their phylogenetic …

Plasma Proteins Associated With Psychosocial Factors And Heart Disease: The Jackson Heart Study, Sara N O'Brien, Madeline G Gillman, Michael D Green, Daniel E Cruz, James S Floyd, Susan Hankinson, Daniel H Katz, Xiaojuan Liu, Michelle C Odden, Bruce M Psaty, Alexander P Reiner, Jerome I Rotter, Stephen S Rich, Robert E Gerszten, Amil Shah, Mario Sims, Usman A Tahir, Lesley F Tinker, Alexis C Wood, Bing Yu, Anthony S Zannas, Laura M Raffield, Láshauntá M Glover

Faculty, Staff and Students Publications

Background: Knowledge of proteomic mechanisms explaining the link between psychosocial stress and cardiovascular disease is limited. This study aimed to (1) identify plasma proteins associated with psychosocial factors and (2) assess associational pathways between psychosocial factors, identified proteins, and incident cardiovascular disease events in a discovery cohort, JHS (Jackson Heart Study), and 2 replication cohorts, the CHS (Cardiovascular Health Study), and the MESA (Multi-Ethnic Study of Atherosclerosis).

Methods: JHS participants from exam 1 (2000-2004) with SomaScan 1.3k platform proteomics data were included (n=2143, mean age=55.3). Depressive symptoms and perceived stress scores were measured via the 20-item Center for Epidemiological Studies …

Fructose: Metabolic Signal And Modern Hazard, Richard J Johnson, Miguel A Lanaspa, Dean R Tolan, Marcus D Goncalves, Samir Softic, Kimber L Stanhope, Laura G Sánchez-Lozada, Mark A Herman, Joshua D Rabinowitz

Faculty, Staff and Students Publications

There is much interest in the role of sweeteners such as table sugar (sucrose) and high-fructose corn syrup in obesity and metabolic disease. Both sweeteners consist of glucose and fructose, two six-carbon isomeric sugars. Whereas glucose ingestion may promote obesity through its effects to stimulate insulin secretion, fructose has unique metabolic effects that promote triglyceride synthesis and fat accumulation. These effects arise from fructose's well-known role as a signal of metabolic plenty. Under modern conditions of overnutrition, chronic excess fructose drives features of metabolic syndrome. Emerging evidence further links fructose to cancer and dementia. Here we review the biochemical, molecular …

Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz

Faculty, Staff and Students Publications

Adhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium to publish a comprehensive review about aGPCRs and establish a unified nomenclature. Since then, substantial progress has been made in delineating the biological roles, molecular architecture, biochemical properties, expression profiles, ligand repertoire, and activation and signaling strategies of aGPCRs. Commensurate with these advances, their relevance to human pathophysiology has become increasingly apparent. In a coordinated effort, the Adhesion GPCR Consortium has reviewed recent progress in this field and provides a comprehensive …

Adhesion G Protein-Coupled Receptors, Tobias Langenhan, Garret R Anderson, Demet Araç, Gabriela Aust, Monserrat Avila-Zozaya, Sofie Morsing Bagger, Patrick Barth, Sandra Berndt, Stephen C Blacklow, Beatriz Blanco-Redondo, Antony A Boucard, James P Bridges, Lara-Sophie Brodmerkel, Kathleen M Caron, Yin Kwan Chung, Andrew N Dates, Virginea De Araujo Farias, Daniel Del Toro, Joseph G Duman, Felix B Engel, David M Favara, Caroline J Formstone, Chaoyu Fu, Alain Garcia De Las Bayonas, Anastasia Georgiadi, David E Gloriam, Randy A Hall, Jörg Hamann, Peter W Hildebrand, Cheng-Chih Hsiao, Bill X Huang, Jonathan A Javitch, Hee-Yong Kim, Robert J Kittel, Gunnar Kleinau, Richard Leduc, Ines Liebscher, Hsi-Hsien Lin, Joshua Linnert, Marie-Gabrielle Ludwig, David C Martinelli, Signe Mathiasen, Daniel Matúš, Mariam Melkumyan, Ana L Moreno-Salinas, Jan Mulder, Michael A Nash, Kasturi Pal, Daniel T Pederick, Nicole A Perry-Hauser, Xianhua Piao, Yu-Qi Ping, Dimitris G Placantonakis, Fabian Pohl, Simone Prömel, Mette M Rosenkilde, Laurent Sabbagh, Richard C Sando, Patrick Scheerer, Torsten Schöneberg, Elena Seiradake, Mareike Selcho, Florian Seufert, Abhishek K Singh, Georgios Skiniotis, Katja Spiess, Norbert Sträter, David Strutt, Thomas C Südhof, Jinpeng Sun, Gregory G Tall, Doreen Thor, Douglas G Tilley, Kimberley F Tolias, Mario Vallon, Erwin G Van Meir, Benoit Vanhollebeke, Giselle R Wiggin, Uwe Wolfrum, Jie Yan, Nathan A Zaidman, Yimin Zou, Nicole Scholz

Faculty, Staff and Students Publications

Adhesion G protein-coupled receptors (aGPCRs) constitute a structurally and functionally distinct group within the superfamily of GPCRs. In 2015, the International Union of Pharmacology invited the Adhesion GPCR Consortium to publish a comprehensive review about aGPCRs and establish a unified nomenclature. Since then, substantial progress has been made in delineating the biological roles, molecular architecture, biochemical properties, expression profiles, ligand repertoire, and activation and signaling strategies of aGPCRs. Commensurate with these advances, their relevance to human pathophysiology has become increasingly apparent. In a coordinated effort, the Adhesion GPCR Consortium has reviewed recent progress in this field and provides a comprehensive …

Vitaltitration Predicts Fermentation Performance Of Phylogenetically Distinct Saccharomyces Cerevisiae Yeast Strains, Samantha White Ms

All Student Scholarship

Accurate assessment of yeast physiological health is essential for achieving consistent, efficient, and predictable beer fermentations. Although yeast vitality is more predictive of fermentation performance than viability alone, no universally adopted vitality assay currently exists in the brewing industry. This thesis investigates vitaltitration (VT) as a rapid, robust, and brewery-feasible method for quantifying yeast vitality and predicting fermentation performance. We hypothesize that VT provides a reliable measure of metabolic competence that correlates with fermentation kinetics across brewery-relevant yeast strains. To test this hypothesis, VT was evaluated alongside Acidification Power (AP) in structured serial-fermentation experiments in two phylogenetically distinct brewing yeasts: …

Does Self-Compassion Buffer Against The Potential Effects Of Perfectionism And Psychopathology On Non-Suicidal Self-Injury?, Natasha Bourgoin

Electronic Theses and Dissertations

University students with increased rates of reported perfectionism, anxiety, and depression, are vulnerable to non-suicidal self-injury (NSSI). However, not all students with psychological distress engage in NSSI, suggesting protective factors may help to mitigate this risk. The present study examined the relation between perfectionism and NSSI, via the mediating effects of anxiety and depression, and the moderating role of self-compassion. Participants were 338 university students (67% female; 87% White) who completed several self-report measures. Students with greater perfectionism reported higher levels of anxiety and depressive symptoms and, in turn, more NSSI engagement. Self-compassion and several self-compassionate domains attenuated connections between …

Stability Of Paraffin-Insulated Nitrogen-Doped Carbon Fiber Ultramicroelectrodes, Maxwell H. Kwakwah

Electronic Theses and Dissertations

Nitrogen-doped carbon materials can facilitate the reduction oxygen-oxygen bonds, a key step in electroreduction of both O₂ (an important reaction in energy applications) and H₂O₂ (an important reaction in sensing and biosensing). Our lab previously demonstrated that thermal decomposition of urea in the presence of carbon fiber (CF) results in an N-doped carbon material that exhibits good electrocatalytic properties for H₂O₂ reduction. However, previous methods of insulating single N-doped CF via laser heating of borosilicate capillaries and epoxy to prepare ultramicroelectrodes (UMEs) seemed to adversely affect surface nitrogen contents and electrocatalytic properties. More recent work that utilized paraffin to …

Media Portrayal Of High-Profile Female Victims Of Sexual Harassment, Chinenye Nwaneri

Electronic Theses and Dissertations

This rhetorical study investigated how the Nigerian media portray high-profile female victims of sexual harassment. The research was undertaken in response to concerns that media narratives often reinforce gender stereotypes and influence public perceptions of victims. Focusing on the sexual harassment allegations made by senator Natasha Akpoti-Uduaghan against Senate president Godswill Akpabio, the study analyzed newspaper coverage from Daily Trust and Vanguard between February and December 2025. Using Critical Discourse Analysis within the framework of Feminist Media Theory, the research examined how language and framing shaped the representation of the female accuser. The findings reveal that media coverage constructed the …

Post-Exercise Vitals Recovery Response In Barrel Horses: A Field Study On Cooling Methods Used By Competitors, Lauran E. Hetrick

Electronic Theses and Dissertations

Barrel racing demands peak physical performance from equine athletes, yet limited research evaluates the field-based strategies used to optimize equine recovery at competition. This study assessed recovery management approaches used by competitors to elucidate their influence of physiological recovery by measuring heart rate, respiratory rate, and body temperature during a high-profile barrel race competition. Physiological data were collected at baseline, immediately post-exercise, and during a 15–30-minute cooldown period to characterize recovery under real-world conditions. Significant increases in HR, RR, and BT occurred from baseline to post-run (p < 0.001), followed by reductions during cooldown (p < 0.01), though values remained elevated (p < 0.05). Rinsing reduced HR and RR (p < 0.01), while shade and fans decreased RR and variably influenced HR. Noise, as a confounding variable, decreased HR but increased BT (p < 0.001). Ultimately, these results emphasize multimodal recovery approaches in competitive equine management in the field.

Propagation And Cultivation Of Sarracenia Species, Kathryn M. Huether

Electronic Theses and Dissertations

This study evaluates the effectiveness of seed treatments on Sarracenina species to overcome seed dormancy; as well as evaluating fertilizer concentration and substrate mixture impacts on the growth of Sarracenia × wrigleyana, ‘Scarlet Belle’. The first portion of this study evaluated the effects of cold stratification and chemical treatments (smoke water and gibberellic acid) on the germination rates of Sarracenia alata and leucophylla. The primary objective was to determine whether increasing concentrations of these treatments paired with or without stratification could significantly enhance germination and serve as viable seed treatments for horticultural use. Germination did occur within all the …

Body Size Variation And Floral Associations Of The American Bumble Bee, Bombus Pensylvanicus, In East Texas, Sabekun Nahar

Electronic Theses and Dissertations

The American bumble bee, Bombus pensylvanicus, is an important pollinator species that was once widespread in much of North America but has experienced population declines in recent decades in some regions. As a species of conservation concern, it is important to understand how body size varies in response to environmental conditions and to identify the key floral resources that support this species. I examined body size variation in East Texas and floral resource use of B. pensylvanicus across Texas. In the first chapter, body size variation among queens, workers, and males was quantified using thorax width and size variation …

Integrated Geophysical, Geotechnical, And Mineralogical Characterization Of Expansive Weches Formation Soils In East Texas: Implications For Infrastructure Design, Samuel Annobil

Electronic Theses and Dissertations

This study investigates the geotechnical, geophysical, and mineralogical characteristics of soils derived from the Weches Formation in Nacogdoches County, East Texas, with emphasis on the relationships among electrical resistivity, moisture condition, compaction state, and mineralogical composition. The Weches Formation is well known for producing clay-rich, moisture-sensitive soils that pose challenges to subgrade performance because of their plasticity and swelling behavior. Representative soil samples were collected and subjected to laboratory testing, including particle size analysis, Atterberg limits, Standard Proctor compaction, free swell tests, electrical resistivity measurements, and X-ray diffraction (XRD) mineralogical analysis. The soils are predominantly fine-grained and clay-rich, with USCS …

Predictors Of Elevated Borderline Personality Disorder And Pai-Bor Scores: The Role Of Psychological, Trauma, And Treatment Factors, Isabel Avendano Gil

Electronic Theses and Dissertations

Borderline Personality Disorder (BPD) is a complex and multifaceted mental health condition that significantly affects individuals' emotional, cognitive, and interpersonal functioning. BPD is characterized by impulsivity, emotional dysregulation, unstable relationships, and self-destructive behaviors, and often results in significant impairment across multiple life domains. Previous research has consistently identified Adverse Childhood Experiences (ACEs), particularly sexual abuse (SA), as key contributors to the development of BPD. These early traumas are closely associated with core features of the disorder, including affective instability, identity disturbance, impulsivity, and maladaptive interpersonal patterns.

Psychotherapeutic interventions, such as Dialectical Behavior Therapy (DBT) and Cognitive Behavioral Therapy (CBT), have …

Reward Representation Learning, Gregory M. Hyde

Dartmouth College Ph.D Dissertations

The \emph{Markov decision process} (MDP) has long served as the canonical model for sequential decision-making. However, it assumes that the reward function is Markov with respect to a given state representation---an assumption that often does not hold in practice. Instead, agents typically only perceive streams of observations and actions and must infer the latent structure according to which reward unfolds over time. From this perspective, reward prediction is initially non-Markov, reflecting a mismatch between the agent's current representation and the underlying structure of the environment.

In this thesis, we advance the view that reward is not simply a signal to …

Data-Driven Multimodal Mri Representation Learning For Subtype Discovery And Disease Progression Modeling In Parkinson’S Disease, Zihan Zhou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Parkinson’s disease (PD) exhibits substantial clinical and neuroanatomical heterogeneity, limiting robust patient stratification and clinically meaningful progression modeling from MRI. We propose a unified multimodal 3D generative representation-learning framework that learns an interpretable latent space from co-registered baseline T1/T2 MRI with an edge-aware channel. Confound-corrected latent embeddings support unsupervised subtype discovery, while disease duration provides weak supervision to orient a continuous progression axis. On an independent external cohort (PPMI, N=171), the discovery-trained subtype structure shows significant partial replication (ARI=0.35; permutation test p=0.001) and enables longitudinal clinical stratification: mixed-effects modeling reveals subtype-dependent MDS-UPDRS III progression, with the strongest effect in subtype …