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Unveiling The Diversity Within Salvia Caespitosa Sensu Lato (Lamiaceae): Three New “Hidden” Endemic Species From Türkiye​, Ferhat Celep, Musa Doğan, Gali̇p Akaydin, Ahmet Kahraman, Ersi̇n Karabacak, Ömer Çeçen, Meti̇n Armağan, Chun-Lei Xiang, Bryan T. Drew

Turkish Journal of Botany

Documenting species, particularly those that are threatened or endangered, is fundamental to biodiversity conservation. However, many taxa remain scientifically unrecognized, being either undiscovered or unpublished. While some plants can be easily recognized as new species, other identifications are obscured by morphological, taxonomic, and nomenclatural complexity. Detecting cryptic or “hidden” species is therefore essential to understanding biodiversity and plant evolution. Our revisionary studies on Salvia demonstrate that the morphologically complex Salvia caespitosa is not a single species but instead comprises at least four distinct species, three with narrow distributions. This conclusion is supported by integrative evidence from extensive field studies, herbarium …

Cnkg: Harnessing Large Language Models For Cognitive Neuroscience Knowledge Graph Construction, Ali Sarabadani, Kheirollah Rahsepar Fard, Hamid Dalvand

Turkish Journal of Electrical Engineering and Computer Sciences

Textual resources are among the most valuable sources of information in cognitive neuroscience (CN) for understanding and investigating brain activity and cognitive processes. Extracting and constructing knowledge graphs (KGs) from these texts can facilitate medical research by providing deeper insights into neurological diseases and brain function. In recent years, the use of large language models (LLMs) in natural language processing (NLP) has become increasingly widespread, significantly enhancing the extraction of meaningful information from large volumes of text. This study proposes a novel approach for constructing and evaluating a specialized knowledge graph, termed the cognitive neuroscience knowledge graph (CNKG), from scientific …

Distributed Impressions: How Multiple Minds Come Together To Shape Person Perception, Lindsey J. Tepfer

Dartmouth College Ph.D Dissertations

Moments after perceiving another person, we immediately infer a wealth of information about them. Despite the complexities within our social environments, we distill an incredible magnitude of details available to us into compressed representations of other people’s minds and mannerisms. Yet research has focused largely on mapping isolated stimuli—divorced from its messy context—to the spontaneous impressions they provoke. As a result, there are many unanswered questions about how our judgments are influenced by the rich and noisy social world we inhabit. Here, I’ve leveraged two paradigms to investigate how impression formation and updating may operate when the constraints of the …

Mxene-Based Optical Fiber Sensors For Chemical And Biosensing: Review And Perspectives, Chen Zhu, Huaijun Guan, Chenxi Huang, Rex E. Gerald, Jie Huang

Electrical and Computer Engineering Faculty Research & Creative Works

No abstract provided.

Combining Menin And Mek Inhibition To Target Poor Prognosis Kmt2a-Rearranged Ras Pathway-Mutant Acute Myeloid Leukemia., Nastassja Scheidegger, Constanze Schneider, Gabriela Alexe, Yi-Cheng Wang, Todd A. Alonzo, Allen Basanthakumar, Wallace A. Bourgeois, Julia Dudkiewicz-Garbicz, Delan Khalid, Lucy A. Merickel, Jennifer A. Perry, Rhonda E. Ries, Silvi Salhotra, Audrey Taillon, Alan S. Gamis, Richard Aplenc, Marian H. Harris, Mark Wunderlich, Scott A. Armstrong, Jessica A. Pollard, Soheil Meshinchi, Yana Pikman, Kimberly Stegmaier

Manuscripts, Articles, Book Chapters and Other Papers

KMT2A-rearranged (KMT2A-r) acute leukemias are especially prevalent in the pediatric population. KMT2A-fusion proteins drive leukemogenic gene expression through an interaction with a chromatin complex that includes the scaffold protein menin, giving rise to aggressive acute leukemias. RAS pathway mutations are also common in pediatric leukemia. In a cohort of 1750 patients enrolled on Children's Oncology Group (COG) trials, we identified RAS pathway mutations in 43% of acute myeloid leukemia (AML) cases. The presence of RAS pathway mutations in KMT2A-r AML was associated with a lower complete remission rate, poor event-free survival and overall survival (OS), and early relapses. Given the …

Evaluation Of Cytotoxic Effect From Clinacanthus Nutans Leaf Extract On Mda-Mb231 Cells Expressing Cd44+/Cd24–, Siti Syarifah, Tri Widyawati, Sri Melinda Kaban, Nor Adlin Md Yusoff

Baghdad Science Journal

Breast cancer prevalence and incidence are increasing globally every year. Medication resistance and recurrence are more likely in breast cancer cells that express CD44⁺/CD24^–. C.nutans leaves are a traditional medicinal herb with numerous pharmacological benefits, including antioxidant and antiproliferation properties, although the activity against breast cancer stem cells is still unclear. Method: In this study, C.nutans leaves were extracted using ethanol solvent with graded concentrations of 100%, 80%, 60%, 40%, 20%, and 0% (water), respectively, by maceration. We used isolated MDA-MB231 cells with high expression of CD44⁺/CD24^– by using magnetic-activated cell sorting …

Study Of The Correlation Between Asprosin And Insulin Resistance In Obese And Normal-Weight Pcos Patients, Walaa Najm Abdulwahid, Reem M. Obaid

Baghdad Science Journal

Fatty tissue is considered an endocrine organ that produces a type of hormone called Adipokine; this hormone is specifically secreted by adipose tissues, such as asprosin. Polycystic Ovarian Syndrome (PCOS) is the most common hormonal condition throughout the years of reproduction in females, manifesting with a significant frequency of decreased glucose tolerance, increased serum androgen levels, and type 2 diabetes among female sufferers who are overweight or obese. The current investigation included 120 PCOS patients (40 obese, 40 normal weight) and 40 healthy women; samples were collected from July to December 2024 at Kamal al-Samarrai Hospital in Baghdad, Iraq. Serum …

Histopathological And Immunological Effects Of Tamanu Oil Nanoemulsion On Imiquimod Induced Psoriasis In Albino Rat Skin, Israa Mahmood Mohammed, Treefa Farouq Ismail

Baghdad Science Journal

Psoriasis is an autoimmune disease caused by T-cell activation. This condition is characterized by skin proliferation and inflammation. This study aimed to enhance tamanu oil bioavailability by green synthesis method, in order to evaluate the potential anti-psoriatic benefits of tamanu oil nanoemulsion in rat skin, based on observational, histopathological, and immunological outcomes. The formulation was prepared by phase inversion temperature technique. The physical and chemical characteristics include: droplet morphology, size, zeta potential, pH, and stability. The formulation exhibited a spherical and small globule size of less than 100 nm, good zeta potential (–23.9 mV), suitable pH (5.3) and physically stable. …

Cytokine Profiles In Rheumatoid Arthritis: Relationship Of Tnf-Α , Il-17, And Il-13 With Autoantibodies (Rf And Anti-Ccp) And Clinical Disease Severity, Sonia Elia Ishaq, Taban Kamal Rasheed, Niaz Albarzingi

Baghdad Science Journal

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and autoantibody production. This study aimed to assess serum levels of TNF-α , IL-17, and IL-13 in RA patients and to explore their association with disease severity and autoantibody status in comparison to healthy controls. The study involved 67 RA patients and 20 healthy individuals. Patients were initially classified based on autoantibody status (RF-positive vs. RF-negative and anti-CCP-positive vs. anti-CCP-negative), and further categorized into low, moderate, and high disease activity groups. Cytokine levels were measured by ELISA, CRP and RF by turbidimetry, and anti-CCP levels by electrochemiluminescence immunoassay. …

Foliar Application Of Methyl Jasmonate And Titanium Nanoparticles Mitigates The Negative Effects Of Salinity On Lettuce Plants, Tahani J. Hijazin

Baghdad Science Journal

Salinity stress is one of the major abiotic factors that significantly impact plant growth. In this regard, this work investigated a way to alleviate the adverse impacts by simultaneously spraying methyl jasmonate and titanium nanoparticles on lettuce (Lactuca sativa L.) plants, which are grown under induced salinity conditions. Two concentrations of salt (100 and 150 mM NaCl) were applied to the plants. After that, simultaneous spraying of methyl jasmonate (0.5 and 1 mM) and titanium nanoparticles (100 and 200 mg/L) was performed on lettuce leaves. Following the application of the previous treatments, the plants were collected, and various …

Effects Of Modified Cryoprotectants On The Expression Of Heat Shock Protein 90 (Hsp90) And Zona Pellucida Ii (Zpii) Of Post-Thawing Sperm Quality, Silvia Werdhy Lestari, Manggiasih Dwiayu Larasati, Gita Pratama, Mulyoto Pangestu, Muhammad Thoriq, Dantha Rafael Sitompul

Baghdad Science Journal

Sperm cryopreservation is a basic element of assisted reproductive technology, yet it often compromises cell viability through thermal and osmotic stress. The cellular response involves HSP90, a stress marker and ZPII, which is essential for sperm-oocyte interaction and preventing polyspermy. In addition, this modified cryoprotectant combines glycerol and raffinose is expected to reduce damage and increase spermatozoa's recovery rate after cryopreservation. To address these challenges, we investigated the expression levels of HSP90 and ZPII to assess the protective capacity of modified cryoprotectant formulations. These parameters were analyzed pre- and post-cryopreservation to establish whether these novel mediums superiorly preserve sperm integrity …

Influence Of A New Nanoensemble Of Graphene Oxide And Indole-3-Acetic Acid On The Morphophysiological, Biochemical, And Ultrastructural Characteristics Of Upland Cotton (Gossypium Hirsutum L.), Nurlan Amrahov, Ulviyya Hasanova, Aliyeva Gunel, Aghazada Goncha, Fuad Rzayev, Eldar Gasimov, Aliyeva Solmaz, Lala Gahramanli, Elvin Ibrahimli, Ruhangiz Mammadova, Zarema Gakhramanova, Cem Bayram, Goncha Eyvazova, Si̇bel Hasanova, Ziyaddin Mammadov

Turkish Journal of Botany

​The exogenous application of phytohormones plays a crucial role in the activation of adaptive mechanisms in plants under both normal and stress conditions. Therefore, the present study investigates the synthesis, characterization, and application of nanoensembles based on indole-3-acetic acid (IAA) and graphene oxide (GO) nanolayers. The surface of GO synthesized by the modified Hummer method was noncovalently functionalized with IAA molecules. The structure and morphological properties of the prepared materials were analyzed by Fourier transform infrared spectroscopy, X-ray diffraction, UV-Vis spectroscopy, and transmission electron microscopy. The IAA and IAA+GO nanoensemble enhanced the morphological parameters, lateral root formation, catalase and peroxidase …

Effects Of Calcium And Magnesium Ions On Wheat (Triticum Aestivum) Chromosome Structure Visualized Using Light And Scanning Elec​Tron Microscopes, Andi Salamah, Fitri Amalia Nurchasanah, Vycka Fikriyani Fairuz, Astari Dwiranti

Turkish Journal of Botany

Divalent cations, particularly calcium (Ca2+) and magnesium (Mg2+), are essential for maintaining chromosomal architecture, yet their roles in plants remain poorly characterized. This study investigated the effects of Ca2+ and Mg2+ on the chromosomal structure of wheat (Triticum aestivum, 2n = 6x = 42), a widely used model in plant cytogenetics. Root-tip chromosomes were isolated enzymatically and treated with BAPTA (a Ca2+-specific chelator), EDTA (a broad cation chelator), and buffer solutions containing either 5 mM Mg2+ (XBE5) or no Mg2+ (XBE). Chromosomes were stained with aceto-orcein for light microscopy and processed for scanning electron microscopy (SEM). Microscopic observations revealed that …

Systematic Implications Of Seed Morphology In Oxytropis (Galegeae: Fabaceae) From Pakistan, Amjad Khan, Amir Sultan, Raees Khan, Rozina Rozina, Shahab Ali, Ali Bagheri, Rifat Ullah Khan, Abdul Samad Mumtaz, Tariq Ullah, Ghalia Saleem Aljeddani, Hasil Khan

Turkish Journal of Botany

Oxytropis is a taxonomically challenging genus within the tribe Galegeae of the family Fabaceae. Despite its systematic importance, the seed morphology of Oxytropis has been poorly investigated. In the present study, we examined the seed morphology of 18 Oxytropis species representing 10 sections from the Pakistan, with the aim of evaluating the diagnostic value of seed traits using both light and scanning electron microscopy. The current investigation revealed two distinct seed shapes, namely cordiform and prolonged reniform, across the studied taxa. Seed length ranged from 1.75 mm in O. crassiuscula to 2.3 mm in O. duthieana, while seed width varied …

A New Species Of The Genus Heracleum From Türkiye: H. Papilionaceum (Apiaceae: Tordyliaea​), Mehmet Sağiroğlu, Mardiya Sabdani̇, Bariş Bani̇, Hayri̇ Duman

Turkish Journal of Botany

A new species, Heracleumpapilionaceum (Apiaceae: Tordylieae), is described and illustrated from the Elmacık Mountains, Bolu Province, northwestern Türkiye. Morphological studies and phylogenetic analyses based on nuclear ribosomal (nr)DNA Internal Transcribed Spacer sequences placed the new species close to H. apiifolium and H. munzurense. Comparative morphological and fruit anatomical data, images, and a distribution map are provided. An International Union for Conservation of Nature Red List assessment is also presented, supporting its classification as Critically Endangered.

Evolutionary Neural Architecture Search: A Survey, Ferda Nur Özçeli̇k, Mehmet Önder Efe

Turkish Journal of Electrical Engineering and Computer Sciences

Deep Neural Networks (DNNs) have achieved remarkable success across diverse machine learning applications, yet designing effective architectures remains a laborious, expert-driven process. Neural Architecture Search (NAS) was introduced to automate this process, with Evolutionary NAS (ENAS) emerging as one of the most effective and widely adopted NAS paradigms. This survey provides a comprehensive and systematic review of 164 ENAS studies published between 2020 and 2024, categorized according to the specific evolutionary algorithm employed as the search strategy. Unlike prior surveys—which either treat evolutionary methods at a high level or focus on general NAS pipelines—this study is, to the best of …

What Are Vestigial Structures? Evidence For Evolution Explained, Ryan Bebej

University Faculty Publications and Creative Works

Evolution wasn’t something we talked about very much in my home or church when I was growing up.

Yet somehow, I came to believe that evolution wasn’t compatible with Christian faith. At the time that seemed okay, because I had heard that the evidence for evolution wasn’t very strong anyway.

That all began to change when I started studying biology in college. In different classes, I encountered some of the compelling evidence for evolution and common descent.

Vestigial structures were one of the topics that came up often in biology textbooks about these topics.

Today, biologists point to …

Dabrafenib-Induced Cutaneous Eruptions In A Patient With Langerhans Cell Histiocytosis, Jaanvi Mehta, Julianna Tolotta, Eleanor Matthews, Daniel Joffe, Safiyyah Bhatti, Lauren Banner, Jenna Mandel, Molly Wallace, Timothy G. Webster, Jason B. Lee, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

Langerhans cell histiocytosis (LCH) is a rare malignancy marked by clonal proliferation of Langerhans cells, with BRAF V600E mutations identified in over 50% of the cases. BRAF inhibitors (BRAFi), such as dabrafenib, have shown efficacy in treating BRAF V600E-mutant LCH. However, BRAFi therapy is associated with cutaneous adverse effects, including the development of new melanocytic nevi, verrucae, and keratinocyte carcinoma (KC). This case report describes a 78-year-old woman with BRAF V600E-mutant LCH who developed multiple dermatologic side effects following dabrafenib salvage therapy. Seven weeks into treatment, the patient presented with eruptive palmoplantar nevi, verrucae, and a basal cell carcinoma (BCC). …

What Works For Dyslexia Training? A Comparative Study Of Three Professional Development Approaches For Elementary General Education Teachers, Kayla Steltenkamp

Kentucky Teacher Education Journal: The Journal of the Teacher Education Division of the Kentucky Council for Exceptional Children

Teachers are the foundational component of the educational system, yet many enter the classroom without adequate knowledge of dyslexia -- a specific learning disability affecting up to 17.5% of the student population. Despite growing legislative mandates requiring teacher training on dyslexia, recent research confirms that misconceptions and knowledge gaps persist among both preservice and inservice teachers, and the question of which professional development models most effectively address those gaps remains largely unanswered. This study compared three two-hour professional development approaches -- simulation only, lecture only, and a mixed-method combining both -- using a quasi-experimental, pre-test/post-test design with 58 elementary general …

Declarative Ai-Persona Lifecycle As Kubernetes Custom Resources With Cognitive-Queue-Driven Autoscaling, Gustavo Matthew Assuncao

Defensive Publications Series

This publication discloses, with enabling detail, a Kubernetes-native control-plane pattern for operating fleets of long-lived, autonomous AI personas as declarative infrastructure. Each persona's cognitive lifecycle — the enablement of its cognitive loop, the interval of that loop, its per-day and per-request token budgets, its granted tool set, and the business domains it may act within — is expressed in the spec of an AIOSPersona Custom Resource. A dedicated operator continuously reconciles observed runtime signals into the resource's status subresource, which carries a five-state lifecycle machine — Dormant → Booting → Active → Dreaming → Suspended — together with two live …

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Tails From The Isle Of Devils: Two New Records Of Non-Native Invasive Scorpions (Arachnida: Scorpiones) Successfully Intercepted In Bermuda, Including The First Record Of Caraboctonidae, Danniella Sherwood, Mark Outerbridge, Struan R. Smith, Jenny Gosling, Myles Darrell

Euscorpius

Hadruroides sp. (Scorpiones: Caraboctonidae) is newly recorded as a successfully intercepted non-native invasive species in Bermuda, based on examination of a desiccated and damaged immature female specimen. A second record of an intercepted Centruroides gracilis (Latreille, 1804) (Scorpiones: Buthidae) is reported based on examination of an adult male.

Chemistry Of Co2 Capture And Storage: From Molecular Interactions To Advanced Functional Materials, Nany Hairunisa, Hazim F. Abbas, Amamer M. Redwan

Al-Mustaqbal Journal of Sustainability in Engineering Sciences

In light of the industrial development taking place, the burning of fossil fuels for transportation and electricity generation, and the accompanying carbon dioxide emissions, there is an urgent and continuing need to innovate methods of capture and storage, as well as competitive materials to address increasing carbon emissions. This review describes the importance of this procedure and the technologies that help solve this problem, some of which have been adopted by many countries and industrial institutions and differ in their efficiency, cost, and applicability.

Effect Of Extraction Methods On Emulsifying Properties Of Corn Fiber Gum, Wu Chenglong, Ren Ying, Li Xingguo, Tang Leiming, Sun Xiaohong

Food and Machinery

[Objective] To investigate the influence of three extraction methods (alkaline, enzymatic, and acidic) on the emulsification characteristics of corn fiber gum (CFG). [Methods] Corn bran was used as the raw material, and CFG was extracted using sodium hydroxide, xylanase, and formic–acetic acid–water solutions. The changes in particle size, zeta potential, rheological properties, creaming index, appearance, and microstructure of CFG emulsions were measured. [Results] All three CFG emulsions exhibited shear-thinning behavior, with viscosities decreasing as the shear rate increased. The enzymatically extracted CFG emulsion had the highest viscosity, best gel properties, smallest particle size [(751.6 ± 22.5) nm], highest absolute zeta …

Quantitative Analysis Of Sorghum Starch Using Machine Learning And Near-Infrared Spectroscopy, Li Ke, Ouyang Runkun, Dai Yijie, Li Jie, Hou Aixiang, Yang Yu, Li Zongjun

Food and Machinery

[Objective] To establish a model for the rapid quantification of sorghum starch based on near-infrared spectroscopy and machine learning algorithms. [Methods] Brewing sorghum was used as the raw material. Near-infrared diffuse reflectance spectra were collected using a near-infrared spectrometer. The Isolation Forest algorithm was employed to remove outlier samples and optimize the dataset. Subsequently, multiple preprocessing methods and regression models were compared using various modeling software to analyze and establish a quantitative model for sorghum starch. [Results] After preprocessing with the Isolation Forest algorithm, the partial least squares regression (PLSR) model exhibited the best performance, with a coefficient of determination …

Extraction Optimization For Polyphenols From Clausena Anisum-Olens Kernel , As Well As Their Antioxidant And Antibacterial Activities, Liao Jianhong, Su Xiufang, Zheng Guangjin, Li Ganghui

Food and Machinery

[Objective] To optimize the extraction process of polyphenols from Clausena anisum-olens kernel, and to analyze their in vitro antioxidant and antibacterial activities. [Methods] With ultrasonic temperature, power, time, as well as solid–liquid ratio and ethanol volume fraction as experimental factors, the response surface method was employed to optimize the ultrasonic extraction process of polyphenols from C. anisum-olens kernel. Furthermore, the in vitro antioxidant activity of the polyphenols was investigated via free radical scavenging assays, and the antibacterial activity was determined using the well diffusion method. [Results] The optimal extraction process is an ultrasonic power of 94 W, an ultrasonic time …

Study On Structural Characteristics And Immunomodulatory Activity Of Flammulina Velutipes Crude Polysaccharide, Wang Xinnuo, Peng Chujun, Jin Yumeng, Zhang Molan, You Lijun

Food and Machinery

[Objective] To prepare Flammulina velutipes crude polysaccharide (FVP) and evaluate its structural characteristics and immunomodulatory activity. [Methods] FVP was prepared from Flammulina velutipes using hot-water extraction and ethanol precipitation, and its structural characteristics were characterized by combining Fourier transform infrared spectroscopy (FTIR) and high-performance size-exclusion chromatography–multi-angle laser light scattering–refractive index detection (HPSEC–MALLS–RI). The immunomodulatory activity of FVP was evaluated using RAW 264.7 macrophages and a cyclophosphamide-induced immunosuppressed mouse model. [Results] The total sugar content of FVP is (51.39 ± 1.36) g/100 g. Structural characterization results show that FVP has characteristic features of a β-type pyranose ring and exhibits a multi-component …

Comparison And Optimization Of Glycoprotein Extraction Processes For Six Panax Medicinal Herbs Using Ultra-High Pressure Extraction Technology, Chang Fangyu, Zang Hao, Cheng Liye, Han Lusheng, Du Lianyun, Wang Enpeng

Food and Machinery

[Objective] To comprehensively compare and screen glycoprotein preparation processes for six representative medicinal materials from the genus Panax. [Methods] Glycoprotein yield, DPPH radical scavenging capacity, hydroxyl radical scavenging capacity, and Fe2+ chelation inhibition rate were used as evaluation indicators. Glycoprotein extraction rates and antioxidant activities of six medicinal materials, including P. ginseng, P. notoginseng, P. quinquefolius, P. japonicus (T. Nees) C. A. Mey., P. stipuleanatus H. T. Tsai & K. M. Feng, and P. bipinnatifidus Seem, were compared using traditional thermal extraction and ultra-high pressure processing (UHPP). The Box–Behnken response surface method was employed to optimize UHPP parameters for P. …

Optimization Of Probiotic Fermentation Process And Effects Of Drying Methods On The Quality Of Sea Buckthorn Leaves, Dong Xiaoyue, Yun Xueyan, Zhang Lu, Dong Tongliga, Zhao Chenxi, Te Jinwei, Wang Xiukuan, Hao Qian, Miao Meishu, Su Ke

Food and Machinery

[Objective] To investigate the effects of probiotic fermentation conditions and drying methods on the quality of fermented sea buckthorn leaf products. [Methods] Lactiplantibacillus plantarum is used for fermentation. The fermentation process of sea buckthorn leaves is optimized through single-factor experiments combined with response surface methodology. Fermented sea buckthorn leaf extract is prepared under the optimal fermentation conditions and subsequently processed into freeze-dried powder by direct freeze-drying and spray freeze-drying, with or without low-voltage electrostatic field assistance. The effects of different treatments on viable cell counts, flavonoid and polyphenol retention rates, water activity, and in vitro digestion characteristics are evaluated. [Results] …

Extraction Process Optimization Of Camellia Sinensis Flavonoids And Their Antioxidant Activity, Tu Jianqiu, Xu Danhe, Chen Long, Wang Yaxin, Xu Jiahui, Jing Lixiang, Li Jianfang

Food and Machinery

[Objective] To optimize the extraction process of flavonoids from Xinyang Camellia sinensis and to compare the in vitro antioxidant activities of total flavonoids before and after purification. [Methods] Using Xinyang C. sinensis as raw material, a one-factor test is conducted to investigate the effects of ethanol volume fraction, ultrasonic time, ultrasonic power, and material–liquid ratio on the yield of flavonoids. Subsequently, a three-factor, three-level optimization model is established based on the Box–Behnken experimental design. Additionally, a macroporous adsorption resin is utilized for the purification of flavonoid crude extracts. Finally, the in vitro antioxidant activity of the total flavonoids is evaluated …

Research Progress In Production Process And Flavor Modulation Mechanisms Of Cooking Wine, An Nan, Liu Gongliang, Bai Weidong, Tong Xing, Wang Hong

Food and Machinery

As a core condiment in traditional Chinese cuisine, the flavor modulation mechanisms of cooking wine are closely related to its production processes. This review systematically organizes the three major production systems of cooking wine, i.e., brewed, blended, and seasoned, comparing their differences in base-wine origin, flavor-formation pathways, and product stability. By integrating the latest developments in flavoromics, molecular interactions, and intelligent fermentation, it provides a systematic analysis of the relationship between production process differences and flavor formation mechanisms. The paper clarifies the multi-stage “dissolution–modification–suppression” mechanism for off-flavor removal and proposes a metabolic flux-directed process optimization pathway. Additionally, it explores the …