Digital Commons Network^™

Alfred Russel Wallace Notes 42: How Accurate Are The Transcriptions Presented At The Alfred Russel Wallace Page Website?, Charles H. Smith

Faculty/Staff Personal Papers

A look is taken at the level of accuracy displayed by the transcriptions of Wallace writings offered at the Alfred Russel Wallace Page website, as determined by a ChatGPT analysis.

Oak Savanna Expansion: Indigenizing Psu's Urban Landscape, Ash Herb

University Honors Theses

Since time immemorial Indigenous Peoples have resided in what is now named Portland of the Pacific Northwest in the Willamette Valley. For hundreds of years, this forested Land has been colonized, razed to stumps and covered in cement in order to build the urban landscape. Due to such destruction on a broad scale, we are experiencing the results of climate catastrophe. By finding ways to reclaim our relationship with Land and returning to Indigenous epistemologies, our urban landscape has the opportunity to shift towards restoration and prosperity. Indigenous plants have existed here, supporting humans in a reciprocal relationship, for thousands …

A Quantitative Analysis Of Sea Turtle (Chelonia Mydas, Caretta Caretta, And Lepidochelys Kempii) Suture Morphology, Adolfo Emanuel Artigas Iv

Harriet L Wilkes Honors College Theses

Sea turtle shells are formed of modified ribs, which, structurally, are sandwich composites. Sandwich structures provide both physical protection and pressure response associated with diving at depth. Carapacial sutures, tight joints between adjacent bones, connect modified ribs with collagenous fibers. Previous research on freshwater turtle shells suggests that sinuous sutures (highly convoluted) enhance compression strength. Limited research explored the form and functional significance of sutures in marine turtles. To investigate suture morphology and potential ontogenetic effects, I analyzed sutures in green (Chelonia mydas), Kemp’s ridley (Lepidochelys kempii), and loggerhead (Caretta caretta) sea turtles. Samples …

University Of Central Florida Undergraduate Catalog, 2025-2026, University Of Central Florida

UCF Catalogs

No abstract provided.

Computable Phenotypes For Research Using Real-World Data: Experiences From The Nih Pragmatic Trials Collaboratory, Marisa L Conte, Judith M Schlaeger, Guilherme Del Fiol, James R Campbell, Andrea L Cheville, Keith Marsolo, Kari A Stephens, Miriam O Ezenwa, Andrew D Boyd, Juanita E Darby, Nadine S Matthie, P Michael Ho, Alice Pressman, Morgan Justice, Carol Reynolds Geary, Keturah R Faurot, Alex Fist, Karen Staman, Hulin Wu, Rachel L Richesson

Faculty, Staff and Student Publications

Objectives: Embedded pragmatic clinical trials (ePCTs) are conducted as part of routine clinical care and therefore use data collected from real-world data sources, such as electronic health record systems and administrative claims. A common approach for using these types of data across all phases of trial conduct is to create a computable phenotype (an explicitly defined data query data, including specified data types, data codes, and logical parameters) to capture patients with a clinical condition, exposure, symptom, characteristic, treatment, or outcome of interest.

Materials and methods: The Electronic Health Record (EHR) Core Working Group of the NIH Pragmatic Trials Collaboratory …

Indigenous Community Research Opportunities, Sharon Hausam, Aaron M. Canter

Faculty Publications

This is a working paper produced as part of National Science Foundation project #2115169, “Transforming Rural-Urban Systems: Trajectories for Sustainability in the Intermountain West,” known as the “Intermountain West Transformation Network” (TN), led by the University of New Mexico with institutional partners at three additional universities in New Mexico, two in Arizona, and one each in Utah, Colorado, and Washington. The TN’s Indigenous and Tribal engagement was supported through a contract with Dr. Sharon Hausam, additional work by Aaron M. Canter, coordination with Dr. Lani Tsinnajinnie, and an Advisory Committee on Indigenous Information Needs primarily comprised of Indigenous representatives in …

"I Can See Where This Is Taking Me": Medical Students' Perceptions Of Humanities Courses At Aga Khan University, Kenya, Catherine Gathu, Marthaclaire Zammit, Urvi Saboo, Robert Opoka

Family Medicine, East Africa

Background Humanities courses in medical training are increasingly recognized as essential for developing empathetic, reflective and socially responsive physicians. Although well-established globally, their integration into medical education in African contexts remains limited. In Kenya, humanities are often peripheral within curricula dominated by biomedical sciences and clinical medicine. Aga Khan University (AKU), Nairobi, has introduced a novel medical curriculum that embeds seven core humanities courses as central components of the initial phase of its MBChB program. This study explored students’ perceptions and lived experiences of these humanities courses.

Methods A retrospective descriptive study using an embedded mixed-methods design was conducted among …

Spatial And Hydrologic Effects Of Climate Change And Urbanization On Freshwater Fish Communities In North Georgia Watersheds, Mayuko Mizutani

Master's Theses

Urbanization and climate change are altering streamflow and land cover across the southeastern United States, threatening freshwater biodiversity in rivers already burdened by impoundments and habitat loss. I investigated how changes in streamflow and land cover might affect fish community biodiversity in the Etowah River watershed of North Georgia. By combining a dataset of fish collections from 1999 through 2019 with contemporaneous land use and daily streamflow, I was able to model fish community responses to urbanization and climate-driven hydrologic changes and then forecast fish community structure under multiple CMIP6 global climate models and greenhouse gas emissions scenarios (SSP2-4.5 and …

The Influence Of Habitat And Individual Specialization On Mountain Lion (Puma Concolor) Hunting Strategy In A Multi-Prey System, Hannah B. Klugman

All Graduate Theses and Dissertations, Fall 2023 to Present

There is a growing recognition that animal species considered generalists (having a broad and varied diet), are actually specialists, a collection of individuals with different preferences and strategies known as specializations. The diet of a specialist depends on the variety and quantity of available food options, and their own ability to take what they need. Mountain lions (Puma concolor) are known for their ability and tendency to hunt large prey, such as elk (Cervus canadensis) and mule deer (Odocoileus hemionus), but despite the fact they overlap with other potential large prey, like feral horses …

Cadmium Biosorption By Fusarium Venenatum And Its Application In Functional Permeable Materials For Metal Removal, Bradley Lawson

All Graduate Theses and Dissertations, Fall 2023 to Present

Heavy metals are pollutants of increasing concern as continued industrialization and urbanization have escalated the discharge of these toxins into aquatic environments. Cadmium (Cd) is a metal of particular concern due to its acute toxicity and high mobility in aquatic ecosystems. Given these characteristics Cd poses significant health risks to both humans and aquatic ecosystems. The continued development of sustainable, low-cost remediation technology is imperative to manage metal pollution.

This research explores the use of fungal-based remediation systems to remove Cd from contaminated water. Living biomass of the filamentous fungus Fusarium venenatum was evaluated as a biosorbent material for Cd …

Impact Of Trisomy 21 On Post Pull-Through Enterocolitis And Bowel Function In Children With Hirschsprung Disease: A Pcplc Analysis., Marshall W. Wallace, Scott S. Short, Rachel C. Crady, Ron W. Reeder, Hira Ahmad, Kelly Austin, Andrea Badillo, Casey M. Calkins, Megan M. Durham, Julie R. Fuchs, Christopher Gayer, Julia E. Grabowski, Jamie C. Harris, Charles R. Hong, Ankur Rana, Rebecca M. Rentea, Nelson Rosen, Payam Saadai, Caitlin A. Smith, K Elizabeth Speck, Cristine S. Velazco, Richard J. Wood, Michael D. Rollins

Manuscripts, Articles, Book Chapters and Other Papers

INTRODUCTION: We evaluated whether Trisomy 21 (T21) affected bowel management use, ability to toilet train for stool, and rates of Hirschsprung-Associated Enterocolitis (HAEC) in children with Hirschsprung disease (HD). We hypothesized that T21 would be associated with increased rates of HAEC, bowel management program (BMP) use, and delayed toilet training for stool.

METHODS: Children with HD in the Pediatric Colorectal and Pelvic Learning Consortium (PCPLC) database who underwent primary pull-through were included and stratified by T21 status: HD only versus HD + T21. Children requiring a redo pull-through, initially managed with a stoma, or those who had inadequate follow-up were …

Hope Kit Program, Monica Reuber

Capstone Experience: Master of Public Health

Suicide is a leading cause of death in adolescents and young adults, with a disproportionate burden of those deaths in rural areas such as Kansas. High rates of depressive symptoms, suicidal thoughts, and suicidal attempts, combined with a shortage of mental health providers, emphasize the need for community-based intervention.

This capstone is designed to develop a plan for Hope Kits, a proposed suicide prevention program, among youth in grades 7-12 in Sheridan County, Kansas to improve coping skills, promote help-seeking behavior, and reduce suicide risks.

A logic model guides the program development, which aligns with available literature and Social Cognitive …

Georgia Library Association Executive Board Officer Candidates For 2026, Karen Manning

Georgia Library Quarterly

No abstract provided.

An Exploration Of The Psychological Impacts Of Code-Switching, Cristina Culler

Electronic Theses and Dissertations

This dissertation is an interpretative phenomenological analysis of the lived experiences of four Black American adults who have frequently engaged in code-switching. Historically, code-switching has been perceived as a necessary skill that helps marginalized folx adopt the norms and practices of the dominant culture. As a result, code-switching has become a routine practice specifically for Black Americans who often occupy white spaces. Since code-switching has been perceived as a skill, the oppressive origins of code-switching often go unnoticed. Therefore, this dissertation examines code-switching through a critical lens that deems this practice a product of racist ideologies that prioritize whiteness. Through …

Development And Evaluation Of Alternative Mandrel Materials For The Fabrication Of In-House Silicone Vascular Models, Cole Capitani

Master's Theses

Dr. Kristen Cardinal’s Tissue Engineering Laboratory at California Polytechnic State University, San Luis Obispo develops tissue-engineered blood vessel mimics (BVMs) for preclinical testing of neurovascular devices. These BVMs are reliant on silicone vascular models that define the vessel geometry, support endothelial cell attachment, and allow devices to be evaluated in a controlled in vitro environment. Previous work in the lab established injection molding as a viable method for fabricating silicone vascular models and utilized acrylonitrile butadiene styrene (ABS) for sacrificial mandrels. However, this workflow relied on the use of acetone for mandrel dissolution, required single-use mandrels, had extended post-processing times, …

The Information Content Of The Implied Volatility Term Structure Slope For Forecasting Commodity Market Volatility, Lawrence E. Mckenzie

Doctoral Dissertations (DBA)

This study evaluates the implied volatility term structure (IVTS) slope (𝜅) for forecasting 21-day realized volatility against traditional time-series benchmarks and a 3-month continuous futures baseline. Using a matched sample of eight energy and agricultural commodities spanning 2007 to 2019, the study explicitly tests whether the option-implied slope contains unique predictive information beyond deferred price histories. The empirical findings yield three primary insights. First, redundancy testing indicates that the slope parameter delivers a statistically significant, independent risk signal even when controlling for deferred continuous futures paths. Second, an integrated joint encompassing framework that combines near-term historical volatility, generalized autoregressive conditional …

Extending Genome-Wide Association Studies To Admixed Cohorts With High Degrees Of Relatedness, Taotao Tan, Alejandra Vergara-Lope, José Jaime Martínez-Magaña, Nirav N Shah, Yi-Sian Lin, Kai Yuan, Jaime Berumen, Jesus Alegre-Díaz, Pablo Kuri-Morales, Roberto Tapia-Conyer, Joel Gelenter, Janitza L Montalvo-Ortiz, Wei Zhou, Jason M Torres, Elizabeth G Atkinson

Duncan NRI Faculty and Staff Publications

Admixed populations comprise a large portion of the human population worldwide, but are often excluded from genome-wide association studies (GWASs) due to analytic challenges. Our group developed Tractor, a local-ancestry-informed GWAS tool designed for admixed samples that produces accurate ancestry-specific effect sizes and boosts the discovery power to identify ancestry-enriched loci. However, Tractor operates under an assumption of unrelated samples. Here, to address this gap, we propose Tractor-Mix, which allows for well-calibrated association studies in datasets containing admixed samples with relatedness. Extensive simulations show that this method is competitive with other state-of-the-art approaches that do not produce ancestry-specific results. Empirical …

Dupilumab Versus Placebo In Adults And Adolescents With Eosinophilic Gastritis (Degas): A Double-Blind, Placebo-Controlled, Phase 2, Multicentre, Randomised Controlled Trial, Nirmala P Gonsalves, Evan S Dellon, Kara L Kliewer, Tetsuo Shoda, Regina Yearout, Seema S Aceves, Nicoleta C Arva, John A Besse, Julie M Caldwell, Mirna Chehade, Amaziah Coleman, Margaret H Collins, Sara Anvari, Gary W Falk, Sandeep K Gupta, Girish Hiremath, David A Katzka, Paneez Khoury, John Leung, Calies Menard-Katcher, Paul Menard-Katcher, Kathryn A Peterson, Maria A Pletneva, Amanda K Rudman Spergel, Jonathan M Spergel, Tatyana Vaysman, Joshua B Wechsler, Benjamin L Wright, Guang-Yu Yang, Xue Zhang, Meijian Zhou, Ashish Bansal, Bram P Raphael, Amr Radwan, Jennifer Maloney, Antonio Martin, Yamo Deniz, Glenn T Furuta, Lisa J Martin, Marc E Rothenberg

Faculty, Staff and Students Publications

Background: Eosinophilic gastritis currently has no approved treatments and is postulated to be driven by type 2 inflammation. Dupilumab blocks type 2 cytokines IL-4 and IL-13 and has efficacy in multiple diseases characterised by type 2 inflammation, including eosinophilic oesophagitis. We aimed to assess the efficacy and safety of dupilumab in patients with eosinophilic gastritis.

Methods: DEGAS was a proof-of-concept, phase 2, multicentre, randomised controlled trial consisting of a 12-week, double-blind, placebo-controlled period, followed by a 24-week open-label extension period. Patients aged 12-70 years from 11 hospitals in the USA with histologically active eosinophilic gastritis (≥30 eosinophils per high-power field …

Safety And Real-World Effectiveness Of Eptacog Beta With Emicizumab Prophylaxis: An Interim Analysis Of The Athn 16 Study., Tammuella Chrisentery-Singleton, Suchitra Acharya, Sanjay Ahuja, Lauren Amos Md, Meera Chitlur, Nabil Daoud, Ashley Eason, Miguel Escobar, Carol Fedor, Shveta Gupta, Philip Kuriakose, Sonia Nasr, Sharon Pennington, Rajiv K. Pruthi, Michael Recht, Andreana Robertson, Doris V. Quon, Allison P. Wheeler, Mark Reding

Manuscripts, Articles, Book Chapters and Other Papers

Eptacog beta, a recombinant factor VIIa bypassing agent, has demonstrated safety and efficacy in the management of bleeding events (BEs) in people with hemophilia and inhibitors. Data describing eptacog beta use in patients receiving emicizumab prophylaxis remains limited. This interim analysis of the American Thrombosis and Hemostasis Network 16 study, a phase 4, multicenter, US based, open-label study, evaluates the safety and real-world effectiveness of eptacog beta for the treatment of BEs experienced on emicizumab prophylaxis. Nineteen participants with hemophilia A and inhibitors who agreed to treat BEs with eptacog beta were included. Eptacog beta dosing was determined by the …

Cyp2c19 C.681g>A Is Not In Complete Linkage Disequilibrium With C.332-23a>G: Implications For Pharmacogenetic Testing., Amy J Turner, Erin C. Boone, Cyrine E Haidar, Wenjian Yang, Ashley D Derezinski, Andrew Haddad, Philip E. Empey, Ulrich Broeckel, Andrea Gaedigk

Manuscripts, Articles, Book Chapters and Other Papers

CYP2C19 plays an important role in the metabolism of many medications, including the antiplatelet agent clopidogrel, the antifungal agent voriconazole, selective serotonin reuptake inhibitors, select tricyclic antidepressants, and proton pump inhibitors. The Clinical Pharmacogenetics Implementation Consortium has published several guidelines emphasizing the importance of CYP2C19 genotype-guided therapy to optimize patient outcomes. Formerly, the no function CYP2C19*2 allele was defined by three variants, c.332-23A>G (splice defect), c.681G>A (splice defect), and c.991A>G (p.I331V). The discovery of two new haplotypes, one containing only a single variant, c.681G>A, and another with only c.681G>A and c.991A>G, challenged the assumption …

Are We Winning At Twinning? Persistent Cni Use In Identical Kidney Transplants., Nicholas S. Herrera, Shivani Wadnerkar, Diane M. Cibrik

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Calcineurin inhibitors (CNIs) revolutionized kidney transplantation by reducing acute rejection rates. Identical twin kidney transplantation is the only setting in which the allograft is immunologically indistinguishable from self, yet CNI use persists. We characterized CNI utilization across end-stage kidney disease etiologies and examined whether CNI exposure was associated with reduced rejection or improved death-censored graft survival (DCGS).

METHODS: We performed a retrospective cohort study using scientific registry of transplant recipients data (January 2000-August 2025). Among 255 adult identical twin kidney transplant recipients, discharge regimens were categorized by CNI use; Firth penalized Cox regression was the primary method for 10-year …

Secondary Biology Teachers’ Understandings Of Growth Mindset, Kathryn Chapman

Dissertations

This case study investigates how high school biology teachers understand and apply growth mindset principles in their daily instruction. Using surveys, semi‑structured interviews, and focus groups, the study examines how biology teachers interpret mindset, how they attempt to enact it, and how curriculum demands shape their efforts. Findings show that teachers’ beliefs about intelligence strongly influence their feedback, expectations, and instructional decisions. Teachers described biology as a subject in which struggle is highly visible, emotionally charged, and often tied to students’ prior knowledge, making mindset work both necessary and challenging. Results also indicate that students’ mindsets are shaped by broader …

Purdue University General Institutional Description, Purdue University Office Of Research

University General Facility Boilerplate Descriptions

Overview of Purdue University mission, statistics, and key cross-campus infrastructure.

Exploring The Paradoxical Association Between Chest Ct Pulmonary Involvement And Olfactory Dysfunction In Covid-19 Patients: A Prospective Cross-Sectional Study, Abdolkarim Ghadimi-Moghadam, Saed Askari, Mohammad Amin Ghatee, Alireza Mortazavi, Saeed Javdansirat, Ali Ghadimi Moghadam, Hassan Vafapour, Zaker Salehi, Seyed Mohammad Javad Mortazavi, Lembit Sihver

Informatics and Engineering Systems Faculty Publications

Background and Aims: Olfactory dysfunction (OD) is common in COVID-19, yet its relationship with pulmonary involvement remains inconsistent. We evaluated the association between CT-based lung involvement and OD in laboratory-confirmed COVID-19.

Methods: In a prospective cross-sectional study (Yasuj University of Medical Sciences hospitals; December 26, 2021–May 22, 2022), OD was assessed using the CCCRC protocol and pulmonary involvement was categorized using a CT lung involvement score. Associations were examined using chi-square testing (categorical) and ANOVA where appropriate (α = 0.05).

Results: Among 120 patients (60 male/60 female; mean age 43.17 ± 14.76 years), 71 (59.2%) had hyposmia, and none had …

Friends Of The Library Newsletter, Summer/Fall 2026, Hillary Richardson

Fant Library News and Reports

No abstract provided.

Review: Mechanics Of Mycelium Materials, Md Anwar Sadat Anik, Ehsanul Azim, Gerardo I. Zapata, Mohammad R. Islam

Mechanical Engineering Faculty Publications

The biological growth of fungal root structure, called mycelium, can be engineered to develop innovative fibrous and biocomposite materials. Mycelium materials have potential as sustainable alternatives to petroleum-derived materials for load-bearing applications. To realize this potential, there is an increasing effort dedicated to understanding the mechanics of mycelium materials. This work presents a systematic review of our current understanding of the mechanics of mycelium materials with a specific focus on structure–property relationships. The review first explores how the mycelium’s fiber network structure varies depending on whether it is grown as a two-dimensional (2D) membrane, a cellular foam, or as a …

The Rpm-1/Phr Signaling Hub Modulates Tau-Induced Neurodegeneration Through Regulation Of Microtubule Stability And Mapk Pathways In C. Elegans, Xinxing Ding

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's disease and frontotemporal dementia, are characterized by the accumulation of pathological tau proteins and progressive neuronal loss. Although research regarding tau-mediated toxicity is extensive, the specific pathology that determine whether neurons maintain homeostasis or succumb to collapse under tau-induced stress remain incompletely elucidated. A central, yet still insufficiently understood, feature of these diseases is the disruption of the microtubule (MT) cytoskeleton . The PHR protein family is evolutionarily highly conserved; within this family, RPM-1 in C. elegans functions as an intracellular signaling hub that regulates axon development, synapse formation, axon termination, and various microtubule-associated processes. This …

The Influence Of Ecological Pest Management Practices On Pests And Natural Enemies Under A Cabbage–Garden Pea Rotational System In Central Kenya, Peter Nyakundi Mageto, Milka Kiboi, Monicah Mucheru-Muna, Felix Matheri

All Peer-Reviewed Publications

Pest pressure is a major constraint on crop production in Sub-Saharan Africa, where smallholder farmers rely heavily on synthetic pesticides with potential environmental and health risks. Ecological pest management practices (EPMs) have been proposed as sustainable alternatives, although field-based evidence is limited. This study evaluated pest and natural-enemy responses to EPMs in a cabbage–garden pea rotation system over six years (2020–2025) in Central Kenya. Four treatments were assessed: homemade botanical extracts (Botanicals), coriander intercropping (Intercrop), botanical extracts combined with coriander intercropping (Botanicals + Intercrop), and a control. In cabbage, ecological treatments often recorded lower aphid and diamondback moth abundance and …

Listening To Fire: Using Passive Acoustic Monitoring To Detect And Explain Prescribed Fire Effects On Avian Communities In Oak-Hickory Forests Of The Central Hardwood Region, Wesley Petty

Dissertations

Prescribed fire is an increasingly important tool for restoring oak-hickory forests in the Central Hardwood Region, yet its effects on avian communities remain poorly understood because traditional monitoring methods cannot easily capture wildlife responses across the large spatial and fine temporal scales at which fire effects unfold. This dissertation develops and tests a framework for using passive acoustic monitoring (PAM) to detect prescribed fire effects on avian communities and to explain the ecological mechanisms behind them. Acoustic data were collected at Giant City State Park and Touch of Nature Environmental Center in southern Illinois across six recording sites for seven …

Dissecting Ms4a4a Function In Microglia And Its Role In Alzheimer’S Disease Pathogenesis, Emma Pascal Danhash

Arts & Sciences Graduate Student Theses and Dissertations

Genome-wide association studies have begun to uncover the complex genetic architecture of Alzheimer's disease (AD). Expression of many AD risk loci is enriched in microglia, the resident immune cells of the brain. Common variants near the MS4A gene family have been associated with AD risk and altered soluble triggering receptor expressed on myeloid cells 2 (sTREM2) levels in the cerebrospinal fluid (CSF). MS4A4A is a microglial gene that encodes a tetraspan membrane protein that regulates anti-inflammatory responses in macrophages. However, the mechanism by which MS4A4A contributes to microglial function and AD pathogenesis remains unknown. In this dissertation, I leveraged a …