Digital Commons Network^™

The Synapse-Net Macro-Architecture: An Integrated, Zero-Vent Framework For Decentralized Interstellar Transit, Christopher L. Eckes

Defensive Publications Series

Isolated deep-space exploration and long-duration terrestrial survival architectures are traditionally limited by systemic fragmentation, where propulsion, lifesupport, computational processing, and material reclamation operate as discrete, loss-heavy sub-units. This paper introduces the Synapse-Net Macro-Architecture, an un-gatekept, highly integrated engineering ecosystem that unifies exotic propulsion dynamics, solid-state nutritional synthesis, analog wave-based computing, and atomic hydrocarbon recycling into a single thermodynamic loop.

This paper establishes the structural interfaces, data routing protocols, and cross-system mass-energy linkages between four fundamental open-source baselines: the Tension-Line Fusion Tug, the Elemental Transmutation Replicator, the Cymatic Operating System, and the Hydrocarbon Reclamation Matrix. By formally mapping these cross-system dependencies, …

The Readiness Reset: Sleep, Stress, And Pain Management For Tactical Performance, Lauren Fried

Tactical & Occupational Performance Conference

Tactical professionals operate in high-demand environments where sleep disruption, chronic stress, and persistent pain are often normalized, but these factors significantly affect readiness, resilience, and long-term performance. This session explores how sleep, stress, and pain interact at the physiological and neurological levels to influence decision-making, recovery, injury risk, and operational effectiveness in first responders and military personnel.

Participants will gain a deeper understanding of how nervous system regulation, circadian rhythms, and pain perception affect both physical and cognitive performance under stress. Drawing on current research and applied human performance principles, this session highlights practical, field-applicable strategies that tactical professionals and …

Non-Football: The Hyperrationalized Nothingness Of Sporting Late Capitalism, David L. Andrews

Fast Capitalism

Over the past four decades, the origination and remarkable growth of the English Premier League (EPL, has transformed English football from what was a relatively parochial expression of a predominantly urban working class culture, into a mass entertainment-driven, multiple revenue-streamed, and globally consumed sport spectacle.  As such, this discussion engages and extends the voluminous critical scholarship on the EPL as an instructive object of cultural economic inquiry.  This is realized through a contextual model of the EPL as a hyper-rationalized non-football assemblage, largely based on a synthetic reading of Manuel DeLanda, Marc Augé, and George Ritzer’s conceptualizing.  This model forges …

Influence Of Smoking On Mlh1 Gene Polymorphism: Insights Into Colorectal Cancer Incidence, Ali Mohammed Al-Abedi, Rand Muhammed Abdul-Hussein Al-Husseini

Al-Bahir

Background: Colorectal cancer (CRC) is a leading cause of cancer-related mortality worldwide. The MutL Homolog 1 (MLH1) gene plays a critical role in DNA mismatch repair (MMR). Evidence suggests cigarette smoking increases CRC risk, potentially interacting with genetic factors.

Materials and Methods: This case-control study involved 50 Iraqi CRC patients and 50 age- and gender-matched healthy controls. The PCR-RFLP technique was employed for genotyping the -93G/A (rs1800734) polymorphism. Statistical analysis included Chi-square, Fisher's Exact Test, and logistic regression adjusted for confounders. Hardy-Weinberg Equilibrium (HWE) was assessed in controls.

Results: The frequency of the rs1800734 variant was significantly higher in CRC …

The Elemental Transmutation Replicator: A Decentralized Blueprint For Closed-Loop Biometric Molecular Synthesis, Christopher L. Eckes

Defensive Publications Series

This white paper introduces a decentralized, zero-agriculture appliance architecture designed to synthesize tailored human nutrition directly from elemental feeds, ambient water vapor, and atmospheric carbon dioxide (CO₂). The Elemental Transmutation Replicator (ETR) bypasses traditional biological growth cycles by utilizing an ultra-vacuum Atomic Layer Deposition (ALD) chamber coupled with a Piezoelectric Acoustic Layering Matrix (PALM) to assemble pure amino acids, medium-chain triglycerides, and essential micro-nutrients atom-by-atom. System inputs are dynamically calibrated in real time via an integrated multi-spectral optical and dermal biometric scanning array. This paper details the structural architecture, the 5-stage synthesis loop, and the thermodynamic solutions required to overcome …

A Rho5-Cnc1-Dnm1 Signalling Module Coordinates Multi-Organelle Execution Of Regulated Cell Death In Yeast, Justin Bauer

Theses and Dissertations

Regulated cell death is a conserved process with major implications for health and disease, yet how yeast cells integrate stress signals to determine survival versus death remains unclear. This thesis investigates Cyclin C (Cnc1), a conserved Mediator kinase module component with both transcriptional and mitochondrial roles. Together with Cdk8 Cnc1 primarily represses stress response genes, while upon stress it translocates to the mitochondria to induce mitochondrial fragmentation with the dynamin-related GTPase Dnm1. Using structure-guided separation-of-function mutants, I demonstrate that Cnc1-dependent death requires its mitochondrial function rather than its transcriptional role, and that its effector Dnm1 acts as a signaling node …

Comprehensive Geriatric Assessment Identifies Multidimensional Vulnerabilities In Older Adults With Heart Failure, Ci̇han Kiliç, Rengi̇n Demi̇r, Özlem Yilmaz Aykent, Zerri̇n Yi̇ği̇t, Pinar Küçükdağli, Banu Özulu Türkmen, Güli̇stan Bahat, Mehmet Aki̇f Karan

Turkish Journal of Medical Sciences

Background/aim: Heart failure (HF) in older adults is frequently accompanied by geriatric syndromes that remain unrecognized in conventional cardiac evaluations. The vulnerabilities of older adults with and without HF in terms of muscle strength, physical performance, functional capacity, frailty, nutritional status, cognition, mood, anxiety, polypharmacy, and comorbidity were investigated using comprehensive geriatric assessment (CGA).

Materials and methods: A cross-sectional study was conducted in two academic outpatient clinics, enrolling 420 adults aged ≥60 years, including 92 (21.9%) with HF. Data included sociodemographic characteristics, anthropometric measurements, and CGA parameters: handgrip strength, the Five-Times Sit-to-Stand Test (FTSST), the Short Physical Performance Battery (SPPB), …

Urinary Dkk3 As A Predictor Of Ckd Stages In Reflux Nephropathy In Children, Ayşe Seda Pinarbaşi, Nesli̇han Günay, İnayet Güntürk, Di̇dem Barlak Keti̇, Si̇bel Yel, Sekure Rabi̇a Ulueren, Cevat Yazici, Muammer Hakan Poyrazoğlu, İsmai̇l Dursun

Turkish Journal of Medical Sciences

Background/aim: Reflux nephropathy is an important cause of chronic kidney disease (CKD) in children. The search for new biomarkers continues, as early intervention is important to slow the progression of CKD. Urinary Dickkopf-3 (uDKK3), a potential marker of tubulointerstitial fibrosis, has been studied in adults but not extensively in children with CKD. This study was conducted to determine the role of uDKK3 levels in predicting the CKD stage in children with reflux nephropathy.

Materials and methods: This cross-sectional study included 113 children with CKD stages 1–4 with reflux nephropathy and 28 healthy controls. uDKK3 concentrations were measured using enzyme-linked immunosorbent …

Association Of Vitamin D, Oxidative Stress Markers, And Hormonal Factors With Male Infertility: A Case-Control Study In Pakistan, Muhammad Tayyab Ihsan, Ayesha Ali Malick, Sher Khan, Sher Khan, Muhammad Tahir Khan, Haq Nawaz Khan, Rehana Rehman

Turkish Journal of Medical Sciences

Background/aim: Infertility impacts around 15% of couples worldwide, with male factors accounting for approximately 50% of cases. Despite this significant share, male infertility remains understudied, particularly in developing nations such as Pakistan. The present study explores the association between male infertility and seminal plasma concentrations of oxidative stress markers, inhibin B, and vitamin D, along with their relationship with sperm parameters.

Materials and methods: The dataset of the study consisted of seminal plasma levels from 30 fertile and 60 infertile males. Total antioxidant capacity (TAC), Vitamin D, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), lipid peroxide (LPO), superoxide dismutase (SOD), and inhibin B …

Omega-3–Rich Fish Oil Lipid Emulsions Significantly Prevent Sepsis-Driven Mesenteric Hypoperfusion And Multi-Organ Injury In Murine Models, Gökşen Öz, Esi̇n Özçelebi̇, Ayşe Yeşi̇m Göçmen, Cenk Sükmensüer, Selma Yildirim, Arzu Topeli̇, Alper Bektaş İski̇t

Turkish Journal of Medical Sciences

Background/aim: Parenteral feeding is used in critically ill patients when enteral nutrition is inadequate or intolerable, and the gastrointestinal tract is not functioning properly. Lipid emulsions play a major role in parenteral nutrition because they supply necessary fatty acids and a high-calorie density. We investigated the effects of parenteral lipid emulsions on mesenteric perfusion, inflammation-induced oxidation, and organ damage in lipopolysaccharide-induced mice endotoxemia model.

Materials and methods: In septic mice, organ damage induced by lipopolysaccharide was assessed by histopathology and biochemical examination. Additionally, an ultrasonic blood flowmeter was used to measure the impact of lipid emulsions on mesenteric blood flow. …

Bridging The Gap Towards Sustainable Development: A Systematic Literature Review On Orang Asli Communities In Peninsular Malaysia, Nurfatiha Akmal Fawwazah Abdullah-Fauzi, Nursyuhada Othman, Hidayah Haris, Nur Hartini Sariyati, Farah Farhana Ramli, Kaviarasu Munian, Mohd Faudzir Najmuddin, Mohd Tajuddin Abdullah, Muhammad Abu Bakar Abdul-Latiff

Forest and Society

Orang Asli communities in Peninsular Malaysia have a complex history marked by challenges related to land rights, environmental degradation, and cultural preservation. Despite ongoing efforts to address these challenges, significant obstacles persist, particularly in healthcare access and outcomes, education, language preservation, dietary practices, religious beliefs, and policy frameworks. This systematic literature review aims to provide a comprehensive analysis of past and current research on various aspects of Orang Asli communities in Peninsular Malaysia. The primary goal is to uncover the trends of challenges and unique characteristics of the Orang Asli communities while offering valuable recommendations for improvement. The Preferred Reporting …

An International Multidisciplinary Consensus Statement On Laparoscopic Liver Biopsy, Si Yi Lei, Yu Han, Don C. Rockey, Khalid Alswat, Vincent Wai Sun Wong, Nozim Jumaev, Carlos Jesus Toro-Huamanchumo, Safwan Taha, Mohamed El-Kassas, Jacob George, Mark Muthiah, Omar Ghanem, Masato Yoneda, Dao Viet Hang, Giada Sebastiani, George Papatheodoridis, Adam Abu-Abeid, Andrew G. Robertson, Sang Hyun Kim, Rudolf Weiner, Kamal Mahawar, Asim Shabbir, Mohammad Kermansaravi, Reynu Rajan, Yosuke Seki, Halit Eren Taskin, Scott Shikora, Edward Oliveros, Chetan Parmar, Qiuye Cheng, Omar Thaher, Elena Ruiz-Úcar, Rodolfo Oviedo, Rui Ribeiro, Mario Musella, Almino C. Ramos, Seung-Wan Ryu, Tamer Abdelbaki, Wei Jei Lee, Man Pan Chan, Jose Eduardo Garcia Flores, James Skinovsky, Ahmad Madkhali, Sylvia Weiner, Frank Tacke, Wah Yang, James Neuberger, Ming-Hua Zheng

Research outputs 2022 to 2026

Laparoscopic liver biopsy (LLB) provides a way to obtain liver tissue samples under direct visual inspection of the liver surface. It complements percutaneous liver biopsy (PLB) for complex or high-risk cases where PLB cannot be performed. Clinical practices for LLB vary across centers due to the lack of international standards. To improve the procedural quality and diagnostic efficiency of LLB, a multidisciplinary panel of 45 international experts from 6 continents, including hepatology, hepatobiliary surgery, gastrointestinal surgery, and metabolic and bariatric surgery, developed this consensus statement through three rounds of a modified Delphi process. This consensus covers clinical application scenarios, high-risk …

Pa Dent J March 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Jan 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Jul 2022

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

Pa Dent J Sept 2024

Pennsylvania Dental Journal

The Pennsylvania Dental Journal is produced by the Pennsylvania Dental Association six times a year, in January, March, May, July, September and November. Issues include regular columns with regional news impacting the Pennsylvania membership including editorial and government relations news, association activities, member updates, continuing education opportunities, and classifieds.

An Assessment Of Career Development Affecting Factors In The Construction Industry From A Gender Perspective, Thuy Thi Nguyen, Toan Quoc Nguyen, Binh Thuy Pham

CIB Conferences

The Vietnamese construction industry has experienced rapid growth in recent years, with an average annual growth rate exceeding 8.0%. At this pace, the construction workforce is projected to reach approximately 12–13 million workers by 2030, of whom women are expected to account for around 10%. Despite their increasing participation, women are widely perceived to face greater challenges in career development than men within the construction sector. This paper aims to be an assessment of career development drivers in the construction industry from a gender perspective. A questionnaire survey was administered to 120 engineers to evaluate the influence of ten factors …

The Impact Of Commute Length On Safety And Wellbeing In Uk Construction Workers, Amy Brandreth, Billy Hare, Kenneth Lawani

CIB Conferences

This paper, contributing a small part to a related PhD, uses a systematic literature review approach to examine the impact of commuting on fatigue, safety and wellbeing among construction workers. Eight empirical studies were analysed using Braun and Clarke’s thematic analysis with three themes being identified: commute length, long working hours and commuting vs staying away from home. The results indicate that commutes can far exceed the UK average commute length, and this, combined with long working hours, reduces sleep opportunities. However, staying away from home introduces lifestyle and environmental factors, such as diet and exercise, which may also impair …

Nutrition And Wellbeing In Construction: Exploring Dietary Practices For Safer Healthier Workforces, Emmanuel Aboagye-Nimo, Charlie Roberts, Lewis Gough

CIB Conferences

Construction workplaces significant physical and cognitive demands on workers, yet the role of nutrition in supporting energy, concentration and safety is seldom addressed in industry discourse. This study explores how construction workers understand and manage their daily eating habits, and how these habits influence performance, wellbeing and risk. The research forms part of an ongoing qualitative inquiry, using semi‑structured interviews with workers from a range of roles including bricklayers, plasterers, waste management teams and site managers. Early findings indicate considerable variation in nutritional practices, shaped by time pressures, cost, convenience and site routines. While some workers rely heavily on fast …

Optimizing The Use Of Grazed Dryland Pasture In Western Oregon, T E. Bedell

IGC Proceedings (1977-2023)

When they are properly fertilized, western Oregon dryland pastures of subterranean dover with grasses such as perennial rp:g:rass, tall fescue, and resident annuals produce total annual dry-matter yields averaging 6,500 kg/ha. Some sites are capable of over 9,000 kg/ha. Optimum use of this forage is complicated by its highly seasonal availability. Over 50 % of the total growth occurs from late April to mid-June. Only about 10% takes place during autumn-early winter, and virtually none occurs during summer. Research shows livestock weight gains from 300 to over 700 kg/ha can be expected depending upon pasture mixture and kind of grazing …

Diet Quality Considerations In The Design And Management Of Pastures In Seasonally Dry Tropics Of Australia, R L. Mccown, C J. Gardener

IGC Proceedings (1977-2023)

Much of Australian tropical-pasture research in the last 20 years has been aimed at filling the "protein gap" of the dry season with a well-adapted legume. Several such legumes are now available, but their contribution to an improved nutritional regimen has been variable. This paper puts forward generalizations as to the contribution of pasture components to cattle nutrition and attempts to apply this information in devising regional strategies for pasture design and management. The contribution of a forage component is a function of (1) its nutritive value and (2) its relative acceptability. Three components emerge as both highly nutritious and …

Development Of A Pasture Research Program For The Tropical Savanna Region Of Brazil, D Thomas, C P. Moore, W Couto, R P. De Andrade, C.M C. Da Rocha, D T. Gomes

IGC Proceedings (1977-2023)

The tropical savannas (cerrados) of west central Brazil contain almost 40% of the nation's cattle population. However, the low productivity and nutritive value of the native pastures is a serious limitation to cattle production. To improve the nutrition of the grazing animal, a research program has been developed with emphasis on the integrated use of cultivated pastures. The program aims (1) to select species adapted to the cerrados, (2) to determine their nutrient requirements, and (3) to develop methods of establishment and utilization. The program is being conducted at the Cerrados Agricultural Research Center (CP AC) at lat 15°S. Rainfall …

Yield And Quality Of Tropical Legumes During The Dry Season: Galactia Striata (Jacq.) Urb., R R. Vera, E A. Pizarro, M Martins, J.A. C. Viana

IGC Proceedings (1977-2023)

A small-plot experiment was conducted during 2 consecutive years in the cerrados of Brazil to evaluate the effect of four dates of deferment (21 February, 7 and 21 March, and 4 April, respectively) on rate of growth, chemical composition, and in-vitro dry-matter digestibility (IVDMD) of a pure stand of Galactia striata, a naturalized legume. The chosen dates of deferment em­braced the last 2 months of the rainy season. Yields were estimated at intervals of 28 days, over an experimental period of 237 days, ending with the beginning of the following rainy season. Asymptotic growth was observed throughout the experimental period. …

Simulation Using Aspiration Screening Tool And Bolus Testing For Graduate Nutrition And Dietetics Students, Kendrea Garand, Tracy Maluchnik, Trisha A. Cousins, Jonathan Beall, James Coyle

Teaching and Learning in Communication Sciences & Disorders

Utilization of simulation is increasing during pre-professional training of allied health disciplines, including speech-language pathology and nutrition/dietetics programs. The impact on student learning using simulation in the areas of dysphagia assessment and management has begun to emerge. The purpose of this study was to explore learning outcomes of 21 students enrolled in a Nutrition and Dietetics graduate program prior to and after didactic and hands-on application learning experiences, including employment of an aspiration screening tool and modification of food/liquid textures. The didactic and practical portions were led by speech-language pathology faculty. A pre- and post-test was analyzed to determine change …

The Effect Of Weight Training With Blood Flow Restriction On Muscle Strength Development In Mma, Tomáš Kozák, Marek Kokinda, Pavel Ružbarský

Baltic Journal of Health and Physical Activity

Background: This study aimed to elucidate the effect of weight training with blood flow restriction (BFR) on explosive power and isokinetic strength in combat athletes. Materials and methods: The sample included 12 male MMA fighters divided into a control (19.50±0.50 years) and an experimental (18.00±1.00 years) group. Participants trained twice weekly for 8 weeks, with BFR in the experimental group. Explosive power was assessed using following tests by Optogait: countermovement push-up, kneeling countermovement push-up and kneeling squat push-up for upper limbs and countermovement jump, countermovement jump with free arms and squat jump for lower limbs. Isokinetic strength was measured by …

An Intelligent Packaging Materials Management And Optimisation For The Production Process, A. Abdulkareem, C. O. Ijagbemi, B. Kareem

The Journal of Engineering Research

An intelligent model was formulated to aid in the packaging materials management and optimisation for the production process. This was done after generating a 2D drawing using AutoCAD software for each of the popular packaging material shapes utilised in the production system. In modelling, uniform (regular) and non-uniform (irregular) packaging containers were considered in the determination of forces, areas, volumes, weights, densities, among other relevant parameters. Three packaging materials: ceramic glass, plastic and laminated cardboard containing processed water and other beverages in 75 cl, 50 cl, 33 cl and 1 litre respectively were considered during model testing. Results showed that …

Queer, Hybrid Participatory Design: Relational Practices And Norms For Coalition Building With Rural, Lgbtq+ Communities, Luettamae Lawrence, Maureen Boyle, Chasity Mayo, Catherine A. Rushworth, Moira Anderson, Dorothy Wallis, Jayme Walters

Instructional Technology and Learning Sciences Faculty Publications

This paper examines the first year of collaboration between the Bear River Region LGBTQ+ Community Coalition and queer residents in rural northern Utah, United States, using a hybrid participatory design (PD) approach. Using Yep’s queer relationality theory, we examine how hybrid spaces were designed and iteratively adapted to support inclusion, care, and collective agency among LGBTQ+ community members. Drawing on Community Coalition Action Theory and queer PD, we analyze four cases from May 2024 to June 2025 including workshops and regular meetings to explore how relational practices evolved across different formats and phases of coalition development. In this paper, we …

Intrusive Advising Practices And Community College Credential Attainment In Rural Students, Leslie Reeder

College of Education

This qualitative narrative study addressed the persistent problem of lower postsecondary completion rates among rural students, particularly first-generation students, whose lower educational attainment contributes to economic challenges and diminished quality of life in rural communities. Guided by Bronfenbrenner’s ecological systems theory, this study examined first-generation rural students’ perceptions of their experiences with secondary and postsecondary advisors and the impact of intrusive advising on postsecondary credential attainment. The study explored how students described advising experiences and how intrusive advising influenced persistence and credential completion. Data were collected through semi-structured interviews with first-generation rural students and analyzed using thematic analysis. Five themes …

Vitamin D Deficiency And Adverse Cardiovascular, Metabolic, And Mortality Outcomes In Adults With Obstructive Sleep Apnea: A Propensity-Matched Retrospective Cohort Study, Andrew Cecil, Ekow Essien, Abena Agyekum, Gloria Amoako

Aurora GME

OBJECTIVE: Vitamin D deficiency is highly prevalent in obstructive sleep apnea (OSA) and implicated in metabolic dysregulation and cardiovascular disease. This study examined associations between vitamin D deficiency and adverse cardiovascular, metabolic, and mortality outcomes in adults with OSA.

METHODS: This retrospective cohort study utilized the TriNetX Global Collaborative Network spanning 155 healthcare organizations. Adults (≥18 years) with OSA (ICD-10: G47.33) were stratified by serum 25-hydroxyvitamin D3 into deficient (≤12 ng/mL, n=64,205) and sufficient (≥20 ng/mL, n=64,205) cohorts following 1:1 propensity matching. Primary outcomes included all-cause mortality, myocardial infarction, heart failure, pulmonary embolism, chronic kidney disease, hypertension, type 2 diabetes, …

Community - Volume 11

be Still

No abstract provided.