Digital Commons Network^™

Leveraging Machine Learning Techniques To Identify Catastrophic Outliers In Photometric Redshift Estimates, Jason Yoo

Honors Theses

Leveraging the unprecedented data volumes from modern astronomical surveys, this work addresses the critical challenge of identifying catastrophic outliers (COs) in photometric redshift (photo-z) estimates. Reliable redshift estimation is essential for precision cosmology, yet COs (galaxies with severely erroneous photo-z) can introduce significant systematic bias. We develop and evaluate two machine learning approaches for robust CO identification: a multilayer perceptron (MLP) utilizing photo-z point estimates and probability distributions, and a convolutional neural network (CNN) leveraging raw 5-band photometric images. Using datasets emulating LSST conditions, we demonstrate that the MLP model achieves high accuracy and stability across redshift bins, correctly identifying …

Ashley Hanson '82-Ellen Hofheim Bettmann '66, Ashley Hanson, Ellen Bettmann

Alumni Oral History Project

No abstract provided.

High School Daze, Sylvia Perez, And La Llorona, Manuel F. Medrano

History Faculty Publications

No abstract provided.

Where Mussels Hang Out: A Multiscale Analysis Of Zebra Mussel (Dreissena Polymorpha) Spread In South Dakota, Justin Verner Sorensen

Dissertations and Theses

The spread of the invasive zebra mussel (Dreissena polymrpha) poses significant ecological and economic threats to freshwater systems across North America. Understanding population dynamics and how this aquatic invasive species spreads is essential for making natural resource management decisions. South Dakota represents an active frontline of the zebra mussel invasion, highlighting the importance of understanding the spread in this region. Statewide habitat suitability modeling of available aquatic habitat was performed using MaxEnt, a robust machine learning algorithm. Individual waterbody suitability means were also extracted to rank waterbodies within highly suitable regions. This work revealed that South Dakota possesses widespread suitable …

The Pedagogy Of Legal Synthesis, Stephen Mortellaro

Scholarly Articles

The ability to synthesize implicit legal principles from many ambiguous cases is a mark of a skilled attorney. But legal synthesis is notoriously challenging to teach, and law students typically receive little explicit guidance on how to synthesize. The literature likewise offers law professors little direction on how to impart the skill successfully. This Article serves as a guide for professors to effectively train law students to synthesize implicit legal principles. Drawing upon cognitive science, the study of logic, and educational research, this Article explains the challenges of learning legal synthesis and equips professors with pedagogical methods and curricular resources …

T.H. V. The Czech Republic: A Step Forward Or Back For Lgbtq+ Rights And Discourse In Europe With The First Openly Non-Binary Applicant?, Katherine Olsson

Human Rights Brief

On December 9, 2025, the European Court of Human Rights (ECtHR) issued a final judgment in the case of T.H. v. The Czech Republic.  The case concerned a non-binary individual, T.H., who was assigned male at birth and, since May 2012, had repeatedly petitioned to change their sex/gender marker and personal numerical code on their national identity card.  Because the Czech system does not provide for the option of a neutral gender marker, T.H. petitioned to have their registered gender changed to female.

Corporate Culpability And The Tragedy Of The Commons: Extraction And Enforcement Schemes In Brazil And Nigeria, Jane Ijeoma Onuoha

Emory International Law Review

Natural resources that were abundant decades ago are now at an all-time low. Meanwhile, corporations continue to benefit from using the Earth and its resources for their profit. Rather than enforcing established legal frameworks designed to protect the environment and human rights, governments often allow corruption, control, and competition to create opportunities for gain through complicity. In countries like the Federative Republic of Brazil and in the Federal Republic of Nigeria, the effects of inaction are taking a toll on the natural resources that each country relies on. Multinational corporations are not held accountable for their corrupt and illegal extractive …

From Generation To Generation: Older People And Ageism In Violent Conflict, Alexis Jori Shanes

Case Western Reserve Journal of International Law

Conflicts in every generation disproportionately impact older people. Older people are often unable to exercise their most basic human rights during peacetime, and conflicts only amplify this problem. Despite this reality, international law does not provide specialized protection for older people, and they are often excluded from international justice processes.

International law does not define the term “older,” although the word is often used to describe a group of people roughly age 60 or above. But there is no question that the median age of the global population is rising. Today, there are more than 700 million people older than …

Scaffolding Minimum Age Thresholds, Eve Rips

UIC Law Open Access Faculty Scholarship

No abstract provided.

Evaluation Of Peptides And Peptide–Doxorubicin Conjugates Designed And Synthesized For Targeting Triple-Negative Breast Cancer Via Cell-Surface Receptors, Shih-Jing (Jane) Yao

Pharmaceutical Sciences (PhD) Dissertations

A significant problem faced in oncology is the lack of chemotherapeutic agents that are tumor site-specific, resulting in reduced therapeutic efficacy and unintended infliction of harm to surrounding healthy tissues and cells that often lead to serious side effects. Current strategies being explored to circumvent this issue aim to refine delivery of  chemotherapeutic agents specifically to tumor sites, which may be achieved via conjugation of these agents to biomarker-specific ligands. This forms the foundation of ligand-targeted drug delivery. Among different breast cancers, treatment of the triple-negative breast cancer (TNBC) subtype has been particularly challenging, largely due to the absence of …

Not Like Us: Afro-Germans And The Myth Of The "Germanness", Kahron Gaul Blakley

CISLA Senior Integrative Projects

No abstract provided.

Visible At Last: Legal Recognition Of Children Born Of War (Cbow) And The Case Of Bosnia And Herzegovina, Ajna Jusić, Gordana Subotić Ph.D.

Human Rights Brief

Children born of war (CBOW) — those conceived through conflict-related sexual violence— have long remained stigmatized, marginalized, and largely invisible in law and policy. Drawing on international scholarship and Bosnia and Herzegovina’s post-conflict experience, this Article examines the social, political, and legal mechanisms that sustain CBOW exclusion and traces the emergence of CBOW as a recognized category within contemporary international legal frameworks. Using Bosnia and Herzegovina as a case study, the Article argues that patriarchal norms, fragmented governance and legal structures, and decades of institutional silence have profoundly shaped CBOW lived experiences and access to rights. Furthermore, the Article assesses …

Anticancer Efficacy Of Methyl-Cantharidimide (Mca) In Liver Cancer, Yidong Li

Theses and Dissertations

Cancer is still one of the major public health challenges worldwide to the present day. Multi-drug resistance (MDR) that occurs in cancer chemotherapies is a non-negligible cause of cancer treatment failure and tumor recurrence. Overexpression of ATP-binding cassette (ABC) transporters is one of the most frequent mechanisms of MDR occurrence. Therefore, the establishment of a chemotherapy agent whose anticancer efficacy would not be affected by the overexpression of ABC transporters is in demand. Methyl-cantharidimide (MCA), a cantharidin (CTD) analog, has been approved in China for clinical liver cancer treatment. This study revealed that MCA was efficacious in the ABCB1-, ABCG2-mediated …

Evaluation Of The Mechanism Of Cell Death After Exposure To Amorphous Silicon Dioxide Nanoparticles In Rat Pleural Mesothelial Cells And Golden Syrian Hamsters, Rachel P. Renda

Theses and Dissertations

Amorphous Silicon Dioxide Nanoparticles (SiO2 NPs) are widely used in the industrial processes, chemical, and cosmetics industries. Amorphous SiO2 NPs are abundant in the earth’s crust and can be released into the air through industrial and manufacturing activities. Such particles are overlooked and not as commonly studied when compared to their crystalline counterpart. Amorphous SiO2 NPs are pulmonary toxicants; however, the mechanism of toxicity is uncertain. In the current study, toxicity was assessed using both in vitro and in vivo systems to understand a possible mechanism of cell death. Rat Pleural Mesothelial Cells (RPMCs) were exposed to 50-800 μg/ml SiO2 …

Utilizing A Genetically Diverse Species To Investigate Gene-Drug Interactions And Drug Efficacy, Jerry Nawongbay Gbarlea

Theses and Dissertations

Gene-drug interactions are fundamental to understanding variability in drug response and therapeutic efficacy. In this project, we leverage the natural genetic divergence between ecotype morphs of the blind Mexican cavefish (Astyanax mexicanus) to investigate differential responses to neuroactive compounds—specifically, the convulsant pentylenetetrazol (PTZ) and the anxiolytic Buspirone Hydrochloride. Astyanax Mexicanus is a tetra species consisting of both surface-dwelling (ancestral) and cave-dwelling (mutant) populations that have highly variable genetic backgrounds. Independently evolved populations of cavefish exhibit a suite of convergent traits that can be functionally interrogated to discover new genetic functions and interactions. These attributes make A. mexicanus an ideal model …

Deconstructing Shifting Narratives: Critical Discourse Analysis Of Terminology Trends In Unfpa’S State Of World Population Reports (1978-2024), Naqib A. Noory

Theses and Dissertations

Rooted in both scholarly inquiry and lived experience in global development, this study explored how language shapes power, inclusion, and representation. It analyzed the evolution of population and development discourse in UNFPA’s State of World Population reports (1978–2024) using Fairclough’s Level 1 Critical Discourse Analysis framework. Giddens’ Structuration Theory provided a broader lens linking linguistic change to the interaction between institutional structures and human agency. A theory-based coding framework, drawing on Malthusian, Senian, Spivakian, and MDG/SDG paradigms, guided the analysis of evolving discourse. Findings revealed a layered narrative: earlier scarcity framings persisted beneath newer development language; rights and empowerment rhetoric …

Exploring The Leadership Qualities Of Lgbtq+ School Administrators Through The Prism Of The Developmental Model Of The Closet, Andrew Mcintosh

Theses and Dissertations

This qualitative study explored how LGBTQ+ school administrators perceive the influence of their lived experiences on their leadership qualities. Additionally, this study examined post-closet growth, closet adaptations, and how legal protections influence LGBTQ+ school administrators. A narrative methodology was employed to shed light on the lived experiences of participants. A mix of purposive, convenience, and snowball sampling was used for this study. The researcher recruited school administrators from public school districts and private schools located in the Northeastern United States. School administrators include positions such as assistant principal, principal, assistant superintendent, director, superintendent, and head of school. Eight participants took …

An Exploration Of The Perceptions Of Black Women Leading Interscholastic Sports Programs, Leslie Zeelika Pieters-Klatsky

Theses and Dissertations

The purpose of the study was to examine the perceptions of Black women leading interscholastic sports programs. Prior research examined the underrepresentation of women in sports leadership, but no study has examined prejudice toward the Black woman in an interscholastic sports leadership role. Data were collected through in-depth semi-structured interviews with Black women leading interscholastic athletics, using Kimberlé Crenshaw's intersectionality as a theoretical framework. This study sought to give voice to a select group of women who perceived being barred entry into the white-male-dominated field of interscholastic sports leadership by the Good Old Boys’ Network and the Good Old Girls’ …

Reading Between The Lines: Exploring How Technical High School Teachers Navigate Race And Neurodiversity Through Literacy Practices, Genesis A. Ryant

Theses and Dissertations

This qualitative study employed a hybrid hermeneutic phenomenological design to explore how technical high school teachers experienced and interpreted literacy instruction for Black and Brown neurodivergent students. Grounded in Critical Race Theory (CRT) and Disability Critical Race Theory (DisCrit), the research examined how educators’ perceptions, instructional practices, and collaborative relationships shaped access, equity, and empowerment in career and technical education contexts. Data was collected from seven academic and trade teachers through semi-structured interviews, focus groups, lesson artifacts, and reflective journals. Analysis followed Peoples’ (2020) hermeneutic explication process and Saldaña’s (2021) multi-cycle coding methods, integrating in vivo, process, and axial coding …

In Vitro Investigation Of Myoblasts As A Cell Therapy Candidate And Their Effects On Macrophages, Olivia Armas, Erica Duffy, Arthur Klujian, Clara Markel, Franklin Ng, Elisabeth Stodola

Baker/Koob Endowments Awarded Projects

Human macrophage isolation was successful with a 10% yield. Isolations are being further refined using an autoMACS cell separator, providing students instructional training on industry-level equipment that is commonly used. Through the primary human myoblast and murine macrophage co-culture, a significant shift in phenotype was demonstrated. Macrophage morphology varies with polarization and was used to evaluate the impact of factors and myoblasts at polarizing macrophages. Macrophage morphology was measured using an Image J analysis that quantified the axial ratio of macrophages. Axial ratio was calculated using the major axis divided by minor axis. The results showed that all the pre-polarized …

Chronic In Utero Oxycodone Exposure Alters Placental Small Ev Proteome And Fetal Cardiomyopathy-Linked Pathways, Amin Foroughi Nezhad, Dalia Moore, Victoria L. Schaal, Tousif Ahmed Hediyal, Elizabeth Stone, Sree Kolli, Pranavi Athota, Omar Shukri, Sowmya V. Yelamanchili, Gurudutt Pendyala

Journal Articles: Anesthesiology

Aim: The rising prevalence of opioid use during pregnancy poses serious public health concerns. The placenta is a critical organ during gestation, and opioid exposure can disrupt its function and fetal development. However, the molecular mechanisms through which opioids such as oxycodone affect feto-placental development remain poorly understood. This study aimed to investigate the effects of chronic in-utero oxycodone exposure on the composition and signaling functions of placenta-derived small extracellular vesicles (PSEVs) using a rat model.

Methods: Extracellular vesicles (EVs) were isolated from placental tissue and characterized through nanoparticle tracking analysis, transmission electron microscopy, western blotting, and label-free quantitative proteomics. …

In The Wake Of The Anthropocene: The Ecopoetics Of Shakespearean Film Adaptations, Ioannis Garganourakis

Theses and Dissertations

This dissertation explores how Shakespeare’s plays and their film adaptations reflect and respond to the conditions of the Anthropocene, arguing that both forms of art can foster an environmental ethic attuned to the interconnectedness of human and nonhuman worlds. It proposes that the Anthropocene did not begin with industrialization but rather intensified a much older pattern of human ecological intervention, a process that becomes increasingly visible from the early modern period to the twentieth century. By situating Shakespeare within this expanded temporal framework, this dissertation reveals how his works anticipate and interrogate the very assumptions about anthropocentrism that underpin modern …

The Effects Of Youth Extracurricular Involvement On The Home Environment Of Millennial African American Families, Joyce Merius Speed

Theses and Dissertations

This phenomenological qualitative study explored how youth extracurricular involvement shapes the home environments of Millennial African American families. Guided primarily by Ecological Systems Theory, with Critical Race Theory as a complementary lens, the study examined how parents navigated interconnected systems of home, school, peers, and community while responding to racialized barriers embedded in youth programs. Data were collected through semi-structured interviews, observations, and document analysis with six African American mothers. Seven themes emerged: extracurricular activities, family dynamics, parental involvement, academic achievement, social development, cultural identity, and time management. Findings showed that extracurricular participation strengthened family communication, routines, and cohesion; supported …

The Influence Of Social Media On Elementary School Students: The Perceptions Of Administrators And Elementary Educators, Caitlin Krauszer

Theses and Dissertations

Each day, social media applications are downloaded, uploaded, and changed to meet the users' needs utilizing these apps (Tang & Patrick, 2020). With the constant change in social media platforms, utilization of such platforms is increasing daily and students navigating these platforms is occurring at younger ages (Fredrick at el., 2024; Perez-Chada et al., 2023). This study focused on the social, emotional, and academic impacts students are experiencing due to social media use from the perspectives of building administrators and faculty members. This study also investigated the policies in place within a specific school district that address student social media …

The Yeast Checkpoint Kinase Mec1p Functions In Transcription Termination By Facilitating Recruitment Of Pcf11p And Regulating The Torpedo Exonuclease Rat1p, Riddhi Patel

Theses and Dissertations

My dissertation includes two projects, centered on transcription regulation by checkpoint kinases of the DNA damage response (DDR). The first project focused on the role of checkpoint kinase Mec1p in transcription termination and regulation of the torpedo exonuclease Rat1p. Termination, closely linked with pre-mRNA 3’ processing, dissociates RNA polymerase II (RNAPII) from DNA and releases the nascent RNA transcript. Efficient termination is required for maintaining a pool of RNAPII that is available for re-entry into new transcription cycle. Previous results showed that inactivation of Mec1p in the absence of exogenous genotoxic stress downregulates the efficiency of transcription termination. This study …

Biogothic: New Directions In The Haunted Spaces Of Nineteenth Century Gothic Fiction, Jessica Mintzes

Theses and Dissertations

The BioGothic is a set of biological metaphors in nineteenth century Gothic fiction that anticipates our contemporary understanding of what we now think of as biological processes. The BioGothic system in the novel captures the site of connection and interaction between the body and the interior spaces it inhabits. The Gothic genre, from its inception, shifts the focus onto interior spaces and the ways in which architectural spaces and the Gothic body interact with one another. This demonstrates, in part, how physical space and biological matter are not only capable of becoming integrated with each other, but also maintain the …

Differential Sensitivity Of Leukocyte Populations To Staphylococcus Aureus Biofilm, Nichole D. Brandquist, Tammy Kielian

Journal Articles: Pathology and Microbiology

Staphylococcus aureus is a leading cause of prosthetic joint infection (PJI) typified by biofilm formation. Anti-inflammatory granulocytic myeloid-derived suppressor cells (G-MDSCs) represent the main leukocyte population in a mouse model of S. aureus PJI, followed by neutrophils (PMNs), and macrophages (Mφs), which is also seen during human PJI. Defining how each leukocyte population responds to S. aureus biofilm vs planktonic bacteria could have important implications for how S. aureus evades immune detection to facilitate biofilm persistence. This study compared the kinetics of leukocyte death and relationship to mitochondrial ROS (mtROS) production following exposure to planktonic S. aureus or biofilm. Mφs …

Part Ii: Industrial Information Integration Review 2020-2025, Jinzhi Li

Information Technology & Decision Sciences Faculty Publications

Industrial Information Integration Engineering (IIIE) has become increasingly essential for improving operational efficiency and harmonizing heterogeneous industrial systems through advanced digital integration approaches. Fueled by rapid advancements in Industry 4.0 technologies—including digital twins, artificial intelligence, immersive interfaces, and IoT infrastructures—IIIE is substantially transforming traditional enterprise architecture and integration frameworks. This systematic review synthesizes recent developments and emerging trends, with particular attention to the accelerating adoption of digital twins and the deepening convergence between operational technologies (OT) and information technologies (IT) across multiple sectors. While notable progress has been made, significant challenges persist, especially in developing resilient integration architectures and fully …

Budget For The Fiscal Year Ending June 30, 2026, University Of Arkansas, Fayetteville

Budget for the Fiscal Year

No abstract provided.

Full Issue, Wyoming Law Review Editorial Board

Wyoming Law Review

No abstract provided.