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2026

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The Development Of An In Silico Vaccine Design-Based E-Module To Improve Students' Biological Literacy, Qairinasherin Qwine Ferendi, Rusdi Rusdi, Hanum Isfaeni Jun 2026

The Development Of An In Silico Vaccine Design-Based E-Module To Improve Students' Biological Literacy, Qairinasherin Qwine Ferendi, Rusdi Rusdi, Hanum Isfaeni

Jurnal Pendidikan Sains

Low levels of biological literacy among students, particularly in biotechnology, highlight the need for innovative digital learning media that facilitate meaningful and contextual learning experiences. This study aimed to develop and evaluate an interactive biotechnology e-module based on in silico vaccine design to improve students’ biological literacy. The study employed Educational Design Research (EDR) using the Hannafin and Peck model, which consists of three phases: needs assessment, development, and implementation. The participants included 73 tenth-grade science students and one biology teacher from SMAN 68 Jakarta, Indonesia. The e-module was developed using Canva and Heyzine to create an interactive flipbook integrating …

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Developing Biodegradable Packaging Films And Beads From Agricultural Residues, Sandeep Paudel, Santosh Rijal, Srinivas Janaswamy, Madhav P. Nepal Jun 2026

Developing Biodegradable Packaging Films And Beads From Agricultural Residues, Sandeep Paudel, Santosh Rijal, Srinivas Janaswamy, Madhav P. Nepal

iLEARN Teaching Resources

Agricultural waste is produced in large amounts worldwide. These are often discarded despite being valuable sources of cellulose and renewable, biodegradable products. At the same time, rising environmental concerns about petroleum-based plastic packaging have created demand for sustainable alternatives. Introducing K-12 students to biodegradable packaging materials developed from agricultural waste can enhance understanding of sustainability, basic materials science, and circular bioeconomy concepts while encouraging interest in STEM fields. Another concern is the presence of microplastics and nanoplastics in drinking water, which can pose serious risks to human health. Traditional coagulation agents, such as ferric and aluminum salts, are less effective …

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Monte Carlo Analysis Of Dose Distribution In Tumour And Adjacent Healthy Tissues During 192Ir Hdr Brachytherapy In The Presence Of Gold Nanoparticles, Damian P. Tippe, Innocent J. Lugendo Jun 2026

Monte Carlo Analysis Of Dose Distribution In Tumour And Adjacent Healthy Tissues During 192Ir Hdr Brachytherapy In The Presence Of Gold Nanoparticles, Damian P. Tippe, Innocent J. Lugendo

Tanzania Journal of Science

High dose rate (HDR) brachytherapy using 192Ir is an effective modality for cancer treatment; however, its therapeutic efficiency is often constrained by unintended radiation exposure to healthy tissues surrounding the tumour. Fortunately, the incorporation of high atomic number (Z) nanoparticles as radiosensitizers has emerged as a promising strategy to enhance tumour dose while sparing adjacent normal tissues. In this study, the dose distribution in tumour and nearby healthy tissues during 192Ir HDR brachytherapy was investigated in the presence of gold (Au) nanoparticles using Monte Carlo simulations based on the Geant4 toolkit. Radial dose distributions and anisotropy characteristics were analysed …

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Syarat Usia Presiden Dan Wakil Presiden Dalam Perspektif Konstitusi Dan Konstitusionalisme: Makna Dan Kriteria, Ardhes Blandhivay Leuanan, Mei Susanto Jun 2026

Syarat Usia Presiden Dan Wakil Presiden Dalam Perspektif Konstitusi Dan Konstitusionalisme: Makna Dan Kriteria, Ardhes Blandhivay Leuanan, Mei Susanto

Jurnal Konstitusi & Demokrasi

In order to investigate the inconsistent interpretations of the Constitutional Court regarding the age requirements for presidential and vice-presidential candidates, this study will analyze the dynamics of determining age requirements from the perspective of the 1945 Constitution and the principles of constitutionalism. A socio-legal approach is used in the normative research method to analyze the Constitutional Court's decisions in light of the social and political factors that shaped them. According to the results, Constitutional Court Ruling No. 90/PUU-XXI/2023 marks a turning point in the evolution of Indonesian constitutional law. Initially, there was no strict interpretation of the age limits for …

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Reorientasi Kebijakan Pelindungan Anak Terhadap Adiksi Internet Dalam Perspektif Pemenuhan Hak Konstitusional Di Indonesia, I Kadek Agus Aditya Firmantara, Bagus Hermanto Jun 2026

Reorientasi Kebijakan Pelindungan Anak Terhadap Adiksi Internet Dalam Perspektif Pemenuhan Hak Konstitusional Di Indonesia, I Kadek Agus Aditya Firmantara, Bagus Hermanto

Jurnal Konstitusi & Demokrasi

This article examines the paradigm shift in child protection policy in the digital environment through Government Regulation Number 17 of 2025 concerning the Governance of Electronic System Providers for Child Protection (PP TUNAS) from the perspective of fulfilling children's constitutional rights in Indonesia. The study is motivated by the increasing use of the internet by children, which not only exposes them to risks such as harmful content, sexual exploitation, and misuse of personal data, but also creates the risk of internet addiction that may adversely affect children's health, education, and overall development. Despite these concerns, internet addiction has not been …

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Protective Effects Of Yogurt Against Sodium Fluoride-Induced Liver Dysfunction In Rabbits, Rasool Bux, Rehana Buriro, Shamsuddin Bughio, Kashif Ali Malak, Muhammad Aqeel, Fayaz Ali, Ali Raza, Abdul Sallam Jun 2026

Protective Effects Of Yogurt Against Sodium Fluoride-Induced Liver Dysfunction In Rabbits, Rasool Bux, Rehana Buriro, Shamsuddin Bughio, Kashif Ali Malak, Muhammad Aqeel, Fayaz Ali, Ali Raza, Abdul Sallam

Journal of Bioresource Management

Fluoride (F-) is among the most important compounds that can damage hepatic tissue and increase level of ALT, ALP, Bilirubin, GGT, and decreases the albumin. Present study was conducted to explore protective role of yogurt on hepatic dysfunction induced by sodium F- at different doses. Animal were divided into seven experimental groups (6 rabbits/group). Group A (Control), Group B (F- 50 mg/kg), Group C (yogurt 15 g/kg), Group D (F- 50 mg + yogurt 15 g/kg), Group E (F- 100 mg/kg), Group F (yogurt 30 g/kg), Group G (F- 100 mg/kg B.W. + yogurt 30 g/kg). In F- treatment groups …

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The Multifaceted Medicinal Properties Of Momordica Charantia: Insights Into Phytochemistry And Therapeutic Applications, Maham Ashfaq, Haroon Ur Rashid, Javaria Ashfaq, Shazia Ramzan, Fatma Hussain Jun 2026

The Multifaceted Medicinal Properties Of Momordica Charantia: Insights Into Phytochemistry And Therapeutic Applications, Maham Ashfaq, Haroon Ur Rashid, Javaria Ashfaq, Shazia Ramzan, Fatma Hussain

Journal of Bioresource Management

Momordica charantia (bitter melon) is a significant medicinal plant, having been long used in traditional medicine in Asian, African and South American systems. M. charantia is more than a traditional medicine; by consolidating existing evidence, it is a promising source of drug discovery and can serve as a complementary in contemporary therapeutics. Over the last several decades, it has become the subject of contemporary biomedical studies due to its abundance of phytochemicals, such as saponins, flavonoids, alkaloids, and polypeptides. These bioactive compounds present a wide range of pharmacological processes that M. charantia can be a natural solution to some of …

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A Mathematical Model For Managing Diphtheria Outbreaks In Nigeria Via Vaccination, Enhanced Surveillance, Effective Quarantine, And Social Distancing Measures, Hycienth Ortser Orapine, Nyiutya Cephas Ine, Dekera Jacob Washachi, Ali Audu Baidu, Lubem Matthew Kwaghkor Jun 2026

A Mathematical Model For Managing Diphtheria Outbreaks In Nigeria Via Vaccination, Enhanced Surveillance, Effective Quarantine, And Social Distancing Measures, Hycienth Ortser Orapine, Nyiutya Cephas Ine, Dekera Jacob Washachi, Ali Audu Baidu, Lubem Matthew Kwaghkor

Mathematical Modelling and Numerical Simulation with Applications

Diphtheria is a highly infectious respiratory and skin disease that poses a significant threat to global public health. In Nigeria, children and adults with low immunity remain at high risk due to recurring annual outbreaks in the last decade, with a death rate of as high as 68.8\%. This paper presents a deterministic compartmental model to evaluate the effectiveness of interventions implemented by the Nigerian government. The model's mathematical and epidemiological validity is established through proofs of non-negativity and boundedness. The basic reproduction number ($R_0$) is derived, and stability analysis confirms that the diphtheria-free equilibrium is locally and globally asymptotically …

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Ai-Enhanced Heat Transfer Optimization In Magnetic Bio-Nanofluids, Hasan Attyah Shaboot Jun 2026

Ai-Enhanced Heat Transfer Optimization In Magnetic Bio-Nanofluids, Hasan Attyah Shaboot

Al-Esraa University College Journal for Engineering Sciences

This study presents a hybrid Artificial Intelligence–Computational Fluid Dynamics (AI-CFD) framework for optimizing heat transfer in magnetic bio-nanofluids subjected to external magnetic fields. Magnetic bio-nanofluids, composed of biocompatible base fluids containing superparamagnetic nanoparticles, exhibit tunable thermal and flow behavior, making them promising for biomedical and micro-cooling applications. Conventional optimization methods based on experiments or brute-force CFD are computationally expensive and limited in exploring the full design space. To overcome these challenges, an Artificial Neural Network (ANN) surrogate model was developed to predict two key performance indicators, the Nusselt number and the friction factor, with high accuracy (R2 > 0.997). The …

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Association Between Body Mass Index, Vitamin D3 And Lipid Profile In Type 2 Diabetes Mellitus, Eman Ali Hussein, Hulia Kanan Mohammed, Zainab Abduljabbar Ridha Al-Ali, Qater Alnada Jassim Mohammed, Alaa Al-Noori, Tarik Muhammad Ali, Noor Thair Tahir Jun 2026

Association Between Body Mass Index, Vitamin D3 And Lipid Profile In Type 2 Diabetes Mellitus, Eman Ali Hussein, Hulia Kanan Mohammed, Zainab Abduljabbar Ridha Al-Ali, Qater Alnada Jassim Mohammed, Alaa Al-Noori, Tarik Muhammad Ali, Noor Thair Tahir

Al-Esraa University College Journal for Medical Sciences

Dyslipidemia and vitamin D Deficiency are one of the most common disorders among type 2 DM patients, this study was conducted to investigate in the relationship between lipid profile and vitamin D status and body mass index (BMI) Among DM patients in Baghdad province / Iraq. study was madeon 120 subjects (diabetic as well non diabetic). The fasting blood glucose (FBG) levels, glycated HbA1c), lipid profile including total cholesterol, triglycerides, LDL, HDL andVLDL levels and serum vitamin D level were analyzed. Current study observied that the values for FBG, HbA1c, insulin, HOMOIR, TC, TG, HDL, LDL, VLDL, and Vitamin D, …

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Effect Of High Protein Diets On Kidney Health Among Athletes And Bodybuilders With Normal Kidney Function, Mustafa Mehdi Alqazzaz, Sajad Abdullah Jleep, Nouran Hussein Mutlaq, Ali Jabbar Jassem Jun 2026

Effect Of High Protein Diets On Kidney Health Among Athletes And Bodybuilders With Normal Kidney Function, Mustafa Mehdi Alqazzaz, Sajad Abdullah Jleep, Nouran Hussein Mutlaq, Ali Jabbar Jassem

Al-Esraa University College Journal for Medical Sciences

This study emphasizes the effect of high-protein diets(HPD) on kidney function, focusing on key biomarkers (Albumin, Urea, Creatinine & GFR). A HPD is defined as a protein consumption >1.5g/kg per day. Results indicated variations in certain biomarkers among the participants (healthy athletes & bodybuilders with normal kidney function) suggesting potential changes in renal workload. Many studies in resistance-trained athletes focusing at HPD, concluded that there are no harmful effects of HPD on renal health. While no immediate kidney damage was observed, we suggest further investigation into the long -term implications of HPD, particularly for individuals with specific health conditions.

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Epidemiology, Classification, Risk Factors, Pathophysiology And Management Of Diabetes Mellitus: A Review, Mohammed Raad Khalaf, Tariq Muhammed Ali, Entedhar K. Hussain, Alaa Al-Noori Jun 2026

Epidemiology, Classification, Risk Factors, Pathophysiology And Management Of Diabetes Mellitus: A Review, Mohammed Raad Khalaf, Tariq Muhammed Ali, Entedhar K. Hussain, Alaa Al-Noori

Al-Esraa University College Journal for Medical Sciences

Diabetes mellitus is a common metabolic disorder, remains a global health challenge with escalating prevalence rates, necessitating a thorough understanding of its multifaceted aspects for effective management. This review synthesizes current knowledge on the epidemiology, classification, risk factors, pathophysiology, and management strategies of diabetes. The epidemiology highlights the rising global prevalence of DM and its regional variations, emphasizing the socio-economic and demographic factors contributing to this epidemic. The classification provides an in-depth analysis of the evolving classification systems, encompassing Type 1, Type 2, and gestational diabetes. Risk factors associated with the development of diabetes are explored, encompassing genetic predisposition, lifestyle …

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The Pivotal Role Of Artificial Intelligence In Optimizing Pharmaceutical Formulation And Delivery, Ali Khidher Abbas, Mustafa M. Noori, Ibtihal Abdulkadhim Dakhil, Mohammed Hussain Al-Mayahy Jun 2026

The Pivotal Role Of Artificial Intelligence In Optimizing Pharmaceutical Formulation And Delivery, Ali Khidher Abbas, Mustafa M. Noori, Ibtihal Abdulkadhim Dakhil, Mohammed Hussain Al-Mayahy

Al-Esraa University College Journal for Medical Sciences

Artificial intelligence (AI) has emerged as a transformative technological paradigm within the pharmaceutical sciences, offering innovative and forward-looking solutions to surmount the inherent limitations associated with conventional drug development, formulation design, and therapeutic delivery systems. Traditional pharmaceutical methodologies frequently entail protracted development timelines, extensive experimental procedures, and substantial financial expenditures, particularly within the domains of formulation optimization and drug delivery design. The integration of AI-driven technologies – encompassing machine learning (ML), deep learning (DL), artificial neural networks (ANNs), and predictive analytics – has considerably accelerated pharmaceutical research by refining decision-making processes, alleviating experimental burden, and enhancing formulation efficiency. The present …

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The Pathological Interaction Between Diabetes And Hypertension: Mechanisms And Clinical Complications, Alaa Al-Noori, Ayad Ahmed Al-Taweel, Qater Alnada Jassim Mohammed, Tarik Muhammad Ali, Majeed Mihsin B. Al-Hamdani, Noor Thair Tahir Jun 2026

The Pathological Interaction Between Diabetes And Hypertension: Mechanisms And Clinical Complications, Alaa Al-Noori, Ayad Ahmed Al-Taweel, Qater Alnada Jassim Mohammed, Tarik Muhammad Ali, Majeed Mihsin B. Al-Hamdani, Noor Thair Tahir

Al-Esraa University College Journal for Medical Sciences

Among the most prevalent chronic conditions, diabetes and hypertension frequently coexist in a single patient, aggravating vascular problems and hastening the deterioration of target organs, especially the kidneys. By raising intraglomerular pressure, impairing endothelial function, and triggering oxidative stress and inflammation, hypertension directly increases the chance of developing diabetes sequelae, including diabetic nephropathy. Chronic kidney disease advances more quickly when poorly managed hyperglycemia and hypertension combine to cause a decrease in glomerular filtration rate and an increase in urine albumin excretion. Other consequences like retinopathy, neuropathy, and cardiovascular disease are also encouraged by this pathological occurrence. Reducing the advancement of …

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Clinical Significance Of Liver Enzyme Biomarkers In Chronic Statin Users, Muayad Khaleel Ibrahim, Saad Mahmoud Saeed Jun 2026

Clinical Significance Of Liver Enzyme Biomarkers In Chronic Statin Users, Muayad Khaleel Ibrahim, Saad Mahmoud Saeed

Al-Esraa University College Journal for Medical Sciences

It is possible that statins, by their dual capacity to modulate (both stimulate and suppress) immune responses, could play a role in influencing the course of autoimmune diseases. Consequently, our investigation was designed to explore how statins impact both the innate and adaptive branches of the immune system, as well as their effect on the crucial mechanism of self-tolerance. This was achieved through the comprehensive measurement of various antibody profiles, specifically including the detection and quantification of autoantibodies, such as antinuclear antibodies and Creatinine kinase, Aldolase, HMGCR antibody, Albumin and Bilirubin and Alanine transaminase, Aspartate aminotransferase, Our investigation employed a …

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Measuring The Concentration Of Heavy Metals In The Serum Of Traffic Police And Their Impact On Heart Disease In The Future, Hanaa Khalil Sacheat Jun 2026

Measuring The Concentration Of Heavy Metals In The Serum Of Traffic Police And Their Impact On Heart Disease In The Future, Hanaa Khalil Sacheat

Al-Esraa University College Journal for Medical Sciences

The spread of heavy metals such as lead, cadmium and nickel is a clear danger that threatens the earth and disrupts the ecological balance. In this research, we evaluated the danger of these metals present in the areas of traffic points for traffic policemen who are present for long periods at traffic points. 25 blood samples were collected from traffic policemen present at traffic points, with information about age, date of joining the job, and smoking, The comparison was made with the same number of samples of people who were in a job inside buildings, The results showed a significant …

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Dynamical Behavior, Extinction And Persistence In A Stochastic Delayed Two-Strain Epidemic Model With A Generalized Crowley-Martin Incidence Rate, Amina Allali, Dounia Bentaleb, Saida Amine Jun 2026

Dynamical Behavior, Extinction And Persistence In A Stochastic Delayed Two-Strain Epidemic Model With A Generalized Crowley-Martin Incidence Rate, Amina Allali, Dounia Bentaleb, Saida Amine

Mathematical Modelling and Numerical Simulation with Applications

This paper develops and analyzes a novel delayed stochastic SIR epidemic model with two interacting strains and general incidence functions. By establishing the existence and uniqueness of a positive global solution, the well-posedness of the model under stochastic perturbations is ensured. Extinction occurs when the stochastic reproduction number falls below unity, as demonstrated through Itô calculus and martingale convergence theorems, while persistence is guaranteed under the Crowley–Martin incidence when it exceeds one. Numerical experiments based on the Positive Preserving Truncated Euler–Maruyama (PPTEM) scheme confirm the analytical predictions and highlight the influence of time delay and noise intensity on the long-term …

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Tumor–Immune Dynamics With Memory And Time Delay: A Fractional-Order Model With Ctla-4 Regulation, Mutaz Mohammad, Mohyeedden Sweidan, Alexander Trounev, Fathalla Rihan Jun 2026

Tumor–Immune Dynamics With Memory And Time Delay: A Fractional-Order Model With Ctla-4 Regulation, Mutaz Mohammad, Mohyeedden Sweidan, Alexander Trounev, Fathalla Rihan

Mathematical Modelling and Numerical Simulation with Applications

This study develops a fractional-order tumor-immune interaction model incorporating Caputo memory effects, delayed immune activation, and CTLA-4 checkpoint regulation. The model describes the coupled dynamics of tumor cells, CD4$^{+}$ T cells, IFN-$\gamma$, and CTLA-4, and extends classical integer-order tumor-immune models by accounting for hereditary immune responses and biologically motivated latency effects. Theoretical properties, including positivity, boundedness, equilibrium structure, and fractional-order stability, are examined to establish the biological and mathematical consistency of the model. The delayed fractional system is then investigated computationally by comparing several numerical methods, including finite difference discretization, Daubechies wavelet collocation, Euler wavelet collocation, and a predictor-corrector scheme. …

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Numerical Method For Strongly Variable-Density Flows At Low Mach Number: Flame-Sheet Regularisation And A Mass-Flux Immersed Boundary Method, Matheus P. Severino, Fernando F. Fachini, Elmer M. Gennaro, Daniel Rodríguez, Leandro F. Souza Jun 2026

Numerical Method For Strongly Variable-Density Flows At Low Mach Number: Flame-Sheet Regularisation And A Mass-Flux Immersed Boundary Method, Matheus P. Severino, Fernando F. Fachini, Elmer M. Gennaro, Daniel Rodríguez, Leandro F. Souza

Mathematical Modelling and Numerical Simulation with Applications

A low-Mach-number flow, in the laminar regime, has intrinsically two characteristic spatial scales for a given time scale, or two characteristic temporal scales for a given spatial scale, and these dual scales are very different due to the disparity between the flow and acoustic speed. Therefore, low-Mach-number flows impose mathematical and computational challenges in their description. Standard numerical methods for compressible flows, which are typically designed for problems with a single dominant spatial and temporal scale, require alternative approaches, such as preconditioning techniques or solvers tailored for low-Mach-number equations. The present work introduces a simplified fluid dynamics model for flows …

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Usa V. Zachary Williams Jun 2026

Usa V. Zachary Williams

2026 Decisions

USDC for the District of New Jersey

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Crispr/Cas9-Based Genome Editing: Understanding Differences In Dna Repair Pathways, Profiles, And Outcomes, Samuel Effah, Shirley Barrera, Nahia Urturi Ortiz, Will Dampier, Michael Nonnemacher, Brian Wigdahl Jun 2026

Crispr/Cas9-Based Genome Editing: Understanding Differences In Dna Repair Pathways, Profiles, And Outcomes, Samuel Effah, Shirley Barrera, Nahia Urturi Ortiz, Will Dampier, Michael Nonnemacher, Brian Wigdahl

Kimmel Cancer Center Faculty Papers

Over a decade of advances in Clustered Regularly Interspersed Short Palindromic Repeats (CRISPR) and CRISPR-associated protein 9 (Cas9)-based technologies have culminated in the first-ever FDA-approved CRISPR/Cas-based therapy. Aside from this approved therapy for sickle cell anemia, several CRISPR/Cas-based therapies are currently under development or testing for a range of chronic diseases, including viral diseases like human immunodeficiency virus type 1 (HIV-1) infection, genetic diseases like familial hypercholesterolemia, and cancer. The success of these therapies hinges on the effective delivery of CRISPR/Cas9 components to target regions, efficient Cas endonuclease editing, repair profiles generated, and their resulting outcomes. Here, we discuss the …

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Evaluation Of A Vortex Flow Device On A Center Pivot Irrigation System, Ankit Chandra, Derek M. Heeren, Tyler Smith Jun 2026

Evaluation Of A Vortex Flow Device On A Center Pivot Irrigation System, Ankit Chandra, Derek M. Heeren, Tyler Smith

Department of Agricultural and Biological Systems Engineering: Presentations and White Papers

This study presents the first independent field evaluation of a passive vortex flow device designed to reduce hydraulic friction in pressurized irrigation systems. Experiments were conducted on a full-scale, groundwater-fed center pivot irrigation system at the Eastern Nebraska Research, Extension, and Education Center (ENREEC). A paired comparison approach was used to quantify differences in flow rate, energy consumption, and pressure distribution along the pivot lateral under baseline (no device) and treatment (device installed) conditions. Results showed negligible change in system flow rate (621 vs. 618 gpm) and energy consumption (~1.2% difference), consistent with expectations for pressure-regulated irrigation systems. However, the …

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Psoriasis Effects On Psychological And Daily Activities In Patients Attending To Outpatient Clinics In Aldiwaniyah Teaching Hospital, Saja Abbas Musa, Hassan Raji Jallab, Akeel Hamid Jabur Jun 2026

Psoriasis Effects On Psychological And Daily Activities In Patients Attending To Outpatient Clinics In Aldiwaniyah Teaching Hospital, Saja Abbas Musa, Hassan Raji Jallab, Akeel Hamid Jabur

Al-Qadisiyah Medical Journal

Background: Psoriasis is a chronic immune-related skin disorder affecting 2–3% globally, linked to heart disease, joint issues, metabolic syndrome, and psychological disorders. It also impacts social life, mental health, and work productivity, with added challenges in Middle Eastern patients due to stigma and limited healthcare access. Aim: To assess the psychological and functional impact of psoriasis on patients attending Al-Diwaniyah Teaching Hospital. It focuses on anxiety, depression, social disengagement, and effects on daily activities like work, exercise, sleep, and hygiene. The study also explores the relationship between disease severity and impairment levels. Material and Methods: The study was conducted at …

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Correlation Of Norepinephrine With Some Biochemical Parametric In Patients With Type 2 Diabetes Mellitus, Aqeel Abed Nour Hadi, Ferdous A. Jabir, Muhammad Abd-Alwahab Jun 2026

Correlation Of Norepinephrine With Some Biochemical Parametric In Patients With Type 2 Diabetes Mellitus, Aqeel Abed Nour Hadi, Ferdous A. Jabir, Muhammad Abd-Alwahab

Al-Qadisiyah Medical Journal

Background: Type 2 diabetes is a chronic metabolic disorder characterized by high blood sugar levels (hyperglycemia) resulting from the body's reduced ability to produce or use insulin effectively. Insulin is a hormone that regulates blood sugar levels, and in type 2 diabetes, the body either does not produce enough insulin or becomes resistant to its effects. This causes a buildup of glucose in the bloodstream, which can eventually harm organs and tissues. This study was carried out on patients who attended the Diabetes and Endocrinology Specialist Center of Marjan City for Medical Education in Babil Province; all patients were diagnosed …

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Limited Predictive Value Of Vaginal Discharge And Cervical Ectropion For Chlamydia Trachomatis Infection Detected By Direct Immunofluorescence, Dian Novitasari, Willy Sandhika, Ashon Sa'adi, Lusiani Tjandra Jun 2026

Limited Predictive Value Of Vaginal Discharge And Cervical Ectropion For Chlamydia Trachomatis Infection Detected By Direct Immunofluorescence, Dian Novitasari, Willy Sandhika, Ashon Sa'adi, Lusiani Tjandra

Folia Medica Indonesiana

Chlamydia trachomatis is one of the most common sexually transmitted infections, often asymptomatic, yet a major cause of infertility. In clinical practice, vaginal discharge and cervical ectropion are frequently used as syndromic indicators. However, their predictive value for Chlamydia trachomatis infection remains limited, particularly in regions with restricted access to NAAT/PCR, such as Indonesia. This study aimed to evaluate the diagnostic value of vaginal discharge and cervical ectropion as predictors of Chlamydia trachomatis infection using the Direct Immunofluorescence (DIF) method. This study used a cross-sectional design conducted among 93 reproductive-aged women from coastal areas of Jember, East Java, Indonesia, who …

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Prognostic Factors Related To Histopathological Diagnosis Of Soft Tissue Sarcoma: Meta-Analysis, Rani Ahmad Jun 2026

Prognostic Factors Related To Histopathological Diagnosis Of Soft Tissue Sarcoma: Meta-Analysis, Rani Ahmad

Journal of King Abdulaziz University: Medical Sciences

Background: With the heterogeneity of soft tissue sarcoma (STS) and the significant impact of histological subtype on treatment planning, there is a critical need for robust predictive for strong predictive factors. Treatment options for tumors vary by stage, grade, type, and location, reflecting the significant heterogeneity of STS.
Objectives: The objective of this study was to systematically evaluate and quantitatively synthesize the available evidence regarding the prognostic significance of clinico-pathological factors in patients with soft tissue sarcomas (STS).
Methods: A systematic review and meta-analysis were conducted to assess overall survival among STS patients between 2010 and 2023. Ten studies were …

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Metabolomic Associations Of Atorvastatin In Human Blood, Ahmed M. Alsehli Jun 2026

Metabolomic Associations Of Atorvastatin In Human Blood, Ahmed M. Alsehli

Journal of King Abdulaziz University: Medical Sciences

Atorvastatin is one of the most widely prescribed lipid-lowering therapies worldwide. Although its cholesterol-lowering effects are well established, the broader systemic metabolic signatures associated with atorvastatin exposure across large human populations remain incompletely characterized. We performed a retrospective metabolomic meta-analysis of human blood samples from approximately 4,000 individuals across six cohorts to identify metabolites most positively and negatively associated with atorvastatin levels. Circulating metabolites spanning both lipid and non-lipid classes were identified as associated with blood atorvastatin levels. Atorvastatin levels were associated with a distinct blood metabolomic signature comprising coordinated changes across multiple metabolite classes. Negatively associated metabolites were dominated …

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Comprehensive Prediction Analysis Of Novel Noncoding Regulatory Variants Identified In The Microrna Binding Regions In Complement System Genes, Anthony Shadid, Haydn E Rich, Kathryn D Hok, Marie-Francoise Doursout, Marcos I Restrepo, Nirmal K Banda, Lavanya Gunamalai, Pooja Shivshankar Jun 2026

Comprehensive Prediction Analysis Of Novel Noncoding Regulatory Variants Identified In The Microrna Binding Regions In Complement System Genes, Anthony Shadid, Haydn E Rich, Kathryn D Hok, Marie-Francoise Doursout, Marcos I Restrepo, Nirmal K Banda, Lavanya Gunamalai, Pooja Shivshankar

The Brown Foundation: Institute of Molecular Medicine

The complement system is a central component of innate immunity that coordinates host defense, immune surveillance, and inflammatory responses through tightly regulated proteolytic cascades. Genetic variation within complement genes contributes substantially to interindividual differences in complement activity and disease susceptibility. While coding variants directly alter complement protein structure and function, the microRNA (miRNA)-mediated control and post-transcriptional regulation is not fully understood in shaping complement gene expression across immune and inflammatory mechanisms. Complement pathway genes exhibit extensive and heterogeneous 3'-untranslated regions (3'UTRs), which serve as primary platforms for miRNA binding and RNA-binding protein interactions. Both common and rare single-nucleotide polymorphisms within …

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Essential And Non-Essential Amino Acid Composition Of Hilsa (Tenualosa Ilisha) Fish In Different Fishing Regions Of Bangladesh, Mohajira Begum, Md. Moshfekus Saleh-E-In, Md. Zia Uddin Al Mamun, Umma Fatema Shahjadee, Farha Matin Juliana, Md. Sabir Hossain Jun 2026

Essential And Non-Essential Amino Acid Composition Of Hilsa (Tenualosa Ilisha) Fish In Different Fishing Regions Of Bangladesh, Mohajira Begum, Md. Moshfekus Saleh-E-In, Md. Zia Uddin Al Mamun, Umma Fatema Shahjadee, Farha Matin Juliana, Md. Sabir Hossain

Journal of King Abdulaziz University: Marine Science

Hilsa, Tenualosa ilisha (Hamilton, 1822), is one of the favourite and popular tropical fish in the people of South-East Asia due to its delicious taste and flavour. This study investigates the comprehensive amino acid profiles of various fishing locations of Bangladesh to assess the protein quality and nutritional values. Fourteen free amino acids were identified from the six riverine locations of Bangladesh. The total free amino acid (TAA) contents were ranged from 11.60 g/100 g in Cox's Bazar to 13,40 g/100 g in Kirtonkhola for raw fish. In the case of smoked treated, the TAA ranged from 14.01 g/100 g …

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Operational Risk Assessment Of Ship To Shore Petroleum Transfer Using Fuzzy Rule-Based Bayesian Networks, Ayman F. Alghanmi Jun 2026

Operational Risk Assessment Of Ship To Shore Petroleum Transfer Using Fuzzy Rule-Based Bayesian Networks, Ayman F. Alghanmi

Journal of King Abdulaziz University: Marine Science

Petroleum ports represent critical infrastructure in global energy supply chains, where operational risks during ship-to-shore transfer operations can lead to catastrophic consequences including environmental damage and human casualties. Despite rigorous safety protocols, these facilities remain vulnerable to operational hazards in dynamic maritime environments. This research aimed to develop and apply a hybrid Fuzzy Rule-Based Bayesian Reasoning (FRBBR) model to identify, evaluate, and prioritize operational hazards during crude oil transfer operations at petroleum port berths, with a case study conducted in Saudi Arabia, addressing the challenge of risk assessment where historical data is limited.
The research employed a mixed-methods approach combining …

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