Digital Commons Network^™

Design And Parametric Testing Of A Transimpedance Amplifier For Low-Power Biomedical Applications, Stanlon Tan, William Chung, Brandon Wu

Electrical Engineering

This project developed and evaluated an optical sensing system for detecting changes associated with glucose concentration. The system combined a laser-diode, cuvette sample holder, photodiode, resistive-feedback transimpedance amplifier, high-resolution analog-to-digital converter, and microcontroller. Parametric testing evaluated the effects of input current and feedback resistance on transimpedance gain, output range, and linearity. Firmware was developed to configure the ADC, average repeated conversions, monitor measurement variation, convert raw digital counts into voltage using a source-meter calibration equation, and compare sample measurements with a water reference. A cuvette enclosure maintained alignment between the laser-diode, sample, and photodiode while reducing external optical interference. Testing …

Simulation Of Silicon Neurons With Memristive Synapses For Ai Accelerators, Marcus Ivey, Kelvin Shi

Electrical Engineering

This project seeks to design and simulate a neuromorphic spiking neural network (SNN) that implements the logical AND and logical OR operation through the interaction of a Leaky Integrate-and-Fire (LIF) output neuron and memristive synapses modeled using the Biolek formulation. Two pulsed inputs are transmitted through memristive devices whose conductance serves as the synaptic weights. A supervised Hebbian training strategy, implemented in MATLAB, is employed to adjust the synaptic conductance according to the Hebbian delta rule. The proposed framework demonstrates how elementary logical computation may arise from biologically motivated learning processes embedded in hardware-realistic neuromorphic circuits. The study provides a …

Ugv-Based Vertebrate Pest Deterrence In Vineyards: Vision-Guided Row Patrol And Navigation, Candace Qualls, Karina Wilson, Ben Badhorn

Electrical Engineering

An increase in agricultural demands and the need to sustainably protect crops has created a need for autonomous navigation through a vineyard with a verified pest detection and deterrence system. Developing this solution revealed several challenges. First, the robot must reliably navigate through structured, repetitive vineyard rows. Second, pests must be detected accurately under changing environmental conditions. Lastly, the system must respond with a chosen deterrent within an appropriate time window, all while minimizing false triggers. To address these challenges, this project uses a Husky A200 unmanned ground vehicle equipped with a 2D LiDAR sensor, an Intel RealSense RGB camera, …

Portable Food Pasteurization Using Pulsed Electric Fields (Pef), Thomas E. Mcmillan Iii

Electrical Engineering

Foodborne illnesses remain a significant public health concern, motivating continued development of alternative food pasteurization technologies. Pulsed electric field (PEF) treatment is a non-thermal pasteurization method that inactivates microorganisms through electroporation while minimizing thermal degradation of food products. The long-term objective of this project was development of a portable PEF food pasteurization system.

An iterative design approach was used to investigate generation of the high-voltage pulses required for PEF treatment. Multiple pulse forming network topologies were evaluated through simulation, leading to selection of a solid-state Marx generator architecture. A low-voltage five-stage prototype was designed, constructed, and tested to validate the …

Vlsi Spike Encoder For Spiking Neural Networks With 4-Bit Sar Adc, Jack Marshall, Wyatt Tack, Cameron Young, Ryken Thompson

Electrical Engineering

A spike encoder forms the interface between sampled data, such as image data or a sensor signal, and a spiking neural network by converting numerical input samples into discrete spike events. Unlike conventional artificial neural networks, spiking neural networks use spare, even-driven computation instead of continuous-valued activations. This makes them attractive for low-power embedded systems, biomedical electronics, and other edge applications where energy consumption, physical area, and thermal limits are important design constraints.

This project develops a modular spike encoder architecture for spiking neural networks with selectable support for temporal, rate, multi-spike, and delta encoding. Prior work has shown that …

Articulator Volume 32, Issue 2

Metro Denver Dental Society Articulator Magazine

The 2nd Quarter 2026 issue of The Articulator explores the growing intersection between oral health and whole-body wellness, with a focus on oral-systemic health, interdisciplinary collaboration and the role of dentistry in preventive medicine. Articles include:

• A perspective from Dr. Brett Kessler examining what true medical-dental integration would require, including reimbursement reform, collaborative care models and expanded recognition of dentistry’s role in systemic health.
• An evidence-based article from Ms. Anne O. Rice exploring the connection between periodontal disease, inflammation and Alzheimer’s disease, including the role of dentistry in dementia risk reduction and preventive healthcare.
• Insights from Ms. Lani McBeth on …

Detection And Evaluation Of Hazardous Mercury Contamination In Various Biological Samples, Krish Italiya

Biochemistry and Molecular Biology

Mercury is a toxic environmental pollutant that threatens ecosystems and human health. This study investigates mercury contamination in Lactuca sativa (lettuce) and selected fish species, including tuna and salmon, focusing on plant responses and the limitations of X-ray fluorescence (XRF) analysis. In a controlled experiment, lettuce plants were exposed to mercury to evaluate uptake and toxicity, and XRF spectroscopy was used for quick, non-destructive elemental analysis. Results confirmed mercury accumulation in lettuce, along with visible stress symptoms such as leaf yellowing, purple pigmentation, and tissue damage. Mercury was not detected in tuna and salmon samples, likely due to concentrations below …

Screening Tools For Maternal Mental Health In Africa: A Systematic Review, Joyce Jebet, Irene Mageto, Benard Mutwiri, Abednego Ongeso, Ruth Wagathu, Rose Maina, Denis Munene, Kawira Kithuci, Peter Gatiti

School of Nursing & Midwifery, East Africa

Background:

Maternal health during pregnancy and the postnatal period encompasses mental health, which is a key aspect in enhancing a positive outcome. Despite screening for other possible complications during pregnancy and the postnatal period, very little attention has been paid to screening for mental health. Screening is a key tool in early diagnosis and, eventually, timely diagnosis and management in cases where complications arise.

Aim:

This study aimed to assess the available maternal mental health screening tools and compare the outcome on their utilization during pregnancy and postnatal periods in the African continent.

Methodology:

This was a …

Investigating The Effects Of Increased O-Glcnaylation On Pathology In Alzheimer’S Disease, Melissa Louise Garcia

ETDs from 2020-2029

Alzheimer’s disease (AD) is currently the 7th leading cause of death, with few treatment options. It is known that AD pathology begins 20-30 years before clinical symptoms manifest. Some of the earliest pathological changes occur in glial cells of the hippocampus, causing them to become chronically reactive, as well as the accumulation of Amyloid-β (Aβ) in the hippocampus and hyperphosphorylated Tau (pTau) in the locus coeruleus, resulting in dysfunction of the noradrenergic (NA) system. Preclinical studies have shown promise in the abilities of the post-translational modification O-linked β-N-acetylglucosamine (O-GlcNAc). O-GlcNAc is a tightly regulated reversible enzymatic modification controlled by the …

Elucidating The Role Of The Rnf20 Histone Modifier In Pancreatic Beta Cells, Tanya Hans Pierre

ETDs from 2020-2029

Diabetes is defined as a loss of functional beta cell mass. It is classically categorized into Type 1 Diabetes (T1D), immune-mediated beta cell destruction and Type 2 Diabetes, which is characterized by whole body insulin resistance alongside beta cell dysregulation. The incidence of diabetes worldwide has risen annually. Despite the presence of therapeutic interventions, diabetes’ heterogeneity can prompt ineffective glycemic control and the development of diabetes-associated comorbidities. For that reason, new approaches to glycemic control for individuals with diabetes are required. One approach to restore glucose homeostasis is beta cell replacement therapy, in which stem cells are programmed into beta-like …

The Association Of Motherhood And Maternal-Related Life Events And Cardiovascular-Related Health, Disease Events, And Mortality, Taishayla Mckitt

ETDs from 2020-2029

More than 40% of U.S. women have cardiovascular disease (CVD), and nearly half have at least one major risk factor. Sparse evidence exists related to the role of childrearing (regardless of prior pregnancy) on CVD. A recent literature review highlighted the influence of reproduction on CVD and health and identified opportunities for advancement. At present, it has yet to be discovered from prospective epidemiologic studies the extent to which parenting and maternal events have influence on cardiovascular health and clinical events. It has been demonstrated that parous women have greater prevalence of cardiovascular risk factors (e.g., short sleep duration and …

Balancing Act: How Graduate Student Mothers Navigate Dual Roles, Jessica Seymour

ETDs from 2020-2029

Graduate student mothers represent a growing but often overlooked population within higher education. While research has examined the experiences of undergraduate student parents, significantly less attention has been given to graduate students who balance academic responsibilities with motherhood. This study explores the experiences of graduate student mothers enrolled at public four-year institutions, focusing on the institutional, financial, and social barriers that shape their academic success and participation in campus life. Using a phenomenological approach, this research seeks to understand how graduate student mothers navigate the dual roles of parenting and pursuing advanced degrees. The study employs a Borderland Theoretical Framework …

Comparative Evaluation Of Translucency, Fluorescence, And Structural Analysis Of 3d-Printed Vs. Conventionally Fabricated 3y, 4y And 5y Zirconia, Surabhi Chhabra

ETDs from 2020-2029

Statement of Problem: Additive manufacturing has emerged as an alternative to conventional milling for zirconia-based dental restorations because of its potential to reduce material waste and increase design flexibility. However, whether 3D-printed zirconia can provide optical and structural properties comparable with those of conventionally milled zirconia for esthetic applications remains unclear. Purpose: The purpose of this in vitro study was to compare the optical properties of 3D-printed zirconia and conventionally milled 3Y, 4Y, and 5Y zirconia, as measured by translucency and fluorescence, and to evaluate their structural characteristics, as measured by density, porosity, phase composition, and surface morphology. Materials and …

Recognizing Patients In Places: A Multilevel Analysis Of Severe Heat-Related Illness Risk In Birmingham, Al, Andria Cimino

ETDs from 2020-2029

Socially marginalized people face a higher risk of adverse health outcomes from extreme heat—as many as 12,000 U.S. deaths a year are attributable to heat-related illness (HRI), a preventable but multifactorial condition. Where one lives plays a critical role in HRI incidence, with evidence linking historically segregated and disinvested urban environments to a higher risk. The literature also suggests that Black adults experience worse HRI outcomes than non-Hispanic White adults, and that men are often, though not always, at higher risk than women. Individuals with heat-sensitive conditions and socially isolated adults also face elevated risk. Yet the mechanisms by which …

Protein Glycosylation In Natural And Synthetic Minimal Genome Mycoplasmas, John Sanford

ETDs from 2020-2029

Mycoplasmas are cell wall-less bacterial symbionts with remarkably streamlined genomes. Mycoplasmas offer two intriguing model organisms for studying concepts of minimal life. Mycoplasma genitalium has streamlined its genome to 580-kbp while maintaining virulence to suit its niche of parasitizing the human urogenital tract. The J. Craig Venter Institute has synthesized and transplanted a 543-kbp genome into a recipient cell, resulting in a non-pathogenic organism termed JCVI-syn3A. The conservation of a biological process in M. genitalium and JCVI-syn3A strongly implies an essential function in mycoplasmas, and potentially all life. Despite common thought of mycoplasmas being the simplest cells, much of their …

Stakblocks, Micah Satoshi Inoshita, Ava Rose Doerschlag, Cody J. Ellis, Zach M. Lawton, Fernando M. Nalin, Nicholas Humphrey, Aiden Reed Anderson, Sara Maya Suratkal

Mechanical Engineering

Researchers developing sustainable building materials from agricultural waste need a faster way to prototype and evaluate small-scale samples under controlled temperature and pressure before scaling to production. Sponsored by Professor Pete Schwartz of Cal Poly San Luis Obispo, whose work focuses on sustainable technology for developing communities, this project aims to create a prototype testing device for researchers studying agricultural-waste bricks, with the University of Malawi as a potential future testing partner. The final product is intended to inform improved future designs rather than serve as a production-ready device, ultimately supporting the development of affordable, sustainable building materials for communities …

Glassjelly: Designing A Skincare App Built Around Understanding, Tracy Le

Graphic Communication

Skincare apps today are built around selling products, not building knowledge—and for beginners, that gap is real. Without clear explanations of ingredients or routines, users are left to figure it out alone, often in ways that don’t account for their skin tone, skin type, or cultural backgrounds. Glassjelly was created to fill that gap, offering a skin assessment and ingredient education experience that puts understanding before promotion, and the individual before the trends.

The Effects Of Adverse Childhood Experiences On Female College Students' Social Emotional Development: Is Flourishing Possible?, Kaylee Kirkwood

University Honors Theses

Adverse childhood experiences are events of trauma and abuse that occur prior to age eighteen. High rates of sexual violence against girls and female undergraduate students inspired this study to explore how trauma may impact development and overall college experience. This thesis employed a small exploratory pilot study to investigate childhood trauma and social-emotional development among a small sample of female college students (ages 18-25; n = 41). Participants recruited through the Prolific Database completed an online Qualtrics survey consisting of screeners, demographic questions, measures of trauma history and emotional functioning, and optional open-ended experience-based questions. Measures were guided by …

Viruses Causing Panleukopenia In Domestic Cats: A Review Of Feline And Canine Parvoviruses, Simon Colby

University Honors Theses

Parvoviruses remain among the most important viral pathogens in domestic cats today. Despite this, there is much confusion around which parvoviruses can infect cats, and what extent of disease they can cause. One of the two parvoviruses infecting cats, canine parvovirus type-2 (CPV-2), likely evolved from the other parvovirus infecting cats, feline parvovirus (FPV). These viruses differ at only a few places in their genomes, and share the method of cell entry via the transferrin receptor. The disease caused by FPV has been well characterized in cats, but disease caused by CPV-2 is more obscure. Additionally, current testing methods for …

Interrupted By Design: The Impact Of Push Notifications On Stress And Task Performance, Mia Hohmann

University Honors Theses

As digital communication becomes unavoidable at work, notifications have become one of the most common and overlooked sources of interruption. Drawing from current technostress literature, this study investigates how notifications impact acute and perceived stress as well as task speed and accuracy. In an experimental setting, employed university students (N = 35) completed a data-entry task while receiving either no notifications, task-relevant notifications or task-irrelevant notifications to examine how different types of digital interruptions influenced stress and performance. Stress was measured through a pre- and post-task survey and performance was assessed through both speed and accuracy. Although results showed significant …

The Dolor: How A Generation Of Women Quietly Lost Their Children, Alexis Mclean

University Honors Theses

This thesis is an exploration of the phenomenon of increased adoption rates between the years of 1945 and 1973 and attempts to establish a cohesive explanation for and image of the experience of these birth mothers. My research found that adoptions during this time period are generally characterized by the utilization of maternity homes, coercion, and secrecy. The typical birth mother during this time was white and middle class, emblematic of the motivations of their adoptions: to maintain an idealist image of their motherhood and maintain socioeconomic status. Despite this position framed by privilege, these women too often report having …

Applications Of Prior And Novel Computational Tools In Mental Health Treatment, And Their Potential To Uncover The Explanatory Gap, Ambika Vyas

University Honors Theses

The explanatory gap is a widely discussed concept in scientific and philosophical literature. In neuroscience, the solution to the explanatory gap is highly sought out, but the general consensus is that it is unsolvable. Numerous articles discuss the explanatory gap alongside computational tools and how these tools could aid neuroscientists in uncovering the mental health explanatory gap. However, significant developments in machine learning have been made since 2020, coinciding with the rise in Large Language Models (LLMs). This thesis is a literature review on computational methods, tools, and devices developed and utilized by researchers to improve how mental health disorders …

Exploring The Durability Of Marine Picocyanobacterial Microcolonies, Erik Swanson

University Honors Theses

Picocyanobacteria of the genus Synechococcus are widespread aquatic photoautotrophs that play essential roles in primary production and carbon cycling. Some Synechococcus strains form multicellular microcolonies, but the mechanisms of cell-to-cell attachments and structural durability of these microcolonies remain poorly understood. This research investigated the physical durability of microcolonies in two marine Synechococcus strains (CC9605 and CC9311) using physical disruption treatments. Cultures were subjected to vortexing and sonication treatments, and populations of single cells and microcolonies were quantified using flow cytometry based on differences in measures of size. Results indicated that strain CC9605 showed no significant treatment effect, whereas CC9311 displayed …

Developing A High-Resolution Off-Axis Common-Mode Digital Holographic Microscope, Lucy Cook

University Honors Theses

Off-axis digital holographic microscopy (DHM) is a powerful tool for 3D, non-invasive live-cell tracking without moving parts. However, traditional setups face an inherent dilemma: split-path interferometers offer high spatial resolution but poor temporal stability, while more stable common-mode configurations are historically limited to lower numerical aperture (NA) regimes. This thesis bridges that gap by scaling a common-mode DHM architecture into a high-resolution benchtop instrument featuring NA = 0.65 objectives, paired with a high-power 520 nm laser source to combat transmission losses and sustain imaging frame rates across an expanded optical footprint. We map the multi-variable design space required to satisfy …

Grief, Silence, And Surveillance In Academic Settings, Rakhi Grey

University Honors Theses

This study examines how grief is silenced, monitored, and regulated within higher education settings. Drawing on semi-structured interviews with undergraduate students who experienced the death of someone significant, this study explores how institutional expectations surrounding productivity, professionalism, emotional control, and academic functioning shape grief disclosure, emotional expression, and help-seeking behaviors. Using a critical theoretical framework informed by concepts of disenfranchised grief, legitimacy hierarchies, and surveillance, findings suggest that grief within higher education is not simply individually experienced, but socially and institutionally regulated. Participants described academic environments that often left little space for ongoing grief, requiring students to compartmentalize emotional distress, …

Psychological Architecture: Evaluating The "Greenhouse Model" As A Structural Standard For Lgbtq+ Well-Being, Ava Lee

University Honors Theses

Traditional LGBTQ+ mental health frameworks often conceptualize psychological safety as a matter of individual endurance. This paper critiques this focus on adaptive resilience, which systematically shifts responsibility from institutions to individuals. To counter this, the study introduces "Psychological Architecture," a framework viewing social environments as constructed infrastructures that can either support or undermine queer well-being. The model contrasts performative "Glasshouses," which prioritize visibility over safety, with engineered "Greenhouses" that nurture sustainable safety through three sequential pillars: Authentic Representation (walls), Emotional Validation (insulation), and Vocal Activism (ventilation).

Grounded in the findings of a 2024 qualitative pilot study of a queer roller …

Fundamentalist Disorientations For Queer Subjects: Narrative And Theory, Betty Canoso

University Honors Theses

This thesis examines disorientation experienced by queer people who were raised in high-cost fundamentalist Christianity–people like me. Disorientation is a philosophical concept useful for examining specific intersections of human experience, like queerness and fundamentalism. Philosophers such as Sara Ahmed (2006) and Ami Harbin (2016) have been exploring the intersection of queerness and disorientation. Psychologists, sociologists and researchers from other disciplines are analyzing the interrelatedness of queerness and religion, and disaffiliation and deconversion from high-cost or high-control religions is another ongoing area of interest. Yet, despite widespread interest in these concepts, few have looked at instances of disorientation as they pertain …

"I Still Care About Her": Ambiguous Loss And Social Death In Substance-Affected Relationships, Margaret M. King

University Honors Theses

Substance use creates a ripple effect, affecting the individual as well as their family members. The struggles associated with problematic substance use result in feelings of ambiguous loss towards the substance using individual, a type of loss in which a person is still living but either psychologically or physically unavailable. This research explores the experiences of ambiguous loss in college students with loved ones struggling with substance use, examining how they are thrust into caregiving roles, experience support, and find meaning within their loss. Seven semi-structured interviews were held with adult college students who identified as having a loved-one struggling …

Shallow-Marine Crinoid Genera May Have Been More Resilient Across Permian Extinction Events In Terms Of Richness Than Deep-Marine Crinoid Genera, Amelia C. Kolstad

University Honors Theses

Throughout the Phanerozoic, one of the most successful phyla of marine invertebrates has been Echinodermata. Echinodermata was particularly successful throughout the Paleozoic, with class Crinoidea making up a majority of occurrences. The proportion of echinoderm occurrences that are crinoids declined massively at the end of the Permian and continued to decrease into modern day, never fully recovering. One of the factors thought to have been so important for crinoid success in the Paleozoic and their decreasing success throughout geologic time has been their propensity for success in shallow-marine environments, though crinoids also exist within deep-marine environments. This study seeks to …

Moving Beyond Traditional Cost Containment For Glp-1 Coverage Within Oregon's Proposed Universal Health Plan, Manoj Rajesh

University Honors Theses

In 2022, Oregon voters passed Measure 111, constitutionally mandating access to affordable health care. As the Universal Health Plan Governance Board (UHPGB) designs the state's proposed single-payer system, it faces an unprecedented financial vulnerability: the clinical demand for GLP-1 receptor agonists. These high-cost, indefinite-use medications for obesity and metabolic syndrome threaten to overwhelm fixed public budgets. Historically, both the Oregon Health Plan's Medicaid framework and commercial private insurers have relied on static cost-containment models—categorical exclusions, step therapy, and aggressive utilization management—that achieve short-term fiscal solvency at the expense of comprehensive preventative care. This thesis argues that to fulfill the mandate …