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Articles 1501 - 1530 of 6821
Full-Text Articles in Entire DC Network
Hormonal Shifts And Structural Strain: A Literature Review Of Menopause And Perimenopause In Relation To Overuse Injuries And Stress Fractures, Mustafa Ansari, Faisal Hussain, Mutasem Shopon, Hanfa Ajmal, Mueez Asif, Sharon David
Hormonal Shifts And Structural Strain: A Literature Review Of Menopause And Perimenopause In Relation To Overuse Injuries And Stress Fractures, Mustafa Ansari, Faisal Hussain, Mutasem Shopon, Hanfa Ajmal, Mueez Asif, Sharon David
Student Publications
Musculoskeletal injury risk in midlife women has traditionally been attributed to estrogen decline, but this narrow focus overlooks the broader biomechanical, neuromuscular, and structural changes associated with menopause. Estrogen plays a multisystem role in maintaining trabecular bone integrity, collagen turnover, and neuromuscular coordination. Its abrupt loss causes bone demineralization (2%-5% annually in early menopause), impairs tendon repair, and contributes to sarcopenia. Fluctuating estradiol levels during perimenopause may transiently increase ligament laxity, further destabilizing joints. Common injuries such as Achilles and rotator cuff tendinopathies, plantar fasciitis, and stress fractures are amplified by low bone mineral density, prior fracture history, aromatase inhibitor …
Across Borders, Across Cultures: A Quest For Health And Well-Being Portfolio, Carrington Connor
Across Borders, Across Cultures: A Quest For Health And Well-Being Portfolio, Carrington Connor
UN SDG Open Pedagogy Faculty Fellowship: Renewable Assignments
No abstract provided.
Social Media And Health Information Sharing In Nigeria: Trends In Weight Loss And Cosmetic Procedures, Victoria Ochanya Agbo
Social Media And Health Information Sharing In Nigeria: Trends In Weight Loss And Cosmetic Procedures, Victoria Ochanya Agbo
Student Theses and Dissertations
This study examines the role of social media in facilitating (mis)information on weight loss and cosmetic surgeries in Nigeria. Utilizing the Elaboration Likelihood Model (ELM), the study examines information shared by influencers, audience engagements with such messages, and the factors influencing audience receptivity of the messages. Using a qualitative design, a thematic analysis was conducted on influencer posts and audience responses to such posts across major social media platforms. The findings show that influencers frequently framed cosmetic surgery and weight loss as aspirational lifestyle choices and downplayed the medical risks using means such as testimonials, visual transformations, and authenticity cues. …
The Transitional Liver Clinic: Study Protocol For A Stepped-Wedge Cluster Randomized Trial, Lindsay Yoder, Elliot B. Tapper, Richard S. Kalman, Mary Rinella, Nicole Bendin, Manisha Verma, Francis Pike, Naga Chalasani, Neha Nalumasu, Eric S. Orman
The Transitional Liver Clinic: Study Protocol For A Stepped-Wedge Cluster Randomized Trial, Lindsay Yoder, Elliot B. Tapper, Richard S. Kalman, Mary Rinella, Nicole Bendin, Manisha Verma, Francis Pike, Naga Chalasani, Neha Nalumasu, Eric S. Orman
Einstein Health Papers
BACKGROUND: Patients with complications of advanced liver disease experience high rates of hospital readmission after discharge. Transitional care models have improved outcomes in other chronic conditions, but their efficacy in liver disease care remains uncertain. This randomized trial evaluates the effectiveness of a tailored transitional care model-the Transitional Liver Clinic (TLC)-in reducing readmissions, improving quality of life, and enhancing patient satisfaction for patients with advanced liver disease.
METHODS: This is a 45-month, stepped-wedge cluster randomized trial enrolling up to 1000 patients with advanced liver disease across 4 academic medical centers. Each site transitions from usual care to the TLC intervention …
Natural Behavior Vs. Subjective Experience In Fish Welfare Assessments, Ronald G. Oldfield
Natural Behavior Vs. Subjective Experience In Fish Welfare Assessments, Ronald G. Oldfield
Animal Sentience
Several commentaries on the Oldfield & Bonano (2024) target article proposed that natural behavior should play a larger role in assessing the welfare of fishes in zoos and aquariums. However, the natural-behavior concept of animal welfare has been widely criticized because natural behaviors do not necessarily improve welfare, and unnatural behaviors do not necessarily reduce it. I review the three major concepts of animal welfare — physical health, natural behavior, and affect/feelings — and argue that behavior patterns, whether natural or otherwise, should be evaluated according to their effects on health and subjective experience. Using the affect/feelings concept and the …
Assessing Rural Homelessness: A Mixed-Methods Case Study, Matthew J. Lyons
Assessing Rural Homelessness: A Mixed-Methods Case Study, Matthew J. Lyons
Faculty Articles
Rural homelessness represents a significant public health and human rights challenge, but research on homelessness in the United States has predominantly focused on urban settings. This case study describes a mixed-methods assessment of the prevalence, causes, and consequences of homelessness in a rural county. Through both surveys and interviews with stakeholders from multiple sectors (including both service providers and those experiencing homelessness), we built a rich picture of the scale and experiential dimensions of homelessness within the county. Here, we present our research methods, the main findings of each primary data collection arm, and the actionable conclusions drawn from the …
Fear Of Negative Evaluation And Intrinsic Motivation In Resistance-Trained Individuals: A Comparison Of Novice And Experienced Lifters, Karter Bokker
Fear Of Negative Evaluation And Intrinsic Motivation In Resistance-Trained Individuals: A Comparison Of Novice And Experienced Lifters, Karter Bokker
Student Theses and Dissertations
This study examined the relationship between fear of negative evaluation (FNE) and intrinsic motivation in resistance-trained individuals and compared FNE levels between novice and experienced lifters. Twenty-two male participants (n = 8 novices, n = 14 experienced) completed questionnaires assessing FNE and intrinsic motivation. A Pearson correlation and independent-samples t-test were conducted. Results indicated no significant relationship between FNE and intrinsic motivation (r = -.144, p = .523). However, novice lifters reported significantly higher FNE scores than experienced lifters, (t20) = 2.71, p = .014, with a large effect size (d = 1.20). These findings suggest that while FNE may …
Lived Experiences Of Competency-Based Grading: Implementation In The Secondary Public School Setting, Andrew Robbins Gillespie
Lived Experiences Of Competency-Based Grading: Implementation In The Secondary Public School Setting, Andrew Robbins Gillespie
Student Theses and Dissertations
The implementation of non-traditional grading systems is a current theme in American public school education. Competency-Based Grading (CBG) is a system that many school districts are considering. CBG is based on essential learning objectives and streamlines the grading of those objectives. CBG also removes high stakes assessment by allowing reassessment. However, studies have shown implementation efforts are often met with obstacles for either a lack of preparation or understanding. This dissertation seeks to understand the lived experiences of educational staff with the CBG implementation process through a phenomenological study. Data was gathered through interviews, observations, and document review. The themes …
Bridging Cultural Gaps In Enhancing Mental Health Support For The Bhutanese Community, Subash Chandra Majhi
Bridging Cultural Gaps In Enhancing Mental Health Support For The Bhutanese Community, Subash Chandra Majhi
Walden Dissertations and Doctoral Studies
No abstract provided.
Artificial Intelligence In Hospital Pharmacy Practice: Effectiveness, Internal Validity, And Translational Readiness: A Systematic Review, Kwanchai Rattanamanee, Parnupong Kiewsiri, Prayuth Poowaruttanawiwit
Artificial Intelligence In Hospital Pharmacy Practice: Effectiveness, Internal Validity, And Translational Readiness: A Systematic Review, Kwanchai Rattanamanee, Parnupong Kiewsiri, Prayuth Poowaruttanawiwit
The Thai Journal of Pharmaceutical Sciences
Background: Artificial intelligence (AI) is increasingly integrated into hospital pharmacy, offering potential to enhance medication safety, therapeutic decision-making, and operational efficiency. However, the internal validity and translational readiness of current interventions remain uncertain.
Objectives: The objective of the study was to systematically review AI applications in hospital pharmacy and evaluate their effectiveness, internal validity, and readiness for clinical integration.
Methods: Following Preferred Reporting Items for Systematic reviews and Meta-Analyses 2020 guidelines and PROSPERO registration (CRD420251067936), We systematically searched PubMed, Embase, Scopus, Web of Science, IEEE Xplore, and ThaiJO (2000–June 2025). for randomized controlled trials (RCTs), cohort, quasi-experimental, and case–control studies …
Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal
Contribution Of Animals To Biomedical Advancements In The Current Era: A Narrative Review, Leena Rajathy Port Louis, Mani Rajarathinam, Prithiviraj Nagarajan, Divya Sekar, Nisha Perumal
The Thai Journal of Pharmaceutical Sciences
Animal research has played a major role in the development of vaccinations and therapies for illnesses such as tetanus, polio, meningitis, hepatitis, and Severe Acute Respiratory Syndrome Coronavirus 2. For every prescription drug available today, animal testing and research have contributed immensely. This narrative review aims to explore the contribution of animals to biomedical advancements in the current era, which involved a search of peer-reviewed literature using electronic databases such as Scopus, Web of Science, and PubMed. In current biomedical research, animals help develop new treatments for long-term illnesses such as cancer, HIV, and Alzheimer’s. Animals also aid in the …
Using Phenomenology To Investigate Digital Experience: An Empathic-Somatic Approach, Bismark Wiafe Bimpong, William Kesse Bimpong, Mercy Egyir Kwakye
Using Phenomenology To Investigate Digital Experience: An Empathic-Somatic Approach, Bismark Wiafe Bimpong, William Kesse Bimpong, Mercy Egyir Kwakye
Mid-Western Educational Researcher
This conceptual paper proposes the Empathic-Somatic Approach as a methodological contribution for conducting phenomenological research on digital technology experiences. The Empathic-Somatic Approach does not replace existing phenomenological methods but enriches them by operationalizing the insight that we understand others through our own bodies as instruments of empathy. The paper first establishes the essential philosophical and methodological foundations of phenomenology needed to situate this contribution, then develops the Empathic-Somatic Approach in detail, and finally provides practical guidance for its implementation in digital technology research. This approach offers researchers in fields such as human-computer interaction, digital health, and information systems a principled …
When The Weeds Strike Back: Rethinking Aphis's Regulation Of Genetically Engineered Plants Post-National Family Farm Coalition V. Vilsack, Reagan Powers
Tennessee Journal of Law and Policy
No abstract provided.
Racial Justice And The Image Of Public Health, Marilyn Fischer
Racial Justice And The Image Of Public Health, Marilyn Fischer
Dewey Studies
No abstract provided.
Knowledge, Attitude, And Practice Regarding Vitamin D Among Adults In Western Libya: Assessment And Socio-Demographic Influences, Abdounasser Albasher Omar, Kawther Adaila, Mofida M. Alfaid, Abdurrahman M Sweidan, Ruqayah Kasheem, Samia Emhemmed Abadi, Abdulnabi Ali Abushita, Hafsa A. Alemam
Knowledge, Attitude, And Practice Regarding Vitamin D Among Adults In Western Libya: Assessment And Socio-Demographic Influences, Abdounasser Albasher Omar, Kawther Adaila, Mofida M. Alfaid, Abdurrahman M Sweidan, Ruqayah Kasheem, Samia Emhemmed Abadi, Abdulnabi Ali Abushita, Hafsa A. Alemam
Al-Bahir
Vitamin D deficiency is a widespread public health concern, necessitating a clear understanding of knowledge, attitudes, and practices (KAP) among populations. Therefore, this study was conducted to assess Libyan citizens' knowledge, attitude, and practice (KAP) regarding vitamin D in the western region of Libya. This study was carried out between June and September of 2021. A questionnaire was distributed across the study area and the complete responses were 314, with 62.7% were females and 37.3% were males. The scores were calculated as percentages and statistically tested. Additionally, the impact of some socio-demographic factors (age, gender, education level, job, and salary) …
Ozonated Water Delays The Microbial Growth And Sensory Quality Loss Of Capia Pepper Fruit During Cold Storage, Yasi̇n Şi̇mşek, Mehmet Ali̇ Koyuncu, Derya Erbaş
Ozonated Water Delays The Microbial Growth And Sensory Quality Loss Of Capia Pepper Fruit During Cold Storage, Yasi̇n Şi̇mşek, Mehmet Ali̇ Koyuncu, Derya Erbaş
Turkish Journal of Agriculture and Forestry
The aim of the present research was to evaluate, for the first time, the effect of ozonated water treatments on the postharvest quality of capia pepper (Capsicum annuum L. ‘Kaptan’). The peppers were harvested at the optimum time and transported to the laboratory immediately. Uniform and quality fruit was selected and precooled. After precooling, the fruit was divided into four groups. The first three groups were immersed in ozonated water at three different concentrations (1.0, 2.0 and 3.0 ppm) for 15 min. The last group (control) was immersed in distilled water for 15 min. The peppers were kept at room …
An Untapped Resource: Exploring The Role Of Spirituality In The Psychological Healing Of African Asylum-Seekers From A Counselor’S Perspective, Brittany A. Duncan
An Untapped Resource: Exploring The Role Of Spirituality In The Psychological Healing Of African Asylum-Seekers From A Counselor’S Perspective, Brittany A. Duncan
Dissertations
This qualitative study explored how counselors perceive and integrate spirituality into the psychological healing of African asylum-seekers, a population facing compounded cultural, legal, and existential challenges. Using interpretative phenomenological analysis, the study examined the lived experiences of eight counselors working with this population. Findings revealed that counselors’ personal sense of religion influenced their comfort and approach in broaching spiritual topics, with both positive (e.g., spirituality as a source of support and community) and negative (e.g., religion as a source of suffering) associations shaping clinical engagement. Many participants reported limited access to trainings geared towards increasing their cultural competence related to …
Ameliorating Chromium-Induced Stress In Maize Through Phosphorus And Melatonin Application, Zunaira Zafar, Shoaib Ahmad, Muhammad Akhtar, Shafaqat Ali, Sarah Owdah Alomrani, Muhammad Ali Alshehri
Ameliorating Chromium-Induced Stress In Maize Through Phosphorus And Melatonin Application, Zunaira Zafar, Shoaib Ahmad, Muhammad Akhtar, Shafaqat Ali, Sarah Owdah Alomrani, Muhammad Ali Alshehri
Turkish Journal of Agriculture and Forestry
Chromium (Cr+6) toxicity is a significant environmental stress factor that severely hampers plant growth and productivity. This study aimed to evaluate whether the combined application of phosphorus fertilizer and melatonin could alleviate chromium induced stress in maize (Zea mays L.). A foliar spray of melatonin (50 µM) was applied alongside two phosphorus sources—phosphoric acid (PA) and diammonium phosphate (DAP), each at 60% of the recommended rate. Two maize cultivars (FH-1046 and YH-1898) were grown under chromium stress (0, 15, and 30 mg kg–1) to assess treatment effects. The results demonstrated that FH-1046 plants treated with PA + melatonin under noncontaminated …
A Pilot Study Of The Acute Effects Of Isometric Exercise And Aerobic Exercise For Improving Blood Pressure And Vascular Hemodynamics In Hypertensive Adults, Ayih Cedric Edoh
A Pilot Study Of The Acute Effects Of Isometric Exercise And Aerobic Exercise For Improving Blood Pressure And Vascular Hemodynamics In Hypertensive Adults, Ayih Cedric Edoh
ETDs from 2020-2029
Hypertension (HTN) is one of the most prevalent and modifiable risk factors for developing cardiovascular disease (CVD). Aerobic exercise is a well-known method to lower blood pressure (BP), but recently, isometric exercise has been purported to lower BP to a similar or greater extent. There is little known about the effects of isometric exercise on acute BP and 24-hour ambulatory blood pressure (ABP). Therefore, the purpose of this pilot study was to compare the effects of isometric and aerobic exercise on improving vascular hemodynamics and 24-hour ABP in hypertensive adults. METHODS: Seven participants (age 25-65 years) with a diagnosis of …
Epidemiology And Outcomes Of Geriatric Trauma At Uab, Lindy Reynolds
Epidemiology And Outcomes Of Geriatric Trauma At Uab, Lindy Reynolds
ETDs from 2020-2029
Adults over the age of 65 are the fastest growing portion of the population and account for a growing percentage of the trauma patient volume at trauma centers around the country. Older adults experience longer length of stays, higher mortality and complication rates than their younger counterparts. As a result, there has recently been an increased focus on models of geriatric trauma care, one of which is the addition of geriatric medicine consults for older trauma patients. The primary objectives of this dissertation were to examine the effect of the consult policy on outcomes using an interrupted time series approach, …
A Retrospective Analysis Of Dental Needs Identified By Intraoral Videography In Elderly Patients With Mild To Moderate Dementia In Long-Term Care Facilities: Feasibility Of A Novel Screening Mechanism For Oral Health, Kevin Hahn
ETDs from 2020-2029
This retrospective analysis explores the viability of employing intraoral videography to identify dental needs among long-term care (LTC) facility residents with cognitive impairment and/or mild to moderate dementia. Inadequate oral hygiene in these individuals can lead to dental plaque buildup, oral dysbiosis, gingivitis, dental caries, and periodontitis. Such conditions can impact both oral and systemic health. However, delivering oral hygiene in LTC facilities faces challenges due to care-resistant behavior triggered during mouth care. And many individuals in residential LTC facilities do not have access to dental care outside of severe emergencies due to cost, reimbursement patterns, lack of access to …
Statistical Methods For Mendelian Randomization Under Nonlinearity And Non-Normality, Mary Appah
Statistical Methods For Mendelian Randomization Under Nonlinearity And Non-Normality, Mary Appah
ETDs from 2020-2029
Instrumental variable (IV) methods are widely used for estimating causal effects in observational studies where unmeasured confounding may bias traditional regression estimates. The core idea is to use a variable referred to as an instrument that is associated with the exposure of interest, independent of unmeasured confounders, and influences the outcome only through the exposure. While originally developed in econometrics, IV methods have been increasingly adopted in epidemiology and genetic research under the framework of Mendelian Randomization (MR), where genetic variants, most commonly single nucleotide polymorphisms (SNPs), serve as instruments. MR provides a powerful tool for investigating causal relationships between …
Individual Responsibility And The Limits Of U.S. Dietary Guidelines: Addressing Ultra-Processed Food Consumption Through Structural Policy, Malika Al Kattan, Lynne Alexandra Kennedy
Individual Responsibility And The Limits Of U.S. Dietary Guidelines: Addressing Ultra-Processed Food Consumption Through Structural Policy, Malika Al Kattan, Lynne Alexandra Kennedy
All Works
No abstract provided.
The Change Of Yield, Growth, And Fruit Quality In Rubygem Strawberry Using Arbuscular Mycorrhizal Species, Selma Kuru Berk
The Change Of Yield, Growth, And Fruit Quality In Rubygem Strawberry Using Arbuscular Mycorrhizal Species, Selma Kuru Berk
Turkish Journal of Agriculture and Forestry
Arbuscular mycorrhizal fungi (AMF), which exist symbiotically with plant roots, affect plant growth, yield, and fruit quality. The effects of AMF vary depending on the cultivar and mycorrhizal type. In this study, the effects of different AMF types on the Rubygem strawberry cultivar, widely grown in Türkiye, were examined. Gigaspora margarita and Funneliformis mosseae AMF species were applied to plant roots at seedling planting. Fruit quality criteria, including yield, acidity, soluble solid content, phenolic compounds, organic acids, crown and root development, and the number of daughter plants and stolons, were examined. The highest yield was 431.02 g in G. margarita. …
Plant Extract-Enriched Mineral Beverages: Effects Of Temperature And Ultrasound Processing On Bioactive Content, Eli̇f Feyza Topdaş, İsa Arslan Karakütük, Memnune Şengül
Plant Extract-Enriched Mineral Beverages: Effects Of Temperature And Ultrasound Processing On Bioactive Content, Eli̇f Feyza Topdaş, İsa Arslan Karakütük, Memnune Şengül
Turkish Journal of Agriculture and Forestry
Functional beverages derived from herbal extracts have potential health benefits. There is a growing interest in these beverages because they are a sustainable and health-promoting alternative to conventional flavored drinks. This study aimed to produce phenolic rich mineralized herbal beverages using lyophilized purple basil, lavender, and thyme extracts at two different concentrations (2% and 4%). Changes in the physicochemical properties (pH, electrical conductivity, color, and viscosity), total phenolic content (TPC), total flavonoid content (TFC), total antioxidant capacity (2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2’-Azino-bis(3-ethylbenzothiazoline 6-sulfonic acid (ABTS) radical scavenging assays), and individual phenolic compounds were determined for beverages stored at 4, 25, and …
Multidimensional Scaling (Mds) Analysis Of Fire Blight Resistance In Apple Genotypes Selected From The Eastern Black Sea Region Of Türkiye, Kubi̇lay Kurtuluş Baştaş, Hati̇ce Dumanoğlu, Veli̇ Erdoğan, Ahmet Aygün, Rabi̇a Albayrak Deli̇ali̇oğlu, Sai̇d Efe Dost, Ümi̇t Serdar, Özgün Kalkişim, Sali̇h Maden, Zahi̇de Kocabaş
Multidimensional Scaling (Mds) Analysis Of Fire Blight Resistance In Apple Genotypes Selected From The Eastern Black Sea Region Of Türkiye, Kubi̇lay Kurtuluş Baştaş, Hati̇ce Dumanoğlu, Veli̇ Erdoğan, Ahmet Aygün, Rabi̇a Albayrak Deli̇ali̇oğlu, Sai̇d Efe Dost, Ümi̇t Serdar, Özgün Kalkişim, Sali̇h Maden, Zahi̇de Kocabaş
Turkish Journal of Agriculture and Forestry
Erwinia amylovora is the causal agent of fire blight, which is known as one of the most destructive diseases of apple. The use of fire blight-resistant cultivars/rootstocks is one of the most effective methods available to manage this disease. We previously selected 199 local apple cultivars that showed no clearly visible symptoms of fire blight on the plants from the coastline of the eastern Black Sea Region in Türkiye. The region is characterized by the highest rainfall and humidity levels in the country. In this research, young plants of these genotypes grafted onto MM.106 rootstock were screened for fire blight …
Effects Of Fenugreek And Shatavari On Vasomotor And Hormonal Balance In Ovariectomized Rats, Füsun Erten, Beşi̇r Er, Cemal Orhan, Abhijeet A. Morde, Muralidhara Padigaru, Kazi̇m Şahi̇n
Effects Of Fenugreek And Shatavari On Vasomotor And Hormonal Balance In Ovariectomized Rats, Füsun Erten, Beşi̇r Er, Cemal Orhan, Abhijeet A. Morde, Muralidhara Padigaru, Kazi̇m Şahi̇n
Turkish Journal of Agriculture and Forestry
Trigonella foenum-graecum L. (fenugreek, TFG) and Asparagus racemosus Willd. (shatavari, AR) have been extensively used in Ayurvedic, Unani, and traditional folk medicine to support women’s health. TFG seeds are traditionally employed as galactagogues and hormonal modulators, while AR roots are valued as rejuvenating tonics with phytoestrogenic activity, prescribed for menopausal complaints and reproductive well-being. Both plants also exhibit antioxidant and hepatoprotective effects, suggesting their potential as safe, nonhormonal alternatives to conventional hormone replacement therapy. This study investigated the dose-dependent effects of TFG and AR, administered individually or in combination, on vasomotor symptoms, hormonal balance, oxidative stress, and neuroendocrine markers in …
Derived Smoke Solution Mitigates Drought Stress In Forage Pea By Enhancing Antioxidant Defense Mechanisms, Medi̇ne Çopur Doğrusöz
Derived Smoke Solution Mitigates Drought Stress In Forage Pea By Enhancing Antioxidant Defense Mechanisms, Medi̇ne Çopur Doğrusöz
Turkish Journal of Agriculture and Forestry
This study was conducted to enhance plant resilience against drought stress, a major threat to agricultural production, by utilizing an eco-friendly application derived from agricultural waste. We investigated the protective effect of a smoke solution, derived from poppy harvest residues, on the biometric and biochemical parameters of two forage pea (Pisum sativum spp. arvense L.) varieties (GAP Pembesi and Özkaynak). Seeds were primed with 1% and 10% smoke solutions and grown under three distinct conditions: normal irrigation (control), moderate drought, and severe drought. Parameters including biometric traits, chlorophyll pigments, secondary metabolites, and antioxidant enzyme activities were analyzed. The smoke solution …
Bone Marrow Adiposity, Obesity, And Tumor Burden In Newly Diagnosed Multiple Myeloma, Ananya Deshpande
Bone Marrow Adiposity, Obesity, And Tumor Burden In Newly Diagnosed Multiple Myeloma, Ananya Deshpande
ETDs from 2020-2029
Multiple Myeloma (MM) is the second most common hematologic malignancy in the United States. It is characterized by the accumulation of clonally expanded plasma cells in the bone marrow, which leads to end organ damage and myeloma-defining events requiring treatment. The only modifiable risk factor for MM is obesity. However, associations between obesity, bone marrow adipocytes, and tumor burden at MM diagnosis remain unclear. We evaluated associations of bone marrow adipocytes, body mass index (BMI), and clinical features of tumor burden among 168 patients with histologically confirmed newly diagnosed multiple myeloma (NDMM) enrolled in the Integrative Molecular and Genetic Epidemiology …