Fecal Showdown - Fit Vs. Colonoscopy: Which Is Better In Colorectal Cancer Detection?, Vanessa A. Arenas, Virn Warndahl

Physician Assistant Capstones, 2020-current

Abstract

Objectives

Colorectal cancer (CRC) is a leading cause of cancer-related deaths in the United States, with most cases occurring in individuals aged 50 years and older. Effective screening is essential for early detection and improved patient outcomes. This paper compares two widely used CRC screening methods—fecal immunochemical testing (FIT) and colonoscopy—primarily in terms of colorectal cancer detection, but also considers adherence and diagnostic yield.

Methods

A search was conducted using PubMed and CINAHL to identify relevant studies comparing FIT and colonoscopy. Articles were included if they were randomized controlled trials (RCTs) or clinical trials published after 2020, involved subjects …

Does Ekg Better Predict Scd Than Traditional Preparticipation Evaluation?, Melanie Hux, Collin Hensien

Physician Assistant Capstones, 2020-current

Introduction: Pre-participation evaluations (PPE) in athletics attempt to reduce the incidence of preventable disease such as sudden cardiac death (SCD) during sports by identifying individuals who may be more susceptible. The purpose of this study was to evaluate the question: does electrocardiogram (EKG) obtained during preparticipation evaluation better identify predictors of sudden cardiac death than history and physical exam in adolescent athletes?

Methods: PubMed was used for this literature search with MESH terms to narrow down an initial search of 143 results to 3 articles that satisfied research criteria. MESH search terms included sudden cardiac death, electrocardiography, physical examination, and …

The Effect Of Platelet Rich Plasma Injection Vs. Steroid Injection On Plantar Fasciitis, Brian Nangle, Lasya Ampaty

Physician Assistant Capstones, 2020-current

Objective: Assess the ability of platelet-rich plasma (PRP) injections to perform better than steroid injections in a population refractory to conservative treatment. Design: Systematic literature review. Methods: Searches were done in PubMed and Scopus, utilizing the terms platelet-rich plasma, steroid injection, and plantar fasciitis. The following limits and terms were used: published in the last 5 years, randomized control trial, used both VAS scale and AOFAS scale. Results: All 3 studies demonstrated that PRP injections allowed more pain reduction and improved stability when compared to steroid injections. Conclusion: PRP injections offer a well-tolerated, minimally invasive procedure for patients refractory to …

Non-Destructive Characterization Of Ion Irradiated Yttrium Hydride For Microreactor Applications, Ryan E. Pena

Nuclear Engineering ETDs

As energy demands increase, nuclear reactors, especially microreactors, become a promising energy source. These reactors run at high temperatures (>280°C), requiring moderators that can endure these environments. Yttrium hydride is a possible moderator, but little is known about the material’s phase stability and hydrogen retention under irradiation. Through the use of a gold ion beam, samples with stoichiometries ranging from 1.6 to 2.0 were irradiated and tested. Through Vickers hardness testing, a model was created showing a correlation between hydrogen content and hardness. Raman spectroscopy showed high temperature and irradiated samples have significant hydrogen loss. XRD quantified this hydrogen …

Sequential Low Dose Proton Irradiation And Nanomechanical Testing To Understand Mechanical And Microstructural Property Changes In Alloy 709, Abhishek Kc

Nuclear Engineering ETDs

Alloy 709, a 20Cr25Ni alloy, is an advanced austenitic steel designed for next generation sodium fast reactors. Preliminary studies have shown the potential of Alloy 709 in sodium fast reactors. In this study, Precipitate Treated Alloy 709 specimens are irradiated with 2 MeV H⁺ at 500 °C from 0.0057 dpa to 1.7 dpa. Electron microscopy characterization techniques are used to understand the effects of radiation on mechanical properties as well as microstructure of Alloy 709. The microstructure did not show formation of voids, amorphization of precipitates, or increase in grain size up to 1.7 dpa. Correspondingly nano-indentation and micro-pillar …

Coupled Adjoint-Based Perturbation Theory For Dynamics And Heat Transfer Multiphysics For Nuclear Transients, Alexis Maldonado

Nuclear Engineering ETDs

Nuclear reactor multiphysics modeling and simulation (M&S) enable advanced reactor design by analyzing how systems will react over time to various configurations, scenarios, and perturbations. However, high-fidelity coupled transient M&S for reactor cores are computationally expensive, making robust analyses challenging. This work develops a Coupled Adjoint-based Perturbation Theory for dynAmIcs and heat traNsfer (CAPTAIN) framework to rapidly quantify the impact of uncertainty to overall transient responses by generating sensitivity coefficients for temperature, power, and delayed neutron precursor concentrations using forward and adjoint solutions. This work presents an initial proof of principle, verified with direct perturbations to several inputs. Furthermore, this …

A Risk-Informed Approach To Performing The Pre-Closure Safety Analysis For The Deep Borehole Disposal Of Radioactive Waste, Jennifer Elizabeth Leute

Nuclear Engineering ETDs

Deep borehole disposal is an emerging concept which involves disposing of radioactive

waste in boreholes several kilometers deep then backfilling to minimize radionuclide

transport and distribute weight. Unfortunately, little documentation exists on borehole

safety case development, especially for pre-closure operations. This study aims to close

this gap by proposing a graded approach matrix based on consequence, maturity, and

complexity. Two case studies are used to demonstrate this application: Hanford CsCl

capsules and spent PWR assemblies. Simulations are used to predict potential for dose

exposure, revealing CsCl capsules have a much higher potential for being above the 5

rem public dose …

Dermal Lymphatic Carcinomatosis As A Cutaneous Metastasis From Epidermal Growth Factor Receptor-Positive Lung Adenocarcinoma: A Case Report, Sarah A. Hemelt, Jonathan M. Joseph, Nicholas Culotta

School of Medicine Faculty Publications

Cutaneous metastases are an uncommon but clinically significant manifestation of internal malignancies. We present a rare case of dermal lymphatic carcinomatosis arising from epidermal growth factor receptor (EGFR)-positive lung adenocarcinoma, a presentation that may closely mimic inflammatory dermatoses and indicate therapeutic resistance or disease progression. We describe the clinical course of a 65-year-old woman who developed a violaceous cutaneous metastatic lesion beneath the left breast during treatment for metastatic lung adenocarcinoma. This case highlights the importance of recognizing cutaneous signs as indicators of disease progression and emphasizes the diagnostic challenges and prognostic implications of cutaneous metastases in lung cancer.

Modeling Mineral Redistribution In Biological Tissue Using Apple As An In Vitro Analogue, Daler Djuraev, Ali Algemsh, Halima Alazeb, Zeenia Ahmed

Publications and Research

This project aims to model mineral (ion) redistribution that occurs in human soft tissue after injury or mechanical/thermal stress. Because direct, repeatable in vivo measurements are difficult, we use apples as an in vitro analogue: their mineral content is relatively uniform and the tissue can be cut, dried, and repeatedly imaged under controlled conditions. Using X-ray imaging, we tracked how minerals in apple tissue move toward damaged regions immediately after cutting, and how subsequent drying at room temperature drives a redistribution toward the central core. We also observed that biological degradation (decay) alters mineral density over time, indicating that even …

Using Vaginal Cytology To Confirm Estrus In Swine - Pilot Study, Carly J. Johnson

Honors College Theses

This study aims to determine whether there is a correlation between cellular changes observed in vaginal cytology and the physical signs of estrus in swine. Vaginal cytology is a technique commonly used in dogs, cats, and rodents, and if proven effective in swine, it could serve as a practical tool for producers to confirm estrus status and improve reproductive management.

Assessment Of Fish Community Dynamics, Movement, And Morphology In Relation To Stream Barriers In The Upper Illinois Bayou Watershed, Risa Mccollough

ATU Theses and Dissertations 2021 - Present

Intermittent streams are increasingly recognized as vital components of river networks by supporting dynamic fish communities shaped by variable hydrology and habitat connectivity. They are becoming increasingly vulnerable to fragmentation by anthropogenic activities, namely road crossings, dams, and climate shifts that intensify seasonal drying. In response, I conducted two studies in the Illinois Bayou watershed in Arkansas to assess the effects of fragmentation on fish community dynamics and morphology in intermittent streams.

In the first study, I examined temporal fish community dynamics across two barriers: a natural waterfall in Dare Creek and a low-water crossing in Dry Creek. Simultaneously, I …

Travels In West Africa: A Critical Edition, Erere Iwhi

Student Works

First published in 1897, Mary Henrietta Kingsley’s Travels in West Africa became one of the most influential travel narratives of the Victorian era, changing the way British audiences encountered accounts of West Africa and its peoples. This critical edition examines the book not only as a travel narrative but also as a material artifact shaped by the historical, publishing, and cultural networks that guided its production, circulation, and reception. Extending its analysis beyond Kingsley's experiences of exploration, this edition investigates the forces behind the book’s creation, including Kingsley’s intellectual development, her identity as an independent female traveler and writer, and …

A Multivalent Capsule Vaccine Protects Against Klebsiella Pneumoniae Bloodstream Infections In Healthy And Immunocompromised Mice, Paeton L Wantuch, Lloyd S Robinson, Cory J Knoot, Isra Darwech, Aline M Matsuguma, Evgeny Vinogradov, Nichollas E Scott, Christian M Harding, David A Rosen

2020-Current year OA Pubs

Klebsiella pneumoniae is a leading cause of nosocomial infections, bacteremia, and worldwide mortality. Further, a drastic rise in antibiotic-resistant isolates poses an urgent threat to humanity. Unfortunately, despite its clinical importance, a licensed K. pneumoniae vaccine is not yet available. Here, we report on the production and characterization of the broadest K. pneumoniae capsule bioconjugate vaccine to date. We tested this vaccine for its immunogenicity, functionality, efficacy, and antibody durability against a variety of K. pneumoniae isolates in a murine bacteremia model. We also established an immunocompromised murine model of bacteremia to better recapitulate human infection and tested our vaccine's …

Investigating The Fatigue Behavior Of Inconel 939 And Inconel 718 Through Micromechanical Testing, Mohammad Hossein Shahini

LSU Doctoral Dissertations

A detailed evaluation of fatigue crack growth (FCG) in a silicon-modified Inconel 939 alloy, fabricated via laser powder bed fusion additive manufacturing (L-PBF AM), was performed using cyclic bending tests on pre-notched microscale cantilevers with a cross-sectional dimension of 25 µm × 25 µm. To our knowledge, this study is the first to demonstrate that such microscale cantilever tests can effectively capture both the threshold and Paris-law regimes of FCG, despite the limited specimen size. The precise fabrication of these small-scale specimens allows for controlled fatigue crack propagation relative to the microstructure while minimizing the presence of volumetric defects. Notably, …

Cardiometabolic And Molecular Adaptations To 6-Month Intermittent Fasting In Middle-Aged Men And Women With Overweight: Secondary Outcomes Of A Randomized Controlled Trial, Ruteja A Barve, Nicola Veronese, Beatrice Bertozzi, Valeria Tosti, Maria Lastra Cagigas, Francesco Spelta, Edda Cava, Laura Piccio, Dayna S Early, Richard D Head, Luigi Fontana

2020-Current year OA Pubs

Intermittent fasting (IF) has gained attention as a potential intervention for cardiometabolic health, though its long-term effects remain unclear. In this randomized clinical trial, we assessed the impact of 6 months of IF on body composition, cardiovascular risk factors, and related molecular pathways in middle-aged (30-65 years) men and women with overweight (BMI 24.8-35 kg/m²). In this trial, 41 participants were randomized to either an intermittent fasting (IF) intervention or to maintain their habitual diet. The primary outcome (circulating CRP concentration) was previously reported; here, we present exploratory analyses focusing on metabolomic and transcriptomic responses. IF led to an 8% …

Patient-Derived Ovarian Cancer Models Provide Insight Into Cancer Cell-Intrinsic And Immune Cell-Dependent Effects On Therapeutic Response, Parisa Nikeghbal

Biomedical Sciences ETDs

Ovarian cancer is the most lethal gynecologic malignancy, largely due to late diagnosis and resistance to chemotherapy. This dissertation applies patient-derived organoids (PDOs), xenograft-derived organoids (PDXOs), and humanized xenografts (huPDX) to investigate therapeutic responses and immune interactions. Organoids were shown to retain critical features of the original malignancy. Across platinum-sensitive, -resistant, and -refractory cases, both PDOs and PDXOs exhibited drug sensitivities that aligned with patients’ clinical classifications. Building on this foundation, a drug screen revealed novel strategies. Auranofin restored platinum sensitivity in Notch3-active models, afatinib broadly reduced viability, and adavosertib–gemcitabine and sorafenib–topotecan combinations produced synergy. Extending this work, immune interactions …

Parameter-Efficient Multimodal Adaptation: Ocr-Integrated Lora For Textvqa And Captioning, Karthik Ganesh Malini

Master's Theses

Vision-Language Models (VLMs) have emerged as transformative technologies for multimodal AI, yet they face significant hurdles in processing text-rich images required for enterprise applications like document understanding, medical imaging, and industrial inspection. Current VLMs struggle with accurate text extraction and reasoning, often exhibiting high hallucination rates and poor Optical Character Recognition (OCR) token utilization. To address these limitations, this research presents a comprehensive framework for optimizing parameter-efficient Low-Rank Adaptation (LoRA) fine-tuning strategies on state-of-the-art architectures, including LLaVA-1.5 and BLIVA-FlanT5. Our methodology integrates enhanced OCR token utilization, faithful caption generation, and specific hallucination mitigation techniques. We employ a multi-dimensional evaluation protocol …

Instrumental Music Educator Strategies To Reduce Or Remove Participation Barriers For Middle School Students, Rachel A. Gorden Mercer Ed.D

Doctorate in Education

Scholars have found that students who participate in instrumental music programs achieve higher academic levels, have better attendance, and build stronger community connections than students who do not participate. This dissertation examines successful strategies for increasing participation in instrumental music programs by reducing socioeconomic barriers, enhancing instrument access, creating ensemble opportunities, and fostering a positive culture within the instrumental program for students during the middle school years. Music educators have found successful strategies to recruit and retain students despite the barriers they encounter.

Researchers have investigated the benefits of participating in instrumental music and the reasons why students discontinue their …

Design And Evaluation Of The Influence Of Mutual Induction On Microbial Electrolysis Cell Performance And Biogas Production, Ashley L. Blackwell

Civil Engineering ETDs

Microbial electrolysis cells (MECs) present a pathway for energy recovery in wastewater treatment by converting organic substrates into methane or hydrogen. Traditional MEC designs typically rely on physical electrode contacts and expensive materials, which restrict their scalability. This study introduces the first induction-based MEC that uses mutual inductance between an external copper wrap and an internal coil to generate a fluctuating electrical potential, removing the need for expensive electrodes. The induction-stimulated reactor showed faster total organic carbon removal and a higher CH4/CO2 ratio compared to a conventional anaerobic digester, indicating improved carbon-to-methane conversion, although total gas yield remained similar. Microbial …

Graph Based Planning With Guarantees, Trazon Tyrik Jimerson

Mechanical Engineering ETDs

This thesis presents two graph-based methods with formal guarantees for motion planning and routing. First, the invariant-set motion planner (ISMP), which uses constraint admissible positive invariant (CAPI) sets of closed-loop dynamics, is adapted for spacecraft attitude planning to avoid moving keep-out zones. Contributions include time bounds for maneuvers via exponential stability, a single-stage reachability graph from one-step backward reachable CAPI sets, and its multi-stage expansion to certify node safety over time. Simulations verify safe attitude control with moving obstacles. Second, we formulate a convex optimization problem over a network for evacuation planning with operational constraints such as helicopter capacity and …

Real-Time Frequency Tuning Of Kinetic Energy Harvesters Via System Mass Adjustment, Rahul Adhikari

Mechanical Engineering ETDs

This research presents a method for real-time frequency tuning of piezoelectric kinetic energy harvesters through system-mass adjustment. Custom 3D-printed proof masses with cavity arrays were used to redistribute solid or liquid mass, enabling controlled modification of resonant frequency. Experimental studies using microparticles and liquids—including water, silicone oil, and sodium polytungstate—demonstrated an achievable tuning range of 115.27 Hz with sub-hertz resolution (< 0.1 Hz), confirming precise and repeatable frequency control. Finite-element modeling guided design optimization, while a microfluidic channel system enabled automated liquid filling for real-time operation. A MATLAB-based EH_Tuning application was developed to visualize and predict frequency responses. The combined …

Design And Development Of Evacuated Photovoltaic-Thermal Systems For Efficient Cogeneration Of Heat And Electricity, Behnam Roshanzadeh

Mechanical Engineering ETDs

In conventional PV systems, most of the solar energy is dissipated into the environment as heat. Accordingly, hybrid Photovoltaic-thermal systems have been developed to utilize the waste heat from PV cells for various thermal applications. However, most PVT systems suffer from low thermal performance compared to solar thermal collectors, as the absorber plate in PVT systems is partially or fully covered by PV cells. This dissertation focuses on improving the thermal performance of PVT systems by introducing the evacuated PVT systems.

An evacuated-tube PVT system was designed and simulated for domestic hot water supply. The evacuated-tube PVT system demonstrated 40% …

Efficacy Of Oil And Gas Production Site Remediation In U.S. Arid/Semi-Arid Regions, Skye Ontiveros

Architecture and Planning ETDs

Oil and gas production (OGP) is expanding, paralleled by its polluting leaks and spills (LS), and outpaced by its waste. This raises the question: Does remediation of LS occur effectively when needed to protect the environment and public, particularly in major producing regions like arid/semi-arid regions (ASAR), which account for approximately 72% of US oil and 42% of gas production? To answer, a review of the eight largest national remedial laws, sourced from the Code of Federal Regulations (CFR), identified 14 OGP exemptions for remedial determinants (RDs): factors affecting remedial frequency and efficacy (e.g. LS monitoring and chemical disclosure). An …

Pediatric Obstructive Sleep Apnea And The Role Dental Hygienists Play In Achieving Optimal Health And Quality Of Life: A Pilot Study, Kari S. Roth

Dental Hygiene ETDs

ABSTRACT

The purpose of this study was to evaluate the current practice, confidence, barriers, and experience of dental hygienists who screen or identify signs, symptoms, and risk factors of those who struggle with pediatric obstructive sleep apnea. This study was designed to provide a brief perspective to identify gaps or needs for improvement in dental hygiene practice. Members of the American Dental Hygienists’ Association participated in an electronic survey. While 231 participants responded, most reported some familiarity with obstructive sleep apnea in children, but many are unaware of guidelines from other professional organizations for screening protocols. Results depict a lack …

Hearing Their Voices: Exploring Parent Perspectives Regarding Augmentative And Alternative Communication In Home And Community Contexts, Heather Rose Diluzio

Special Education ETDs

Parents of children who have extensive support (ESN) who use augmentative and alternative communication (AAC) have reported challenges in supporting their children’s communication in home and community contexts. This qualitative interview study explored the perspectives of six mothers of children with ESN who use aided AAC to examine the supports families have, or would like to have, to integrate aided AAC meaningfully into their child’s communication in home and community settings. Findings revealed that these parents were the primary force behind their child’s access to aided AAC due to limited support from formal systems and professionals. Themes included: parents’ deep …

395 East 151 St. Corp. V. Mhany Cluster Housing Development

All Decisions

In a rent-stabilized holdover for failure to sign a lease renewal, the court granted the occupant's motion to dismiss the petition against her (as "Jane Doe") for improper use of a pseudonym under CPLR 1024. The landlord claimed ignorance of her identity, but evidence showed it knew her name, having collected HRA payments on her behalf, and that she had interacted with management. The court denied the landlord's request to sua sponte join the occupant, finding her identity was known pre-commencement. The proceeding continues against the named tenant.

Fake News Y Redes Sociales: Cómo El Algoritmo En Torno A La Migración Afecta La Salud Mental, Maria F. Alarcon

Capstones

Las redes sociales son la principal fuente de información para migrantes latinos en Estados Unidos, pero también son un terreno fértil para fake-news que afectan la salud mental y desinforman.

“Sin Tener Que Gastar”: Un Restaurante Gourmet En Nueva York Donde Pagas Lo Que Puedas, Oscar Alberto Flores

Capstones

Community Kitchen es un restaurante piloto gourmet en el Lower East Side de Nueva York que funciona bajo un modelo de “paga lo que puedas”, creado por el reconocido periodista gastronómico Mark Bittman. Ubicado en un vecindario marcado por una profunda desigualdad económica y altos niveles de inseguridad alimentaria, el proyecto busca demostrar que la comida de alta calidad puede ser accesible para personas de todos los ingresos. A través de un menú sostenible, precios flexibles, apoyo a agricultores locales —en su mayoría BIPOC— y salarios justos para jóvenes cocineros, Community Kitchen combina gastronomía, justicia social y comunidad. En …

Halt Under Threat Why Legislators Must Demand Compliance Before Change A Playbook For Action, Vanda Seward

Capstones

This playbook examines the implementation of New York State’s Humane Alternatives to Long-Term Solitary Confinement (HALT) Act and presents evidence demonstrating that the law has not been fully or consistently enforced by the New York State Department of Corrections and Community Supervision (NYSDOCCS). Drawing on findings from the New York State Inspector General, the Correctional Association of New York, the Justice Center, court rulings, and community testimony, the analysis documents persistent violations, including excessive and illegal use of solitary confinement, inadequate documentation, failures to protect vulnerable populations, and insufficient accountability for staff misconduct. The playbook critically evaluates the recommendations of …

What’S That Smell? It’S Climate Change!, Perry Gregory

Capstones

Climate change is going to make New York City smell worse. Reporter Perry Gregory breaks down the process of olfaction and explains how heat affects what we smell. The piece features a collage of voices of New Yorkers describing the current smell profile of the city. The report features insight from several Atmospheric Scientists into why New York City is getting hotter and more humid, and how those climate changes will make the existing smells of the city stronger, and worse. The most economically vulnerable New Yorkers, who cannot afford air conditioning to buffer them from heat, will be the …