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Articles 2371 - 2400 of 14246
Full-Text Articles in Entire DC Network
Empirical Antibiotic Use In Children With Acute Fever: Clinical Evidence And Sociocultural Perspectives Literature Review, Hussein Moustafa Shehata, Ranya Khairy Ammar
Empirical Antibiotic Use In Children With Acute Fever: Clinical Evidence And Sociocultural Perspectives Literature Review, Hussein Moustafa Shehata, Ranya Khairy Ammar
Journal of Pediatric Infectious Diseases
Objective: Empirical antibiotic therapy in children with acute fever remains a controversial clinical issue. Fever is one of the most common presenting symptoms in pediatric care, yet most febrile episodes are self-limiting and attributable to viral infections. To evaluate the clinical evidence on empirical antibiotic therapy in febrile children, assess clinical outcomes, synthesize international guideline recommendations, and analyze the impact of sociocultural factors on prescribing practices. Methods: A narrative literature review was conducted using PubMed/MEDLINE, Embase, and Google Scholar (January 2014 – March 2025), supplemented by guideline databases from the World Health Organization (WHO), the European Society for Paediatric Infectious …
Shadows Of Salem: Recovered Memories In The Sandusky Case, Stewart Justman
Shadows Of Salem: Recovered Memories In The Sandusky Case, Stewart Justman
Global Humanities and Religions Faculty Publications
In 2012 the former Penn State football coach Jerry Sandusky was convicted of 45 counts of the sexual abuse of children. However, none of his accusers accused him of anything until Victim 1, Aaron Fisher, entered treatment with a psychologist who diagnosed him at first sight as a victim of sexual abuse. The psychologist denied that he engaged in recovered-memory therapy. The record suggests otherwise. If a competent defense had shown at trial that the psychologist practiced on Victim 1 the same mode of therapy he rejected out of hand, the case against Sandusky might have collapsed, much as the …
Cultivating Narratives: A Critical Discourse Analysis Of Higher Education Student-Led Farms And Gardens, Maximilan Sherard, Marc T. Sager
Cultivating Narratives: A Critical Discourse Analysis Of Higher Education Student-Led Farms And Gardens, Maximilan Sherard, Marc T. Sager
Publications
Despite extensive research on community agriculture, little attention has been paid to student-led farms or gardens (SFGs) in higher education contexts. SFGs represent a unique site for community agriculture due to their diverse stakeholders, academic affiliations, and the institutional policies they navigate. This study examines online promotional materials from 42 SFGs located on land-grant higher education campuses across the United States. Using critical discourse analysis, we (1) map these organizations’ practices and (2) identify competing discourses about community and agriculture within their promotional narratives. We identify and explain four core practices (membership, growing, distribution, and purpose) and connect these practices …
Fair + Equitable July 2026, International Association Of Assessing Officers
Fair + Equitable July 2026, International Association Of Assessing Officers
Fair + Equitable
The July F+E issue reviews how eliminating the property tax would impact local budgets.
Also in this issue:
- An updated Annual Conference session schedule
- The President’s Column
- IAAO launches national campaign to explain the value of the property tax
- Longtime IAAO director retires
- The 2026 conference charity
- IAAO Library hot topics
- New IAAO designees
- Meet A Rep
Field Trials Report 2025: Wa Farming Systems Project (Daw2204-003rtx), Department Of Primary Industries And Regional Development, Western Australia
Field Trials Report 2025: Wa Farming Systems Project (Daw2204-003rtx), Department Of Primary Industries And Regional Development, Western Australia
Farm Systems and Economics research reports
In 2025 the Western Australian Farming Systems Project continued its program of field trials, from Northampton in the north to Wittenoom Hills in the south, to address our project outputs; investigate diversity within farming systems, evaluate changes in sowing opportunities, identify profitable low greenhouse gas emission options and monitor crown rot following diverse crop sequences.
A Comparative Study Of Aging And Cortical Folding In Chimpanzees And Olive Baboons, William D. Hopkins, Angela M. Achorn, Michele M. Mulholland, Elizabeth R. Magden, Steven J. Schapiro, Courtney L, Fults, Jean‐Francois Mangin, Adrien Meguerditchian
A Comparative Study Of Aging And Cortical Folding In Chimpanzees And Olive Baboons, William D. Hopkins, Angela M. Achorn, Michele M. Mulholland, Elizabeth R. Magden, Steven J. Schapiro, Courtney L, Fults, Jean‐Francois Mangin, Adrien Meguerditchian
Anthropology Faculty Publications
In light of the evidence that nonhuman primates naturally develop Alzheimer's disease neuropathologies, there is a renewed interest in research on the comparative biology of aging, including neurological changes across the age groups in species with diverse lifespans. In this paper, we examined age‐related differences in two measures of cortical folding, mean depth and fold opening, in a sample of chimpanzees (Pan troglodytes) and olive baboons (Papio anubis). We found significant species differences in the slope and pattern of age‐related changes in cortical folding. As predicted, chimpanzees showed negative linear associations between age and mean depth and …
Cryptic Habits: The Hidden Lives Of Midsouth Entomologists. Interview With Dr. Jerome Goddard, Mississippi Public Health Entomologist And Fiction Novelist, C. J. Peterson, Jerome Goddard
Cryptic Habits: The Hidden Lives Of Midsouth Entomologists. Interview With Dr. Jerome Goddard, Mississippi Public Health Entomologist And Fiction Novelist, C. J. Peterson, Jerome Goddard
Midsouth Entomologist
No abstract provided.
Trial By Fire: Disaster Justice And Lessons Learned, Clifford Villa
Trial By Fire: Disaster Justice And Lessons Learned, Clifford Villa
Faculty Scholarship
Disaster Justice reflects the intersection of environmental justice and disaster law. The study of disaster justice is becoming increasingly essential as disasters become more frequent and devastating in the face of accelerating climate change. Disaster law is marked by statutes such as the federal Stafford Act and by theory such as the “disaster cycle” of readiness, response, and recovery. Environmental justice recognizes that the distribution of harms such as bad air or water quality may be distributed inequitably among groups such as low-income populations or racial minorities. In similar fashion, the adverse impacts of disasters may also be distributed inequitably …
Towards Clinical Translation Of Nanomedicines: Formulation Scale-Up And Model Systems., Owen M Kelly, Andrew R Hanna, Addison K Byrne, Jonathan A Green, Iuri Viotti Perisse, Kevin D Wells, Stephen A. Murray, Jie Xu, Y Eugene Chen, Irina A Polejaeva, Alice F Tarantal, David Issadore, Alexandra S Piotrowski-Daspit
Towards Clinical Translation Of Nanomedicines: Formulation Scale-Up And Model Systems., Owen M Kelly, Andrew R Hanna, Addison K Byrne, Jonathan A Green, Iuri Viotti Perisse, Kevin D Wells, Stephen A. Murray, Jie Xu, Y Eugene Chen, Irina A Polejaeva, Alice F Tarantal, David Issadore, Alexandra S Piotrowski-Daspit
Faculty Research 2026
Non-viral nanomedicines, including nanoparticles (NPs) composed of lipids and polymers, represent a transformative approach to drug and gene therapy. However, clinical translation of these technologies is limited by two key barriers: the scale-up of NP formulations and the challenge of conducting predictive preclinical studies in relevant animal models. Efficient upscaling of nanomedicines, from cost and material requirement perspectives, requires manufacturing processes that can reliably provide products across the many orders of magnitude of scale from discovery (kg of product). Additionally, initial preclinical studies are often performed in mouse models for discovery; however, mid- to large-size animal models such as rabbits, …
Butte Reclamation Evaluation System Corrective Action Plans For Reclaimed Sites 2025 Bres Site Specific Corrective Action Plans For Quadrant 2, Butte-Silver Bow Department Of Reclamation And Environmental Services
Butte Reclamation Evaluation System Corrective Action Plans For Reclaimed Sites 2025 Bres Site Specific Corrective Action Plans For Quadrant 2, Butte-Silver Bow Department Of Reclamation And Environmental Services
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.
Agricultural Extension Agents’ Perceptions Regarding The Use Of Social Media In Extension Work, Howard M. Wallace Ii, K. S. U. Jayaratne, Wendy Warner, Dara Bloom, Julia Mckeown
Agricultural Extension Agents’ Perceptions Regarding The Use Of Social Media In Extension Work, Howard M. Wallace Ii, K. S. U. Jayaratne, Wendy Warner, Dara Bloom, Julia Mckeown
Journal of Human Sciences and Extension
Social media enables Extension agents to reach a large group of clients efficiently. However, research on agricultural Extension agents’ perceptions about social media use in Extension work is limited. The purpose of this study was to determine the perceptions of agricultural Extension agents regarding the use of social media in Extension work. This was a descriptive research study conducted online. Findings confirmed that agricultural Extension agents in North Carolina State find social media helpful in Extension work, such as for the distribution of information to their clients and extending its reach to a larger audience. Extension agents perceive that using …
A Comparison Of Regional Food Systems And Food Security In Rural Mississippi And Italy, Reinhard M. Knerr, Athan M. Gregory, Anne Cafer
A Comparison Of Regional Food Systems And Food Security In Rural Mississippi And Italy, Reinhard M. Knerr, Athan M. Gregory, Anne Cafer
Journal of Human Sciences and Extension
In the Mississippi (MS) Delta, more than 40% of residents are food-insecure despite predominantly agricultural land use. We hypothesized that limited social networks and non-navigable food market systems constrain MS producers, limit market viability, and hinder regional food sovereignty. This ethnography compared rural Italian and Mississippian food systems through semi-structured interviews of food producers, processors, and marketers. We described differences in social networks between groups that led to differential capacities to share capital and to overcome producer and labor constraints. We also described key differences in governmental and Extension support of local food systems. Finally, we provided suggestions for addressing …
In Vivo Chemiluminescent Probes For Near-Infrared, Copper, And Nitric Oxide Imaging, Rokia Osman
In Vivo Chemiluminescent Probes For Near-Infrared, Copper, And Nitric Oxide Imaging, Rokia Osman
Chemistry Theses and Dissertations
Optical in vivo imaging is a key way to understand complicated intracellular mechanisms and supporting the development of disease therapies by elucidating the main causes of the pathology. Chemiluminescence is an emerging imaging modality that offers increased sensitivity and deep in vivo imaging.
The work in this thesis is based on modulation to phenoxy dioxetane structures to further in vivo imaging. First, we developed a turn-on chemiluminescent copper probe which was designed by linking a picolinic acid moiety to the phenolic substituent of a spiroadamantane 1,2-dioxetane. The sensitive limit of detection of 360 nM allows for tracking copper reactivity in …
Exploring Immune Priming In The Species Exaiptasia Diaphana, Torrence Campos
Exploring Immune Priming In The Species Exaiptasia Diaphana, Torrence Campos
Biology Theses
Vibrio coralliilyticus is a pathogen that infects various coral species across several reef ecosystems and causes mortality within a span of a few days. With increasing temperatures, the pathogen becomes more virulent towards coral. Probiotics such as MCH1-7 have previously been used to treat infected corals before and after exposure to V. coralliilyticus. In this study, we will be using a species of sea anemone Exaiptasia diaphana in place of coral to evaluate the effects of two V. coralliilyticus strains ATCC BAA-450 and OFT6-21. It was determined that BAA-450 was more virulent. It led to immediate stress and higher mortality. …
Made In America, Hidden By Ai: Ai Shopping Chatbots Reveal How Amazon And Walmart Hurt American Manufacturers And Deceive Shoppers, Erie Meyer, Zachary Harris
Made In America, Hidden By Ai: Ai Shopping Chatbots Reveal How Amazon And Walmart Hurt American Manufacturers And Deceive Shoppers, Erie Meyer, Zachary Harris
Center for Law and the Economy
This article investigates the capabilities of two AI shopping agents — Alexa for Shopping and Sparky, operated by Amazon and Walmart respectively — to identify country of origin for products on their respective platforms and flag potential “Made in USA” misrepresentations — where products with “Made in USA” in their title or listing have another country or “imported” listed as their country of origin. This article finds that (1) Amazon and Walmart have the technical capability to detect and flag “Made in USA” fraud; (2) “Made in USA” fraud appears to be common on both Amazon and Walmart; (3) Amazon …
Shopping Mall Revitalization As Experiential Transformation: A Mixed-Method Case Study Of Mall Atmosphere And Visitor Experience, Adeanna P. Pertiwi, Antony Sihombing
Shopping Mall Revitalization As Experiential Transformation: A Mixed-Method Case Study Of Mall Atmosphere And Visitor Experience, Adeanna P. Pertiwi, Antony Sihombing
CSID Journal of Infrastructure Development
Shopping malls are under growing pressure to stay relevant as e-commerce reshapes consumer behaviour and reduces foot traffic in physical retail environments. Although revitalization has become a common response, most studies evaluate it through physical outcomes alone, and the question of how spatial and atmospheric changes translate into shifts in visitor experience remains largely unaddressed. This study examined shopping mall revitalization as an experiential transformation, with the aim of understanding how physical and atmospheric changes shaped visitor experience at Lippo Mall Nusantara, South Jakarta. A mixed-method approach was used. The approach combined direct observation and photographic documentation with a questionnaire …
Nebraska And The Midwest Agtech Ecosystem: Benchmarking Innovation Investment And Translation Gaps, Ankit Chandra, Ishani Lal, Brennan Costello
Nebraska And The Midwest Agtech Ecosystem: Benchmarking Innovation Investment And Translation Gaps, Ankit Chandra, Ishani Lal, Brennan Costello
Department of Agricultural and Biological Systems Engineering: Presentations and White Papers
Agricultural innovation is central to the sustainable transformation of food systems, yet the capital that finances it is unevenly distributed relative to where food is produced. This paper develops a diagnostic framework for measuring this mismatch and applies it across the U.S. Midwest from 2021 to 2025, with particular emphasis on Nebraska's structural position within this landscape. Drawing on venture capital deal-flow data, 17 stakeholder interviews, and a novel strength-weakness-opportunity-gap (SWOG) ecosystem mapping methodology, we document $736 million in tracked Midwest AgTech funding across eight states (Nebraska, Iowa, Missouri, Illinois, Indiana, Kansas, North Dakota, and South Dakota). We introduce three …
Reconciling Faith And Academic Identity: Evangelical Christian Identity And Ontological Confusion In Sport Studies, Sean Burke
Movement and Being: The Journal of the Christian Society for Kinesiology, Leisure and Sports Studies
This paper investigates the interplay of ontological confusion and Evangelical Christian identity within the context of qualitative sport studies research. Employing a reflexive autoethnographic method, I explore my personal experiences as an Evangelical Christian and as a social scientist who grapples with the complexities of paradigmatic confusion. Personal vignettes highlight the influence of sporting spaces and figures such as Tim Tebow and Kurt Warner in shaping my faith, identity, and framework for understanding reality. The analysis delves into the challenges posed by competing paradigmatic orientations, including positivism and social constructivism. These paradigms reveal the inherent difficulty of aligning scholarly inquiry …
Salary Report, 2026 July, Eastern Michigan University
Salary Report, 2026 July, Eastern Michigan University
EMU Salary Reports
No abstract provided.
Man, Cut The Crop: Effects Of Cropectomies On Survival And Behavior In Drosophila Melanogaster, Emily Peraza
Man, Cut The Crop: Effects Of Cropectomies On Survival And Behavior In Drosophila Melanogaster, Emily Peraza
Florida Atlantic Undergraduate Research Journal
The gut-brain axis mediates communication between the digestive and nervous systems to regulate physiology and behavior. Its dysfunction profoundly impacts human health and causes disease. Region-specific hormones and neurotransmitters in the digestive system respond to several processes to signal the brain, but the mechanisms of gut-brain signaling are not fully defined. Drosophila melanogaster is a powerful model for studying gut biology by showing remarkable similarity to mammalian digestive systems, as both regulate energy by distributing nutrients. We refined a minimally invasive surgical protocol to remove the crop from adult flies. We then utilized the Activity Recording CAFE (ARC) and Drosophila …
Essays In Applied Microeconomics, Md Tahmeed Hossain
Essays In Applied Microeconomics, Md Tahmeed Hossain
Economics Theses and Dissertations
This dissertation contributes to empirical economics research by examining three settings in which historical shocks, behavioral constraints, and localized public events affect social relations, decision quality, and public safety. The first chapter examines the persistence of historical religious conflict in contemporary Hindu–Muslim relations in India. The second chapter studies how time pressure affects decision quality in online chess. The third chapter analyzes the localized traffic-safety externalities of NFL game days. Across these settings, the dissertation uses large-scale data and quasi-experimental research designs to distinguish causal effects from selection, spatial concentration, and persistent local conditions.
The first chapter asks whether historical …
350 Years Later: A Creation Lens On The Birth Of Bacteriology, Alan L. Gillen
350 Years Later: A Creation Lens On The Birth Of Bacteriology, Alan L. Gillen
Faculty Publications and Presentations
No abstract provided.
Elemental Analysis Of Upper Devonian To Lower Mississippian Organic-Rich Mudstone Cores From Kentucky By Portable X-Ray Fluorescence (Pxrf), Alex M. Washburn
Elemental Analysis Of Upper Devonian To Lower Mississippian Organic-Rich Mudstone Cores From Kentucky By Portable X-Ray Fluorescence (Pxrf), Alex M. Washburn
KGS Research Data Set
This dataset contains high-density portable X-ray fluorescence (pXRF) elemental analyses of 1,867 m (6,125 ft) of Upper Devonian to Lower Mississippian organic-rich mudstone cores from Kentucky. Analyses were collected from cores across the Illinois Basin, Cincinnati Arch, and Appalachian Basin to support regional evaluation of elemental variability, chemostratigraphy, and redox-sensitive trace-metal enrichment in Devonian–Mississippian mudstone successions. All measurements were conducted using a Bruker Tracer 5 pXRF analyzer with the factory “Mudrock Air” calibration, using analytical settings optimized for both low-atomic-number elements and transition metals/redox-sensitive trace elements. Reference materials SARM-41 and SGR-1 were analyzed throughout the analytical sequence to monitor instrument …
Evaluating Acoustic Deterrents For Reducing Migratory Bird Collisions With Buildings, Jenna Brewer, Shane Oberloier, Annette Prince, David B. Stone, Jared Wolfe
Evaluating Acoustic Deterrents For Reducing Migratory Bird Collisions With Buildings, Jenna Brewer, Shane Oberloier, Annette Prince, David B. Stone, Jared Wolfe
Michigan Tech Publications
Migratory songbird populations are declining across North America, and collisions with glass-fronted buildings have become one of their leading causes of mortality. Finding practical ways to curb these collisions is a key conservation priority, but large-scale solutions remain elusive because retrofitting glass façades and enforcing lights-out policies are often prohibitively costly and logistically difficult. In this study, we focused on developing low-cost alternative deterrents that redirect migrants away from high-risk areas. We tested two acoustic deterrents: a broadband synthetic signal designed to mask nocturnal flight calls, which are important social cues for migrants, and a “predator” track featuring alarm calls …
Herbaceous Plants In Forest Ecosystems: One Hundred Fundamental And Applied Questions, Harikrishnan Venugopalan Nair Radhamoni, Michelle Elise Spicer, Marlyse C. Duguid, Liza S. Comita, Emilio Bruna, Andrew J. Andrade, Julia I. Burton
Herbaceous Plants In Forest Ecosystems: One Hundred Fundamental And Applied Questions, Harikrishnan Venugopalan Nair Radhamoni, Michelle Elise Spicer, Marlyse C. Duguid, Liza S. Comita, Emilio Bruna, Andrew J. Andrade, Julia I. Burton
Michigan Tech Publications
Aims: Herbaceous plants (herbs) found in the understory of forests contribute substantially to the biodiversity of these ecosystems, as well as being important socio-culturally, economically, and for advancing ecological theory. However, the ecology of herbs is less well understood compared with woody plants, despite evidence that herbs are physiologically and ecologically different. Similarly, herb research has focused on north temperate forests, with less information from forests in the tropics and Global South. Understanding this knowledge gap, and recognizing the critical importance of expanding and streamlining the scope of research on forest herbs, we set out to identify 100 fundamental and …
The Bridwell Quarterly, Issues 32 & 33, Spring-Summer 2026, Michelle S. Ried, Anthony Elia
The Bridwell Quarterly, Issues 32 & 33, Spring-Summer 2026, Michelle S. Ried, Anthony Elia
Bridwell Library Publications
No abstract provided.
The Interwoven Dynamics Of Climate, Fire, Resilience And Orangutan Survival In Central Kalimantan’S Peat Swamp Forest, Putu Pujiantari
The Interwoven Dynamics Of Climate, Fire, Resilience And Orangutan Survival In Central Kalimantan’S Peat Swamp Forest, Putu Pujiantari
Graduate Theses and Dissertations
Tropical peat swamp forests are globally significant carbon reservoirs and biodiversity strongholds, yet they face escalating threats from climate change, fire, and anthropogenic disturbances. This dissertation investigates the interwoven dynamics of climate, fire, forest resilience, and orangutan survival in Central Kalimantan, Indonesia, a region which was transformed by the failed Mega Rice Project and recurrent catastrophic wildfires for decades. Using a multi-scale approach that integrates remote sensing time-series analysis (2001–2024),nlandscape-scale disturbance mapping (2005–2025), and fine-scale movement ecology, this research tests three core hypotheses: (1) moisture availability is the dominant climatic driver of wildfire activity, operating through non-linear thresholds; (2) post-fire …
Reflecting On Freedom: 250 Years Through The Eyes Of Wvu Alumni Artists Exhibition, Sally Brown, Livia Balan, Ken Hillberry, Yvette Mazza, Precious Burger, Margaret Rose Caro, Ron Hollingshead, Betsy Jaeger, Ruth Yang, Tom Ott, Nancy Swisher, Griffin Nordstrom, Ben Nelsen, Morin Nessim, Desiree Vu, Ali Printz, Tiera Joy Tanner, Eliza Siefert, Stephanie Alaniz, Raymond Thompson, Sue Byrd, Michael Vercelli, Lesley Cottrell, Penny Lipscomb, Joshua Lohnes, Kelly Watson, Hal Gorby, Judith Stitzel, Bonnie Brown, Bob Britten, Renee K. Nicholson, Ellen Rodrigues, Erik Herron, Mark Brazaitis, Alfgeir Kristjansson, Linda Rosefsky, Joseph Lupo, Beth Royall, Evy Wright
Reflecting On Freedom: 250 Years Through The Eyes Of Wvu Alumni Artists Exhibition, Sally Brown, Livia Balan, Ken Hillberry, Yvette Mazza, Precious Burger, Margaret Rose Caro, Ron Hollingshead, Betsy Jaeger, Ruth Yang, Tom Ott, Nancy Swisher, Griffin Nordstrom, Ben Nelsen, Morin Nessim, Desiree Vu, Ali Printz, Tiera Joy Tanner, Eliza Siefert, Stephanie Alaniz, Raymond Thompson, Sue Byrd, Michael Vercelli, Lesley Cottrell, Penny Lipscomb, Joshua Lohnes, Kelly Watson, Hal Gorby, Judith Stitzel, Bonnie Brown, Bob Britten, Renee K. Nicholson, Ellen Rodrigues, Erik Herron, Mark Brazaitis, Alfgeir Kristjansson, Linda Rosefsky, Joseph Lupo, Beth Royall, Evy Wright
Faculty & Staff Scholarship
In honor of the United States’ 250th anniversary, the 2026–27 WVU Alumni Art Show invites viewers to explore freedom and independence through the eyes of West Virginia University alumni artists. This exhibition gathers a rich spectrum of perspectives—personal, historical, political, and cultural—demonstrating that the meaning of liberty is neither fixed nor singular. The exhibit also includes community responses to the work.
Portraits, abstractions, text-based paintings, mixed media, ceramics, and quilts collectively reveal the diverse ways artists grapple with liberty: as memory and inheritance, as resistance and care, and as lived, ongoing practice. By presenting these perspectives side by side, the …
Perceptions Of Research Participation Among Underrepresented Groups: Insights Using Freelisting Methodology, Tamar Klaiman, Jasmine Silvestri, Emma Britez Ferrante, Dorothy Sheu, Adina Lieberman, Erich Dress, Modele Ogunniyi, Neal Dickert, Meghan Lane-Fall, Rosemary Frasso, Rachel Kohn
Perceptions Of Research Participation Among Underrepresented Groups: Insights Using Freelisting Methodology, Tamar Klaiman, Jasmine Silvestri, Emma Britez Ferrante, Dorothy Sheu, Adina Lieberman, Erich Dress, Modele Ogunniyi, Neal Dickert, Meghan Lane-Fall, Rosemary Frasso, Rachel Kohn
College of Population Health Faculty Papers
BACKGROUND: Low enrollment and retention in clinical research disproportionately impact Black, Hispanic or Latinx, women, and rural populations, undermining generalizability and perpetuating health disparities. However, few studies have compared mechanisms driving underrepresentation across populations. Freelisting is a qualitative methodology that elicits lists of terms, explores perspectives about domains, and identifies common themes within groups with shared characteristics; however, it has not been systematically applied to understand research participation across underrepresented populations.
OBJECTIVE: To explore perspectives on clinical research participation across underrepresented populations using freelisting methodology to ultimately inform culturally-responsive recruitment strategies.
METHODS: We conducted a web-based freelisting survey among adults …
Donor-Derived Cell-Free Dna As A Prognostic Biomarker After Heart Transplantation: The Define-Ht Study, Palak Shah, Paul J. Kim, Kelly H. Schlendorf, David A. Baran, Monica M. Colvin, Adam D. Devore, Howard Eisen, Kambiz Ghafourian, Michael M. Givertz, Eileen Hsich, Jaime L. W. Kennedy, Evan P. Kransdorf, Jose N. Nativi-Nicolau, Jignesh Patel, Eleni Tseliou, Omar Wever-Pinzon, Andrew Doud, Michelle S. Bloom, Sandra A. Carey, Navchetan Kaur, D Giovanni Biagini, Kyle E. Marshall, Michael Olympios, Mandeep R. Mehra, Josef Stehlik
Donor-Derived Cell-Free Dna As A Prognostic Biomarker After Heart Transplantation: The Define-Ht Study, Palak Shah, Paul J. Kim, Kelly H. Schlendorf, David A. Baran, Monica M. Colvin, Adam D. Devore, Howard Eisen, Kambiz Ghafourian, Michael M. Givertz, Eileen Hsich, Jaime L. W. Kennedy, Evan P. Kransdorf, Jose N. Nativi-Nicolau, Jignesh Patel, Eleni Tseliou, Omar Wever-Pinzon, Andrew Doud, Michelle S. Bloom, Sandra A. Carey, Navchetan Kaur, D Giovanni Biagini, Kyle E. Marshall, Michael Olympios, Mandeep R. Mehra, Josef Stehlik
Department of Medicine Faculty Papers
BACKGROUND: Measurement of donor-derived cell-free DNA fraction (dd-cfDNA%) and donor quantity score (DQS) is a noninvasive biomarker of acute rejection in heart transplantation (HT). Its prognostic value beyond histopathology remains uncertain.
OBJECTIVES: This study sought to evaluate associations between donor-derived cell-free DNA (dd-cfDNA) and clinically meaningful outcomes using a composite endpoint of treated rejection, graft dysfunction, retransplantation, or death within 1 year post-HT.
METHODS: The DEFINE-HT (Development of Noninvasive Cell-free DNA to Supplant Invasive Biopsy in Heart Transplantation) was a prospective, observational study following adult HT recipients at 10 U.S. centers for 1-year post-HT; blood was collected for dd-cfDNA testing …