Digital Commons Network^™

A Trapped Rainbow, Cala E. Palmer

Calliope

No abstract provided.

Artificial Intelligence And Challenges Of Sustainable Library Services For Children And Young Adults In Nigeria, Ishioma Nwanapayi Iwegbue, Chigozie Blessing Mba

Library Philosophy and Practice (e-journal)

No abstract provided.

Signal And Substance: Why Methodological Sophistication Fails To Guarantee Inference, Aamir Rashid, Rizwana Rasheed

Publications and Research

Despite increasing analytical sophistication, empirical research in organization studies continues to suffer from fragile inference, uneven theoretical accumulation, and contested credibility. This paper seeks to explain why these problems persist by shifting attention from authors’ methodological choices to the evaluative dynamics of peer review. Adopting a conceptual and theory-analytic approach, the paper theorizes peer review as an inferential gatekeeping system. Drawing on research design, theory evaluation, and philosophy-of-science literatures, this study develops an analytical framework to examine how evaluative routines shape what constitutes empirical rigor during the review process. The analysis identifies five recurring reviewer blind spots: inferential scope inflation, …

Spontaneous Intracranial Hypotension With Negative Brain Mri Findings: A Systematic Review Of Diagnostic Strategies And Clinical Outcomes, Marina Romozzi, Giuseppe Garignano, Valid Rastegar, Francesco Onorati, Catello Vollono, Federico Tosto, Masahito Katsuki, Yasuhiko Matsumori, Francesco Signorelli

Student Papers, Posters & Projects

BACKGROUND: Spontaneous intracranial hypotension (SIH) is a debilitating syndrome typically characterized by orthostatic headache and classic brain MRI findings. However, brain MRI abnormalities are indirect manifestations of cerebrospinal fluid (CSF) volume depletion rather than direct evidence of the leak, and some patients may present with unrevealing or absent typical brain MRI findings, posing a considerable diagnostic challenge.

METHODS: A comprehensive search of PubMed/Medline, Web of Science, and Scopus was conducted to perform a systematic review, according to PRISMA guidelines, analyzing the available evidence on MRI-negative SIH (patients without typical SIH findings on their initial brain MRI), including its clinical features, …

Impact Of Middle Meningeal Artery Embolization Timing On Chronic Subdural Hematoma Resolution And Functional Outcomes, Bluyé Demessie, Muhammed Amir Essibayi, Hamza Adel Salim, Alireza Karandish, Nathan Farkas, Deepak Khatri, Neil Haranhalli, Amanda Baker, Richard Zampolin, Allan L Brook, Seon-Kyu Lee, Nimer Adeeb, James Grist, Fulvio Zaccagna, Yan-Lin Li, Davide Simonato, Diego Alejandro Ortega, Nicole Cancelliere, Jose Danilo Diestro, Dhairya Lakhani, Joseph Carnevale, Craig Schreiber, Atakan Orscelik, Zachary Abecassis, Spencer Raub, Georgios Sioutas, Giancarlo Salsano, Svetlana Kvint, Andrew Falzon, Vance Cantrell, Brian Holliday, Jefferson Abaricia, Pedram Maleknia, Leonardo Cruz-Criollo, Samantha Schimmel, Basel Musmar, Matthew Alexander, Jorge Rios Zermeno, Koul Prateeka, Ahmed Aljuboori, Dominik Vollherbst, Domagoj Gajski, Jared Cooper, Rahim Abo Kasem, Sami Al Kasab, Alejandro Spiotta, Fawaz Al-Mufti, Vladimir Kalousek, Markus Möhlenbruch, Luca Scarcia, Clemens Schirmer, Thien Huynh, Rabih Tawk, Fabio Settecase, Stavropoula Tjoumakaris, Pascal Jabbour, Kunal Vakharia, Mario Zanaty, Santiago Ortega-Gutierrez, Jesse Jones, Marco Colasurdo, Hussein Nasser, Sri Hari Sundararajan, Pascal Mosimann, Erez Nossek, Eytan Raz, Lucio Castellan, Bruno Del Sette, Caterina Michelozzi, Davide Saraceno, Pietro Panni, Visish Srinivasan, Jan-Karl Burkhardt, Gaultier Marnat, Pietro Mario Santini, Michael Levitt, Giuseppe Lanzino, Waleed Brinjikji, Jared Knopman, Tareq Kass-Hout, Julian Spears, Thomas Marotta, Max Wintermark, Vitor Mendes Pereira, Maurizio Fuschi, Adam Dmytriw, David Altschul

Department of Neurosurgery Faculty Papers

BACKGROUND AND PURPOSE: Chronic subdural hematoma (cSDH) affects approximately 20 per 100,000 individuals annually, with surgical recurrence rates of 10-20%. Middle meningeal artery embolization (MMAE) has emerged as a promising minimally invasive treatment, but the optimal timing remains unclear. We evaluated the association between MMAE timing and radiological and functional outcomes in cSDH.

METHODS: We conducted a retrospective multicenter international cohort study across 33 centres, including patients who underwent MMAE for cSDH between January 2018 and December 2024. Patients were stratified by timing from diagnosis: Q1 (≤1 day), Q2 (2 days), Q3 (3-6 days), and Q4 (>6 days). The …

Effectiveness Of Organic Amendments In Enriching Nitrogen In Compost Produced From Organic Fractions Of Market Waste Generated In Dar Es Salaam, Tanzania, Amani Bilula, Ally Mahadhy, Anthony Manoni Mshandete, Amelia Kivaisi

Tanzania Journal of Science

Low nitrogen (N) content remains a key limitation of compost derived from urban organic waste. This study evaluated the effectiveness of selected plant-based organic amendments in enhancing nitrogen content and improving compost quality. Four plant- based organic amendments, Leucaena leucocephala (BN01), Commelina benghalensis (BN02), Morus alba (BN03), and Helianthus annuus (sunflower) cake (BN04), were incorporated into market waste compost at ratios of 1:0.06:0.04, 1:0.06:0.25, and 1:0.06:0.5 (organic waste: sawdust: amendment). Composting was conducted using a 4 × 3 factorial design with three replicates per treatment (n = 36). Temperature, moisture, and pH were monitored throughout the composting period. Total nitrogen, …

4-H At The Hopkinton State Fair 2026, Alison Coleman

UNH Cooperative Extension

No abstract provided.

Recent Advances In Alzheimer's Disease: From Molecular Mechanisms To Therapeutic Strategies, Michelle D Rudman, Jason D Ulrich, David M Holtzman

2020-Current year OA Pubs

Alzheimer's disease (AD) remains the leading cause of dementia worldwide and an escalating global health crisis. The hallmark amyloid plaques and neurofibrillary tangles (NFT) are now known to be accompanied by a complex array of pathologies that culminate in neurodegeneration and cognitive decline. New disease-modifying therapies for AD can now slow cognitive decline through the removal of amyloid plaques from the brain, but treatments to stop or prevent cognitive impairment remain elusive. In this review, we summarize the most recent updates in AD research on pathologic disease mechanisms and therapeutic strategies, highlighting advancements in apolipoprotein E (APOE) biology, neuroimmunology, biomarker …

Tips For Growing Garden Vegetables In Utah: Soil Preparation, Gastone Makalaya, Josh Martin, Milena Oliveira

All Current Publications

To help Utah gardeners maintain healthy soils and enhance early vegetable production, this fact sheet provides practical guidance and tips on soil preparation for vegetable gardening.

Uncovering Phenotypic Expansion In Axin2-Related Disorders Through Precision Animal Modeling, Nathalie M Aceves-Ewing, Denise G Lanza, Paul C Marcogliese, Di Lu, Chih-Wei Hsu, Hirokazu Hashimoto, Matthew Gonzalez, Audrey E Christiansen, Tara L Rasmussen, Alex J Ho, Angelina Gaspero, Cher Sha, Mary E Dickinson, Bo Yuan, Brian J Shayota, Stephanie Pachter, Xiaolin Hu, Debra Lynn Day-Salvatore, Laura Mackay, Oguz Kanca, Michael F Wangler, Lorraine Potocki, Jill A Rosenfeld, Richard Alan Lewis, Hsiao-Tuan Chao, Brendan Lee, Lauren Blieden, Barry N Wasserman, Dorine A Bax, Nicola K Ragge, Sukyeong Lee, Undiagnosed Diseases Network, Baylor College Of Medicine Center For Precision Medicine Models, Shinya Yamamoto, Hugo J Bellen, Lindsay C Burrage, Jason D Heaney

Faculty, Staff and Students Publications

Purpose: Heterozygous pathogenic variants in AXIN2 (HGNC 904) cause oligodontia-colorectal cancer syndrome (ODCRCS). We identified five individuals with de novo, heterozygous variants (NM_004655.4:c.196G>A p.(Glu66Lys), c.197A>G p.(Glu66Gly), and c.199G>A p.(Gly67Arg)) in AXIN2. Common phenotypes among these individuals included ectodermal dysplasia, global developmental delay, microcephaly, and limb, ophthalmologic, and genitourinary abnormalities.

Methods: Structural modeling was performed to predict the impact of these variants on AXIN2. A prime editing N1 screen of mouse embryos was performed to test whether the p.Glu66Lys variant produces a phenotype. Drosophila models were used to test the effect of this variant on Wnt signaling.

Results: …

Problems And Possibilities Of Continuous Forage Production In Arid Subtropical Regions, Horst Patzold

IGC Proceedings (1977-2023)

The low animal performance and stocking rate in arid subtropical regions mainly depend on the discontinuity of forage production. In winter-raining steppes of North Africa, the cultivation or sod-seeding of adapted grasses, especially for forage production in the dry season. (summer), is recommended. For the dry savannas of West Africa with summer­raining, proposals are made for three different stages depending on the intensity of land use. They include a better use of grazing areas by transhumance, proposals for a ranching system, especially for meat production, and possibil­ities for milk production by stabling of cattle, including forage production under irrigation.

Optimal Combinations Off Our Large Herbivores For Short Grass Prairie, George M. Van Dyne

IGC Proceedings (1977-2023)

Diets of four large herbivores grazing together on a shortgrass prairie rangeland were studied. Cattle and bison consumed mainly grasses; sheep and antelope consumed mainly forbs. To maximize forage use, optimal grazing deter­mined by nonlinear programming would be 67, 20, 12, and I% of the forage grazed to be taken by cattle, bison, sheep, and antelope, respectively. Historically, this range has been grazed primarily by cattle. This study suggests more animal production could be attained with a mixture of herbivore species.

Aid To Rangeland Management. Mechanical Type Conversion Of Woodland Areas, William Gordon Leavell

IGC Proceedings (1977-2023)

Efficient land utilization is essential to meet the growing requirements of an expanding population. The large low-producing pinyon­juniper woodland of the United States offers potential for increased production to meet additional livestock, wildlife, and watershed needs. Through a multiple-use planning pro­cess which determines areas suitable for in­creasing production by mechanical conversion of vegetative types and an environmental anal­ysis procedure which determines the benefits and adverse impacts of such actions, decisions can be made to undertake treatment in an environmentally acceptable manner. The Bureau of Land Management has me­chanically converted over 200,000 hectares of pinyon-juniper to a more diversified and pro­ductive …

How To Organize Feeding In Complex Sheep Production Units In Mountain Areas Of The Kirghiz Ssr, K I. Isakov

IGC Proceedings (1977-2023)

In the Kirghiz SSR, the driving-pasture system is conditioned by the vertical zonation of the Tien Shan and Alai mountain ranges. A fun­damentally new form of livestock production must be practiced to meet the present-day material and technical level of agricultural production. Such a new form is sheep fanning without driving. lt can be introduced in many mountainous regions of the USSR, where "inner" and "outer" pastures are available. The major conditions for a pasture system without driving are the creation of complex sheep production units and the establishment of the necessary fodder base. Two types of sheep production units …

The Biological Performance And Efficient Utilization Of Artificial And Natural Grassland Areas In The Valleys And Mountainous Regions Of The Western Part Of Northern Tien Shan, N I. Zakharev, A A. Atabaev, L A. Golovina, L V. Koverga, N G. Kotysheva, I P. Lazarev, N S. Sotnikova, N N. Sycheva

IGC Proceedings (1977-2023)

Investigations over several years and numer­ous experiments • carried .. out under different aspects and in different geographical zones revealed the fundamentally new importance of perennial legume/grass mixtures under in­tensive cultivation and utilization. The intensive utilization of young plants in several cuts and cycles at a high level of agrotechnics allows to obtain high yields of best-quality green ma­terial that can be fed fresh or used for pro­ducing feeds of high biological value, especially in regard to the protein, carotene, and phos­phorus contents. Intensive cultivation and utilization of legume/grass mixtures allows by different tech­nologies to produce feeds of high value …

Studies Into Uses Of Natural Nardus Stricta L. Pastures, Totyu Totev, Konstantin Koev

IGC Proceedings (1977-2023)

Experiments were conducted over four con­secutive years, with the view to comparing controlled and unrestricted grazing by sheep. Controlled grazing was found to help increas­ing the green matter yield by 13.3 % and the hay yield by 12.5 %. The actual yield levels resulting from controlled grazing exceeded those ob­tained after unrestricted grazing by 32.5 % for green matter and by 31.5 % for hay. The utili­zation coefficient for green matter was higher by 12.5 %- A controlled grazing regime increased the consumption of real forage plants, such as Agrostis vulgaris, Festuca rubra V. Fallax, and Deschamps1a flexuosa, whereas forb …

Utilization Of Soil In Northern Latitudes, Vasil Ivanovich Ustinov

IGC Proceedings (1977-2023)

About half of the territory of the Soviet Union is located in the Far North and in regions with similar conditions, including the vast lands of the tundra and forest tundra as well as the various subzones of the taiga. More than 500 million hectares are considered as forage-bearing land: grazing for reindeer and other farm animals, hay land, and potential arable land. Many scientists believe that up to 5 million head of reindeer may be kept grazing these lands. In recent times, great attention has been paid to the rearing of horses, elks, and musk­oxes in northern latitudes. Measures …

Flood Adaptation And Productivity Of Savanna Grasses, E Gonzalez Jimenez, A Escobar

IGC Proceedings (1977-2023)

Savannas subjected to seasonal flooding occupy· vast areas of the Tropics. Above-ground bio­mass values for Venezuelan flooded savannas are high and related to the longer availability of water. C3 plants colonized the waterlogged unit and showed the highest productivity and nutritive value. This natural system permits a prolonged grazing season. These first results show the great potential for animal production of this ecosystem, stressing the need for coor­dinated research efforts in order to gain a better understanding of it.

Nitrogen Status Of A Shortgrass Prairie, Pasture Ecosystem, Robert G. Woodmansee, Jerrold L. Dodd, Rudolph A. Bowman, Charles E. Dickinson

IGC Proceedings (1977-2023)

Nitrogen was partitioned among soil organic matter, living and dead plant material, micro­organisms, above-ground and below-ground animals, and mineral N in a shortgrass prairie, pasture ecosystem in eastern Colorado, USA Soil organic matter contained the largest amount of N (89.5 %), and dead plant material contained 6.8 % of the total N in the system. Living organisms contained 3.4 % of the N in the ecosystem. Mineral N accounted for 0.2 %. Less than 1.0 % of the N in the system was located above ground. The amount of N im­mobilized in animals was small.

Treatment, Recognition, And Prevention Of Communicable Conditions In The Summer Camp Setting, Matthew Labkovski

CompassPoint

No abstract provided.

Your Camp Health Services Essential Tips For Success, Bev Unger

CompassPoint

Camp health services are the cornerstone of health and safety. From managing small injuries to medical emergencies, it is the area of camp that encompasses care, safety, health promotion, injury prevention, illness and injury management, and the overall “make you feel better” place. Hiring the right health staff and setting them up for success with appropriate tools, staff training, and solid processes are key to the success at summer camp. When there is a crisis, an injury, or an illness, the outcome can be devastating if not managed in a timely and effective way. Creating the best health center experience …

Molecular Detection Of Chlamydiales In Captive Zoo Animals At Songkhla Zoo, Southern Thailand, Rawikan Inchuai, Sunisa Khongthong, Boontarikaan Wititkornkul, Naruepan Wongpluksin

The Thai Journal of Veterinary Medicine

Several species of Chlamydia are recognized as significant zoonotic pathogens that infect a wide range of hosts, including humans. This study aimed to investigate the occurrence and genetic characteristics of Chlamydiales–related bacteria in captive animals at Songkhla Zoo, southern Thailand. A total of 92 cloacal and rectal swab samples were collected from mammals (n = 22), birds (n = 55), and reptiles (n = 15). Genomic DNA was screened using polymerase chain reaction (PCR) targeting the Chlamydiales 16S rRNA gene and the ompA gene specific for Chlamydia psittaci. Positive amplicons were subjected to Sanger sequencing and phylogenetic analysis. A …

Identification Of Active Compounds And Antidiabetic Activity Of Red Shoot (Syzygium Myrtifolium) Leaves Extract With In Vitro And In Silico Methods, Muhamad Iqbal Prakoso, Siti Warnasih

Pharmaceutical Sciences and Research

Diabetes mellitus (DM) is a chronic metabolic disease that affects approximately 537 million people worldwide (1 in 10 individuals), and its prevalence is projected to reach 783 million by 2045. One of the plants that has the potential to be an antidiabetic is red shoots (Syzygium myrtifolium) since it contains various secondary metabolite compounds such as flavonoids, triterpenoids, steroids, saponins, phenolics, and anthocyanins. This study aimed to evaluate the antidiabetic properties of red shoot leaves extract and to identify and predict interactions between its active compounds and the α-glucosidase receptor. Ethanol, ethyl acetate, and n-hexane extracts of red …

Gene Dosage Differences And Non-Linear Impacts On Complex Traits., Craig Smail

Manuscripts, Articles, Book Chapters and Other Papers

Large differences in gene dosage are usually associated with opposite phenotypic effects but show a bias toward one direction in aggregate genome wide. Milind et al. suggest that this is explained by differences in regulatory mechanisms by which genes influence phenotypes and by the increased selective pressures acting on a subset of genes.

Avian Conservation And Translocations In The Mariana Archipelago, John V. Bender

Dissertations

Island birds are among the world’s most imperiled vertebrates, and conservation translocations are increasingly used to combat threats, but their success depends on understanding the mechanics of whether and how to conduct translocations effectively. In the Commonwealth of the Northern Mariana Islands, native forest birds persist across a chain of islands where habitat degradation and loss, invasive species, and extreme weather create persistent conservation challenges. For my dissertation, I investigated how avian conservation programs and translocations can be planned, implemented, and improved under biological, logistical, and social uncertainty. For Chapter 1 I analyzed 15 years of avian translocations across seven …

Unbiased Avidity-Based Isolation Of Antigen-Specific T Cells, Amanda Montoya, Meredith L Frank, Peixin Jiang, Hui Nie, Minying Zhang, Emily Bontekoe, Jared K Slone, Ludovica L Posta, Sofia Rosy Caterina Sorice, Tina Cascone, Maura Gillison, Don L Gibbons, Jianjun Zhang, Eleonora Dondossola, Lydia Kavraki, Pamela L Wenzel, John V Heymach, Alexandre Reuben

The Brown Foundation: Institute of Molecular Medicine

Background: Cancer immunotherapies have significantly improved treatment efficacy and patient survival by exploiting antigen-specific T cells to eliminate cancer cells. However, current approaches for identifying and isolating antigen-specific T cells typically require prior knowledge of target antigens, limiting discovery, and reducing the ability to consistently detect rare tumor-reactive T cells. We therefore sought to develop an unbiased platform for the identification and enrichment of antigen-specific T cells using naturally processed and presented tumor antigens.

Methods: We developed ATTACH (Assessment of T cells Tethered to Antigen Class I Histocompatibility), a microfluidic platform that applies controlled shear stress and leverages tumor cells …

Spatiotemporal Trends In Schistocephalus Solidus Infection Among Populations Of Alaskan Threespine Stickleback (Gasterosteus Aculeatus), A.M Wohlleben, Neva Meyer, N.C. Steinel

Biology

Understanding the dynamics of host-parasite interactions is essential for uncovering the ecological and evolutionary processes shaping natural populations. In this study, we investigated the spatial and temporal patterns of prevalence of the cestode Schistocephalus solidus in 4 Alaskan populations of threespine stickleback (Gasterosteus aculeatus) over 11 years (1996 to 2006). Additionally, we assessed host tolerance through key indicators such as the Parasite Index and the presence of fibrotic scar tissue, a specialized form of resistance in this system. We observed fibrosis formation in both infected and uninfected fish across all populations, with notable year-to-year variability in Cornelius Lake. Here, fibrosis …

The Association Between Food Insecurity, Housing Insecurity, Self-Care Practice And Depression Among Black Immigrants In The United States, Beatrice Ngozi Mbaocha

Walden Dissertations and Doctoral Studies

The prevalence and poor prognosis of depressive symptoms remain significant among adult Black immigrants in the United States. This study examined the complex interplay between food insecurity, housing insecurity, self-care practices, and depression among adult Black immigrants in the United States. Grounded in the socioecological model, this quantitative cross-sectional study analyzed data from N = 469 noninstitutionalized Black immigrant adults (54.2% female, 45.8% male) using the 2023 National Health Interview Survey. Binary logistic regression was employed to assess the probability of depressive symptoms as a function of food insecurity, housing insecurity, and self-care practices, controlling for age, gender, and employment …

Online Decoding Of Rat Self-Paced Locomotion Speed From Eeg Using Recurrent Neural Networks, Alejandro De Miguel, Nelson Totah, Uri Maoz

Psychology Faculty Articles and Research

Objective. Accurate and reliable neural decoding of locomotion holds promise for advancing clinical applications such as rehabilitation and prosthetic control, as well as for understanding neural correlates of action. Recent studies have demonstrated successful decoding of locomotion kinematics across species in motorized treadmill settings. However, efforts to decode locomotion speed directly and continuously in more natural contexts—where pace is self-selected rather than externally imposed—are scarce, and those that exist generally achieve only modest accuracy and require intracranial implants. Here, we aim to decode self-paced locomotion speed non-invasively and continuously using cortex-wide electroencephalography (EEG) recordings from rats. Approach. We introduce an …

Integrating Nutrition And Stress Into Life History Stages Of Wild Free-Ranging Female Pronghorn, Cole A. Bleke, Eric M. Gese, Juan J. Villalba, Shane B. Roberts, Susannah S. French

Wildland Resources Student Research

Studies addressing seasonal changes in diet quality and hormones are important for understanding the interactions between ecology and physiology. We collected fecal samples from free-ranging adult female pronghorn (Antilocapra americana) to examine the relationships between indicators of nutrition and glucocorticoid activity. This occurred during three population-level, life-history-correlated sampling periods across five subpopulations. We evaluated nutrition via fecal nitrogen, fecal 2,6-diaminopimelic acid (DAPA), and assessed glucocorticoid activity using fecal glucocorticoid metabolites (FGM). We found positive relationships between fecal nitrogen and DAPA, whereas DAPA and fecal nitrogen with FGM varied in influence and strength, depending upon life history stage. Generally, …