Digital Commons Network^™

Current Status Of Anthelmintic Resistance In Meat Goats: A Comparative Efficacy Study Of Albendazole And Fenbendazole In Maha Sarakham, Thailand, Minta Pipatsakulpak, Usanisa Boonum, Kotchakorn Roongruang, Benjawan Sae-Chue, Sukanya Leethongdee, Songsak Chumpawadee, Nattaya Watwiengkam, Pongphol Pongthaisong

The Thai Journal of Veterinary Medicine

Anthelmintic resistance in gastrointestinal nematodes threatens sustainable goat production globally. While resistance is well-documented in many regions, data from Thailand remain limited. This study determined the prevalence of gastrointestinal nematodes and assessed the efficacy of albendazole and fenbendazole in meat goats in Maha Sarakham province, northeastern Thailand. A two-stage cross-sectional study was conducted on 10 meat goat farms between August 2021 and March 2022. In Stage 1, fecal samples from 150 goats were examined using simple flotation and sedimentation techniques to identify parasite morphology. In Stage 2, the McMaster technique was employed to quantify fecal egg counts (FEC). Twenty-six goats …

Exploring The Halal Perspectives On Animal Excrement And Its Renewable Energy Products, Ahmad Munjin Nasikh, Nur Faizin, Eli Hendrik Sanjaya, Achmad Sultoni, Cecep Soleh Kurniawan

Nusantara Halal Journal

Energy consumption continues to increase following the escalation of economic growth worldwide. The U.S. Energy Information Administration predicts global energy consumption will increase by 50% from 2018 to 2050, with the highest increase in Asia. But up to recently, coal and oil are still the primary sources of energy. Thus, a novel and renewable alternative energy is a necessity. Biomass is one of the most abundant renewable energy sources that come from various sources. However, the Muslim world population feels the need for an answer to the halal status of this energy source. This paper examines Islamic classical and modern …

Many Hands Make Light Work: Restoring Edu-Economical Debts For Black Males, Joyice Robinson Myers

VA Engage Journal

A college degree is closely linked to economic stability, yet only 20% of Black men in the United States hold a bachelor’s degree or higher. These disparities are not accidental; they are the cumulative result of systems that have systematically denied Black males equitable access to educational and economic opportunity across generations. This systematic review examines the compounding relationship among family structure, educational attainment, and economic standing for Black males, and considers what restoring that relationship could look like in practice. I integrate three theoretical frameworks—Education Debt (Ladson-Billings, 2006), African American Male Theory (Bush & Bush, 2013), and the R³ISE …

Establishment Of Age-Specific Reference Intervals For Ca 19-9 And Cea: A Retrospective Analysis Of The Saudi Population, Abrar Ashi, Shmoukh Alghuraibi

The Journal of King Abdulaziz University: Science

Introduction: Accurate interpretation of serum marker measurements is essential in clinical laboratory practice. Carbohydrate antigen 19-9 (CA 19-9) and carcinoembryonic antigen (CEA) are widely used biomarkers, yet their serum concentrations may be influenced by demographic and non-malignant factors. This study aimed to establish age- and gender-stratified reference intervals (RIs) for a Saudi population and quantify the impact of these local limits on diagnostic specificity and stewardship.

Methods: We retrospectively analysed 1,567 adult laboratory results (aged 15–100) from nationwide diagnostic centres. This study followed the CLSI EP28-A3c guidelines for the indirect estimation of reference intervals. Statistical analysis included Kruskal–Wallis and Mann–Whitney …

Integration Of Endemic Economic Cereal And Legume Crops In Jazan, Saudi Arabia Based On Pathogenic Fungi As A Taxonomic Study, A. El-Shabasy

The Journal of King Abdulaziz University: Science

This review evaluates the relation between fungal disease of the most important economic plants at Jazan region, Saudi Arabia and phylogenetic plant taxonomic values. This study provides the full information on the status of fungal diseases with comparative analysis among different species related to the same families. The review highlights on environmental impacts on fungal disease dispersion, virulence and pathogenicity besides the plant morphological characters. It refers to the adaptation of plants at their habitats as well as the status of fungal biodiversity among studied plant species.

Potential Protective Effects Of Okra (Abelmoschus Esculentus) Seed Oil Against Cadmium-Induced Oxidative Lipid Damage In Male Rats, Amani Ahmad Rifai Filimban, Nada Abdulkareem Batais

The Journal of King Abdulaziz University: Science

Objectives: To investigate the protective effect of okra seed oil against cadmium-induced toxicity in male Wistar rats.

Methods: Twenty-four male Wistar rats (8-weeks old, average 120g) were divided into four groups (n=6): Control/ Received deionized water. Cadmium/ Received 5 mg/kg/day of cadmium chloride (CdCl₂) orally. Okra Seed Oil/ Treated with 800 mg/kg/day of okra seed oil. Okra Seed Oil + Cadmium/ Received okra seed oil followed three hours later by CdCl₂. Treatments were given daily. Lipid profiles and antioxidant markers were measured to assess metabolic effects.

Results: Cadmium exposure caused significant dyslipidemia, characterized by elevated levels …

Insect Succession And Habitat Influence On Decomposition In Yanbu Industrial City, Western Saudi Arabia: A Baseline Study For Forensic Application, Abdullah A. Daghar, Abdullah G. Alghamdi, Majed S. Alrefaei

The Journal of King Abdulaziz University: Science

Forensic entomology plays a vital role in medico-legal investigations by providing key insights into post-mortem interval (PMI) estimation through the ecological succession and developmental patterns of necrophagous insects. Despite global advancements in this field, forensic entomological data in arid regions such as Saudi Arabia remains scarce and fragmented. This study investigates the diversity, abundance, and seasonal fluctuations of forensically important insect taxa across four ecologically distinct environments,desert, coastal, agricultural, and urban in Yanbu Industrial City, western Saudi Arabia. Field experiments were conducted using rabbit carcasses as decomposition models, exposed systematically across seasons. Insects were collected and morphologically identified. Results revealed …

Ziziphus Oxyphylla Edgew. A New Record In Arabian Peninsula From South-Western Mountains Of Saudi Arabia, Tawfiq Alfaifi, Lamiaa F. Shalabi

The Journal of King Abdulaziz University: Science

For the first time, the current study identifies Zizphus oxyphylla Edgew. plant collected from southwestern mountains of Saudi Arabia, Al Hashr and Faifa. Complete morphological description for the plant, taxonomic notes, location and distribution maps, photographs for plant parts, habitats and population data are included. Data collected from published literature, formal taxonomic websites, geographical affinities, ecological similarities were reported as strong evidences which confirmed the identification of Ziziphus oxyphylla plant as a new addition to the flora of Saudi Arabia and Arabian Peninsula.

Heavy Metal Contamination In Red Sea Hamour Fish: Bioaccumulation Patterns, Toxicological Impacts, And Microbial Community Disruption, Haifa O. Aljuhani, Osamah A. Ahmad, Ashwaq R. Almohammadi

The Journal of King Abdulaziz University: Science

Red Sea heavy metal pollution lately poses a serious threat to human health and ecological integrity. The present research review examines the several effects of heavy metal contamination on the economically important Hamour fish (Epinephelus spp.), a major bioindicator species because of its benthic feeding habit and great bioaccumulation potential. Where the industrial activities, hydrocarbon exploration, desalination effluent, and coastal urbanization have produced continuous pollution vectors, promoting bioaccumulation via gill absorption, food intake, and dermal absorption in Hamour tissues. Our work demonstrates complicated toxicological effect comprising oxidative stress, hematological malfunction, immunosuppression, neurotoxicity, reproductive impairment, and genotoxic damage. Consequently, heavy …

The Effect Of Black Pepper (Piper Nigrum) Extract On Lipid Profile In Streptozotocin-Induced Diabetic Rats, Amani A.R. Filimban, Khulud A. Wathi

The Journal of King Abdulaziz University: Science

Objective: This study aimed to evaluate the hypolipidemic effect of black pepper (Piper nigrum) aqueous extract on lipid profile parameters in streptozotocin (STZ)-induced diabetic rats.

Methods: Eighteen adult male Wistar rats were randomly assigned to three groups: a control group, a diabetic group induced by STZ, and a diabetic group treated with black pepper extract (50 mg/kg/day) for 30 days. Total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and high-density lipoprotein (HDL) levels were measured using ELISA. Statistical analysis was performed using ANOVA with Tukey's post hoc test and effect size estimation.

Results: The diabetic group exhibited significantly …

Selective Separation Of Eriochrome Black T Onto Cork From Marine And Tap Waters: Kinetic, Isotherm And Thermodynamic Study, M. A. Alsolami, Z. M. Saigl

The Journal of King Abdulaziz University: Science

Synthetic dye contamination of waterways poses a serious threat to human health and the environment. Eriochrome Black T (EBT) is a persistent azo dye that is especially dangerous because of its toxicity and chemical stability. This study evaluates cork as a cost-effective and environmentally responsible biosorbent for the removal of EBT from aquatic systems. Experimental observations confirmed that adsorption equilibrium was achieved within 25 minutes at an optimal pH of 4. Kinetic using pseudo-first-order, pseudo-second-order, and Elovich models revealed that the pseudo-second-order model yielded the most accurate fit (k₂ = 0.2482 g/mg.min), implying that chemisorption is the primary …

Diversification Of Ghost Electric Fishes (Gymnotiformes, Apteronotidae) In Tropical South America: How Traits And Environmental Factors Constrain Macroevolutionary Diversification, Jonathan Gifford Allen

Doctoral Dissertations

Neotropical electric fishes (Apteronotidae) display remarkable phenotypic and ecological diversity, offering an exceptional system for studying macroevolutionary processes in freshwater environments. Here I investigate the morphological, ecological, and historical factors shaping diversification in the clade Navajini, with a focus on craniofacial evolution, species delimitation, and biogeographic patterns. First, using high-resolution micro-CT scans, 3D geometric morphometrics, and phylogenetic comparative methods, I analyze skull shape variation across Navajini. Key traits resulting from heterocephaly exhibit strong phylogenetic signal and reflect functional differentiation among genera. Sexual dimorphism contributes significantly to cranial disparity in some lineages, while others show conserved, modular patterns likely tied to …

Blended Family Dynamics And Executive Functioning In Preschoolers: A Cross-Sectional Study, Kayla Butler

Walden Dissertations and Doctoral Studies

No abstract provided.

Storytelling, Gender, And The Double-Empathy Problem, Annie Rogers

Theses and Dissertations

Storytelling has been proposed as a meaningful way to facilitate empathy and connection, particularly across neurotypes. The present study examined whether a live storytelling event influenced perceptions of the autism community, empathy, and interpersonal connection, while also exploring differences on biological sex and levels of autistic traits. Participants completed pre- and post-event measures assessing relationship perceptions and connection, along with standardized measures of empathy and autistic traits. Results showed a significant increase in positive perceptions of the autism community and perceived closeness to storytellers after the event. Engagement, emotional impact, openness, and motivation to support the autism community were all …

Spectator 2026-06-04, Editors Of The Spectator

The Spectator

No abstract provided.

Using Single Cell Multi Omics And Spatial Transcriptomics To Characterize The Inflammatory- Fibroblast Axis In Cardiovascular Disease, Junedh Mahesh Amrute

Arts & Sciences Graduate Student Theses and Dissertations

Despite tremendous progress in cardiovascular research, we still have an incomplete understanding of the precise cell states, transcriptional programs, and regulatory mechanism involved in atherosclerosis and heart failure. I hypothesize: (1) in human coronary artery disease, genetic variation acts in a cell state specific manner to perturb the gene regulatory network and drive smooth muscle cell and fibroblast trans- differentiation into the neo-intima and (2) macrophages signal to fibroblasts via IL-1b through a Runx1 gene regulatory network to drive activation and cardiac fibrosis. To test these hypotheses, we will employ a reverse translation paradigm: starting with human tissue, we will …

Distribution, Abundance And Habitat Utilization Of Sea Turtles In The Northern Gulf Of Mexico, With An Emphasis On Coastal Mississippi, Theresa Rose Madrigal

ETDs from 2020-2029

The Gulf of Mexico represents important habitat for a variety of sea turtle species. This includes habitats for the various life history stages ranging from the oceanic stage of hatchling and post-hatchling turtles, neritic subadults, to the adult foraging and reproduc-tive stages. In contrast to many areas of the Gulf of Mexico, there has been a limited amount of data reported on sea turtle nesting as well as sea turtle foraging and develop-mental habitat in the north central Gulf of Mexico. This thesis includes two studies which investigate the importance of the coastal areas of Mississippi as sea turtle habitat. …

Growing Pains: The Loss Of Plasticity To Extreme Anoxia In Developing Embryos Of Austrofundulus Limnaeus, Patrick Ryan Clouser

Dissertations and Theses

Oxygen plays a pivotal role for most animal life on Earth, so much so that even short exposures to no oxygen, anoxia, can have severe effects on the animal's wellbeing. Conversely, aerobic recovery after anoxic insult can be just as detrimental. Some animals are the exception to this rule and demonstrate survival through anoxia and recovery. There has been a great deal of research around anoxia tolerant animals, but what remains unclear are the genetic underpinnings that determine the anoxia tolerant phenotype. RNA sequencing allows for the quantification of RNA transcripts within a sample, which can indicate if a gene …

Bad Mothers In Translation: Early Motherhood In Contemporary Turkish Editions, Merve Sevtap Süren

Journal of Feminist Scholarship

This article examines how three recent Anglophone novels of early motherhood, namely, Szilvia Molnar’s The Nursery (as Süt Lekesi), Rachel Yoder’s Nightbitch (as Gece Kancığı), and Claire Kilroy’s Soldier Sailor (as Asker ile Denizci), circulate in Turkish translation in a context shaped by pronatalist moral economies. Pairing peritextual analysis (covers, back-cover copy, blurbs, and bio notes) with close readings of selected key scenes of postpartum crisis, feral transformation, and toddler-year burnout, I show how Turkish editions both render and manage maternal negativity: translation choices modulate voice, affect, and register, while peritexts frame these mothers for local readability …

“Subjugated Knowledge And Narrative Justice”: An Interview With Grace M. Cho, Anupama Arora, Yuni Kim

Journal of Feminist Scholarship

No abstract provided.

Beyond Liberal Apologies, Toward Abolitionist Trans Politics, Koda Sokol, Kaden Paulson-Smith

Journal of Feminist Scholarship

In the wake of Trump’s second election, the liberal fantasy of a benevolent state reared its head: the right policy, politician, or police officer will end anti-trans oppression. This article heeds the warning from generations of abolitionists before us that violence is not a defect of the state but endemic to it. By consequence, reforms that strengthen the state by expanding avenues for criminalization, resourcing the police, and incorporating more people into the military further jeopardize those subject to premature death, trans or otherwise. The current U.S. political regime’s overt cruelty provides an opening for widespread reckoning with the state’s …

From Dysbiosis To Resistome: Antibiotic-Driven Selection Pressure And Multi-Class Resistance Gene Enrichment In The Autism Gut Microbiota, Dalia Abuljadayel, Reem Farsi, Bodoor Alotibi, Asma Almuhammadi

The Journal of King Abdulaziz University: Science

Autism Spectrum Disorder (ASD) is associated with alterations in the composition of the gut microbiota, which have been implicated in neurological manifestations via the gut–brain axis. Early-life exposure to antibiotics constitutes a key environmental factor shaping microbiota development; however, the resistome profile underlying ASD-associated dysbiosis remains insufficiently defined. In this metagenomic investigation, we assessed the abundance and diversity of antibiotic resistance genes (ARGs) in fecal samples obtained from four children with ASD and their four neurotypical siblings. High-throughput shotgun sequencing generated 10-15 Gb of data per sample. Resistome characterization was performed using the Comprehensive Antibiotic Resistance Database (CARD) and the …

Novel Meristic Changes In The Flowers Of Ziziphus Spina-Christi (Rhamnaceae), Tawfiq Alfaifi

The Journal of King Abdulaziz University: Science

The study focuses on the Flower meristic changes that occur in Ziziphus. DNA analysis was conducted for the Ziziphus species in the study area to determine the species. Then, the flowers were pictured for the species that frequently exhibit changes in flower structure. The results show that Z. spina-christi exhibits this phenomenon while the other species do not. In addition, the study shows that not all flower organs change; the ovary retains the same structure in both pentamerous and tetramerous flowers.

Differential Gene Expression Profiling Of Drought-Tolerant And Sensitive Rice Genotypes Identifies Key Regulatory Networks And Metabolic Pathways, Najla Bint Saud Al-Saud

The Journal of King Abdulaziz University: Science

Drought stress represents a critical constraint to rice productivity worldwide, necessitating a comprehensive understanding of the molecular mechanisms underlying stress tolerance. This study employed RNA sequencing to investigate drought-responsive transcriptional networks in root tissues of two contrasting rice genotypes: Azucena (drought-tolerant) and IR64 (drought-sensitive). Twenty-day-old seedlings were subjected to 14-day drought stress treatment, and transcriptomic profiles were analyzed using high-throughput sequencing. Quality-filtered reads achieved >95% Q30 scores with alignment rates of 94.48–96.55% to the reference genome. Differential expression analysis identified 30,419–31,052 differentially expressed genes across four comparison groups, with the drought-sensitive IR64 exhibiting approximately 15% more differentially expressed genes (DEGs) …

Algal-Mediated Green Synthesis Of Silver Nanoparticles And Their Antibacterial Activity, Yahya B. Alyoubi, Hassan A. Ewais, Magda M. Aly, Walied M. Alarif

The Journal of King Abdulaziz University: Science

A green, low-cost, and straightforward method was implemented for the synthesis of silver nanoparticles (AgNPs) using Digenea simplex Algal Extract (D. simplex). The formation of AgNPs was initially indicated by a golden yellow color of the solution and UV-Vis λ_max at 410 nm. Key factors such as reaction time, temperature, pH, concentrations of Ag⁺ and algal extract was also investigated. FTIR analysis confirmed the presence of alga-derived biomolecules which assets the reduction of silver ions. TEM analysis revealed the successful synthesis of spherical AgNPs with an average size of 12.86 ± 4.84 nm. The biosynthesized AgNPs exhibited a …

Rules And Roles In The Political Economy Of Peatland Fires In Ketapang, West Kalimantan, Indonesia, Ali Yansyah Abdurrahim, Atiek Widayati, Edi Purwanto, Meine Van Noordwijk

Forest and Society

Peatland fires in Indonesia represent a critical socio-ecological system failure, generating transboundary haze, biodiversity loss, and severe human health impacts. In Ketapang Regency, West Kalimantan, the persistence of fires illustrates the tensions between protection and production in the local political economy. On the one hand, peatlands are legally designated for conservation under national regulations and regional initiatives, such as Regulation No. 48/2023 on peatland fire prevention. On the other hand, they remain under sustained pressure from the expansion of palm oil, transmigration schemes, and local livelihood needs. This study applies a political economy (stakes) and political ecology (status-power) lens to …

The Alaska Wolf War: Action On The Prince Of Wales Island Complex, Edward A. Fitzgerald

Alaska Law Review

This Article examines Alaska's management of the Alexander Archipelago wolf on the Prince of Wales Island Complex, pursuant to constitutional and statutory requirements. It begins by reviewing the history of unsuccessful efforts to declare the wolf a threatened or endangered species under the Endangered Species Act. It then analyzes Bennett v. State, which focused on the changed management regime and devastating wolf harvest of the 2019–20 season. The Article argues that the district and Alaska Supreme Court's decisions in the case were flawed because they failed to properly implement the "hard look" doctrine.

Intrathecal Antibody Synthesis - Reiber Method Revisited, John J. Halperin, Dane Granger

Department of Neurology Faculty Papers

BACKGROUND: CSF immunoglobulin (IgG) often informs diagnosis in CNS inflammatory disease- qualitatively (oligoclonal bands; OCBs), or quantitatively (CSF: serum IgG: albumin, e.g. IgG index). Most US laboratories estimate excess CSF IgG using linear models, most in Europe, Reiber's hyperbolic model - the latter often also incorporated into CSF pathogen-specific immunoreactivity calculations. We compared Reiber hyperbolic and linear approaches.

METHODS: Required data were available for 1,872 samples, Lyme-specific data for 1,365. We compared linear and Reiber's hyperbolic models to determine which better describes normal CSF: serum IgG/albumin, assessed correlations with OCBs using ROC analysis and compared Lyme-specific antibody indices (AI) by …

Comparison Of Fish Biomass And Fish Carbon Content Associated With Reef Sites At The Rio Grande Valley Artificial Reef In The Gulf Of Mexico, Allison K. White, Md Saydur Rahman, Richard J. Kline

School of Earth, Environmental, & Marine Sciences Faculty Publications

As global fisheries stocks have decreased due to overfishing and climate change, artificial reefs have gained significant attention. In addition to providing or restoring habitat, artificial reefs may serve as carbon capture sinks and potential climate mitigation strategies. The Rio Grande Valley (RGV) Reef is an artificial reef located in the northwestern Gulf of Mexico off the coast of Texas. The RGV Reef area spans 1,650 acres and is comprised of hundreds of groupings of recycled and pre-formed materials ranging from low relief (1–2 ft) to high relief (8–30 ft) reef structures. This reef provides a variety of novel habitat …

Trial Of Oxaloacetate In Als (Toals), Katie Lillig, Andrew Heim, Jeffrey Statland, Mazen M. Dimachkie, Russell H. Swerdlow, Sachini P. Karunaratne, In-Young Choi, Phil Lee, Edina Kosa, Abdulbaki Agbas, Heather M. Wilkins, Richard J. Barohn, Omar Jawdat

Faculty and Staff Publications

Background: Mitochondrial dysfunction is a critical therapeutic target in amyotrophic lateral sclerosis (ALS). Oxaloacetate (OAA) is a promising candidate therapy as it crosses the blood brain barrier, reaches motor neurons, and enhances mitochondrial bioenergetics with positive preclinical data in ALS.

Methods: We conducted a prospective, phase 1B, dose escalation study using a standard 3+3 design to assess the safety profile and determine the maximum tolerated dose. Dose-limiting toxicity (DLT) was defined as any serious adverse event (SAE) requiring hospitalization or any adverse event (AE) attributed to OAA that required discontinuation of the medication. Dosages evaluated started at 1000 mg twice …