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Articles 11011 - 11040 of 19098
Full-Text Articles in Entire DC Network
Hlt 101 Introduction To Public Health, Elyse Gruttadauria
Hlt 101 Introduction To Public Health, Elyse Gruttadauria
Open Educational Resources
The syllabus, created by Professor Elyse Gruttadauria as part of the CUNY OER Initiatives for HLT 101 contains a course description, course objectives, course readings divided by week and a link to four OER textbooks.
Exposome In Relation To Psychopathology And Physical Pain In Adolescence, Alexsia E. Newman
Exposome In Relation To Psychopathology And Physical Pain In Adolescence, Alexsia E. Newman
Honors Scholar Theses
The overall well-being of adolescents is dependent on a variety of factors during development, including both mental and physical health. Mental health, or psychopathology, which includes internalizing and externalizing problems, represents a common and persistent concern among youth. Physical pain is another important aspect of adolescent well-being. Although prior research has examined associations between mental health and pain, less is known about how these relationships unfold over time, and few studies have considered the role of multilevel environmental factors. This honors thesis explores the predictability and bidirectionality of mental health and chronic pain in developing adolescents, and tests associations of …
The Cowl - V. 89 N. 17 - April 1, 2026
The Cowl - V. 89 N. 17 - April 1, 2026
The Cowl
The Cowl - student newspaper of Providence College. Vol. 89 No. 17 - April 1, 2026. 20 pages.
Small Jellyfish, Large Consequences: The Overlooked Predatory Role Of Hydromedusae In Subtropical Estuarine Ecosystems, Guilherme M. Von Montfort, Kelly R. Sutherland, Sean Colin, John H. Costello, Renato M. Nagata
Small Jellyfish, Large Consequences: The Overlooked Predatory Role Of Hydromedusae In Subtropical Estuarine Ecosystems, Guilherme M. Von Montfort, Kelly R. Sutherland, Sean Colin, John H. Costello, Renato M. Nagata
Arts & Sciences Faculty Publications
Hydromedusae are often overlooked in pelagic trophic ecology compared to large scyphozoans. We investigated the diet, prey selectivity, ingestion rates, digestion times, and predation impacts of the native Liriope tetraphylla and non-indigenous species Cnidostoma fallax and Moerisia inkermanica in a subtropical estuary of the southwestern Atlantic. While all three species predominantly consumed copepods, L. tetraphylla exhibited the broadest diet and highest number of preys in gut content (up to 13). Digestion time for L. tetraphylla decreased significantly with increasing temperature, from 94 min at 18°C to 64 min at 28°C, with Q10 values showing that digestion rates roughly double with …
Discovery And Genome Annotation Of Tuti And Charminar: Two Newly Discovered Gordonia Rubripertincta Bacteriophages
Undergraduate Student Symposium
As the most abundant organisms, bacteria are both beneficial and harmful, highlighting the significance of regulating their growth. Bacteriophages (phages) are ubiquitous viruses that require a host bacterial organism for replication, making them an essential component of the microbial ecosystem and used as tools for killing bacteria. Since their discovery in 1915, phages have been used in real-world applications including alternatives to antibiotics, diagnostic agents, pest control in agriculture, wastewater treatment, and bioremediation. Since bacteriophages remain mostly undiscovered, continued isolation and genetic characterization of novel phages are essential for advancing scientific knowledge and potential applications. Through Nova Southeastern University's SEA-PHAGES …
Exercise As An Intervention Against Neuroinflammation During Binge Drinking Withdrawal, Shaina Binu, Ellie Wind, Ariana Hernandez, Iliana Uribe, Victoria Pulido-Correa
Exercise As An Intervention Against Neuroinflammation During Binge Drinking Withdrawal, Shaina Binu, Ellie Wind, Ariana Hernandez, Iliana Uribe, Victoria Pulido-Correa
Undergraduate Student Symposium
Binge drinking, a public health concern in the United States, is associated with negative emotional and cognitive effects during alcohol withdrawal. These effects are believed to result from changes in brain regions involved in stress regulation, emotion, and decision-making, including the prefrontal cortex, amygdala, and hippocampus. Alcohol exposure has been shown to increase neuroinflammation in these regions, which may contribute to anxiety-like behaviors and difficulty regulating emotions during withdrawal. In contrast, aerobic exercise is a promising non-pharmacological intervention that has been shown to reduce anxiety and support brain health. This project investigates how exercise can reduce withdrawal-related anxiety-like behaviors, following …
Transcranial Magnetic Stimulation For Substance Use Disorder, Sarah Defrant
Transcranial Magnetic Stimulation For Substance Use Disorder, Sarah Defrant
Undergraduate Student Symposium
This review evaluates transcranial magnetic stimulation (TMS) as a supplemental intervention for decreasing substance use disorder (SUD) relapse rates by synthesizing understandings of neurobiological mechanisms and clinical outcomes. TMS stimulates the activity of neural cells in the dorsolateral prefrontal cortex (DLPFC), a small portion of the prefrontal cortex that houses impulse control and decision-making skills. This leads to improved neuroplasticity and dopamine regulation, both of which are disrupted by unregulated substance use. Although TMS is not FDA-approved for substance use disorder, the neurobiological similarities between SUD and its comorbidities like major depressive disorder or anxiety highlight TMS's theoretical potential to …
Proximal Power Gains In Football: Position-Specific Adaptations Revealed Through Compositional Data Analysis, Isabella Estrada Hernandez, Alyana Andal
Proximal Power Gains In Football: Position-Specific Adaptations Revealed Through Compositional Data Analysis, Isabella Estrada Hernandez, Alyana Andal
Undergraduate Student Symposium
Training-induced adaptations in joint power distribution during speed running may enhance performance, but how these changes manifest across different American football position groups remains poorly understood. We investigated the influence of training and player position on joint power composition among players training for the National Football League draft. Forty-eight draft-eligible players performed pre- and post-training camp running trials at 23.4 km/h. We used motion capture software and MATLAB to calculate bilateral peak hip, knee, and ankle joint power. Compositional data analysis (CoDA) was used, in which positive/generated and negative/absorbed power compositions were expressed as isometric log-rations: hip versus knee + …
Baseline Emotional Valence Predicts Subsequent Executive Function Task Performance, Andrea Fajardo Aguilar, Alyssa Harris, Isidora Varas-Sanchez, Julia Ribeiro, Dylan Kuni
Baseline Emotional Valence Predicts Subsequent Executive Function Task Performance, Andrea Fajardo Aguilar, Alyssa Harris, Isidora Varas-Sanchez, Julia Ribeiro, Dylan Kuni
Undergraduate Student Symposium
Executive functioning (EF) supports goal-directed behavior and is influenced by affective state. While prior research has largely focused on the effects of emotional valence during task performance, less is known about the influence of pre-task self-reported valence on subsequent EF performance. Our ongoing study will examine whether self-reported ratings of emotional valence assessed prior to the start of a task will predict performance. Participants will report valence ratings during a resting baseline period before performing two EF tasks: the Vertical Stroop and the Go/No-Go. Performance will be assessed using reaction time and accuracy. Regression analyses will be conducted to …
Comparison Of Bacteria From Varied Soils With Potential Antimicrobial Activity, Nicole Nesterovitch, Nyobi Fleming, Andrew Sourial
Comparison Of Bacteria From Varied Soils With Potential Antimicrobial Activity, Nicole Nesterovitch, Nyobi Fleming, Andrew Sourial
Undergraduate Student Symposium
Antibiotic resistance is increasing at a rate that surpasses the discovery and development of new antimicrobial compounds, creating a widening resistance-innovation gap that poses a global public health concern. To address this need for new antibiotic-producing organisms, we partnered with Tiny Earth, a global initiative that engages students in antibiotic discovery through soil sample collection, bacterial isolation, and antimicrobial screening. We isolated bacteria from local soil in Davie, Florida as well as soil from the White River Badlands, South Dakota with the hypothesis that distinct soil conditions may yield different antimicrobial producers with varied activity and chemical profiles. 42 unique …
Assessing Recovery In Collegiate Swimmers Through Wearable Technology, Sara Quintero
Assessing Recovery In Collegiate Swimmers Through Wearable Technology, Sara Quintero
Undergraduate Student Symposium
Collegiate swimmers face extreme physiological demands during high-intensity training phases like "Hell Week," a winter training intensive loading microcycle, that makes recovery monitoring critical for maintaining performance. This study investigated the relationship between sleep quality and recovery markers. Specifically, Heart Rate Variability (HRV) and Resting Heart Rate (RHR), in nine female collegiate swimmers (ages 19-23) across all collegiate years. Participants included sprinters, mid-distance, and distance swimmers, leading to varied total yardage across training groups. Over an eight-day period (seven training days and one rest day), data was collected via screenshots from Garmin (n=4) and WHOOP (n=5) wearable devices. Metrics included …
Developing New Digital Methods To Study And Improve Eyewitness Testimony, Isabella Ryan, Brianna Munoz, Adam Durnin, Tanya Schrader, Joana Vinagre
Developing New Digital Methods To Study And Improve Eyewitness Testimony, Isabella Ryan, Brianna Munoz, Adam Durnin, Tanya Schrader, Joana Vinagre
Undergraduate Student Symposium
Witnesses play a crucial role in criminal investigations. However, their ability to recall important details is influenced by cognitive processes such as memory. To improve eyewitness testimony, psychologists developed science-based interviewing techniques, such as the Cognitive Interview, which are used by police to elicit accurate accounts. We also created new retrieval strategies, namely the Category Clustering Recall (CCR), which has been implemented by agencies such as the Los Angeles Police Department. However, research supporting the use of these techniques predominantly used the mock-witness paradigm, where participants observed a mock-crime on a two-dimensional (2D) screen and recalled it in a controlled …
Group Differences In Conflict Processing Between Bilinguals And Monolinguals, Isidora Varas-Sanchez, Dylan Kuni, Julia Ribeiro, Andrea Fajardo Aguilar, Alyssa Harris
Group Differences In Conflict Processing Between Bilinguals And Monolinguals, Isidora Varas-Sanchez, Dylan Kuni, Julia Ribeiro, Andrea Fajardo Aguilar, Alyssa Harris
Undergraduate Student Symposium
There is an ongoing debate in the literature on the existence of a bilingual advantage on tests of attention. Hypothetically, bilinguals have an advantage over monolinguals on tests of attention because both attention and language control share the same inhibitory mechanism. Because bilinguals engage this mechanism more often than monolinguals, inhibitory control is believed to be stronger and confer an advantage. However, research findings on the bilingual advantage are inconsistent and attempts to reproduce prior results have sometimes failed. The argument is that studies may have failed to capture the important aspects of language linked to attention. Prior research from …
Interventions For Reducing Barriers To Future Employment Success In First-Generation College Students., Kellie M. Burke
Interventions For Reducing Barriers To Future Employment Success In First-Generation College Students., Kellie M. Burke
Doctor of Social Work Capstone Projects
First-generation college students (FGCS) comprise a significant and diverse segment of the U.S. undergraduate population, yet they remain disproportionately vulnerable to barriers that impede both academic achievement and career advancement. These challenges, rooted in intersecting factors (e.g., race & gender), are amplified by institutional structures that inadequately address the realities faced by FGCS. Despite the proliferation of career development programs, internship participation, and subsequent employment, among FGCS remains notably low, revealing persistent gaps in support, access, and program efficacy.
This qualitative study evaluates the Rising Leaders Program, an agency-driven intervention designed to promote career readiness for FGCS at Kentucky universities …
Alternative Anticoagulation Strategies For Heparin-Intolerant Patients Undergoing Cardiopulmonary Bypass: A Scoping Review Of Patient Outcomes, Zachary Nelson
Alternative Anticoagulation Strategies For Heparin-Intolerant Patients Undergoing Cardiopulmonary Bypass: A Scoping Review Of Patient Outcomes, Zachary Nelson
Student Works
Background/Introduction: Heparin intolerance, most notably heparin-induced thrombocytopenia (HIT), presents a major clinical challenge during cardiopulmonary bypass (CPB), where systemic anticoagulation is essential for safe circulation through the extracorporeal circuit. While several alternative anticoagulants have been described, there is limited consensus regarding their safety, dosing, and outcomes. The objective of this study was to map existing evidence describing alternative anticoagulation strategies for heparin-intolerant adult patients undergoing CPB and to summarize reported patient outcomes, dosing strategies, and intraoperative management considerations.
Methodology: This scoping review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) …
Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley
Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley
Markey Cancer Center Faculty Publications
Background: Almost all correlation measures currently available are unable to directly handle missing values. Typically, missing values are either ignored completely by removing them or are imputed and used in the calculation of the correlation coefficient. In either case, the correlation value will be impacted based on the perspective that the missing data represents no useful information. However, missing values occur in real datasets for a variety of reasons. In metabolomics datasets a major reason for missing values is that a specific measurable phenomenon falls below the detection limits of the analytical instrumentation (left-censored values). These missing data are not …
Mapping The Polar Neuro-Interactome Of Garcinia Mangostana Against The Ad-Pd-Als Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, Jitbanjong Tangpong
Mapping The Polar Neuro-Interactome Of Garcinia Mangostana Against The Ad-Pd-Als Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, Jitbanjong Tangpong
Markey Cancer Center Faculty Publications
Background/Objectives: Neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Amyotrophic lateral sclerosis (ALS) share common molecular pathways, including neuroinflammation and oxidative stress, which complicate the effectiveness of single-target treatments. Garcinia mangostana L. (mangosteen) has shown neuroprotective properties, but previous studies focused on lipophilic xanthones, which have poor bioavailability and uncertain blood–brain barrier permeability. Methods: In the current study, polar metabolites from G. mangostana peel aqueous extract (GMPE) were assessed for potential multi-target interactions via UHPLC-QTOF-MS-based metabolomics, systems pharmacology, and molecular docking analysis. Further, in silico ADMET screening and network-based analyses assessed for overlap between GMPE compounds and genes associated with neurodegeneration (AD, …
Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath
Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath
Markey Cancer Center Faculty Publications
Age-related cellular changes negatively impact CD4+ T cell function. Our prior work showed that mitochondrial complex II (succinate dehydrogenase [SDH]) expression was upregulated in T cells from older (O) adults (60–80 years old). T cells from older adults also produced higher amounts of cytokines generally considered proinflammatory, such as Th17 cytokines IL-17A/F and IL-21, and the Th-17-supportive cytokine IL-6, compared to T cells from younger (Y) adults (25–40 years old). The objective of our study is to evaluate whether hyperactivation of SDH is required for the induction of proinflammatory cytokines and the mechanistic link between SDH and Th17 cytokine …
Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann
Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann
Markey Cancer Center Faculty Publications
Chronic ethanol (EtOH) consumption is a major contributor to multi-organ dysfunction, yet its systemic effects remain incompletely understood. To address this, we utilized a physiologically relevant long-term mouse model, administering 20% EtOH in drinking water for 60 weeks, to investigate the integrated consequences of chronic exposure. EtOH-consuming mice (0.4–0.5 mL/day) exhibited > 30% reductions in chow and fluid intake, resulting in a 12% decrease in total caloric intake compared to controls (p < 0.001). Body mass remained similar until Week 52, after which EtOH-treated mice had lower body mass due to reductions in both lean and fat mass (p ≤ 0.004). Functional assessments revealed impaired treadmill endurance (−17%) and grip strength (−11%) (p ≤ 0.037), while motor coordination remained unaffected (p = 0.203). Chronic EtOH exposure significantly altered gut microbiota composition, reducing Lactobacillus and enriching Faecalibaculum, Clostridium, and Bifidobacterium at the genus level. These changes were accompanied by marked depletion of short-chain fatty acids (p ≤ 0.05). Indirect markers of gut permeability (serum LPS & zonulin) and liver injury (serum ALT & AST, hepatic amyloid content) were elevated, alongside increased total cholesterol and > 62% upregulation of hepatic TNFα, IL-6 & serum amyloid A (p ≤ 0.046). EtOH also induced dyslipidemia and glucose intolerance (p ≤ 0.041), although transcriptomic changes in white adipose …
Embodied Horror: Women And Medical Authority In Video Games, Jocilynn Denise Colombo
Embodied Horror: Women And Medical Authority In Video Games, Jocilynn Denise Colombo
Comparative Literature M.A. Essays
Through a critical analysis of interactive horror, this paper argues that video games can function as ethical diagnostic narratives that uniquely expose systemic failures surrounding women’s bodies and medical authority. Focusing on Silent Hill 3 (2003) and Alice: Madness Returns (2011), I examine how these games render harm legible through player participation. By requiring players to move characters through hostile environments and make decisions within systems that simultaneously grant and restrict control, these games foster identification and complicity by positioning players directly within the structures they critique.
While feminist horror scholarship—notably from Julia Kristeva and Barbara Creed—has explored societal anxieties …
The Transparent Crypt: Temporal Stratification, Materiality, And The Affective Archive In Jenny Erpenbeck’S "Kairos", Mallory Wooldridge
The Transparent Crypt: Temporal Stratification, Materiality, And The Affective Archive In Jenny Erpenbeck’S "Kairos", Mallory Wooldridge
Comparative Literature M.A. Essays
For Germany, the process of reckoning with the past is not a new one. Termed Vergangenheitsbewältigung in the post-war period and envisioned as a project extending beyond the academy into public consciousness, “dealing with the past” was first envisioned in response to the Nazi regime and its horrors. While already a disjointed project in the Nazi context, the question of how reunified Germany reckons with the former German Democratic Republic’s past remains unresolved.
In her 2021 novel Kairos, Jenny Erpenbeck proposes a different model of historical consciousness. Drawing on Theodor Adorno’s post-war theory of working through the past ( …
Beyond Parallel Programmes: A Roadmap For Operational Integration Of Family Planning And Nutrition In Low- And Middle-Income Countries, Marleen Temmerman, Samuel Ojong
Beyond Parallel Programmes: A Roadmap For Operational Integration Of Family Planning And Nutrition In Low- And Middle-Income Countries, Marleen Temmerman, Samuel Ojong
Centre of Excellence in Women and Child Health
No abstract provided.
World Health Organization Classification Of Tumours Of The Breast 6th Edition 2026, Cecily Quinn, Puay Tan, Kimberly Allison, Edi Brogi, Sunil Lakhani, Stuart Schnitt, Stephen Fox, Shabnam Jaffer, Aysegul Sahin, Shahin Sayed
World Health Organization Classification Of Tumours Of The Breast 6th Edition 2026, Cecily Quinn, Puay Tan, Kimberly Allison, Edi Brogi, Sunil Lakhani, Stuart Schnitt, Stephen Fox, Shabnam Jaffer, Aysegul Sahin, Shahin Sayed
Pathology, East Africa
The 6th edition of the WHO Classification of Breast Tumours introduces both major and minor changes based on recent advances in our understanding of breast biology, developments in diagnostic modalities, identification of specific molecular targets and new treatment regimens necessitating modifications to pathology reporting and tumour biomarker categorisation. This review summarises the main changes that strive towards a classification of global relevance. In invasive carcinoma, predictive factors increasingly inform modern breast cancer treatment. The 6th edition provides an update on HER2 reporting categories following the DESTINY-Breast 04 and 06 trials. Terminologies used to classify invasive tumours are clarified, with the …
From Ancient Harmony To Modern Sustainability: Assessing The Coupling Of Taoist “Harmony Between Humanity And Nature” With Esg And Its Impact On Firm Innovation And Performance, Biyi Wang
Dissertations and Theses Collection (Open Access)
Against the backdrop of intensifying global ecological crises, the ESG evaluation system has become a core metric for corporate sustainable development worldwide. However, the Western-dominated ESG system lacks crucial cultural dimensions in its application within Chinese corporate practices. The ecological wisdom embedded in the Taoist concept of “Harmony between Humanity and Nature” offers a significant philosophical foundation for the ESG localization. Extant research has focused on the influence of Confucian culture on ESG, with insufficient exploration of the modern managerial value of “Harmony between Humanity and Nature”. A scientific coupling framework linking this concept with ESG indicators has yet to …
Beyond The Script: A Qualitative Study Exploring Drama Teachers’ Experiences Using Improvisation In Chicago Public Schools, Nicole Theresa Minardi
Beyond The Script: A Qualitative Study Exploring Drama Teachers’ Experiences Using Improvisation In Chicago Public Schools, Nicole Theresa Minardi
Theses and Dissertations from DePaul University
Scripted and standardized curricula remain prevalent in American classrooms. Relying on an authoritarian view of education, in which the teacher imparts knowledge to students, scripted curricula can delegitimize the teaching profession, stifle dialogue, and limit student engagement. Conversely, decentering the teacher can create space for more collaborative and engaged learning. This basic interpretive qualitative study explored how Chicago Public Schools drama teachers described their experiences incorporating improvisation into their instruction. Grounded in critical pedagogy and a social constructivist epistemology, this study examined how drama teachers currently use improvisation in their classrooms, as well as the benefits and challenges they encounter …
Technostress, Worker Wellbeing, And Ethics: An Integrative Review, Mackenzie Moreno
Technostress, Worker Wellbeing, And Ethics: An Integrative Review, Mackenzie Moreno
Theses and Dissertations from DePaul University
Rapid advances in workplace technologies have led to increasing concerns about technostress and its implications for worker health and wellbeing. While the technostress literature has at times addressed psychological and physiological wellbeing outcomes, these outcomes have not been examined consistently, and explicit integration of ethics is largely absent. This integrative review addresses these gaps by synthesizing empirical findings on how technostress impacts worker health and wellbeing, and by examining the extent to which ethical considerations are integrated into the extant literature. Drawing on these findings, the review proposes a theoretical model of technostress mechanisms. Finally, it summarizes organizational recommendations for …
The Perceptions Of Early Adolescents: Academic Stressors Within Under-Resourced Schools, Problem Solving, And Important Adults, Aliyah White
The Perceptions Of Early Adolescents: Academic Stressors Within Under-Resourced Schools, Problem Solving, And Important Adults, Aliyah White
Theses and Dissertations from DePaul University
Early adolescence is marked by increasing academic demands and the growing need for effective coping strategies. The present study examined early adolescents’ perceptions of academic stressors, use of primary control coping mechanisms, and identification of important related and unrelated adults within their lives. Participants included 96 youth ages 10-14 recruited from Chicago Public Schools in under-resourced South Side communities. Results indicated that youth reported substantial exposure to academic stressors, including teachers yelling, difficulties understanding coursework, and pressure to perform well academically. Findings revealed a significant decrease in the use of primary control coping strategies over time, despite increasing academic stress. …
The Impact Of Social Support On Somatic Health Symptoms In Emerging Adults: Examining The Role Of Cortisol And Cytokines, Autumn Sharon Rajcevich Schwer
The Impact Of Social Support On Somatic Health Symptoms In Emerging Adults: Examining The Role Of Cortisol And Cytokines, Autumn Sharon Rajcevich Schwer
Theses and Dissertations from DePaul University
There is a wealth of previous research demonstrating that increased levels of social support are associated with mental health benefits, with several potential pathways supported, including social support leading to increased emotional comfort and resilience (Mohan et al., 2024). However, research also demonstrates that increased social support is associated with numerous physical health benefits as well, including lowered risk of chronic disease development and longer lifespans (Hale et al., 2005). But there seems to be a gap in research regarding how social support creates this positive physiological effect. The present study aimed to address this gap and investigate the potential …
The Impact Of Estrogen Replacement During Perimenopause On Lung Function And Airway Inflammation In The Vcd Mouse Model, William P Pederson, Laurie Michelle Ellerman, Riley D Hellinger, Joselyn Joanna Rojas Quintero, Francesca Polverino, John P Konhilas, Julie G Ledford
The Impact Of Estrogen Replacement During Perimenopause On Lung Function And Airway Inflammation In The Vcd Mouse Model, William P Pederson, Laurie Michelle Ellerman, Riley D Hellinger, Joselyn Joanna Rojas Quintero, Francesca Polverino, John P Konhilas, Julie G Ledford
Faculty, Staff and Students Publications
Background:
Menopause associated asthma impacts a subset of women and is less responsive to current treatments. Mechanisms driving this late onset asthma are unknown. We recently developed a mouse model of menopause associated asthma using a combination of 4-Vinylcyclohexene Diepoxide (VCD) and House Dust Mite (HDM) exposures. The goal of this study was to determine how hormone replacement therapy during perimenopause impacts lung function and inflammation.
Methods:
The experimental groups included menopausal mice (VCD) with and without exposure to HDM (to model allergic airways disease) and menopausal mice with and without hormone replacement therapy (HRT; via estrogen pellet implantation). Lung …
A Comprehensive Review Of Tear Fluid Proteome Alterations In Dry Eye Disease: Insights Into Pathophysiology And Biomarker Potential, Saleh Ahmed, Steven Safille, Victoria Clifton, Shruti Sharma, Cintia S De Paiva, Ashok Sharma
A Comprehensive Review Of Tear Fluid Proteome Alterations In Dry Eye Disease: Insights Into Pathophysiology And Biomarker Potential, Saleh Ahmed, Steven Safille, Victoria Clifton, Shruti Sharma, Cintia S De Paiva, Ashok Sharma
Faculty, Staff and Students Publications
Tear fluid is a highly specialized and dynamic biofluid composed of proteins, lipids, mucins, and electrolytes that is essential for maintaining ocular surface integrity, immune defense, and tear film stability. Growing evidence from tear proteomic studieshas revealed extensive alterations in protein composition in dry eye disease (DED), reflecting a complex interplay between local ocular surface pathology and systemic inflammatory influences. This review summarizes proteomic findings from 50 published studies to identify tear proteins that are consistently upregulated or downregulated in DED and to interpret their biological relevance in the context of ocular surface homeostasis. Across studies, proteins upregulated in DED …