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Articles 1831 - 1860 of 18232
Full-Text Articles in Entire DC Network
August 2026 News Releases, University Of Montana--Missoula. Office Of University Relations
August 2026 News Releases, University Of Montana--Missoula. Office Of University Relations
University of Montana News Releases, 1928, 1956-present
No abstract provided.
Fisheries Research Report No. 365: Recreational Fishing For Marron In South-West Western Australia In 2026, Claire B. Smallwood, Karina L. Ryan, Eva Lai
Fisheries Research Report No. 365: Recreational Fishing For Marron In South-West Western Australia In 2026, Claire B. Smallwood, Karina L. Ryan, Eva Lai
Fisheries Research Reports
The smooth marron (Cherax cainii) (‘marron’) is endemic to freshwater dams and rivers of south-west Western Australia. Marron are managed as a single stock within the South-West Recreational Freshwater Resource and are highly vulnerable to overexploitation due to the biological characteristics of the species (e.g., low fecundity, localised populations) as well as environmental (e.g., habitat loss, reduction in rainfall) and human (e.g., fishing, land clearing) pressures on freshwater ecosystems.
Due to this vulnerability, this species has been the focus of research, monitoring and management since the 1970’s. Since 2000, annual phone-recall (2000 – 2021) and online-recall (2022 – 2026) surveys …
Reading The Western Canon From Elsewhere: Teaching Political Theory Through Writing, Zlata Božac
Reading The Western Canon From Elsewhere: Teaching Political Theory Through Writing, Zlata Božac
GHEA21 Publications
No abstract provided.
Transgender And Gender-Diverse Healthcare Through Virtual Social Networking, Francis Peter Furmanek Iii
Transgender And Gender-Diverse Healthcare Through Virtual Social Networking, Francis Peter Furmanek Iii
PhD of Social Work
This study examined the behavior of transgender and gender diverse (TGD) utilizing virtual social networking (VSN) to address their healthcare needs. Presently, the TGD community has been facing discrimination in policy and social structure across the United States. Accepting safe spaces are vital to survival and growth of TGD people, and the current wave of anti-trans legislation seeks to eliminate these spaces. This phenomenological mixed-methods study examined mechanisms that TGD people use to address healthcare needs in virtual spaces alongside a backdrop of negative healthcare experiences in traditional settings. Informed by Intersectional theory, Minority Stress Theory, and considering Andersen’s Behavioral …
Improving Obesity Management In Primary Care Through Provider Education, Natalie Anderson
Improving Obesity Management In Primary Care Through Provider Education, Natalie Anderson
Doctor of Nursing Practice Projects
Background: Childhood obesity is a significant public health concern associated with metabolic, cardiovascular, and psychosocial complications. Despite the availability of evidence-based pediatric obesity management guidelines, adherence to these guidelines remains inconsistent in primary care settings. Purpose: This evidence-based quality improvement project aimed to determine whether provider education on the 2023 American Academy of Pediatrics (AAP) Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity, combined with implementation of an electronic health record (EHR) clinical decision support prompt, improved provider knowledge and adherence to guideline-recommended obesity management practices. Method: A pre-post quasi-experimental study was …
Aegic Blogposts - Grain Industry Productivity, Ross Kingwell
Aegic Blogposts - Grain Industry Productivity, Ross Kingwell
Grain and other field crops published reports
The Australian Export Grains Innovation Centre (AEGIC) was an independent, not-for-profit organisation established in 2012 by the Western Australian Government and the Grains Research and Development Corporation (GRDC). Its core mission was to increase the value and international competitiveness of Australia’s multibillion-dollar export grains industry. AEGIC ceased operation at the end of 2025.
Early in its history between 20 to 30 staff from the former Western Australian Department of Agriculture were seconded to AEGIC. Following the formation of DPIRD, AEGIC continued to receive substantial annual funding support from DPIRD.
This publication is a legacy document containing collated AEGIC blog posts …
Professor Greenfeld’S Last Class: Notes For Online Lectures On “The Science Of Humanity,” Delivered To Students And Scholars Primarily From India, July 2025, Liah Greenfeld
Comparative Civilizations Review
The question for this class is: What is humanity?
We all believe we all know what it is, don’t we? After all, there is hardly any subject more important for us, a question on the answer to which other subjects depend — political, social, economic. Answers to questions such as: what are human economic needs and desires; what political structures are optimal for humans; is democracy, for instance, a universal human desire; should politics in every nation be democratic, or, perhaps, authoritarian governments are better; is freedom a natural need, does it make life better, does equality?
A Study Of Phylogenetic Relationships Of Dichanthelium Based On Plastomes, Humera Fatima
A Study Of Phylogenetic Relationships Of Dichanthelium Based On Plastomes, Humera Fatima
Theses
Dichanthelium (Hitchcock & Chase) Gould is a genus in the grass family (Poaceae) with a wide range of morphological diversity, exhibiting significant ecological differences. Despite this, its evolutionary relationships are not fully understood. The ambiguity surrounding the boundaries of lineages and the relationships among species has hindered the systematics of the genus. This study aimed to reconstruct the phylogenetic relationships within Dichanthelium, verify the monophyly of species, and evaluate the strength of the inferred relationships across different analytical frameworks. Molecular sequence data of entire plastomes were examined using both maximum likelihood and Bayesian inference methods to develop phylogenetic hypotheses. Phylogenies …
B.R. Wells Arkansas Rice Research Studies 2025, J. Hardke, X. Sha, N. Bateman
B.R. Wells Arkansas Rice Research Studies 2025, J. Hardke, X. Sha, N. Bateman
Arkansas Agricultural Experiment Station Research Series
Arkansas is the leading rice producer in the United States. The state represents 45.2% of total U.S. rice production and 45.7% of the total acres planted to rice in 2025. Rice cultural practices vary across the state and across the U.S. However, these practices are also dynamic and continue to evolve in response to changing political, environmental, and economic times. This survey was initiated in 2002 to monitor and record changes in the way Arkansas rice producers approach their livelihood. The survey was conducted by polling county extension agents in each of the counties in Arkansas that produce rice. Questions …
A Finite Element Model To Analyze Crack-Tip Fields In A Transversely Isotropic Strain-Limiting Elastic Solid, Saugata Ghosh, Dambaru Bhatta, S. M. Mallikarjunaiah
A Finite Element Model To Analyze Crack-Tip Fields In A Transversely Isotropic Strain-Limiting Elastic Solid, Saugata Ghosh, Dambaru Bhatta, S. M. Mallikarjunaiah
School of Mathematical & Statistical Sciences Faculty Publications
This paper presents a finite element model for the analysis of crack-tip fields in a transversely isotropic strain-limiting elastic body. A nonlinear constitutive relationship between stress and linearized strain characterizes the material response. This algebraically nonlinear relationship is critical as it mitigates the physically inconsistent strain singularities that arise at crack tips. These strain-limiting relationships ensure that strains remain bounded near the crack tip, representing a significant advancement in the formulation of boundary value problems (BVPs) within the context of first-order approximate constitutive models. For a transversely isotropic elastic material containing a crack, the equilibrium equation, derived from the balance …
Quaking Aspen On Cedar Mountain, Utah: Status And Update, Jaycee Cappaert, Larissa L. Yocom, Paul C. Rogers, Darren J. Mcavoy, R. Justin Derose
Quaking Aspen On Cedar Mountain, Utah: Status And Update, Jaycee Cappaert, Larissa L. Yocom, Paul C. Rogers, Darren J. Mcavoy, R. Justin Derose
Wildland Resources Student Research
Quaking aspen forests are important communities in the western United States where they provide preferential food and habitat for animals, limit wildfires from spreading, and have favorable aesthetics, among other things. Their putative decline is an issue for ecology and management. We remeasured the aspen population on Cedar Mountain, Utah, to assess changes to its condition since it was originally measured in 2008 and laid the groundwork for continued aspen monitoring on Cedar Mountain. Our objectives were to compare current metrics of stand structure and composition, mortality, crown dieback, bole damage, regeneration, and recruitment, to those of the original inventory. …
Summaries Of Arkansas Cotton Research 2025, Fred M. Bourland
Summaries Of Arkansas Cotton Research 2025, Fred M. Bourland
Arkansas Agricultural Experiment Station Research Series
Planted cotton acreage in Arkansas decreased in 2025 to 520,000 acres compared to 650,000 planted acres in 2024. Arkansas producers harvested 515,000 acres, which was a decrease of 125,000 acres from the 640,000 acres harvested in 2024 (https://www.nass.usda.gov/Quick_Stats/Ag_Overview/stateOverview.php?state=Arkansas&year=2025). The 515,000 harvested acres ranked Arkansas third nationally, trailing only Texas and Georgia in harvested acres (https://esmis.nal.usda.gov/sites/default/release-files/795725/cropan26.pdf). The average cotton yield, as reported by the USDA, was 1,239 lb lint/ac, which ranked fourth nationally, behind California, Louisiana, and Arizona. Arkansas farmers produced an estimated 1.329 million bales, which is a decrease from 1.788 million bales produced in 2024. This production still ranks …
Agent-Based Modeling Of Cellular Dynamics In Adoptive Cell Therapies, Yujia Wang
Agent-Based Modeling Of Cellular Dynamics In Adoptive Cell Therapies, Yujia Wang
Dissertations and Theses (Open Access)
Adoptive cell therapies (ACT) have shown promising progress in combating cancer, but clinical responses remain heterogeneous. Key determinants, including the functional states of infused cells, tumor–immune interactions, and dosing strategies, are difficult to resolve experimentally in the dynamic and heterogeneous tumor microenvironment, limiting optimization of ACT products and treatment regimens. To address the gap, we developed ABMACT (Agent-Based Model for Adoptive Cell Therapies), a computational framework that reconstruct key cellular functions, interactions, and molecular signatures to recapitulate cell population dynamics associated with differential treatment responses. ABMACT encodes autonomous “virtual cells” using literature-informed rules calibrated with experimental data, enabling simulation of …
Transcriptional Regulation In The Uterine Luminal Epithelium, Evelyn A. Carrion
Transcriptional Regulation In The Uterine Luminal Epithelium, Evelyn A. Carrion
Dissertations and Theses (Open Access)
Transcriptional Regulation in the Uterine Luminal Epithelium
Evelyn A. Carrion
Advisor: Richard R. Behringer, PhD
Abstract
The uterus is an organ comprised of multiple tissues that are essential for women’s health and reproduction. The uterus is composed of multiple tissue layers, including the perimetrium, myometrium, and the endometrium. The endometrium is the inner lining of the uterus, and contains the luminal epithelium, glandular epithelium, and stroma. The luminal epithelium is a simple columnar layer of cells that is necessary for embryo implantation. The uterus is derived in part from the embryonic precursor tissue called the Müllerian duct. There are no …
Ai-Driven Segmentation And Volumetric Response Modeling Of Liver Regions To Radiotherapy, Aashish Chandra Gupta
Ai-Driven Segmentation And Volumetric Response Modeling Of Liver Regions To Radiotherapy, Aashish Chandra Gupta
Dissertations and Theses (Open Access)
In liver-directed radiotherapy (RT), liver regions receiving higher doses typically undergo atrophy while contralateral/adjacent lower-dose regions may exhibit compensatory hypertrophy through regeneration of healthy tissue. Optimizing the RT plan to promote regional hypertrophy while minimizing the risk of developing atrophy has the potential to enhance post-RT liver function and long-term survivorship. However, current clinical practice largely relies on global liver dose-volume metrics during RT-planning, which may obscure favorable dose-response correlation and limit actionable guidance for clinicians. Therefore, we hypothesized that post-RT regional liver response is governed by a combination of region-specific dose-volume and patient clinical features, and that these responses …
Regulation Of Müllerian Duct Mesenchyme Transcription During Mammalian Sex Differentiation, Haowen Li, Richard R Behringer, Rachel D Mullen
Regulation Of Müllerian Duct Mesenchyme Transcription During Mammalian Sex Differentiation, Haowen Li, Richard R Behringer, Rachel D Mullen
Dissertations and Theses (Open Access)
Sp7/Osterix (Osx) encodes a zinc-finger transcription factor of the Specificity-protein family discovered by Nakashima et al. at the MD Anderson Cancer Center. While primarily recognized for its role in osteogenesis, Osx has also been implicated in mammalian reproductive development, particularly in male sex differentiation, where Müllerian Duct (MD) regression occurs, mediated by anti-Müllerian hormone (AMH) signaling. AMH-induced regression signals are transduced by the mesenchymal tissue surrounding the ductal structure, known as the Müllerian Duct mesenchyme (MDM). It was discovered that AMH signaling is necessary and sufficient for driving Osx expression in MDM. A previous transgenic mouse reporter …
Oxidative Stress Mediated Glutamate Release And Nmda Receptor-Dependent Synaptic Remodeling In Radiation-Induced Cognitive Dysfunction, Thanh Lam
Dissertations and Theses (Open Access)
In children younger than 14 years old, the brain and other parts of the central nervous system are the most common sites for solid tumors. Radiotherapy is an effective treatment for central nervous system (CNS) tumors. However, it often causes a progressive decline in cognitive functions, which is especially devastating for pediatric patients. Although post-mitotic neurons are generally considered resistant to radiation-induced immediate cell death, ionizing radiation causes complex neurochemical and structural changes that damage synaptic integrity. In this study, we examined the molecular cascades following a 10 Gy radiation dose applied to mouse cortical neurons. We found that radiation-induced …
From Geometry To Recognition: A Quantitative Framework For Tcr-Pmhc Structural Analysis In The Age Of Predicted Structures, Kun Hee Kim
Dissertations and Theses (Open Access)
Recognition of antigen by a T cell begins with a single physical event, the engagement of the T cell receptor (TCR) with a peptide-major histocompatibility complex (pMHC), and this interaction is encoded in the geometry with which the receptor docks onto the composite pMHC surface. Whether that docking geometry is biologically organized, and whether the structures now produced at scale by prediction preserve recognition or only reproduce that organization, are the two questions this thesis addresses. Two gaps stand in the way. The first is a gap of measurement, because docking geometry has never been made quantitatively comparable across many …
Antigen Discovery In Multiple Myeloma Using Integrated Long-Read Transcriptomics And Immunopeptidomics, Aya Albittar
Antigen Discovery In Multiple Myeloma Using Integrated Long-Read Transcriptomics And Immunopeptidomics, Aya Albittar
Dissertations and Theses (Open Access)
Multiple myeloma (MM) remains an incurable plasma cell malignancy, with relapse driven by persistent chemotherapy-resistant cells and residual disease following treatment. Although immunotherapies have transformed MM care, their success depends on identifying tumor-specific antigens that can be safely targeted. While aberrant genomic structural variation and transcriptional dysregulation are increasingly recognized as sources of novel antigens in MM, the HLA-presented antigenic landscape of MM remains incompletely characterized, particularly for non-canonical, structurally-derived peptides, and long-read transcriptome-informed immunopeptidomic data specific to MM remain scarce.
We established an integrated antigen discovery platform combining long-read RNA sequencing (Iso-Seq) with mass spectrometry-based HLA immunoprecipitation and immunopeptidomics …
Low-Cost Modular Transradial Prosthetic System, Caleb E. Barajas
Low-Cost Modular Transradial Prosthetic System, Caleb E. Barajas
Master's Theses
Upper-limb loss can significantly impact overall quality of life by limiting a person's ability to perform activities of daily living (ADLs). Although prosthetic devices can help bridge the gap, many upper-limb prostheses are limited by high costs, discomfort, limited repairability, and accessibility barriers. Current commercial myoelectric prosthetic hands can provide high levels of functionality, but are often expensive and require specialized clinical access. In contrast, many current low-cost and open source prosthetic devices improve affordability but are limited in function or designed for partial hand applications rather than full transradial limb loss.
The purpose of this thesis was to design, …
A Critical-Constructivist Grounded Theory Exploration Of The Mental Health Experiences Of Individuals With Intellectual Disabilities In Post-Secondary Settings, Alyssa L. Decker
A Critical-Constructivist Grounded Theory Exploration Of The Mental Health Experiences Of Individuals With Intellectual Disabilities In Post-Secondary Settings, Alyssa L. Decker
Dissertations, 2020-current
Individuals with intellectual disabilities (ID) now have access to higher education, often through inclusive post-secondary education programs (IPSE), to increase employability and quality of life. IPSE programs, historically, have provided academic and life skill support and not mental health support within programs’ curricula. A recent review of IPSE programs reveals that if mental health services are included, they are often accessed through university health services. Transitioning from high school to college induces high levels of stress, which can exacerbate underlying mental health conditions. Mental health care is defaulted to an already overburdened college counseling center without the knowledge and skills …
Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Major Depressive Disorder, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Katja Beesdo-Baum, Mark A. Bellgrove, Vivek Benegal, Anderson M. Winkler
Shared And Distinct Alterations In Brain Structure Of Youth With Internalizing Or Externalizing Disorders: Findings From The Enigma Antisocial Behavior, Adhd, Major Depressive Disorder, And Anxiety Working Groups, Sophie Townend, Marlene Staginnus, Yidian Gao, Nina Alexander, Volker Arolt, Tobias Banaschewski, Katja Beesdo-Baum, Mark A. Bellgrove, Vivek Benegal, Anderson M. Winkler
Human Genetics Publications
Background: Externalizing and internalizing disorders are common in youth but are often studied separately, preventing researchers from identifying shared (i.e., transdiagnostic) alterations in brain structure. Using data from the ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Consortium, we conducted a mega-analysis to identify shared and distinct cortical and subcortical brain alterations across internalizing (anxiety disorders and depression) and externalizing (attention-deficit/hyperactivity disorder [ADHD] and conduct disorder [CD]) disorders in youth.
Methods: 3D T1-weighted magnetic resonance imaging data from youths (age range 4-21 years) with anxiety disorders (n = 1044), depression (n = 504), ADHD (n = 1317), and CD (n = 1172) …
Visual Cues Attract Adult Tunga Penetrans (Siphonaptera: Tungidae), Ayako Hyuga, Paul Ouma, Lynne Elson, Kazuchiyo Miyamichi, Satoshi Kaneko, Kensuke Goto, Tullu Bukhari, Jürgen Krücken, Ulrike Fillinger
Visual Cues Attract Adult Tunga Penetrans (Siphonaptera: Tungidae), Ayako Hyuga, Paul Ouma, Lynne Elson, Kazuchiyo Miyamichi, Satoshi Kaneko, Kensuke Goto, Tullu Bukhari, Jürgen Krücken, Ulrike Fillinger
All Peer-Reviewed Publications
Tunga penetrans (Linnaeus, 1758) (Siphonaptera: Tungidae) is an ectoparasitic flea whose adult females cause tungiasis by embedding into the host’s skin. Environmental, social and financial challenges in tungiasis endemic areas have left this disease neglected and lacking locally available control measures. One possible approach for controlling T. penetrans targets its off-host stages; however, surveillance tools for adult fleas are still lacking. Moreover, host-seeking cues and behaviour of adult T. penetrans remain largely unknown. In this study, we show that visual cues are attractive to adult T. penetrans. Newly emerged T.penetrans responded to light stimuli across a broad spectrum, ranging from …
Engagement Of Understudied Populations As Community Change: The South Texas Adrc Model, Gladys E. Maestre, Neela K. Patel, Rosa V. Pirela, Robin C. Hilsabeck, Kendra Stine, Neyra García, Roberto Reyes, Omar Oropeza, Cristian Maestre, Jesus D. Melgarejo, Sarah Williams-Blangero, Ney Alliey Rodriguez
Engagement Of Understudied Populations As Community Change: The South Texas Adrc Model, Gladys E. Maestre, Neela K. Patel, Rosa V. Pirela, Robin C. Hilsabeck, Kendra Stine, Neyra García, Roberto Reyes, Omar Oropeza, Cristian Maestre, Jesus D. Melgarejo, Sarah Williams-Blangero, Ney Alliey Rodriguez
School of Medicine Publications
Many populations experiencing the highest burdens of Alzheimer's disease and related dementias remain understudied, in part because traditional recruitment and retention models are insufficient to support sustained engagement. The Outreach, Recruitment, and Engagement Core (OREC) of the South Texas Alzheimer's Disease Research Center reconceptualized participant recruitment as a long-term system change in a Hispanic-majority, urban–rural region. OREC institutionalizes shared power through community advisory governance, aligns research protocols with local lived realities (through patient navigators, community health workers/promotores, and decentralized access points), and employs a data-driven feedback loop for continuous improvement. In 1 year, 46 outreach events touched 10,134 individuals (71% …
Race-Associated Egfr And Kras Mutation Profiles In Lung Adenocarcinoma, Lovyanne Vergel De Dios, Catherine Wu, Salique Hassan Shaham, Manish K. Tripathi
Race-Associated Egfr And Kras Mutation Profiles In Lung Adenocarcinoma, Lovyanne Vergel De Dios, Catherine Wu, Salique Hassan Shaham, Manish K. Tripathi
School of Medicine Publications
Background: Lung adenocarcinoma (LUAD) is the most prevalent histologic subtype of non-small cell lung cancer (NSCLC) and exhibits considerable molecular heterogeneity. Among the most clinically significant driver alterations are mutations in EGFR and KRAS, both of which influence treatment selection and oncologic outcomes. The prevalence of these mutations varies by race, yet racial minority populations remain underrepresented in genomic studies. EGFR alterations are more frequently observed in Asian patients, while KRAS mutations predominate in non-Asian cohorts. This study aimed to characterize race-associated differences in driver mutation prevalence among Asian, Black, and White patients with LUAD. Methods: A retrospective secondary cohort …
Global Prevalence Of Depression Among University Students: A Comprehensive Umbrella Review, Gilda Yun Kai Sam, Xun Ci Soh, Harshitha Balaji, Gabriel X. D. Tan, Shu Fen Diong, Meilan Hu, Andree Hartanto, Nadyanna M. Majeed
Global Prevalence Of Depression Among University Students: A Comprehensive Umbrella Review, Gilda Yun Kai Sam, Xun Ci Soh, Harshitha Balaji, Gabriel X. D. Tan, Shu Fen Diong, Meilan Hu, Andree Hartanto, Nadyanna M. Majeed
Research Collection School of Social Sciences
Depression has become a major concern for educational institutes due to its increasing incidence and detrimental impacts on students’ well-being. However, its global prevalence in the context of tertiary education remains unclear. This umbrella review summarised existing meta-analyses and systematic reviews to examine the worldwide prevalence of depression among university students. Several sociodemographic and methodological factors, including differences in depression prevalence before, during, and after COVID-19, were examined as moderators. Structured and exhaustive searches were conducted in five bibliographic databases and five journals, alongside two sources of grey literature. A total of 61 meta-analyses and systematic reviews were included in …
The Ambivalent Wisdom Of Moral Disgust, Brandon Yip
The Ambivalent Wisdom Of Moral Disgust, Brandon Yip
Research Collection School of Social Sciences
This paper has two aims. First, to provide a positive account of moral disgust. I suggest that moral disgust is a response to acts that are socially corrosive, namely, acts that undermine the normative structure to which an agent is attuned. I support this analysis with two lines of evidence: (1) moral disgust serves the important function of guarding normative structures from socially corrosive actions and (2) the analysis provides an illuminating explanation of moral disgust in a wide variety of cases. The secondary aim of this paper is to probe the normative implications of my positive account. I suggest …
Systemic Corticosteroids In The Management Of Sinonasal Disease: An Evidence-Based Expert Review, Andrew Thamboo, Deanna Gigliotti, Eugenio De Corso, Stella Lee, Benjamin S Bleier, Christopher J Chin, Marie-Noelle Corriveau, Valerie Hox, Claire Hopkins, Peter H Hwang, Arif Janjua, Ludger Klimek, Daniel Lee, John Lee, Amber Luong, Geoffrey Mortuaire, Joaquim Mullol, Zara M Patel, John Scott, Doron Sommer, Leigh Sowerby, Marc Tewfik, Beatrice Voizard, Martin Wagenmannm, Sarah K Wise, Jonathan Yip, Quirina Thompson, Martin Desrosiers, Yvonne Chan
Systemic Corticosteroids In The Management Of Sinonasal Disease: An Evidence-Based Expert Review, Andrew Thamboo, Deanna Gigliotti, Eugenio De Corso, Stella Lee, Benjamin S Bleier, Christopher J Chin, Marie-Noelle Corriveau, Valerie Hox, Claire Hopkins, Peter H Hwang, Arif Janjua, Ludger Klimek, Daniel Lee, John Lee, Amber Luong, Geoffrey Mortuaire, Joaquim Mullol, Zara M Patel, John Scott, Doron Sommer, Leigh Sowerby, Marc Tewfik, Beatrice Voizard, Martin Wagenmannm, Sarah K Wise, Jonathan Yip, Quirina Thompson, Martin Desrosiers, Yvonne Chan
The Brown Foundation: Institute of Molecular Medicine
Background: Chronic rhinosinusitis (CRS) is a prevalent, heterogeneous inflammatory disease associated with significant morbidity. Systemic corticosteroids (SCS) are commonly prescribed for their anti-inflammatory effects, but cumulative exposure carries risks, including metabolic, cardiovascular, and skeletal complications. Despite widespread use, evidence-based guidance on optimal indications, timing, and duration of SCS in CRS remains inconsistent.
Methodology/principal: An evidence-based review was performed using MEDLINE, EMBASE, and Cochrane databases (2013-2023). Studies were screened and categorized into two primary groups: CRS with (CRSwNP) or without (CRSsNP) nasal polyps. Within CRSwNP, evidence was subcategorized by indication, including (1) polyp size reduction, (2) olfactory dysfunction, (3) comorbid disease, …
Understanding Hypertensive Renal Injury: A Well-Structured Approach, Peter A Doris
Understanding Hypertensive Renal Injury: A Well-Structured Approach, Peter A Doris
The Brown Foundation: Institute of Molecular Medicine
No abstract provided.